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Tribulus Terrestris Extract 40% Saponins Tribulus Terrestris Extract 40% Saponins Cambridge Commodities Chemwatch Hazard Alert Code: 2 Part Number: P2004 Issue Date: 05/11/2019 Version No: 1.2.23.11 Print Date: 24/09/2021 Safety data sheet according to REACH Regulation (EC) No 1907/2006, as amended by UK REACH Regulations SI 2019/758 S.REACH.GB.EN SECTION 1 Identification of the substance / mixture and of the company / undertaking 1.1. Product Identifier Product name Tribulus Terrestris Extract 40% Saponins Chemical Name Not Applicable Synonyms Not Available Chemical formula Not Applicable Other means of P2004 identification 1.2. Relevant identified uses of the substance or mixture and uses advised against Antioxidant. Saponins: are being promoted commercially as dietary supplements and food ingredients. However there are very limited US, EU, etc. agency-approved roles for saponins in human therapy. Therapeutic benefit is a result of careful administration of an appropriate dose. Very great care needs to be exercised in evaluating or acting on specific claims of therapeutic benefit from ingesting saponin-type and other natural products. are poisonous towards lower life forms. have been reported to provide a hypocholesteremic effect (caused by low levels of blood cholesterol) by inhibiting the passive diffusion of colic acid through the formation of micelles thus preventing absorption, anticancer, antiparasitic and anti-inflammatory properties are used widely for their effects on ammonia emissions in animal feeding. The mode of action seems to be an inhibition of the urease enzyme, which splits up excreted urea in faeces into ammonia and carbon dioxide. Animal trials have shown that a reduced ammonia level in farming operations causes less damages to the respiratory tract of animals, and may help to make Relevant identified uses them less vulnerable to diseases. have also been used as adjuvants in vaccines. In their use as adjuvants in the production of vaccines, toxicity associated with sterol complexation remains a major issue for attention. form complexes with cholesterol to form pores in cell membrane bilayers, e.g., in red cell (erythrocyte) membranes - complexation leads to red cell lysis (haemolysis) on intravenous injection. In addition, the amphipathic nature of the class gives them activity as surfactants that can be used to enhance penetration of macromolecules such as proteins through cell membranes. are amphipathic glycosides (having both a water and fat soluble ends) grouped phenomenologically by the soap-like foaming they produce when shaken in aqueous solutions. are bitter-tasting and foam strongly when shaken in water. They form oil-in-water emulsions and act as collective colloids. Saponins (sapinogen glycosides) and sapogenins are widely distributed in plants. Each saponin consists of an aglucone moiety (the sapogenin), a sugar and a glycoside. The sapinogenin may be a steroid or a triterpene (unsaturated hydrocarbons based on the isoprene unit H2CC(CH3)CH CH2) and with structures similar to that of steroid hormones), and the sugar may be glucose, Product code: P2004 Version No: 1.2.23.2 Page 1 of 25 S.REACH.GB.EN Lancaster Way Business Park Safety Data Sheet (Conforms to Regulation (EU) No 2020/878) Ely, Cambridgeshire, CB6 3NX, UK. Chemwatch: 9-700281 +44 (0) 1353 667258 Issue Date: 05/11/2019 [email protected] Print Date: 24/09/2021 www.c-c-l.com galactose, a pentose or a methylpentose. Uses advised against Not Applicable 1.3. Details of the supplier of the safety data sheet Registered company name Cambridge Commodities Address Lancaster Way Business Park, Ely, Cambridgeshire Cambridgeshire CB6 3NX United Kingdom Telephone +44 1353 667258 Fax Not Available Website Not Available Email [email protected] 1.4. Emergency telephone number Association / Organisation Not Available Emergency telephone Not Available numbers Other emergency Not Available telephone numbers SECTION 2 Hazards identification 2.1. Classification of the substance or mixture Classified according to GB-CLP Regulation, UK SI H335 - Specific Target Organ Toxicity - Single Exposure (Respiratory Tract Irritation) Category 3, H315 - Skin Corrosion/Irritation 2019/720 and UK SI Category 2, H319 - Serious Eye Damage/Eye Irritation Category 2 2020/1567 [1] Legend: 1. Classified by Chemwatch; 2. Classification drawn from GB-CLP Regulation, UK SI 2019/720 and UK SI 2020/1567 2.2. Label elements Hazard pictogram(s) Signal word Warning Hazard statement(s) H335 May cause respiratory irritation. H315 Causes skin irritation. H319 Causes serious eye irritation. Supplementary statement(s) Product code: P2004 Version No: 1.2.23.2 Page 2 of 25 S.REACH.GB.EN Lancaster Way Business Park Safety Data Sheet (Conforms to Regulation (EU) No 2020/878) Ely, Cambridgeshire, CB6 3NX, UK. Chemwatch: 9-700281 +44 (0) 1353 667258 Issue Date: 05/11/2019 [email protected] Print Date: 24/09/2021 www.c-c-l.com Not Applicable Precautionary statement(s) Prevention P271 Use only outdoors or in a well-ventilated area. P261 Avoid breathing dust/fumes. P280 Wear protective gloves, protective clothing, eye protection and face protection. P264 Wash all exposed external body areas thoroughly after handling. Precautionary statement(s) Response P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312 Call a POISON CENTER/doctor/physician/first aider/if you feel unwell. P337+P313 If eye irritation persists: Get medical advice/attention. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P332+P313 If skin irritation occurs: Get medical advice/attention. P362+P364 Take off contaminated clothing and wash it before reuse. Precautionary statement(s) Storage P405 Store locked up. P403+P233 Store in a well-ventilated place. Keep container tightly closed. Precautionary statement(s) Disposal P501 Dispose of contents/container to authorised hazardous or special waste collection point in accordance with any local regulation. 2.3. Other hazards Inhalation and/or ingestion may produce health damage*. Cumulative effects may result following exposure*. Possible skin sensitizer*. REACh - Art.57-59: The mixture does not contain Substances of Very High Concern (SVHC) at the SDS print date. SECTION 3 Composition / information on ingredients 3.1.Substances See 'Composition on ingredients' in Section 3.2 3.2.Mixtures 1.CAS No 2.EC No Classified according to GB-CLP Regulation, UK SI 2019/720 and Nanoform Particle %[weight] Name 3.Index No UK SI 2020/1567 Characteristics 4.REACH No 1.8047-15-2 Skin Corrosion/Irritation Category 2, Serious Eye Damage/Eye 2.232-462-6 40 saponin Irritation Category 2, Specific Target Organ Toxicity - Single Not Available Product code: P2004 Version No: 1.2.23.2 Page 3 of 25 S.REACH.GB.EN Lancaster Way Business Park Safety Data Sheet (Conforms to Regulation (EU) No 2020/878) Ely, Cambridgeshire, CB6 3NX, UK. Chemwatch: 9-700281 +44 (0) 1353 667258 Issue Date: 05/11/2019 [email protected] Print Date: 24/09/2021 www.c-c-l.com 1.CAS No 2.EC No Classified according to GB-CLP Regulation, UK SI 2019/720 and Nanoform Particle %[weight] Name 3.Index No UK SI 2020/1567 Characteristics 4.REACH No 3.Not Available Exposure (Respiratory Tract Irritation) Category 3; H315, H319, 4.Not Available H335 [1] 1.Not Available Tribulus 2.Not Available 55 Terrestris Not Applicable Not Available 3.Not Available Extract 4.Not Available 1.9050-36-6 2.232-940-4 5 maltodextrin Not Applicable Not Available 3.Not Available 4.Not Available Legend: 1. Classified by Chemwatch; 2. Classification drawn from GB-CLP Regulation, UK SI 2019/720 and UK SI 2020/1567; 3. Classification drawn from C&L; * EU IOELVs available; [e] Substance identified as having endocrine disrupting properties SECTION 4 First aid measures 4.1. Description of first aid measures If this product comes in contact with the eyes: Wash out immediately with fresh running water. Ensure complete irrigation of the eye by keeping eyelids apart and away from eye and moving the eyelids by occasionally Eye Contact lifting the upper and lower lids. Seek medical attention without delay; if pain persists or recurs seek medical attention. Removal of contact lenses after an eye injury should only be undertaken by skilled personnel. If skin contact occurs: Immediately remove all contaminated clothing, including footwear. Skin Contact Flush skin and hair with running water (and soap if available). Seek medical attention in event of irritation. If fumes or combustion products are inhaled remove from contaminated area. Lay patient down. Keep warm and rested. Prostheses such as false teeth, which may block airway, should be removed, where possible, prior to initiating first aid Inhalation procedures. Apply artificial respiration if not breathing, preferably with a demand valve resuscitator, bag-valve mask device, or pocket mask as trained. Perform CPR if necessary. Transport to hospital, or doctor, without delay. IF SWALLOWED, REFER FOR MEDICAL ATTENTION, WHERE POSSIBLE, WITHOUT DELAY. For advice, contact a Poisons Information Centre or a doctor. Urgent hospital treatment is likely to be needed. In the mean time, qualified first-aid personnel should treat the patient following observation and employing supportive measures as indicated by the patient's condition. If the services of a medical officer or medical doctor are readily available, the patient should be placed in his/her care and a copy of the SDS should be provided. Further action will be the responsibility of the medical specialist. Ingestion If medical attention is not available on the worksite or surroundings send the patient to a hospital together with a copy of the SDS. Where medical attention is not immediately available or where the patient is more than 15 minutes from a hospital or unless instructed otherwise: INDUCE vomiting with fingers down the back of the throat, ONLY IF CONSCIOUS.
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