HLA Risk Alleles in Aromatic Antiepileptic Drug-Induced Maculopapular Exanthema
ORIGINAL RESEARCH published: 26 May 2021 doi: 10.3389/fphar.2021.671572 HLA Risk Alleles in Aromatic Antiepileptic Drug-Induced Maculopapular Exanthema Yi-Wu Shi 1, Jie Wang 1, Fu-Li Min 2, Wen-Jun Bian 1, Bi-Jun Mao 1, Yong Mao 3, Bing Qin 4, Bing-Mei Li 1, Yang-Mei Ou 5, Yun-Qi Hou 6, Xin Zou 7, Bao-Zhu Guan 1,NaHe1, Yong-Jun Chen 8, Xue-Lian Li 9, Juan Wang 10, Wei-Yi Deng 1, Han-Kui Liu 3, Nan-Xiang Shen 1, Xiao-Rong Liu 1, Yong-Hong Yi 1, Lie-Min Zhou 11, Dong Zhou 12, Patrick Kwan 13 and Wei-Ping Liao 1* 1Institute of Neuroscience and Department of Neurology of the Second Affiliated Hospital of Guangzhou Medical University; Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou, China, 2Department of Neurology, Guangzhou First People’s Hospital, Guangzhou, China, 3BGI-Shenzhen, Shenzhen, China, 4Epilepsy Center and Department of Neurosurgery, The First Affiliated Hospital, Jinan University, Guangzhou, China, 5Department of Neurology, Guangdong 999 Brain Hospital, Guangzhou, China, 6The First People’s Hospital of Shunde, Foshan, China, 7The Third People’s Hospital of Mianyang, Mianyang, China, 8Department of Neurology, Nanhua Hospital Affiliated to South China University, Hengyang, China, 9Department of Neurology, The Affiliated Yuebei People’s Hospital of Shantou University Medical Edited by: College, Shaoguan, China, 10The Affiliated Hospital of Xiangnan University, Chenzhou, China, 11Department of Neurology, The 12 Chonlaphat Sukasem, Seventh Affiliated Hospital, Sun Yat-Set University, Guangzhou, China, West China Hospital, Sichuan University, Chengdu, 13 Mahidol University, Thailand China, Department of Neuroscience, Central Clinical School, Monash University, Alfred Hospital, Melbourne, VIC, Australia Reviewed by: Dean Naisbitt, To characterize human leukocyte antigen (HLA) loci as risk factors in aromatic antiepileptic University of Liverpool, United Kingdom drug-induced maculopapular exanthema (AED-MPE).
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