MEDIA201 INFORMATION 8

Cold Spring Harbor Laboratory Press About

Cold Spring Harbor Laboratory Cold Spring Harbor Laboratory Press

Founded in 1890, Cold Spring Harbor Laboratory (CSHL) has shaped Cold Spring Harbor Laboratory Press is so much more than a contemporary biomedical research and education with programs in publishing house. The publications of CSHL Press are used and valued cancer, neuroscience, plant biology, and quantitative biology. CSHL throughout the world, a reminder that the Laboratory has a special is ranked number 1 in the world by Thomson Reuters for impact of its place in the landscape of international science. Nowhere else combines research in molecular biology and genetics. The Laboratory, a private, research excellence with professional education of the nature and not-for-profit institution, has been home to eight Nobel Prize winners. quality that Cold Spring Harbor offers. CSHL Press research and review Today, CSHL’s multidisciplinary scientific community is more than 600 journals, handbooks, manuals, monographs, histories, biographies, and scientists strong and its Meetings & Courses program hosts more textbooks are a vital part of the manner through which the Laboratory than 12,500 scientists from around the world each year to its Long connects with the worldwide scientific community. Island campus and its China center. Tens of thousands more benefit The assortment of journals published by CSHL Press covers the from the research, reviews, and ideas published in journals and books complete spectrum of biological sciences. Whether your aim is to distributed internationally by CSHL Press. introduce new products, reinforce the utility of existing products, CSHL is organized into six educational divisions: Research, the Watson announce a meeting, or fill a position, our publications ensure that School of Biological Sciences, Meetings & Courses, the Banbury your message is reaching a broad forum of scientists in top-notch Center, the DNA Learning Centers, and CSHL Press. universities, pharmaceutical companies, and research institutes.

Contents Global Reach & Purchasing Power------1 Online Advertising------5 Online Rates------9 Research Journals------2 E-Mail Alerts------6 Preferred Packages------10 Review Journals------3 Additional Opportunities------7 Advertising Specifications: Print & Online------11 Methods & Resources------4 Print Rates------8 Bonus Distribution------12 Global Reach & PURCHASING POWER

Occupations Purchasing Power

Biochemistry 74% Bioinformatics 40% 85% 3% • Lab or Institutional Director 12% Other Biophysics 21% • Researcher • Principal Investigator • Postdoc Biotechnology 37% • Senior Scientist

Cancer Biology 25%

Cell Biology 55%

Developmental Biology 23%

Drug Discovery 15% Geographic Breakdown

Epigenetics 35% North America Europe Evolutionary Biology 30% Genomics 100% 49% 29% Immunology 15%

Microbiology 30%

Molecular Biology 89%

Proteomics 30%

RNAi and Gene Expression 54%

Structural Biology 27% ROW Systems Biology 20% 22%

1 Research JOURNALS

Genes & Development Genome Research RNA Learning & Memory www.genesdev.org www.genome.org www.rnajournal.org www.learnmem.org • Bimonthly publication • Monthly publication • Monthly publication • Monthly online publication • First in developmental biology • Among the top 10 of all • In the top 4% of all • In the top 20% of all journals primary research journals journals in biochemistry scientific journals in the field of neuroscience • In the top 10 of all research and molecular biology • Official journal of the journals in all sciences • Ranked third among all RNA Society Impact Factor: 2.894* genetics and genomics • Learning Impact Factor: 9.413* primary research journals Impact Factor: 4.605* • Memory • Behavior • Molecular biology • Ranked second in • Molecular biology • Cognition • Cancer and disease models biotechnology • Cell biology • Computation • Stem cells • Biochemistry • Neuroanatomy • Metabolism • RNAi Impact Factor: 11.922* • Neurophysiology • Epigenetics/chromatin • miRNAs • Neuropharmacology • Noncoding RNAs, miRNAs, siRNAs, RNAi • Genome structure, function, • Noncoding RNAs • Biochemistry • Genomics and evolution • Splicing and genomic diversity • Genetics • Cell proliferation and cell cycle regulation • Whole genome and whole • RNA localization • Cell and molecular biology • DNA replication, recombination/repair exome sequencing • Splicing mechanism • Gene regulation • Human genome variation • RNA decay • Posttranscriptional and • Cancer genomics • Translation and its control posttranslational control • Epigenomics • RNA virology • Developmental biology • Genome medicine • tRNA biology • Signal transduction • Population genomics • Ribosome assembly • Neurobiology • Single-cell genomics • Structural biology • Systems biology • Metagenomics • Structural biology • Genomic disease mechanisms • Bioinformatics • Systems biology *2016 ISI Journal Citation Report • Bacteria and viruses • Genome engineering 2 • Plant biology Review JOURNALS

Cold Spring Harbor Molecular Case Cold Spring Harbor Cold Spring Harbor Studies Perspectives Perspectives www.molecularcasestudies.org in Biology in Medicine • Monthly online publication www.cshperspectives.org www.perspectivesinmedicine.org • Open access journal in the field of precision medicine Impact Factor: 8.769* Impact Factor: 3.968*

• Molecular, cell, and • Translational medicine Now Indexed in PubMed developmental biology • New therapeutic strategies • Genomics • Genetics • Molecular pathology • Proteomics • Evolutionary biology • Cancer therapy • Metabolomics • Neuroscience • Genetics • Pharmacogenomics • Cancer biology • Infectious disease • Biomarker analysis • Immunology • Immunology • Cancer • Molecular and cell biology • Neurological conditions • Monthly online review journals • Unmatched in depth and breadth of coverage • Articles grouped together to form subject collections covering new and fast-moving areas of life science • Each subject collection commissioned by eminent editors in that field and containing 20–25 review articles written by leading researchers of that subject area • Unparalleled subject collections, combined with authoritative analysis, provide your company with the perfect platform 3 Methods & RESOURCES

Cold Spring Harbor Protocols BioSupplyNet www.cshprotocols.org www.biosupplynet.com • Monthly online methods journal • Industry standard in bioscience directories • Fully searchable database • Designed to assist scientists and • 3,000 protocols posted researchers in finding and obtaining the products that they need, quickly and easily • Cutting-edge and classic protocols from laboratories around the world • Hosts more than 6,500 participating companies and more than 20,000 products • Interactive resource presents step- and services by-step instructions for experimental procedures with detailed recipes, • Listing your company provides additional cautions, and troubleshooting tips traffic to your website, qualified sales leads, and increased consumer awareness of your products and brand

• Inserts • Issue and special • Mobile ads Strategic SOLUTIONS • Polybagged supplement • Social media sponsorships Further Enhance Your Visibility outserts • Sponsorship • Posters Build your brand and increase awareness of your products and services • Belly bands or support of • Reprints CSHL meetings in the life science community by adding any of these unique options to • Tip-ons and your print or online ad campaign: tip-ins • Special themed topic collections

4 Online ADVERTISING 12,009,696 TOTAL PAGES ACCESSED in 2017* Monthly Visits* 522,139 • Genes & Development 153,942 With more than 6.3 million visitors, there is no question that the journals of CSHLP • Genome Research 112,187 are well accessed. Incorporating them into your online marketing mix will provide you • RNA 29,911 with superior visibility to our high-quality, focused research communities in industry, • Learning & Memory 20,822 academia, and government. • Cold Spring Harbor Molecular Case Studies 1,806 • Cold Spring Harbor Protocols 121,525 Banner Ads • Cold Spring Harbor Perspectives in Biology 56,236 • Cold Spring Harbor Perspectives in Medicine 24,054 • BioSupplyNet 1,656

Journals leaderboard: 468 × 60 pixels Monthly Page Views* 1,000,808 • Genes & Development 299,894 • Genome Research 230,373 • RNA 64,762 • Learning & Memory 38,474 • Cold Spring Harbor Molecular Case Studies 4,770 Protocols leaderboard: 300 × 60 pixels • Cold Spring Harbor Protocols 205,789 • Cold Spring Harbor Perspectives in Biology 108,166 • Cold Spring Harbor Perspectives in Medicine 43,438 • BioSupplyNet 5,142

Mobile site banner: 288 × 50 pixels Monthly Unique Visitors* 319,699 • Genes & Development 83,984 • Genome Research 63,039 • RNA 16,403 • Learning & Memory 14,278 • Cold Spring Harbor Molecular Case Studies 1,302 • Cold Spring Harbor Protocols 80,329 BioSupplyNet home-page Journals tower: • Cold Spring Harbor Perspectives in Biology 40,370 banner: 130 × 139 pixels 120 × 600 pixels • Cold Spring Harbor Perspectives in Medicine 18,498 • BioSupplyNet 1,496

*Google Analytics 5 E-Mail ALERTS

Deliver your company’s message to your target audience. Available options:

Regular Mails 1× per month when the current issue posts

Special Mails multiple times per month and includes all future, awareness, and publish-ahead-of-print alerts

Two sponsored message slots: • Primary • Secondary

All of our alerts are opt-in and double qualified.

Monthly E-Alerts Requested* 104,347 • Genes & Development 41,523 • Genome Research 31,762 • RNA 12,050 • Learning & Memory 11,995 • Cold Spring Harbor Molecular Case Studies 307 • Cold Spring Harbor Protocols 1,993 • Cold Spring Harbor Perspectives in Biology 3,507 • Cold Spring Harbor Perspectives in Medicine 1,210

*HighWire Data

6 Additional OPPORTUNITIES

PDF Sponsorship Collection Sponsorship TOC Page Sponsorship Your banner will appear on the PDF of specific Cold Spring Harbor Your company banner will remain attached to papers or will sponsor all articles in an issue of Perspectives in Medicine the TOC page of a specific issue for the year. your choice! Cold Spring Harbor Perspectives in Biology Monthly TOC Page Downloads* 18,243

Monthly PDF Downloads* 439,777 Target a specific subject area by sponsoring • Genes & Development 6,607 • Genes & Development 161,267 a specific article or the full collection. • Genome Research 6,689 • Genome Research 129,708 Includes banners, PDF sponsorships, and • RNA 1,243 • RNA 49,682 open-access options. • Learning & Memory 651 • Learning & Memory 14,601 • Cold Spring Harbor Molecular • Cold Spring Harbor Molecular Case Studies 238 Case Studies 1,389 • Cold Spring Harbor Protocols 1,402 • Cold Spring Harbor Protocols 23,234 • Cold Spring Harbor Perspectives • Cold Spring Harbor Perspectives in Biology 835 in Biology 46,145 • Cold Spring Harbor Perspectives • Cold Spring Harbor Perspectives in Medicine 578 in Medicine 13,751

*HighWire Data 7 Print RATES

1 Journals Full Page | 4 Color /2 Page | 4 Color Prime Position | 4 Color Genes & Development $1,650 $1,465 $2,190 Genome Research $4,350 $2,760 $4,950 RNA $1,560 $1,380 $2,000 Frequency Discounts Available: Call for pricing! Employment/Meeting Announcements

1 Full Page | B/W /2 Page | B/W Online Only $800 $650 $200

8 Online RATES

Research Journals Review Journals E-Alerts

Leaderboard Banner Cold Spring Harbor Perspectives Genes & Development Home Page in Biology/Medicine • Primary: $850 net per e-TOC • 1×: $1,000 net per month • Half-year sponsorship: $3,500 net • 12×: $650 net per e-TOC • 6×: $750 net per month • Full-year sponsorship: $6,000 net • 24×: $450 net per e-TOC • 12×: $500 net per month • Secondary: $350 net per e-TOC Run of Site Methods and Resources • Special Alerts: $400 net per month • 1×: $750 net per month Cold Spring Harbor Protocols Genome Research • 6×: $500 net per month • Half-year sponsorship: $3,500 net • Primary: $750 net per month • 12×: $350 net per month • Full-year sponsorship: $6,000 net • 6×: $650 net per month • 12×: $500 net per month Tower Banner BioSupplyNet • Secondary: $300 net per month Home Page • Enhanced listing: $650 net per year • Special Alerts: $400 net per month • 1×: $1,500 net per month • Home-page banners: Call for pricing • 6×: $1,200 net per month • Kit postings: $400 unlimited per month RNA • 12×: $750 net per month • Primary: $600 net per month Run of Site • 6×: $500 net per month • 1×: $1,000 net per month • 12×: $400 net per month • 6×: $750 net per month • Secondary: $200 net per month • 12×: $500 net per month • Special Alerts: $400 net per month Cold Spring Harbor Protocols Additional • $400 net per month Online Opportunities: Cold Spring Harbor Perspectives Call for in Biology/Medicine pricing! • $400 net per month Includes regular and special alerts

9 Preferred PACKAGES

Our cost-effective packages are designed to help you get the most out of your budget!

Mobile Package E-Alert Packages • Go everywhere our readers go! Access our • Own ALL regular alerts (12×): $4,200 per journal readership on our mobile websites! • Own ALL special alerts (12×): $2,400 per journal EXCLUSIVE banner placement: • Own ALL regular and special alerts (24×): $650 for the year per journal $6,000 per journal EXCLUSIVE: Own ALL regular and special alerts, primary, and secondary positions (24×): $10,000 per journal—Save OVER 30%! Journals: Print and Online Packages • Book any 6× print or banner ads at regular price, in any journal, and receive a FREE enhanced listing and featured home-page banner Methods and Resources Packages on BioSupplyNet. • Book any 6× banner ad at regular price in OR Cold Spring Harbor Protocols and receive a FREE enhanced listing on BioSupplyNet. • Book any 12× print or banner ad at regular price, • Book an enhanced listing on BioSupplyNet and in any journal, and receive all of the above PLUS receive one free month unlimited kit postings. one month free kit posting on BioSupplyNet.

OR…Create your own package!

Please note: All packages must be prepaid.

10 Advertising Specifications:PRINT & ONLINE

Display Ad Sizes General Advertising Policies Cancellation Policy • Full page CSHL reserves the right to decline Cancellations must be received any advertisement. CSHL will not by a minimum of four weeks prior • Trim size: 8.5" × 11" be liable for any consequential loss to material deadline date. Any • Bleed size: 8.75" × 11.25" or damage occasioned by failure of order cancelled after the four-week any advertisement to appear from deadline stated in Media Information • Live copy size: 8" × 10.5" any cause whatsoever, nor does it will incur the full insertion cost. No • No bleed: 7.5" × 10" accept liability for any advertisement cancellation, including those sent by • Half page vertical: 3.625" × 10" published. Conditions applying to fax, will be accepted without written an order should be incorporated acknowledgment from CSHL. • Half page horizontal: 7.5" × 4.875" in the order. In the event that copy Please submit your digital advertisement as a high-resolution (press- instructions are not received by the Short Rates and Rebates copy deadline, CSHL reserves the optimized) PDF file. We also accept TIFF and EPS files. Please do not send right to repeat the copy last used. Advertisers will be short-rated if, within ads that are embedded in a text file such as MS Word, Excel, or PowerPoint. Late delivery of material after final the calendar year, they do not advertise copy deadline may incur forfeiture at the frequency on which their billings of space booked at full costs. Copy have been based (will be billed at a Online Ad Sizes matter must conform to CSHL higher rate). Advertisers will be rebated if, within the calendar year, they use • Journals leaderboard banner: 468 × 60 pixels published requirements; a charge will be incurred for any additional work sufficient additional space to warrant a • Journals tower banner: 120 × 600 pixels involved. CSHL will not be responsible lower rate than the rate at which they • Cold Spring Harbor Protocols leaderboard banner: 300 × 60 pixels for the insurance of artwork and other were originally billed. • Cold Spring Harbor Protocols tower banner: 120 × 600 pixels advertisement material delivered by advertiser to CSHL and cannot accept Agency Discount • BioSupplyNet featured product banner: 130 × 139 pixels liability for any loss or damage. Agency commission of 15% to • BioSupplyNet promotional banner: 130 × 180 pixels recognized agencies on space, color, • BiosupplyNet tower banner: 120 × 600 pixels and position, if paid within 30 days. Classified ads are not eligible for • Mobile site banner: 288 × 50 pixels discount. File format: GIF or JPEG. Animated GIFs can loop up to four screens. File size: 40 KB (maximum of 70 KB) Bit depth: 5-bit color maximum

11 Bonus DISTRIBUTION

With a direct connection to the Laboratory, 2018 Meetings Schedule the Press, and its publications, your company can benefit from all that the Laboratory has to Mar Apr May offer. The most distinct and unique advantage is the exclusive bonus distribution that our • Systems Biology: • The PARP Family & • Nuclear Organization titles have at all CSHL meetings and courses. Global Regulation of ADP-Ribosylation & Function Gene Expression • Neuronal Circuits • Biology & Genomics This exclusivity is something that • Protein Homeostasis in of Social Insects NO OTHER publication can offer. Health and Disease • The Biology of Genomes • Gene Expression • Regulatory & & Signaling in the Non-Coding RNAs A well-placed ad can deliver your company Immune System • Retroviruses message directly into the hands of the top • Starr Cancer Consortium • 83rd Symposium: scientists and researchers in their fields from • AACR* Brains & Behavior — around the world! Global marketing does not Order & Disorder in get more direct than that. the Nervous System

Jul Aug Sep

• Glia in Health & Disease • Mechanisms & • Translational Control Models of Cancer • Epigenetics & Chromatin • Genome Engineering: The • Molecular Mechanisms CRISPR/Cas Revolution of Neuronal Connectivity • Single Biomolecules

Oct Nov Dec

• Mechanisms of Aging • Probabilistic Modelling • ASCB* • Germ Cells in Genomics • BioHistory • Biological Data Science

• Nutrient Signaling • Neurodegenerative *Non-CSHL Meeting Diseases: Biology • Transposable Elements & Therapeutics • ASHG* 12 Contact INFORMATION

Marcie Siconolfi Head—Advertising Sales & Sponsorship

516-422-4010 [email protected]

Corrisa Farmer Advertising Account Manager

516-422-4011 [email protected]

Mailing Address

Cold Spring Harbor Laboratory One Bungtown Road Cold Spring Harbor, NY 11724

Cold Spring Harbor Laboratory Press 500 Sunnyside Boulevard Woodbury, NY 11797