Common ICD-10 Codes for Flow Cytometry Cancer Testing Local Coverage Determination Flow Cytometry ID L35032
Complete the 5-digit Lymphoma codes with a 5th digit Complete the 5-digit Leukemia/Myeloma codes with a 5th digit Unspecified site ...... 0 Not having achieved remission ...... 0 Lymph nodes of head, face and neck ...... 1 In remission ...... 1 Intrathoracic lymph nodes ...... 2 In relapse ...... 2 Intra-abdominal lymph nodes ...... 3 Lymph nodes of axilla and upper limb ...... 4 Multiple myeloma and malignant plasma cell neoplasms Lymph nodes of inguinal region and lower limb ...... 5 Multiple myeloma ...... C90.0_ Intrapelvic lymph nodes ...... 6 Plasma cell leukemia ...... C90.1_ Spleen ...... 7 Extramedullary plasmacytoma ...... C90.2_ Lymph nodes of multiple sites ...... 8 Solitary plasmacytoma ...... C90.3_ Extranodal and solid organ sites ...... 9 Lymphoid leukemia Hodgkin lymphoma Acute lymphoblastic leukemia [ALL] ...... C91.0_ Nodular lymphocyte predominant Hodgkin lymphoma ...... C81.0_ Chronic lymphocytic leukemia of B-cell type ...... C91.1_ Nodular sclerosis Hodgkin lymphoma ...... C81.1_ Prolymphocytic leukemia of B-cell type ...... C91.3_ Mixed cellularity Hodgkin lymphoma ...... C81.2_ Hairy cell leukemia ...... C91.4_ Lymphocyte depleted Hodgkin lymphoma ...... C81.3_ Adult T-cell lymphoma/leukemia (HTLV-1-associated) ...... C91.5_ Lymphocyte-rich Hodgkin lymphoma ...... C81.4_ Prolymphocytic leukemia of T-cell type...... C91.6_ Other Hodgkin lymphoma ...... C81.7_ Lymphoid leukemia, unspecified ...... C91.9_ Hodgkin lymphoma, unspecified ...... C81.9_ Mature B-cell leukemia Burkitt-type ...... C91.A_ Other lymphoid leukemia ...... C91.Z_ Follicular lymphoma Follicular lymphoma grade I ...... C82.0_ Myeloid leukemia Follicular lymphoma grade II ...... C82.1_ Acute myeloblastic leukemia ...... C92.0_ Follicular lymphoma grade III, unspecified ...... C82.2_ Chronic myeloid leukemia, BCR/ABL-positive ...... C92.1_ Follicular lymphoma grade IIIa ...... C82.3_ Atypical chronic myeloid leukemia, BCR/ABL-negative ...... C92.2_ Follicular lymphoma grade IIIb ...... C82.4_ Myeloid sarcoma ...... C92.3_ Diffuse follicle center lymphoma...... C82.5_ Acute promyelocytic leukemia ...... C92.4_ Cutaneous follicle center lymphoma ...... C82.6_ Acute myelomonocytic leukemia ...... C92.5_ Other types of follicular lymphoma ...... C82.8_ Acute myeloid leukemia with 11q23-abnormality ...... C92.6_ Follicular lymphoma, unspecified ...... C82.9_ Myeloid leukemia, unspecified ...... C92.9_ Acute myeloid leukemia with multilineage dysplasia ...... C92.A_ Non-follicular lymphoma Other myeloid leukemia ...... C92.Z_ Small cell B-cell lymphoma ...... C83.0_ Mantle cell lymphoma ...... C83.1_ Monocytic leukemia Diffuse large B-cell lymphoma ...... C83.3_ Acute monoblastic/monocytic leukemia ...... C93.0_ Lymphoblastic (diffuse) lymphoma ...... C83.5_ Chronic myelomonocytic leukemia ...... C93.1_ Burkitt lymphoma...... C83.7_ Juvenile myelomonocytic leukemia ...... C93.3_ Other non-follicular lymphoma...... C83.8_ Monocytic leukemia, unspecified ...... C93.9_ Non-follicular (diffuse) lymphoma, unspecified...... C83.9_ Other monocytic leukemia ...... C93.Z_
Mature T/NK-cell lymphomas Other leukemias of specified cell type Mycosis fungoides ...... C84.0_ Acute erythroid leukemia ...... C94.0_ Sézary disease ...... C84.1_ Acute megakaryoblastic leukemia ...... C94.2_ Peripheral T-cell lymphoma, not classified ...... C84.4_ Mast cell leukemia ...... C94.3_ Anaplastic large cell lymphoma, ALK-positive ...... C84.6_ Acute panmyelosis with myelofibrosis ...... C94.4_ Anaplastic large cell lymphoma, ALK-negative ...... C84.7_ Myelodysplastic disease, not classified ...... C94.6 Mature T/NK-cell lymphomas, unspecified ...... C84.9_ Other specified leukemias...... C94.8_ Cutaneous T-cell lymphoma, unspecified ...... C84.A_ Other mature T/NK-cell lymphomas ...... C84.Z_ Leukemia of unspecified cell type Acute leukemia of unspecified cell type ...... C95.0_ Other specified and unspecified types of non-Hodgkin lymphoma Chronic leukemia of unspecified cell type ...... C95.1_ Unspecified B-cell lymphoma ...... C85.1_ Leukemia, unspecified...... C95.9_ Mediastinal (thymic) large B-cell lymphoma ...... C85.2_ Other specified types of non-Hodgkin lymphoma ...... C85.8_ Other and unspecified malignant neoplasms of lymphoid, Non-Hodgkin lymphoma, unspecified...... C85.9_ hematopoietic and related tissue Multifocal and multisystemic (disseminated) Langerhans-cell Malignant immunoproliferative diseases and certain other histiocytosis ...... C96.0 B-cell lymphomas Malignant mast cell neoplasm, unspecified ...... C96.20 Waldenström macroglobulinemia ...... C88.0 Mast cell sarcoma ...... C96.22 Extranodal marginal zone B-cell lymphoma of mucosa-associated Other malignant mast cell neoplasm ...... C96.29 lymphoid tissue [MALT-lymphoma] ...... C88.4 Sarcoma of dendritic cells (accessory cells) ...... C96.4 Malignant neoplasm of ovary Other and unspecified anemias Malignant neoplasm of right ovary ...... C56.1 Anemia in neoplastic disease ...... D63.0 Malignant neoplasm of left ovary ...... C56.2 Hereditary sidertoblastic anemia ...... D64.0 Malignant neoplasm of unspecified ovary ...... C56.9 Congenital dyserythropoietic anemia ...... D64.4 Other specified anemias ...... D64.89 Malignant neoplasm of breast of unspecified site Anemia, unspecified ...... D64.9 Unspecified site of right female breast ...... C50.911 Unspecified site of left female breast ...... C50.912 Purpura and other hemorrhagic conditions Unspecified site of unspecified female breast ...... C50.919 Immune thrombocytopenic purpura ...... D69.3 Unspecified site of right male breast ...... C50.921 Evans syndrome ...... D69.41 Unspecified site of left male breast...... C50.922 Congenital and hereditary thrombocytopenia purpura ...... D69.42 Unspecified site of unspecified male breast ...... C50.929 Other primary thrombocytopenia ...... D69.49 Thrombocytopenia, unspecified ...... D69.6 Chronic myeloproliferative neoplasms Polycythemia vera ...... D45 Acquired pure red cell aplasia [erythroblastopenia] Essential (hemorrhagic) thrombocythemia ...... D47.3 Chronic acquired pure red cell aplasia ...... D60.0 Myelofibrosis ...... D75.81 Transient acquired pure red cell aplasia ...... D60.1 Chronic myeloid leukemia, BCR/ABL-positive (see front for 5th digit).. C92.1_ Other acquired pure red cell aplasias ...... D60.8 Other specified neoplasms of uncertain behavior of lymphoid, Acquired pure red cell aplasia, unspecified ...... D60.9 hematopoietic and related tissue ...... D47.Z9 Neutropenia and other disorders of white blood cells Myelodysplastic syndromes Congenital agranulocytosis ...... D70.0 Refractory anemia without ring sideroblasts, so stated ...... D46.0 Agranulocytosis secondary to cancer chemotherapy ...... D70.1 Refractory anemia with ring sideroblasts ...... D46.1 Other drug-induced agranulocytosis ...... D70.2 Refractory anemia with excess of blasts, unspecified ...... D46.20 Neutropenia due to infection ...... D70.3 Refractory anemia with excess of blasts (RAEB)-1 ...... D46.21 Cyclic neutropenia ...... D70.4 Refractory anemia with excess of blasts (RAEB)-2 ...... D46.22 Other neutropenia ...... D70.8 Refractory anemia, unspecified ...... D46.4 Neutropenia, unspecified...... D70.9 Myelodysplastic syndrome, unspecified ...... D46.9 Functional disorders of polymorphonuclear neutrophils ...... D71 Refractory cytopenia with multilineage dysplasia ...... D46.A Genetic anomalies of leukocytes ...... D72.0 Refractory cytopenia with multilineage dysplasia and Eosinophilia ...... D72.1 ring sideroblasts ...... D46.B Lymphocytopenia ...... D72.810 Myelodysplastic syndrome with isolated del(5q) Other decreased white blood cell count ...... D72.818 chromosomal abnormality ...... D46.C Decreased white blood cell count, unspecified ...... D72.819 Other myelodysplastic syndromes ...... D46.Z Lymphocytosis (symptomatic) ...... D72.820 Chronic myeloproliferative disease ...... D47.1 Monocytosis (symptomatic) ...... D72.821 Neoplasm of uncertain behavior of lymphoid, hematopoietic and Plasmacytosis ...... D72.822 related tissue, unspecified...... D47.9 Leukemoid reaction ...... D72.823 Post-transplant lymphoproliferative disorder (PTLD) ...... D47.Z1 Basophilia ...... D72.824 Other specified neoplasms of uncertain behavior of lymphoid, Other elevated white blood cell count ...... D72.828 hematopoietic and related tissue...... D47.Z9 Elevated white blood cell count, unspecified ...... D72.829 Other specified disorders of white blood cells ...... D72.89 Disorders of plasma protein metabolism Disorder of white blood cells, unspecified ...... D72.9 Monoclonal gammopathy ...... D47.2 Cryoglobulinemia ...... D89.1 Sickle-cell disorders Hypergammaglobulinemia, unspecified ...... D89.2 Hb-SS disease with splenic sequestration ...... D57.02 Waldenström macroglobulinemia ...... C88.0 Sickle-cell/Hb-C disease with splenic sequestration ...... D57.212 Other disorders of plasma-protein metabolism, not elsewhere classified. E88.09 Sickle-cell thalassemia with splenic sequestration ...... D57.412 Other hemoglobinopathies ...... D58.2 Other aplastic anemias and other bone marrow failure syndromes Other and unspecified diseases of blood and Drug-induced aplastic anemia ...... D61.1 blood-forming organs Aplastic anemia due to other external agents ...... D61.2 Myelofibrosis ...... D75.81 Idiopathic aplastic anemia ...... D61.3 Disease of blood and blood-forming organs, unspecified ...... D75.9 Antineoplastic chemotherapy induced pancytopenia ...... D61.810 Other drug-induced pancytopenia ...... D61.811 Symptoms, signs and abnormal clinical and laboratory findings, Other pancytopenia ...... D61.818 not elsewhere classified Myelophthisis ...... D61.82 Splenomegaly, not elsewhere classified...... R16.1 Other specified aplastic anemias and other bone marrow Localized enlarged lymph nodes ...... R59.0 failure syndromes ...... D61.89 Generalized enlarged lymph nodes ...... R59.1 Aplastic anemia, unspecified ...... D61.9 Enlarged lymph nodes, unspecified ...... R59.9
This list is subject to change and is not all-inclusive. CP–FY–0010–v1–1217
Please refer to the most current version of the Coding Manual of the American Medical Association (AMA) for a complete list of ICD-10 codes. Information has been obtained through the Centers for Medicare and Medicaid Services (CMS) and Local Coverage Determination for Flow Cytometry. Codes listed are effective as of October 1, 2017.