2000 Brinker International Awards for Breast Cancer Research
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frontThe Susan G. Komen Breast Cancer Foundation’sline International Newsletter Winter 2001 2000 Brinker International Awards for Breast Cancer Research he Komen Foundation presented the 2000 Brinker T International Awards for Breast Cancer Research at the 23rd Annual San Antonio Breast Cancer Symposium this past December. Established by the Foundation in 1992, the two awards recognize leading scientists for outstanding contributions in the fields of basic and clinical breast cancer research. 2000 2000 The 2000 Basic Research Award was presented to Angela Basic Science Award Clinical Research Award Brodie, Ph.D., Professor in the Department of Pharmacology Angela Brodie, Ph.D. Dimitrios Trichopoulos, M.D. and Experimental Therapeutics at the University of Maryland. Professor, Department of Vincent L. Gregory Professor of The Clinical Research Award was presented to Dimitrios Pharmacology and Cancer Prevention and Trichopoulos, M.D., Vincent L. Gregory Professor of Cancer Experimental Therapeutics, Professor of Epidemiology, Prevention and Professor of Epidemiology at Harvard School of Medicine, Harvard University, University, and Professor of Hygiene and Epidemiology at University of Maryland, Boston, Massachusetts, and the University of Athens in Greece. Baltimore, Maryland Professor of Hygiene and Epidemiology, Each recipient received $10,000 and a crystal statuette from University of Athens, Greece Tiffany & Co. The endowment began from a partnership between the Komen Foundation and Brinker International, the world’s premier multi-operator restaurant company, 2000 Basic Science Award which contributed the proceeds of its Chili’s 10K race and Angela Brodie, Ph.D. chili cook-off. The endowment now assures the continuation and growth of the Brinker Awards. r. Angela Brodie’s work began with basic research on the biochemistry and pharmacology of aromatase, spanned The award ceremony was D preclinical studies through the testing of aromatase inhibitors in inside held during the San Antonio animal models and forged through clinical trials to the approval Breast Cancer Conference, Suzy Komen Award Established 2 of a novel treatment for breast cancer. Dr. Brodie developed a Lee National Denim Day® 3 which was founded in 1978 strong interest in the role of estrogens in breast cancer at the A Celebration of Life 3 as a one-day event involving Christie Hospital in Manchester, UK, site of the Mission Conference 2000 Highlights 5 doctors in a five-state area. FDA Approves Arimidex® 5 first tamoxifen clinical trials. Komen Affiliate News 6 Today the conference is an international event featuring Education Updates 8 In 1972, the Brodie laboratory at the Worcester Foundation for Clinical Trials and Informed Consent 9 world-renowned speakers. Experimental Biology reported the first of a number of compounds Samsung and Sprint PCS 9 The conference has grown to that are potent selective inhibitors of aromatase, the enzyme that LPGA 10 a place of prominence and Ford Continues Support 11 catalyzes the key step in the biosynthesis of estrogens. Pink Tulips for the Cure™ 11 importance for the dissemi- nation of the latest findings Volunteer Voices: Helpline Volunteers 11 Dr. Brodie proposed that selective inhibition of aromatase Ultimate Drive™ 12 in breast cancer research might be of benefit in breast cancer treatment and received a Bowl for the Cure™ 12 and remains dedicated to grant from the National Institutes of Health (NIH) to study Soraya Shines at Miami Race 12 addressing breast cancer 2001 Komen Race for the Cure® 13 this hypothesis in 1975. At that time, all available antiestrogens concerns by providing a Sing for the Cure™ CD 13 were partial estrogen agonists as well as antagonists. In 1977, meaningful forum for the Wacoal America, Parade and Dr. Brodie published data demonstrating the specificity and Ethicon Endo-Surgery 14 pursuit of the elimination efficacy of a potent aromatase inhibitor in an animal model. Ways to Give 15 of the disease. Susan Madeline Komen 16 (continued on page 4) frontline 2 Suzy Komen Award Established to Honor Survivors the National Distance Nominations for the award The first Komen Race for the Running Hall of Fame in will be accepted from Komen Cure® was held in Dallas in partnership with the Affiliates throughout 2001. 1983 as part of a promise Foundation, was unveiled The first recipient of the Nancy Brinker made to her at the Komen West Palm Suzy Komen Award will be sister, Susan G. Komen, who Beach Race for the Cure® announced in 2002 and will died from breast cancer at age event on Saturday, January be honored at a National 36, to do something to fight 27. As the first Race in the Distance Running Hall of this life-threatening disease. 2001 Series, the Komen West Fame induction ceremony in What started as one race with Palm Beach Race for the July of that year. 800 participants is now the Cure® was the perfect forum largest 5K series in the world for the award kickoff. The Komen Race for the with 111 U.S. events. ® Linda Kay Peterson Cure Series is unique in that The National Distance every dollar of participants’ Francie Larrieu Smith, five-time t the start of each Komen Running Hall of Fame, an entry fees goes directly to Olympian and Honorary A Race for the Cure® organization dedicated to fighting breast cancer. Up to Chair of the Komen Race for season, it’s always difficult to advancing the sport of distance 75 percent of net proceeds the Cure® Series, was inducted imagine how we can improve running, partnered with the from each local Komen Race into the National Distance upon the previous year’s Komen Foundation to create for the Cure® stay in that Running Hall of Fame in amazing successes. In 2000, this unique award, which is community to fund non- 1999. The Official Race Series for example, we broke all named in honor of Susan G. duplicative breast health and Partners of the 2001 Komen previous participation records Komen, the inspiration behind breast cancer programs that Race for the Cure® are with more than one million the Komen Foundation and meet the needs of the medically American Airlines, Ford people crossing the finish line the Komen Race for the Cure® underserved. A minimum of Division, Johnson & Johnson in a single year in the Komen Series. This award symbolizes 25 percent of funds raised Family of Consumer Race for the Cure® Series. Suzy’s courage in the fight directly support the Komen Companies, the Kellogg And so, how do we go about against breast cancer and the Foundation Research Company, the National Football improving upon that number strength of the Komen Race Program. During the last 19 League, New Balance Athletic in 2001? We set a goal of more for the Cure® Series in making years, the Komen Foundation, Shoe, Yoplait USA and Zeta than 1.3 million participants. a difference in the lives of due in large measure to the Tau Alpha Fraternity. However, while the number of thousands upon thousands success of the Komen Race participants is important, it is of people each year. for the Cure®‚ has raised in The National Distance the individuals behind these excess of $300 million to Running Hall of Fame, located numbers — the people who In a post-race ceremony in support its mission. in Utica, N.Y., is dedicated to are out there running and West Palm Beach, John honoring the athletes who walking — who make the Petrone, director of the In addition to raising funds have made contributions to Komen Race for the Cure® National Distance Running and awareness for breast the sport of distance running, Series one of the most special Hall of Fame, presented an cancer, the Komen Race (continued on page 7) and unique events ever held. artist’s rendering of the Suzy Series attracts people of all Komen Award to Nancy ages and fitness levels. And in 2001, we will begin Brinker, sister of Suzy Komen Although most participants recognizing some of these and founder of the Komen choose to walk or jog, elite amazing people by establishing Foundation and the Komen runners are also drawn to this a new award to honor breast Race for the Cure® Series. competitive event. All Komen cancer survivors who have The Suzy Komen Award will Race for the Cure® courses advanced the fight against this be housed in the National are certified by USA Track life-threatening disease by Distance Running Hall of & Field (USATF), the participating competitively in Fame next to the Susan G. national governing body for a Komen Race for the Cure® Komen Breast Cancer track and field, long distance event. The Annual Suzy Foundation Race for the running, race walking and Komen Award, established by Cure® Series display. cross-country events. 3 frontline Seven Million Steps Closer to a Cure Lee National Denim Day® Exceeds Goal, Breaks Record he fifth annual Lee individual $5 contributions. This year’s results have already T National Denim eclipsed that record and donations continue to pour in. Since Day® exceeded its goal its founding in 1996, Lee National Denim Day® has raised of raising $6 million more than $23 million for the fight against breast cancer. for the Susan G. Komen Breast Cancer “The Lee Company is a valuable corporate partner of the Foundation and its Komen Foundation, and a valuable partner to everyone who’s fight against breast working to eradicate this disease,” said Nancy Brinker, found- cancer, making it the ing chair of the Komen Foundation. “By collecting more than Gordon Harton, Lee Company president; Susan Braun, Komen Foundation president and CEO; Rob nation’s largest single- $7 million from individual $5 donations, America is sending a Lowe, actor and 2000 Lee National Denim Day® day fundraiser for powerful message that it’s prepared to continue this fight with spokesperson; and Kathy Collins, vice president breast cancer.