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Download The WHAT ABOUT CONDOMS? CONFERENCE UPDATE: T HE CROI REPORT WHY I RIDE: Ou T AND OPEN IN THE RIDE FOR AIDS CHICAGO POSITIVELY AWARE THE HIV TREATMENT JOURNAL OF TEST POSITIVE AWARE NETWORK MAY+JUNE 2015 T HE BIGGES CHANGES IN 20 YEARS ARE COMING REIn THINK NG HIV NEW APPROACHES TO TREATMENT n CHASING THE CURE n 3D animation OF HIV Client Name: GSK/Triumeq Healthcare This advertisement prepared by: Product: Triumeq Havas Worldwide Job Number: 200 Hudson Street 65013 Filename 65013_58522_M02_DTR045R0_CouchSpread_ Last Modified 1-14-2015 12:41 PM User / PrevUs- Derrick.Edwin / Aileen.Boyce Client GSK Triumeq Art Director M. Culbreth Bleed 16.25” x 10.75” Path Premedia:Volumes:Premedia:Pre- CMYK press:65013_58522:Final:Pre- 0000065013_0000058522_M02_DTR045R0_FCAD – Positively Aware New York, New York 10013 Create 1-14-2015 10:42 AM Artist Kerry Trim 16” x 10.5” press:65013_58522_M02_DTR045R0_ CouchSpread_FCAD-for PREPRESS. Proof Caption: “I have the courage to start HIV…” (Man on Couch) 3 Traffic R. Rodriguez Saftey 15” x 10” indd Fonts Helvetica Neue LT Std (75 Bold, 77 Bold Condensed, 57 Condensed, 55 Roman, 47 Light Condensed, 67 Medium Condensed, 47 Light Condensed Oblique; OpenType), Minion Pro (Regular; OpenType), TT Slug Media: 4/C Magazine Spread + PBW +PBW + ½ PBW AD: M. Culbreth OTF (Regular; OpenType) PAR # DTR045R0 AE: M. Halle Art TRIU_58522_01_CeasarCouchAd_SW_V6_HR.tif (Premedia:Prepress:65013_58522:Original:1.14.15:0000065013_0000058522_M02_DTR045R0_CouchSpread_FCAD Folder:Links:TRIU_58522_01_CeasarCouch- Ad_SW_V6_HR.tif), ViiVHCcmyk.ai (Premedia:Prepress:65013_58522:Original:1.14.15:0000065013_0000058522_M02_DTR045R0_CouchSpread_FCAD Folder:Links:ViiVHCcmyk.ai), Triumeq_US_CMYK_Reg_NEW. Prod: I. Waugh ai (Premedia:Prepress:65013_58522:Original:1.14.15:0000065013_0000058522_M02_DTR045R0_CouchSpread_FCAD Folder:Links:Triumeq_US_CMYK_Reg_NEW.ai), TRIU_58522_02_ItsTimeLogo_SW_V1_130_ B: 16.25” x 10.75” T: 16” x 10.5” Bill Studio Labor OOP to: 0000065013 S: 15” x 10” Gutter Safety = 1” B:16.25” T:16” S:15” TRIUMEQ is a once-a-day pill used to treat HIV-1. TRIUMEQ should not be used by itself in some people. Take TRIUMEQ exactly as your healthcare provider tells you. Is it time for you? Ask your doctor. APPROVED USES TRIUMEQ is a prescription medicine used to treat Human Immunodefi ciency Virus-1 (HIV-1) infection in adults. HIV-1 is the virus that causes AIDS. It is not known if TRIUMEQ is safe or effective in children under the age of 18. TRIUMEQ is not for use by itself in people who have or have had resistance to abacavir, dolutegravir, or lamivudine. TRIUMEQ does not cure HIV-1 or AIDS. You must stay on continuous HIV-1 therapy to control HIV-1 infection and decrease HIV-related illness. IMPORTANT SAFETY INFORMATION yellow skin, or the white part of the eyes turns yellow; dark urine; What is the most important information I should know about light-colored stools; nausea; itching; or stomach-area pain. TRIUMEQ? • Worsening of hepatitis B virus in people who have HIV-1 infection. If you have HIV-1 and hepatitis B virus infections, your • Serious allergic reaction (hypersensitivity reaction). TRIUMEQ hepatitis virus infection may get worse if you stop taking TRIUMEQ. contains abacavir. Patients taking TRIUMEQ may have a serious Do not stop taking TRIUMEQ without fi rst talking to your healthcare allergic reaction to abacavir that can cause death. Your risk is provider, so he or she can monitor your health. much higher if you have a gene variation called HLA-B*5701. Your healthcare provider can determine with a blood test if you have • Resistant hepatitis B virus. If you have HIV-1 and hepatitis B, this gene variation. If you get symptoms from 2 or more of the the hepatitis B virus can change (mutate) during your treatment with following groups while taking TRIUMEQ, call your healthcare TRIUMEQ and become harder to treat (resistant). provider right away: 1. fever; 2. rash; 3. nausea, vomiting, • Use with interferon and ribavirin-based regimens. If you’re diarrhea, or stomach pain; 4. generally ill feeling, extreme taking TRIUMEQ and interferon, with or without ribavirin, tell your tiredness, or achiness; 5. shortness of breath, cough, or sore healthcare provider about any new symptoms. Liver disease might throat. Your pharmacist will give you a Warning Card with a list of get worse in patients who are taking HIV-1 medicines and interferon. these symptoms. Carry this Warning Card with you at all times. Who should not take TRIUMEQ? If you stop taking TRIUMEQ because of an allergic reaction, B:10.75” T:10.5” • Do not take TRIUMEQ if you: S:10” never take TRIUMEQ or any other medicine that contains have the HLA-B*5701 gene variation abacavir or dolutegravir again. If you take TRIUMEQ or any other have ever had an allergic reaction to abacavir, dolutegravir, or abacavir-containing medicine again after you have had an allergic lamivudine reaction, within hours you may get life-threatening symptoms that take dofetilide (Tikosyn®) may include very low blood pressure or death. If you stop TRIUMEQ have certain liver problems for any other reason, even for a few days, and you are not allergic to TRIUMEQ, talk with your healthcare provider before taking it again. What are other possible side effects of TRIUMEQ? • People with a history of hepatitis B or C virus may have an increased Taking TRIUMEQ again can cause a serious allergic or life-threatening Not an actual patient. Testimonial is based on risk of developing new or worsening changes in certain liver tests reaction, even if you never had an allergic reaction to it before. If your a collection of real patient experiences. healthcare provider tells you that you can take TRIUMEQ again, during treatment with TRIUMEQ. Your healthcare provider may do tests start taking it when you are around medical help or people who to check your liver function before and during treatment with TRIUMEQ. can call a healthcare provider if you need one. • When you start taking HIV-1 medicines, your immune system may get stronger and begin to fi ght infections that have been hidden in • A buildup of acid in your blood (lactic acidosis). Lactic acidosis What should I tell my healthcare provider before taking TRIUMEQ? can happen in some people who take TRIUMEQ. This serious your body for a long time. Tell your healthcare provider right away medical emergency can cause death. Call your healthcare provider if you start having new symptoms after starting your HIV-1 medicine. • Before you take TRIUMEQ, tell your healthcare provider if you: have been tested and know whether or not you have a gene variation called HLA-B*5701. right away if you feel very weak or tired; have unusual muscle • Changes in body fat can happen in people who take HIV-1 medicines. pain; have trouble breathing; have stomach pain with nausea and have or had liver problems, including hepatitis B or C infection; have kidney problems; • Some HIV-1 medicines, including TRIUMEQ, may increase your risk have heart problems, smoke, or have diseases that increase your risk of heart disease vomiting; feel cold, especially in your arms and legs; feel dizzy/light- of heart attack. headed; or have a fast/irregular heartbeat. such as high blood pressure, high cholesterol, or diabetes; drink alcoholic beverages; or The most common side effects of TRIUMEQ include: trouble have any other medical condition. • Severe liver problems. Severe liver problems can happen in people sleeping, headache, and tiredness. are pregnant or plan to become pregnant. It is not known if TRIUMEQ will harm your who take TRIUMEQ. In some cases, these severe liver problems can unborn baby. lead to death. You may be more likely to get lactic acidosis or serious These are not all the possible side effects of TRIUMEQ. Tell your are breastfeeding or plan to breastfeed. Do not breastfeed if you take TRIUMEQ. liver problems if you are female, very overweight, or have been taking healthcare provider if you have any side effect that bothers you or that nucleoside analogue medicines for a long time. Call your healthcare does not go away. • You should not take TRIUMEQ if you also take: abacavir (EPZICOM, TRIZIVIR, or ZIAGEN) provider right away if you get any of the following signs or symptoms: Important Safety Information continued on next page. ® ® lamivudine (COMBIVIR , EPIVIR, EPIVIR-HBV , EPZICOM, or TRIZIVIR) ® ® ® ® ® You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088. emtricitabine (EMTRIVA , ATRIPLA , COMPLERA , STRIBILD , TRUVADA ) Please see brief summary of Prescribing Information for TRIUMEQ on the following pages. • Tell your healthcare provider about all the medicines you take, including prescription and nonprescription medicines (for example, antacids; laxatives; vitamins such as iron or calcium supplements; anti-seizure medicines; other medicines to treat HIV-1, hepatitis, or ©2014 ViiV Healthcare group of companies. All rights reserved. tuberculosis; metformin; and methadone) and herbal supplements (for example, St. John’s Printed in USA. DTR045R0 November 2014 wort). TRIUMEQ may affect the way they work, and they may affect how TRIUMEQ works. FS:7” FS:7” F:8” F:8” Client Name: GSK/Triumeq Healthcare This advertisement prepared by: Product: Triumeq Havas Worldwide Job Number: 200 Hudson Street 65013 Filename 65013_58522_M02_DTR045R0_CouchSpread_ Last Modified 1-14-2015 12:41 PM User / PrevUs- Derrick.Edwin / Aileen.Boyce Client GSK Triumeq Art Director M. Culbreth Bleed 16.25” x 10.75” Path Premedia:Volumes:Premedia:Pre- CMYK press:65013_58522:Final:Pre- 0000065013_0000058522_M02_DTR045R0_FCAD – Positively Aware New York, New York 10013 Create 1-14-2015 10:42 AM Artist Kerry Trim 16” x 10.5” press:65013_58522_M02_DTR045R0_ CouchSpread_FCAD-for PREPRESS. Proof Caption: “I have the courage to start HIV…” (Man on Couch) 3 Traffic R. 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