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School of Medicine Table of Contents School of Medicine ................................................................................. 2 Anesthesiology and Perioperative Medicine .................................. 12 Department of Anatomy ................................................................. 15 Department of Biochemistry ........................................................... 19 Department of Bioethics ................................................................. 28 Department of Genetics ................................................................. 37 Department of Neurosciences ........................................................ 42 Department of Nutrition .................................................................. 45 Department of Pathology ............................................................... 52 Department of Pharmacology ........................................................ 62 Department of Physiology and Biophysics ..................................... 68 Doctor of Medicine (MD) ................................................................ 74 Dual Degree Programs .................................................................. 86 Environmental Health Sciences ..................................................... 91 Epidemiology and Biostatistics ....................................................... 92 General Medical Sciences ........................................................... 110 Graduate Programs in the Biomedical Sciences .......................... 125 Molecular Biology and Microbiology ............................................. 127 Molecular Medicine Program ....................................................... 132 School of Medicine Faculty .......................................................... 135 Index ................................................................................................... 240 2 School of Medicine • Earl W. Sutherland Jr., MD, who had been professor and director School of Medicine of pharmacology from 1953 to 1963, won the 1971 Nobel Prize in Physiology or Medicine for establishing the identity and importance The mission of the Case Western Reserve University School of Medicine of cyclic adenosine monophosphate (AMP) in the regulation of cell (http://casemed.case.edu) is to advance the health of humankind through metabolism. the four interrelated components of Education, Research, Clinical Care • Paul Berg, PhD, who earned his biochemistry degree at the university and Public Service. in 1952, received the 1980 Nobel Prize in Chemistry for pioneering research in recombinant DNA technology. The School of Medicine provides two tracks leading to the MD degree: • H. Jack Geiger, MD, a 1958 alumnus of the medical school, is the longstanding School of Medicine program, also called the University a founding member and past president of Physicians for Social track, and the Cleveland Clinic Lerner College of Medicine at Case Responsibility, which shared the 1985 Nobel Peace Prize as part Western Reserve University, also known as the College track, which of International Physicians for the Prevention of Nuclear War, and first admitted students in 2004. The School boasts a longstanding Physicians for Human Rights (PHR), which shared the 1997 Nobel Medical Scientist Training Program, or MSTP, and, through the School of Peace Prize as part of the International Campaign to Ban Landmines. Graduate Studies, programs resulting in PhD and MS degrees, as well as • George H. Hitchings, PhD, who had been a biochemistry instructor certificates in disciplines led by faculty in the School of Medicine. from 1939 to 1942, shared the 1988 Nobel Prize in Physiology or As a research institution, the School of Medicine has a tradition of Medicine for research leading to the development of drugs to treat national leadership. The School of Medicine consistently ranks in the leukemia, organ transplant rejection, gout, the herpes virus and AIDS- top tier of the nation’s medical schools for federal research funding from related bacterial and pulmonary infections. the National Institutes of Health, and is proud of its Clinical Translational • Alfred G. Gilman, MD, PhD, a 1969 graduate of the medical school, Service Award in partnership with its affiliates. In fiscal year 2010, the shared the 1994 Nobel Prize for Physiology or Medicine for identifying School earned more than $340 million in grants from the NIH including the role of G proteins in cell communication. grants through the affiliated Cleveland Clinic Lerner College of Medicine. • Ferid Murad, MD, PhD, a 1965 graduate of the medical school, Faculty and trainee research is routinely reported in the nation’s top shared the 1998 Nobel Prize in Physiology or Medicine for discoveries journals, leading to biomedical discoveries and improved health. concerning nitric oxide as a signaling molecule in the cardiovascular system. The School of Medicine engages the community in public service in • Paul C. Lauterbur, PhD, a 1951 graduate of the engineering school many ways. The School of Medicine’s commitment links researchers and a visiting professor of radiology at Case in 1993, shared the and medical students to the community. The school’s faculty provide 90 2003 Nobel Prize in Physiology or Medicine for pioneering work in the percent of the indigent health care in Cuyahoga County and a majority development of magnetic resonance imaging. of the care for indigent patients in Ohio. A major economic influence on the northern Ohio area, the School of Medicine and its affiliated • Peter C. Agre, MD, who completed a fellowship in hematology at Case hospitals are among the largest employers of personnel in the area and while a medical student at Johns Hopkins, shared the 2003 Nobel further stimulate the economy by providing concepts for technology Prize in Chemistry for discoveries that have clarified how salts and transfer to the business sector. On the international level, the School of water are transported out of and into the cells of the body, leading to a Medicine has a global health and diseases program focusing on AIDS, better understanding of many diseases of the kidneys, heart, muscles tuberculosis, malaria and other diseases that directly threaten world and nervous system. health. Two other distinguished alumni have served as U.S. surgeon general: The school is very proud of the contributions made by its educators Jesse Steinfeld, MD, a 1949 graduate, was surgeon general from 1969 and graduates but doesn’t rest on its laurels. The curriculum constantly to 1973, and David Satcher, MD, PhD, who graduated in 1970 and was responds to the latest findings in education and medicine and sets the surgeon general from 1998 to 2002. pace for other schools with input from gifted and committed scholars. Dr. Satcher also served as director of the Centers for Disease Control At least eleven Nobel Prize holders have ties to the School of Medicine: and Prevention from 1993 to 1998, and another medical school graduate, Julie Gerberding, MD, MPH, followed in his footsteps, in 2002 becoming • John J.R. Macleod, MB, ChB, DPH, physiology professor at Case the first woman to be named CDC director. from 1903 to 1918, shared the 1923 Nobel Prize in Physiology or Medicine for the discovery of insulin. Dr. Macleod completed much of History his groundwork on diabetes in Cleveland. Since its founding in 1843, the Case Western Reserve University School • Corneille J.F. Heymans, MD, who was a visiting scientist in the of Medicine has been an innovator in medical education and a leader in Department of Physiology in 1927 and 1928, received the Nobel Prize pioneering research. Beginning as the Medical Department of Western in Physiology or Medicine in 1938 for work on carotid sinus reflexes. Reserve College (and popularly known then as the Cleveland Medical • Frederick C. Robbins, MD, shared the 1954 Nobel Prize in Physiology College), the school moved into its first permanent home, in downtown or Medicine for his work on the polio virus, which led to the Cleveland, in 1846. In 1915, a 20-acre site was secured for a medical development of polio vaccines. He received the award two years after center in University Circle, the current home of Case Western Reserve joining the medical school. Dr. Robbins was active at the school until University, its School of Medicine, and two of the school’s affiliated his death in 2003, at which time he held the titles of medical school hospitals, University Hospitals of Cleveland and the Louis Stokes dean emeritus, University Professor emeritus, and emeritus director of Cleveland Department of Veterans Affairs Medical Center. University the Center for Adolescent Health. Circle also is home to many of the country’s outstanding cultural and educational institutions. Case Western Reserve University 3 The school was one of the first medical schools in the country to employ Wolstein Research Building, adding 320,000 square feet of space for up instructors devoted to full-time teaching and research. Six of the first to 700 researchers. seven women to receive medical degrees from accredited American medical schools graduated from Western Reserve College (as it was called then) between 1850 and 1856. Affiliated Hospitals Already a leading educational institution for more than a century, in 1952 University Hospitals (http:// the School of Medicine initiated the most advanced medical curriculum in www.uhhospitals.org) the country, pioneering integrated education, a focus on organ systems and team teaching in the preclinical
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