Bellwether Magazine

Volume 1 Number 51 Fall/Winter 2001 Article 1

Fall 2001

Bellwether 51, Fall/Winter 2001

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BellwetherTHE NEWSMAGAZINE OF THE UNIVERSITY OF PENNSYLVANIA SCHOOL OF VETERINARY MEDICINE

Salmonella Reference Center Keeping Pennsylvania’s Food Supply Safe PagePage 44

InsideInside BellwetherBellwether 5151 22 FromFrom thethe DeanDean 33 TeachingTeaching && Research Research BuildingBuilding NewsNews 77 SpermatogonialSpermatogonial stemstem cellscells modifiedmodified 88 EquineEquine PregnancyPregnancy LossesLosses inin Pa.Pa. 1212MolecularMolecular PathwayPathway ReportedReported 1616“Renaissance”Vet“Renaissance”Vet 1717V.M.D.NotesV.M.D.Notes 2626SpecialSpecial GiftsGifts toto thethe SchoolSchool

® School of Veterinary Medicine UNIVERSITY OF PENNSYLVANIA Ground Zero, page 14 HeadlineA Message from the Dean n articles and letters discussing those com- disease in animal populations to identify and surveillance, prevention, and control measures ponents of our public health system monitor diseases potentially dangerous to man. aimed at highly contagious diseases that threat- Ideployed to contain the now all too real In the case of West Nile virus infection, the dis- en the nation’s livestock and poultry industries. threat of bioterrorism, veterinary medicine is covery of dead birds first alerted authorities to The agents of foot and mouth disease, avian rarely men- the possibility of ensuing human infections influenza, and swine fever, to name a few, if tioned. Yet and to the need for stringent mosquito control introduced into the , would veterinarians measures. severely damage America’s agricultural econo- are posi- When, in 1993, the Japanese Aum Shinrikyo my and consumer access to affordable supplies tioned to cult released anthrax spores in a Tokyo build- of milk, meat, eggs, and poultry. Large animal contribute to ing, there were no human deaths, but several veterinary practitioners can thwart acts of the health pets succumbed to systemic anthrax, probably agro-terrorism by rapidly communicating sus- and safety of from licking their fur or other objects. In con- picious infectious disease patterns to appropri- human, as trast to cattle, sheep, horses, and pigs, dogs and ate state and federal diagnostic laboratories and well as ani- cats are not highly susceptible to anthrax. agencies, and by imposing appropriate animal mal popula- Nevertheless, these examples illustrate how handling and quarantine measures. tions, in affected animals, if diagnosed early, can serve We must ensure that the same lines of com- uniquely significant ways. Many of the patho- as sentinels of disease, alerting physicians to the munication are readily accessible to veterinari- genic agents believed to be candidates for use possibility of human infection. ans in companion animal practice. by terrorists cause disease in animals and/or In addition to those viral and bacterial Alan M. Kelly are carried by animals. agents of direct public health concern, veter- The Gilbert S. Kahn Dean of Veterinary Medicine Veterinary epidemiologists study patterns of inarians protect our health and welfare by Herb and Ellen Moelis Honored gala reception honoring Herb and Ellen Moelis was held in a flower- Afilled marquee adjacent to the Allam House at New Bolton Center on October 25th. The reception was rescheduled from the American Gold Cup in September, when it was cancelled due to the terrorist attacks on the World Trade Center and the Pentagon. In spite of gusty winds and the threat of falling temperatures, more than 100 people Betty Moran and Leonard King. Betty Moran, Herb and Ellen Moelis. came to celebrate the Moelises, and their many charitable endeavors. In a well- illustrated tribute, Dr. Kelly highlighted Herb and Ellen’s efforts on behalf of the School of Veterinary Medicine, Penn’s Library, Thoroughbred Charities of America, Freedom Hills Therapeutic Riding program and, more recently, the New York Heroes Fund. Herb, a 1953 Wharton School graduate and a member of the Veterinary School’s Board of Overseers, gave a spirited response; Betty Moran,Allaire duPont,Herb and Ellen Moelis. Dean Kelly presents Herb with “Ben on the Bench.” but Ellen touched everyone when she recounted how their grandchildren, who the Moelises have been tutoring in the gentle art September 11th. generous support of New Bolton Center and of philanthropy, spontaneously and Dr. Kelly presented Ellen with a lovely the School of Veterinary Medicine. Everyone unanimously agreed that their own little bouquet of flowers, and then recognized the voted the occasion a wonderful evening of foundation should support the disaster relief tireless efforts of Betty Moran and the fine food, drink and fellowship. fund in New York following the events of American Gold Cup for their continued

2 BELLWETHER 51 CHARTING THE FUTURE

Teaching and Research Building News unds for the new Teaching and The late Mary M. Opsuth of Trenton, N.J., bear her name. Billhardt has served on the Research Building are growing. through her estate, provided at least $500,000 Board of Overseers since 1996. Since August, an additional for a laboratory for medicine clinicians in the Mrs. Emilie deHellebranth, through her F new building. This laboratory will enhance estate, contributed $100,000 for the new $2.5 million has been raised for the the interaction between clinical faculty and Teaching and Research Building. Mrs. building. The total funds raised researchers in the basic sciences. Mrs. Opsuth DeHellebranth, for many years, enthusiasti- stand at $32.5 million, representing was a long-time client at VHUP. She brought cally supported the work of Dr. Peter Dod- two-thirds of the estimated building her poodles in many times to be seen by son, professor of anatomy. She provided cost of $48 million. Meryl Littman, V’75, associate professor of funding for his dinosaur excavation expedi- Several new significant gifts for the new medicine. Mrs. Opsuth so appreciated the tions to Montana and helped underwrite the building include: care her pets received by Dr. Littman and the dig in Egypt that yielded the humerus of Mrs. Ethel Carruth, a 1943 graduate of VHUP staff that she made the provision in Parallatitan stromeri, a giant sauropod. Penn’s School of Education, of Houston, her will, “Because of and as an expression of Planning is proceeding for the new Texas made a gift of $1 million for a laboratory my sincere appreciation for the exceptional Teaching and Research Building as faculty to support the work of the Center for caring talent of Dr. Meryl Littman in the are refining their needs for the much- Infectious Diseases and Food Safety Research. practice of small animal medicine, and in my anticipated teaching and research spaces. Mrs. Carruth and her late husband, Buddy, a memory, I give, devise and bequeath… the 1942 graduate of the Wharton School, have remainder and residue of my estate to the supported the Veterinary School and the School of Veterinary Medicine.”Mrs. Opsuth University for many years. They established died in 1999 at the age of 89. The laboratory $48 million goal an endowed scholarship, the Ethel G. and will be named in her memory. Allen H. Carruth Dean’s Scholarship, in 1992. Board of Overseers member, Patricia Mr. and Mrs. Carruth bred and raised Santa Billhardt, completed her pledge of $250,000 Gertrudis cattle on their ranch in Texas. for a classroom within the new building. Mr. Carruth served for many years as Mrs. Billhardt, a prominent boxer breeder president and chairman of the Houston and exhibitor, and her husband, Jack, are Livestock Show and Rodeo and both were long-time supporters of the School and have very active with the Houston SPCA. established four endowed scholarship that $32.5 million raised Veterinary School Buildings in Philadelphia

Quadrangle Building Gladys Hall Rosenthal Building  

Veterinary Hospital of the Site of Teaching & Research Building The Teaching and Research Building University of Pennsylvania Planned Groundbreaking site is bounded by 38th Street,Woodland   Avenue, and Baltimore Avenue.

BELLWETHER 51 3 Cover Story Keeping Pennsylvania’s Food Products Safe “One in five samples of supermarket ground There are more than 30 antibiotics background and training in reference and meat and poultry bought for study was approved for use in food animals, some of international disease surveillance. Dr. Donald contaminated with Salmonella, and most these drugs are also approved for use in S. Munro retired from the Scottish Salmonella of the strains were resistant to antibiotics.” humans. Bacteria are exposed to these drugs Reference Laboratory (SSRL) in Glasgow and (A report on a scientific paper in the and develop resistance to them. This resistance joined Dr. Benson’s group at New Bolton. He is New England Journal of Medicine, may be transferred in bits of DNA from one an authority on the epidemiology of Salmonel- in The Philadelphia Inquirer, 10/18/01) bacterium to another and between different lae. Dr. Shelley Rankin, also from the SSRL, is ood safety is very much on everyone’s species of bacteria. Such resistance is then experienced in molecular epidemiology. mind. Stories about unsafe foods, food passed on to the next generation and becomes The Center provides diagnostic and refer- Fpoisonings, and rising antibiotic resist- established in the bacteria population. ence service to the PADLS laboratories and ance of organisms, have alarmed the general almonella is the focus of the Salmonella serves the needs of individual practitioners public. Food is no longer locally produced — SReference Center (SRC) which was estab- within Pennsylvania. The Salmonella isolates the marketplace is stocked with fruits and veg- lished five years ago at New Bolton Center samples are typed through a wide variety of etables from far-away states and countries. under the direction of Dr. Benson. Actually, the techniques, including serotyping, phage typing, Cheeses come from across the continent and work on Salmonella at the School began many and antimicrobial resistance monitoring. In Europe. Meat products and fish originate in years earlier when it was realized that table eggs addition, molecular techniques such as plasmid Europe. Fish and particularly seafood is farm- could act as a vehicle for the transmission of profiling, restriction enzyme analysis of the raised in South America and Asia. The raising, Salmonella enteritidis. Dr. Robert Eckroade, bacterial genome and other tests are used to selling and distributing of food is global and associate professor of avian medicine and understand the dynamics of salmonellae trans- this makes it easier for harmful or resistant bacteria to travel from one country to another. Salmonella In response to the recent hoarding of antibiotics by the public, there have been many stories about the ability of Salmonella and other organisms to develop into more and more drug resistant varieties. There is an ongo- ing discussion about drug use in the food ani- mal industry worldwide and about allowing new, powerful antibiotics to be used in the rais- ing of food animals. Each year, millions of Americans suffer from food borne illnesses. Most cause mild dis- comfort, but they can be dangerous for immunosuppressed individuals and the elderly. pathology, and Dr. Benson, conducted many mission. SRC is one of only three laboratories The culprits often are bacteria; Campylobacter studies to determine how the bacteria could in the United States which has the capability causes the highest incidence of illness, followed enter the egg prior to being produced by the and expertise to provide such a detailed analy- by Salmonella, Shigella, and Escheria coli chicken. They also developed a series of pre- sis of the samples. “Using this approach, we H0157. Most Campylobacter infections are ventive measures that farmers employ to have been able to achieve a degree of discrimi- associated with poultry, large numbers of reduce the incidence of Salmonella infection in nation which has been previously impossible to which carry the microbe. Fortunately this chicken houses. These measures have greatly achieve,” says Dr. Benson. “We can not only microbe rarely causes outbreaks with sporadic reduced the number of infected eggs. relate a strain to a given farm, but in some or familial cases accounting for the greatest The Salmonella monitoring program that cases we can even identify which barn.” The number of infections. was developed and put in place at New Bolton Center also performs services for clients out of Is there reason to be worried? “Yes,” says Dr. Center led to the establishment of the SRC state. This yields an enormous amount of Charles Benson, professor of microbiology at which has become a valuable resource, not only research material and generates a healthy the School. “These organisms are all around us. for Pennsylvania farmers, but for other agricul- income. Even if you are a vegetarian, you can get infect- tural laboratories in the nation. The Center is Each sample, once it has been completely ed by Salmonella as the bacteria can be on the part of the Pennsylvania Animal Diagnostic typed, is deposited in the reference laboratory skin of fruit or vegetables grown in a field fer- Laboratory System (PADLS); funding is culture collection together with a complete tilized with manure compost. Bacteria and received from the Pennsylvania Department of record of the test data and available descriptive other harmful organisms have been in the Agriculture, along with grants from USDA, the epidemiology. The collection is available to environment for millions of years and they American Egg Board, and with revenue gener- permit retrospective studies to be undertaken have survived because they can adapt to ated through client services. at such times as new serotypes appear in Penn- changed circumstances rather rapidly.” The Center is staffed by specialists with sylvania. It represents a unique resource to the

4 BELLWETHER 51 state. “The services provided by the SRC pro- adapt them to other genera. This is quite field of human enteric diseases. Its collection of vide an added dimension to the diagnosis and important because there are many organisms more than 17,000 strains of Salmonella from management control of animal associated that threaten the health of food animals and across the United States is a unique asset and human infectious disease and economically humans such as Listeria and Leptospira. enables the laboratory to conduct retrospective important animal diseases within the The SRC works closely with the School’s studies and monitor the development of resist- Commonwealth,” says Dr. Center for Animal Health ance to an enormous range of antimicrobial Benson. and Productivity (CAHP) agents. ne of the important and its field investigators SRC will be one of the founding members Otasks of the SRC is to monitor infectious dis- of Vet-Net, a veterinary monitoring service the monitoring of devel- eases on farms in the funded by the European Economic Commis- opment of antimicrobial region. sion, to be established within two years. Dr. drug resistance which The Commonwealth Benson and his group are a vital part of PADLS poses a major threat to has in excess of 600,000 and they are doing their part of keeping the human and animal dairy cattle and this is one Commonwealth’s food supplies safe. One piece health. Generally it is per- of the state’s main, if not of advice from Dr. Benson: “Wash the fruits ceived that such resistance the largest, agricultural and vegetables before eating them. Cook meat developed because of the industries. In a collabora- and eggs thoroughly. Always wash utensils and addition of antibiotics to tive study of the incidence cutting boards between usage for raw and Dr. Charles Benson animal feeds, often at low of Salmonella infection on cooked ingredients. And enjoy your meal!” levels, to enhance health Pennsylvania dairy farms and growth of food animals. “Not all antibiotic the SRC surveyed 100 randomly chosen farms resistance develops in animals,” says Dr. and found that 14% were positive. Mortality in Benson. “This has been clearly established as a cattle covered by this survey ranged from 1- Scholarships result of the work carried out at the SRC. Every 5%. This indicates that losses due to Salmon- The Dr. Ginnie Leiblein Memorial isolate submitted to us is tested for resistance to ella in the Pennsylvania dairy industry could Scholarship and the Westminster Kennel a range of 13 antibiotics of human and veteri- exceed $6,000,000. Foundation Scholarship were awarded to nary importance. This monitoring allows us to Pennsylvania is unique in that it supports a Patty Lathan, V’02. Amy Balcerzak, V’05 track the development and spread of antibiotic large number of dual enterprise farms. The received a scholarship from the NCAA. resistance throughout the state.”A key conclu- SRC recently completed a study to determine Darah Resh, V’03 received a scholarship sion from this surveillance activity is that resist- the prevalence of Salmonella typhimurium DT from The Lalitta Nash McKaig Foundation. ance is not predicated on a simple cause and 104, a particular drug resistant strain, in the The Barnstable County Agricultural Soci- effect basis. These developments are multi- environment of a naturally infected dual enter- ety, Inc. and The Coondog Scholarship faceted in nature involving a range of complex prise farm. The real-time study allowed for Fund awarded scholarships to Kate interacting factors which include indigenous quick development of recommendations to Johnson, V’03. Emily Kuprion, V’03 flora/dose/time/feed and the innate ability of reduce the incidence and eventually eliminate received a scholarship from the Rotary the pathogen to change. The effects of these the organism from the farm. District 7450 Gundaker Foundation. The factors only begin to become obvious when n most cases, further outbreaks of Salmonella Armour/Lewis Family Foundation provid- large numbers of bacteria are monitored over Ior other bacterial infections can be prevented ed scholarships to Micah Brodsky, V’02, time. This work has attracted considerable by changes in husbandry on the farm. Clini- Annette LePere, V’02, Colleen Kane, V’02, interest, not only within the veterinary micro- cians from the CAHP make recommendations Karena Joung, V’03 and Kimberly biology community, but also within human about disinfection of areas where the animals Johnston, V’03. The William Goldman medicine and the pharmaceutical industry are housed, about feed handling and rodent Foundation has provided scholarships to because of the implications raised. control, to help the farmer overcome the prob- Gina Cairone, V’03, Edward Cooper, V’02, The SRC laboratory has a quick turn- lem. Often it takes just a few changes in prac- Melissa Geedey, V’02, Erin Mairs, V’03 and around time for samples submitted. Serotype tices to eliminate the problem. Karen Oberthaler, V’02. Christine Bohn, and phage type resistance profile can be pro- The SRC collaborates with researchers at V’02 is the recipient of the Clifford R. vided in 24 hours, core molecular data are other universities and laboratories, the Centers Wright, Jr. Scholarship. Marcilyn Duman, available in an additional 24 hours. This for Disease Control, the National Veterinary V’02 was awarded the Iris M. McGee becomes important if an outbreak occurs — Services Laboratory, the National Antimicro- Scholarship. Danielle Springer, V’03 and measures then can be taken quickly to contain bial Monitoring Service and the FDA as well as Kathy Heim, V’04 have been awarded Anne it and to begin preventive steps to protect the institutions abroad. The latter is particularly Linn White Dean’s Scholarships. Frieda other animals on the farm. relevant because of the global nature of food Rest, V’02 is the recipient of the Richard A. The SRC researchers also have the skill to production. SRC is working to become a part Dorr, Jr. Memorial Scholarship. take techniques developed for one genus and of the international surveillance network in the

BELLWETHER 51 5 2001 Rush Shippen Huidekoper Society Dinner he 2001 Rush Shippen Huidekoper Society Dinner, which recognized the TUniversity of Pennsylvania School of Veterinary Medicine’s most generous donors and friends during the 2000-01 fiscal year, was held on Saturday, November 10, at The Academy of Natural Sciences in Center City Philadelphia. Almost 150 guests enjoyed dining in the shadow of dinosaurs in Dinosaur Hall, and attending a presentation by Dr. Peter Dodson, professor of anatomy in the School of Veterinary Medicine and professor of geology in the School of Arts and Sciences. Dr. Dodson enthralled everyone by dis- cussing the recent dinosaur discoveries by him Kenneth L. Bollens, Jr.,V’72, and his wife, Lucille. and his fellow Penn colleagues, including the Dinosaur Hall discovery in 2000 of Paralititan stromeri, the second-biggest dinosaur known to have ever lived. This remarkable discovery in Egypt will be featured in a documentary, The Lost Dinosaurs of Egypt, which will air on the A&E Network in the fall of 2002. Named after the first dean of the School of Veterinary Medicine, the Rush Shippen Huidekoper Society recognizes those donors who contribute $1,000 or above to the School in the fiscal year. The generosity of the School’s alumni and friends advances the School’s mis- sion to better the health and welfare of animals Dr. Peter Dodson, who spoke about recent dinosaur From left to right, James Nutt, V’04, James Jasan, and humans. The continued support of the discoveries. Susan Ackermann, and Monica Hawkins. Mr. Nutt is School’s donors is an important vote of confi- the first recipient of The Jay Jasan Endowed Schol- dence in the School as it continues to build arship Fund, generously supported by James Jasan, upon its more than 100 years of preeminence and other donors, in memory of his son, Jay,V’93. in veterinary teaching, research, and service. For information on becoming a member of the Rush Shippen Huidekoper Society, visit the School’s Alumni & Friends web site at or contact From left to right,David K.Detweiler,C’41 V’42 G’49, Joshua E. Liss at (215) 898-1481 or via e-mail and his wife, Birthe, and Calvin Moon, V’52, and his at . wife, June.

Andrew H.Elser,V’87,(left) and several Opportunity Stuart A. Fox, C’50 V’53, and his wife, Claire, CW’46 St. George Hunt,V’86, and his wife, Susan. Scholarship recipients. GR’66. Photography by Jon Adams/hi5photos by Photography

6 BELLWETHER 51 First Transgenic Animal Developed The Veterinary Hospital of the University of Pennsylvania School of via Retroviral DNA Insertion into Veterinary Medicine Male Germ-Line Stem Cells By Stephen Bradt give rise to skin, the lining of the intestines, Presents Symposia for cientists at the School have successfully brain, muscle and liver. Owners and Breeders used a retrovirus to modify genes in Spermatogonial stem cells are of additional of Companion Animals Sspermatogonial stem cells in a mouse — interest for transgenics applications because the first instance, in any species, of a transgenic they are the only cells, including all other stem animal created by inserting a gene into male cells, that undergo self-renewal throughout an germ-line stem cells. animal’s lifetime and contribute genes to sub- Canine The inserted gene subsequently appeared in sequent generations. Previous attempts to approximately 4.5 percent of offspring of mice genetically alter this unique type of stem cell, transplanted with the altered stem cells, and either through retroviruses or other methods, Symposium was transmitted to at least three succeeding have met with little success. Saturday, January 26, 2002 generations. Brinster’s work is unusual in that his trans- The work was the cover story in the Nov. 6 genic mice were created using cells from male issue of the Proceedings of the National Acade- animals. Transgenic animals are generally pro- Feline my of Sciences. The findings should enable the duced by inserting foreign DNA into cells creation of transgenic individuals in a wide derived from females, such as oocytes, eggs and range of species, permitting scientists to devel- blastocysts. Brinster’s group has demonstrated Symposium op research models for study of numerous that the efficiency of generating transgenic mice Saturday, March 23, 2002 human diseases. through spermatogonial stem cells is roughly Led by Ralph L. Brinster, Richard King equivalent to that of female-derived cells. at the Mellon Professor of Reproductive Physiology “Questions had been raised regarding at the School, the scientists succeeded in insert- whether male germ-line stem cells could be ing a foreign gene — in this case the common transduced with a retroviral vector and Veterinary Hospital of the reporter gene lacZ, whose product is the whether any gene introduced would be University of Pennsylvania enzyme fl-galactosidase — into 2 to 20 percent silenced,” Brinster said. “Our work clearly 3850 Spruce Street of mouse spermatogonial stem cells in labora- demonstrates that the stem cell can be trans- Philadelphia tory experiments, a tenfold improvement over duced at relatively high efficiency and expres- previous attempts. sion is not silenced. About 10 percent of stem “These results indicate that there is no cells carry active genes that are transmitted for Registration for each symposium is intrinsic barrier to the genetic engineering of at least three generations.” $60 per person. spermatogonial stem cells using retroviruses, Retroviruses are the most common vehicles and that once inserted, the foreign genes will for introducing genes in human somatic cell Advance reservations are required. continue to be transmitted and expressed from gene therapy, and some scientists had Seating is limited. For further one generation to the next,” said Dr. Brinster. expressed concern that this approach might information plaese contact: All male mammals harbor many spermatogo- result in genetic alterations to germ-line cells. Josephine Deubler, V.M.D., Ph.D. nial stem cells, key repositories of genetic Brinster’s paper indicates that the germ cells Veterinary Hospital of the material whose daughter cells give rise after are indeed susceptible to insertion of foreign University of Pennsylvania puberty to sperm. In the human male, approx- genes via retroviruses, although the somatic 3850 Spruce Street imately 1,000 sperm cells, each carrying a dif- cells that surround stem cells in the body most Philadelphia, PA 19104 ferent combination of genetic material, are likely provide a protective shield. Tel.: (215) 898-8862 generated in this manner with each heartbeat. Brinster was joined in the work by Makoto Whereas the female germ cell, the egg, stops Nagano, now at McGill University, and Clayton For a detailed program, go to dividing before birth, male germ-line stem cells J. Brinster, Kyle E. Orwig, Buom-Yong Ryu and Of the various types of stem cells, only two Animal Biology at the School. Their work was Reservations can be made electronically — spermatogonial and hematopoeitic stem supported by the National Institutes of Health, by going to the secure website cells — can be positively identified using func- the Commonwealth and General Assembly of for other types of stem cells, such as those that Helen C. Kleberg Foundation.

BELLWETHER 51 7 Equine Pregnancy Losses in Pennsylvania he three-year research investigation enti- A summary of the many aspects of breeding mendations are to administer rhinopneumoni- tled Project M.A.R.E., funded by the farm management was made during Project tis vaccine at 3, 5, 7 and 9 months of gestation TPennsylvania Department of Agricul- M.A.R.E. Breeders seem to be quite successful because the immune protection achieved from ture, was completed in June 2001. Drs. Perry in getting their mares settled as past pregnancy vaccination is short lived and needs to be Habecker, Fabio Del Piero, Tanya Lemire of rates were just over 75%. Although approxi- repeated if mares are to be protected against the Department of Pathobiology at New mately 70% of the farms breed mares by natu- rhinopneumonitis abortion. Three quarters of Bolton Center and Dr. Helen M. Acland of the ral cover, around one third of the farms use the farms use a killed virus vaccine against the Bureau of Animal Health and Diagnostic artificial insemination with fresh semen and herpes virus that causes rhinopneumonitis. Services, Pennsylvania Veterinary Laboratory in slightly more than a third use artificial insemi- Unfortunately some mares do not appear to Harrisburg, Pa. were the pathologists represent- nation with transport- ing the Pennsylvania Animal Diagnostic ed cooled semen. Laboratory System (PADLS) and performing Only 5% of the farms the diagnostic test on specimens. Dr. Patricia L. use frozen semen to Sertich of the Department of Clinical Studies- breed mares. Over New Bolton Center coordinated the project 80% of the mares are and was assisted by the project research techni- examined for preg- cian Mr. Steve Kirschner. Dr. Raymond C. nancy ultrasono- Boston performed the data analysis for the graphically and at project. least 75% of the farms At the onset, the study was assigned a name specifically have their for presentation to the public in order to estab- mares examined for lish study awareness and memorable project the presence of twins. recall. Project M.A.R.E.: Monitoring Abortions If twins are detected & Reproductive Efficiency in Pennsylvania an attempt is made to would summarize certain aspects of breeding manually reduce them management and determine the causes of late on over 80% of the pregnancy loss in mares in Pennsylvania. Horse farms. Some farms breeders and equine practitioners in Pennsyl- allow twins to attempt vania were solicited for participation in Project to regress naturally M.A.R.E. Registration in the study simply but as many as 40% of required a breeder to complete a survey that the farms will terminate twin pregnancies with have adequate immunity as their serum titers inquired about the management of their prostaglandin. In the four years preceding Pro- were found to be low when routine titers were broodmares. Participation in Project M.A.R.E ject M.A.R.E. the farms participating in the evaluated during a pregnancy loss diagnostic entitled the breeder to have a diagnostic evalu- study reported an total average of 29 mares work-up. Close to a third of the breeders do ation and free necropsy of the conceptus of any aborting twins each of those four years. not utilize any veterinary service in maintain- aborting mare. Participating veterinarians lthough two thirds of the farms surveyed ing a vaccination program and instead pur- received information regarding the proper sub- Abreed mares on their home farm, a little chase their vaccines from a mail order service mission of samples from any mare that might over a third of the farms send mares out of and have a layperson administer the vaccines. experience spontaneous abortion. Veterinarians Pennsylvania for breeding. For mares being Although most breeders regularly deworm located in remote areas received fetal necropsy bred off their home farm, both those being their mares during gestation, few took advan- kits complete with a directional video, sample bred in Pennsylvania and out of state, only tage of the effective safe opportunity to vials, and overnight postage. Over 350 breeders about one third return to their home farm in deworm just before breeding when there is no and 135 practitioners registered for the project less than a week after breeding. risk to the fetus and in the first few days after and submitted diagnostic materials from nearly Although only about 6% of the farms never parturition. There is evidence that “foal heat 150 aborting mares. There was a great variation vaccinate their broodmares against infectious diarrhea” can be prevented if mares are admin- in the number of mares each farm managed (1 diseases, most breeders do not provide their istered anthelmintics soon after foaling. This to 500 mares) but most breeders had less than broodmares the best opportunity to produce will decrease the parasite contamination a new- 7 pregnant mares. Most (63%) of the farms did high quality colostrum. Mares are able to pro- born foal is exposed to as they are investigating not have access to a stallion on their home duce higher quality colostrum if they are their early surroundings. Two thirds of the farm. Greater than 23 breeds were represented administered their annual vaccinations at broodmares are administered ivermectin and in the study with the Thoroughbred (32%), approximately one month before their due half of all mares may receive pyrantel pamoate Standardbred (13%) and Quarter Horse (11%) date. More than half of the mares are adminis- during pregnancy. Almost all breeders were being the most frequent breeds represented in tered vaccinations against rhinopneumonitis careful not to administer vaccinations or Pennsylvania. repeatedly during pregnancy. Current recom- anthelmintics during the first month of gesta-

8 BELLWETHER 51 tion when the early embryo is undergoing rhinopneumonitis abortion. It is interesting to be administered antibiotics and agents to help important organ development. Slightly less note that inadequate plasma titers against support the pregnancy. These mares need to be than two thirds of all broodmares have an rhinopneumonitis were found in some of the carefully monitored at the time of parturition annual Coggin’s test performed. Water is sup- vaccinated mares that lost their pregnancy due as the inflamed placenta may fail to rupture plied to the broodmares on most breeding to some other cause. This information reflects spontaneously resulting in delayed delivery of farms as groundwater from wells or springs. the need to investigate the vaccination proto- the fetus and hypoxia. Only 7% use municipal water exclusively for cols that are being used. Prevention of rhino- Pregnant mares should be examined by pal- their broodmares. pneumonitis depends not only on vaccination pation and ultrasonography per rectum at least ortunately more than 75% of the breeders but proper management of the broodmares. two times before 30 days of gestation to Fwere able to submit the entire conceptus Pregnant mares should be isolated from tran- improve the opportunity to detect the presence from mares experiencing a late pregnancy loss. sient horses on the farms and kept in small of twins. Mares found to have twins are best A diagnosis of the cause of pregnancy loss was closed groups. Mares foaling for the first time managed by manual reduction of the twins to a made two thirds of the time if the entire con- should be kept separate from pluriparous singleton prior to 30 days of gestation. ceptus was submitted. Unfortunately, if only a mares. roviding close observation prior to and necropsy kit was submitted, only half of the Efforts should be made to prevent bacterial Pduring delivery can reduce pregnancy loss- time was an etiology determined. Because of infections in mares. Although a diffuse type of es associated with parturition. Good, frequent this finding, breeders should be encouraged to placentitis can occur in mares that develop sep- communications with the farm’s veterinarian take the time and make the effort to send the ticemia, the more common type of placentitis will help assure that obstetrical assistance will whole fetus and the placenta to the laboratory. be available should a When this is not possible though, a necropsy dystocia occur. kit submission is still of value. Most mares had Fortunately brood- no history of problems during their pregnancy mares in Pennsylvania and only a quarter of them appeared ill at the do not appear to be time of their pregnancy loss. The presence of experiencing significant premature lactation or early mammary gland pregnancy loss due to development is thought to be an indication of fescue toxicosis, Nocar- some problem during pregnancy. A third of the dia placentitis, Lep- mares were noted to have mammary develop- tospirosis or the Mare ment before spontaneous abortion. Only 11% Reproductive Loss Syn- of the mares had a history of previous preg- drome that has been nancy loss. Just over 10% of the losses were reported in Kentucky associated with dystocia. this 2001 foaling sea- Problems that were associated with the late son. Project M.A.R.E. pregnancy loss are listed in follow table: has identified problems Placentitis ...... 17% associated with preg- Other placental abnormalities. . 18% nancy loss in mares in Bacteria Infection ...... 12% Pennsylvania. Knowl- Rhinopneumonitis (herpes) . . . 11% is called ascending placentitis and develops edge of this information can help in the organ- Developmental abnormality . . . 11% from a local infection of the genital tract. ization of producer educational programs, Dystocia ...... 10% Mares that have poor perineal conformation or encourage the use of veterinary services to pre- Umbilical cord Abnormalities . . 9% lose significant body condition during preg- vent and treat pregnancy problems, and direct Twins ...... 2.5% nancy may be prone to developing an infection future research projects investigating pregnancy Fescue ...... 0% in the genital tract that slowly moves into the loss. Project M.A.R.E. has identified what Nocardia Placentitis ...... 0% uterus and infects the placenta and may subse- aspects of broodmare management are being Leptospirosis...... 0% quently causes abortion. Changes that occur optimally implemented and what areas need to Equine Viral Arteritis (EVA) . . . 0% with placentitis can be detected and monitored be improved. Veterinarians in Pennsylvania are Equine infectious anemia (EIA) 0% by ultrasonographic examination. Keeping the prepared to provide adequate information and lthough vaccination is recommended to mares in good body condition by providing samples to enhance the Pennsylvania Animal Ahelp protect mares against abortion due to good quality feedstuffs and moderate exercise Diagnostic Laboratory System’s ability to reach rhinopneumonitis, the vaccines are not 100% can prevent this. An episioplasty or Caslick’s a diagnosis. This laboratory and Dr. Sertich effective. In spite of breeding farms carefully Operation can augment the function of the encourage continued collaboration with veteri- following the veterinary recommendations for caudal genital tract to prevent contamination narians and horse breeders in Pennsylvania to frequency of vaccination, vaccine handling and and chronic infection of the genital tract. Monitor Abortions & Reproductive Efficiency administration some mares still experienced Mares showing signs of placental infection may in Pennsylvania.

BELLWETHER 51 9 Dr. Adrian Morrison, professor of behavioral Veterinary Anesthesiologists (ACVA). He and Leslie King, Sarin Sorenmo, and Robert neuroscience, was elected President of the three colleagues from the University of Califor- Washabau,V’82 attended the meeting and World Federation of Research Societies at nia presented three abstracts at the Annual presented papers. its October congress in Punte del Este, Meeting of the American Society of Anesthesi- Dr. Sue McDonnell, adjunct associate profes- Uruguay. Dr. Morrison has been invited to ologists in New Orleans in October. Dr. sor of reproductive behavior, gave a series of present The Walter C. Randall Lecture on Driessen and his co-investigators Drs. Cheung, seminars at the AAEP Encore in Philadelphia Biomedical Ethics in April 2002 during the Jahr and Gunther at the University of Califor- in July; at the Texas Breeder’s Forum, Aubrey, American Physiological Society (APS) Experi- nia received a two-year NIH-BRG grant to Texas, in August; at New Bolton Center in Sep- mental Biology meeting in New Orleans, La. develop new bioengineering methods for the tember; at the Iowa State Veterinary Associa- Recipients of these Distinguished Lectureships in-vivo study of blood substitutes. Dr. Driessen, tion in September; at the AAEP San Diego, Ca., are chosen by the 12 APS Disciplinary Sections Lawrence Nann, technician supervi- and at the Western Equine Reproduction as outstanding contributors and representatives sor, New Bolton Center, and Robin Benton, Symposium in Solvang, Ca. in November. of the best research within their field. The Ran- anesthesia technician, received a grant from Dr. Katherine A. Houpt,V’63,ofCornell Univer- dall Lectureship, sponsored by the APS and Abbott Pharmaceuticals to conduct a clinical sity and Dr. Nancy Diehl,V’91, of Penn State Taylor University, promotes integrity in sci- study comparing two inhalant anesthetics in University, co-taught the two day course at ences, especially to students in training, and horses. New Bolton Center in September. otherwise fosters the highest ethical standards Larry Nann spoke at the Academy of Veteri- The Oncology Service at VHUP was well in biomedical research, publication, teaching nary Technician Anesthetists/ACVA Meeting in represented at the 21st annual Veterinary and interaction with the public sector. Dr. New Orleans, La., in October. His talk, present- Cancer Society meeting in Baton Rouge, La. Morrison’s lecture is entitled “Developing an ed to certified veterinary technicians who per- Drs. Jennifer Baez,V’92, Janet Burke,V’98, Craig Ethical Position on the Use of Animals for form anesthesia on a regular basis, was titled Clifford, Beth Overley, and Ms. Roxanne Biomedical Research.” “Zen and Understanding Your Anesthesia Bachman all presented abstracts at the meeting. Dr. Mark Saunders,V’81, associate professor Machine.” He also organized and taught a wet Dr. Billy Smith, assistant professor in clinical of radiology, was elected studies, presented three as president-elect of the lectures at the annual American College of conference of the New Veterinary Radiology at York State Veterinary the 2001 ACVR Annual Society in November. Scientific Meeting in Rosettes & Ribbons Dr. Jean-Pierre Saint- Honolulu. He will serve some recent accomplishments of note at the School Jeannet, assistant profes- as president-elect for sor of developmental 2001-02 and then move biology, received a three- to president for year grant from the 2002-2003. lab on “Veterinary Anesthesia Machines and March of Dimes Birth Defects Foundation for Dr. E. Neil Moore, professor of physiology, Scavenging Systems.” The meeting was held in a project entitled: “Sox9 activity during neural was elected a Fellow of the American Heart conjunction with and with support from the crest development” Association and an inaugural fellow of the ACVA. Mr. Nann is a member of the Organiz- Drs. Meryl Littman,V’75, Urs Giger and Paula Council on Basic Cardiovascular Sciences of ing Committee of the AVTA. This organization Henthorn received funding from AKC-Canine the American Heart Association. will hold its first certifying exams for Health Foundation for a project entitled: Dr. Ilana Reisner, assistant professor of Veterinary Technician Specialist in Anesthesia “Longitudinal field studies of soft-coated behavioral medicine, was an invited speaker at and Academy membership in October 2002. wheaten terriers affected with protein-losing the“Canine Aggression: A Three Day Sympo- Dr. Alexander M. Reiter, lecturer in veteri- enteropathy and/or protein-losing nepho- sium” in November at the University of nary dentistry, made six presentations at the pathy,” and for the foundation of a DNA bank. Guelph, Ontario. Her talk was entitled “The 15th Annual Veterinary Dental Forum in San role of neurobiology and impulsivity in canine Antonio, Texas in October. Dr.Colin Harvey, aggression. In July, Dr. Reisner was an invited professor of surgery and dentistry, also gave speaker at the AVMA meeting in Boston, and talks at the meeting. He was appointed presented a talk entitled, “Anxiety and its role secretary of the American Veterinary Dental in old dog behavior problems: A no-brainer?” College. Barry Stupine, vice dean of the School, has Dr. Ronald Harty, assistant professor of been named Chair of the Human Resources microbiology, received a five-year grant from Committee and a member of the Executive NIH/NIAID entitled “Budding of Negative- The new date for the European Society of Committee of the American Red Cross, Sense RNA Viruses.” Veterinary meeting in Philadelphia Penn/Jersey Region. The School was well represented at the 7th is September 26 to 29, 2002. Dr. Sheldon Dr. Bernd Driessen, assistant professor of annual FECAVA/FK DVG European Congress Steinberg,V’59, professor of neurology, is the anesthesia, is a diplomate American College of in Berlin, Germany in October. Drs. Urs Giger, organizer. The meeting, originally planned for

10 BELLWETHER 51 Histologic Classification of Epithelial and medicine, presented eight hours of continuing Dr.Brinster honored Melanocytic Neoplasms of the Skin of education seminars at the South American Domestic Animals. Dr.Tom Van Winkle,V’75, Society for Small Animal Specialists meeting in professor of pathology, and Dr. Yvonne Montevideo, Uruguay in November. Schulman, AFIP, presented three hours on Dr. Alicia McKnight, resident in radiology, Histologic Classification of Tumors of the presented a talk entitled “The Feasibility of Nervous System of Domestic Animals Standing Equine MRI-Work in Progress” at the Dr. Robert Eckroade, associate professor of Annual Conference of the American College of poultry pathology, traveled to Mongolia for Veterinary Radiology in Honolulu in August. four weeks in April for ACDI/VOCA as a Vet- Dr. Mark Rondeau, resident in medicine, erinary Curriculum Development Volunteer to won first place in the 2001 Eukanuba Veteri- review the curriculum and to aid in designing nary Diets Case Report Competition. Second curriculum and suggesting changes and areas prize was won by Dr. David Puerto, lecturer in of development. Dr. Eckroade also worked with surgery. government level officials and representatives Dr. Heather DeHeer, staff clinical patholo- of veterinary associations and veterinary edu- gist, is a diplomate of the American College of cators to draft the continuing education Veterinary Pathologists. Dr. Jennifer Bouma, requirement of a veterinary practice act. Dr. V’97, lecturer in radiology, is a diplomate of the Eckroade traveled to Denver, Colorado in June American College of Veterinary Radiologists. The University of Texas M.D. Anderson for a NASDA meeting to evaluate the USDA- Dr. Mark Krecic, lecturer in medicine, is a diplo- Cancer Center presented the 2001 Ernst W. APHIS response to foreign disease outbreaks. mate of the American College of Veterinary Bertner Memorial Award to Dr. Ralph L. Dr.Virginia Reef, professor of medicine, Internal Medicine. Brinster, V’60, Richard King Mellon spoke at the World Equine Veterinary Associa- Drs. Colleen Brady, Deborah Silverstein and Professor of Reproductive Physiology. tion meeting in Sorrento, Italy in October, the Rebecca Syring, all lecturers in emergency and Dr. Brinster was honored for distinguished AVEF meeting in Paris in November and pre- critical care medicine, passed their boards and contributions to cancer research. sented her fifth ultrasound laboratory at the are now diplomates of the American College of The Ernst W. Bertner Award is conferred AAEP meeting in San Diego, Ca. in November Emergency Critical Care. annually on a physician or scientist who has Chung Lee,V’04, has been designated the Dr. Margaret Sleeper,V’93, has accepted the made distinguished contributions to cancer Morris Animal Foundation’s Ballard Student position of assistant professor of cardiology. research. Established in 1950, it is the oldest representative. As a Foundation ambassador, a Dr. R. Avery Bennett joined the faculty at award conferred by the M.D. Anderson Ballard Student works to educate the student VHUP in December as associate professor of Cancer Center. It is presented at the annual body and the faculty at the veterinary schools surgery. Symposium on Fundamental Cancer about the Foundation’s vital role in advancing Dr. Jennifer l. Baez,V'92, lecturer in Research. veterinary medicine oncology, is a diplomate of the American Dr. Reid Groman, lecturer in critical care College of Veterinary Oncology.

September 2001, had to be postponed. Dr. Shelly Rankin, assistant professor of microbiology, received a two-year grant from Penn Approved as ECVDI Training Center the Commonwealth of Pennsylvania Depart- The European College of Veterinary Diagnostic Imaging (ECVDI) has recently approved ment of Agriculture to study “Genotypic Characterization of Antibiotic Resistant the University of Pennsylvania School of Veterinary Medicine as an official residency training Salmonella.” center in diagnostic imaging. The ECVDI is the analogous European organization to the Dr. Phillip Scott, professor of microbiology American College of Veterinary Radiology (ACVR). and immunology, received the Bailey K. The University of Pennsylvania is the first ECVDI training center in America. Dr. Tobias Ashford Award by the American Society of Schwarz, who is a diplomate of the ECVDI, and Dr. Jeff Wortman, who is a diplomate of the Tropical Medicine and Hygiene. The award, ACVR, co-direct the ECVDI residency program. which recognizes distinguished work in the It is now possible for the School’s radiology residents to simultaneously fulfill the require- tropical medicine field, was presented at the ments to sit for both the ACVR and the ECVDI certifying examinations in the third year of the annual meeting of the American Society of residency. This ECVDI residency program is another example of the strong European bonds Tropical Medicine and Hygiene in Atlanta, Ga. in November. with the University of Pennsylvania School of Veterinary Medicine. At the First Annual C.L. Davis/AAVLD Two first year radiology residents, Dr. Yael Mosenco and Dr. Allison Zwingenberger,have Diagnostic Pathology Symposium in already enrolled in the ECVDI residency program. November Dr. Michael Goldschmidt, professor More information about ECVDI can be found under: http://www.vet.gla.ac.uk/EVDI/ecvdi.htm of pathology, presented three hours on

BELLWETHER 51 11 First Molecular Pathway Known to Regulate Rest and Wakefulness By Stephen Bradt for us, we can start to think of how to control, already known to function in cyclic AMP sig- orking with sleep-deprived fruit flies, manage and improve sleep,” said Hendricks, naling, is also known to play an important role scientists at the University of Penn- the Corinne R. and Henry Bower Professor of in learning in fruit flies. Hendricks’ work could Wsylvania have uncovered the first Medicine at the School. “This would be helpful strengthen the link that many researchers molecular pathway, in any species, implicated for people subjected to changes in sleep sched- believe exists between rest and the consolida- in the shift between rest and wakefulness. ules and for people with sleep disorders.” tion of memory. The findings, from a team led by Joan C. Hendricks’ group first described Drosophila The Penn group is continuing its studies of Hendricks of Penn’s Center for Sleep and sleep in a paper published last year in the jour- how CREB is turned on, as well as the target Respiratory Neurobiology were reported in the nal Neuron. Rest in flies shares numerous simi- genes affected by its activity. They suspect that November issue of the journal Nature larities with human sleep, including prolonged CREB activation during rest may somehow Neuroscience. The work indicates that a immobility, decreased sensory responsiveness optimize the function of the central nervous Drosophila melanogaster gene known as CREB and a need to compensate after sleep depriva- system during waking hours. — evolutionarily conserved in species from tion. Fruit flies spend about six to 10 hours a Hendricks’ co-authors on the Nature flies to humans — plays a role in rest’s rejuve- day resting, mostly at night. Neuroscience paper are Julie A. Williams, Karen nating effects, apparently permitting sustained “The sleeping flies lie prone in a quiet Panckeri, David Kirk and Amita Sehgal,all of wakefulness. corner, unresponsive to stimuli, for bouts Penn, and Marcela Tello and Jerry C.-P.Yin of Anyone who’s ever pulled an all-nighter averaging about 45 minutes but sometimes the Cold Spring Harbor Laboratory in New knows by the next morning that sleep is essen- lasting up to two-and-a-half hours,” Hendricks York. Their work is funded by the National tial, and sleep’s status as a behavior found in said. “These sessions are interspersed with very Institute of Heart, Lung and Blood and the organisms ranging from fruit flies to frogs to brief, one- to two-minute interruptions, Howard Hughes Medical Institute. humans underscores its importance as a bio- during which they eat and groom and then logical process. But 50 years after the discovery settle back down.” of REM sleep, scientists still know little, on a The Penn researchers’ new findings indicate molecular level, about why sleep is needed and that the activity of CREB, short for cyclic AMP the exact benefits conferred by a daily period of response element binding protein, is inversely rest. related to the physiological urge for rest. The The Penn researchers say that in addition to need for sleep after a phase of deprivation — offering answers to such fundamental ques- attained through the mechanical agitation of ® School of Veterinary Medicine tions, the new work could help improve the fly habitats roughly every 15 seconds for as UNIVERSITY OF PENNSYLVANIA efficacy and safety of the ways people alter their long as six hours — surged in flies whose sleep patterns. CREB activity was blocked. In normal flies, “If we can get at basic mechanisms of how CREB activity remains elevated for some 72 Visit the School of sleep is normally controlled, and what it does hours after such a prolonged period of wake- fulness; CREB mutants slumber even longer Veterinary Medicine’s than normal flies in the aftermath of redesigned web site at Director of Development deprivation. CREB, which is evolutionarily conserved in www.vet.upenn.edu for VHUP Appointed species from slugs to mice to humans and Donna M. Carlson has been appointed director of development for VHUP. Ms. Carlson Cystinuria Study in the Maned Wolf served as director Dr. Paula Henthorn, associate professor of medical genetics, received a three-year grant of development for from the Morris Animal Foundation to continue studies of cystinuria in the maned wolf. The Eagleville Hospital maned wolf, a threatened South American canid species, has a high incidence of this hereditary for three years. Pre- disease that results in cystine stone formation. The study is an extension of the ongoing studies viously she was in of cystinuria in dogs. The preliminary studies were carried out by James Kehler, V’02,a student several positions in the School’s V.M.D./Ph.D. program. It is worth noting that Dr. Kenneth Bovee studied over a six-year peri- cystinuria in the maned wolf back in the 1970’s and 1980’s, and that the Metabolic Screening od at Holy Family Laboratory in the Section of Medical Genetics has been providing urine screening for the past College. She received her undergraduate 20 years as a service for North American zoos and wildlife sanctuaries that maintain maned degree in economics from Holy Family wolves. The current studies are an extension these previous studies, and we can now use College. Donna owns a great Pyrenees molecular genetics approaches to understanding the disease. and has been a VHUP client.

12 BELLWETHER 51 Opportunity Scholarship Program Impacts Students and Donors by Joan Capuzzi Giresi,C’86 V’98 $10,000 is at least $15,000 on payback,” she says. Drs. Smith and Craig met Ms. Moore at the or Diana Chang, V’05,receiving an Opportunity Scholarships also benefit the 2001 Rush Shippen Huidekoper Society dinner, Opportunity Scholarship to the Univer- School, explains Dr. Raker, by luring competi- held in recognition of those donors who con- Fsity of Pennsylvania School of Veterinary tive students who might otherwise not consider tribute $1,000 or more to the School in the fis- Medicine has been much more than a badly- Penn due to its high tuition in comparison to cal year. The event, held November 10 at the needed source of financial aid. It has been a the public veterinary Academy of Natural sense of gratification. schools. “By offering some Sciences in Philadel- “It’s a great honor because it’s like someone scholarship aid, we can phia, also featured a reaching out their hand to you to help you maybe turn the tide and presentation by Dr. along. It’s an amazing feeling,” says Ms. Chang. have them come to Penn Peter Dodson on The Opportunity Scholarship Program and not go to some other recent dinosaur dis- pairs each donor, who commits to giving veterinary school.” coveries. $2,500 per year for four years—a total of Scholarship donors Dr. David P. $10,000—to a single student, who is selected may submit preferences Martin, V’66,who based on strong academic qualifications and for their recipient stu- met his and his financial need. Since the program’s inception in dents, which aids in wife’s student recip- 1998, 40 Opportunity Scholarships have been enhancing the mentoring ient, Ms. Hennessey, relationship. For example, at the dinner, says awarded. The Martin Family Opportunity Scholarship Dr. Charles W. Raker, C’41 V’42, chairman Ms. Chang’s sponsors, From left to right, David P.Martin,V’66, Mary Ellen the scholarship pro- of the Opportunity Scholarship Program Com- spouses Drs. Andrew P. Hennessey,V’05, and Ulrike Martin. gram provides an mittee, adds that the beneficiaries are “students Nebzydoski, V’84, and added benefit to Patricia A. Morgan, V’85, asked that their stu- donors: “It caught my imagination as some- dent recipient be from Northeastern Pennsyl- thing that was really neat to see in a single per- vania and be interested in large-animal work. son rather than to just give money that goes Each student in the program is also paired into this big nebulous pot.” with a mentor who is either his or her donor(s) Craig, who recalls that the tuition cost was or a faculty member. Dr. Raker, for example, just $165 a semester when he went to veteri- has offered advice on summer jobs in the vet- nary school, is pleased with the opportunity to erinary field provide essential tuition to the stu- assistance to Ms. Moore. dent whom “The help she’ll get from he sponsors this will not only benefit and men- her now,” he says. “It’s tors. In his really going to launch The Henry and Mary Nebzydoski Opportunity Scholarship From left to right, Andrew P.Nebzydoski,V’84, Diana mentorship her future.” Chang,V’05, and Patricia A.Morgan,V’85. of a second As for the future of student— the Opportunity who we feel would be a credit to the profession whose Scholarship Program, and to the alumni of the University of sponsor is the original 13 scholar- Pennsylvania.” not a veteri- ship recipients will grad- For Ms. Chang, a Taiwanese immigrant who narian—Dr. uate this year. Dr. Raker Raker hopes Jon Adams/hi5photos by Photography and his fellow commit- is funding her veterinary education entirely on The Spring Mills Veterinary Hospital Opportunity Scholarship student loans and scholarships, the award has to help the From left to right, Suzanne J. Smith, V’82, Peter H. Craig, V’55 tee members are already meant not having to work part-time while in third-year G’58,Michael Craig,and Brooke Moore,V’05. contacting the donors of school. Opportunity Scholarship funds have student in those scholarships to also spared Mary Ellen Hennessey, V’05,from his pursuit of an equine residency. renew their support, and they hope to add on having to juggle school and a job. “I need all Dr. Suzanne J. Smith, V’82—who, with her ten new scholarships this year. the time I have to study,” she says, “and I know husband Dr. Peter H. Craig, V’55 G’85,spon- Joan Capuzzi Giresi is a writer and a veterinarian in I couldn’t do it with a job.” sors and mentors Ms. Moore—hopes the stu- the Philadelphia area. Recipient Brooke Moore,V’05, who is also dent spends some time at Dr. Smith’s mixed- borrowing the entire tuition amount, less schol- animal practice in Milford, N.J. “I hope this is a For more information or to receive a brochure on the Opportunity Scholarship Program, please contact arships, notes that the financial benefit of her place she can run to when she needs to get Joshua E. Liss, Director of Alumni Relations and Opportunity Scholarship is far greater than the reanchored to where her future is going to lead Annual Giving, at (215) 898-1481 or via e-mail at face value of the funds. “With interest, that her in practice,” she says. .

BELLWETHER 51 13 VHUP Clinician Serves at Ground Zero t 1:00 PM on September 11, Dr. Cynthia Otto, go to work.” associate professor of emergency and Teams at disaster sites Acritical care medicine at VHUP, stopped are put under the com- her hospital routine and became a government mand of the local authori- employee for nine days. Dr. Otto, a member of ties. Here it was the New the Pennsylvania Task Force 1, one of 28 Urban York Fire Department. Search and Rescue Teams in the nation, was The team was divided into “activated” to be deployed to the destroyed two work groups, the day World Trade Center complex in New York. shift and the night shift. The team of 62 people is trained to deploy Dr. Otto became part of in six hours, self sustain for 72 hours, and oper- the night shift because it ate 24 hours a day. The team and the dogs are was decided that local vet- specifically trained for search and rescue after a erinary care would be building collapse. Teams were established by the harder to obtain during Federal Emergency Management Agency to be the night. Two dogs, deployed after natural disasters such as hurri- Logan, a German shep- canes and earthquakes. The Pennsylvania Task herd, and Bear, a Labrador Force has been in existence for eight years and retriever, were on the shift. was first deployed during Hurricane Floyd. A The team had a forward team is made up of search and rescue, medical, base of operations in the technical and logistics personnel. There is no Merrill Lynch Fitness official team position for a veterinarian, but the Center at Ground Zero. experience in New York shows how necessary a The space had been dam- veterinarian is at a disaster site. The team aged, but it was function- includes four highly trained search dogs and al. The base was in close their handlers, firefighters specially trained for proximity to that of the rescue, paramedics and physicians. New Jersey team, so Dr. “After a delay at the Lincoln Tunnel for a Otto kept an eye on their bomb scare, the team arrived at the base of dogs and other dogs that A quick nap operations, the Javits Center, about midnight,” were in need of care. said Dr. Otto. “We unloaded our two semi- “What was a typical he conditions under which dogs and peo- trailers of gear and equipment and set up an night at Ground Zero?” said Dr. Otto. “The Tple worked were dangerous. They had to impromptu home. By 3 AM we were ready to night shift would load up on buses or military maneuver on a huge pile of building debris, vehicles for the trip to Ground where gigantic steel beams rested precariously, Zero. The streets were lined with one on top of the other. They had to watch New Yorkers cheering on the their footing and be prepared for sudden holes. workers. It was a powerful way There was smoke, noise of huge cranes and to start a shift. The busiest com- hauling equipment, dust, and a great variety of ponent of the team was the odors. Everything was bathed in incredibly search component, the dogs and bright light from the many high-powered lights also technical search (using spe- on the site. The humans wore masks and pro- cialized search cameras and lis- tective shoes and clothing. The dogs could not tening devices). The dogs would have masks nor could they work in booties — be sent out to the “pile” with the thousands of which had been donated by a handler. They would search areas well-meaning public — because they needed to of rubble looking for live vic- feel the terrain with their feet to avoid tims. Although they are trained accidents. for “live find,” it soon became The dogs were constantly called to search evident that the dogs were also and this contributed to dehydration and able to identify remains of exhaustion. “I gave a lot of fluids, subcutaneous victims.” and IV,” said Dr. Otto. “We tried to rest the Dr. Otto examining a dog in distress

14 BELLWETHER 51 Dr. Otto said that the country was incredible. Daily we would receive rare critical animal was emails of support, letters from children and evacuated to the Animal encouragement from strangers. The Spirit of Medical Center, New America has risen and will not be beaten down.” York City. She said that There were approximately 350 dogs in “Despite all of the risks, Manhattan working at Ground Zero. They the dogs had minimal made around 900 visits to the mobile VMAT problems. The biggest clinic. Some of these dogs belonged to the 21 problem seen was dehy- Urban Search and Rescue Teams deployed dration, probably a result there. Five such teams were deployed to the of overwork. Cut pads Pentagon site. Dr. Otto observed the conditions were remarkably infre- at the site first hand and worked in the dust, quent despite the sharp smoke, and air full of noxious odors coming debris. The dogs were from a myriad of burning chemicals and sub- tired and because they stances. The long term effect of such exposure were not finding live vic- remains to be seen. Dr. Otto has designed a tims, they did not have three-year study to follow the dogs who opportunity to play, their worked at Ground Zero to determine whether normal reward for a the exposure at the site will affect the dogs’ find.” health in the long term. The study will be To keep the dogs’ funded by the American Kennel Club, the AKC spirits up, the team Canine Health Foundation, Ralston Purina, organized searches in a and Veterinary Pet Insurance. near-by park. A person These dogs, in addition to their work right would hide and the dog after the disaster, may contribute in the future would find it. Then it in their role as sentinels for health problems was playtime. “Many that may be encountered later by the firemen, people volunteered to policemen, the rescue personnel, and the con- Taking a break with one of the dogs hide,” said Dr. Otto. “It struction workers who worked at the site from gave them a release and the beginning. One can only hope that the dogs as much as possible and get them to drink it helped the dogs. The effects will be minor and not long term. The water. These are very intense dogs, they are dogs also became therapists to the many people study may provide answers in three to four driven and will work until they drop. So dehy- who worked at Ground Zero. They were petted years. dration was a big danger. The other dangers and talked to, they momentarily distracted were the dust and the noxious fumes. I rinsed people from the horrendous scene. The need their eyes every 30-45 minutes. Their feet too for this interaction led to therapy dogs being were washed at that time to flush away the fine brought to Ground Zero to interact with the dust. I bandaged wounds and treated minor rescue personnel.” cuts on site. More serious problems were treat- The night shift ended around 8:30 AM ed by the Suffolk County, N.Y., SPCA van that when the team was transported back to Javits was used by the Veterinary Medical Assistance Center for rest. The dogs went to sleep pretty Team (VMAT), located about five blocks from easily, but the humans did not. They were Ground Zero.” camped out on the floor, in sleeping bags — it The VMAT team is one of four that exist in was light, noisy and busy. “We got about three the nation, these teams are based in Massachu- to four hours of sleep each day before we start- setts, Maryland, North Carolina and . ed our shift again,” said Dr. Otto. They are made up of 15 to 20 veterinary per- he tour of duty ended on September 19th sonnel. The team also provided a decontamina- Twhen the Pennsylvania team was relieved by tion facility where the dogs were bathed at the a team from Texas. “It was a hard time, but a end of each shift to remove the dust and debris powerful time,”said Dr. Otto. “The swell of sup- from their coats. port from the citizens of New York and the entire Decontamination

BELLWETHER 51 15 V.M.D.NotesV.M.D. NOTES V.M.D. V.M.D.Notes NOTES V.M.D. V.M.D.Notes NOTES V.M.D. NOTES V.M.D.Notes V.M.D. NOTES V.M.D.Notes V.M.D. NOTES “Renaissance”Vet Offers Perspective on Diverse Career by Patrick A.Mahaney,V’99 training coordinator for the laboratory animal Life Sciences, providing services to the under- r. Sally Walshaw’s interest in all animal unit at MSU. She views “teaching as a joy and graduate, medical, veterinary, and nursing col- species has provided her a life of privilege.” Currently, she is an associate profes- leges. In 2000, she became the acting director Ddiverse experiences in veterinary medi- sor of small animal clinical sciences, teaching of University Laboratory Animal Resources at cine. She is currently the acting director of undergraduate, graduate, post-doctoral, and MSU, involving the management of laboratory University Laboratory Animal Resources at veterinary students to refine their laboratory animal care. She oversees an outreach program Michigan State University. Dr. Walshaw grew promoting up in Nebraska, moved to New York as a high public under- school senior, and received her B.A. in biology standing from Manhattanville College in Purchase, N.Y., about labora- in 1966. Dr. Walshaw worked as a lab assistant tory animal in biochemistry for the Sloan-Kettering Cancer medicine Institute in , where an advisor through tours suggested she further her education through a of the facili- master’s degree. ties. As a In 1968, she received a M.A. in biology from writer, Dr. Hunter College in New York City. Dr. Wal- Walshaw has shaw’s graduate work developed her interests in co-authored comparative biology, such as species character- Manual of istics, physiology, and ecology. Her interest in Clinical Proce- becoming a veterinarian stemmed from her dures of the perception that “veterinary medicine offered a Dog, Cat, and scholarly opportunity and a practical approach Rabbit,con- to problems in various animal species and tributed chap- ecosystems.” ters on Rabbit Dr. Walshaw then pursued a veterinary edu- Behavior and cation as an in-state applicant to Cornell Uni- Rabbit Photo courtesy of Greg DeRuiter,Lansing courtesyPhoto of Greg Journal State versity. According to Dr. Walshaw, a professor Euthanasia in on Cornell’s admissions committee told her, animal techniques. Students and faculty prac- the Manual of Rabbit Medicine and Surgery, “you have an excellent academic record, it’s too tice first on a variety of models, such as home- and published articles in scientific journals. bad that you are a woman.”Although her first made, baby-sock, mice models, before per- r. Walshaw lives with her husband, choice school rejected her at a time when forming procedures on research animals. DRichard, whom she met during his resi- women were not admitted in large numbers to y comparing experiences with her Penn dency in small animal surgery at Penn. Richard veterinary school, Dr. Walshaw was Penn’s gain Bclassmates, Dr. Walshaw realized the is the section chief of Small Animal Surgery in 1971. importance of the human-animal bond among and a professor in the Department of Small As a student, Dr. Walshaw felt that Penn’s those who enter the field of veterinary medi- Animal Clinical Sciences at MSU. They have a veterinary program was designed to “give her cine. She finds “many aspects of the bond fasci- daughter, Patty, who graduated in 2001 from the best education possible,” and she enjoyed nating,” considering that the bond is not exclu- Penn and who is now studying at Temple Uni- positive experiences through the School’s facul- sive to any particular species. Involved with versity to be a psychologist, and a son, Dan, ty-student mentoring program. She viewed her human-animal bond activities since 1981, Dr. who is in high school. Dr. Walshaw looks for- elective classes and rotations as opportunities Walshaw has been the secretary for the Ameri- ward to retirement, as she hopes to study Span- to optimize her limited experiences with large can Association of Human-Animal Bond Vet- ish and an Asian language. Additionally, she animal species. Dr. Walshaw received her erinarians since 1997. She also provides presen- intends on further exploring her interest in all V.M.D. in 1975, and completed a small animal tations on animal death and human emotion species through hiking and aquatics expedi- internship at Penn in 1976. for pet owners, veterinarians and veterinary tions. Dr. Walshaw explored clinical work at a pri- technicians, laboratory animal workers, and animal shelter workers. In addition, she has a Patrick Mahaney is a veterinarian practicing vate practice in Michigan, and then began her emergency medicine and surgery in Rockville, Md. long-standing association with Michigan State strong interest in the humane treatment of lab- Patrick lives in Washington, D.C., and enjoys the city's University (MSU), teaching in the veterinary oratory animals. many cultural offerings and yoga studios. technology program from 1978 to 1987. In Dr. Walshaw also is an adjunct professor in 1987, Dr. Walshaw accepted the position of the MSU Center of Ethics and Humanities in

16 BELLWETHER 51 V.M.D.NotesV.M.D. NOTES V.M.D. V.M.D.Notes NOTES V.M.D. V.M.D.Notes NOTES V.M.D. NOTES V.M.D.Notes V.M.D. NOTES V.M.D.Notes V.M.D. NOTES President’s Message Class Notes am privileged to have the honor to work time in more than six years. A fun-filled day 1939 on behalf of the School of Veterinary is planned that will include a continuing Martin H. Ravitch and his wife, Reba, were IMedicine’s alumni as the 2001-03 education course, VMAS Annual Meeting, recently profiled in a San Antonio Community president of the Veterinary Medical Alumni Alumni Day Picnic, participating in the Hospital publication as contributors to the Society (VMAS). I Parade of Classes, tours of VHUP, and an all- hospital in Upland, Calif., where they have lived am a small animal alumni dinner honoring the 2002 reunion since 1976. According to the article, the practitioner in the classes (years ending in “2” or “7”) at the Ravitches traveled on more than 100 cruises New York City University of Pennsylvania Museum of during the 1980s. area, and the son Archaeology and Anthropology. We hope of Jack Bregman, that all of you will appreciate this change of 1945 V’66. scenery, and will make plans to join us on Jack K. Robbins, his wife, and their four We have a Friday, May 10-Saturday, May 11. For more sons, who are all active in the horse racing wonderful group information, see page 21. industry, received the Commissioner’s Cup of alumni who The School is experiencing a wonderful from the National Thoroughbred Racing Asso- serve on the period of growth. There are several projects ciation (NTRA) in November 2001. The Com- Eric M. Bregman,V’95, missioner’s Cup is presented annually to honor VMAS Executive President,Veterinary underway, including the renovation of the Board, including Medical Alumni Society VHUP wards and the construction of the an individual or group for extraordinary con- several new mem- new Scott Equine Sports Medicine Building tributions to the NTRA and the Thoroughbred bers who are recent graduates from the at New Bolton Center. All of this work, along industry. According to NTRA Commissioner 1990s. This year’s new members are with the planned new Teaching and Research Tim Smith, “Jack Robbins has been a key sup- Kimberly Dawn Ashford, V’97; Stephen P. Building, will greatly benefit the education of porter during the NTRA’s creation and devel- Butler, V’84; St. George Hunt, V’86,who today’s students. opment, and his family’s contributions— serves as the alumni representative on the In conclusion, I would like to say that I whether on the racetrack, in executive offices or School’s Admissions Committee; Anita am very pleased and proud to be working on in the legal realm—offer further evidence of Impellizeri, V’97; Lori Spencer Mann, V’95, your behalf for the next two years. We appre- why this extraordinary family was chosen for who serves as the alumni representative on ciate any input that you may have. Please feel this award.” Dr. Robbins is a longtime equine the School’s Long Range Planning Commit- free to contact me via e-mail at practitioner at California racetracks. He is a tee; Shannon D. Shank, V’99; and James V. with your comments member of the The Jockey Club and a director Stewart, V’68, who is president-elect of the and suggestions. For more information on of the Grayson-Jockey Club Research Founda- VMAS and is the chairperson of the Alumni the VMAS, please visit the School’s Alumni & tion. Dr. Robbins is a past president and a Dis- Liaison Committee. Friends web site at tinguished Life Member of the American Asso- A new development for the upcoming . ciation of Equine Practitioners. year is a change in location for Alumni I hope to see many of you at the Penn Weekend. The Executive Board is excited to Annual Conference in January. Have a won- 1956 announce that Alumni Weekend 2002 will be derful holiday season and a happy new year. Elizabeth Atwood Lawrence made a held in Philadelphia exclusively for the first continued on page 18

Class of 1981 20th Year Reunion On September 29, 2001, members of the Class of 1981 celebrated their 20th year reunion at the home of Michael J. Herman, V’81, and his wife, Janice, in Worcester, Pa. Those in attendance included, from left to right, Paul V.Marino, V’81, and his wife, Anna-Ghilaine Schless; David K. Lukof, V’81; Dolores M. Holle, V’81, Pamela J. McKelvie- Smith, CW’75, V’81; Richard M. Levine, V’81, Michael J. Herman, V’81, Mark D. Newkirk, V’81; and Judith A. Durkee, V’81.

BELLWETHER 51 17 V.M.D.NotesV.M.D. NOTES V.M.D. V.M.D.Notes NOTES V.M.D. V.M.D.Notes NOTES V.M.D. NOTES V.M.D.Notes V.M.D. NOTES V.M.D.Notes V.M.D. NOTES Class Notes presentation, “The History of Livestock Pro- has served as president of the Jacksonville recognition of outstanding and prolonged jects in Developing Countries,” during the Veterinary Medical Society twice. service to the College. annual meeting of the American Veterinary Medical History Society at the American Vet- 1960 1970 erinary Medical Association (AVMA) Annual Walter M. Woolf was also recognized by the During the Pennsylvania Veterinary Medical Convention in July 2001. FVMA with a Lifetime Achievement Award at Association’s (PVMA) Annual Meeting in its annual convention in September 2001. Dr. August 2001, John I. Enck, Jr., was elected 1957 Woolf has served as president of the Hillsbor- President-Elect. He is the Director, Bureau of M. Phyllis Lose, who has practiced equine ough County Veterinary Medical Society and Animal Health and Diagnostic Services, and medicine for the last 45-years in Bensalem, Pa., the Pinellas County Veterinary Medical Society. Executive Director, Animal Health and and who has authored several equine books, is He and his wife, Millie, also own Air Animal, Diagnostic Commission, Pennsylvania Depart- the owner of Oscar, a small white mixed terrier, Inc., an animal transportation company. Dr. ment of Agriculture. He also serves as the State who will be starring in a new motion picture, Woolf has been active in this industry, serving Veterinarian. “Crimebusters,” to be filmed at Universal Stu- as president of the Independent Pet and Ani- dios in Orlando, Fla. mal Transportation Association, and currently 1974 as president of the Animal Transportation During the PVMA’s Annual Meeting in 1958 Association. August 2001, Theodore B. Robinson was hon- The Florida Veterinary Medical Association ored with the 2001 Veterinarian of the Year (FVMA) honored Russell J. Snyder with a Life- 1966 Award. He was recognized for his dedication time Achievement Award at its annual conven- Suzanne Ruch Jenkins received the 2001 and service to the veterinary profession tion in September 2001. The award is given to Helwig-Jennings Award from the American through his work with the Bucks-Montgomery senior members who have made outstanding College of Veterinary Preventive Medicine dur- Veterinary Medical Association, PVMA Winter contributions to the FVMA and veterinary ing its annual meeting at the AVMA Annual Seminar, and the Crown Point Navajo Indian medicine. Dr. Snyder has been an active mem- Convention in July 2001. The award is given in Reservation in New Mexico. ber of the FVMA since he joined in 1960, and 1977 Sydney Evans was appointed an associate AAEP Annual Convention professor of radiation oncology by the Universi- Alumni Reception ty of Pennsylvania School of Medicine in More than 60 School of Veterinary Medi- December 1999. She was selected to serve on cine alumni and their guests attended an alum- Penn’s Faculty Senate Executive Committee and ni reception during the American Association Medical School Executive Committee in 2001. of Equine Practitioners’ 47th Annual Conven- tion in San Diego on November 25, 2001. Penn 1978 alumni enjoyed the opportunity to renew old Richard S. Freedman is one of 14 new vet- friendships and make new ones at the largest From left to right, Dr. Virginia Reef, professor of erinarians to be inducted into Morris Animal equine veterinary meeting in the world. Dean medicine and chief, Section of Sports Medicine and Foundation’s Veterinary Honor Roll. Honorees Alan M. Kelly gave alumni an update on recent Imaging, at New Bolton Center, J. Clyde Johnson, are nominated by donors who contribute $500 V’62, and his wife, Ruth. activities at their alma mater. or more to the Foundation on behalf of the vet- erinarian. “These veterinarians were recognized by their clients for providing service over and above what they would typically expect in vet- erinary care,” said Dr. Robert Hilsenroth, execu- tive director of Morris Animal Foundation. Dr. Freedman practices in Charlottesville, Va. 1980 Carol Zoltowski has been recently appoint- ed Vice President, Regulatory Affairs at VIVUS, Inc., a pharmaceutical company engaged in the From left to right, Dean Kelly, Florence Brennan, From left to right, Dr. Alexandra Konegger; Jack M. and Bernard F.Brennan,V’46. Leonard,V’79; and Dr. John Lee, Jr. development of innovative therapies for the

18 BELLWETHER 51 V.M.D.NotesV.M.D. NOTES V.M.D. V.M.D.Notes NOTES V.M.D. V.M.D.Notes NOTES V.M.D. NOTES V.M.D.Notes V.M.D. NOTES V.M.D.Notes V.M.D. NOTES Class Notes treatment of quality-of-life disorders in men 1993 and women, with a focus on sexual dysfunc- Deaths Alexandra L. Chisolm-Chait has become tion. In addition, she continues relief work as a board-certified in Internal Medicine-Small clinical veterinarian in San Francisco. 1935 Animal by the American College of Veterinary Elwood G. Fooder on April 14, 1999. 1985 Internal Medicine. Dr. Chisolm-Chait practices Arnold M. Snyder on September 19, 2001. at the Pet Emergency & Specialty Center in La James A. Thomson, a University of Wiscon- Mesa, Calif. sin-Madison developmental biologist, was pre- 1937 sented with the Wilson S. Stone Memorial 1995 James G. Eagelman on August 12, 2001. Award in October 2001 at the 54th Annual Mary A. Bryant was elected to a three-year Symposium on Fundamental Cancer Research 1940 term to the American Veterinary Medical sponsored by The University of Texas M. D. Roy S. Harry on October 30, 2001. Foundation (AVMF) Board of Directors at the Anderson Cancer Center in Houston. The AVMA Annual Convention in July 2001. To award recognizes young researchers who have 1941 advance the care and value of animals in made outstanding contributions to biomedical Bertrand B. Dionne on October 11, 2001. society, the AVMF distributes nearly $1 million sciences in the United States. Dr. Thomson was annually in support of student financial aid, honored for his pioneering work in the isola- 1946 scholarships, disaster relief, animal studies and tion and culture of nonhuman primate and Marvin Alexander on July 24, 2001. other initiatives. Dr. Bryant is an associate human embryonic stem cells—undifferentiated veterinarian at the Wilmington Animal Hospi- cells that have the ability to become any of the 1950 tal in Wilmington, Del. She also serves as staff cells that make up the tissues of the body. Edward D. Bubser on June 16, 2001. veterinarian and veterinary advisor to Eden 1990 Alternative, a program that incorporates pets, 1951 children, and plants into nursing home During the PVMA’s Annual Meeting in William V.Gallery on October 8, 2001. facilities. August 2001, Michael R. Moyer was elected Vice-President. He owns Bridgewater Veteri- 1997 1952 nary Hospital, a companion animal practice, in Edward P.Newman in October 2000. Jennifer Chaitman has become board-certi- Cornwells Heights, Pa. fied in Internal Medicine-Small Animal by the American College of Veterinary Internal Medi- cine. Dr. Chaitman practices at Veterinary Share news with your classmates Internal Medicine and Allergy Specialists in 2002 about a new position or accomplishment, New York City. wedding or birth announcement, by send- ing your class note today! We accept pic- 1998 Penn Annual Heather Peikes has become board-certified tures, too, featuring alumni gatherings, by the American College of Veterinary Derma- whether it’s from a wedding or mini- Conference tology. Dr. Peikes practices at Veterinary Inter- reunion. Be sure to identify everyone in the nal Medicine and Allergy Specialists in New The 102nd annual continuing picture. Pictures will be returned only upon York Cit y. education conference for request. Send all your submissions to: veterinarians and veterinary Joshua E. Liss Births technicians will be held on Director of Alumni Relations January 30 and 31 in and Annual Giving 1994 Philadelphia. University of Pennsylvania Elizabeth Boucher Miquel, a daughter, School of Veterinary Medicine Lucienne, on July 26, 2001. Visit the web site and print the 3800 Spruce Street conference brochure: Philadelphia, PA 19104-6047 1999 E-mail July 19, 2001.

BELLWETHER 51 19 V.M.D.NotesV.M.D. NOTES V.M.D. V.M.D.Notes NOTES V.M.D. V.M.D.Notes NOTES V.M.D. NOTES V.M.D.Notes V.M.D. NOTES V.M.D.Notes V.M.D. NOTES 2001 Alumni Award of Merit Nominations Sought Nominations are being sought for three which foster the advancement of the profes- Alumni Award of Merit recipients, please visit recipients of the 2002 Alumni Award of sion and the School’s good name. . nary Medical Alumni Society (VMAS) Annu- the classes that end in “2” or “7,” and who will To make a nomination, please send a letter al Meeting during Alumni Weekend 2002 on be celebrating a five year reunion during explaining your reasons to: May 11. The VMAS honors alumni who have Alumni Weekend 2002. Members of the Joshua E. Liss made outstanding contributions to their pro- VMAS Executive Board will select the recipi- Director of Alumni Relations and fession and the School with the Alumni ents from the pool of nominees. Nominations Annual Giving Award of Merit. The award is given annually are due no later than January 25, 2002. University of Pennsylvania to recognize distinguished graduates for their For more information or if you have any School of Veterinary Medicine contributions that advance knowledge in bio- questions, please contact Joshua E. Liss, 3800 Spruce Street medicine, promote the welfare of animals Director of Alumni Relations and Annual Philadelphia, PA 19104-6047 through public education of animal owners, Giving, at (215) 898-1481 or via e-mail at and benefit society through civic activities . For a list of previous

Alumni Connections To find a former classmate and to sign-up for To request a transcript and/or Alumni Relations and Annual Giving Staff: a permanent e-mail forwarding service: proof of graduation: Joshua E. Liss Join the University of Pennsylvania For information on requesting a tran- Director of Alumni Relations and Annual Alumni On-Line Community for free at script, visit the Office of the University Regis- Giving . trar’s web site at (215) 898-1481 After you register, you can search the On-Line or Fax (215) 573-3544 Directory, which is a great resource for per- call (215) 898-7511. For information on E-mail sonal and professional networking and an requesting a certification of graduation, which easy way to keep up-to-date on fellow alumni. does not require a transcript, contact the Elizabeth McNamara You can also sign-up for a permanent e-mail School’s Office of Student & Curricular Annual Giving Coordinator forwarding service, which will forward mes- Affairs at (215) 898-3525 or via e-mail at (215) 898-1480 sages received at your permanent Penn . Fax (215) 573-3544 address to the e-mail address of your choice. E-mail To obtain a Penn Alumni Card: To update your alumni record: The Penn Alumni Card offers a myriad of Please address any correspondence to: You can update your record via the Uni- benefits, including access to the Penn Office of Development and Alumni Relations versity of Pennsylvania Alumni On-Line Libraries. The charge for the card, which is University of Pennsylvania Community On-Line Directory. You may also valid for 10 years, is only $20. Alumni Cards School of Veterinary Medicine contact Elizabeth McNamara at (215) 898- are issued at the PennCard Center, which is 3800 Spruce Street 1481 or via e-mail at located in the Franklin Building at 3451 Wal- Philadelphia, PA 19104-6047 . nut Street. In order to receive the card, alumni are asked to show a form of photo identifica- To make a gift or for information on support- tion (a valid driver’s license, passport, etc.) ing the School of Veterinary Medicine: and complete an Alumni Card Request Form. Make a gift with your credit card through It then takes only a few minutes to take a a secure online transaction at photo of the alumnus/alumna and for them . For information on to receive their Alumni Card. As an added supporting the School, visit the Alumni & convenience, alumni can also obtain an Alum- Friends web site at ni Card by mail. For more information or to or contact download a request form, visit the “Obtaining Joshua E. Liss at (215) 898-1481 or via e-mail a PennCard” web page at at . .

20 BELLWETHER 51 V.M.D.NotesV.M.D. NOTES V.M.D. V.M.D.Notes NOTES V.M.D. V.M.D.Notes NOTES V.M.D. NOTES V.M.D.Notes V.M.D. NOTES V.M.D.Notes V.M.D. NOTES Alumni Weekend 2002 Tentative Schedule of Events Friday,May 10–Saturday,May 11 Philadelphia Photography by Jon Adams/hi5photos by Photography Friday,May 10—Begin Alumni Weekend 2002 by going back into the classroom! 2:00-3:00 p.m. Alumni Weekend 2002 Classes Without Quizzes Presentation “My Pet Has Changed: Understanding Aging-Related Behavior Changes in Dogs and Cats” by Dr. Ilana R. Reisner, Assistant Professor of Behavioral Medicine and Director of the Behavior Clinic at the Veterinary Hospital of the University of Pennsylvania Houston Hall, Golkin Room, 3417 Spruce Street Learn how to deal with your aging pet from Dr. Ilana R. Reisner, a board-certified veterinary behav- iorist. With improved nutrition and medical care, the life expectancy of our pets has been rising. Hear about the current understanding of dementia in dogs and cats, and updates on the research and manage- ment of this common problem. Time will be reserved for questions and answers. Saturday,May 11—Make it a day on the School’s Philadelphia campus! 8:30-10:00 a.m. Continuing Education Course (E.R. Marookian, V.M.D., Auditorium, VHUP) Topic to be announced Make your hotel and 10:30 a.m.-12:00 p.m. Veterinary Medical Alumni Society Annual Meeting (Marookian Auditorium) travel plans early! See your Alumni Society at work, and watch the presentation of the 2002 Alumni Award of Merit to three graduates celebrating a For your convenience, class reunion in 2002 rooms have been 12:00-2:30 p.m. Alumni Day Picnic (Hamilton Village, across Spruce Street from the School) reserved throughout Enjoy a buffet-style luncheon with alumni, special activities will Philadelphia for alumni be available for children at Kid’s Corner attending Alumni 2:30-3:30 p.m. Parade of Classes (Locust Walk) Weekend 2002. To make Show your school spirit by participating in one of Penn’s your reservations, con- favorite traditions tact Fran A. Engelbach, 3:00-4:30 p.m. Tours of VHUP,Philadelphia Research Facilities CW’62, at Monarch 5:00-6:30 p.m. Dean’s Alumni Reception (University of Pennsylvania Museum of Travel Services, Inc., at Archaeology and Anthropology, 33rd & Spruce Streets) (215) 557-7177 or toll- 6:30 p.m. Alumni Dinner Honoring the 2002 Reunion Classes (years ending in “2” or “7,” free at (800) 458-7177. University Museum)

A brochure with registration information will be sent early in 2002. For more information on Alumni Weekend 2002, please contact Joshua E. Liss, Director of Alumni Relations and Annual Giving, at (215) 898-1481 or via e-mail at .

BELLWETHER 51 21 Expanded Services in Medical Genetics Dr. John Melniczek, V’92, post-doctoral fel- which seeks to identify patients that might have A call for low in medicial genetics, re-joined the clinical inherited metabolic disorders; the hematology staff of the Section of Medical Genetics and has laboratory that provides assistance in identify- NBC memories been assisting Drs. Urs Giger, Margret Casal ing blood compatibility products for patients New Bolton Center celebrates its 50th and Hamutal Mazrier in expanding the clinical through the blood bank, and in the identifica- birthday in 2002. and laboratory services offered to VHUP clini- tion of canine and feline blood disorders; the We are collecting stories and reminis- cians and referring veterinarians. cytogenetics laboratory that identifies patients cences about New Bolton Center. Along with a strong clinical and research who have disorders of sexual development; and Share your New Bolton Center mem- background in the field of medical genetics, he the newest laboratory, the Josephine Deubler ories with us. We would like to hear brings with him a great interest in identifying Genetic Disease Testing Laboratory, which has from those of you who were at New and correcting, where possible, canine and been identifying carriers and affected animals Bolton in the last five decades. feline reproductive problems, and in assisting for a variety of breed-specific genetic diseases Please send your “memories” to Jane owners in pediatric care and genetic counsel- in cats and dogs. Simone via email ing. Artificial insemination will now be avail- To inquire about referrals for patients with or via mail able in canine infertility cases that the primary reproductive, pediatric, or genetic problems, or to her at New Bolton Center, 382 West clinician believes could benefit from such a to ask questions about the services provided by Street Road, Kennett Square, PA 19342- procedure. the laboratories, Dr. Melniczek and the rest of 1692 Dr. Melniczek will also be available to the Section of Medical Genetics’ staff can be answer questions regarding the Section’s four reached at 215-898-4680 or at laboratories: the metabolic screening laboratory http://www.vet.upenn.edu/penngen. Join the Pet Memorial Program stablished in 1982, the Pet Memorial responses from their clients upon being streamline the administration of the Program. Program has grown from a handful of informed that a gift to VHUP has been made For each tax-deductible contribution of Eveterinarians to a large group of practi- in memory of their pet. If you do not already $100 to the School, participating veterinarians tioners across the country who make gifts in participate, you are encouraged to do so. will receive 10 note cards to send to their memory of clients’ pets. The funds raised The Program has been recently reviewed to clients. Not only will this support enhance their enhance teaching and service, which in turn make it more efficient for both the School and client relations’ efforts, it will help to maintain helps the Veterinary Hospital of the University the participating veterinarians. Beginning on VHUP’s standard of excellence. of Pennsylvania (VHUP) provide the best vet- January 1, 2002, notification cards will be sent For more information or for card order erinary care for its companion animal patients. by veterinarians instead of the School. This forms, please contact Elizabeth McNamara, Those veterinarians who participate in the decision was made in consultation with several Annual Giving Coordinator, at (215) 898-1480 Program agree that it is an excellent client rela- of the participating veterinarians, and will or via e-mail at . tions tool, and they have received wonderful

A contribution to the University of Pennsylvania School of Veterinary Medicine has been made by

in memory of

This donation supports the Veterinary Hospital of the University of Pennsylvania, a leader in the development of new treatments and technologies to improve the health and care of companion animals. One of the largest and most advanced companion animal teaching hospitals in the world, the Veterinary Hospital of the University of Pennsylvania (VHUP) sees more than 26,000 patient visits a year, including more than 9,000 through the Emergency Service. As part of the University of Pennsylvania School of Veterinary Medicine, VHUP is at the forefront of training students and veterinarians in the diagnosis and treatment of animal diseases. For more infor- mation on VHUP, visit the School of Veterinary Medicine’s web site at .

22 BELLWETHER 51 Blood Bank Helps Bleeding Puppy inni, a 10-month-old Chihuahua, was and platelets. Each referred for treatment to the pediatric cellular compo- Band genetic service at VHUP by Trooper nent has its own Veterinary Hospital in Norristown, Pa. The dog function within had developed a large, painful hematoma over the body: red his back caused by hemophilia, a common, blood cells are severe, hereditary bleeding disorder that affects responsible for males. Transfusion of clotting factors can stop carrying oxygen the bleeding and be life-saving. from the lungs to The Penn Animal Blood Bank (PABB) col- all vital tissues lects and prepares thousands of units of blood and organs, white products each year for VHUP’s patients. The blood cells help blood and blood products are typed and care- the body fight fully screened for known and emerging infec- infection, and tious diseases to prevent transmission of such platelets are a nec- diseases to patients. essary part of the Blood consists of two portions: a liquid body’s clotting portion, called plasma, and a cellular portion, mechanism. Plas- consisting of red blood cells, white blood cells ma acts as a carri- Binni with a huge hematoma. er system for these cells, as well as many impor- tant proteins, vitamins and nutrients. When a unit of blood is collected from a Giving and Receiving donor, all of these components are represented, and the blood is referred to as whole blood. In We are pleased to offer several philanthropic plans most cases, a seriously ill animal does not need Would you that let you do just that. whole blood but just one or two components. consider a Therefore, the PABB nursing staff, after return- Charitable remainder trusts offer outstanding ing from volunteer canine blood drives in the charitable planning flexibility, with rates starting at 5%. Delaware Valley, separates the blood into its gift of components with the help of technologically $10,000 Charitable gift annuities offer guaranteed fixed advanced equipment. “One unit of collected income for life at rates of 6% to 9.5% (may be higher blood benefits more than one patient,” says or more if if you defer income). Donna Oakley, director of PABB and VHUP you could nursing. “A patient can be treated specifically All of Penn’s Life Income Gift Plans offer you: with only the component needed. This reduces retain an the risk of adverse reactions.” Some of the income • Current income tax deduction blood components can be stored for a month • Significant capital gains tax savings and others for one year and are immediately interest in • Guaranteed income for life or a term of years available in an emergency. Because of the large assets that • Option to defer income for higher income and deduction size difference between dog breeds, blood units you give • No management fees for gift annuities, low fees for trusts of different sizes are needed. “Although we are • Enduring support for the School of Veterinary Medicine, applying blood banking standards from human away? VHUP, or New Bolton Center medicine, we had to develop comparable methods for our small patients, such as toy For more information or a personalized illustration with no obligation, breeds and cats,” says Wendy Hatchett, another PABB nurse. call Penn’s Office of Gift Planning at 800-223-8236 or email Binni needed to be transfused with a small . Be sure to mention the Bellwether. unit of plasma twice daily for a couple of days to achieve resolution of the hematoma and fur- Life income gifts may be funded with cash, marketable securities, or other assets in some cases. Income may ther healing. Because hemophilia is a heredi- be current or deferred. Rates and deductions vary with age and number of income beneficiaries and the tary disorder, it is likely that Binni will have timing of the gift. Penn gift annuities are not available in all states. Minimum gift amount is $10,000 for recurrences. Specific small units have been pre- charitable gift annuities and $100,000 for charitable remainder trusts. Thank you. pared and are readily available for his treat- ment in the future.

BELLWETHER 51 23 Animal Crackers BOOK REVIEW Walking Horses, Standardbreds, Appaloosas, Factual information concerning various Arabians, Morgan Horses and Saddlebreds. forms of biological and chemical agents and PET CARE IN THE NEW CENTURY: Cutting The average price of Thoroughbred year- the mail may be found at: Edge Medicine for Dogs and Cats by Amy Shojai. lings sold at auction in 2000 was $54,506. Center for Disease Control — New American Library (Penguin Putnam Inc., Kentucky is the foundation of the http://www.chc.gov 375 Hudson St., New York, NY 10014.) Thoroughbred breeding industry with 416 stal- United States Postal Service — Paperback, $14.00. lions and 20,616 mares bred in 2000. http://www.usps.gov Here is an up-to-date reference book cover- The average horse eats 11,000 pounds of Pennsylvania Department of Health — ing modern veterinary care. More than a hun- hay, grass and grain each year. On average, a http://www.health.state.pa.us dred veterinarians, among them quite a few horse consumes two to three ounces of salt from Penn, (listed in an appendix) explain daily. During moderate work, it can lose 1.75 to many health and behavior conditions, arranged 2.2 ounces of salt in his sweat and 1.25 ounces alphabetically. There are notes on contact lens- in urine. A horse will consume as much sodi- es as a diagnostic aid as well as protective glass- um as it needs when offered salt free choice. es. Tests for hearing loss are discussed and Bellwether University of Pennsylvania School of Veterinary Medicine hearing aids that are available. Pacemakers are ANTHRAX used for some heart problems in dogs. Kidney Editor transplants are used for cats. The topics include Anthrax is a disease which occurs in almost Helma Weeks aggression, cancer, cognitive disorders, obesity, all warm-blooded animals and humans. The Photographers pain, parasites and vaccinations. “Modern Mir- disease is also called Charbon, Milzbrand and Jon Adams acles” describe results of innovative treatments. Splenic Fever. The human form is known as Addison Geary The appendix lists veterinary colleges in the woolsorters’s disease. It occurs worldwide. In Doug Thayer United States and their websites. A specialist the United States there are recognized areas of Writers infection but it has not been seen in Pennsylva- Stephen Bradt has completed additional training and is a Dr. Josephine Deubler “Diplomate” of a veterinary specialty college. nia for decades. Joan Capuzzi Giresi, V.M.D. The appendix gives contact information. The cause is Bacillus anthracis, a spore- Patrick A. Mahaney, V.M.D. Among the specialties are internal medicine, forming bacterium. The spores may remain Alumni Relations Liaison dermatology, ophthalmology, surgery, radiolo- viable for decades. Infection of herbivores Joshua E. Liss gy, nutrition and behavior. Most have websites occurs when they graze in areas where spores New Bolton Center Liaison listing members. in the soil are activated by change in conditions Jeanie Robinson-Pownall such as flood or drought, especially if the tem- The human-animal bond brings up ethical We’d like to hear your praise, criticisms, or com- questions, which are thoughtfully covered. New perature is over 60 degrees. Other species are ments. Please address your correspondence to: infected when they eat meat of animals dead of procedures may receive much publicity, but Helma Weeks their effectiveness has not been proven. Pet anthrax, get contamination of skin cuts or University of Pennsylvania insurance now is available to help cover the inhale large numbers of spores. The generalized School of Veterinary Medicine cost. It may cover experimental treatments, but form is characterized by rapid onset and may 3800 Spruce Street be rapidly fatal. Localized infections usually Philadelphia, PA 19104-6010 not pre-existing or inherited conditions. Some (215) 898-1475 owners never question the cost of saving a pet’s respond to treatment. Intestinal anthrax is [email protected] life while others consider spending a “fortune” acquired by eating raw or undercooked infect- None of these articles are to be reproduced in a poor ethical choice. Is there an answer? ed meat. any form without the permission of the editor of The difficult subject of genetics is briefly The first vaccine for anthrax was made by Bellwether. covered. Molecular medicine looks for causes Pasteur in 1879 and annual vaccination of © Copyright 2001 by the Trustees of the University of Pennsylvania. of disease in the genes. Research has identified grazing animals can control the disease in the genes involved in many canine and feline endemic areas. Ciprofloxacin is the antibiotic The University of Pennsylvania values diversity and seeks talented students, faculty and staff from diverse diseases and tests can be used to identify sus- of choice for treatment, although the organism backgrounds. The University of Pennsylvania does is sensitive to a large number of antimicrobials. not discriminate on the basis of race, sex, sexual ori- pected carriers. entation, religion, color, national or ethnic origin, This book covers many advances in veteri- It is important that regulatory officials be noti- age, disability, or status as a Vietnam Era Veteran or fied if the disease occurs or is suspected so disabled veteran in the administration of education- nary medicine and shows you how to take al policies, programs or activities; admissions poli- advantage of them. It’s a worthwhile addition appropriate control measures can be taken. cies; scholarship and loan awards; athletic, or other University administered programs or employment. to the library of dog and cat owners. Anthrax spores manufactured for criminal Questions or complaints regarding this policy should purposes can have the appearance of a white be directed to: Executive Director, Office of Affirma- tive Action and Equal Opportunity Programs, 3600 NOTES ON HORSES powder. If there are suspicious circumstances, Chestnut Street, Sansom Place East, Suite 228, local law enforcement authorities should be Philadelphia, PA 19104-6106 or (215) 898-6993 Paint and Quarter Horses lead in registra- (Voice) or (215) 898-7803 (TDD). notified. tions, followed by Thoroughbreds, Tennessee

24 BELLWETHER 51 American Gold Cup 2001 he American Gold Cup was held September 13 to 16 at and Christine Connelly enjoyed their assignment and Tthe Devon Show Grounds. Events of September 11 cast awarded numerous prizes. Many children came with draw- a big shadow. Everyone wore red-white-and-blue ribbons ings and paintings and participated in the art show. Sunday and collections were taken for victims and survivors. Friday featured the grand finale, the competition for the American afternoon and evening activities were cancelled in defer- Gold Cup. It was won by Kimberley Frey on Berberac. ence to the national day of mourning. The School’s booth was easily identifiable by the lifesize Saturday featured added classes in the Dixon Oval. The wooden Harnessmaker’s horse that the New Bolton Center day was packed with activities. The celebrity dog show crew had suspended from a tree. drew a large entry and a large crowd. Judges Barry Stupine

BELLWETHER 51 25 Special Gifts to the School The following gifts were made to Friends of New Bolton Center in The following have made gifts to the Veterinary Hospital of the Kathryn Staci in memory of “SONJA” memory of a special animal: University of Pennsylvania in memory of a special pet: Ms. Lisa Stanwyck in memory of “TAD” The Davis/Hirsch Family in memory of “CAESAR” John H. Abrams & Judith S. Everitt in memory of Mr. Michael Telenda in memory of “YUKON” Dr. Carol Anne Dolinskas in memory of “RULY” “HENRY” Mrs. Helma N. Weeks in memory of “ROMEO” Ms. Elizabeth W. Glascock in memory of “LANCELOT” Ziva Simon Alon in memory of “ELZA” Mr. and Mrs. Richard Walters in memory of “JESSIE” Hilltop Farm and Mrs. Jane MacElree in memory of Amy L. Anderson in memory of “RICO” Ms. Mary Kay Washo in memory of “BRIGETTE RED” “ROYAL RENDITION” Ms. Robin Bausback in memory of “MOLSON GOLDEN” Ms. Kathleen Wert in memory of “FRITZ”,“NIKKI” and Mr. and Mrs. John P. McFadden, Jr. in memory of Mr. Stephen F. Bezuk in memory of “MISTY” and “LUCKY” “MOSELLE” “MISTER BAD” Ms. Linda Weyler in memory of “BLACKIE” Ms. Allison Schomber in memory of “VEOLETTE” Mrs. Jacqueline Bofinger in memory of “CASEY” Ms. Stephanie Yarbough in memory of “SASHA”and “DIRTY FACE” The following gifts were made to Friends of New Bolton Center in Mr. and Mrs. John Capuzzi in memory of “MOLLY” honor of those listed: Mr. and Mrs. Chadwick in memory of “RASCAL” The following have made gifts to the Veterinary Hospital of the Mr. and Mrs. Eugenio Chinigo in memory of “BRANDY” University of Pennsylvania in memory of Terry Woods: Ms. Beverly Barnes in honor of Sheba and Ally Barnes & “BIANCA” Action Duplication, Inc. Mr. and Mrs. John S. Craig in honor of Dr. Dan Morris Mr. Oliver B. Cospelich in memory of “PHAROAH” & Mr. and Mrs. Wayne A. Althouse Kenneth K. Sadanaga, V.M.D. in honor of Dr. Jill Beech’s “BART” Martha L. Ames appointment as the Georgia E. and Philip B. Hofmann Ms. Nancy Dagle in memory of “SEDGEWICK” Philomena T. Andreoni Professor in Equine Medicine & Reproduction Ms. Teresa A. Demusis in memory of “RASCAL” Christine Augustine Ms. Barbara Silverstein in honor of Mr. Tom Taylor Ms. Judith DeStefano in memory of “CLEOPATRA” Mrs. Joan T. Buck Ms. Sally Evans in memory of “INKY” The following gifts were made to Friends of New Bolton Center in Mr. and Mrs. Ronald O. Buck Mr. and Mrs. Chris Fahey in memory of “PEPPER” and memory of Mr.James Armstrong: Sheila M. Bury “CINNAMON” Mr. and Mrs. Vladimir Borodavchuk Michael W. Carr Ms. Marjorie Fein-Deutsch in memory of “JESSICA” Ms. Edna S. Moore Pamela Davis Ms. Yvonne Ehrhart in memory of “DIXIE” Ms. Helen K. Pople Mr. and Mrs. Del Viscio Mr. and Mrs. Mulford E. Emmel in memory of Mr. and Mrs. Pete Tester Mr. and Mrs. Jeffrey J. Destefano “ABERCROMBIE” Joanne DiCampli The following gifts were made to Friends of New Bolton Center in Mr. Richard Feldman in memory of “NIGEL” Lynn M. Dignazio memory of Ms.Diana Muss: Ms. V. Susan Fisher in memory of “SOPHIE” Denise M. Durbano Mr. and Mrs. Lewis I. Gantman Mr. and Mrs. Jeffrey Gelfand in memory of “KOTI” Henry J. Frentzen Mr. Louis I. Gantman Ms. Susan Gibson in memory of “MAGGIE” Mr. and Mrs. Kenneth Grant Mr. Art Powell Mr. and Mrs. Scott Green in memory of “COCO” Mr. and Mrs. James Klecko Mr. Harold Schaeffer Ms. Eileen Haley in memory of “SENNA” Carol Ann Kruklis Mr. Wayne Snyder Ms. Meredith Heckler in memory of “MOLLY” Judith M. Lowenstein The employees of the Kravco Company Ms. Carolyn Heiser-Wood in memory of “MAXWELL Mr. and Mrs. Walter Mackin OLIVER” Mr. and Mrs. David Madden Mr. William Hoffman in memory of “CHACO” Mr. and Mrs. Matthew C. Maturani Ms. Lily Hoge in memory of “PETIE” and “EMMA” Mr. and Mrs. Joseph Mundy, Sr. Ms. Joan Kaufman in memory of “PRINCE” Mr. and Mrs. James Nasella Mr. and Mrs. Stephen Kazakoff in memory of “NUGGET” Kathleen E. Parente Trivial Pursuit Ms. Joan Kistler in memory of “MAXINE” Pamela Jean Parker Ms. Joan Kistler in memory of “PRINCE” & “SPARKY” If you play Trivial Pursuit Genus 5 you Gale Ranalli Mr. John Kurten in memory of “LUCKY” Mr. and Mrs. Samuel C. Schmeltzer may draw a card that asks “What major Ms. Elizabeth Langan in memory of “CEILI” Lori Solomon Eastern city was the first to boast a blood- Ms. Bernadine A. Lennon in memory of ‘SHADOW” State Farm Mutual Automobile Insurance Company Ms. Wendy Mace in memory of “SPARKY” mobile for dogs, in 1991?” State Farm Insurance Companies Ms. Wendy Margolis in memory of “SOPHIE” Tanya Lee Tumas The answer is: Philadelphia (at VHUP, Tomi J. McCann, M.D. in memory of “BUDDY “ and Robert Woods “PEDO” of course!) Carolyn Zimmerman Ms. Betty Louise McCurdy in memory of “HERKIMER” Nancy A. McDermott in memory of “MUFFY” The following have made gifts to the Veterinary Hospital of the Mr. and Mrs. James A. McMillan in memory of “ROCKY” University of Pennsylvania in memory of Jack Glover: Mr. David J. Mealmaker in memory of “NUNZIO” Mr. and Mrs. Robert P. Corlies Mr. Jerry Michaels in memory of “GOLDY” Clifford P. Crowers Mrs. Judith Morlacci in memory of “NIKKI” Mr. and Mrs. Richard Lippin Ms. Sonya Peterson in memory of “PJ” Doris Marie Londer Ms. Marie Pinizzotto in memory of “CHRISSY” Mrs. Zoreslava L. Mysko Mr. and Mrs. James Olive in memory of “PEBBLES”, Helen Mae Mullen “REINA”& “BONNIE” Mr. and Mrs. Owen Regan Ms. Mary Rice in memory of “SUGAR PIE” Mr. and Mrs. Harry B. Reiff Mr. and Mrs. Carl Rulis in memory of “BRANDY” The following have made gifts to the Veterinary Hospital at the Mr. and Mrs. Gregg Runyen in memory of “MEGGIE” University of Pennsylvania in memory of those listed: Ms. Susan A. Schmidt in memory of “FRITO BANDITO” Mr. and Mrs. Paul J. Schoff in memory of “PIPER” Linda Bergh in memory of E. Joanne Bristol Ronni and Lester Schwartz in memory of “TANYA” Mr. and Mrs. Bernard Brewstein in memory of Sara Jane Ms. Randi S. Semanoff in memory of “CHLOE” Dickstein Mr. and Mrs. Paul Seymour in memory of “COCO” Frances M. Iadevaio in memory of Joseph P. Sanfilippo Mr. Joseph Sgro in memory of “MOLLY” Mr. and Mrs. Arthur Kast, Jr. in memory of Susie Kast Mr. Gene W. Sharpless in memory of “SANDY” Ms. Diane Mengel in memory of Dr. Robert B. Weber Mr. and Mrs. Rocco Siravo in memory of “NOEL” Mr. and Mrs. David A. Miller in memory of John Johnson Ms. Diane Sjolander in memory of “MOLLY” and “SAGE” Ms. Maryjeannette J. Monihan in memory of Dr. W.M. Mr. and Mrs. Charles W. Smith in memory of Gallery “SAMANTHA” Kathryn Staci in memory of “BANDIT”

26 BELLWETHER 51 The following have made gifts to the Veterinary Hospital of the Mr. and Mrs. Andrew R. Budman in honor of “COOKIE” Mr. and Mrs. Charles Thompson in memory of Irvin University of Pennsylvania in honor of a special pet: The following have made gifts to the Special Species Medicine Hymerling Ms. Tammy James in honor of “RIDLEY” Clinic in honor of those listed: The following have contributed gifts to Veterinary Student Ms. Sheree Mazzella in honor of “MAXWELL” Mr. and Mrs. Andrew R. Budman in honor of Dr. Karen Scholarship in honor of those listed: Mr. and Mrs. Don O’Connor in honor of “MISSY” and Rosenthal Joseph F. DiMauro, V.M.D. in honor of Loren Evans, “RUSTY” D.V.M. Mr. and Mrs. Rocco Siravo in memory of “NOEL” The following have made gifts to the Josephine Deubler Student Scholarship in honor of those listed: Horsham Veterinary Hospital, P.C. in honor of Loren The following have made gifts to the Veterinary Hospital of the Evans, D.V.M. University of Pennsylvania in honor of those listed: Mr. Dale C. Deubler in honor of M. Josephine Deubler, Michael S. Miller, V.M.D. in honor of Dr. David K. V.M.D. Mr. and Mrs. Nicholas Christopher in honor of Drs. Ann Detweiler Wayne Lucas and Diane DeLorenzo’s work at The following have made gifts to the Josephine Deubler Genetic Dr. Barbara Ruch in honor of Dr. Suzanne R. Jenkins Washington Square Animal Hospital Disease Testing Laboratory in memory of a special pet: The following have contributed gifts to Veterinary Student Ms. Helen Davenport in honor of Dr. Christopher Donner Ms. Phyllis N. Sewall in memory of “LACEY” Scholarship in memory of a special pet: Mr. and Mrs. C.D. Deringer in honor of the 30th Mr. and Mrs. Nicholas J. Masciulli in memory of “SPOTS” Anniversary of Barbara and Larry Magic The following have made gifts supporting Soft Coated Wheaten Ms. Marilyn S. Wiesen in memory of “POKEY” Ms. Tammy James in honor of Dr. Chick Weisse Terrier Research in memory of a special pet: Mr. and Mrs. Arthur Kast, Jr. in honor of Dr. Prudence The following have contributed gifts to the E.R.Marookian Neath Mr. Richard Tomlinson in memory of “GINGER” Research Scholarship Fund in honor of Dr.Edgar R.Marookian: Mr. James Koch and Ms. Karen Bossert in honor of Dr. The following have made gifts supporting Diabetes Research in Mr. and Mrs. Edward Elmasian Chick Weisse and Dr. Tona Melgarejo memory of a special pet: Mr. and Mrs. Paul Jaffarian Ms. Margie Levi in honor of Nathan’s birth Ms. Christine Lally in memory of “LADY” Robin M. Mazin, V.M.D. in honor of Dr. Cynthia Otto’s contribution to the WTC search and rescue mission The following have made gifts supporting Oncology Research in Ms. Carolyn B. Pope in honor of Dr. Christiansen for his memory of a special pet: work with Julio Pope Ms. Catherine Ciric in memory of “BU” Recent Gifts of Note Mrs. Letitia O. Principato in honor of Raymond A. Mr. and Mrs. Steven Conant in memory of “HANNAH” Harding Mr. and Mrs. Raymond J. Higgins in memory of The School received $60,000 from the Mr. and Mrs. Robert Rapiejko in honor of Dr. Tracy “STEPHANIE” estate of Jean Shepherd to establish a schol- Springer Ms. Carolyn B. Pope in memory of “ROMEO” arship for women in the name of Leigh Ms. Linda Weyler in honor of Dr. Lilian Duda and Dr. Amy The following have made gifts supporting Oncology Research in Kapatkin Brown Shepherd. Jean Shepherd died in honor of those listed: October 1999 at the age of 78, he was a resi- The following have made gifts supporting Epilepsy Research in Ms. Carolyn B. Pope in honor of Dr. Lisa Barber memory of a special pet: dent of Sanibel Island, Fl. The following have contributed gifts to the Dean’s Fund in honor Mr. and Mrs. Barry Miller in memory of “FLUFFY” of those listed: Mary R. Romig-DeYoung, through her The follow have made gifts to the Clinical Studies Research Mrs. Carolyn R. Cotter in honor of Dr. Lesley King estate, provided $250,000 for an endow- Development Fund in memory of Juno: Mrs. James S. Vandermade in honor of Dr. David Detweiler ment fund to support animal care and Ms. Patricia diPietrae The following have contributed gifts to the Dean’s Fund in Mrs. Patricia Hall treatment at VHUP. Mrs. Romig-DeYoung, memory of those listed: Mrs. Jennifer Liss who died in October 2000, was a long-time Mr. Joshua Liss Stephen R. Levan, V.M.D. in memory of Russell S. Detwiler, supporter of the University. Ms. Marie McEntee V.M.D. Ms. Catherine McNamara Ms. Kathleen McSherry in memory of Mary and Joseph Thoroughbred Charities of America Ms. Susan Mullins McSherry contributed $50,000 to New Bolton Center Karen Seamans in memory of Mr. Earl Holton Ms. Jeanie Robinson-Pownall for equipment for the Scott Equine Sports Mr. Timothy Rupe The following have contributed gifts to the Dean’s Fund in Mrs. Jane Simone memory of a special pet: Medicine Building. This organization is a Mr. Mark Stuart Betsy Dayrell-Hart, V.M.D. in memory of “TOSCA” charity created by Herb and Ellen Moelis, Ms. Ellen Tarasca Mr. and Mrs. Paul Seserko in memory of “HOLMHAVEN long-time supporters of the School. Herb is Ms. Helma Weeks JASON OF SEALOCH” a member of the School's Board of Ms. Andrea Withers Ms. Margaret Yeaw in memory of “BIG KITTY” Overseers. The follow have made gifts to the Clinical Studies Research The following have contributed gifts to the Clinical Studies Development Fund in memory of Katie: Critical Care Fund in honor of those listed: General Econopak, specialists in surgical Mrs. Patricia Hall Mrs. Roberta M. Webb in honor of Dr. Bisque Jackson apparel and products, made a donation of Dr. David Holt Mrs. Jennifer Liss The following have contributed gifts to the Chinchilla Research $30,000 to the School. General Econopak Mr. Joshua Liss Fund in memory of those listed: has had a long-standing relationship with Ms. Marie McEntee Estate of Helen S. White in memory of Helen White the School and its hospitals. Half of the Ms. Elizabeth McNamara The following have contributed gifts to Veterinary Student Mrs. Amy-Lynn Parkman funds will be used at New Bolton for the Scholarship in memory of those listed: Ms. Jeanie Robinson-Pownall purchase of equipment. The remainder will Richard G. Ainley, V.M.D. in memory of Robert Ainley Mr. Timothy Rupe be used at VHUP for installation of exter- Mrs. Phyllis Sewall Vanderhoof, V.M.D. Mrs. Jane Simone Cathy A. Ball, V.M.D. in memory of Sister Catherine nal nitrogen lines to power special equip- Mr. Mark Stuart Henrietta ment in the surgery suites. A bequest of William Deeds Donovan, V.M.D. in memory of Dr. Sam Ms. Ellen Tarasca $10,000 from the estate of Lynne Wick- Ms. Andrea Withers Scheidy Barbara L. Henderson, V.M.D. in memory of Thomas A. enden will also be applied to this VHUP The following have made gifts to the Special Species Medicine Henderson project. Clinic in honor of a special pet: Dr. Christopher Morris in memory of Dr. Robert B. Weber Mrs. Dana Goodyear in honor of “FOUR STEP ROSE” Lawrence W. Samples, V.M.D. memory Dr. Robert B. Weber

BELLWETHER 51 27 BELLWETHER 51 FALL/WINTER 2001

Upcoming Events January 2002 March 2002 May 2002 5-10 13 8 Pennsylvania Farm Show 2002 2:00-4:00 p.m. 2:00-4:00 p.m. Farm Show Complex Veterinary Medical Alumni Society Executive Board Meeting Veterinary Medical Alumni Society Executive Board Meeting Harrisburg, PA Alumni Hall Veterinary Hospital of the University of Pennsylvania Visit the School of Veterinary Medicine’s booth at New Bolton Center the largest indoor agricultural event in America. For Kennett Square, PA 10-11 information, visit . Annual Feline Symposium for Owners and Breeders For information, visit . 13 Veterinary Hospital of the University of Pennsylvania 8:00-10:00 p.m. For information, call Dr. Josephine Deubler at 10 Alumni Reception (215) 898-8862 or visit . Alumni Weekend 2002 Classes Without Quizzes Presentation Grand Caribbean Ballroom II “My Pet Has Changed:Understanding Aging-Related Caribe Royale Behavior Changes in Dogs and Cats” Orlando, FL by Dr. Ilana R. Reisner, Assistant Professor of Behavioral Medicine and Director of the Behavior 26 Clinic at the Veterinary Hospital of the University of Annual Canine Symposium for Owners and Breeders For updated Pennsylvania E.R. Marookian, V.M.D. Auditorium Houston Hall, Golkin Room Veterinary Hospital of the University of Pennsylvania event listings, 3417 Spruce Street For information, call Dr. Josephine Deubler at (215) 898-8862 or visit . Dr. Ilana R. Reisner, a board-certified veterinary behaviorist. With improved nutrition and medical 30-31 care, the life expectancy of our pets has been rising. 2002 Penn Annual Conference Alumni & Friends Hear about the current understanding of dementia Adam’s Mark Hotel in dogs and cats, and updates on the research and Philadelphia, PA management of this common problem. Time will For information, visit . 13 30 at School of Veterinary Medicine Class of 2002 2:00-4:00 p.m. http://alumni.vet.upenn.edu Commencement Veterinary Medical Alumni Society Executive Board Meeting at 2002 Penn Annual Conference

Visit the School’s web site at www.vet.upenn.edu

University of Pennsylvania Nonprofit Organization School of Veterinary Medicine U.S. Postage 3800 Spruce Street PAID Philadelphia, PA 19104-6008 Philadelphia, PA Permit No. 2563 Address service requested

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