PRODUCT INFORMATION D-(+)- Item No. 16493

CAS Registry No.: 453-17-8 Formal Name: (2R)-2,3-dihydroxy-propanal Synonyms: D-Glyceraldehyde, D-Glycerose, NSC 91534 MF: C H O CHO 3 6 3 HO FW: 90.1 Purity: ≥85% OH Supplied as: A neat oil Storage: -20°C Stability: ≥2 years Information represents the product specifications. Batch specific analytical results are provided on each certificate of analysis.

Laboratory Procedures

D-(+)-Glyceraldehyde is supplied as a neat oil. A stock solution may be made by dissolving the D-(+)-glyceraldehyde in the solvent of choice. D-(+)-Glyceraldehyde is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide, which should be purged with an inert gas. The solubility of D-(+)-glyceraldehyde in these solvents is approximately 30 mg/ml. Further dilutions of the stock solution into aqueous buffers or isotonic saline should be made prior to performing biological experiments. Ensure that the residual amount of organic solvent is insignificant, since organic solvents may have physiological effects at low concentrations. Organic solvent-free aqueous solutions of D-(+)-glyceraldehyde can be prepared by directly dissolving the neat oil in aqueous buffers. The solubility of D-(+)-glyceraldehyde in PBS, pH 7.2, is approximately 10 mg/ml. We do not recommend storing the aqueous solution for more than one day.

Description

D-(+)-Glyceraldehyde is an intermediate in metabolism. It is phosphorylated by triose kinase to produce D-glyceraldehyde 3-phosphate, an intermediate in , gluconeogenesis, , and other metabolic pathways.1-3

References

1. Ronimus, R.S. and Morgan, H.W. Distribution and phylogenies of enzymes of the Embden-Meyerhof- Parnas pathway from archaea and hyperthermophilic bacteria support a gluconeogenic origin of metabolism. Archaea 1(3), 199-221 (2003). 2. Sullivan, D.T., MacIntyre, R., Fuda, N., et al. Analysis of glycolytic enzyme co-localization in Drosophila flight muscle. J. Exp. Biol. 206, 2031-2038 (2003). 3. Wolosiuk, R.A., Ballicora, M.A., and Hagelin, K. The reductive phosphate cycle for photosynthetic CO2 assimilation: Enzyme modulation. FEBS J. 7, 622-637 (1993).

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