Neurospine 2019;16(3):456-461. Neurospine https://doi.org/10.14245/ns.1938200.100 pISSN 2586-6583 eISSN 2586-6591 Review Article C1 Stenosis – An Easily Missed Cause Corresponding Author for Cervical Myelopathy Andrei Fernandes Joaquim 1 2 3 2 https://orcid.org/0000-0003-2645-0483 Andrei Fernandes Joaquim , Griffin Baum , Lee A. Tan , K. Daniel Riew 1Neurosurgery Division, Department of Neurology, State University of Campinas (UNICAMP), Campinas-SP, Neurosurgery Division, Department of Brazil Neurology, State University of Campinas 2Department of Orthopedic Surgery, Columbia University, New York, NY, USA 3 (UNICAMP), Campinas, Brazil Department of Neurosurgery, University of California San Francisco, San Francisco, CA, USA E-mail:
[email protected] Received: June 13, 2019 C1 stenosis is often an easily missed cause for cervical myelopathy. The vast majority of cer- Revised: July 16, 2019 vical myelopathy occurs in the subaxial cervical spine. The cervical canal is generally largest Accepted: July 17, 2019 at C1/2, explaining the relatively rare incidence of neurological deficits in patients with odon- toid fractures. However, some subjects have anatomical anomalies of the atlas, which may cause stenosis and result in clinical symptoms similar to subaxial cord compression. Isolat- ed pure atlas hypoplasia leading to stenosis is quite rare and may be associated with other This is an Open Access article distributed under anomalies, such as atlas clefts or transverse ligament calcification. It may also be more com- the terms of the Creative Commons Attribution monly associated with syndromic conditions such as Down or Turner syndrome. Although Non-Commercial License (http://creativecom- mons.org/licenses/by-nc/4.0/) which permits the diagnosis can be easily made with a cervical magnetic resonance imaging, the C3/2 spi- unrestricted non-commercial use, distribution, nolaminar test using a lateral cervical plain radiograph is a useful and sensitive tool for screen- and reproduction in any medium, provided the ing.