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Table of Contents Case Western Reserve University 1 Table of Contents School of Medicine ..................................................................................... 2 Anesthesiology and Perioperative Medicine .......................................................... 25 Department of Anatomy ........................................................................................... 31 Department of Biochemistry .................................................................................... 38 Department of Bioethics ........................................................................................... 52 Department of Genetics ............................................................................................ 63 Department of Neurosciences ................................................................................. 73 Department of Nutrition ............................................................................................ 78 Department of Pathology ......................................................................................... 89 Department of Pharmacology ................................................................................ 101 Department of Physiology and Biophysics .......................................................... 111 Doctor of Medicine (MD) ........................................................................................ 121 Dual Degree Programs ........................................................................................... 140 Environmental Health Sciences ............................................................................. 149 Epidemiology and Biostatistics ............................................................................. 152 General Medical Sciences ...................................................................................... 181 Graduate Programs in the Biomedical Sciences ................................................. 203 Molecular Biology and Microbiology .................................................................... 206 Molecular Medicine Program ................................................................................. 218 School of Medicine Faculty .................................................................................... 222 2 School of Medicine School of Medicine The mission of the Case Western Reserve • John J.R. Macleod, MB, ChB, DPH, physiology University School of Medicine (http:// professor at Case from 1903 to 1918, shared casemed.case.edu/) is to advance the health the 1923 Nobel Prize in Physiology or Medicine of humankind through the four interrelated for the discovery of insulin. Dr. Macleod components of Education, Research, Clinical Care completed much of his groundwork on diabetes in and Public Service. Cleveland. School of Medicine faculty lead two programs • Corneille J.F. Heymans, MD, who was a visiting leading to the MD at the School of Medicine, scientist in the Department of Physiology in 1927 including the the longstanding School of Medicine and 1928, received the Nobel Prize in Physiology program also called the University Program, and or Medicine in 1938 for work on carotid sinus the Cleveland Clinic Lerner College of Medicine reflexes. at Case Western Reserve University, also known as the College Program. The School boasts a • Frederick C. Robbins, MD, shared the 1954 longstanding Medical Scientist Training Program Nobel Prize in Physiology or Medicine for or MSTP, and through the School of Graduate his work on the polio virus, which led to the Studies, programs resulting in PhD and MS development of polio vaccines. He received the degrees, as well as certificates in disciplines led by award two years after joining the medical school. faculty in the School of Medicine. Dr. Robbins was active at the school until his death in 2003, at which time he held the titles As a research institution, the School of Medicine of medical school dean emeritus, University has a tradition of national leadership. The School Professor emeritus, and emeritus director of the of Medicine consistently ranks in the top tier of Center for Adolescent Health. the nation’s medical schools for federal research funding from the National Institutes of Health, • Earl W. Sutherland Jr., MD, who had been and is proud of its Clinical Translational Service professor and director of pharmacology from Award in partnership with its affiliates. In fiscal year 1953 to 1963, won the 1971 Nobel Prize in 2010, the School earned more than $340 million in Physiology or Medicine for establishing the grants from the NIH including grants through the identity and importance of cyclic adenosine affiliated Lerner College Cleveland Clinic College of monophosphate (AMP) in the regulation of cell Medicine. Faculty and trainee research is routinely metabolism. reported in the Nation’s top journals, leading to biomedical discoveries and improved health. • Paul Berg, PhD, who earned his biochemistry degree at the university in 1952, received the The School of Medicine engages the community 1980 Nobel Prize in Chemistry for pioneering in public service in many ways. The School of research in recombinant DNA technology. Medicine’s commitment links researchers and medical students to the community. The school’s • H. Jack Geiger, MD, a 1958 alumnus of the faculty provide 90 percent of the indigent health medical school, is a founding member and past care in Cuyahoga County and a majority of the care president of Physicians for Social Responsibility, for indigent patients in Ohio. A major economic which shared the 1985 Nobel Peace Prize as part influence on the northern Ohio area, the School of International Physicians for the Prevention of of Medicine and its affiliated hospitals are among Nuclear War, and Physicians for Human Rights the largest employers of personnel in the area (PHR), which shared the 1997 Nobel Peace Prize and further stimulate the economy by providing as part of the International Campaign to Ban concepts for technology transfer to the business Landmines. sector. On the international level, the School of Medicine has a global health and diseases program • George H. Hitchings, PhD, who had been a focusing on AIDS, tuberculosis, malaria and other biochemistry instructor from 1939 to 1942, shared diseases that directly threaten world health. the 1988 Nobel Prize in Physiology or Medicine The school is very proud of the contributions made for research leading to the development of drugs by its educators and graduates but doesn’t rest on to treat leukemia, organ transplant rejection, gout, its laurels. The curriculum constantly responds to the herpes virus and AIDS-related bacterial and the latest findings in education and medicine and pulmonary infections. sets the pace for other schools. At least eleven Nobel Prize holders have ties to the School of Medicine: Case Western Reserve University 3 • Alfred G. Gilman, MD, PhD, a 1969 graduate of The school was one of the first medical schools in the medical school, shared the 1994 Nobel Prize the country to employ instructors devoted to full- for Physiology or Medicine for identifying the role time teaching and research. Six of the first seven of G proteins in cell communication. women to receive medical degrees from accredited American medical schools graduated from Western • Ferid Murad, MD, PhD, a 1965 graduate of Reserve College (as it was called then) between the medical school, shared the 1998 Nobel 1850 and 1856. Prize in Physiology or Medicine for discoveries concerning nitric oxide as a signaling molecule in Already a leading educational institution for more the cardiovascular system. than a century, in 1952 the School of Medicine initiated the most advanced medical curriculum • Paul C. Lauterbur, PhD, a 1951 graduate of the in the country, pioneering integrated education, a engineering school and a visiting professor of focus on organ systems and team teaching in the radiology at Case in 1993, shared the 2003 Nobel preclinical curriculum. This curriculum instituted Prize in Physiology or Medicine for pioneering a pass/fail grading system for the first two years work in the development of magnetic resonance of medical school to promote cooperation among imaging. students instead of competitiveness, introduced students to clinical work and patients almost as • Peter C. Agre, MD, who completed a fellowship soon as they arrived on campus, and provided free, in hematology at Case while a medical student unscheduled time in an era when doing so seemed at Johns Hopkins, shared the 2003 Nobel Prize unthinkable. Many other medical schools followed in Chemistry for discoveries that have clarified suit, and these components remain at the core of how salts and water are transported out of and the medical school’s curriculum today. into the cells of the body, leading to a better understanding of many diseases of the kidneys, In 1924, the School of Medicine moved into the heart, muscles and nervous system. most modern and best-equipped preclinical science building in the country at that time. That building, donated by Cleveland industrialist Samuel Mather, Two other distinguished alumni have served as remains an integral part of the medical school U.S. surgeon general: Jesse Steinfeld, MD, a 1949 complex. It was named the Harland Goff Wood graduate, was surgeon general from 1969 to 1973, Building in 1993 in honor of the late chair and and David Satcher, MD, PhD, graduated in 1970 professor of biochemistry and former provost of the and was surgeon general from
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