11-PN-11.Pdf
Total Page:16
File Type:pdf, Size:1020Kb
Load more
Recommended publications
-
Socity the Physiologicalsociety Newsletter
p rVI i~ ne Pal Newsette Socity The PhysiologicalSociety Newsletter Contents 1 Physiological Sciences at Oxford - Clive Ellory 2 Neuroscience Research at Monash University - Uwe Proske 4 Committee News 4 Grants for IUPS Congress, Glasgow, 1993 4 COPUS - Committee on the Public Understanding of Science 4 Nominations for election to Membership 5 Computers in Teaching Initiative 5 Membership Subscriptions for 1993 5 Benevolent Fund 6 Wellcome Prize Lecturer 6 Retiring Committee Members 8 Letters & Reports 8 Society's Meetings 9 Animal Research - Speaking in Schools 9 Colin Blakemore - FRS 9 Happy 80th Birthday 10 Talking Point in the Biological Sciences - Simon Brophy,RDS 11 Chance & Design 11 Views 11 Muscular Dystrophy Group - SarahYates 14 The Multiple Sclerosis Society - John Walford 14 British Diabetic Association - Moira Murphy 15 Biomedical Research in the SERC - Alan Thomas 16 Cancer Research Campaign - TA Hince 18 The Wellcome Trust - JulianJack 22 Articles 22 Immunosuppression in Multiple Sclerosis - A N Davison 23 Hypoxia - a regulator of uterine contractions in labour? - Susan Wray 25 Pregnancy and the vascular endothelium - Lucilla Poston 28 Society Sponsored Events 28 IUPS Congress 93, list of themes 32 Notices 35 Tear-Out Forms 35 Affiliates 37 Grey Book Updates Administrations & Publications Office, P 0 Box 506, Oxford, OXI 3XE Tel: (0865) 798498 Fax: (0865) 798092 Produced by Kwabena Appenteng, Heather Dalitz and Clare Haigh The PhysiofogicafSociety 9ewsfetter Physiological Sciences at Oxford The two year interval since the last meeting of the Society in Lecturer in the department for some time, has been appointed to Oxford corresponds with the time I have been standing in for a university lectureship, in association with Balliol College. -
The Use of Non-Human Primates in Research in Primates Non-Human of Use The
The use of non-human primates in research The use of non-human primates in research A working group report chaired by Sir David Weatherall FRS FMedSci Report sponsored by: Academy of Medical Sciences Medical Research Council The Royal Society Wellcome Trust 10 Carlton House Terrace 20 Park Crescent 6-9 Carlton House Terrace 215 Euston Road London, SW1Y 5AH London, W1B 1AL London, SW1Y 5AG London, NW1 2BE December 2006 December Tel: +44(0)20 7969 5288 Tel: +44(0)20 7636 5422 Tel: +44(0)20 7451 2590 Tel: +44(0)20 7611 8888 Fax: +44(0)20 7969 5298 Fax: +44(0)20 7436 6179 Fax: +44(0)20 7451 2692 Fax: +44(0)20 7611 8545 Email: E-mail: E-mail: E-mail: [email protected] [email protected] [email protected] [email protected] Web: www.acmedsci.ac.uk Web: www.mrc.ac.uk Web: www.royalsoc.ac.uk Web: www.wellcome.ac.uk December 2006 The use of non-human primates in research A working group report chaired by Sir David Weatheall FRS FMedSci December 2006 Sponsors’ statement The use of non-human primates continues to be one the most contentious areas of biological and medical research. The publication of this independent report into the scientific basis for the past, current and future role of non-human primates in research is both a necessary and timely contribution to the debate. We emphasise that members of the working group have worked independently of the four sponsoring organisations. Our organisations did not provide input into the report’s content, conclusions or recommendations. -
Reporting the Implementation of the Three Rs in European Primate and Mouse Research Papers: Are We Making Progress?
ATLA 38, 495–517, 2010 495 Reporting the Implementation of the Three Rs in European Primate and Mouse Research Papers: Are We Making Progress? Katy Taylor British Union for the Abolition of Vivisection, London, UK Summary — It is now more than 20 years since both Council of Europe Convention ETS123 and EU Directive 86/609?EEC were introduced, to promote the implementation of the Three Rs in animal experi- mentation and to provide guidance on animal housing and care. It might therefore be expected that reports of the implementation of the Three Rs in animal research papers would have increased during this period. In order to test this hypothesis, a literature survey of animal-based research was conducted. A ran- domly-selected sample from 16 high-profile medical journals, of original research papers arising from European institutions that featured experiments which involved either mice or primates, were identified for the years 1986 and 2006 (Total sample = 250 papers). Each paper was scored out of 10 for the incidence of reporting on the implementation of Three Rs-related factors corresponding to Replacement (justification of non-use of non-animal methods), Reduction (statistical analysis of the number of animals needed) and Refinement (housing aspects, i.e. increased cage size, social housing, enrichment of cage environment and food; and procedural aspects, i.e. the use of anaesthesia, analgesia, humane endpoints, and training for procedures with positive reinforcement). There was no significant increase in overall reporting score over time, for either mouse or primate research. By 2006, mouse research papers scored an average of 0 out of a possible 10, and primate research papers scored an average of 1.5. -
Harnessing Opportunities in Non-Animal Asthma Research for a 21St-Century Science
WellBeing International WBI Studies Repository 11-2011 Harnessing Opportunities in Non-Animal Asthma Research for a 21st-Century Science Gemma L. Buckland Humane Society International Follow this and additional works at: https://www.wellbeingintlstudiesrepository.org/acwp_arte Part of the Bioethics and Medical Ethics Commons, Laboratory and Basic Science Research Commons, and the Research Methods in Life Sciences Commons Recommended Citation Buckland, G. L. (2011). Harnessing opportunities in non-animal asthma research for a 21st-century science. Drug discovery today, 16(21), 914-927. This material is brought to you for free and open access by WellBeing International. It has been accepted for inclusion by an authorized administrator of the WBI Studies Repository. For more information, please contact [email protected]. Harnessing opportunities in non-animal asthma research for a 21st-century science Gemma L. Buckland, Humane Society International CITATION Buckland, G. L. (2011). Harnessing opportunities in non-animal asthma research for a 21st-century science. Drug discovery today, 16(21), 914-927. ABSTRACT The incidence of asthma is on the increase and calls for research are growing, yet asthma is a disease that scientists are still trying to come to grips with. Asthma research has relied heavily on animal use; however, in light of increasingly robust in vitro and computational models and the need to more fully incorporate the ‘Three Rs’ principles of Replacement, Reduction and Refinement, is it time to reassess the asthma research paradigm? Progress in non-animal research techniques is reaching a level where commitment and integration are necessary. Many scientists believe that progress in this field rests on linking disciplines to make research directly translatable from the bench to the clinic; a ‘21st-century’ scientific approach to address age-old questions. -
Service History July 2012 AGM - September 2018 AGM
Service History July 2012 AGM - September 2018 AGM The information in this Service History is true and complete to the best of The Society’s knowledge. If you are aware of any errors please let the Governance and Risk Manager know by email: [email protected] Service History Index DATES PAGE # 5 July 2012 – 24 July 2013 Page 1 24 July 2013 – 1 July 2014 Page 14 1 July 2014 – 7 July 2015 Page 28 7 July 2015 – 31 July 2016 Page 42 31 July 2016 – 12 July 2017 Page 60 12 July 2017 – 16 September 2018 Page 82 Service History: July 2012 AGM – Sept 2018 AGM Introduction Up until 2006 the service history of The Society’s members was captured in Grey Books. It was also documented between 1990-2013 in The Society’s old database iMIS, which will be migrated to the CRM member directory adopted in 2016. This document collates missing service history data from July 2012 to September 2018. Grey Books were relaunched as ‘Grey Records’ in 2019 beginning with the period from the September AGM 2018 up until July AGM 2019. There will now be a Grey Record published every year reflecting the previous year’s service history. The Grey Record will now showcase service history from Member Forum to Member Forum (typically held in the Winter). 5 July 2012 – 24 July 2013 Honorary Officers (and Trustees) POSITION NAME President Jonathan Ashmore Deputy President Richard Vaughan-Jones Honorary Treasurer Rod Dimaline Education & Outreach Committee Chair Blair Grubb Meetings Committee Chair David Wyllie Policy Committee Chair Mary Morrell Membership & Grants Committee -
APVMA Comments on Animal Welfare Policy
APVMA Comments on animal welfare policy Dangers of relying on animal experiments to determine human reactions. It has already been widely acknowledged that extrapolation from animals to humans can and does result in dangerously misleading outcomes. Species differences occur in respect of anatomy, the structure and function of organs, metabolism of toxins, rates of detoxification and protein binding, absorption of chemicals, mechanisms of DNA repair and lifespan, and more. So if such differences can occur between similar species then it’s negligent to extrapolate from say a rat to a human – two totally different species with a totally different genetic make-up. Another major difference is in the regulation of our genes. A mouse and a human for example, may share 99% of the same genes, however they are regulated differently. Both a mouse and a human have the same gene that enables us to grow a tail. In the case of a mouse that gene is “turned on”, but in humans that gene is “turned off.” The argument that we share a large proportion of genes with another species cannot therefore be used as a reason for selecting a particular animal model to predict human responses. Researchers often claim that animals are used because they need to test in a living system rather than on isolated cells or tissue, however an entire living system creates more variables which can further affect the outcome of any results. A point of interest is that most animal models used in toxicity testing have never been formally validated.1 Regulatory bodies often argue that alternative non-animal tests cannot be relied upon due to them not having been validated. -
The Failure of the Three R's and the Future of Animal Experimentation
University of Chicago Legal Forum Volume 2006 | Issue 1 Article 7 Reduce, Refine, Replace: The aiF lure of the Three R's and the Future of Animal Experimentation Darian M. Ibrahim [email protected] Follow this and additional works at: http://chicagounbound.uchicago.edu/uclf Recommended Citation Ibrahim, Darian M. () "Reduce, Refine, Replace: The aiF lure of the Three R's and the Future of Animal Experimentation," University of Chicago Legal Forum: Vol. 2006: Iss. 1, Article 7. Available at: http://chicagounbound.uchicago.edu/uclf/vol2006/iss1/7 This Article is brought to you for free and open access by Chicago Unbound. It has been accepted for inclusion in University of Chicago Legal Forum by an authorized administrator of Chicago Unbound. For more information, please contact [email protected]. Reduce, Refine, Replace: The Failure of the Three R's and the Future of Animal Experimentation DarianM Ibrahimt The debate in animal ethics is defined by those who advocate the regulation of animal use and those who advocate its aboli- tion.' The animal welfare approach, which focuses on regulating animal use, maintains that humans have an obligation to treat animals "humanely" but may use them for human purposes.2 The animal rights approach, which focuses on abolishing animal use, argues that animals have inherent moral value that is inconsis- tent with us treating them as property.3 The animal welfare approach is the dominant model of ani- mal advocacy in the United States.4 Animal experimentation provides a fertile ground for testing this model because a unique confluence of factors make experimentation appear susceptible to meaningful regulation. -
Smutty Alchemy
University of Calgary PRISM: University of Calgary's Digital Repository Graduate Studies The Vault: Electronic Theses and Dissertations 2021-01-18 Smutty Alchemy Smith, Mallory E. Land Smith, M. E. L. (2021). Smutty Alchemy (Unpublished doctoral thesis). University of Calgary, Calgary, AB. http://hdl.handle.net/1880/113019 doctoral thesis University of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission. Downloaded from PRISM: https://prism.ucalgary.ca UNIVERSITY OF CALGARY Smutty Alchemy by Mallory E. Land Smith A THESIS SUBMITTED TO THE FACULTY OF GRADUATE STUDIES IN PARTIAL FULFILMENT OF THE REQUIREMENTS FOR THE DEGREE OF DOCTOR OF PHILOSOPHY GRADUATE PROGRAM IN ENGLISH CALGARY, ALBERTA JANUARY, 2021 © Mallory E. Land Smith 2021 MELS ii Abstract Sina Queyras, in the essay “Lyric Conceptualism: A Manifesto in Progress,” describes the Lyric Conceptualist as a poet capable of recognizing the effects of disparate movements and employing a variety of lyric, conceptual, and language poetry techniques to continue to innovate in poetry without dismissing the work of other schools of poetic thought. Queyras sees the lyric conceptualist as an artistic curator who collects, modifies, selects, synthesizes, and adapts, to create verse that is both conceptual and accessible, using relevant materials and techniques from the past and present. This dissertation responds to Queyras’s idea with a collection of original poems in the lyric conceptualist mode, supported by a critical exegesis of that work. -
Targeting Maladaptive Plasticity After Spinal Cord Injury to Prevent the Development of Autonomic Dysreflexia
University of Kentucky UKnowledge Theses and Dissertations--Physiology Physiology 2019 TARGETING MALADAPTIVE PLASTICITY AFTER SPINAL CORD INJURY TO PREVENT THE DEVELOPMENT OF AUTONOMIC DYSREFLEXIA Khalid C. Eldahan University of Kentucky, [email protected] Author ORCID Identifier: https://orcid.org/0000-0003-1674-2386 Digital Object Identifier: https://doi.org/10.13023/etd.2019.064 Right click to open a feedback form in a new tab to let us know how this document benefits ou.y Recommended Citation Eldahan, Khalid C., "TARGETING MALADAPTIVE PLASTICITY AFTER SPINAL CORD INJURY TO PREVENT THE DEVELOPMENT OF AUTONOMIC DYSREFLEXIA" (2019). Theses and Dissertations--Physiology. 41. https://uknowledge.uky.edu/physiology_etds/41 This Doctoral Dissertation is brought to you for free and open access by the Physiology at UKnowledge. It has been accepted for inclusion in Theses and Dissertations--Physiology by an authorized administrator of UKnowledge. For more information, please contact [email protected]. STUDENT AGREEMENT: I represent that my thesis or dissertation and abstract are my original work. Proper attribution has been given to all outside sources. I understand that I am solely responsible for obtaining any needed copyright permissions. I have obtained needed written permission statement(s) from the owner(s) of each third-party copyrighted matter to be included in my work, allowing electronic distribution (if such use is not permitted by the fair use doctrine) which will be submitted to UKnowledge as Additional File. I hereby grant to The University of Kentucky and its agents the irrevocable, non-exclusive, and royalty-free license to archive and make accessible my work in whole or in part in all forms of media, now or hereafter known. -
Women Physiologists
Women physiologists: Centenary celebrations and beyond physiologists: celebrations Centenary Women Hodgkin Huxley House 30 Farringdon Lane London EC1R 3AW T +44 (0)20 7269 5718 www.physoc.org • journals.physoc.org Women physiologists: Centenary celebrations and beyond Edited by Susan Wray and Tilli Tansey Forewords by Dame Julia Higgins DBE FRS FREng and Baroness Susan Greenfield CBE HonFRCP Published in 2015 by The Physiological Society At Hodgkin Huxley House, 30 Farringdon Lane, London EC1R 3AW Copyright © 2015 The Physiological Society Foreword copyright © 2015 by Dame Julia Higgins Foreword copyright © 2015 by Baroness Susan Greenfield All rights reserved ISBN 978-0-9933410-0-7 Contents Foreword 6 Centenary celebrations Women in physiology: Centenary celebrations and beyond 8 The landscape for women 25 years on 12 "To dine with ladies smelling of dog"? A brief history of women and The Physiological Society 16 Obituaries Alison Brading (1939-2011) 34 Gertrude Falk (1925-2008) 37 Marianne Fillenz (1924-2012) 39 Olga Hudlická (1926-2014) 42 Shelagh Morrissey (1916-1990) 46 Anne Warner (1940–2012) 48 Maureen Young (1915-2013) 51 Women physiologists Frances Mary Ashcroft 56 Heidi de Wet 58 Susan D Brain 60 Aisah A Aubdool 62 Andrea H. Brand 64 Irene Miguel-Aliaga 66 Barbara Casadei 68 Svetlana Reilly 70 Shamshad Cockcroft 72 Kathryn Garner 74 Dame Kay Davies 76 Lisa Heather 78 Annette Dolphin 80 Claudia Bauer 82 Kim Dora 84 Pooneh Bagher 86 Maria Fitzgerald 88 Stephanie Koch 90 Abigail L. Fowden 92 Amanda Sferruzzi-Perri 94 Christine Holt 96 Paloma T. Gonzalez-Bellido 98 Anne King 100 Ilona Obara 102 Bridget Lumb 104 Emma C Hart 106 Margaret (Mandy) R MacLean 108 Kirsty Mair 110 Eleanor A. -
From Guinea Pig to Computer Mouse
International Network for Humane Education from guinea pig to computer mouse alternative methods for a progressive, humane education Nick Jukes Mihnea Chiuia InterNICHE Foreword by Gill Langley Second edition, revised and expanded B from guinea pig to computer mouse alternative methods for a progressive, humane education alternative methods for a progressive, humane education 22nd editionedition Nick Jukes, BSc MihneaNick Jukes, Chiuia, BSc MD Mihnea Chiuia, MD InterNICHE B The views expressed within this book are not necessarily those of the funding organisations, nor of all the contributors Cover image (from left to right): self-experimentation physiology practical, using Biopac apparatus (Lund University, Sweden); student-assisted beneficial surgery on a canine patient (Murdoch University, Australia); virtual physiology practical, using SimMuscle software (University of Marburg, Germany) 2nd edition Published by the International Network for Humane Education (InterNICHE) InterNICHE 2003- 2006 © Minor revisions made February 2006 InterNICHE 42 South Knighton Road Leicester LE2 3LP England tel/ fax: +44 116 210 9652 e-mail: [email protected] www.interniche.org Design by CDC (www.designforcharities.org) Printed in England by Biddles Ltd. (www.biddles.co.uk) Printed on 100% post-consumer recycled paper: Millstream 300gsm (cover), Evolve 80gsm (text) ISBN: 1-904422-00-4 British Library Cataloguing-in-Publication Data A catalogue record for this book is available from the British Library B iv Contributors Jonathan Balcombe, PhD Physicians Committee for Responsible Medicine (PCRM), USA Hans A. Braun, PhD Institute of Physiology, University of Marburg, Germany Gary R. Johnston, DVM, MS Western University of Health Sciences College of Veterinary Medicine, USA Shirley D. Johnston, DVM, PhD Western University of Health Sciences College of Veterinary Medicine, USA Amarendhra M. -
Action to End Animal Toxicity Testing
TH E WA Y FO R W A R D ACTION TO END ANIMAL TOXICITY TESTING REPORT COMPILED FOR THE BUAV BY The British Union for the European Coalition to DR GILL LANGLEY MA, PhD (CANTAB), MIBiol, CBiol Abolition of Vivisection End Animal Experiments Fo r e w o r d INTRODUCING THE EUROPEAN COALITION AND THE BUAV ACTION TO END ANIMAL TOXICITY TESTING The European Coalition to End Animal Experiments, (hereafter ‘the European Animal based toxicity tests cause massive suffering and are of dubious scientific Coalition’), is Europe’s leading alliance of animal protection organisations who have value; their credibility is based on established use rather than reliability or predictive come together to campaign for effective and long-lasting change for laboratory value.i animals. Formed in 1990 by animal groups across Europe, the Coalition now represents members across member states of the European Union plus a range of Testing programmes (such as the one proposed in the European Commission’s White international observer groups drawing together organisations with a range of Paper on a Future Chemicals Policy) could drastically increase the number of animals legislative, scientific and political expertise. Its membership base is currently used in toxicity experiments, or – with sufficient political will – can be used as an expanding to include those member groups in EU accession countries. Current opportunity to bring non-animal tests into use. Observer/Member groups of the European Coalition are as follows: This report demonstrates that animal tests can be replaced with modern, humane Members: ADDA (Spain); Animal Rights Sweden; Animalia (Finland); BUAV (UK); alternatives.