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Graduation 2013. Wednesday 17 July 2013 the University of Sheffield
Graduation 2013. Wednesday 17 July 2013 The University of Sheffield Your graduation day is a special day for you and your family, a day for celebrating your achievements and looking forward to a bright future. As a graduate of the University of Sheffield you have every reason to be proud. You are joining a long tradition of excellence stretching back more than 100 years. The University of Sheffield was founded with the amalgamation of the School of Medicine, Sheffield Technical School and Firth College. In 1905, we received a Royal Charter and Firth Court was officially opened by King Edward VII and Queen Alexandra. At that time, there were 363 students reading for degrees in arts, pure science, medicine and applied science. By the time of our centenary, there were over 25,000 students from more than 100 countries, across 70 academic departments. Today, a degree from Sheffield is recognised all over the world as a hallmark of academic excellence. We are proud of our graduates and we are confident that you will make a difference wherever you choose to build your future. With every generation of graduates, our university goes from strength to strength. This is the original fundraising poster from 1904/1905 which helped raise donations for the University of Sheffield. Over £50,000 (worth more than £15 million today) was donated by steelworkers, coal miners, factory workers and the people of Sheffield in penny donations to help found the University. A century on, the University is now rated as one of the top world universities – according to the Shanghai Jiao Tong Academic Ranking of World Universities. -
Academic Career Research Interests Honors and Awards
Prof. Dr. Christian P.R. Hackenberger born 04.02.1976 in Osnabrück Humboldt Universität zu Berlin Leibniz‐Forschungsinstitut für Molekulare Pharmakologie (FMP) Homepage: www.fmp‐berlin.info/hackenbe/ Academic career 1996 – 1998 Undergraduate studies and prediploma in Chemistry Albert‐Ludwigs‐Universität Freiburg 1998 – 1999 Graduate studies and M.Sc. with Prof. Samuel H. Gellman Univ. of Wisconsin/Madison, USA 2000 – 2003 Ph.D. research with Prof. Carsten Bolm (summa cum laude) RWTH‐Aachen 2003 – 2005 Postdoctoral work with Prof. Barbara Imperiali Massachusetts Institute of Technology, USA 2004 Research stay with Prof. Sheena E. Radford University of Leeds, UK 2005 – 2006 Junior group leader as Liebig‐Scholar (FCI) Freie Universität Berlin 2006 – 2011 Emmy‐Noether‐Group leader (DFG) Freie Universität Berlin 2011 Habilitation and venia legendi in Organic Chemistry Freie Universität Berlin 2011 – 2012 Associate Professor (W2) for Bioorganic Chemistry Freie Universität Berlin 2012 – Leibniz‐Humboldt‐Professor (W3) for Chemical Biology Humboldt Universität zu Berlin and FMP Research interests ‐ Development of ligation and modification strategies for the synthesis of functional proteins ‐ Labeling strategies for antibody‐ and nanobody‐conjugates, generation of antibody‐drug‐conjugates (ADCs) ‐ Synthesis and proteomic analysis of labile phosphorylated peptides (pLys and pCys) ‐ Intracellular delivery and targeting of functional proteins ‐ Functional investigation of the Alzheimer‐relevant Tau protein ‐ Engineering of protein‐based multivalent scaffolds, metabolic oligosaccharide engineering Honors and Awards 2018 Leonidas Zervas Award of the European Peptide Society 2018 Leibniz Gründerpreis for the foundation of Tubulis Technologies 2016 Fellow of the Royal Society of Chemistry 2014 “The best 40 under 40 in Germany” (Welt am Sonntag) 2013 Harlan L. -
Caged Phosphopeptides and Phosphoproteins: Agents in Unraveling Complex Biological Pathways
Caged Phosphopeptides and Phosphoproteins: Agents in Unraveling Complex Biological Pathways by Deborah Maria Rothman S. B., Biochemistry, University of Chicago, 2000 A. B., Biology, University of Chicago, 2000 Submitted to the Department of Chemistry in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy at the Massachusetts Institute of Technology June 2005 MASSACi.USE_.]S iNSTITTE OF TECHNOLOGY © 2005 Massachusetts Institute of Technology JUN 2 1 2005 All rights reserved LIBRARIES Signature of Author: ( I I 1., , ,, - Department of Chemistry May 9, 2005 Certified by: Barbara Imperiali Class of 1922 Professor of Chemistry and Professor of Biology Thesis Supervisor Accepted by: Robert W. Field Haslam and Dewey Professor of Chemistry Chairman, Departmental Committee on Graduate Students AtmCHlvtS This doctoral thesis has been examined by a committee of the Department of Chemistry as follows: Timothy F. Jamison Chairman Professor of Chemistry 6) Barbara ImDerialiI Thesis Supervisor Class of 1922 Professor of Chemistry and Professor of Biology Douglas A. Lauffenburger oafEr fi s o ei/- g/ a Bl Whitaker Professor of Biological Engineering, Pofessor of themica/ngineering and Biology 2 Caged Phosphopeptides and Phosphoproteins: Agents in Unraveling Complex Biological Pathways by Deborah Maria Rothman Submitted to the Department of Chemistry on May 9, 2005 in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy ABSTRACT Within cellular signaling, protein phosphorylation is the post-translational modification most frequently used to regulate protein activity. Protein kinases and phosphoprotein phosphatases generate and terminate these phosphoryl signals, respectively. Chemical approaches for studying protein phosphorylation and the roles of phosphoproteins include photolabile caged analogs of bioactive species. -
Bacterial Carbohydrate Diversity — a Brave New World 1,2
Available online at www.sciencedirect.com ScienceDirect Bacterial carbohydrate diversity — a Brave New World 1,2 Barbara Imperiali Glycans and glycoconjugates feature on the ‘front line’ of (Figure 1a) and among these, the hexoses show extensive bacterial cells, playing critical roles in the mechanical and variation in substitution patterns and the heptoses and chemical stability of the microorganisms, and orchestrating octoses are exclusively prokaryotic. The nonulosonic acids, interactions with the environment and all other living organisms. which are derived biosynthetically from the hexoses, are To negotiate such central tasks, bacterial glycomes also far more varied: there is a single example in man, but incorporate a dizzying array of carbohydrate building blocks dozens have been characterized to date in various bacteria and non-carbohydrate modifications, which create [5]. In addition, a plethora of modifications including alkyl, opportunities for infinite structural variation. This review acyl, amino acyl, phosphoryl, and even nucleoside groups highlights some of the challenges and opportunities for the are often found decorating the carbohydrates [4 ]. Defining chemical biology community in the field of bacterial and cataloging this variety, not to mention understanding glycobiology. its significance, is a Herculean task. Addresses Bacterial carbohydrates may be components of repeating 1 Department of Biology, Massachusetts Institute of Technology, glycopolymers or, more complex glycoconjugates, which Cambridge, MA 02139, United States 2 may reveal elaborate ‘samplers’ of different sugars Department of Chemistry, Massachusetts Institute of Technology, (Figure 1b) [6]. In cells, the glycans commonly include Cambridge, MA 02139, United States cell-surface structures that are essential for the mechanical Corresponding author: Imperiali, Barbara ([email protected]) integrity of bacterial cells and for critical interactions with other bacteria and the hosts with which they coexist [7,8]. -
Nobel Special Issue of Chemical Physics Letters
Accepted Manuscript Editorial Nobel Special Issue of Chemical Physics Letters David Clary, Mitchio Okumura, Villy Sundstrom PII: S0009-2614(13)01325-0 DOI: http://dx.doi.org/10.1016/j.cplett.2013.10.045 Reference: CPLETT 31683 To appear in: Chemical Physics Letters Please cite this article as: D. Clary, M. Okumura, V. Sundstrom, Nobel Special Issue of Chemical Physics Letters, Chemical Physics Letters (2013), doi: http://dx.doi.org/10.1016/j.cplett.2013.10.045 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. Nobel Special Issue of Chemical Physics Letters Editorial The hallmark of Chemical Physics Letters is the fast publication of urgent communications of the highest quality. It has not escaped our notice that this policy has allowed several of the breakthrough papers in chemistry to be published in our journal. Indeed, looking through Chemical Physics Letters over the last 42 years we found papers published by as many as 15 authors who went on subsequently to win the Nobel Prize in Chemistry for work linked to their articles. Furthermore, several of these papers were referenced in the Nobel citations. We thought our readers would find it of interest to see a collection of these papers brought together and introduced with summaries explaining their significance and written by the Nobelists themselves, close colleagues or editors of the journal. -
Jerry M. Troutman, 06/28/2015 1
Jerry M. Troutman, 06/28/2015 1 Jerry M. Troutman University of North Carolina at Charlotte 9201 University City Blvd. Burson 262 Charlotte, NC 28223 Tel: (704) 687-5180 E-mail: [email protected] Website: https://clas-chemistry.uncc.edu/jerry-troutman-research/ EDUCATION University of Kentucky Medical Center, Lexington, KY 09/2006 Ph.D. Biochemistry East Carolina University, Greenville, NC 05/2000 B.S. Biochemistry/Chemistry/Philosophy Cum Laude 2000 PROFESSIONAL Assistant Professor 08/2010-present University of North Carolina at Charlotte, Department of Chemistry NIH Postdoctoral Fellow 09/2008-08/2010 Massachusetts Institute of Technology, Department of Chemistry Advisor: Class of 1922 professor of Chemistry and Biology Barbara Imperiali Postdoctoral Associate 09/2006-09/2008 Massachusetts Institute of Technology, Department of Chemistry Advisor: Class of 1922 Professor of Chemistry and Biology Barbara Imperiali Investigation of bacterial N-linked glycosylation pathways Graduate Research Assistant 08/2000-09/2006 University of Kentucky Medical Center, Department of Molecular and Cellular Biochemistry Advisor: Associate Professor Hans P. Spielmann Isoprenoid selectivity of protein farnesyl transferase a key anti-cancer target HONORS Ruth L. Kirschstein National Research Service Award. 2008-2010 National Institutes of Health General Medicine. (Post-doc, MIT) Research Challenge Trust Fellowship. (Graduate Student, UK) 2001-2002 University Book Exchange Outstanding Senior Scholarship 1999 (Undergraduate, ECU) PROFESSIONAL MEMBERSHIPS -
Miller Fellow Focus
The Adolph C. and Mary Sprague Newsletter MILLER INSTITUTE Fall 2016 for Basic Research in Science Understanding Dark Energy and Neutrinos Inside this edition: from the South Pole Miller Fellow Focus 1-3 From the Executive Director 4 Miller Fellow Focus: Tijmen de Haan Call for Nominations 5 odern cosmology provides an 6 Mincredibly powerful description In the News of the universe we live in. The stan- 20th Annual Symposium 7 dard model of Big Bang cosmology 8 takes only a few assumptions about Next Steps & Birth Announcements the physical laws and initial condi- tions, and makes a wealth of predic- Call for Nominations: tions. As our techniques for measur- ing the large-scale properties of the Miller Research Fellowship universe improve, the observations are found to be consistent with the Nominations predictions of the standard model Deadline: Saturday, September 10, 2016 of Big Bang cosmology time and time again. However, several open ques- Miller Research Professorship tions remain. Applications e can also use our measure- Deadline: Thursday, September 15, 2016 n the late 1990s, we learned that the Wments of the expansion rate Iexpansion of the universe is current- and growth of structure in the uni- Visiting Miller Professorship ly accelerating. This is due to a mysteri- verse to determine the properties of Departmental Nominations ous type of energy cosmologists have its contents. Around the turn of the Deadline: Friday, September 16, 2016 termed dark energy. This discovery millenium, neutrinos, long thought to led to the 2011 Nobel Prize in Phys- be massless particles, were found to See page 5 for more details. -
2010 Newsletter
UCL DEPARTMENT OF CHEMISTRY Welcome to ChemUCL! It is a pleasure for me to introduce the 2010 newsletter. I hope it has been a productive and enjoyable year for all of you. I have taken over as head of department from Professor Steve Caddick as of the 1st of May. I am sure you would like to join with me in thanking Steve for his work as head of department for the past two and half years. Steve will still continue his research in the department but has taken over as UCL Vice Provost for Enterprise. There are lots of exciting updates in the following pages that cover every aspects of the life in the department. In particular at the time of writing our new intake for both undergraduates (120+) and postgraduates (60+) is signifi cantly above anything the department has managed to achieve in the last thirty years. The quality of the students is again suitably impressive with for example, the fi rst 70 undergraduates getting as a minimum AAA at A-level. Furthermore there is a veritable forest of the new A* A-level grades across the intake. The department has also undergone a face lift over the last month with the front entrance being completely remodelled, including a new full glass fronted entrance, new card access and, although not quite to my taste, a very vivid colour scheme. I look forward to seeing many of you at the Lab Dinner. Best wishes Ivan P. Parkin, Head of Department LAB DINNER 2010 Th e annual Lab Dinner will be held in the Old Refectory on Friday 26th November 2010 Th e provisional programme is as follows: 16.00 Afternoon tea in the Nyholm Room 17.00 Pre-dinner lecture by Dr Andrea Sella, Ramsay Lecture Th eatre 18.15 Pre-dinner drinks in the North Cloisters 19.15 Dinner in the Old Refectory, speaker: Prof. -
View Elizabeth Komives' Curriculum Vitae
CURRICULUM VITAE ELIZABETH A. KOMIVES Department of Chemistry and Biochemistry University of California, San Diego, La Jolla, CA 92093-0378 Telephone: (858) 534-3058, FAX: (858) 534-6174 email: [email protected], webpage: http://chem-faculty.ucsd.edu/komives/ Employment UNIVERSITY OF CALIFORNIA SAN DIEGO Assistant Professor of Chemistry and Biochemistry, 1990 - 1996 Associate Professor of Chemistry and Biochemistry, 1996 - 2000 Professor of Chemistry and Biochemistry, 2000 - present Education MASSACHUSETTS INSTITUTE OF TECHNOLOGY M.S. in Toxicology, B.S. in Chemistry, 1982 UNIVERSITY OF CALIFORNIA SAN FRANCISCO Ph.D. in Pharmaceutical Chemistry with Paul R. Ortiz de Montellano 1982 - 1987 Research Topic: The Mechanism of π-Bond Oxidation by Cytochrome P-450 HARVARD UNIVERSITY NIH Postdoctoral Fellow with Jeremy R. Knowles 1987 - 1990 Research Topics: Analysis of Triosephosphate Isomerase Mutants using FTIR and X-ray crystallography Academic Honors Regents Fellowship (1982 - 1983) Graduate Opportunity Fellowship (1983 - 1984) NIH Graduate Traineeship (1984 - 1986) NIH Postdoctoral Traineeship (1987 - 1989) Long Award for Excellence in Teaching (1983) Rita Allen Scholar (1991 - 1996) Searle Scholar (1992 - 1995) Kaiser Award for Excellence in Teaching, First Year Medical Students (1999) Brown and Williamson Scholar, University of Louisville (2000) Barany Award for Outstanding Contributions to Biophysics, Biophysical Society (2000) Nominating Committee, Protein Society (2001-2004) Council, Biophysical Society (2002-2005) Current Research -
ICBS 2018 Vancouver, Canada
7th Annual Conference September 24-27, 2018 ICBS 2018 Vancouver, Canada Scientific Program Towards Translational Impact www.chemical-biology.org 7th Annual Conference | September 24-27, 2018 | Vancouver, Canada Acknowledgements Towards Translational Impact September 24th – 27th, 2018 | Vancouver, BC Local Program and Organizing Committee Tom Pfeifer, Centre for Drug Research and Development Roger Linington, Simon Fraser University Michel Roberge, University of British Columbia Nicolette Honson, Centre for Drug Research and Development ICBS Organizing Committee Haian Fu, Chair, Emory University, USA Lixin Zhang, ECUST, China Sally-Ann Poulsen, Griffith University, Australia Jonathan Baell, Monash University, Australia Mahabir Gupta, University of Panama, Panama Junying Yuan, Harvard Medical School, USA Masatoshi Hagiwara, Kyoto University, Japan Petr Bartunek, CZ-OPENSCREEN and Institute of Molecular Jason Micklefield, The University of Manchester, UK Genetics, Czech Republic Siddhartha Roy, Boss Institute, India ICBS Young Chemical Biologist Award 2018 Selection Committee Yimon Aye, Cornell University, USA Christian Ottmann, Technische Universiteit Eindhoven, Ratmir Derda, University of Alberta, Canada Netherlands Evripidis Gavathiotis, Albert Einstein College of Medicine, USA William Pomerantz, University of Minnesota, USA Kenjiro Hanaoka, University of Tokyo, Japan Qi Zhang, Fudan University, China Recording of sessions (oral or poster) by audio, video, or still photography is strictly prohibited except with the advance permission of -
Angela N. Koehler
Angela N. Koehler Koch Institute for Integrative Cancer Research at MIT Office: 617-324-7631 Department of Biological Engineering, MIT Email: [email protected] 76-361C Website: http://koehlerlab.org 77 Massachusetts Avenue Cambridge, MA 02139 Education Ph.D. Chemistry, Harvard University 2003 B.A. Biochemistry and Molecular Biology, Reed College 1997 Professional Appointments Associate Professor, Department of Biological Engineering, MIT 2019-present Institute Member, Broad Institute of MIT and Harvard 2019-present Founding Member, MIT Center for Precision Cancer Medicine 2018-present Goldblith Career Development Professor in Applied Biology 2018-2021 Intramural Faculty, Koch Institute for Integrative Cancer Research at MIT 2014-present Assistant Professor, Department of Biological Engineering, MIT 2014-2018 Karl Van Tassel (1925) Career Development Professor 2014-2017 Director, Transcriptional Chemical Biology, Chemical Biology Program, Broad Institute 2010-2013 Project & Center Manager, Broad NCI Cancer Target Discovery and Development (CTD2) Center Institute Fellow, Chemical Biology Program, Broad Institute 2003-2009 Director, Ligand Discovery, NCI Initiative for Chemical Genetics (ICG) at Harvard Research Training Graduate Student, Department of Chemistry and Chemical Biology, Harvard University 1998-2003 Laboratory of Professor Stuart L. Schreiber Committee: Professors Eric. N. Jacobsen, David R. Liu Thesis: Small molecule microarrays: A high-throughput tool for discovering protein-small molecule interactions Researcher, Department -
Contributions of Civilizations to International Prizes
CONTRIBUTIONS OF CIVILIZATIONS TO INTERNATIONAL PRIZES Split of Nobel prizes and Fields medals by civilization : PHYSICS .......................................................................................................................................................................... 1 CHEMISTRY .................................................................................................................................................................... 2 PHYSIOLOGY / MEDECINE .............................................................................................................................................. 3 LITERATURE ................................................................................................................................................................... 4 ECONOMY ...................................................................................................................................................................... 5 MATHEMATICS (Fields) .................................................................................................................................................. 5 PHYSICS Occidental / Judeo-christian (198) Alekseï Abrikossov / Zhores Alferov / Hannes Alfvén / Eric Allin Cornell / Luis Walter Alvarez / Carl David Anderson / Philip Warren Anderson / EdWard Victor Appleton / ArthUr Ashkin / John Bardeen / Barry C. Barish / Nikolay Basov / Henri BecqUerel / Johannes Georg Bednorz / Hans Bethe / Gerd Binnig / Patrick Blackett / Felix Bloch / Nicolaas Bloembergen