s CASE FILES CATARACT SURGERY AFTER A PHAKIC IOL A patient with high myopia wishes to retain excellent intermediate visual acuity without experiencing glare.

BY AUDREY R. TALLEY ROSTOV, MD; RUPERT MENAPACE, MD, FEBO; SIMONETTA MORSELLI, MD; MAJID MOSHIRFAR, MD; MARGARET H. SHMUNES, BS; AND SHERI ROWEN, MD, FACS

CASE PRESENTATION

A 49-year-old man presents for a cataract surgery consultation. The patient reports decreased visual acuity in each . He received a Verisyse phakic IOL (Johnson & Johnson Vision) through a superior incision in each eye 15 years ago. Upon examination, BCVA is 20/25 with a manifest refraction of -1.75 +0.50 x 005º OD, and glare testing reduces visual acuity to 20/100 OD. In the left eye, BCVA is 20/30 with a manifest refraction of -3.50 +0.75 x 175º, and glare testing reduces visual acuity to 20/200. A slit-lamp examination reveals a clear and a well-centered phakic IOL in each eye (Figure). The right eye has a 1+ nuclear sclerotic cataract and a 1+ posterior subcapsular cataract. The left eye exhibits mild anterior capsular changes and has a 1+ nuclear sclerotic cataract and a 3+ posterior subcapsular cataract. A dilated fundus examination shows mild myopic degeneration but no holes, breaks, or tears. The endothelial Figure. A Verisyse phakic IOL in situ in the left eye. cell count is 2,400 cells/mm2 in the right eye and 2,000 cells/mm2 in the left. An OCT scan of the retina is normal in each eye. The patient is concerned about seeing glare at night. He expresses a desire for good midrange vision. He does not want monovision but would instead like the visual acuity in his left eye to be similar to that in his right. How would you proceed? Would you offer laser cataract surgery? Where would you place the cataract incision, and which IOL would you offer to this patient? Are you concerned about the endothelial cell count? —Case prepared by Audrey R. Talley Rostov, MD

surgery in this case because the gas lip. After exchanging the aqueous for that accumulates between the IOL and a cohesive OVD, I would use a pair of the crystalline lens could cause a radial Artiflex implantation forceps (Ophtec, anterior capsular tear. not available in the United States) to I would explant the phakic IOL grasp the haptic base and disenclavate RUPERT MENAPACE, MD, FEBO through a superior frown incision and the iris with a needle passed through then perform cataract surgery using a paracenteses at the 10 and 2 clock Iris-fixated phakic IOLs are an temporal approach under topical and positions. After enlargement of effective and safe option for correcting intracameral anesthesia. To begin the the corneal lip to 5.5 mm, the IOL myopia. Implantation of a nonfoldable explantation, after asking the patient would be rotated vertically and PMMA Verisyse lens with a 5-mm to look down, I would create a superior explanted while the endothelium was optic requires a large incision that fornix-based conjunctival flap and a protected with a spatula. can induce significant astigmatism, 4.5-mm scleral frown incision located Standard temporal-access 2.2-mm particularly when the incision is as posteriorly as possible. Next, I would posterior-limbal cataract surgery would created in clear cornea. I recommend dissect a 5.5-mm sclerocorneal tunnel follow with a related use of a dispersive against using a femtosecond laser for and create a 2.2-mm central corneal OVD during .

20 CATARACT & REFRACTIVE SURGERY TODAY | SEPTEMBER 2020 CATARACT SURGERY CASE FILES s

The choice of replacement IOL A mydriatic solution would be corneal incision. (A similar case may be depends on the quality of the patient’s administered through the 2.2-mm viewed at bit.ly/0920CRSTCSCase.) preoperative . temporal clear corneal incision created I (M.M.) would avoid choosing a Asymmetric bow tie astigmatism for disenclavation of the phakic IOL. multifocal lens for this patient because resulting from the implantation of Cataract surgery would be performed he has expressed concern about glare. I a Verisyse lens through a superior through this same incision under would use the axial length adjustment corneal incision would decrease the a cohesive OVD. I would perform recommended by Douglas D. Koch, MD, optical performance of multifocal phacoemulsification according to and the SRK/T formula. The patient and extended depth of focus IOLs. my usual technique and insert a desires midrange vision, so a standard The planned posteriorly positioned monofocal IOL into the capsular bag. one-piece monofocal IOL would be a 5.5-mm frown incision would avoid I would not suture the incision at the reasonable choice. If the white-to-white inducing additional astigmatism during conclusion of surgery. corneal diameter is larger than 12.7 mm explantation of the phakic IOL. A toric or the anterior chamber is large, I trifocal lens could be considered. An (M.M.) would prefer to implant a excimer laser enhancement might be three-piece Sensar IOL (model AR40, required to optimize the refractive Johnson & Johnson Vision). result but should not be performed To protect the endothelium, a before 6 months have elapsed in case generous amount of a dispersive OVD the cataract incision sags and induces a would be instilled after each step of the change in astigmatism.1 MAJID MOSHIRFAR, MD; cataract procedure. The preoperative AND MARGARET H. SHMUNES, BS discussion with the patient should cover the risk of further endothelial cell loss,3 This patient appears to have been his potential need for an endothelial highly myopic (> -15.50 D) given that transplant, and the cumulative risk of a this appears to be a 5.0-mm Verisyse retinal detachment.4 model 206 phakic lens. I (M.M.) would proceed with conventional cataract SIMONETTA MORSELLI, MD surgery because laser cataract surgery could pose several risks in this case. I would counsel this patient on his For example, the endothelial cell low endothelial cell counts and his count is already lower than normal; possible future need for an endothelial the average range for a man this age, cell transplant. I would offer to according to the literature,2 is 2,200 SHERI ROWEN, MD, FACS perform cataract surgery and implant to 3,500 cells/mm2. The docking of a a monofocal IOL. When performing femtosecond laser could contribute to In challenging cases such as this the IOL power calculation, I would endothelial contusion in the periphery one, it is clear that a 6-mm incision target -2.00 D to obtain the same because of the close proximity of the will be required just to extract the postoperative refraction as the right eye. phakic lens to the iris. phakic IOL. This patient obviously has The pupil would not be dilated Moreover, I (M.M.) want to create a clinically significant cataract that before surgery. After the conjunctiva a concentric . Because requires removal. I would want to know had been opened from the 11 to the of the enclavation site of the phakic the keratometry readings from before 2 clock position, a 4.5-mm scleral lens along the horizontal meridian, the and after phakic IOL surgery in order frown incision would be created at pupil probably will not dilate uniformly to determine the effect of the earlier the 12 clock position, and a 2.2-mm along that meridian. This could limit 6-mm incision. The current amount of temporal corneal sideport incision the geometric centration of a laser refractive cylinder is acceptable after would be created. Under a cohesive capsulotomy. a large superior 6-mm incision, but it OVD, the phakic IOL would be I (M.M.) would initially make a is important to determine the change disenclavated with special forceps and 5-mm self-sealing scleral frown incision over time. I would also like to see the a manipulator. After explantation of superiorly through which I would current topographic maps in order to the IOL, the scleral incision would be disenclavate, rotate, and remove assess the regularity of the cornea. closed with a 10-0 nylon suture, and the the phakic lens, but I recommend This patient’s endothelial cell count conjunctiva would be closed with an proceeding with the cataract extraction is lower than normal. I would try to 8-0 polyglactin suture (Vicryl, Ethicon). through a temporal 2.4-mm clear use a Ziemer Femto LDV femtosecond

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. 2015;159(5):877-883.e7. . 1996;10:237-240. Editorial Advisory Board Am J Ophthalmol AUDREY R. TALLEY ROSTOV, MD MD AUDREY R. TALLEY ROSTOV, Editorial Advisory Board Editorial Advisory Board CRST Europe CRST CRST Spektrum Augenheilkd . 2013;8:1445-1450. . 2014;8:711-716. Professor of Ophthalmology and Head of Day Professor of Ophthalmology and Head of Day [email protected] Financial disclosure: None Head of the Ophthalmology Department, Member, [email protected] Financial disclosure: None Medical Research Director, Hoopes Vision Center, Professor of Ophthalmology, John A. Moran Eye Private practice, Northwest Eye Surgeons, Seattle Private practice, Northwest Seattle Medical advisory board, SightLife, Member, [email protected] Financial disclosure: Consultant (Alcon, [email protected] Financial disclosure: Consultant (Alcon, Allergan, Research fellow, Hoopes Vision Center, Draper, Utah [email protected] Financial disclosure: None Financial disclosure: None Private practice, Medical Director, NVision Centers, Member, Surgery Unit, Vienna General Hospital and Surgery Unit, Vienna General Hospital and University Medical School, Vienna, Austria S. Bassiano Hospital, Bassano del Grappa, Italy Draper, Utah Center, University of Utah, Salt Lake City Bausch + Lomb, Lensar) Bausch + Lomb, Novartis, Orasis); Scientific Bausch + Lomb, Novartis, Orasis); Scientific advisory board (Orasis); Speaker’s bureau (Alcon, Allergan, Bausch + Lomb, Novartis, Orasis) Newport Beach, California       [email protected]        RUPERT MENAPACE, MD, FEBO n n n SIMONETTA MORSELLI, MD n n n n MAJID MOSHIRFAR, MD n n n n SHERI ROWEN, MD, FACS n n refraction was -1.50 D. TheD. -1.50 was refraction patient was outcome. the with pleased stable alternative C, Hirsch U, Strenn K. A simple, safe and 1. Menapace R, Vass PMMA intraocular lenses with a large to the frown incision for implantation of optic diameter. D, Stech S, Stanislovas Ašoklis R. 2. Galgauskas S, Norvydaite D, Krasauskaite and endothelial characteristics. Age-related changes in corneal thickness Interv Aging Valliammai M. Incidence rate and 3. Moshirfar M, Imbornoni LM, Ostler EM, formation and corneal decompensa occurrence of visually significant cataract phakic intraocular lens. tion after implantation of Verisyse/Artisan Ophthalmol al; META-analysis for Pathologic Myopia4. Ohno-Matsui K, Kawasaki R, Jonas JB, et classification and grading(META-PM) Study Group. International photographic system for myopic maculopathy. SECTION EDITOR n n n n n n MARGARET H. SHMUNES, BS n n n n

BIT.LY/0920CRSTCSCASE2 ROSTOV, MD ROSTOV, MD WATCH IT NOW

WHAT I DID: AUDREY R. TALLEY WHAT I DID: AUDREY R. TALLEY s After hydrodelineation andhydrodelineation After I decided to perform laser cataractlaser perform to decided I I would expect this patient to doto patient this expect would I and aspiration using a low infusionlow a using aspiration and lensSofPort three-piece pressure.A wasLomb) + Bausch LI61AO, (model postoperativetargeted the implanted; then created a 6-mm temporal incision,temporal 6-mm a created then (Viscoat,OVD dispersive a injected disenclavatedVision), Johnson & Johnson enclavationan with lens Verisyse the IOL.the explanted and needle, fragmentedthe hydrodissectionof removedeasily were pieces the cataract, modifieda of part as irrigation with cataract small-incision of technique inplaced were sutures Two surgery. cortexthe and incision, temporal the irrigation bimanual with removed was surgery using the Lensar Laser SystemLaser Lensar the using surgery minimizeto effort an in (Lensar) laserThe loss. cell endothelial phacofragmentationand capsulotomy I complication. without executed were 4.00 D) will most likely provide theprovide likely most will D) 4.00 patientthis acuity visual intermediate visualdistance good as well as desires Ifnight. at glare minimizing while acuity mm,26 than greater is length axial the formula Wang-Koch the use would I formula. 1 Holladay the and adjustment well. very | SEPTEMBER 2020

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CATARACT SURGERY CATARACT 22 s