Date of Document: September 24, 2021

CURRICULUM VITAE

Musaddiq J. Awan MD

Assistant Professor Department of Radiation Oncology

OFFICE ADDRESS: Froedtert East Clinics 9200 W Wisconsin Ave Milwaukee, WI 53226

EDUCATION: 2004 - 2007 B.S. in Chemistry, Magna cum Laude Honors, University of Maryland, College Park, MD 2004 - 2007 B.S. of Science in Mathematics: Cum Laude Honors,, University of Maryland, College Park, MD 2007 - 2012 M.D., University of Maryland School of Medicine, Baltimore, MD

POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS: 2013 - 2014 Internship, George Washington University Hospital, 900 23rd Street, NW, Washington, D.C., WA 20037 2014 - 2018 Resident, Radiation Oncology, Case Western Reserve University / University Hospitals Case Medical Center, 10900 Euclid Ave, Cleveland, OH 44106 2016 - 2017 Chief Resident, Radiation Oncology, Case Western Reserve/University Hospitals Case Medical Center, 10900 Euclid Ave, Cleveland, OH 44106

FACULTY APPOINTMENTS: 09/01/2018 - Present Instructor, Radiation Oncology, Medical College of Wisconsin, Milwaukee, WI 07/01/2019 - Present Assistant Professor, Radiation Oncology, Medical College of Wisconsin, Milwaukee, WI

EDUCATIONAL ADMINISTRATIVE APPOINTMENTS: 2006 - 2007 Teacher. Taught courses and tutored students for the MCAT, OAT, PCAT and DAT exams., Kaplan Inc., College Park Center

HOSPITAL STAFF PRIVILEGES: 09/01/2018 - Present Assistant Professor, Radiation Oncology, Froedtert West Bend, 3200 Pleasant Valley Road, West Bend, WI 53095 09/01/2018 - Present Assistant Professor, Radiation Oncology, Clement J. Zablocki Veterans Affairs Medical Center, 5000 W. National Avenue, Milwaukee, Milwaukee, WI 53295 09/01/2018 - Present Assistant Professor, Radiation Oncology, Froedtert Memorial Lutheran Hospital,, 9200 W. Wisconsin Avenue, Milwaukee, WI 53226 09/01/2018 - Present Assistant Professor, Radiation Oncology, Children's Hospital of Wisconsin, 9000 W. Wisconsin Avenue, Milwaukee, WI 53226 09/01/2018 - Present Assistant Professor, Radiation Oncology, Froedtert Menomonee Falls Hospital, W180 N8085 Town Hall Road, Menomonee Falls, WI 53051

SPECIALTY BOARDS AND CERTIFICATION:

Board Certified Issue Date Expiration American Board of Radiology 05/16/2019 05/16/2029

1 / 11 Licensure Number Issue Date Expiration Wisconsin State Medical 69742-20 07/24/2018 10/31/2023 License

AWARDS AND HONORS: 2004 Banneker-Key Scholarship Award - merit-based full scholarship for incoming freshman, Banneker-Key 2005 CRC Press Freshman Achievement Award - Awarded to one freshman chemistry major for outstanding achievement 2006 Outstanding Achievement Award - Awarded for outstanding academic achievement in the College of Life Sciences, College of Chemical and Life Sciences 2007 Mathematical and Physical Sciences Dean's Award for Academic Achievement -Awarded for outstanding achievement in the College of Computer, Mathematical and Physical Sciences , College of Computer 2007 University Honors Citation - Awarded for completing the requirements of the University Honors Program, University of Maryland @ College Park 2009 Howard Hughes Medical Institute Research Scholar - One of 42 one-year research positions at the NIH awarded to medical, dental or veterinary students., NIH 2010 Evalee Schwarz Charitable Trust for Education Grant - Merit-based interest-free loan to be used for educational costs 2011 Alpha Omega Alpha - Inducted into the medical school honor society , University of Maryland Chapter 2012 Radiation Oncology Research Scholarship - Awarded for project entitled "Can Breast MRI Accurately Select Patients for Treatment With Pre-Operative APBI?", University of Maryland 2013 Anderson Idol 2013, MD Anderson Cancer Center annual talent show winning act 2017 Abstract-Development of Laryngeal Cancer Nomograms from Pooled Data of Two Trials of Concurrent Chemoradiation: NRG Oncology RTOG 0129 and RTOG 0522 , Best of ASTRO

MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES: 2004 - 2007 Muslim Students Association (Member) 2007 - 2012 American Medical Association (AMA) (Member) 2008 - 2012 Student National Medical Association (Member) 2014 American Board of Radiology (ABR) (Candidate) 2014 American Society of Therapeutic Radiation Oncology (ASTRO) (Member) 2016 Radiologic Society of North America (RSNA) (Member)

EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS: Journal Review 2015 Invited Reviewer, BMC Cancer 2016 - 2017 Invited Reviewer, Oral Oncology 2017 Invited Reviewer, International Journal of Radiation Oncology, Biology and Physics 2018 Invited Reviewer, The British Journal of Radiology 2019 - 2020 Head and Neck 2020 Frontiers Oncology 2021 Journal of Clinical Oncology Clinical Cancer Informatics

LOCAL/REGIONAL APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: 2008 - 2009 Journal Club Member, University of Maryland 2008 Organizer, Community FEST 2008: Giving Baltimore the Tools It Needs to Stay Healthy 2009 Student Member, Pathophysiology and Therapeutics II Course Committee 2009 Forum Attendee, Clinical Investigator Student Training 2010 Attendee, Institute Immunology Science Meeting, Howard Hughes Medical Institute Immunology 2015 - 2018 Committee Member, QA/QI Committee, Dept. of Radiation Oncology, Case Western Reserve University/University Hospitals Case Medical Center. 09/01/2018 Member, Skin Cancer Disease Oriented Team, Medical College of Wisconsin 09/01/2018 - Present Member, Head and Neck Cancer Disease Oriented Team, Medical College of Wisconsin 2020 - Present Member, Faculty Counsel, Medical College of Wisconsin

2 / 11 NATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: 2006 Committee Member, Hospitality Committee, MSA National East Zone Conference 2008 Board of Directors, Logistics, SNMA National Leadership Institute and NMA 2008 - 2009 Community Service Co-Chair, Community Service Committee, Student National Medical Association 2016 Committee Member, Radiation Safety, University Hospitals 2016 - Present Committee Member, Guidelines Sub-Committee, American Society of Radiation Oncology (ASTRO) 2018 - Present Committee Member, Standardizing Normal Tissue Contouring for Radiation Therapy Treatment Planning, American Society of Therapeutic Radiation Oncology (ASTRO) 2018 - 2019 Committee Member, Skin Guidelines Committee, American Society of Therapeutic Radiation Oncology (ASTRO) 06/24/2021 Ad Hoc Reviewer, Grant Applications for two Omnibus Funding Opportunity Announcements (FOA) PAR-20-292 (R21) and PAR-20-052 (R03), NCI

RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS:

Active Peer Review Title: DEHART: Dose-Escalated Hypofractionated Adaptive Radiation Therapy for Head and Neck Cancers Source: NCI Role: PI PI: AWAN, M Dates: 01/01/2021 - Present Direct Funds: $275,000

Title: A Phase I Trial of MR-Guided Dose- Escalated Hypofractionated Adaptive Radiation Therapy and Immunotherapy in Primary Metastatic or Very Locally Advanced Patients With Head and Neck Cancer Source: NIH R21 Award Role: PI Dates: 01/26/2021 - 12/01/2022

Title: Investigation of the impact of social isolation stress on oral cancer pathobiology through use of a humanized patient-derived xenograft mouse model Source: ENT Otoclinomoics Role: Co-PI PI: Joseph Zenga Dates: 05/15/2021 - Present Direct Funds: $30,000

INVITED LECTURES/WORKSHOPS/PRESENTATIONS: Local AWAN, MJ., Eliminating Health Disparities Through Empowerment and Education., Logistics, SNMA Region VI Conference, 2008 AWAN M., Don't Deescalate: Lessons from Two Trial of HPV + Head and Neck Cancer, Radiation Oncology Grand Rounds, Medical College of Wisconsin, 01/09/2019 AWAN, M, “120 Gy, Man? This is Crazy! How to Look at the Data, Ignore the Numbers, Close Your Eyes,

3 / 11 and Re-Irradiate Head and Neck Cancers”, Radiation Oncology Grand Rounds, Medical College of Wisconsin, 05/19/2020 AWAN, M, Radiation Emergencies, Radiation Oncology Resident Conference, Medical College of Wisconsin, 07/27/2020 - 07/28/2020 AWAN, M, Clinical Treatment Setup Practicum for Residents, Medical College of Wisconsin, 08/12/2020 AWAN, M, Think like a surgeon: Contouring and treatment planning considerations in head and neck cancer, Radiation Oncology Grand Rounds, Medical College of Wisconsin, 04/28/2021

National Clinical Trials Methodology Workshop, 2018 AWAN, M, A Nomogram for Outcomes after Chemoradiation for Non-HPV-Related Squamous Cell Carcinomas of the Head and Neck – A Pooled Analysis of NRG Oncology RTOG 0129 & 0522, ASTRO Annual Meeting 2019, Chicago, IL, 09/16/2019

International AWAN, M., Clinical Experience on the ELEKTA MR Unit, Elekta Meeting, Tokyo, Japan, 07/26/2019

COMMITTEE SERVICE: Medical College of Wisconsin 12/12/2018 - Present Committee Member, STIRC Subcommittee On Nomenclature Standardization, Radiation Oncology, Medical College of Wisconsin 01/29/2020 - Present Committee Member, STIRC 3D Printing in Radiation Oncology, Radiation Oncology, Medical College of Wisconsin 04/2021 - Present Member, Head and Neck Planning Standardization Planning Committee, Radiation Oncology, Medical College of Wisconsin Committee Member, ROCKET, Radiation Oncology, Medical College of Wisconsin

Hospital 10/16/2019 - Present Committee Member, Dental Care for Froedtert Head and Neck Cancer patients Task Force, Head & Neck, Skin, and Orbital Cancer Programs, Froedtert and the Medical College of Wisconsin 02/2021 - Present AU Brachytherapy/Rad Onc Representative, Chairperson, Radiation Safety Committee, Community Hospital Division, Radiation Oncology, Froedtert and the Medical College of Wisconsin

MEDICAL COLLEGE TEACHING ACTIVITIES: Medical Student Education 09/01/2018 - Present Community Oncology Elective Rotation 01/01/2019 - 12/31/2019 Clinical Apprenticeship Course for M1/M2

Resident and Fellow Education 11/07/2018 Orapharynx, Radiation Oncology Resident Conference 11/21/2018 Early Larynx Cancer - Radiation Oncology Resident Conference 12/19/2018 CNS Physiology, Radiation Oncology Physics Resident Conference 05/05/2019 Hyperthermia, Radiobiology Resident Conference 06/17/2019 Treatment Planning in Head and Neck, Radiation Oncology Resident Conference 08/19/2019 Sino-Nasal H&N, Radiation Oncology Resident Conference 10/16/2019 CNS Physiology, Radiation Oncology Physics Resident Lecture 11/25/2019 H&N Advanced larynx/hypopharynx, Radiation Oncology Resident Conference 12/02/2019 H&N Oral Cavity/Unknown Primary, Radiation Oncology Resident Conference 12/03/2019 Skull Base Lecture, Radiation Oncology Resident Conference 12/04/2019 Nasopharynx Lecture, Radiation Oncology Resident Conference 12/10/2019 Oxygen Effect and Re-Oxygenation, Radiation Oncology Physics Residents Conference 12/16/2019 Thyroid Lecture, Radiation Oncology Resident Conference 12/17/2019 Staff, Radiation Oncology Resident Conference 2019 - Present Head and Neck Cancer Curriculum for Senior Radiation Oncology Residents

4 / 11 2019 - Present Head and Neck Cancer Curriculum for Junior Radiation Oncology Residents 10/20/2020 ENT Resident Lecture: Intro to Head and Neck Radiation 11/18/2020 CNS Physiology, Radiation Oncology Physics Resident Conference 12/28/2020 - 12/29/2020 Resident Conference, Melanoma and Merkel Cell 02/22/2021 - 02/23/2021 Resident Conference, Diffuse Large B Cell Lymphoma 02/23/2021 Hyperthermia, Radiobiology Resident Conference

EXTRAMURAL TEACHING: Resident and Fellow Education 05/01/2021 - 05/02/2021 Osler Institute, Mock Radiation Oncology Oral Examination for Head and Neck/Skin Cancers

PROGRAMMATIC DEVELOPMENTS:

Clinical Programs 10/16/2019 - Present Head and Neck Cancer Dental Quality Initiative

COMMUNITY SERVICE ACTIVITIES: 2005 PSA Earthquake Relief Fundraiser, Organizer and Speaker 2006 Eyes Wide Open, Volunteer.

ORAL PRESENTATIONS: 09/2017 Development efLaryngeal Cancer Nomogramsfrom Pooled Data if Two Trials ef Concurrent Chemoradiation: NRG Oncology RTOG 0129 and RTOG 0522. American Society of Radiation Oncology National Meeting (ASTRO), San Diego, CA.

POSTER PRESENTATIONS: 05/2005 Rollinson Fellowship Presentation, University of Maryland at College Park. Presented work on synthesis of selectively methylated 1,5-diaminonaphthalenes. 05/2010 Howard Hughes Medical Institute Meeting of Medical Fellows, Research Scholars and Early Career Awardees, Howard Hughes Medical Institute, Chevy Chase, MD. Presented poster titled Inducing Metastasis in a PIEN-1-,p5;-I- Mouse M odel if Prostate Cancer. 04/2011 National Student Research Forum, University of Texas Medical Branch, Galveston, TX. Presented poster titled Inducing Metastasis in a PTEN- 1-p, 5;-I- Mouse M odel if Prostate Cancer. 10/2012 American Society of Radiation Oncology National Meeting, Boston, MA. Presented poster titled Can Breast MRI Select Patients For Treatment With Pre-operative APB!? 09/2016 American Society of Radiation Oncology National Meeting, Boston, MA. Presented poster titled Post-treatment PET/ CT andp 16 statusfar Neck Management in Local!J Advanced Head and Neck Cancer cifter Definitive Chemoradiation. 09/2016 American Society of Radiation Oncology National Meeting, Boston, MA. Presented poster titled Re- irradiation Outcomes After Upfront Larynx Preseroation or Total Laryngectomy: A Multi institutional Ana!J sis.

RESEARCH POSITIONS: 2005 - 2006 Undergraduate Researcher and Rollinson FEllow, Dept. of Chemistry and Biochemistry: University of Maryland at College Park, Mentor: Seven Rokits, PHD. Synthesis UV-V Spectroscopy and Flourescence Spectroscopy of Polycyclic Aromatic Amines for Photochemical Studies of Excess Electron transfer through DNA. 2008 - 2012 Student Researcher, The Breast Center: University of Maryland Baltimore, Mentor: Steven Feigenberg, M.D. Radiologic Imaging as a Predictive Tool of Metastatic Lymph Node Status in Newly Diagnosed Breast Cancer Patients. The Role of MRI in Patients Who are Candidates for Accelerated

5 / 11 Partial Breast Irradiation (APBI) 2009 - 2010 Guest Researcher, National Cancer Institute: National Institutes of Health at Bethesda. Mentor: Kathleen Kelly, PhD. Mechanisms of Prostate Cancer Metastasis in PTEN(-/-), P53(-/-) Mouse Cell Lines. 2012 - 2013 Postdoctoral Fellow, Department of Radiation Oncology: The University of Texas MD Anderson Cancer Center, Mentor: Clifton Fuller, M.D. PhD. Developing a training program for contouring organs-at-risk in the head and neck. Auto-segmentation of Head and Neck Organs-at risk. Quality Assurance and Implementation of Deformable Image Registration Algorithms in the Head and Neck. Monitoring long-term Treatment Outcomes in Patients who Received Radiation Treatment for Head and Neck Cancer. Dosimetric Study of Head and Neck Cancer Patients with Late-onset Dysphagia. Studying the Role of MR Sequences in Monitoring Radiation Treatment in the Extra-cranial Head and Neck.

SPECIAL SKILLS: Stereotactic Body Radiotherapy, Prostate Seed Implantation, Tandem and Split Ring Implants, Syed Implants, High-dose Rate Brachytherapy, Proton Treatment Planning, Total Body Irradiation, Gamma Knife Radiosurgery, Nomogram Development, Deformable Image Registration, Pinnacle Treatment Planning System, MIM, DICOM File Structure, Matlab, C++, Ruby on Rails, R, JMP, Javascript, Linux, Mice Handling, Bioluminescent Imaging, Western Blotting, Immunohistochemistry, qRT-PCR, Tumorigenic Cell Assays, Tissue Culture, Microsoft Excel, Microsoft Powerpoint, Microsoft Access, FileMaker Pro.

BIBLIOGRAPHY Refereed Journal Publications/Original Papers 1. AWAN M, Cohen R, Campassi C, Kesmodel S, Bellavance E, Tkaczuk K, Feigenberg, S. Breast MRI and Its Impact on Partial Breast Irradiation. Applied Radiation Oncology, October, 2012. 2. AWAN, M, Kalpathy-Cramer, J, Gunn GB, Beadle BM, Garden AS, Phan ], Holliday E, Jones WE, III, Patel A, Choi ], Clyburn V, Tantiwongkosi B, Rosenthal DI, Fuller, CD. Prospective Assessment of an Atlas- Based Intervention Combined With Real-Time Software Feedback in Contouring Organs-at-Risk in the Head and Neck: Quantitative assessment of conformance to expert delineation. Practical Radiation Oncology, July, 2013. PMID:24674363 3. Kalpathy-Cramer J, AWAN M, Bedrick S, Rasch C, Rosenthal DI, Fuller CD. Development of a Software for Quantitative Evaluation Radiotherapy Target and Organ-at-Risk Segmentation Comparison. Journal of Digital Imaging, February, 2014. PMID: 24043593 4. AWAN MJ, Mohamed AS, Lewin JS, Baron CA, Gunn GB, Rosenthal DI, Holsinger FC, Schwartz DL, Fuller CD, Hutcheson KA. Late Radiation-Associated Dysphagia (late-RAD) With Lower Cranial Neuropathy After Oropharyngeal Radiotherapy: A Preliminary Dosimetric Comparison. Oral Oncology, August, 2014. PMID: 24906528 5. Mavroidis P, Giantsoudis D, AWAN MJ, Nijkamp J, Rasch CR, Duppen JC, Thomas CR Jr, Okunieff P, Jones WE 3'd, Kachnic LA, Papanikolaou N, Fuller CD; Southwest Oncology Group Radiation Oncology Committee. Consequence of Anorectal Cancer Atlas Implementation in the Cooperative Group Setting: Radiobiologic Analysis of a Prospective Randomized in silico Target Delineation Study. Fuidiotherapy & Oncology, July, 2014. PMID: 24996454 6. Walker, GV, AWAN M, Tao R, Koay EJ, Boehling NS, Grant JD, Sittig DF, Gunn GB, Garden AS, Phan, Morrison WH, Rosenthal DI, Mohamed AS, Fuller CD. Prospective Randomized Double-blind Study of Atlas-Based Organ-at-Risk Autosegmentation-Assisted Radiation Planning in Head and Neck Cancer. Fuidiotherapy & Oncology, September 2014. PMID: 25216572 7. Mohamed AS, Ruangskul MN, AWAN MJ, Baron CA, Kalpathy-Cramer J, Castillo R, Castillo E, Guerrero T, Kocak-Uzel E, Yang], Court L, Kantor M, Gunn GB, Colen R, Frank SJ, Garden AS, Rosenthal DI, Fuller CD. Quality Assurance Assessment of Diagnostic and Therapy-Simulation Computed Tomography Image Registration for Head and Neck Radiotherapy: Anatomic Region-of-Interest- Based Comparison of Rigid and Deformable Algorithms. Fuidiology, November, 2014. PMID: 25380454 8. Sturgeon JD, Cox JA, Mayo LL, Gunn GB, Zhang L, Balter PA, Dong L, AWAN M, Kocak-Uzel E, Mohamed AS, Rosenthal DI, Fuller CD. Improved human observer performance in digital reconstructed radiograph verification in head and neck cancer radiotherapy. Int J Comput Assi St

6 / 11 Fuidiol Surg., December, 2014. PMID: 25477277 9. Baron CA, AWAN MJ, Mohamed AS, Akel I, Rosenthal DI, Gunn GB, Garden AS, Dyer BA, Court L,Sevak PR, Kocak-Uzel E, Fuller CD. Estimation of Daily Interfractional Larynx Residual Setup Error after Osocentric Alignment for Head and Neck Radiotherapy: Quality Assurance Implications for Target Volume and Organs-at-risk Margination using Daily CT On-rails Imaging. J Appl Clin Med. Plys., January, 2015. PMID: 25679151 10. Tang C, Fuller CD, Garden AS, AWAN MJ, Colen RR, Morrison WH, Frank SJ, Beadle BM, Phan ],Sturgis EM, Zafereo ME, Weber RS, Rosenthal DI, Gunn GB. Characteristics and Kinetics of Clymph Nregression after Radiation Therapy for Human Papillomavirus-associated Oropharyngeal Carcinoma: Quantitative Image Analysis of Post-radiotherapy Response. Oral Oncology, February, 2015. PMID: 25444304 11. AWAN M, Dyer B, Kalpathy-Cramer, Bongers E, Dahele M, Yang J, Walker GV, Thaker N, Holliday E, Bishop, Thomas CR, Rosenthal DI, Fuller CD. Auto-segmentation of the Brachial Plexus Assessed With TaCTICS. Acta Oncologica, April 2015. PMID: 25279958 12. AWAN M, Liu S, Sahgal A, Das S, Chao ST, Chang EL, Knisely JPS, Redmond K, Sohn JW, Machtay M, Sloan AE, Mansur DB, Rogers LR, Lo SS. Extra-CNS Metastasis from Glioblastoma (ECM-GBM): A Rare Clinical Entity. Expert Review of Anticancer Therapy. May 2015. PMID: 25907706 13. AWAN MJ, Siddiqui F, Schwartz D, Yuan ], Machtay M, Yao M. Application of Positron Emission Tomography/Computed Tomography in Radiation Treatment Planning for Head and Neck Cancers. World Journal of Fuidiology. November 2015. PMID: 26644824 14. AWAN MJ, Dorth J, Mani A, Kim H, Zheng Y, Mislmani M, Welford S, Yuan ], Wessels BW, Lo SS, Letterio J, Machtay M, Sloan A, Sohn JW. Development and Validation of a Small Animal Immobilizer and Positioning System for the Study of Delivery of lntracranial and Extracranial Radiotherapy Using the GammaKnife System. Technology in Cancer Research and Treatment. July 2016. PMID: 27444980 15. Mohamed ASR, Rosenthal DI, AWAN MJ, Garden AS, Kocak-Uzel E, Belal, AM, El-Gowily AG, Phan Beadle BM, Gunn GB, Fuller CD. Methodology for Analysis and Reporting Patterns of Failure in the Era of IMRT: Head and Neck Cancer Applications. Radiat Oncol. July, 2016. PMID: 27460585 16. Sandulache VC, Hobbs BP, Mohamed ASR, Frank SJ, Song], Ding Y, Kalpathy-Cramer J, Hazle JD, Wang], AWAN MJ, Rosenthal DI, Garden AS, Gunn GB, Colen RR, El-shafeey N, El-banan M, Hutcheson KA, Lewin, Chambers MS, Hofstede TM, Weber RS, Lai SY, Fuller CD. Dynamic contrast enhanced MRI detects acute radiotherapy-induced alterations in mandibular microvasculature: prospective assessment of imaging biomarkers of normal tissue injury. Scientific Reports. August, 2016. PMID: 27499209 17. AWAN M, Sharma N, Towe CW, Efird JT, Machtay M, Biswas T. Optimum treatment for mediastinal lymph node positive (N2) resectable non-small cell lung cancer: What is the role for surgery? Expert Reviews of Anticancer Therapy. October, 2016. PMID: 27654059 18. Cardenas CE, Tao R, Wong AJ, AWAN MJ, Kuruvila S, Aristophanous M, Gunn GB, Phan ], Beadle BM,Frank SJ, Garden AS, Morrison WH, Fuller CD, Rosenthal DI. Prospective Qualitative and Quantitative Analysis of Real-time Peer Review Quality Assurance Rounds Incorporating Direct Physical Examination for Head and Neck Cancer Radiation Therapy. International Journal of Radiation Oncology, Biology and Pl Jsics. July 2017. PMID: 28258898 19. Clancy K, Melki S, AWAN M, Li S, Lavertu P, Fowler N, Yao M, Rezaee R, Zender C. Outcomes of Microvascular Free Tissue Transfer in Twice-Irradiated Patients. Microsurgery. September 2017. PMID: 28066911 20. Clancy K, Melki S, AWAN M, Li S, Lavertu P, Fowler N, Yao M, Rezaee R, Zender C. Outcomes of Microvascular Free Tissue Transfer in Twice-Irradiated Patients. Microsurgery. September, 2017. PMID: 28066911 21. Vargo JA, Ward MC, Caudell ]], Riaz N, Dunlap NE, Isrow D, Zakem SJ, Dault J, AWAN MJ, Higgins KA, Hassanadeh C, Beitler ]], Reddy CA, Marcrom S, Boggs DH, Bonner JA, Yao M, Siddiqui F, Trotti AM, Lee NY, Koyfman SA, Ferris RL, Heron DE. A Multi-institution Comparison of SBRT and IMRT for Definitive Re-Irradiation of Recurrent or Second Primary Head and Neck Cancer. International Journal of Radiation Oncology, Biology and Pl?Jsics. April 2017. PMID: 28899556 22. Ward MC, Riaz N, Caudell, Dunlap NE, Isrow D, Zakem SJ, Dault J, AWAN MJ, Vargo JA, Heron DE, I

7 / 11 by the MIRI Collaborative. International Journal of Radiation Oncology, Biology and Pi?J sics. June 2017. PMID: 28865925 23. AWAN MJ, Lavertu P, Zender C, Rezaee R, Fowler N, Karapetyan L, Gibson M, Wasman J, Faulhaber P, Machtay M, Yao M. Post-treatment PET/CT and p16 Status in Predicting Treatment Outcomes of Locally Advanced Head and Neck Cancer after Definitive Radiation. European Journal of Nuclear Medicine and Molecular Imaging. June 2017. PMID: 28091733 24. Mohamed ASR, Cardenas CE, Garden AS, AWAN MJ, Rock C, Westergaard E, Gunn GB, Belal AM, El Gowily AG, Lai SY, Rosenthal DI, Fuller CD, Aristophanous M. Patterns-of-Failure Guided Biological Target Volume Definition for Head and Neck Cancer Patients: FDG-PET and Dosimetric Analysis of Dose Escalation Candidate Subregions. Radiotherapy and Oncology. July 2017. PMID: 28774596 25. Ger RB, Mohamed ASR, AWAN MJ, Ding Y, Li K, Pave XJ, Beers AL, Driscoll B, ElhalAWANi H, Hormuth II DA, van Houdt PJ, He R, Zhou S, Mathieu KB, Li H, Coolens C, Chung C, Bankson JA, Huang W, Wang ], Sandulache VC, Lai SY, Howell RM, Stafford RJ, Yankeelov TE, van der Heide UA, Frank SJ, Barboriak DP, Hazle JD, Court LE, Kalpathy-Cramer J, Fuller CD. A Multi- Institutional Comparison of Dynamic Contrast-Enhanced Magnetic Resonance Imaging Parameter Calculations. Scientific Reports. September 2017. PMID: 28894197 26. AWAN MJ, Nedzi L, Wang D, Tumati V, Sumer B, Xie XJ, Smith I, Truelson J, Hughes R, Myers LL, Lavertu P, Wong S, Yao M. Final Results of a Multi-institutional Phase II Trial of Re-Irradiation with Concurrent Weekly Cisplatin and Cetuximab for Recurrent or Second Primary Squamous Cell Carcinoma of the Head and Neck. Annals of Oncology. January 2018. PMID: 29346519 27. Caudell, Ward MC, Riaz N, Zakem SJ, AWAN MJ, Dunlap NE, Isrow D, Hassanzadeh C, Vargo JA, Heron DE, Marcrom S, Boggs DH, Reddy CA, Dault J, Bonner JA, Higgins KA, Beitler JJ, Koyfman SA, Machtay M, Yao M, Trotti AM, Siddiqui F, Lee NY; Multi-Institution Reirradiation (MIRI) Collaborative. Volume, Dose, and Fractionation Considerations for IMRT-based Reirradiation in Head and Neck Cancer: A Multi-institution Analysis. International Journal of Radiation Oncology, Biology and Pi?Jsics. March 2018. PMID: 29413274 28. Elhal Awani H, Ger RB, Mohamed ASR, AWAN MJ, Ding Y, Li K, Pave XJ, Beers AL, Driscoll B, Hormuth IiDA, van Houdt PJ, He R, Zhou S, Mathieu KB, Li H, Coolens C, Chung C, Bankson JA, Huang W, Wang], Sandulache VC, Lai SY, Howell RM, Stafford RJ, Yankeelov TE, van der Heide UA, Frank SJ, Barboriak DP, Hazle JD, Court LE, Kalpathy-Cramer J, Fuller CD; Joint Head and Neck Radiotherapy-MRI Development Cooperative. Dynamic contrast-enhanced magnetic resonance imaging for head and neck cancers. Scientific Data. February 2018. PMID: 29557974 29. Baydoun A, Vapiwal N, Ponsky LE, AWAN M, Kassaee A, Sutton D, Podder TK, Zhang Y, Dobbins D, Muzic RF, Traughber B, Machtay M, Ellis R. Comparative Analysis for Renal Stereotactic Body Radiotherapy Using Cyberknife, VMAT and Proton Therapy Based Treatment Planning. J Appl Clin Med Phys. In Press March 2018. PMID: 29542260 30. Bahig H, Yuan Y, Mohamed ASR, Brock KK, Ng SP, Wang J, Ding Y, Hutcheson K, McCulloch M, Baler PA, Lai SY, Al-Mamgani A, Sonke JJ, van der Heide UA, Nutting C, Li XA, Robbins J, AWAN M, Karam I, Newbold K, Harington K, Oelfke U, Bhide S, Philippens MEP, erhaard CHJ, McPartlin AJ, Blanchard P, Garden AS, Roesnthal DI, Gunn GB, Phan J, Cazoulat G, Aristophanous M, McZSpadden kk, Garcia JA, van den Berg CAT, Raaijmakers CPJ, Kerkmeijer L, Doornaert P, Blinde S. Frank SJ, Fuller CD: Magnetic Resonance-based Response Assessment and Dose Adaptation in Human Papillloma Virus Positive Tumors of the Oropharynx treated with Radiotherapy (MR- ADAPTOR): An R-IDEAL stage 2a-2b/Bayesian phase II trial. Clin Transl Radiat Oncol. 2018 24:13:19-23. PMID:30386824 31. Zenga J, Graboyes E, Janz T, Drake V, Rettig E, Desai S, Nickel C, Shabani S, Padhya T, Scarpinato M, Stakler M, Massey B, Campbell B, Shukla M, AWAN M: Salvage of Recurrence after Surgery and Adjuvant Therapy: A multi-insittional Study. Otolaryngol head Neck Surg. 2019, Feb. 12. PMID: 30753110 32. Ward MC, Lee NY, Caudell JJ, Zajichek A, AWAN MJ, Koyfman SA, Dunlpa NE, Zakem SJ, Hassanzadeh C, Marcrom S, Boggs DH, Isrow D, Vargo JA, Heron DE, Siddiqui F, Bonner JA, Beitler JJ, Yao M. A competing risk nomogram to predict severe late toxicity after modern reirradiation for squamous carcinoma of eh head and neck. J. Oral Oncology;90(2019)80-86. PMID: 30846182 33. Yan L, AWAN MJ, Chang T,Lavertu p,Zender c, Rezaee R,Fowler N, Wasman J, Avril NE, Nianyong C, Machtay M,Yao M. Post-radiotherapy PET/CT for predicting treatment outcomes in head and neck cancer after postoperative radiotherapy. European Journal of Nuclear Medicine and Molecular Imaging

8 / 11 (2019) 46:794–800 34. Wright J, Yom S, AWAN M, Dawes S, Fischer-Valuck B, Kudner R, Mailhot- Vega, Rodrigues G. Standardizing Normal Tissue Contouring for Radiation Therapy Treatment Planning: An ASTRO Consensus Paper. Practical Radiation Oncology (2019)9,65-72. 35. Zenga J, Stadler M, Massey B, Campbell B, Shukla MD AWAN M, Schultz C, Wongs, Jackson R, Pipkorn P.Lymph Node Yield From Neck Dissection in HPV-Associated Oropharyngeal Cancer. The Laryngoscope 00:2019 36. Zenga J, Divi V, Stakler M, Massey B, Campbell B, Shukla M, AWAN M, Schultz C, Shreenivas A, Wong S, Jackson R, Pipkorn P. Lymph node yield, depth of invasion, and survival in node-negative oral cavity cancer. Oral Oncology,98(2019)125-131. 37. Likhacheva A,AWAN, M, Barker C, Bhatnagar A, Bradfield L, Brady M, Buzurovic I,Geiger J, Parvathaneni U, Zaky S, Devlin P, Definitive and Postoperative Radiation Therapy for Basal and Squamous Cell Cancers of the Skin: Executive Summary of an American Society for Radiation Oncology Clinical Practice Guideline. Practical Radiation Oncology (2020) 10, 8-20 38. Hall WA, Straza MW, Chen X, Mickevicius N, Erickson B, Schultz C, AWAN M, Ahunbay E, Li XA, Paulson ES. Initial clinical experience of Stereotactic Body Radiation Therapy (SBRT) for liver metastases, primary liver malignancy, and pancreatic cancer with 4D-MRI based online adaptation and real-time MRI monitoring using a 1.5 Tesla MR-Linac. PLoS One. August 2020. PMID: 32764748 39. McDonald BA, Vedam S, Yang J, Wang J, Castillo P, Lee B, Sobremonte A, Ahmed S, Ding Y, Mohamed ASR, Balter P, Hughes N, Thorwarth D, Nachbar M, Philippens MEP, Terhaard CHJ, Zips D, Boke S, Awan MJ, Christodouleas J, Fuller CD, MR-Linac Consortium Head and Neck Tumor Site Group. Initial Feasibility and Clinical Implementation of Daily MR-Guided Adaptive Head and Neck Cancer Radiation Therapy on a 1.5T MR-Linac System: Prospective R-IDEAL 2a/2b Systemic Clinical Evaluation of Technical Innovation. Int J Radiat Oncol Biol Phys. April 2021. PMID: 33340604 40. Awan MJ, Gittleman H, Barnholtz-Sloan J, Machtay M, Nguyen-Tan PF, Rosenthal DI, Schultz C, Huth BJ, Thorstad WL, Frank SJ, Kim H, Foote RL, Lango MN, Shenouda G, Suntharalingam M, Harris J, Zhang Q, Le QT, Yao M, NRG Oncology Group. Risk groups of laryngeal cancer treated with chemoradiation according to nomogram scores - A pooled analysis of RTOG 0129 and 0522. Oral Oncol. February 2021. PMID: 33640577 41. North LM, Harvey E, Vanle B, Shreenivas A, Shukla M, Wong S, Awan M, Zenga J. Frequent omission of radiation after flap reconstruction of head and neck cancer: Are we dooming patients to failure? Oral Oncol. February 2021. PMID: 33612388 42. Elhalawani H, Awan MJ, Ding Y, Mohamed ASR, Elsayes AK, Abu-Gheida I, Wang J, Hazle J, Gunn GB, Lai SY, Frank SJ, Ginsberg LE, Rosenthal DI, Fuller CD. Data from a terminated study on iron oxide nanoparticle magnetic resonance imaging for head and neck tumors. Sci Data. February 2021. PMID: 32081849 43. Elhalawani H, Elgohari B, Lin TA, Mohamed ASR, Fitzgerald TJ, Laurie F, Ulin K, Kalpathy-Cramer J, Guerrero T, Holliday EV, Russo G, Patel A, Jones W, Walker GV, Awan M, Choi M, Dagan R, Mahmoud O, Shapiro A, Kong FS, Gomez D, Zeng J, Decker R, Spoelstra FOB, Gaspar LE, Kachnic LA, Thomas CR Jr, Okunieff P, Fuller CD. An in-silico quality assurance study of contouring target volumes in thoracic tumors within a cooperative group setting. Clin Transl Radiat Oncol. January 2019. PMID: 30775563

Abstracts 1. AWAN M, Bellavance E, Kesmodel S, Ioffe 0, Campassi C, Tkaczuk K, Chumsari S, Bao T, Feigenberg S. Can Breast MRI Select Patients For Treatment With Pre-operative APBI? International Journal of Radiation Oncology, Biology and Physics. October, 2012 2. Tillman HS, Yin JJ, Liu YN, AWAN M, Martin P, Kelly K. Investigation of the Signaling Factors iIvolved in Ras/MAPK-promoted Metastasis in the PTENITP53 Mouse Model. American Association for Cancer Research 104 Annual Meeting. April, 2013 3. AWAN M, Rosenthal DI, Baron CA, Nuanjing C, Holmes MK, Fuller CD. A Dosimetric Comparison of Pharyngeal Constrictor Segmentation Methods during Radiation Treatment for Head-and-Neck Cancer. International Journal of Radiation Oncology, Biology and Physics (October 2013). 4. Sevak PR, AWAN MJ, Gunn GB, Rosenthal DI, Fuller CD. Intensity Modulated Radiation Therapy for T1 Glottic Cancer: Initial Clinical Outcomes. International Journal of Radiation Oncology, Biology and Physics. October, 2013 5. Meshkov D, Guerrero T, Ting X, Pham N, Li M, AWAN M, Castillo S, Castillo R, Tucker S, Liao Z. ATM

9 / 11 Gene Variations Predict Differences in Pretreatment Lung Inflammation in Non-Small Cell Lung Cancer(NSCLC) Patients. International Journal of Radiation Oncology, Biology and Physics. October, 2013 6. Hutcheson KA, AWAN MJ, Mohammed ASR, Baron CA, Gunn GB, Rosenthal DI, Holsinger C, Schwartz DL, Lewin JS, Fuller CD. Late Radiation-Associated Dysphagia (RAD) and Lower Cranial Neuropathy After Oropharyngeal Radiation Therapy: A Case-Control Dosimetric Comparison. American Society of Radiation Oncology. October, 2013 7. Baron C, AWAN MJ, Gunn GB, Rosenthal DI, Fuller CD. The Effect of Larynx Motion on Setup/Delivery Error During Radiation Treatment for Head-and-Neck Cancer. International Journal of Radiation Oncology, Biology and Physics. October, 2013 8. AWAN M, Zafereo M, Lewis CM, Guha-Thakurta N, Debnam ], Gunn G, Phan ], Rosenthal DI, Fuller CD. Interdisciplinary Variation in Segmentation of High-Risk Postoperative Tumor Volumes in the Head and Neck. International Journal of Radiation Oncology, Biology and Physics. October, 2013 9. Walker GV, AWAN M, Tao R, Koay EJ, Garden AS, Gunn GB, Garden AS, Phan L, Morrison WH, Rosenthal DI, Fuller CD. Prospective Randomized Double-Blind Study of Atlas-Based Autosegmentation Assisted Radiation Treatment Planning in Head-and-Neck Cancer. International Journal of Radiation Oncology, Biology and Physics. October, 2013 10. Mohamed AS, Ruangskull M, AWAN MJ, Baron CA, Castillo R, Castillo E, Guerrero TM, Kocak E, Yang, Court L, Gunn GB, Garden AS, Rosenthal DI, Fuller CD. Quality Assurance Assessment of Diagnostic and Therapy-Simulation Computed Tomography Image Registration for Head and Neck Radiotherapy: Anatomic Region-of-Interest-Based Comparison of Rigid and Deformable Algorithms. American Radium Society. April, 2014 11. AWAN M, Kalpathy-Cramer J, Bongers E, Dahele M, Yang], Walker GV, Thaker NG, Holliday E, Bishop A, Thomas CR, Rosenthal DI, Fuller CD. Benchmarking for Organ-at-Risk Auto-segmentation Quality Assurance Using a Multi-Metric Software Assessment. ACR Annual Conference on Quality and Safety. February, 2013 12. Mohamed AS, AWAN M, Kocak E, Beadle BM, Kantor ME, Gunn GB, Garden AS, Rosenthal DI, Fuller CD. Methods for Analysis and Reporting the Patterns of Locoregional Failure In the era of IMRT for Head and Neck Cancer: Deformable Image- Registration-Based Quality Assurance Workflow. International Journal of Radiation Oncology, Biology and Physics, September, 2014 13. Mohamed AS, Aristopahnous M, AWAN MJ, Garden AS, Rosenthal DI, Fuller CD. Biological and Dosimetric Analysis of Locoregional Failure After IMRT for Head and Neck Cancer. International Journal of Radiation Oncology, Biology and Physics, September, 2014. 14. Kim H, AWAN M, Monroe J, Yao M, Machtay M, Shenk R, Sohn J. A Biometric Automated Patient Identification System (BAPIS) for High-throughput Accurate Patient Identification Prior to Radiotherapy and Surgery. International Conference on the Use of Computers in Radiation Therapy Gune (2016) 15. Kim S, Kim H, Lee S, AWAN M, Rangaraj D, Zheng Y, Monroe J, Partel R, Lo S, Machtay M, Sloan A, Sohn J. Volume-Independent Conformity Index for Stereotactic Brain Tumors. American Association of Phycists in Medicine. (August 2016) 16. Ger R, AWAN M, Mohammed AS, Ding Y, Frank S, Howell R, Li Heng, Mohan R, Schellingerhout D, Stafford RJ, Wang J, Fuller CD, Court L. Evaluating DCE-MRI Changes in Salivary Glands of Head and Neck Patients. American Association of Phycists in Medicine. (August 2016) 17. Sandulache VC, Hobbs B, Mohamed ASR, Frank SJ, Hazel ], AWAN MJ, Rosenthal DI, Garden AS, Gunn GB, Ding Y, Wang], Colen R, Hutcheson KA, Lewin JS, Chambers MS, Hofstede TM, Weber RS, Lai S, Fuller CD. Dynamic Contrast-Enhanced MRI Detects Acute Radiation Therapy-Induced Alterations in Mandibular Microvasculature: Prospective Assessment oflmaging Biomarkers of Normal Tissue Injury. American Society of Radiation Oncology.September 2016 18. Campbell SR, Mohamad ASR, Heukelom J, AWAN MJ, Garden AS, Gunn GB, Rosenthal DI, Fuller CD. Primary Tumor and Nodal Regression Rates.: The Prognostic Value of Volumetric Image Guided Radiation Therapy for Head and Neck Cancer. American Society of Radiation Oncology. September 2016 19. AWAN M, Lavertu P, Zender C, Rezaee R, Fowler N, Gibson M, Wasman J, Faulhaber P, Yao, M. Post treatment PET/CT and p16 status for Neck Management in Locally Advanced Head and Neck Cancer after Definitive Chemoradiation. American Society of Radiation Oncology, September 2016 20. AWAN M, Zakem S, Ward M, Machtay M, Riaz N, Caudell ], Dunlap N, Isrow D, Dault J, Higgins K, Beitler ], Siddiqui F, Trotti A, Lee N, Koyfman S, Heron D, Yao M. Re-irradiation Outcomes After

10 / 11 Upfront Larynx Preservation or Total Laryngectomy: A Multi-institutional Analysis. American Society of Radiation Oncology, September 2016. 21. Vargo J, Ward M, Caudell ], Riaz N, Dunlap N, Isrow D, Zakem S, Dault J, AWAN M, Higgins K, Beitler, Yao M, Machtay M, Siddiqui F, Trotti A, Lee N, Koyfman S, Heron D. Optimal Treatment Selection of SBRT and IMRT for Re-Irradiation of Head and Neck Cancer: A Multi-Institution Comparison. American Society of Radiation Oncology, September 2016. 22. Ward M, Riaz N, Caudell ], Dunlap N, Isrow D, Zakem S, Dault J, AWAN M, Vargo J, Heron D, Higgins K, Beitler J, Yao M, Machtay M, Siddiqui F, Trotti A, Lee N, Koyfman S. Multi-Institution Analysis of IMRT-based Re-Irradiation for Head and Neck Cancer: Prognostic Factors and Recursive Partitioning Analysis for Overall Survival. American Society of Radiation Oncology, September 2016. 23. AWAN, M, David Wittman, Eric Paulson, Dan Eastwood, Anjishnu Banerjee, Leou Ismael Banla, Christopher Schultz, Xinfeng Chen, Eenas Omari, Michael Straza, Allen Li, Beth Erickson, William Hall. Quantification and Dosimetric Impact of Normal Organ Motion during Adaptive Radiation Therapy Plan Verification using a 1.5 Tesla Magnetic Resonance Equipped Linear Accelerator (MR Linac), ASTRO Annual Meeting, 10/2021

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