Drug-Target Pairs: R8 1

Drug-target pairs: R8 1

7512 Target 5127 DB03161 7520 Target 3460 DB02900 7528 Target 2503 DB02007

Q8GIQ0 STRSU Thymidine-5’ MPRI BOVIN Alpha-D-Mann ALGC PSEAE Alpha-D-Gluc -Dipho.. ose-6-.. ose-6-..

DTDP-4- Cation- Phosphomannomutase/phosphoglucomutase dehydrorhamnose independent 3,5-epimerase mannose-6- phosphate receptor precursor

7513 Target 5127 DB03751 7521 Target 2595 DB02007 7529 Target 2503 DB02900

Q8GIQ0 STRSU 2’deoxy-Thym PYGM RABIT Alpha-D-Gluc ALGC PSEAE Alpha-D-Mann idine-.. ose-6-.. ose-6-..

DTDP-4- Glycogen phos- Phosphomannomutase/phosphoglucomutase dehydrorhamnose phorylase, muscle 3,5-epimerase form

7514 Target 822 DB02007 7522 Target 2595 DB02843 7530 Target 2503 DB02843

ALDR HUMAN Alpha-D-Gluc PYGM RABIT Alpha-D-Gluc ALGC PSEAE Alpha-D-Gluc ose-6-.. ose-1-.. ose-1-..

Aldose reductase Glycogen phos- Phosphomannomutase/phosphoglucomutase phorylase, muscle form

7515 Target 2856 DB03951 7523 Target 2595 DB04195 7531 Target 2503 DB02867

GNPI HUMAN 16g PYGM RABIT Heptulose-2- ALGC PSEAE D-Mannose 1- Phosph.. Phosph..

Glucosamine- Glycogen phos- Phosphomannomutase/phosphoglucomutase 6-phosphate phorylase, muscle isomerase form

7516 Target 2427 DB03111 7524 Target 2595 DB02604 7532 Target 294 DB02557

FHUA ECOLI Glucosamine PYGM RABIT 2-Deoxy-Gluc NEP HUMAN Phosphoramid 1-Phos.. ose-6-.. on..

Ferrichrome-iron Glycogen phos- Neprilysin receptor precursor phorylase, muscle form

7517 Target 2427 DB02865 7525 Target 3371 DB02835 7533 Target 4597 DB02976

FHUA ECOLI Glucosamine PGM1 RABIT Alpha-D-Gluc P96945 NEIME Uridine-5’-M 4-Phos.. ose 1,.. onopho..

Ferrichrome-iron Phosphoglucomutase- Glycosyl trans- receptor precursor 1 ferase

7518 Target 2630 DB04122 7526 Target 3371 DB04397 7534 Target 4896 DB02976

G6PD LEUME Beta-D-Gluco PGM1 RABIT Alpha-D-Gluc Q93EK7 NEIME Uridine-5’-M se-6-P.. ose-1-.. onopho..

Glucose-6- Phosphoglucomutase- LgtC phosphate 1 1-dehydrogenase

7519 Target 2439 DB02007 7527 Target 3101 DB02843 7535 Target 3120 DB04482

OTSA ECOLI Alpha-D-Gluc AGP ECOLI Alpha-D-Gluc KDSB HAEIN Cmp-2-Keto-3 ose-6-.. ose-1-.. -Deoxy..

Alpha,alpha- Glucose-1- 3-deoxy-manno- trehalose- phosphatase octulosonate phosphate precursor cytidylyltrans- synthase [UDP- ferase forming] Drug-target pairs: R8 2

7536 Target 3461 DB03397 7544 Target 1881 DB02007 7552 Target 5419 DB03721

GALE ECOLI Uridine-Diph HXK1 HUMAN Alpha-D-Gluc O44049 TRYRA O-Sialic Aci osphat.. ose-6-.. d..

UDP-glucose Hexokinase-1 Sialidase 4-epimerase

7537 Target 3461 DB02421 7545 Target 2375 DB01774 7553 Target 3218 DB03721

GALE ECOLI Uridine-5’-D HLDD ECOLI Adenosine-5’ NANH VIBCH O-Sialic Aci iphosp.. -Monop.. d..

UDP-glucose ADP-L-glycero-D- Sialidase precur- 4-epimerase manno-heptose-6- sor epimerase

7538 Target 3461 DB04355 7546 Target 3407 DB02485 7554 Target 5417 DB03721

GALE ECOLI Uridine-5’-M NEUA RAT Cytidine-5’- P93248 9FABA O-Sialic Aci onopho.. Monoph.. d..

UDP-glucose N- Lectin 4-epimerase acylneuraminate cytidylyltrans- ferase

7539 Target 3461 DB04097 7547 Target 3137 DB03481 7555 Target 3546 DB04265

GALE ECOLI Uridine-5’-D FAE METEX 5,10-Dimethy NANH MICVI Beta-Sialic iphosp.. lene T.. Acid..

UDP-glucose Formaldehyde- Sialidase precur- 4-epimerase activating sor enzyme

7540 Target 3672 DB03041 7548 Target 4857 DB03721 7556 Target 4826 DB04282

UDG STRPY Udp-Glucuron ZA2G HUMAN O-Sialic Aci Q9XEI3 HORVD 2-Deoxy-2flu ic Aci.. d.. oro-Gl..

UDP-glucose Zinc-alpha-2- Beta-D-glucan ex- 6-dehydrogenase glycoprotein ohydrolase isoen- zyme ExoI

7541 Target 3672 DB01713 7549 Target 3547 DB03721 7557 Target 3480 DB04483

UDG STRPY Udp-Alpha-D- ETXB STAAU O-Sialic Aci MANA PSEFL 2-Deoxy-2-Fl Xylopy.. d.. uoro-B..

UDP-glucose Enterotoxin type Mannan endo-1,4- 6-dehydrogenase B precursor beta-mannosidase precursor

7542 Target 3439 DB02470 7550 Target 5418 DB03721 7558 Target 3480 DB04084

GMHA PSEAE D-Glycero-D- Q64823 9ADEN O-Sialic Aci MANA PSEFL 2-Deoxy-2-Fl Mannop.. d.. uoro-A..

Phosphoheptose Fiber protein Mannan endo-1,4- isomerase beta-mannosidase precursor

7543 Target 2393 DB02007 7551 Target 5414 DB03721 7559 Target 2876 DB02595

GLVA BACSU Alpha-D-Gluc Q64822 9ADEN O-Sialic Aci MLTB ECOLI Bulgecin A ose-6-.. d..

Maltose-6’- Fiber protein Membrane-bound phosphate lytic murein glucosidase transglycosylase B precursor Drug-target pairs: R8 3

7560 Target 1525 DB03959 7568 Target 3289 DB04282 7576 Target 2999 DB03109

FGF2 HUMAN N,O6-Disulfo BGLA PAEPO 2-Deoxy-2flu CHIA SERMA N-Acetyl-D-A -Gluco.. oro-Gl.. llosam..

Heparin-binding Beta-glucosidase Chitinase A pre- growth factor 2 A cursor precursor

7561 Target 3626 DB03740 7569 Target 3289 DB02658 7577 Target 2999 DB04628

PDAA BACSU 2-(Acetylami BGLA PAEPO 2,4-Dinitrop CHIA SERMA Allosamidin no)-2-.. henyl ..

Probable Beta-glucosidase Chitinase A pre- polysaccharide A cursor deacetylase pdaA precursor

7562 Target 4785 DB03740 7570 Target 4656 DB04282 7578 Target 4863 DB03740

IGHG1 HUMAN 2-(Acetylami MYRA SINAL 2-Deoxy-2flu EXG1 YEAST 2-(Acetylami no)-2-.. oro-Gl.. no)-2-..

Ig gamma-1 chain Myrosinase MA1 Glucan 1,3- C region beta-glucosidase I/II

7563 Target 3016 DB03109 7571 Target 3747 DB04282 7579 Target 1682 DB03109

CHLY HEVBR N-Acetyl-D-A Q54331 STRLI 2-Deoxy-2flu CHIT1 HUMAN N-Acetyl-D-A llosam.. oro-Gl.. llosam..

Hevamine-A pre- Cellulase B pre- Chitotriosidase-1 cursor [Includes: cursor precursor Chitinase

7564 Target 2857 DB03013 7572 Target 2427 DB01296 7580 Target 2592 DB02228

B4GT1 BOVIN Di(N-Acetyl- FHUA ECOLI Glucosamine BGAL ECOLI 2-Fluoro-2-D D-Gluc.. eoxy-B..

Approved Beta-1,4- Ferrichrome-iron Beta- galactosyltransferase receptor precursor galactosidase 1

7565 Target 287 DB00141 7573 Target 2427 DB03548 7581 Target 2592 DB04382

B4GT1 HUMAN N-Acetyl-D-g FHUA ECOLI 3-Deoxy-D-Ma BGAL ECOLI 2-Deoxy-Beta lucosa.. nno-Oc.. -D-Gal..

Approved Beta-1,4- Ferrichrome-iron Beta- galactosyltransferase receptor precursor galactosidase 1

7566 Target 4666 DB03740 7574 Target 2887 DB04628 7582 Target 3090 DB01296

Q9HYN5 PSEAE 2-(Acetylami CHIB SERMA Allosamidin CHIS BACCI Glucosamine no)-2-..

Approved Fucose-binding Chitinase B pre- Chitosanase lectin PA-IIL cursor precursor

7567 Target 3061 DB03109 7575 Target 2887 DB03109 7583 Target 2519 DB04426

CHI1 COCPO N-Acetyl-D-A CHIB SERMA N-Acetyl-D-A MBL2 RAT Alpha-Methyl llosam.. llosam.. -N-Ace..

Endochitinase 1 Chitinase B pre- Mannose-binding precursor cursor protein C precursor Drug-target pairs: R8 4

7584 Target 4416 DB01872 7592 Target 2430 DB01872 7600 Target 400 DB01109

P84141 ARTAU Acetylgalact CSLB PEDHE Acetylgalact FA9 HUMAN Heparin osamin.. osamin..

Approved Chondroitinase Chondroitinase B Coagulation fac- precursor tor IX precursor

7585 Target 4012 DB00141 7593 Target 2430 DB04492 7601 Target 2324 DB03721

B4GT4 HUMAN N-Acetyl-D-g CSLB PEDHE 2-(Acetylami BXB CLOBO O-Sialic Aci lucosa.. no)-2-.. d..

Approved Beta-1,4- Chondroitinase B Botulinum neuro- galactosyltransferase precursor toxin type B pre- 4 cursor

7586 Target 2549 DB03740 7594 Target 2581 DB01872 7602 Target 3629 DB04265

ACES TORCA 2-(Acetylami CSLA PEDHE Acetylgalact ENAN BPK1F Beta-Sialic no)-2-.. osamin.. Acid..

Acetylcholinesterase Chondroitinase Endo-N- precursor AC precursor acetylneuraminidase

7587 Target 2575 DB04426 7595 Target 2581 DB02186 7603 Target 3629 DB03721

MRC1 MOUSE Alpha-Methyl CSLA PEDHE N-Acetyl-D-G ENAN BPK1F O-Sialic Aci -N-Ace.. alacto.. d..

Macrophage Chondroitinase Endo-N- mannose receptor AC precursor acetylneuraminidase 1 precursor

7588 Target 2575 DB01872 7596 Target 1588 DB00778 7604 Target 3499 DB04355

MRC1 MOUSE Acetylgalact MDR1 HUMAN Roxithromyci GGTA1 BOVIN Uridine-5’-M osamin.. n.. onopho..

Approved Macrophage Multidrug re- N- mannose receptor sistance protein acetyllactosaminide 1 precursor 1 alpha-1,3- galactosyltransferase

7589 Target 4787 DB03740 7597 Target 2676 DB03965 7605 Target 3322 DB04226

ENV SIVMK 2-(Acetylami NRAM IATOK Fucose AMYG ASPSH Dihydro-Acar no)-2-.. bose..

Envelope glyco- Neuraminidase Glucoamylase pre- protein gp160 cursor

7590 Target 2485 DB01872 7598 Target 2676 DB02944 7606 Target 2723 DB03721

HYSA STRPN Acetylgalact NRAM IATOK Alpha-D-Mann CHTB VIBCH O-Sialic Aci osamin.. ose.. d..

Hyaluronate lyase Neuraminidase Cholera entero- precursor toxin subunit B precursor

7591 Target 2485 DB02186 7599 Target 2324 DB02379 7607 Target 2438 DB04263

HYSA STRPN N-Acetyl-D-G BXB CLOBO Beta-D-Gluco DCOR TRYBB G418 alacto.. se..

Hyaluronate lyase Botulinum neuro- Ornithine precursor toxin type B pre- decarboxylase cursor Drug-target pairs: R8 5

7608 Target 3609 DB03740 7616 Target 3026 DB03721 7624 Target 4865 DB02944

HN NDVB 2-(Acetylami NRAM IATRA O-Sialic Aci GALT1 MOUSE Alpha-D-Mann no)-2-.. d.. ose..

Hemagglutinin- Neuraminidase Polypeptide N- neuraminidase acetylgalactosaminyltransferase 1

7609 Target 3609 DB03721 7617 Target 2570 DB01894 7625 Target 4240 DB03615

HN NDVB O-Sialic Aci TETX CLOTE 5-N-Acetyl-A PDIA1 HUMAN Ribostamycin d.. lpha-D..

Hemagglutinin- Tetanus toxin pre- Protein disulfide- neuraminidase cursor isomerase

7610 Target 2058 DB03721 7618 Target 2570 DB03721 7626 Target 2723 DB03524

LYAM3 HUMAN O-Sialic Aci TETX CLOTE O-Sialic Aci CHTB VIBCH N-(3-[4-(3-A d.. d.. mino-P..

P-selectin precur- Tetanus toxin pre- Cholera entero- sor cursor toxin subunit B precursor

7611 Target 2058 DB01109 7619 Target 2570 DB04265 7627 Target 2723 DB03235

LYAM3 HUMAN Heparin TETX CLOTE Beta-Sialic CHTB VIBCH N-(3-[4-(3-A Acid.. mino-P..

Approved P-selectin precur- Tetanus toxin pre- Cholera entero- sor cursor toxin subunit B precursor

7612 Target 2058 DB02612 7620 Target 1244 DB00798 7628 Target 2723 DB02574

LYAM3 HUMAN 1na LRP2 HUMAN Gentamicin CHTB VIBCH BV2

Approved P-selectin precur- Low-density Cholera entero- sor lipoprotein toxin subunit B receptor-related precursor protein 2 precursor

7613 Target 1756 DB02612 7621 Target 239 DB01225 7629 Target 2723 DB04073

LYAM2 HUMAN 1na FA10 HUMAN Enoxaparin CHTB VIBCH N-(3-[4-(3-A mino-P..

Approved E-selectin precur- Coagulation Cholera entero- sor factor X precursor toxin subunit B precursor

7614 Target 1756 DB03721 7622 Target 239 DB01109 7630 Target 2723 DB02903

LYAM2 HUMAN O-Sialic Aci FA10 HUMAN Heparin CHTB VIBCH BV3 d..

Approved E-selectin precur- Coagulation Cholera entero- sor factor X precursor toxin subunit B precursor

7615 Target 5416 DB03721 7623 Target 2672 DB03122 7631 Target 2723 DB02572

COA1 POVMP O-Sialic Aci ERG7 HUMAN B-Octylgluco CHTB VIBCH BV4 d.. side..

Coat protein VP1 Lanosterol Cholera entero- synthase toxin subunit B precursor Drug-target pairs: R8 6

7632 Target 650 DB01698 7640 Target 2597 DB02007 7648 Target 5498 DB04173

AK1C3 HUMAN Rutin GLMS ECOLI Alpha-D-Gluc LAMB ECOLI Fructose ose-6-..

Aldo-keto re- Glucosamine– Maltoporin ductase family 1 fructose-6- member C3 phosphate aminotransferase [isomerizing]

7633 Target 147 DB02115 7641 Target 2484 DB02007 7649 Target 4351 DB04493

ALDH2 HUMAN Daidzin G6PI MOUSE Alpha-D-Gluc O57693 THETE Fructose-6-P ose-6-.. hospha..

Aldehyde de- Glucose-6- Glyceraldehyde- hydrogenase, phosphate 3-phosphate mitochondrial isomerase dehydrogenase precursor

7634 Target 2299 DB01673 7642 Target 3091 DB02843 7650 Target 308 DB00798

MURC HAEIN Uridine-5’-D PHSM ECOLI Alpha-D-Gluc RS12 ECOLI Gentamicin iphosp.. ose-1-..

Approved UDP-N- Maltodextrin 30S ribosomal acetylmuramate– phosphorylase protein S12 L-alanine ligase

7635 Target 2365 DB01861 7643 Target 2538 DB02007 7651 Target 308 DB00684

GAL10 YEAST Glucose-Urid BGLT THEMA Alpha-D-Gluc RS12 ECOLI Tobramycin ine-C1.. ose-6-..

Approved GAL10 bifunc- 6-phospho-beta- 30S ribosomal tional protein glucosidase protein S12 [Includes: bglT UDP-glucose 4-epimerase

7636 Target 2857 DB03501 7644 Target 3181 DB02547 7652 Target 308 DB00919

B4GT1 BOVIN Uridine Diph GMD2 ARATH Guanosine-5’ RS12 ECOLI Spectinomyci osphat.. -Dipho.. n..

Approved Beta-1,4- GDP-mannose 4,6 30S ribosomal galactosyltransferase dehydratase 2 protein S12 1

7637 Target 5252 DB03397 7645 Target 2922 DB04551 7653 Target 308 DB00479

GLMU STRPN Uridine-Diph GLPK ECOLI Fructose-1,6 RS12 ECOLI Amikacin osphat.. -Dipho..

Approved Bifunctional pro- Glycerol kinase 30S ribosomal tein glmU protein S12

7638 Target 3367 DB04023 7646 Target 4273 DB04173 7654 Target 308 DB01172

ALGD PSEAE Guanosine 5’ Q8GSD2 9FABA Fructose RS12 ECOLI Kanamycin -(Trih..

Approved GDP-mannose 6- Lectin 30S ribosomal dehydrogenase protein S12

7639 Target 2597 DB02657 7647 Target 4846 DB04173 7655 Target 308 DB01082

GLMS ECOLI Glucosamine Q96TU3 ASPAW Fructose RS12 ECOLI Streptomycin 6-Phos..

Approved Glucosamine– Exo-inulinase 30S ribosomal fructose-6- protein S12 phosphate aminotransferase [isomerizing] Drug-target pairs: R8 7

7656 Target 308 DB00452 7664 Target 2366 DB02357 7672 Target 4367 DB02379

RS12 ECOLI Framycetin LEC GALNI Methyl-O3-(A GLKA PYRFU Beta-D-Gluco lpha-D.. se..

Approved 30S ribosomal Mannose-specific ADP-dependent protein S12 lectin precursor glucokinase

7657 Target 308 DB00994 7665 Target 2366 DB02944 7673 Target 1859 DB02944

RS12 ECOLI Neomycin LEC GALNI Alpha-D-Mann PPAP HUMAN Alpha-D-Mann ose.. ose..

Approved 30S ribosomal Mannose-specific Prostatic acid protein S12 lectin precursor phosphatase precursor

7658 Target 308 DB03615 7666 Target 2468 DB03122 7674 Target 1859 DB03965

RS12 ECOLI Ribostamycin PGH1 SHEEP B-Octylgluco PPAP HUMAN Fucose side..

30S ribosomal Prostaglandin Prostatic acid protein S12 G/H synthase 1 phosphatase precursor precursor

7659 Target 4565 DB03615 7667 Target 2468 DB02379 7675 Target 3113 DB03485

Q9R381 SALEN Ribostamycin PGH1 SHEEP Beta-D-Gluco PAO MAIZE Alpha-D-Fuco se.. se..

Aminoglycoside Prostaglandin Polyamine oxidase 6’-N- G/H synthase 1 precursor acetyltransferase precursor

7660 Target 760 DB00686 7668 Target 2468 DB02687 7676 Target 3113 DB02944

FGF1 HUMAN Pentosan Pol PGH1 SHEEP Beta-D-Manno PAO MAIZE Alpha-D-Mann ysulfa.. se.. ose..

Approved Heparin-binding Prostaglandin Polyamine oxidase growth factor 1 G/H synthase 1 precursor precursor precursor

7661 Target 4853 DB02944 7669 Target 2468 DB02944 7677 Target 3668 DB02379

IDGF2 DROME Alpha-D-Mann PGH1 SHEEP Alpha-D-Mann MALE ECOLI Beta-D-Gluco ose.. ose.. se..

Chitinase-like pro- Prostaglandin Maltose-binding tein Idgf2 G/H synthase 1 periplasmic precursor protein precursor

7662 Target 760 DB02264 7670 Target 1052 DB02944 7678 Target 3668 DB03323

FGF1 HUMAN O2-Sulfo-Glu CTLA4 HUMAN Alpha-D-Mann MALE ECOLI Maltose curoni.. ose..

Heparin-binding Cytotoxic T- Maltose-binding growth factor 1 lymphocyte periplasmic precursor protein 4 protein precursor precursor

7663 Target 2366 DB01979 7671 Target 1052 DB03965 7679 Target 3668 DB03995

LEC GALNI O1-Methyl-Ma CTLA4 HUMAN Fucose MALE ECOLI Cyclo-Hepta- nnose.. Amylos..

Mannose-specific Cytotoxic T- Maltose-binding lectin precursor lymphocyte periplasmic protein 4 protein precursor precursor Drug-target pairs: R8 8

7680 Target 4193 DB02944 7688 Target 5474 DB03965 7696 Target 5552 DB02379

ANPRC HUMAN Alpha-D-Mann FGF9 RAT Fucose LEC PEA Beta-D-Gluco ose.. se..

Atrial natriuretic Glia-activating Lectin peptide clearance factor receptor

7681 Target 4193 DB03965 7689 Target 4849 DB02944 7697 Target 2668 DB02100

ANPRC HUMAN Fucose Q9ZQY5 HELTU Alpha-D-Mann LEC1 PSOTE Alpha-methyl ose.. -D-gal..

Atrial natriuretic Lectin 1 Basic agglutinin peptide clearance receptor

7682 Target 2989 DB04473 7690 Target 3444 DB02695 7698 Target 2534 DB02100

LECF ALEAU Alpha-L-Fuco CVN NOSEL O1-Pentyl-Ma CONA CANVI Alpha-methyl se.. nnose.. -D-gal..

Fucose-specific Cyanovirin-N Concanavalin A lectin

7683 Target 2989 DB03965 7691 Target 3444 DB02944 7699 Target 2534 DB01979

LECF ALEAU Fucose CVN NOSEL Alpha-D-Mann CONA CANVI O1-Methyl-Ma ose.. nnose..

Fucose-specific Cyanovirin-N Concanavalin A lectin

7684 Target 2989 DB03283 7692 Target 2631 DB02686 7700 Target 2534 DB01642

LECF ALEAU beta-L-fucos NTPK ENTHR Undecyl-Beta CONA CANVI O1-Methyl-Gl e.. -D-Mal.. ucose..

Fucose-specific V-type sodium Concanavalin A lectin ATP synthase subunit K

7685 Target 5472 DB03965 7693 Target 3437 DB02687 7701 Target 2534 DB02944

LEC5 DOLBI Fucose LPPL HUMAN Beta-D-Manno CONA CANVI Alpha-D-Mann se.. ose..

Lectin DB58 Eosinophil Concanavalin A lysophospholipase

7686 Target 2668 DB03965 7694 Target 2745 DB03122 7702 Target 2534 DB03634

LEC1 PSOTE Fucose PYRD RAT B-Octylgluco CONA CANVI 1,3-Di(N-Pro side.. pyloxy..

Basic agglutinin Dihydroorotate Concanavalin A dehydrogenase, mitochondrial precursor

7687 Target 4673 DB03965 7695 Target 3452 DB02879 7703 Target 4661 DB02379

LEC VICVI Fucose TA47 TREPA 2,3-Di-O-Sul Q8GZD5 9ROSI Beta-D-Gluco fo-Alp.. se..

Lectin B4 47 kDa membrane Xyloglucan endo- antigen precursor transglycosylase Drug-target pairs: R8 9

7704 Target 4661 DB02687 7712 Target 5453 DB04465 7720 Target 2244 DB01651

Q8GZD5 9ROSI Beta-D-Manno LEG2 CONMY Lactose SAMP HUMAN Methyl 4,6-O se.. -[(1r)..

Xyloglucan endo- Congerin-2 Serum amyloid transglycosylase P-component precursor

7705 Target 5738 DB04680 7713 Target 4556 DB01979 7721 Target 2984 DB03122

Q9NY01 HUMAN GALACTOSE GR Q7M1T4 ARTIN O1-Methyl-Ma PA21B AGKHA B-Octylgluco EASE.. nnose.. side..

B transferase Mannose-specific Phospholipase A2, lectin KM+ basic

7706 Target 3709 DB03122 7714 Target 4556 DB02944 7722 Target 4889 DB02944

GLPF ECOLI B-Octylgluco Q7M1T4 ARTIN Alpha-D-Mann IGHE HUMAN Alpha-D-Mann side.. ose.. ose..

Glycerol uptake Mannose-specific Ig epsilon chain C facilitator protein lectin KM+ region

7707 Target 5056 DB02379 7715 Target 1719 DB01109 7723 Target 4880 DB02944

Q9RX51 DEIRA Beta-D-Gluco HPSE HUMAN Heparin MCP HUMAN Alpha-D-Mann se.. ose..

Approved Maltooligosyltrehalose Heparanase Membrane cofac- trehalohydrolase, precursor tor protein putative

7708 Target 5056 DB03323 7716 Target 3483 DB02900 7724 Target 2996 DB02944

Q9RX51 DEIRA Maltose MPRD BOVIN Alpha-D-Mann EST1 RABIT Alpha-D-Mann ose-6-.. ose..

Maltooligosyltrehalose Cation-dependent Liver car- trehalohydrolase, mannose-6- boxylesterase 1 putative phosphate precursor receptor precursor

7709 Target 2414 DB02944 7717 Target 3483 DB02755 7725 Target 1184 DB02944

QDOI ASPJA Alpha-D-Mann MPRD BOVIN 1-3 Sugar Ri IFNB HUMAN Alpha-D-Mann ose.. ng of .. ose..

Quercetin Cation-dependent Interferon beta 2,3-dioxygenase mannose-6- precursor phosphate receptor precursor

7710 Target 2414 DB02687 7718 Target 2938 DB02451 7726 Target 1184 DB02379

QDOI ASPJA Beta-D-Manno MIP BOVIN B-Nonylgluco IFNB HUMAN Beta-D-Gluco se.. side.. se..

Quercetin Lens fiber major Interferon beta 2,3-dioxygenase intrinsic protein precursor

7711 Target 3067 DB03152 7719 Target 4597 DB02065 7727 Target 2527 DB01901

AQPZ SHIFL B-2-Octylglu P96945 NEIME 4-Deoxylacto FGF1 BOVIN Sucrose Octa coside.. se.. sulfat..

Aquaporin Z Glycosyl trans- Heparin-binding ferase growth factor 1 precursor Drug-target pairs: R8 10

7728 Target 3210 DB04664 7736 Target 237 DB04679 7744 Target 2476 DB02835

CP2B4 RABIT Cyclohexyl-p BGAT HUMAN H TYPE I TRI PGMB LACLA Alpha-D-Gluc entyl-.. SACCHA.. ose 1,..

Cytochrome P450 Histo-blood group Beta- 2B4 ABO system phosphoglucomutase transferase

7729 Target 4859 DB02944 7737 Target 237 DB04678 7745 Target 2476 DB02317

ENV FSVGA Alpha-D-Mann BGAT HUMAN H TYPE II TR PGMB LACLA Alpha-D-Gala ose.. ISACCH.. ctose-..

Envelope glyco- Histo-blood group Beta- protein ABO system phosphoglucomutase transferase

7730 Target 4845 DB02944 7738 Target 237 DB04681 7746 Target 3139 DB02944

ADA33 HUMAN Alpha-D-Mann BGAT HUMAN BETA-METHYLL GUX2 TRIRE Alpha-D-Mann ose.. ACTOSI.. ose..

ADAM 33 Histo-blood group Exoglucanase 2 ABO system precursor transferase

7731 Target 1184 DB03965 7739 Target 237 DB04680 7747 Target 3139 DB02379

IFNB HUMAN Fucose BGAT HUMAN GALACTOSE GR GUX2 TRIRE Beta-D-Gluco EASE.. se..

Interferon beta Histo-blood group Exoglucanase 2 precursor ABO system precursor transferase

7732 Target 369 DB03965 7740 Target 237 DB04141 7748 Target 3139 DB01642

FA7 HUMAN Fucose BGAT HUMAN 2-Hexyloxy-6 GUX2 TRIRE O1-Methyl-Gl -Hydro.. ucose..

Coagulation Histo-blood group Exoglucanase 2 factor VII ABO system precursor precursor transferase

7733 Target 1074 DB03965 7741 Target 237 DB03965 7749 Target 4272 DB01642

UROK HUMAN Fucose BGAT HUMAN Fucose Q79G13 MYCTU O1-Methyl-Gl ucose..

Urokinase-type Histo-blood group POSSIBLE CEL- plasminogen acti- ABO system LULASE CELA1 vator precursor transferase

7734 Target 437 DB03965 7742 Target 237 DB03772 7750 Target 4272 DB02379

ELNE HUMAN Fucose BGAT HUMAN 2-Hexyloxy-6 Q79G13 MYCTU Beta-D-Gluco -Hydro.. se..

Leukocyte Histo-blood group POSSIBLE CEL- elastase precursor ABO system LULASE CELA1 transferase

7735 Target 1112 DB03965 7743 Target 2619 DB02312 7751 Target 4815 DB02772

CD59 HUMAN Fucose LACG LACLA Beta-Galacto Y1602 PYRHO Sucrose se-6-P..

CD59 glycopro- 6-phospho-beta- UPF0027 protein tein precursor galactosidase PH1602 Drug-target pairs: R8 11

7752 Target 3213 DB03281 7760 Target 5249 DB02379 7768 Target 3711 DB04062

AMYB IPOBA 2’-Deoxymalt Q7SI98 STROI Beta-D-Gluco ARAC ECOLI Beta-D-Fucos ose.. se.. e..

Beta-amylase Hydrolase Arabinose operon regulatory protein

7753 Target 2339 DB03152 7761 Target 5249 DB04465 7769 Target 3041 DB03965

TGM3 HUMAN B-2-Octylglu Q7SI98 STROI Lactose OXLA AGKRH Fucose coside..

Protein-glutamine Hydrolase L-amino-acid oxi- gamma- dase precursor glutamyltransferase E precursor

7754 Target 1943 DB02264 7762 Target 4870 DB02944 7770 Target 3065 DB03965

HGF HUMAN O2-Sulfo-Glu Q92456 TRIRE Alpha-D-Mann LEC4 GRISI Fucose curoni.. ose..

Hepatocyte Alpha- Lectin-4 growth factor galactosidase precursor

7755 Target 2705 DB02379 7763 Target 5415 DB02379 7771 Target 4830 DB03965

DMSA RHOSH Beta-D-Gluco SN MOUSE Beta-D-Gluco Q9ZB17 9LACT Fucose se.. se..

Dimethyl sul- Sialoadhesin Aldose 1- foxide reductase epimerase precursor

7756 Target 2654 DB02264 7764 Target 4873 DB02944 7772 Target 4830 DB03773

VCP VACCV O2-Sulfo-Glu GCA RAT Alpha-D-Mann Q9ZB17 9LACT 6-Deoxy-Alph curoni.. ose.. a-D-Gl..

Complement con- Ig gamma-2A Aldose 1- trol protein pre- chain C region epimerase cursor

7757 Target 3025 DB03122 7765 Target 4873 DB03965 7773 Target 4351 DB02843

F264 RAT B-Octylgluco GCA RAT Fucose O57693 THETE Alpha-D-Gluc side.. ose-1-..

6-phosphofructo- Ig gamma-2A Glyceraldehyde- 2-kinase/fructose- chain C region 3-phosphate 2,6-biphosphatase dehydrogenase 4

7758 Target 1277 DB01998 7766 Target 2663 DB03283 7774 Target 4887 DB02944

A1AT HUMAN 2-[3,4-Dihyd ACES MOUSE beta-L-fucos PGLR1 ASPAC Alpha-D-Mann roxy-2.. e.. ose..

Alpha-1- Acetylcholinesterase Polygalacturonase antitrypsin precursor 1 precursor

7759 Target 1502 DB03338 7767 Target 2663 DB03965 7775 Target 3065 DB02944

PPARD HUMAN Heptyl-Beta- ACES MOUSE Fucose LEC4 GRISI Alpha-D-Mann D-Gluc.. ose..

Peroxisome Acetylcholinesterase Lectin-4 proliferator- precursor activated receptor delta Drug-target pairs: R8 12

7776 Target 4810 DB02772 7784 Target 5247 DB02379 7792 Target 793 DB02944

Q59976 STRSQ Sucrose XYN1 BACST Beta-D-Gluco CD2 HUMAN Alpha-D-Mann se.. ose..

Beta-glucosidase Endo-1,4-beta- T-cell surface xylanase antigen CD2 precursor

7777 Target 3525 DB02379 7785 Target 2260 DB02379 7793 Target 2960 DB02379

NUDT9 HUMAN Beta-D-Gluco XYLA STRRU Beta-D-Gluco AMY2 HORVU Beta-D-Gluco se.. se.. se..

ADP-ribose Xylose isomerase Alpha-amylase pyrophosphatase, type B isozyme mitochondrial precursor precursor

7778 Target 3744 DB02379 7786 Target 2431 DB02379 7794 Target 3021 DB03989

GUNS CLOTM Beta-D-Gluco XYLA STROL Beta-D-Gluco ALSB ECOLI D-Allopyrano se.. se.. se..

Endoglucanase SS Xylose isomerase D-allose-binding precursor periplasmic protein precursor

7779 Target 5224 DB02379 7787 Target 3713 DB03122 7795 Target 4830 DB02379

MALQ THELI Beta-D-Gluco PA1 ECOLI B-Octylgluco Q9ZB17 9LACT Beta-D-Gluco se.. side.. se..

4-alpha- Phospholipase A1 Aldose 1- glucanotransferase precursor epimerase

7780 Target 5224 DB03323 7788 Target 4595 DB02061 7796 Target 4831 DB02379

MALQ THELI Maltose Q8J0K8 MELAO Cellobiose PSBP3 TOBAC Beta-D-Gluco se..

4-alpha- Cellulase Oxygen-evolving glucanotransferase enhancer protein 2-3, chloroplast

7781 Target 4808 DB04303 7789 Target 4277 DB02843 7797 Target 4630 DB02284

O68541 9GAMM 4-O-Methyl-A Q9HU22 PSEAE Alpha-D-Gluc Q8XUA5 RALSO 1-O-Methyl-A lpha-D.. ose-1-.. lpha-D..

Endoxylanase Glucose-1- Probable sugar- phosphate binding lectin thymidylyltrans- protein ferase

7782 Target 3057 DB03485 7790 Target 4872 DB02944 7798 Target 4629 DB02772

ARAF ECOLI Alpha-D-Fuco LIG2 PHACH Alpha-D-Mann Q9L5C8 ECOLI Sucrose se.. ose..

L-arabinose- Ligninase LG2 Beta-lactamase binding periplas- CTX-M-9a mic protein precursor

7783 Target 3057 DB04062 7791 Target 4858 DB02944 7799 Target 4818 DB02772

ARAF ECOLI Beta-D-Fucos PHYB ASPAW Alpha-D-Mann Q840M4 ECOLI Sucrose e.. ose..

L-arabinose- 3-phytase B Beta-lactamase binding periplas- CTX-M-27 mic protein precursor Drug-target pairs: R8 13

7800 Target 4812 DB02772 7808 Target 2384 DB01979 7816 Target 3154 DB02379

Q9L5C7 ECOLI Sucrose MBL1 RAT O1-Methyl-Ma AMY1 HORVU Beta-D-Gluco nnose.. se..

Extended- Mannose-binding Alpha-amylase spectrum protein A type A isozyme beta-lactamase precursor precursor CTX-M-14

7801 Target 3225 DB02379 7809 Target 2384 DB02837 7817 Target 5484 DB03995

SLTB BPH30 Beta-D-Gluco MBL1 RAT O4-Sulfonylg O69007 9DEIN Cyclo-Hepta- se.. alacto.. Amylos..

Shiga toxin Mannose-binding Maltogenic B-chain precursor protein A amylase precursor

7802 Target 4881 DB02944 7810 Target 2384 DB03324 7818 Target 4343 DB03323

Q9URD0 ASPOR Alpha-D-Mann MBL1 RAT Beta-Methyl- AGLA THEMA Maltose ose.. D-Gala..

Aspartic pro- Mannose-binding Alpha-glucosidase teinase II-1 protein A precursor

7803 Target 2384 DB03194 7811 Target 2681 DB02772 7819 Target 2316 DB03122

MBL1 RAT Beta-L-Methy LYSC CHICK Sucrose IMDH TRIFO B-Octylgluco l-Fuco.. side..

Mannose-binding Lysozyme C pre- Inosine-5’- protein A cursor monophosphate precursor dehydrogenase

7804 Target 2384 DB03965 7812 Target 1875 DB02379 7820 Target 4189 DB02944

MBL1 RAT Fucose SFTPD HUMAN Beta-D-Gluco AGAL HUMAN Alpha-D-Mann se.. ose..

Mannose-binding Pulmonary Alpha- protein A surfactant- galactosidase precursor associated protein A D precursor

7805 Target 2384 DB04091 7813 Target 2478 DB02772 7821 Target 4189 DB03965

MBL1 RAT Alpha-L-1-Me AMPC ECOLI Sucrose AGAL HUMAN Fucose thyl-F..

Mannose-binding Beta-lactamase Alpha- protein A precursor galactosidase precursor A

7806 Target 2384 DB02944 7814 Target 4855 DB02944 7822 Target 3154 DB03406

MBL1 RAT Alpha-D-Mann PGLR1 ASPNG Alpha-D-Mann AMY1 HORVU O1-Methyl-4- ose.. ose.. Deoxy-..

Mannose-binding Polygalacturonase- Alpha-amylase protein A 1 type A isozyme precursor precursor

7807 Target 2384 DB01818 7815 Target 2448 DB02379 7823 Target 3154 DB03599

MBL1 RAT O3-Sulfonylg GUX CELFI Beta-D-Gluco AMY1 HORVU 4-Thio-D-Glu alacto.. se.. cose..

Mannose-binding Exoglucanase/xylanase Alpha-amylase protein A precursor [In- type A isozyme precursor cludes: Exoglu- precursor canase Drug-target pairs: R8 14

7824 Target 3139 DB03584 7832 Target 2508 DB01841 7840 Target 2252 DB03584

GUX2 TRIRE 4-Deoxy-4-Th CDGT BACS0 4,6-Dideoxyg GUN5 BACAG 4-Deoxy-4-Th io-Bet.. lucose.. io-Bet..

Exoglucanase 2 Cyclomaltodextrin Endoglucanase 5A precursor glucanotransferase precursor

7825 Target 4272 DB03584 7833 Target 2523 DB01841 7841 Target 2523 DB02670

Q79G13 MYCTU 4-Deoxy-4-Th CDGT2 BACCI 4,6-Dideoxyg CDGT2 BACCI 4-Deoxy-Alph io-Bet.. lucose.. a-D-Gl..

POSSIBLE CEL- Cyclomaltodextrin Cyclomaltodextrin LULASE CELA1 glucanotrans- glucanotrans- ferase precursor ferase precursor

7826 Target 3215 DB03870 7834 Target 2541 DB01841 7842 Target 2483 DB02730

ABFA BACST Ara-Alpha(1, NEPU1 THEVU 4,6-Dideoxyg AMYP PIG 4-Methylthio 3)-Xyl.. lucose.. -Alpha..

Alpha-N- Neopullulanase 1 Pancreatic alpha- arabinofuranosidase precursor amylase precursor

7827 Target 1162 DB00452 7835 Target 2293 DB02469 7843 Target 2246 DB03584

CXCR4 HUMAN Framycetin CDGT1 BACCI 4,6-Dideoxy- GUX1 TRIRE 4-Deoxy-4-Th 4-Amin.. io-Bet..

Approved C-X-C chemokine Cyclomaltodextrin Exoglucanase 1 receptor type 4 glucanotrans- precursor ferase precursor

7828 Target 3030 DB03439 7836 Target 2440 DB03584 7844 Target 2430 DB04548

AMYS HUMAN 4,6-Dideoxy- GUNF CLOCE 4-Deoxy-4-Th CSLB PEDHE 4-Deoxy-D-Gl 4-Amin.. io-Bet.. ucuron..

Salivary alpha- Endoglucanase F Chondroitinase B amylase precursor precursor precursor

7829 Target 4513 DB03439 7837 Target 2440 DB03599 7845 Target 4274 DB03291

AMYP HUMAN 4,6-Dideoxy- GUNF CLOCE 4-Thio-D-Glu GUX6 HUMIN 4-Deoxy-4-Am 4-Amin.. cose.. ino-Be..

Pancreatic alpha- Endoglucanase F Exoglucanase-6A amylase precursor

7830 Target 2531 DB01841 7838 Target 2802 DB03188 7846 Target 4274 DB01648

AMY BACSU 4,6-Dideoxyg GUNG CLOCE 4-Thio-Beta- GUX6 HUMIN O1-Methyl-4- lucose.. D-Gluc.. Deoxy-..

Alpha-amylase Endoglucanase G Exoglucanase-6A precursor precursor

7831 Target 2564 DB01841 7839 Target 3172 DB04548 7847 Target 4274 DB03406

AMT6 BACS7 4,6-Dideoxyg HYSA STRA3 4-Deoxy-D-Gl GUX6 HUMIN O1-Methyl-4- lucose.. ucuron.. Deoxy-..

Glucan 1,4-alpha- Hyaluronate lyase Exoglucanase-6A maltohexaosidase precursor precursor Drug-target pairs: R8 15

7848 Target 4274 DB03584 7856 Target 10 DB02379 7864 Target 952 DB02944

GUX6 HUMIN 4-Deoxy-4-Th PYGL HUMAN Beta-D-Gluco DPP4 HUMAN Alpha-D-Mann io-Bet.. se.. ose..

Exoglucanase-6A Glycogen phos- Dipeptidyl pepti- phorylase, liver dase 4 form

7849 Target 2485 DB04548 7857 Target 554 DB02944 7865 Target 3491 DB02944

HYSA STRPN 4-Deoxy-D-Gl LDLR HUMAN Alpha-D-Mann DPP4 PIG Alpha-D-Mann ucuron.. ose.. ose..

Hyaluronate lyase Low-density Dipeptidyl pepti- precursor lipoprotein dase 4 receptor precursor

7850 Target 5696 DB04548 7858 Target 2246 DB01642 7866 Target 4787 DB04473

Q9KWU1 9SPHN 4-Deoxy-D-Gl GUX1 TRIRE O1-Methyl-Gl ENV SIVMK Alpha-L-Fuco ucuron.. ucose.. se..

Alginate lyase Exoglucanase 1 Envelope glyco- precursor protein gp160

7851 Target 3327 DB02670 7859 Target 2246 DB02379 7867 Target 4787 DB02944

ISWI DROME 4-Deoxy-Alph GUX1 TRIRE Beta-D-Gluco ENV SIVMK Alpha-D-Mann a-D-Gl.. se.. ose..

Chromatin remod- Exoglucanase 1 Envelope glyco- elling complex precursor protein gp160 ATPase chain Iswi

7852 Target 5470 DB03965 7860 Target 4856 DB02944 7868 Target 4787 DB02687

TRFE ANAPL Fucose CD209 HUMAN Alpha-D-Mann ENV SIVMK Beta-D-Manno ose.. se..

Ovotransferrin CD209 antigen Envelope glycoprotein gp160

7853 Target 3355 DB03485 7861 Target 4791 DB02717 7869 Target 129 DB00581

TRFE CHICK Alpha-D-Fuco Q59325 CLOTM Cellotetraos BGA2 ECOLI Lactulose se.. e..

Approved Ovotransferrin Cellulose Evolved beta- precursor 1,4-beta- galactosidase cellobiosidase subunit alpha

7854 Target 2595 DB02719 7862 Target 4715 DB04465 7870 Target 2575 DB01818

PYGM RABIT C-(1-Hydrogy XYNA STRLI Lactose MRC1 MOUSE O3-Sulfonylg l-Beta.. alacto..

Glycogen phos- Endo-1,4-beta- Macrophage phorylase, muscle xylanase A mannose receptor form 1 precursor

7855 Target 2595 DB02379 7863 Target 4882 DB02944 7871 Target 4890 DB02944

PYGM RABIT Beta-D-Gluco DPP6 HUMAN Alpha-D-Mann HEMA IAAIC Alpha-D-Mann se.. ose.. ose..

Glycogen phos- Dipeptidyl Hemagglutinin phorylase, muscle aminopeptidase- form like protein 6 Drug-target pairs: R8 16

7872 Target 2505 DB03122 7880 Target 3814 DB03965 7888 Target 2575 DB03965

NOS2 MOUSE B-Octylgluco C1R HUMAN Fucose MRC1 MOUSE Fucose side..

Nitric oxide syn- Complement C1r Macrophage thase, inducible subcomponent mannose receptor 1 precursor

7873 Target 2860 DB03122 7881 Target 4856 DB03965 7889 Target 2860 DB04473

POLG DEN2T B-Octylgluco CD209 HUMAN Fucose POLG DEN2T Alpha-L-Fuco side.. se..

Genome polypro- CD209 antigen Genome polyprotein [Contains: tein [Contains: Major envelope Major envelope protein E; Non- protein E; Non- structural protein structural protein 1 1

7874 Target 2860 DB02687 7882 Target 1756 DB03965 7890 Target 4783 DB04473

POLG DEN2T Beta-D-Manno LYAM2 HUMAN Fucose POLG DEN3P Alpha-L-Fuco se.. se..

Genome polypro- E-selectin precur- Genome polyprotein [Contains: sor tein Major envelope protein E; Non- structural protein 1

7875 Target 4783 DB02687 7883 Target 3923 DB03965 7891 Target 958 DB03965

POLG DEN3P Beta-D-Manno CHLE HUMAN Fucose IGF1R HUMAN Fucose se..

Genome polypro- Cholinesterase Insulin-like tein growth factor 1 receptor precursor

7876 Target 4783 DB02944 7884 Target 2058 DB03965 7892 Target 2782 DB03965

POLG DEN3P Alpha-D-Mann LYAM3 HUMAN Fucose C1S HUMAN Fucose ose..

Genome polypro- P-selectin precur- Complement C1s tein sor subcomponent precursor

7877 Target 958 DB02944 7885 Target 3869 DB03965 7893 Target 1439 DB03965

IGF1R HUMAN Alpha-D-Mann TSP1 HUMAN Fucose TRFL HUMAN Fucose ose..

Insulin-like Thrombospondin- Lactotransferrin growth factor 1 1 precursor receptor precursor

7878 Target 158 DB00273 7886 Target 3609 DB04508 7894 Target 4892 DB03965

SCN1A HUMAN Topiramate HN NDVB Methyl(6s)-1 POLS SFV Fucose -Thio-..

Approved Sodium channel Hemagglutinin- Structural protein type 1 neuraminidase polyprotein subunit alpha

7879 Target 3814 DB02944 7887 Target 952 DB03965 7895 Target 3276 DB03965

C1R HUMAN Alpha-D-Mann DPP4 HUMAN Fucose GRIK2 RAT Fucose ose..

Complement C1r Dipeptidyl pepti- Glutamate recep- subcomponent dase 4 tor, ionotropic kainate 2 precursor Drug-target pairs: R8 17

7896 Target 3837 DB03965 7904 Target 2728 DB02237 7912 Target 4850 DB02944

IL3RB HUMAN Fucose AMT4 PSEST Maltotetraos APOH HUMAN Alpha-D-Mann e.. ose..

Cytokine receptor Glucan 1,4-alpha- Beta-2- common beta maltotetraohydrolase glycoprotein chain precursor 1

7897 Target 4634 DB03965 7905 Target 2728 DB02379 7913 Target 4854 DB02944

MDL1 PRUSE Fucose AMT4 PSEST Beta-D-Gluco TRFL BOVIN Alpha-D-Mann se.. ose..

(R)- Glucan 1,4-alpha- Lactotransferrin mandelonitrile maltotetraohydrolase lyase 1 precursor

7898 Target 1354 DB02944 7906 Target 4634 DB02944 7914 Target 4892 DB02944

BGLR HUMAN Alpha-D-Mann MDL1 PRUSE Alpha-D-Mann POLS SFV Alpha-D-Mann ose.. ose.. ose..

Beta- (R)- Structural glucuronidase mandelonitrile polyprotein precursor lyase 1

7899 Target 4786 DB02944 7907 Target 4857 DB02944 7915 Target 3460 DB02944

LAC1 MELAO Alpha-D-Mann ZA2G HUMAN Alpha-D-Mann MPRI BOVIN Alpha-D-Mann ose.. ose.. ose..

Laccase-1 Zinc-alpha-2- Cation- glycoprotein independent mannose-6- phosphate receptor precursor

7900 Target 4786 DB02687 7908 Target 5481 DB04465 7916 Target 4583 DB02061

LAC1 MELAO Beta-D-Manno Q26964 TRYCR Lactose Q7LIJ0 PHACH Cellobiose se..

Laccase-1 Trans-sialidase Major cellobiohy- drolase

7901 Target 366 DB02687 7909 Target 4742 DB02944 7917 Target 4583 DB04465

ACES DROME Beta-D-Manno Q6ED33 ASPNG Alpha-D-Mann Q7LIJ0 PHACH Lactose se.. ose..

Acetylcholinesterase EstA Major cellobiohy- precursor drolase

7902 Target 366 DB02944 7910 Target 2202 DB03122 7918 Target 3837 DB02944

ACES DROME Alpha-D-Mann STS HUMAN B-Octylgluco IL3RB HUMAN Alpha-D-Mann ose.. side.. ose..

Acetylcholinesterase Steryl-sulfatase Cytokine receptor precursor precursor common beta chain

7903 Target 595 DB02944 7911 Target 1563 DB02944 7919 Target 382 DB00273

FIBA HUMAN Alpha-D-Mann GP1BA HUMAN Alpha-D-Mann GRIK1 HUMAN Topiramate ose.. ose..

Approved Fibrinogen alpha Platelet glycopro- Glutamate recep- chain precur- tein Ib alpha chain tor, ionotropic sor [Contains: precursor kainate 1 Fibrinopeptide A] precursor Drug-target pairs: R8 18

7920 Target 4583 DB02017 7928 Target 2606 DB03995 7936 Target 2763 DB02944

Q7LIJ0 PHACH Imidazole-De NEPU2 THEVU Cyclo-Hepta- CDH PHACH Alpha-D-Mann rived .. Amylos.. ose..

Major cellobiohy- Neopullulanase 2 Cellobiose de- drolase hydrogenase precursor

7921 Target 4671 DB02379 7929 Target 2606 DB02379 7937 Target 4274 DB02944

GUNC CELFI Beta-D-Gluco NEPU2 THEVU Beta-D-Gluco GUX6 HUMIN Alpha-D-Mann se.. se.. ose..

Endoglucanase C Neopullulanase 2 Exoglucanase-6A

7922 Target 4721 DB02944 7930 Target 2606 DB02237 7938 Target 4274 DB02379

P77847 CALSA Alpha-D-Mann NEPU2 THEVU Maltotetraos GUX6 HUMIN Beta-D-Gluco ose.. e.. se..

Beta-1,4- Neopullulanase 2 Exoglucanase-6A mannanase

7923 Target 5562 DB02379 7931 Target 3389 DB03323 7939 Target 4274 DB01697

HXK SCHMA Beta-D-Gluco AMYB SOYBN Maltose GUX6 HUMIN Cellotriose se..

Hexokinase Beta-amylase Exoglucanase-6A

7924 Target 4286 DB01687 7932 Target 3389 DB03281 7940 Target 4274 DB01642

Q99036 TRIRE Mannobiose AMYB SOYBN 2’-Deoxymalt GUX6 HUMIN O1-Methyl-Gl ose.. ucose..

Beta-mannase Beta-amylase Exoglucanase-6A

7925 Target 3365 DB02379 7933 Target 3389 DB02379 7941 Target 4274 DB02717

AMYB BACCE Beta-D-Gluco AMYB SOYBN Beta-D-Gluco GUX6 HUMIN Cellotetraos se.. se.. e..

Beta-amylase pre- Beta-amylase Exoglucanase-6A cursor

7926 Target 3365 DB02645 7934 Target 4668 DB02379 7942 Target 4886 DB02944

AMYB BACCE 3,4-Epoxybut Q9WXN1 THEMA Beta-D-Gluco RHA1 ASPAC Alpha-D-Mann yl-Alp.. se.. ose..

Beta-amylase pre- Laminarinase Rhamnogalacturonan cursor acetylesterase

7927 Target 3365 DB03323 7935 Target 2485 DB03156 7943 Target 4867 DB02944

AMYB BACCE Maltose HYSA STRPN D-Glucuronic Q61353 MOUSE Alpha-D-Mann Acid.. ose..

Beta-amylase pre- Hyaluronate lyase Biliary glycopro- cursor precursor tein Drug-target pairs: R8 19

7944 Target 4558 DB03377 7952 Target 1881 DB02379 7960 Target 4335 DB03296

Q9F5I8 9ALTE D-Galactose- HXK1 HUMAN Beta-D-Gluco Q26966 TRYCR Lactose Sial 4-Sulf.. se.. ic Aci..

Iota-carrageenase, Hexokinase-1 Trans-sialidase CgiA

7945 Target 4558 DB01981 7953 Target 2581 DB02944 7961 Target 2763 DB04096

Q9F5I8 9ALTE 3,6-Anhydro- CSLA PEDHE Alpha-D-Mann CDH PHACH 5-Amino-5-De D-Gala.. ose.. oxy-Ce..

Iota-carrageenase, Chondroitinase Cellobiose de- CgiA AC precursor hydrogenase precursor

7946 Target 2430 DB03863 7954 Target 2581 DB02945 7962 Target 4513 DB01922

CSLB PEDHE 2-O-Methyl F CSLA PEDHE L-Iduronic A AMYP HUMAN Maltosyl-Alp ucose.. cid.. ha (1,..

Chondroitinase B Chondroitinase Pancreatic alpha- precursor AC precursor amylase

7947 Target 2430 DB04515 7955 Target 2581 DB03156 7963 Target 4863 DB02944

CSLB PEDHE 6-Deoxy-2-O- CSLA PEDHE D-Glucuronic EXG1 YEAST Alpha-D-Mann Methyl.. Acid.. ose..

Chondroitinase B Chondroitinase Glucan 1,3- precursor AC precursor beta-glucosidase I/II

7948 Target 2430 DB01869 7956 Target 2430 DB02944 7964 Target 2483 DB03323

CSLB PEDHE Rhamnose CSLB PEDHE Alpha-D-Mann AMYP PIG Maltose ose..

Chondroitinase B Chondroitinase B Pancreatic alpha- precursor precursor amylase precursor

7949 Target 2581 DB01869 7957 Target 2430 DB02379 7965 Target 2483 DB02379

CSLA PEDHE Rhamnose CSLB PEDHE Beta-D-Gluco AMYP PIG Beta-D-Gluco se.. se..

Chondroitinase Chondroitinase B Pancreatic alpha- AC precursor precursor amylase precursor

7950 Target 2581 DB03879 7958 Target 852 DB02944 7966 Target 2483 DB02944

CSLA PEDHE Alpha-L-Meth HEP2 HUMAN Alpha-D-Mann AMYP PIG Alpha-D-Mann yl-Fuc.. ose.. ose..

Chondroitinase Heparin cofactor 2 Pancreatic alpha- AC precursor precursor amylase precursor

7951 Target 2581 DB03863 7959 Target 852 DB00407 7967 Target 2483 DB03277

CSLA PEDHE 2-O-Methyl F HEP2 HUMAN Ardeparin AMYP PIG Amylotriose ucose..

Approved Chondroitinase Heparin cofactor 2 Pancreatic alpha- AC precursor precursor amylase precursor Drug-target pairs: R8 20

7968 Target 4513 DB02379 7976 Target 2582 DB02379 7984 Target 2519 DB03194

AMYP HUMAN Beta-D-Gluco GAOA GIBZE Beta-D-Gluco MBL2 RAT Beta-L-Methy se.. se.. l-Fuco..

Pancreatic alpha- Galactose oxidase Mannose-binding amylase precursor protein C precursor

7969 Target 4513 DB03773 7977 Target 4665 DB02379 7985 Target 2519 DB01979

AMYP HUMAN 6-Deoxy-Alph DEXT PENMI Beta-D-Gluco MBL2 RAT O1-Methyl-Ma a-D-Gl.. se.. nnose..

Pancreatic alpha- Dextranase Mannose-binding amylase protein C precursor

7970 Target 3532 DB02379 7978 Target 2592 DB04116 7986 Target 2519 DB02944

LECG CROAT Beta-D-Gluco BGAL ECOLI Allolactose MBL2 RAT Alpha-D-Mann se.. ose..

Galactose-specific Beta- Mannose-binding lectin galactosidase protein C precursor

7971 Target 3030 DB02379 7979 Target 2592 DB04155 7987 Target 4885 DB02944

AMYS HUMAN Beta-D-Gluco BGAL ECOLI 2-Fluoro-2-D VSM2 TRYBB Alpha-D-Mann se.. eoxy-B.. ose..

Salivary alpha- Beta- Variant surface amylase precursor galactosidase glycoprotein MITAT 1.2

7972 Target 5559 DB02379 7980 Target 2592 DB04465 7988 Target 2723 DB02802

NEPU BACST Beta-D-Gluco BGAL ECOLI Lactose CHTB VIBCH 5-Aminocarbo se.. nyl-3-..

Neopullulanase Beta- Cholera entero- galactosidase toxin subunit B precursor

7973 Target 2570 DB02379 7981 Target 2592 DB02632 7989 Target 2723 DB02213

TETX CLOTE Beta-D-Gluco BGAL ECOLI 1-O-[P-Nitro CHTB VIBCH Metanitrophe se.. phenyl.. nyl-Al..

Tetanus toxin pre- Beta- Cholera entero- cursor galactosidase toxin subunit B precursor

7974 Target 2570 DB04465 7982 Target 2592 DB01920 7990 Target 4842 DB02944

TETX CLOTE Lactose BGAL ECOLI 1-O-[O-Nitro PLMP GRIFR Alpha-D-Mann phenyl.. ose..

Tetanus toxin pre- Beta- Peptidyl-Lys met- cursor galactosidase alloendopeptidase

7975 Target 2437 DB02944 7983 Target 2519 DB03879 7991 Target 2723 DB02379

NOS1 RAT Alpha-D-Mann MBL2 RAT Alpha-L-Meth CHTB VIBCH Beta-D-Gluco ose.. yl-Fuc.. se..

Nitric-oxide Mannose-binding Cholera entero- synthase, brain protein C toxin subunit B precursor precursor Drug-target pairs: R8 21

7992 Target 2583 DB02944 8000 Target 3091 DB03323 8008 Target 4656 DB03965

LEC ERYCO Alpha-D-Mann PHSM ECOLI Maltose MYRA SINAL Fucose ose..

Lectin precursor Maltodextrin Myrosinase MA1 phosphorylase

7993 Target 2583 DB02687 8001 Target 3091 DB02379 8009 Target 2583 DB03965

LEC ERYCO Beta-D-Manno PHSM ECOLI Beta-D-Gluco LEC ERYCO Fucose se.. se..

Lectin precursor Maltodextrin Lectin precursor phosphorylase

7994 Target 2583 DB02379 8002 Target 3073 DB03122 8010 Target 2583 DB03283

LEC ERYCO Beta-D-Gluco LIPG CANFA B-Octylgluco LEC ERYCO beta-L-fucos se.. side.. e..

Lectin precursor Gastric triacyl- Lectin precursor glycerol lipase precursor

7995 Target 2583 DB04465 8003 Target 2829 DB02944 8011 Target 2374 DB03879

LEC ERYCO Lactose KRE2 YEAST Alpha-D-Mann LEC1 ULEEU Alpha-L-Meth ose.. yl-Fuc..

Lectin precursor Glycolipid Anti-H(O) lectin 1 2-alpha- mannosyltransferase

7996 Target 5566 DB02379 8004 Target 2829 DB02284 8012 Target 2374 DB03965

AMYG ASPNG Beta-D-Gluco KRE2 YEAST 1-O-Methyl-A LEC1 ULEEU Fucose se.. lpha-D..

Glucoamylase Glycolipid Anti-H(O) lectin 1 2-alpha- mannosyltransferase

7997 Target 3322 DB02944 8005 Target 4841 DB02379 8013 Target 4666 DB03965

AMYG ASPSH Alpha-D-Mann Q9Y780 COPCI Beta-D-Gluco Q9HYN5 PSEAE Fucose ose.. se..

Glucoamylase pre- Laccase 1 Fucose-binding cursor lectin PA-IIL

7998 Target 3322 DB02379 8006 Target 4841 DB02944 8014 Target 5475 DB03965

AMYG ASPSH Beta-D-Gluco Q9Y780 COPCI Alpha-D-Mann CGL2 COPCI Fucose se.. ose..

Glucoamylase pre- Laccase 1 Galectin-2 cursor

7999 Target 5569 DB02379 8007 Target 5557 DB02379 8015 Target 5478 DB03965

P94622 CLOCL Beta-D-Gluco MALE PYRFU Beta-D-Gluco AR5A PHAVU Fucose se.. se..

Endo-1,4-beta Maltotriose- Arcelin-5A glucanase EngF binding protein Drug-target pairs: R8 22

8016 Target 2212 DB03965 8024 Target 2293 DB02379 8032 Target 2252 DB01633

SUMF2 HUMAN Fucose CDGT1 BACCI Beta-D-Gluco GUN5 BACAG Deoxy-2-Fluo se.. ro-B-D..

Sulfatase- Cyclomaltodextrin Endoglucanase 5A modifying factor glucanotrans- 2 precursor ferase precursor

8017 Target 3169 DB03773 8025 Target 4667 DB02379 8033 Target 2252 DB02379

AMY BACAM 6-Deoxy-Alph Q9KG76 BACHD Beta-D-Gluco GUN5 BACAG Beta-D-Gluco a-D-Gl.. se.. se..

Alpha-amylase BH0236 protein Endoglucanase 5A precursor

8018 Target 3207 DB04319 8026 Target 5637 DB04386 8034 Target 2541 DB02379

CDGT THETU 6-Deoxygluco Q9AQS0 BACGL 4,6-O-(1-Car NEPU1 THEVU Beta-D-Gluco se.. boxyet.. se..

Cyclomaltodextrin Xanthan lyase Neopullulanase 1 glucanotrans- precursor ferase precursor

8019 Target 2523 DB04319 8027 Target 5637 DB04596 8035 Target 4107 DB00638

CDGT2 BACCI 6-Deoxygluco Q9AQS0 BACGL 4,6-O-(1-CAR Q9F0I5 PAEMA Inulin se.. BOXYET..

Approved Cyclomaltodextrin Xanthan lyase Cycloinulo- glucanotrans- oligosaccharide ferase precursor fructanotrans- ferase

8020 Target 5476 DB03965 8028 Target 5637 DB04597 8036 Target 2293 DB01719

CPGP2 ZINOF Fucose Q9AQS0 BACGL [4,6-O-(1-CA CDGT1 BACCI Thio-Maltope RBOXYE.. ntaose..

Cysteine pro- Xanthan lyase Cyclomaltodextrin teinase GP-II glucanotransferase precursor

8021 Target 2252 DB02017 8029 Target 4740 DB02944 8037 Target 2293 DB03198

GUN5 BACAG Imidazole-De Q700S9 PENSQ Alpha-D-Mann CDGT1 BACCI Thio-Maltohe rived .. ose.. xaose..

Endoglucanase 5A Beta- Cyclomaltodextrin galactosidase glucanotransferase precursor

8022 Target 2252 DB04086 8030 Target 2252 DB02061 8038 Target 3153 DB02379

GUN5 BACAG 2’,4’-Dinitr GUN5 BACAG Cellobiose DHGB ACICA Beta-D-Gluco opheny.. se..

Endoglucanase 5A Endoglucanase 5A Quinoprotein glucose dehydrogenase-B precursor

8023 Target 2948 DB02379 8031 Target 2252 DB01642 8039 Target 4651 DB02743

AMY PSEHA Beta-D-Gluco GUN5 BACAG O1-Methyl-Gl Q65CX5 BACLD Beta-1,4-Gal se.. ucose.. actobi..

Alpha-amylase Endoglucanase 5A YvfO precursor Drug-target pairs: R8 23

8040 Target 4651 DB04248 8048 Target 4559 DB03652 8056 Target 2552 DB04465

Q65CX5 BACLD Beta-1,4-Gal Q9KWT6 9SPHN L-Glucuronic LECG ARAHY Lactose actotr.. Acid..

YvfO AlgQ1 Galactose-binding lectin precursor

8041 Target 5042 DB03122 8049 Target 3169 DB02379 8057 Target 2552 DB04046

Q9KS51 VIBCH B-Octylgluco AMY BACAM Beta-D-Gluco LECG ARAHY Methyl-Beta- side.. se.. Galact..

Multidrug resis- Alpha-amylase Galactose-binding tance protein, precursor lectin precursor putative

8042 Target 2508 DB02379 8050 Target 3029 DB03122 8058 Target 2552 DB02379

CDGT BACS0 Beta-D-Gluco OMPT ECOLI B-Octylgluco LECG ARAHY Beta-D-Gluco se.. side.. se..

Cyclomaltodextrin Protease 7 precur- Galactose-binding glucanotrans- sor lectin precursor ferase precursor

8043 Target 3207 DB02379 8051 Target 3403 DB03190 8059 Target 4871 DB02944

CDGT THETU Beta-D-Gluco PBPX STRR6 N-Octanoyl-B EBA3 FLAME Alpha-D-Mann se.. -D-Fru.. ose..

Cyclomaltodextrin Penicillin-binding Endo-beta-N- glucanotrans- protein 2X acetylglucosaminidase ferase precursor F3

8044 Target 2523 DB01909 8052 Target 3499 DB04465 8060 Target 2802 DB02061

CDGT2 BACCI Alpha-Cyclod GGTA1 BOVIN Lactose GUNG CLOCE Cellobiose extrin..

Cyclomaltodextrin N- Endoglucanase G glucanotrans- acetyllactosaminide precursor ferase precursor alpha-1,3- galactosyltransferase

8045 Target 2523 DB02379 8053 Target 3499 DB02379 8061 Target 2802 DB02379

CDGT2 BACCI Beta-D-Gluco GGTA1 BOVIN Beta-D-Gluco GUNG CLOCE Beta-D-Gluco se.. se.. se..

Cyclomaltodextrin N- Endoglucanase G glucanotrans- acetyllactosaminide precursor ferase precursor alpha-1,3- galactosyltransferase

8046 Target 2523 DB03323 8054 Target 4670 DB02379 8062 Target 5556 DB02379

CDGT2 BACCI Maltose O07653 9GAMM Beta-D-Gluco O08452 PYRFU Beta-D-Gluco se.. se..

Cyclomaltodextrin Cellulase B Alpha amylase glucanotransferase precursor

8047 Target 4559 DB01982 8055 Target 2660 DB02379 8063 Target 2531 DB02379

Q9KWT6 9SPHN D-Mannuronic BGLC MAIZE Beta-D-Gluco AMY BACSU Beta-D-Gluco Acid.. se.. se..

AlgQ1 Beta-glucosidase, Alpha-amylase chloroplast precursor precursor Drug-target pairs: R8 24

8064 Target 2645 DB02061 8072 Target 5561 DB02379 8080 Target 1072 DB02944

GUN BACS6 Cellobiose LAMB SALTY Beta-D-Gluco GRAB HUMAN Alpha-D-Mann se.. ose..

Endoglucanase Maltoporin Granzyme B pre- precursor cursor

8065 Target 4784 DB02687 8073 Target 2564 DB02379 8081 Target 3793 DB02379

Q9RIK9 THEMA Beta-D-Manno AMT6 BACS7 Beta-D-Gluco ASPA ECOLI Beta-D-Gluco se.. se.. se..

Beta-mannosidase Glucan 1,4-alpha- Aspartate maltohexaosidase ammonia-lyase precursor

8066 Target 4622 DB02379 8074 Target 3747 DB02379 8082 Target 3009 DB02379

O82839 BACSP Beta-D-Gluco Q54331 STRLI Beta-D-Gluco GUB PAEMA Beta-D-Gluco se.. se.. se..

Amylase Cellulase B pre- Beta-glucanase cursor precursor

8067 Target 3258 DB02944 8075 Target 5558 DB02379 8083 Target 4869 DB02944

MAN12 PENCI Alpha-D-Mann AMYB HORVU Beta-D-Gluco COAT PBCV1 Alpha-D-Mann ose.. se.. ose..

Mannosyl- Beta-amylase Major capsid pro- oligosaccharide tein alpha-1,2- mannosidase precursor

8068 Target 2427 DB04526 8076 Target 4866 DB02944 8084 Target 2826 DB02379

FHUA ECOLI L-Glycero-D- GOX PENAG Alpha-D-Mann GFO ZYMMO Beta-D-Gluco Manno-.. ose.. se..

Ferrichrome-iron Glucose oxidase Glucose–fructose receptor precursor oxidoreductase precursor

8069 Target 2427 DB02379 8077 Target 4656 DB02944 8085 Target 4817 DB02772

FHUA ECOLI Beta-D-Gluco MYRA SINAL Alpha-D-Mann SCRY SALTY Sucrose se.. ose..

Ferrichrome-iron Myrosinase MA1 Sucrose porin receptor precursor

8070 Target 5498 DB02379 8078 Target 4669 DB02379 8086 Target 2743 DB02346

LAMB ECOLI Beta-D-Gluco XYNA1 CLOSR Beta-D-Gluco CSD SYNY3 3’-O-N-Octan se.. se.. oyl-a-..

Maltoporin Endo-1,4-beta- Probable cysteine xylanase A desulfurase

8071 Target 5560 DB02379 8079 Target 4877 DB02944 8087 Target 4748 DB02772

XYNA THEMA Beta-D-Gluco Q9ZF13 THEFU Alpha-D-Mann SACB BACSU Sucrose se.. ose..

Endo-1,4-beta- Beta-mannanase Levansucrase xylanase A Drug-target pairs: R8 25

8088 Target 5348 DB03511 8096 Target 5475 DB02379 8104 Target 3026 DB02687

P79074 9AGAR Galacturonic CGL2 COPCI Beta-D-Gluco NRAM IATRA Beta-D-Manno Acid.. se.. se..

Endopolygalacturonase Galectin-2 Neuraminidase

8089 Target 3568 DB04465 8097 Target 2560 DB02632 8105 Target 3026 DB02944

LEC ERYCG Lactose THGA ECOLI 1-O-[P-Nitro NRAM IATRA Alpha-D-Mann phenyl.. ose..

Lectin Galactoside O- Neuraminidase acetyltransferase

8090 Target 2978 DB03323 8098 Target 3340 DB03122 8106 Target 4846 DB02944

AMYM BACST Maltose LIPB CANAR B-Octylgluco Q96TU3 ASPAW Alpha-D-Mann side.. ose..

Maltogenic alpha- Lipase B precur- Exo-inulinase amylase precursor sor

8091 Target 2374 DB02944 8099 Target 4509 DB02379 8107 Target 5570 DB02379

LEC1 ULEEU Alpha-D-Mann BUDC KLEPN Beta-D-Gluco GUN4 THEFU Beta-D-Gluco ose.. se.. se..

Anti-H(O) lectin 1 Acetoin(diacetyl) Endoglucanase E- reductase 4

8092 Target 3547 DB04465 8100 Target 4852 DB02944 8108 Target 3236 DB02061

ETXB STAAU Lactose RTN4R HUMAN Alpha-D-Mann GUNC FUSOX Cellobiose ose..

Enterotoxin type Reticulon-4 recep- Endoglucanase B precursor tor type C precursor

8093 Target 3547 DB02379 8101 Target 4874 DB02944 8109 Target 2701 DB02772

ETXB STAAU Beta-D-Gluco PPAP RAT Alpha-D-Mann NOSO STAAW Sucrose se.. ose..

Enterotoxin type Prostatic acid Nitric oxide syn- B precursor phosphatase thase oxygenase

8094 Target 4666 DB02379 8102 Target 4663 DB02379 8110 Target 4843 DB02944

Q9HYN5 PSEAE Beta-D-Gluco Q9C171 PIREQ Beta-D-Gluco EFNB2 MOUSE Alpha-D-Mann se.. se.. ose..

Fucose-binding Non-catalytic pro- Ephrin-B2 lectin PA-IIL tein 1

8095 Target 4666 DB02944 8103 Target 4663 DB02687 8111 Target 5567 DB02379

Q9HYN5 PSEAE Alpha-D-Mann Q9C171 PIREQ Beta-D-Manno AGI2 WHEAT Beta-D-Gluco ose.. se.. se..

Fucose-binding Non-catalytic pro- Agglutinin lectin PA-IIL tein 1 isolectin 2 Drug-target pairs: R8 26

8112 Target 5027 DB02379 8120 Target 2415 DB02944 8128 Target 4792 DB02722

AGI3 WHEAT Beta-D-Gluco OPSD BOVIN Alpha-D-Mann Q8VVD2 BACST 4-O-Methyl-B se.. ose.. eta-D-..

Agglutinin Rhodopsin Alpha- isolectin 3 glucuronidase

8113 Target 5564 DB02379 8121 Target 2415 DB02687 8129 Target 4792 DB03156

AGI1 WHEAT Beta-D-Gluco OPSD BOVIN Beta-D-Manno Q8VVD2 BACST D-Glucuronic se.. se.. Acid..

Agglutinin Rhodopsin Alpha- isolectin 1 glucuronidase

8114 Target 5471 DB03965 8122 Target 5416 DB02379 8130 Target 4792 DB04303

FUCL ANGAN Fucose COA1 POVMP Beta-D-Gluco Q8VVD2 BACST 4-O-Methyl-A se.. lpha-D..

Fucolectin Coat protein VP1 Alpha- glucuronidase

8115 Target 4893 DB02944 8123 Target 5486 DB04046 8131 Target 18 DB02944

RNS3 PYRPY Alpha-D-Mann Q8W1R6 GRISI Methyl-Beta- FCERA HUMAN Alpha-D-Mann ose.. Galact.. ose..

Ribonuclease S-3 GSI-B4 isolectin High affinity immunoglobulin epsilon receptor alpha-subunit precursor

8116 Target 3202 DB02772 8124 Target 4664 DB02379 8132 Target 18 DB03965

ACTS RAT Sucrose Q8NJY3 9ASCO Beta-D-Gluco FCERA HUMAN Fucose se..

Actin, alpha skele- Endoglucanase High affinity tal muscle immunoglobulin epsilon receptor alpha-subunit precursor

8117 Target 4660 DB02379 8125 Target 4860 DB02944 8133 Target 3066 DB02687

GUN1 HUMIN Beta-D-Gluco MA1A1 MOUSE Alpha-D-Mann CAH14 MOUSE Beta-D-Manno se.. ose.. se..

Endoglucanase 1 Mannosyl- Carbonic an- oligosaccharide hydrase 14 1,2-alpha- precursor mannosidase IA

8118 Target 5473 DB03965 8126 Target 3286 DB02944 8134 Target 4864 DB02944

VSP2 AGKAC Fucose CBPD LOPSP Alpha-D-Mann RHGA ASPAC Alpha-D-Mann ose.. ose..

Venom serine pro- Carboxypeptidase Rhamnogalacturonase teinase Dav-PA D A

8119 Target 2415 DB02451 8127 Target 4692 DB02379 8135 Target 4702 DB04303

OPSD BOVIN B-Nonylgluco MUTY ECOLI Beta-D-Gluco Q8VP74 9GAMM 4-O-Methyl-A side.. se.. lpha-D..

Rhodopsin A/G-specific ade- Alpha- nine glycosylase glucuronidase Drug-target pairs: R8 27

8136 Target 3480 DB02687 8144 Target 4785 DB02944 8152 Target 5752 DB04735

MANA PSEFL Beta-D-Manno IGHG1 HUMAN Alpha-D-Mann PSBA1 SYNEL MONOGALACTOS se.. ose.. YL-DIA..

Mannan endo-1,4- Ig gamma-1 chain Photosystem Q(B) beta-mannosidase C region protein precursor

8137 Target 3480 DB02944 8145 Target 4785 DB02687 8153 Target 4879 DB02944

MANA PSEFL Alpha-D-Mann IGHG1 HUMAN Beta-D-Manno CARP RHIMI Alpha-D-Mann ose.. se.. ose..

Mannan endo-1,4- Ig gamma-1 chain Mucorpepsin beta-mannosidase C region precursor

8138 Target 3367 DB02772 8146 Target 3206 DB02944 8154 Target 2440 DB02379

ALGD PSEAE Sucrose ALLN1 ALLSA Alpha-D-Mann GUNF CLOCE Beta-D-Gluco ose.. se..

GDP-mannose 6- Alliin lyase 1 pre- Endoglucanase F dehydrogenase cursor precursor

8139 Target 592 DB00273 8147 Target 3206 DB03485 8155 Target 2440 DB01642

CAH4 HUMAN Topiramate ALLN1 ALLSA Alpha-D-Fuco GUNF CLOCE O1-Methyl-Gl se.. ucose..

Approved Carbonic anhy- Alliin lyase 1 pre- Endoglucanase F drase 4 precursor cursor precursor

8140 Target 872 DB00273 8148 Target 2372 DB01869 8156 Target 5209 DB03277

GBRA1 HUMAN Topiramate TSPE BPP22 Rhamnose Q9RHZ6 ALIAC Amylotriose

Approved Gamma- Bifunctional tail Maltose binding aminobutyric-acid protein protein receptor subunit alpha-1 precursor

8141 Target 3327 DB02379 8149 Target 2372 DB02379 8157 Target 5209 DB03323

ISWI DROME Beta-D-Gluco TSPE BPP22 Beta-D-Gluco Q9RHZ6 ALIAC Maltose se.. se..

Chromatin remod- Bifunctional tail Maltose binding elling complex protein protein ATPase chain Iswi

8142 Target 4785 DB04473 8150 Target 2372 DB02944 8158 Target 2767 DB02944

IGHG1 HUMAN Alpha-L-Fuco TSPE BPP22 Alpha-D-Mann RIP1 MOMCH Alpha-D-Mann se.. ose.. ose..

Ig gamma-1 chain Bifunctional tail Ribosome- C region protein inactivating protein momordin I precursor

8143 Target 4785 DB03965 8151 Target 2661 DB03426 8159 Target 5417 DB02379

IGHG1 HUMAN Fucose PCP1 AMPCA Digalactosyl P93248 9FABA Beta-D-Gluco Diacy.. se..

Ig gamma-1 chain Peridinin- Lectin C region chlorophyll a-binding protein 1, chloroplast precursor Drug-target pairs: R8 28

8160 Target 4273 DB02944 8168 Target 3373 DB02944 8176 Target 127 DB02451

Q8GSD2 9FABA Alpha-D-Mann PER COPCI Alpha-D-Mann CB2A SPIOL B-Nonylgluco ose.. ose.. side..

Lectin Peroxidase precur- Chlorophyll a-b sor binding protein, chloroplast precursor

8161 Target 4273 DB01642 8169 Target 2585 DB02944 8177 Target 5043 DB03122

Q8GSD2 9FABA O1-Methyl-Gl PER ARTRA Alpha-D-Mann O50426 MYCTU B-Octylgluco ucose.. ose.. side..

Lectin Peroxidase precur- N-Acetyl-1-D- sor myo-Inosityl- 2-Amino-2- Deoxy-alpha-D- Glucopyranoside Deacetylase mshB

8162 Target 4273 DB01979 8170 Target 3373 DB02687 8178 Target 5555 DB02379

Q8GSD2 9FABA O1-Methyl-Ma PER COPCI Beta-D-Manno LEG1 CONMY Beta-D-Gluco nnose.. se.. se..

Lectin Peroxidase precur- Congerin-1 sor

8163 Target 4273 DB02284 8171 Target 3546 DB04465 8179 Target 2856 DB02379

Q8GSD2 9FABA 1-O-Methyl-A NANH MICVI Lactose GNPI HUMAN Beta-D-Gluco lpha-D.. se..

Lectin Sialidase precur- Glucosamine- sor 6-phosphate isomerase

8164 Target 4557 DB01979 8172 Target 4560 DB01982 8180 Target 2814 DB02944

LEC1 CRAMO O1-Methyl-Ma Q9KWT5 9SPHN D-Mannuronic CARP YEAST Alpha-D-Mann nnose.. Acid.. ose..

Mannose/glucose- AlgQ2 Saccharopepsin specific lectin precursor Cramoll

8165 Target 5553 DB02379 8173 Target 4560 DB03652 8181 Target 4826 DB03485

GUN1 ACIC1 Beta-D-Gluco Q9KWT5 9SPHN L-Glucuronic Q9XEI3 HORVD Alpha-D-Fuco se.. Acid.. se..

Endoglucanase E1 AlgQ2 Beta-D-glucan ex- ohydrolase isoen- zyme ExoI

8166 Target 357 DB00273 8174 Target 4868 DB02944 8182 Target 4826 DB03965

CAH2 HUMAN Topiramate GOX ASPNG Alpha-D-Mann Q9XEI3 HORVD Fucose ose..

Approved Carbonic anhy- Glucose oxidase Beta-D-glucan ex- drase 2 ohydrolase isoen- zyme ExoI

8167 Target 357 DB02894 8175 Target 127 DB03426 8183 Target 4826 DB02944

CAH2 HUMAN Sulfamic Aci CB2A SPIOL Digalactosyl Q9XEI3 HORVD Alpha-D-Mann d 2,3-.. Diacy.. ose..

Carbonic anhy- Chlorophyll a-b Beta-D-glucan ex- drase 2 binding protein, ohydrolase isoen- chloroplast zyme ExoI precursor Drug-target pairs: R8 29

8184 Target 4826 DB03990 8192 Target 2427 DB02700 8200 Target 5246 DB03389

Q9XEI3 HORVD 4’-Nitrophen FHUA ECOLI 3-Deoxy-D-Gl Q9KB30 BACHD Xylopyranose yl-3i-.. ucosam..

Beta-D-glucan ex- Ferrichrome-iron Xylanase Y ohydrolase isoen- receptor precursor zyme ExoI

8185 Target 4826 DB03263 8193 Target 5245 DB03389 8201 Target 5016 DB03389

Q9XEI3 HORVD Thiocellobio Q59675 9GAMM Xylopyranose XYNA THEAU Xylopyranose se..

Beta-D-glucan ex- Endo-beta-1,4- Endo-1,4-beta- ohydrolase isoen- xylanase xylanase zyme ExoI

8186 Target 4666 DB02561 8194 Target 2430 DB03389 8202 Target 3711 DB03142

Q9HYN5 PSEAE Beta-D-Fruct CSLB PEDHE Xylopyranose ARAC ECOLI Alpha-L-Arab opyran.. inose..

Fucose-binding Chondroitinase B Arabinose operon lectin PA-IIL precursor regulatory protein

8187 Target 4273 DB02561 8195 Target 2581 DB03389 8203 Target 4661 DB03389

Q8GSD2 9FABA Beta-D-Fruct CSLA PEDHE Xylopyranose Q8GZD5 9ROSI Xylopyranose opyran..

Lectin Chondroitinase Xyloglucan endo- AC precursor transglycosylase

8188 Target 1525 DB00686 8196 Target 3365 DB03389 8204 Target 5248 DB03389

FGF2 HUMAN Pentosan Pol AMYB BACCE Xylopyranose XYNA BACCI Xylopyranose ysulfa..

Approved Heparin-binding Beta-amylase pre- Endo-1,4-beta- growth factor 2 cursor xylanase precursor

8189 Target 361 DB00686 8197 Target 3500 DB03586 8205 Target 5247 DB03389

FGF4 HUMAN Pentosan Pol YICI ECOLI 5(R)-5-Fluor XYN1 BACST Xylopyranose ysulfa.. o-Beta..

Approved Fibroblast growth Putative family 31 Endo-1,4-beta- factor 4 precursor glucosidase yicI xylanase

8190 Target 2372 DB02590 8198 Target 4715 DB03389 8206 Target 3057 DB03142

TSPE BPP22 Abequose XYNA STRLI Xylopyranose ARAF ECOLI Alpha-L-Arab inose..

Bifunctional tail Endo-1,4-beta- L-arabinose- protein xylanase A binding periplasmic protein precursor

8191 Target 2372 DB04028 8199 Target 5249 DB03389 8207 Target 3057 DB03246

TSPE BPP22 Tyvelose Q7SI98 STROI Xylopyranose ARAF ECOLI Beta-L-Arabi nose..

Bifunctional tail Hydrolase L-arabinose- protein binding periplasmic protein precursor Drug-target pairs: R8 30

8208 Target 2260 DB03911 8216 Target 5023 DB03389 8224 Target 2534 DB02639

XYLA STRRU L-Xylose (Cy Q7SIE2 BACAG Xylopyranose CONA CANVI 4-Methylumbe clic F.. llifer..

Xylose isomerase Glycoside hydro- Concanavalin A lase

8209 Target 4830 DB03389 8217 Target 4893 DB03389 8225 Target 3171 DB04268

Q9ZB17 9LACT Xylopyranose RNS3 PYRPY Xylopyranose LYSC2 ONCMY Methylumbell iferyl..

Aldose 1- Ribonuclease S-3 Lysozyme C II epimerase precursor

8210 Target 4830 DB03142 8218 Target 2448 DB03389 8226 Target 3171 DB02759

Q9ZB17 9LACT Alpha-L-Arab GUX CELFI Xylopyranose LYSC2 ONCMY 4-Methylumbe inose.. llifer..

Aldose 1- Exoglucanase/xylanase Lysozyme C II epimerase precursor [In- precursor cludes: Exoglu- canase

8211 Target 4808 DB03389 8219 Target 2448 DB03717 8227 Target 4604 DB03721

O68541 9GAMM Xylopyranose GUX CELFI 3-Hydroxy-4- EST1 HUMAN O-Sialic Aci (3,4,5.. d..

Endoxylanase Exoglucanase/xylanase Liver car- precursor [In- boxylesterase cludes: Exoglu- 1 canase

8212 Target 2767 DB03389 8220 Target 2801 DB02314 8228 Target 5415 DB03721

RIP1 MOMCH Xylopyranose MURE ECOLI Uridine-5’-D SN MOUSE O-Sialic Aci iphosp.. d..

Ribosome- UDP-N- Sialoadhesin inactivating acetylmuramoylalanyl- protein momordin D-glutamate–2,6- I precursor diaminopimelate ligase

8213 Target 5250 DB03389 8221 Target 2651 DB02196 8229 Target 244 DB03740

Q8RJN8 PSEHA Xylopyranose MURG ECOLI Uridine-Diph ACE HUMAN 2-(Acetylami osphat.. no)-2-..

Endo-1,4-beta- UDP-N- Angiotensin- xylanase acetylglucosamine– converting N-acetylmuramyl- enzyme, somatic (pentapeptide) isoform precursor pyrophosphoryl- undecaprenol N- acetylglucosamine transferase 8214 Target 4656 DB03389 8222 Target 2306 DB03397 8230 Target 434 DB00141

MYRA SINAL Xylopyranose MURA SHIFL Uridine-Diph ANAG HUMAN N-Acetyl-D-g osphat.. lucosa..

Approved Myrosinase MA1 UDP-N- Alpha-N- acetylglucosamine acetylglucosaminidase 1- precursor carboxyvinyltransferase

8215 Target 4669 DB03389 8223 Target 2367 DB04174 8231 Target 4673 DB02397

XYNA1 CLOSR Xylopyranose MURA ENTCL 3’-1-Carboxy LEC VICVI O-(2-Acetami -1-Pho.. do-2-D..

Endo-1,4-beta- UDP-N- Lectin B4 xylanase A acetylglucosamine 1- carboxyvinyltransferase Drug-target pairs: R8 31

8232 Target 1253 DB01296 8240 Target 3065 DB04426 8248 Target 2916 DB03013

IFNG HUMAN Glucosamine LEC4 GRISI Alpha-Methyl CHB SERMA Di(N-Acetyl- -N-Ace.. D-Gluc..

Approved Interferon gamma Lectin-4 Chitobiase precur- precursor sor

8233 Target 65 DB01296 8241 Target 3372 DB04282 8249 Target 760 DB03959

MMP9 HUMAN Glucosamine BGAL SULSO 2-Deoxy-2flu FGF1 HUMAN N,O6-Disulfo oro-Gl.. -Gluco..

Approved Matrix Beta- Heparin-binding metalloproteinase- galactosidase growth factor 1 9 precursor precursor

8234 Target 4013 DB00141 8242 Target 5753 DB04736 8250 Target 777 DB01296

B4GT2 HUMAN N-Acetyl-D-g PGPLE DROME 2-ACETAMIDO- TNFA HUMAN Glucosamine lucosa.. 2-DEOX..

Approved Approved Beta-1,4- Peptidoglycan- Tumor necrosis galactosyltransferase recognition factor precursor 2 protein-LE

8235 Target 4015 DB00141 8243 Target 2448 DB04282 8251 Target 4327 DB03219

NAGPA HUMAN N-Acetyl-D-g GUX CELFI 2-Deoxy-2flu Q54527 9ACTO 11-Deoxy-Bet lucosa.. oro-Gl.. a-Rhod..

Approved N- Exoglucanase/xylanase RdmB acetylglucosamine- precursor [In- 1-phosphodiester cludes: Exoglu- alpha-N- canase acetylglucosaminidase

8236 Target 3058 DB03013 8244 Target 2654 DB03959 8252 Target 308 DB00955

LYSC MELGA Di(N-Acetyl- VCP VACCV N,O6-Disulfo RS12 ECOLI Netilmicin D-Gluc.. -Gluco..

Approved Lysozyme C pre- Complement con- 30S ribosomal cursor trol protein pre- protein S12 cursor

8237 Target 2384 DB04426 8245 Target 4011 DB00141

MBL1 RAT Alpha-Methyl B4GT3 HUMAN N-Acetyl-D-g -N-Ace.. lucosa..

Approved Mannose-binding Beta-1,4- protein A galactosyltransferase precursor 3

8238 Target 2384 DB03721 8246 Target 1943 DB03959

MBL1 RAT O-Sialic Aci HGF HUMAN N,O6-Disulfo d.. -Gluco..

Mannose-binding Hepatocyte protein A growth factor precursor precursor

8239 Target 3072 DB02657 8247 Target 1373 DB03740

NAGA BACSU Glucosamine GLCM HUMAN 2-(Acetylami 6-Phos.. no)-2-..

N- Glucosylceramidase acetylglucosamine- precursor 6-phosphate deacetylase