CAPN9 Antibody Cat. No.: 15-200

CAPN9 Antibody

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human, Mouse, Rat

Recombinant fusion containing a sequence corresponding to amino acids 391-690 IMMUNOGEN: of human CAPN9 (NP_006606.1).

TESTED APPLICATIONS: WB

APPLICATIONS: WB: ,1:500 - 1:2000

POSITIVE CONTROL: 1) SGC-7901

2) HL-60

3) HT-29

4) Mouse stomach

5) Mouse small intestine

6) Rat stomach

PREDICTED MOLECULAR Observed: 79kDa WEIGHT:

Properties

September 28, 2021 1 https://www.prosci-inc.com/capn9-antibody-15-200.html PURIFICATION: Affinity purification

CLONALITY: Polyclonal

ISOTYPE: IgG

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles.

Additional Info

OFFICIAL SYMBOL: CAPN9

Calpain-9, 3422-, Digestive tract-specific , New calpain 4, nCL-4, Protein CG36, ALTERNATE NAMES: CAPN9, NCL4

GENE ID: 10753

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine . The calpain are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine domain, and both subunits possess calcium-binding domains. have been implicated in BACKGROUND: neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

ANTIBODIES FOR RESEARCH USE ONLY.

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September 28, 2021 2 https://www.prosci-inc.com/capn9-antibody-15-200.html