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Rabbit Anti-DBNDD2/CK1BP antibody

SL14203R

Product Name: DBNDD2/CK1BP Chinese Name: 酪蛋白激酶1Binding protein抗体 C20orf35; Casein kinase-1 binding protein; CK1BP; DBND2_HUMAN; Dbndd2; Alias: Dysbindin (dystrobrevin binding protein 1) domain containing 2; Dysbindin domain- containing protein 2; HSMNP1; SCF apoptosis response protein 1. Organism Species: Rabbit Clonality: Polyclonal React Species: Human, WB=1:500-2000ELISA=1:500-1000IHC-P=1:400-800IHC-F=1:400-800ICC=1:100- 500IF=1:100-500（Paraffin sections need antigen repair） Applications: not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. Molecular weight: 28kDa Cellular localization: The nucleuscytoplasmic Form: Lyophilized or Liquid Concentration: 1mg/ml KLH conjugated synthetic peptide derived from human DBNDD2/CK1BP:151- immunogen: 259/259www.sunlongbiotech.com Lsotype: IgG Purification: affinity purified by Protein A Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year Storage: when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. PubMed: PubMed CK1BP is a 261 amino acid member of the dysbindin family and is a paralog of dysbindin, a protein trafficking protein involved in lysosome biosynthesis that has been Product Detail: associated with schizophrenia and muscular dystrophy. Human and rat HSMNP1 share 86% identity and both proteins contain three casein kinase II and PKC (protein kinase C) phosphorylation sites, a putative N-glycosylation site and a PEST motif at the C- terminus. HSMNP1 is a cytoplasmic protein and it specifically localizes to vesicles during the induction of apoptosis. In addition, HSMNP1 may be involved in normal as well as pathological myeloid development. Two isoforms of HSMNP1 exist due to alternative splicing events.

Function: May modulate the activity of casein kinase-1. Inhibits CSNK1D autophosphorylation (in vitro).

Tissue Specificity: Detected in brain.

Similarity: Belongs to the dysbindin family.

SWISS: Q9BQY9

Gene ID: 55861

Database links:

Entrez Gene: 55861 Human

Omim: 611453 Human

SwissProt: Q9BQY9 Human

Unigene: 655055 Human

Importantwww.sunlongbiotech.com Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.