Curriculum Vitae
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SFB 1074 Renewal Application PI Profiles 2016-2020
General Information Name: Prof. Dr. med. Klaus-Michael Debatin Date of Birth: 06.12.1952 Gender: Male Address: Department of Pediatrics and Adolescent Medicine, Ulm University, Eythstrasse 24, 89075 Ulm/Germany Phone: +49 731 500 57001 E-Mail: [email protected] Current Positions: Chairman, Department of Pediatrics, Ulm University Medical Director, University Children’s Hospital Ulm Deputy Coordinating Investigator, Collaborative Research Center (SFB) 1074 “Experimental models and clinical translation in leukemia” Academic Education 1971 - 1978 Medical School, Universities of Ulm, Freiburg and Heidelberg Academic Degrees 1997 Professor of Pediatrics, Ulm University 1990 Habilitation in Pediatrics, University of Heidelberg 1979 Doctorate degree (Dr. med.), University of Heidelberg Professional Experience 2013-2015 CEO and Medical Director, University Medical Center Ulm 2010-2013 Deputy Medical Director, University Medical Center Ulm 2010-2014 Vice President Medicine, Ulm University 2004-2010 Dean, Medical Faculty, Ulm University 2003-2005 Chairman, Science Committee of the Medical Faculty, Ulm University 2002-2004 Vice Dean, Medical Faculty, Ulm University 1995-2002 Head, Division of Molecular Oncology, German Cancer Research Center 1997 Visiting Professor, St. Jude Children’s Research Hospital, Memphis Since 1997 Chairman, Department of Pediatrics, Ulm University Physician-in-chief of the University Children’s Hospital Ulm 1994-1997 Head, Hematology/Oncology Section, University Children's Hospital, Heidelberg 1990-1994 -
Case Study North Rhine-Westphalia
Contract No. 2008.CE.16.0.AT.020 concerning the ex post evaluation of cohesion policy programmes 2000‐2006 co‐financed by the European Regional Development Fund (Objectives 1 and 2) Work Package 4 “Structural Change and Globalisation” CASE STUDY NORTH RHINE‐WESTPHALIA (DE) Prepared by Christian Hartmann (Joanneum Research) for: European Commission Directorate General Regional Policy Policy Development Evaluation Unit CSIL, Centre for Industrial Studies, Milan, Italy Joanneum Research, Graz, Austria Technopolis Group, Brussels, Belgium In association with Nordregio, the Nordic Centre for Spatial Development, Stockholm, Sweden KITE, Centre for Knowledge, Innovation, Technology and Enterprise, Newcastle, UK Case Study – North Rhine‐Westphalia (DE) Acronyms BERD Business Expenditure on R&D DPMA German Patent and Trade Mark Office ERDF European Regional Development Fund ESF European Social Fund EU European Union GERD Gross Domestic Expenditure on R&D GDP Gross Domestic Product GRP Gross Regional Product GVA Gross Value Added ICT Information and Communication Technology IWR Institute of the Renewable Energy Industry LDS State Office for Statistics and Data Processing NGO Non‐governmental Organisation NPO Non‐profit Organisation NRW North Rhine‐Westphalia NUTS Nomenclature of Territorial Units for Statistics PPS Purchasing Power Standard REN Rational Energy Use and Exploitation of Renewable Resources R&D Research and Development RTDI Research, Technological Development and Innovation SME Small and Medium Enterprise SPD Single Programming Document -
Warburg Effect(S)—A Biographical Sketch of Otto Warburg and His Impacts on Tumor Metabolism Angela M
Otto Cancer & Metabolism (2016) 4:5 DOI 10.1186/s40170-016-0145-9 REVIEW Open Access Warburg effect(s)—a biographical sketch of Otto Warburg and his impacts on tumor metabolism Angela M. Otto Abstract Virtually everyone working in cancer research is familiar with the “Warburg effect”, i.e., anaerobic glycolysis in the presence of oxygen in tumor cells. However, few people nowadays are aware of what lead Otto Warburg to the discovery of this observation and how his other scientific contributions are seminal to our present knowledge of metabolic and energetic processes in cells. Since science is a human endeavor, and a scientist is imbedded in a network of social and academic contacts, it is worth taking a glimpse into the biography of Otto Warburg to illustrate some of these influences and the historical landmarks in his life. His creative and innovative thinking and his experimental virtuosity set the framework for his scientific achievements, which were pioneering not only for cancer research. Here, I shall allude to the prestigious family background in imperial Germany; his relationships to Einstein, Meyerhof, Krebs, and other Nobel and notable scientists; his innovative technical developments and their applications in the advancement of biomedical sciences, including the manometer, tissue slicing, and cell cultivation. The latter were experimental prerequisites for the first metabolic measurements with tumor cells in the 1920s. In the 1930s–1940s, he improved spectrophotometry for chemical analysis and developed the optical tests for measuring activities of glycolytic enzymes. Warburg’s reputation brought him invitations to the USA and contacts with the Rockefeller Foundation; he received the Nobel Prize in 1931. -
Chemotherapy for Breast Cancer
INFORMATION AND ADVICE Austria CHEMOTHERAPY Brustkrebs Deutschland e. V. Österreichische Krebshilfe-Gesellschaft [Breast Cancer Germany, registered association] [Austrian Cancer Aid Association] FOR BREAST CANCER – Lise-Meitner-Str. 7 Tuchlauben 19 HOW DO I DEAL 85662 Hohenbrunn (district of Munich) AT-1010 Vienna Tel.: +49 (0) 89 / 41 61 98 00 Tel.: +43 (0) 1 / 796 64 50 WITH SIDE EFFECTS? Fax: +49 (0) 89 / 41 61 98 01 Fax: +43 (0) 1 / 796 64 50-9 Free hotline: 0800 0 117 112 www.krebshilfe.net E-Mail: [email protected] DE-HAL-18-00041 (V2.0): 12/2020; HAL0129B www.brustkrebsdeutschland.de Switzerland Deutsche Krebsgesellschaft e. V. [German Cancer Association, registered association] Krebsliga Schweiz Kuno-Fischer-Str. 8 [Cancer League Switzerland] 14057 Berlin Effingerstrasse 40 Tel: + 49 (0) 30 322932-90 CH-3001 Bern Fax: + 49 (0) 30 3229329-22 Tel.: +41 (0) 31 389 91 00 www.krebsgesellschaft.de Fax: +41 (0) 31 389 91 60 [email protected] Krebsinformationsdienst Deutsches Krebsforschungszentrum Cancer telephone and helpline [Cancer Information Service Free hotline: +41 (0) 800 11 88 11 German Cancer Research Centre] E-mail: [email protected] Im Neuenheimer Feld 280 Forum: www.krebsforum.ch 69120 Heidelberg Free hotline: +49 (0) 800 / 420 30 40 www.krebsinformationsdienst.de Stiftung Deutsche Krebshilfe-Infonetz Krebs [German Cancer Aid Foundation-Cancer Information Network] Buschstr. 32 53113 Bonn Tel.: +49 (0) 800 / 80 70 88 77 (free of charge) Mon. to Fri. 8.00 – 17.00 www.infonetz-krebs.de Distribution in Germany: Distribution in Austria: Distribution in Switzerland: Englisch Eisai GmbH Eisai GesmbH, Saturn Tower Eisai Pharma AG Edmund-Rumpler-Straße 3 Leonard-Bernstein-Straße 10 Leutschenbachstrasse 95 60549 Frankfurt am Main A-1220 Vienna CH-8050 Zurich [email protected] [email protected] Tel.: +41 (0) 44 / 306 12 12 INTRODUCTION HELP WITH SELF-HELP Palliative chemotherapy: Therapy with cytostatics aimed at prolonging survival time and improving quality of life. -
Shrinking German Cities -The Cases of Halle and Gelsenkirchen
Master Thesis Shrinking German cities -The cases of Halle and Gelsenkirchen- Author: Nora Kaminski Supervisor: Jan-Evert Nilsson Tutor: Alina Lidén Submitted to Blekinge Tekniska Högskola for the Master of European Spatial Planning and Regional Development on the 13/04/2012 Abstract The thesis researches the reasons of shrinking cities, especially the impact of deindustrialisation, in Germany using the example of Halle and Gelsenkirchen. Additionally, the policy response towards this phenomenon in terms of urban consolidation in the cities is posed. For doing that, the economic history of the towns is investigated and simultaneously the development of population and of unemployment is researched, as they are closely connected to the economy. With an analysis of the proportion of employees in the different economic sectors in the course of time the structural change becomes more obvious. A shifting has taken place: both cities engage currently more people in the tertiary sector and less people in the secondary sector as twenty years ago. Concluding all indicators it can be said that a deindustrialisation took place. However, also other influences on shrinking, as for example migration, are described and their impact on both cities is explained. With investigating the consolidation areas of the programme Stadtumbau Ost and Stadtumbau West in Halle and Gelsenkirchen the possible course of action by the policy is presented and those areas in Halle and Gelsenkirchen are identified, which have the biggest population decline and the highest vacancy rates. Critique about the Stadtumbau programme is given at the end of the research. The result of the analysis is that deindustrialisation can explain big parts of the shrinking process in both cities. -
Düsseldorf - Duisburg
RE3 RE RE3 Rhein-Emscher Express DB-Kursbuchstrecke: 416 und zurück Gelsenkirchen - Dortmund Düsseldorf - Duisburg DüsseldorfD-Flughafen Hbf Duisburg OberhausenHbf E-Altenessen Hbf GelsenkirchenWanne-Eickel Hbf Herne Hbf Bf Castrop-RauxelDO-Mengede HbfDortmundDO-Scharnhorst Hbf DO-Kurl Kamen-MethlerKamen NordböggeHamm (Westf) Hamm P+R P+R P+R P+R P+R P+R P+R P+R P+R P+R P+R P+R P+R und zurück Anschlüsse siehe Haltestellenverzeichnis/Linienplan Fahrradmitnahme begrenzt möglich RE RE3 RE RE3 montags bis freitags RE3 Haltestellen Abfahrtszeiten Düsseldorf Hbf ab 4.45 9.45 10.45 11.45 18.45 19.45 23.45 Gelsenkirchen - Dortmund Düsseldorf - Duisburg D-Flughafen Bf an 4.52 9.52 10.52 11.52 18.52 19.52 23.52 D-Flughafen Bf ab 4.53 9.53 10.53 11.53 18.53 19.53 23.53 Duisburg Hbf an 5.03 10.03 11.03 12.03 19.03 20.03 0.03 Duisburg Hbf ab 5.10 10.10 11.10 12.10 19.10 20.10 0.10 Oberhausen Hbf an 5.15 10.15 11.15 12.15 19.15 20.15 0.15 Oberhausen Hbf ab 5.16 10.16 11.16 12.16 19.16 20.16 alle 0.16 Essen Altenessen Bf 23 23 23 23 23 2360 23 Gelsenkirchen Hbf an 5.28 10.28 11.28 12.28 19.28 20.28 Min. 0.28 Gelsenkirchen Hbf ab 5.29 10.29 11.29 12.29 19.29 20.29 0.29 HER Wanne-Eickel Hbf an 5.33 alle 10.33 11.33 12.33 alle 19.33 20.33 0.33 HER Wanne-Eickel Hbf 3460 34 34 3460 34 34 34 Herne Bf 38Min. -
Gelsenkirchen
C-Change City Profile Gelsenkirchen City of Gelsenkirchen, by Armin Hardes UNDERSTANDING THE CITY • At the heart of the Ruhr metropolis, one of Europe’s largest conurbations • An independent city administration in the federal state of North Rhine-Westphalia, member of the Regionalverband Ruhr, the regional association of the 53 cities of the Ruhr metropolis • Once the most important coal-mining town in Europe, known as the ‘city of a thousand flames’ • Target of heavy bombing during World War II • A wealthy city until the 1960s and the decline of the coal industry • A population of 5,000 people in 1840 when coal-mining began which, following a long history of immigration, reached 389,000 in 1960, decreased to 256,000 in 2012, and is now increasing, in particular due to immigration from EU member states and refugee settlement • Transformation in natural and built environment and industrial and cultural landscape as a result of a major federal programme of structural change for the Ruhr region 1988-1999 • “Solar City”, one of Germany’s leading centres for solar technology from about 1995-2015 • Part of the Ruhr 2010 European Capital of Culture 2010, a key moment in the city and the region’s journey from an economy based on coal to a culturally creative and economically varied region • A relatively poor city, dealing with the legacy of a ban on universities in the region until the 1960s, and the lack of a strong middle class and facing issues in the areas of education, employment and immigration • City strategy is focused on education, high-tech industries, culture and creativity, digitalisation, European networking, sustainable development and climate change • Football plays a big part in the city, which is home to the famous Schalke 04 football club. -
Closer to Europe — Tremendous Opportunities Close By: Germany Is Applying Interview – a Conversation with Bfarm Executive Director Prof
CLOSER TO EUROPE The new home of the European Medicines U E Agency (EMA) should be located centrally . E within Europe. Optimally accessible. P Set within a strong neigh bourhood. O R Germany is applying for the city of Bonn, U E at the heart of the European - O T Rhine Region, to be the location - R E of the EMA’s new home. S LO .C › WWW FOREWORD e — Federal Min öh iste Gr r o nn f H a e rm al e th CLOSER H TO EUROPE The German application is for a very European location: he EU 27 will encounter policy challenges Healthcare Products Regulatory Agency. The Institute Bonn. A city in the heart of Europe. Extremely close due to Brexit, in healthcare as in other ar- for Quality and Efficiency in Health Care located in T eas. A new site for the European Medicines nearby Cologne is Europe’s leading institution for ev- to Belgium, the Netherlands, France and Luxembourg. Agency (EMA) must be found. Within the idence-based drug evaluation. The Paul Ehrlich Insti- Situated within the tri-state nexus of North Rhine- EU, the organisation has become the primary centre for tute, which has 800 staff members and is located a mere drug safety – and therefore patient safety. hour and a half away from Bonn, contributes specific, Westphalia, Hesse and Rhineland-Palatinate. This is internationally acclaimed expertise on approvals and where the idea of a European Rhine Region has come to The EMA depends on close cooperation with nation- batch testing of biomedical pharmaceuticals and in re- life. -
The Prevention, Detection and Treatment of Cancer Are Preeminent Goals in Health Policy
No. 14 April 2, 2014 (Koh) 50 years of research for life without cancer "The prevention, detection and treatment of cancer are preeminent goals in health policy. The DKFZ is the flagship of cancer research in Germany. It has brought forward the development of new approaches in the prevention, diagnosis and treatment of cancer. The DKFZ is an institution that, ever since its inception, has promoted creativity and helped innovative ideas flourish. I congratulate the DKFZ with all its employees on these accomplishments." These were the opening words of the Federal Minister of Education and Research, Prof. Dr. Johanna Wanka, in her welcome address at a press conference held in Berlin on the occasion of the 50th anniversary of the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ). "The German Cancer Research Center (DKFZ), founded in 1964 in Heidelberg as a national research institute, has seen astonishing changes over those 50 years and has evolved into an internationally renowned center of high-end research," said Otmar Wiestler, Chairman of the Management Board and Scientific Director of DKFZ. From the very beginning, the Center, which was initially not linked to clinics, has had a double mission: to conduct research on the basic biological mechanisms of cancer and translate the results of its research into enhanced methods for the prevention, diagnosis and treatment of cancer. While the initial years were clearly focused on basic research, the DKFZ has gone on to achieve amazing accomplishments in the translation of its research findings into clinical applications. A crucial factor that has facilitated this development was the foundation of the National Center for Tumor Diseases (NCT) Heidelberg in collaboration with Heidelberg University Hospitals and German Cancer Aid (Deutsche Krebshilfe). -
Guide to the James Franck Papers 1882-1966
University of Chicago Library Guide to the James Franck Papers 1882-1966 © 2006 University of Chicago Library Table of Contents Acknowledgments 3 Descriptive Summary 3 Information on Use 3 Access 3 Citation 3 Biographical Note 4 Scope Note 15 Related Resources 21 Subject Headings 21 INVENTORY 22 Series I: Correspondence 22 Series II: Manuscripts 51 Subseries 1: Physics - work in Germany and Denmark, 1905-1934 51 Subseries 2: Physics - work in United States, 1935-1958 53 Subseries 3: Biophysics - work on Photosynthesis at Johns Hopkins, 1935-193855 Subseries 4: Biophysics - work on Photosynthesis at the University of Chicago,55 1938-48 Subseries 5: Biophysics - work on Photosynthesis after 1948 55 Subseries 6: General Articles and Talks on Science 71 Subseries 7: Papers by other scientists 72 Subseries 8: Notes, memoranda and fragments 76 Subseries 9: Atomic Scientists' Movement, 1944-1953 76 Subseries 10: Franck Memorial Symposium, May 12-13, 1966 79 Series III: Tape Recordings and Photographs 80 Subseries 1: Tape recordings 80 Subseries 2: Hertha Sponer's photograph album, Göttingen, 1920-1933 80 Series IV: Personal Documents and Memorabilia 90 Subseries 1: Documents 90 Subseries 2: Clippings 93 Subseries 3: Biographies and Obituaries 94 Subseries 4: Memorabilia; Scrolls, Certificates, Medals, Mementos 96 Series V: Robert Platzman's Editorial Papers for the "Selected Works of James98 Franck" Series VI: Addenda 103 Subseries 1: Correspondence between James Franck and his nephew and Dr. Heinz104 Kallman Subseries 2: Oversize 105 Descriptive Summary Identifier ICU.SPCL.FRANCK Title Franck, James. Papers Date 1882-1966 Size 20.5 linear feet (29 boxes) Repository Special Collections Research Center University of Chicago Library 1100 East 57th Street Chicago, Illinois 60637 U.S.A. -
Final Program and Book of Abstracts
JOINT MEETING OF THE AUSTRIAN AND GERMAN PHARMACEUTICAL SOCIETIES September 20 – 23, 2011 University of Innsbruck, Austria "Shaping the future – Trends and perspectives in pharmaceutical sciences" FINAL PROGRAM AND BOOK OF ABSTRACTS ORGANIZATION Presidents Prof. H. Stuppner, Innsbruck (ÖPhG) Prof. M. Schubert-Zsilavecz (DPhG) Organizing Committee Prof. G. Ecker (Austria) Prof. S. Glasl-Tazreiter (Austria) Prof. U. Griesser (Austria) Ing. E. Gstrein (Austria) S. Handke (Germany) Dr. T. Maschke (Germany) Dr. S. Schwaiger (Austria) Dr. M. Stein (Germany) Scientific Committee Prof. S. Alban (Vice President, DPhG) Prof. R. Bauer (Graz, Austria) Prof. A. Bernkop-Schnürch (Innsbruck, Austria) Prof. T. Dingermann (Frankfurt, Germany) Prof. Dr. V. Dirsch (Vienna, Austria) Prof. G. Ecker (Vice President,ÖPhG) Prof. S. Glasl-Tazreiter (General Secretary, ÖPhG) Prof. R. Gust (Innsbruck, Austria) Prof. U. Holzgrabe (Würzburg, Germany) Prof. A. Kungl (Graz, Austria) Prof. R. Lemmens-Gruber (Vienna, Austria) Prof. A. Link (General Secretary, DPhG) Prof. C. Noe (Vienna, Austria) Prof. M. Schubert-Zsilavecz (President, DPhG) Prof. N. Singewald (Innsbruck, Austria) Prof. D. Steinhilber (Frankfurt, Germany) Prof. H. Stuppner (President, ÖPhG) Prof. H. Viernstein (Vienna, Austria) Prof. O. Werz (Jena, Germany) Prof. A. Zimmer (Graz, Austria) Organizing Secretariat University of Innsbruck Institute of Pharmacy/Pharmacognosy Innrain 52c A-6020 Innsbruck Email: [email protected] Homepage: www.uibk.ac.at/news/oephg-dphg2011 CONFERENCE VENUES University -
Immunosensation the Immune Sensory System Bonn Cluster of Excellence
ImmunoSensation the immune sensory system Bonn cluster of excellence ANNUAL REPORT 2013 G Ap(3’-5’)G Gp(2’-5’)A A cGAMP DNA cGAS pppGp(2'-5')A GTP ATP universitätbonn ANNUAL REPORT 2013 Preface p. 8 OVERVIEW Overview: Science and Structure p. 12 Scientific Reports – Research Highlights DNA Sensing and Oxidative Damage p. 16 Local Immune Regulation in Tissues p. 24 Sterile Inflammation in the Nervous System and Metabolism p. 36 Immune Sensing and Responses in Tumor Biology p. 50 Feature Article: Immunity and Aerospace Medicine p. 56 Interviews p. 60 Dean of the Medical Faculty: Prof. Max Baur, MD p. 61 Speaker: Prof. Gunther Hartmann, MD p. 64 Vice-Speaker: Prof. Waldemar Kolanus, PhD p. 66 Postdoc: Katharina Hochheiser, PhD p. 68 PhD Student: Larisa Labzin p. 72 Head of the Flow Cytometry Core Facility: Dr. Elmar Endl p. 76 Cluster Coordination Reports p. 80 Family Support & Gender Equality p. 81 Young Investigator Support p. 86 Public Relations p. 90 Events p. 92 First Retreat of the ImmunoSensation Cluster in St. Goar p. 93 Cluster Seminars p. 95 ImmunoSensation visits ELSC/Israel p. 98 Cluster Science Day p. 102 Prizewinners of the Cluster Science Day p. 104 List of Publications p. 110 Seminars & Meetings p. 124 Prizes & Distinctions p. 128 List of Cluster Members p. 132 Biosketches p. 140 Impressions Retreat St. Goar p. 168 Organigram – Structure of the Cluster p. 170 Participating Institutions p. 172 Cluster Coordination Office (CCO) p. 174 Imprint p. 176 Preface Preface We can now look back on the first year just at the edge of a profound conceptual of funding of our Cluster of Excellence advance arising from new interactions ImmunoSensation by the German within the Cluster, such as the one Research Foundation, DFG.