CURRICULUM VITAE

DANNY J. ZUEGE M.D., MSc. F.R.C.P.(C)

September 18, 2020 ------I. BIOGRAPHICAL DATA

Name: Danny Jeffery Zuege

Address: Intensive Care Unit Peter Lougheed Centre 3500 - 26th Avenue NE Calgary, Alberta, T1Y 6J4

E-mail: [email protected]

Telephone: (403) 943–4309 FAX: (403) 291–1491

Citizenship: Canadian

Present Rank: Clinical Professor of Medicine

Departments: Department of Critical Care Medicine (primary) Department of Medicine (Division of Respiratory Medicine) (secondary) Faculty: Cumming School of Medicine Institution: University of Calgary

Present Positions: Senior Medical Director Critical Care Strategic Clinical Network Alberta Health Services

Medical Informatics Lead – Critical Care Calgary Zone – Alberta Health Services

Co-chair – University of Calgary Medical Group Cumming School of Medicine University of Calgary

Intensivist Department of Critical Care Medicine Alberta Health Services/University of Calgary

Respirologist Department of Medicine Alberta Health Services/University of Calgary

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II. ACADEMIC RECORD

Final degree: MD, MSc, FRCP(C) Specialty: Internal Medicine Subspecialty: Critical Care Medicine, Respiratory Medicine Institution/City/Country: University of Alberta, University of Calgary Masters of Science (Respiratory Physiology) i. Undergraduate

Bachelor of Medical Science (With Distinction) 1988 University of Alberta ii. Special Professional

Doctor of Medicine (With Distinction) 1990 University of Alberta

Postgraduate Rotating Internship 1990 - 1991 Charles Camsell Provincial General Hospital Edmonton, Alberta

Internal Medicine Residency 1992 - 1995 Faculty of Medicine, University of Calgary

Pulmonary and Critical Care Medicine Fellowship 1995 - 1997 Faculty of Medicine, University of Calgary iii. Graduate and Post-doctoral

Post-doctoral Research Fellowship 1991 - 1992 Respiratory Research Group, University of Calgary

Masters of Science (Respiratory Physiology) 1994 University of Calgary iv. Licensure, Certification and Boards

Licentiate Medical Council of Canada 1990

Diplomat National Board of Medical Examiners 1991

General Licensure, College of Physicians and Surgeons of Alberta 1993 - Present

Diplomat American Board of Internal Medicine 1995

Fellow Royal College of Physicians and Surgeons of Canada 1995 - Present - Internal Medicine

Certification in Respiratory Medicine 1997 Royal College of Physicians and Surgeons of Canada

Certification in Pulmonary Diseases 1998 American Board of Internal Medicine

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Advanced Trauma Life Support (ATLS) Instructor 1998

Certification in Critical Care Medicine 1999 American Board of Internal Medicine

Certification in Critical Care Medicine 2002 Royal College of Physicians and Surgeons of Canada

Certificate - Leadership Strategies for Information 2013 Technology in Health Care Harvard School of Public Health

Certificate - Cumming School of Medicine Leadership Program 2018 Haskayne School of Business, University of Calgary

III. AWARDS AND DISTINCTIONS

Patient Experience Award – Delirium Initiative 2020 Health Quality Council of Alberta

Outstanding Clinician of the Year Award 2020 Department of Critical Care Medicine, University of Calgary

Service Award – eCritical Program Leadership 2019 Department of Critical Care Medicine

Presidents Excellence Award 2019 Outstanding Achievement in Innovation - Delirium Initiative Critical Care Strategic Clinical Network/eCritical Alberta Program Alberta Health Services

Rotating Resident Teaching Excellence Award 2018 Department of Critical Care Medicine, University of Calgary

Bronze Star Letter for Distinguished Service 2018 Respiratory Medicine Course Cumming School of Medicine, University of Calgary

Associate Dean’s Letter for Teaching 2018 Excellence - Undergraduate Curriculum Cumming School of Medicine, University of Calgary

Class of 2019 Honour Roll for Teaching Excellence 2018 Cumming School of Medicine, University of Calgary

Dean Sandham Critical Care Medicine Clinical Teaching Award 2017 Department of Critical Care Medicine, University of Calgary

Associate Dean’s Letter for Teaching Excellence 2016 - Undergraduate Curriculum Cumming School of Medicine, University of Calgary

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Bronze Star Letter for Distinguished Service 2016 Respiratory Medicine Course Cumming School of Medicine, University of Calgary

Presidents Excellence Award 2016 Outstanding Achievement in Innovation eCritical Alberta Program, Alberta Health Services (Finalist)

LEADing Practice Initiative Award 2016 (Spectrum Calgary application) As part of the Spectrum Development Group Canada Health Infoway and Accreditation Canada

Class of 2017 Honour Roll for Teaching Excellence 2016 Cumming School of Medicine, University of Calgary

Associate Dean’s Letter for Teaching Excellence 2015 - Undergraduate Curriculum Cumming School of Medicine, University of Calgary

Bronze Star Letter for Excellence in Teaching 2015 Respiratory Medicine Course Cumming School of Medicine, University of Calgary

Associate Dean’s Letter for Teaching Excellence 2014 - Undergraduate Curriculum Cumming School of Medicine, University of Calgary

Bronze Star Letter for Excellence in Teaching 2014 Respiratory Medicine Course Cumming School of Medicine, University of Calgary

Innovation in the Adoption of Health Informatics Award 2007 VAP Surveillance System Canadian Health Informatics Association (COACH)

Physician of Merit Award 2006 Calgary General Hospital Medical Staff Association

Dean Sandham Critical Care Medicine Clinical Teaching Award 2003 Department of Critical Care Medicine, University of Calgary

Award for Outstanding Resident Teaching 2002 (“Silver Finger” Award) Department of Medicine, University of Calgary

Fellow American College of Chest Physicians 1999

Associate Dean’s Letter for Teaching Excellence 1997 - Undergraduate Curriculum Faculty of Medicine, University of Calgary

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Gold Star Letter for Excellence in Teaching 1997 Respiratory Medicine Course Faculty of Medicine, University of Calgary

Fellow Royal College of Physicians and Surgeons of Canada 1995

Canadian Thoracic Society Best Scientific Abstract Award 1992 (Royal College Presentation)

Post-doctoral Research Fellowship 1991 Heart and Stroke Foundation of Canada

Post-doctoral Research Fellowship 1991 Alberta Heritage Foundation for Medical Research (Declined)

Hewlett Packard Top Medical Graduate Award 1990

Sandoz Prize in Medicine 1990

C.V. Mosby Book Award 1990

Louise McKinney Post-Secondary Scholarship's 1986, 1987, 1988, 1989

University of Alberta Board of Governers Prize in Medicine 1988

Alberta Heritage Foundation for Medical Research Summer Studentship 1988

A.W. Downs Prize in Physiology 1987

Alberta Heritage Foundation for Medical Research Summer Studentship 1986

Dr. A.J. Pauly Bursary in Medicine 1986

Paul Edward Macleod Memorial Prize in Chemistry 1986

Viscount Bennett Scholarship for Academic Achievement 1985

IV. ACADEMIC AND MEDICAL LEADERSHIP APPOINTMENTS

Clinical Professor 2013 - Present Departments of Medicine and Critical Care Medicine Cumming School of Medicine, University of Calgary

Senior Medical Director 2019 – Present Critical Care Strategic Clinical Network Alberta Health Services

Medical Director 2011 - 2019 eCritical Provincial Critical Care Clinical Information System Program Alberta Health Services

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Clinical Associate Professor 2006 - 2013 Departments of Medicine and Critical Care Medicine Faculty of Medicine, University of Calgary

Medical Director – Southern Alberta Organ and Tissue 2007 - 2010 Donation Program Alberta Health Services

Medical Director – Southern Alberta HOPE (Human Organ 2003 - 2007 Procurement and Exchange) Program Calgary Health Region

Medical Director – Critical Care Unit 2001 - 2012 Peter Lougheed Hospital, Calgary Health Region

Clinical Assistant Professor 1997 - 2006 Departments of Medicine and Critical Care Medicine Faculty of Medicine, University of Calgary

V. EDUCATIONAL ACTIVITIES i. Undergraduate

Cardiorespiratory System Course (MDCN 307) 2001 - Present Small Group Teaching Emergencies, Shock, Respiratory Failure, Pleural Diseases, Obstructive Diseases, Pulmonary Vascular Diseases, Infections Cumming School of Medicine, University of Calgary (~8 hours/year)

ICU Rotation Preceptor 2000 - Present Clinical Clerk Critical Care Rotations Cumming School of Medicine, University of Calgary (~14 weeks/year)

Pulmonary Rotation Preceptor 2000 - Present Clinical Clerk Pulmonary Medicine Rotations Cumming School of Medicine, University of Calgary (~3 weeks/year)

Cardiorespiratory System Course (MDCN 307) 1996 - Present Clinical Skills Preceptor Cumming School of Medicine, University of Calgary (~10 hours/year)

Medicine 440 Elective Preceptor 2018 (Critical Care Medicine) Cumming School of Medicine, University of Calgary (~40 hours)

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Advanced Respiratory Therapy Course (RESP 365) – Lecturer 2002 - 2008 Acute Respiratory Distress Syndrome Respiratory Therapy Program, SAIT (~4 hours/year)

Medicine 440 Elective Preceptor 2002 - 2003 (Pulmonary/Critical Care Medicine) Faculty of Medicine, University of Calgary (~40 hours)

Medicine 440 Elective Preceptor 2000 - 2001 (Pulmonary/Critical Care Medicine) Faculty of Medicine, University of Calgary (~40 hours)

Surface Anatomy teaching - First year medical students 2000 Faculty of Medicine, University of Calgary (~3 hours)

Faculty Advisor – first year medical student 1999 – 2002 Faculty of Medicine, University of Calgary

Respiratory System Course (MDCN 307) Lecturer 1999 – 2000 Hemoptysis; Pulmonary Thromboembolism Faculty of Medicine, University of Calgary (~6 hours/year)

LMCC Pulmonary Review Course Lecturer 1999 Faculty of Medicine, University of Calgary (~5 hours)

Respiratory System Course (MDCN 307) Cube Manager 1998 - 2000 Pulmonary Circulation Faculty of Medicine, University of Calgary (~20 hours/year)

Respiratory System Course (MDCN 307) Lecturer 1997 - 2000 Hypoxia and Gas Transport Faculty of Medicine, University of Calgary (~2 hours/year)

Medical Student Physical Examination Course Instructor 1997 - 1999 Faculty of Medicine, University of Calgary (~20 hours/year)

Medical Student Clinical Skills OSCE Examiner 1997 Faculty of Medicine, University of Calgary (~3 hours)

Respiratory System Course (MDCN 307) Small Group Teaching 1996 - 2000 Blood Gases Faculty of Medicine, University of Calgary (~10 hours/year)

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ii. Graduate

External Examiner – PhD Thesis Oral Exam 2020 Sayed Metwaly Metabolomics study of ARDS diagnosis, heterogeneity and mortality Department of Critical Care Medicine Cumming School of Medicine, University of Calgary

Member – MSc/PhD Supervisory Committee 2014 – Present Dr. Giovanni Taglibue Thesis: Parasternal intercostals and costal diaphragm muscle function during C02 stimulation Department of Critical Care Medicine Cumming School of Medicine, University of Calgary

Advanced Critical Care Physiology Course (MDSC 623.03) Lecturer 2016 - Present (Respiratory Mechanics – Static and Dynamic) Cumming School of Medicine, University of Calgary (~12 hours/year)

Co-sponsor – Capstone Project 2016 – 2017 Ms. Karla Avery Masters of Arts (Health Leadership) Program, Royal Roads University

Member – MSc Supervisory Committee 2015 – 2018 Ms. Jamie Boyd Thesis: ICU discharge risk stratification tools (Successful thesis defense examination) Department of Community Health Sciences Cumming School of Medicine, University of Calgary

Member – MSc Supervisory Committee 2015 – 2017 Dr. Jason Lord Thesis: Central Line Insertion Education (Successful thesis defense examination) Department of Community Health Sciences Cumming School of Medicine, University of Calgary

Research Supervisor 2014 – 2017 Dr. Daniel Vis, Internal Medicine Resident Research Topic: Incidence and etiology of non-infectious ventilator associated events in invasively ventilated adult critical care patients in Calgary Internal Medicine Program, University of Calgary Best Poster Award (Health Services Research) at Department of Medicine Resident Research Day, Calgary, May 2017.

Member – MSc Supervisory Committee 2011 – 2014 Dr. Vikas Chaubey Thesis: Is the mortality from community-onset bacteremia associated with sepsis and septic shock changing over time? A Population-based analysis of secular trends in community-onset bacteremia in patients admitted to the intensive care unit Departments of Critical Care Medicine and Community Health Sciences Faculty of Medicine, University of Calgary

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Member – Research Project Committee 2010 – 2014 Ms. Tracy Chin Project Topic: Assessment of Antibiotic Use in patients who develop Ventilator Associated Pneumonia in Alberta Health Services-Calgary Zone Pharmacy Department, Alberta Health Services – Calgary Zone

Member - MSc Supervisory Committee 2010 – 2013 Ms. Kathryn Linton Thesis: The impact of ventilator-associated pneumonia among pre-hospital intubated patients (Successful thesis defense examination) Department of Community Health Sciences Faculty of Medicine, University of Calgary

External Member - MSc Supervisory Committee 2007 – 2010 Mr. Reza Shahpori Thesis: ICU Telehealth and remote monitoring (Tele-ICU) is there a need? (Successful thesis defense examination) School of Health Information Science, University of Victoria Department of Community Health Sciences Faculty of Medicine, University of Calgary

Research Supervisor 2007 - 2010 Dr. Gurmeet Singh, Critical Care Fellow Research Topic: Internal Jugular Vein Ultrasound Measures and Fluid Responsiveness in Post-Operative Cardiac Surgical Patients Critical Care Program, University of Calgary

Member – Research Project Committee 2003 - 2005 Ms. Candace Cameron Quetiapine for the management of delirium in the critically ill Pharmacy Department, Calgary Health Region

Lecturer – Nursing 572 Advanced Practicum – Critical Care 2003 - 2006 (ARDS) Faculty of Nursing, University of Calgary (~3 hours/year)

Lecturer - Advanced Respiratory Physiology Course (MDSC 623.02) 2001 - 2013 (Mechanical Ventilation – Measurements and Monitoring) Faculty of Medicine, University of Calgary (~4 hours/year)

Lecturer - Advanced Respiratory Physiology Course (MDSC 623.01) 1996 - 2013 (Lung Fluid Balance and Pulmonary Edema) Faculty of Medicine, University of Calgary (~5 hours/year)

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iii. Postgraduate

Prospective Resident Evaluation 2019 - Present CARMS Application Process Critical Care Medicine Program, University of Calgary (~4 hours/year)

Presenter – Clinic pathologic Correlation Rounds 2018 - Present Critical Care Program, University of Calgary (~6 hours/year)

Lecturer – Critical Care fellows academic half-day 2018 - Present (Ventilators I – Basics of Mechanical Ventilation) Critical Care Program, University of Calgary (~4 hours/year)

Preceptor – Rotating Resident Crash Course and 2018 - Present Crisis Simulation Sessions Critical Care Program, University of Calgary (~8 hours/year)

Lecturer – Pulmonary fellows academic half-day 2018 – Present (Respiratory Mechanics I and II) Respiratory Program, University of Calgary (~8 hours/year)

Prospective Resident Evaluation 2017 - Present CARMS Application Process Respiratory Medicine Program, University of Calgary (~4 hours/year)

Lecturer – Critical Care fellows academic half-day 2017 - Present (Acute Infections Causing Respiratory Failure) Critical Care Program, University of Calgary (~4 hours/year)

Lecturer – Critical Care fellows academic half-day 2016 - Present (Interstitial Lung Diseases in Critical Care) Critical Care Program, University of Calgary (~4 hours/year)

Preceptor – Grand Rounds Resident Presentations 2015 – Present Critical Care Program, University of Calgary (~3 hours/year)

Instructor – Difficult Airway Management Course 2013 – Present Department of Critical Care Medicine, Alberta Health Services (~8 hours/year)

Lecturer – Critical Care Rotating Residents Rounds 2007 - Present (Various Topics) Cumming School of Medicine, University of Calgary (~8 hours/year)

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Preceptor – Lung Physiology Sessions 2006 - Present Pulmonary Fellows PFT Lab Rotations Respiratory Program, University of Calgary (~4 hours/year)

Examiner - Pulmonary Fellows Practice Exams 2000 - Present Pulmonary Program, University of Calgary (~4 hours/year)

Preceptor – Internal Medicine MTU Teaching Sessions 2000 – Present (Respiratory Medicine and Chest Radiology) Peter Lougheed Hospital Internal Medicine Program, Department of Medicine, University of Calgary (~2 hours/year)

Ward Preceptor - Respiratory Medicine Rotation 1997 - Present Internal Medicine Program, Department of Medicine, University of Calgary (~3 weeks/year)

Pulmonary Outpatient Clinic Preceptor 1997 - Present Respiratory Medicine Rotation Internal Medicine Program, Department of Medicine, University of Calgary (~15 hours/year)

ICU Preceptor - Critical Care Rotations 1997 - Present Rotating residents and critical care residents Critical Care Program, University of Calgary (~14 weeks/year)

Lecturer – Pulmonary fellows academic half-day 2017 (Respiratory Mechanics III) Respiratory Program, University of Calgary (~4 hours)

Faculty Mentor – Critical Care Medicine Resident 2016 - 2018 Critical Care Program, University of Calgary

Faculty Mentor – Critical Care Medicine Resident 2014 - 2016 Critical Care Program, University of Calgary

Lecturer – Critical Care fellows academic half-day 2014, 2018, 2020 (Neurologic Death) Critical Care Program, University of Calgary (~4 hours/year)

Lecturer – Critical Care Fellows academic half-day 2014 (CLABSI) Critical Care Program, University of Calgary (~4 hours)

Lecturer – Pulmonary fellows academic half-day 2012 – 2017 (Principles and Physiology of Mechanical Ventilation) Respiratory Program, University of Calgary (~4 hours/year)

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Lecturer – Critical Care fellows academic half-day 2012, 2013, 2015, 2016, 2019 (Infection Control in ICU) Critical Care Program, University of Calgary (~4 hours/year)

Lecturer – Critical Care fellows academic half-day 2011, 2020 (Neurologic Death/Organ Donor Management) Critical Care Program, University of Calgary (~4 hours)

Lecturer – Critical Care Fellows academic half-day 2011, 2013, 2015, 2017 - 2020 (VAP and CLBSI) Critical Care Program, University of Calgary (~4 hours/year)

Preceptor – Critical Care Fellows simulation session 2010 (Crisis simulation) Critical Care Program, University of Calgary (~2 hours)

Lecturer – Critical Care fellows academic half-day 2008 (Principles of ICU Design) Critical Care Program, University of Calgary (~4 hours)

Research Supervisor 2007 - 2010 Dr. Gurmeet Singh, Critical Care Fellow Research Topic: Internal Jugular Vein Ultrasound Measures and Fluid Responsiveness in Post-Operative Cardiac Surgical Patients Critical Care Program, University of Calgary (~120 hours)

Lecturer – Critical Care Fellows academic half-day 2006 – 2013 (Advanced Mechanical Ventilation/Cardiopulmonary Interaction) Critical Care Program, University of Calgary (~4 hours/year)

Lecturer – Critical Care Fellows academic half-day 2006 – 2013, 2016 - 2020 (Complications of Transplantation) Critical Care Program, University of Calgary (~4 hours/year)

Lecturer – Critical Care Fellows academic half-day 2003 - 2011 (Lung Transplantation) Critical Care Program, University of Calgary (~4 hours/year)

Lecturer – CanMeds 2000 Course 2003 (Academic Career Paths) Department of Medicine, University of Calgary (~4 hours)

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Basic Modular Workshop (Examination skills workshop) 2002 Royal College of Physicians and Surgeons Canada

Member – Examination Board – Respiratory Medicine 2001 - 2006 Royal College of Physicians and Surgeons Canada

Lecturer – Critical Care Rotating Residents Rounds 2001 - 2007 (Ventilation and Ventilators) Faculty of Medicine, University of Calgary (~10 hours/year)

Prospective Resident Evaluation 2000-2009, 2012, 2020 CARMS Application Process Critical Care Program, University of Calgary (~4 hours/year)

Examiner - Pulmonary Fellows OSCE and Oral Exams 2000 - 2017 Respiratory Program, University of Calgary (~3 hours/year)

Lecturer – Pulmonary Fellows academic half-day 2000 – 2011 (Lung Transplantation) Pulmonary Program, University of Calgary (~4 hours/year)

Examiner – Critical Care Medicine Fellows OSCE and oral exams 2000 - 2002 Critical Care Program, University of Calgary (~3 hours/year)

Examiner - R4 Internal Medicine Practice Exams 1999 – 2003 Internal Medicine Program, Department of Medicine, University of Calgary (~5 hours/year)

Instructor – Advanced Trauma Life Support Course 1998 – 2003

Lecturer – ICU Residents Introductory Course 1998 – 2003 (Respiratory Failure) Critical Care Program, University of Calgary (~10 hours/year)

Examiner – R3 Internal Medicine Oral Exams 1997 - 2002 Internal Medicine Program Department of Medicine, University of Calgary (~3 hours/year)

iv. Continuing Medical Education

Calgary Critical Care Nurses Group 2018 Fall Update Presenter Critical Care Informatics/Connect Care (~2 hours)

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Instructor – Difficult Airway Management Course 2013 – Present Department of Critical Care Medicine, Alberta Health Services (~8 hours/year)

Presenter – Grand Rounds 1997 - Present Critical Care Medicine (~10 hours/year)

Presenter – Journal Clubs 1997 - Present Pulmonary and Critical Care Medicine (~6 hours/year)

Morbidity & Mortality Conferences 1997 - Present Case Review and Presenter Peter Lougheed and Foothills Hospitals, Department of Critical Care Medicine (~40 hours/year)

Physician Training for eCritical System 2011 - 2019 Developed physician training materials for eCritical Provincial Critical Care Clinical Information System (written and electronic physician manuals; case-based training guides; training cases). Distinct materials and training for adult and cardiac configurations and user groups. Guided the content, organization and testing of a eLearning tool for physician training. Led the implementation of physician training. Alberta Health Services (~275 hours)

Presenter - Rural Emergency Medicine Course 2007 Organ and Tissue Donation for Rural Practitioners Banff, Alberta (~4 hours)

Program Development and Delivery 2003 - 2010 Organ and Tissue Donation education. Development of various physician educational materials related to organ and tissue donation (adult and pediatric ordersets; program website with educational tools; guidelines for donor assessment and medical management). Delivery of organ and tissue donation education via various means to various physician and non-physician groups throughout Southern Alberta. Calgary Health Region and Alberta Health Services (~40 hours/year)

Radiology Rounds Presenter 2000 - 2002 Various Chest Radiology topics Peter Lougheed Hospital (~8 hours/year)

Presenter - Medical Grand Rounds 1997 - 2005 Peter Lougheed Hospital, Department of Medicine

Rural Regional Conference Series Presenter 1998 Blood Gas Analysis

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Vulcan, Alberta (~4 hours)

Calgary Critical Care Nurses Group - Evening Seminar Series Lecturer 1997 - 2000 Various Critical Care Medicine topics (~8 hours/year)

VI. ADMINISTRATIVE RESPONSIBILITIES i. Departmental

Co-chair - Equity, Diversity and Inclusion Committee 2020 – Present Department of Critical Care Medicine

Chair - Medical Leader Performance Review Committee 2019 Department of Critical Care Medicine

Senior Faculty Mentor 2018 – Present For junior faculty member and new leader Department of Critical Care Medicine

Member – ICU Research Executive Committee 2003 - Present Department of Critical Care Medicine

Guideline Development and Implementation 2011 - 2012 Chlorhexidine-impregnated Central Line Dressings Department of Critical Care Medicine

Guideline Development and Implementation 2010 - 2011 Management of the Critically ill ILI Patient Department of Critical Care Medicine

Member – FMC ICU Medical Director Search 2010 and Selection Committee

Member – Respirology Clinical Competence Guidelines Group 2010 - 2011 Division of Respiratory Medicine, Department of Medicine

Member – Pandemic Planning Group 2009 - 2011 Department of Critical Care Medicine

Co-chair – Infection Prevention Program 2008 – 2011 Department of Critical Care Medicine

Member – Quality and Safety Improvement Committee 2008 – 2012 Department of Critical Care Medicine

ICU Clinical Information System Replacement Project 2007 - 2009 RFP Development, Evaluation and Vendor Selection Department of Critical Care Medicine and Advanced Technologies – Calgary Health Region

Co-chair – Quality Committee 2007 – 2012 Peter Lougheed Hospital ICU, Department of Critical Care Medicine

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Member – ICU Clinical Information System 2006 – 2010 Replacement/eICU Project Department of Critical Care Medicine

Co-chair – Central Lines Working Group 2006 – 2008 Department of Critical Care Medicine

Co-chair – PLC ICU Outreach Committee 2006 – 2010 Peter Lougheed Hospital ICU, Department of Critical Care Medicine

Member – Patient Care Information System (PCIS) Unit Council 2006 – 2008 Peter Lougheed Hospital ICU, Department of Critical Care Medicine

Member – Medical Executive Committee 2005 – 2012 Department of Critical Care Medicine

Member – Patient Care Information System (PCIS) 2005 – 2009 Clinical Working Group Department of Critical Care Medicine

Member – ICU Outreach Program Steering Committee 2005 – 2010 Department of Critical Care Medicine

Member – Cross-site ICU Planning Committee 2005 – 2010 Department of Critical Care Medicine

Reviewer – Critical Incident Reviews 2005, 2007 Clinical Safety and Quality Assurance Council Department of Critical Care Medicine

Member – Patient Care Information System 2004 - 2009 Critical Care Order Set Working Group Department of Critical Care Medicine

Member – Central Line Procedures Quality Improvement 2004 - 2006 Working Group Department of Critical Care Medicine

Member – PLC ICU Capital Expansion Project 2004 – 2010 Department of Critical Care Medicine

Member – Critical Care TRACER Database Redevelopment Project 2004 – 2011 Department of Critical Care Medicine

Chair – Ventilator Associated Pneumonia Committee 2004 - 2009 Canadian Critical Care Safety Collaborative and Department of Critical Care Medicine

Ventilator Associated Pneumonia Database Development 2003 – 2013 Department of Critical Care Medicine

Member - Ventilator Associated Pneumonia Surveillance Team 2003 – 2011 Department of Critical Care Medicine and Calgary Health Region Infection Control Program

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Critical Care Central Line Infection Surveillance Program Development 2003 - 2011 Department of Critical Care Medicine

Guideline Development – Recombinant Activated Protein C use in 2002 - 2003 Severe Sepsis Department of Critical Care Medicine

Member – ‘Daily Goals’ Working Group 2002 - 2005 Department of Critical Care Medicine

Site Research Leader 2001 - 2014 Peter Lougheed Hospital, Department of Critical Care Medicine

Member – Accreditation 2002 Committee 2001 – 2003 Department of Critical Care Medicine

Member – ICU Executive Committee 2001 - 2012 Department of Critical Care Medicine

Member – ICU Recruitment Committee 2001 - 2005 Department of Critical Care Medicine

Member – ICU Residency Training Program Committee 2001 – 2004 Department of Critical Care Medicine

Medical Director – Critical Care Unit 2001 - 2012 Peter Lougheed Hospital, Department of Critical Care Medicine

Chair - Regional Critical Care DVT Prophylaxis 2000 - 2007 Quality Improvement Committee Department of Critical Care Medicine

Member – Mechanical Ventilation Protocols Quality 2000 - 2005 Improvement Committee Department of Critical Care Medicine

Member – Peter Lougheed Hospital Department 2000 of Medicine Site Chief Search Committee

Member – TRACER Database Renewal Group 1998 – 2000 Department of Critical Care Medicine

Coordinator – TRACER/Morbidity Review 1998 - 2012 Peter Lougheed Hospital, Department of Critical Care Medicine

Member – Ventilator Associated Pneumonia Study Group 1997 - 2003 Department of Critical Care Medicine

Chair - Critical Care Morbidity and Mortality Review Committee 1997 - 2012 Peter Lougheed Hospital, Department of Critical Care Medicine

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ii. Faculty of Medicine

Co-chair – Helios/UCMG Scholarship Committee 2018 – Present Cumming School of Medicine

Critical Care Department Head Search and Selection 2018 Ad Hoc Interviews University of Calgary and Alberta Health Services – Calgary Zone

Chair – Out of Country Billing Procedures Review Group 2018 - Present University of Calgary Medical Group Executive Council Cumming School of Medicine

Co-chair - Executive Council 2016 - Present University of Calgary Medical Group, Cumming School of Medicine

Member – Billing Procedures Review Group 2016 - Present University of Calgary Medical Group Executive Council Cumming School of Medicine

Member – Advisory Committee 2014 - Present TVN Grant - Developing an Evidenced-Informed Intensive Care Unit Discharge Toolkit University of Calgary and Alberta Health Services

Member – Steering Committee 2014 - Present PRIHS Grant - Identifying and Evaluating Intensive Care Unit Capacity Strain in Alberta University of Calgary and Alberta Health Services

Scientific Reviewer 2009 - Present Conjoint Health Research Ethics Board Cumming School of Medicine, University of Calgary

Member – Advisory Committee 2014 - 2018 PRIHS Grant - Reassessing Practices in the Daily Care of Critically Ill Patients: Building Capacity and Methodology to Identify & Close Evidence-Care Gaps University of Calgary and Alberta Health Services

Critical Care Department Head Search and Selection 2013 Ad Hoc Interviews University of Calgary and Alberta Health Services – Calgary Zone

Member - Professional Development Fund Guidelines Working Group 2010 – 2012, 2020 University of Calgary Medical Group Executive Council Faculty of Medicine

Video Development 2008 Title: Practically Speaking - Hand Hygiene for Medical Students Calgary Health Region (Infection Control Program) and Faculty of Medicine, University of Calgary

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Member – Regional Critical Care Department Head 2007 – 2008 Review Committee University of Calgary and Calgary Health Region

Member - University of Calgary Medical Group Executive Council 2007 - 2017 Department of Critical Care Medicine representative Cumming School of Medicine

Department Leader – Regional Critical Care Department Head 2002 – 2003 Search and Selection Committee University of Calgary and Calgary Health Region

Member - University of Calgary Medical Group Executive Council 2000 - 2007 PLC hospital representative Faculty of Medicine

University of Calgary Medical Group Executive Council 1998 - 2000 Alternate PLC hospital representative Faculty of Medicine

Adjunct Member – Faculty Council 1998 - 2001 Faculty of Medicine, University of Calgary

iv. Regional Health Authority

Co-Chair – ARIO Clinical Services Review Group 2020 – Present (ICU Discharge Delay) Alberta Health Services

Member – ARIO Clinical Services Review Group 2020 – Present (Organ Donation) Alberta Health Services

Member - Critical Care Accreditation Provincial Review Committee 2020 – Present Alberta Health Services/Accreditation Canada

Co-Chair – Provincial Critical Care Pandemic Coordinating 2020 – Present Committee Alberta Health Services

Co-Chair – Provincial Emergency Coordinating Centre 2020 – Present Critical Care Leadership Group Alberta Health Services

Chair – Provincial Critical Care Medical Leadership 2020 – Present Pandemic Planning Group Alberta Health Services

Member – Provincial Pandemic Critical Care Triage Working Group 2020 – Present Alberta Health Services

Member – COVID Pandemic Manufactured Ventilator Collaborative 2020 – Present Working Group Alberta Health Services

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Secondary Reviewer – Pandemic Scientific Advisory Group 2020 – Present Various review projects Alberta Health Services

Member – Various COVID-19 Pandemic Working Groups 2020 – Present (Critical Care Drug Supply Group; Pediatric Critical Care COVID-19 Sub-group; Respiratory Management Pathway Working Group; Provincial Pandemic ECLS Working Group) Alberta Health Services

Member – Critical Care Machine Learning Project 2019 – Present Critical Care Strategic Clinical Network Alberta Health Services

Senior Medical Director 2019 – Present Critical Care Strategic Clinical Network Alberta Health Services

Member – Strategic Clinical Network Leadership 2019 – Present Alberta Health Services

Co-Chair – Critical Care Strategic Clinical Network Core Committee 2019 – Present Alberta Health Services

Member – Critical Care Strategic Clinical Network 2019 – Present Pediatric Operations Liaison Committee Alberta Health Services

Co-Chair – Provincial Delirium Committee 2019 – Present Critical Care Strategic Clinical Network

Member – Albumin De-adoption in ICU Project Steering Committee 2019 – Present Critical Care Strategic Clinical Network Alberta Health Services

Member – Transitions in Care Steering Committee 2019 – Present Critical Care Strategic Clinical Network Alberta Health Services

Member – Transitions in Care Working Group 2019 – Present Critical Care Strategic Clinical Network Alberta Health Services

Member – Early Warning Scores Working Group 2019 – Present Connect Care Program, Alberta Health Services

Member – Predictive Analytics Working Group 2018 – Present Connect Care Program, Alberta Health Services

Co-chair – Connect Care Provincial Critical Care Area Council 2018 - Present Alberta Health Services

Medical Informatics Lead – Critical Care 2018 - Present Calgary Zone, Alberta Health Services

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Co-chair – Adult Subgroup of the Connect Care Provincial 2018 - Present Critical Care Area Council Alberta Health Services

Member – Pediatric and Neonatal Subgroups of the Connect 2018 - Present Care Provincial Critical Care Area Council Alberta Health Services

Member – eCritical TRACER Sub-Committees 2017 – Present (Adult, Pediatric, Cardiac and Neonatal committees) eCritical Provincial Critical Care Clinical Information System Program Alberta Health Services

Member – Critical Care Strategic Clinical Network 2016 – Present Adult Operations Liaison Committee Alberta Health Services

Program Development - Key Performance Indicators 2015 - Present Critical Care Strategic Clinical Network Alberta Health Services

Member – eCritical TRACER Steering Committee 2013 – Present eCritical Provincial Critical Care Clinical Information System Program Alberta Health Services

Member – eCritical TRACER Working Group 2013 – Present eCritical Provincial Critical Care Clinical Information System Program Alberta Health Services

Reviewer – Delirium Clinical Practice Guidelines 2017 – 2019 Critical Care Strategic Clinical Network Alberta Health Services

Member – eCritical Provincial NICU Advisory Committee 2016 – 2019 eCritical Provincial Critical Care Clinical Information System Program Alberta Health Services

Member – Provincial Critical Care Information Systems 2014 – 2017 Strategic Working Group/RFP Development Group Alberta Health Services

Co-Chair - Donation after Cardio-circulatory Death (DCD) 2013 - 2018 Working Group Calgary Zone, Alberta Health Services

Reviewer - Complex Quality Assurance Review Committee 2012 Quality Assurance Program, Alberta Health Services

Member – Critical Care Strategic Clinical Network Core Committee 2012 – 2019 Alberta Health Services

Medical Director 2011 – 2019 eCritical Provincial Critical Care Clinical Information System Program Alberta Health Services

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Member – Executive Leadership Team 2010 – 2019 eCritical Critical Care Clinical Information System Project Alberta Health Services

Co-chair – Provincial Advisory Group 2010 – 2014 eCritical Critical Care Clinical Information System Project Alberta Health Services

Member – Alberta Critical Care Network Steering Committee 2010 – 2012 Alberta Health Services

Co-chair – Clinical Informatics Council 2010 – 2012 Alberta Critical Care Network, Alberta Health Services

Advanced ICU Alarm and Event Management System Project 2009 - 2012 Proposal and RFP Development; Vendor Evaluation and Selection; Contract Negotiation and Implementation Alberta Health Services

Member – eCritical Program Clinical Design Team 2009 – 2014 Alberta Health Services

Reviewer – Extraordinary Therapeutic Requests 2009 Calgary Zone Pharmacy and Therapeutics Committee Alberta Health Services

Co-chair – ECLS Use in H1N1 Disease Expert Advisory Committee 2009 Alberta Health Services

Co-chair – Emergent Services Clinical Safety Committee 2008 - 2009 Calgary Health Region

Video Development 2008 Title: Practically Speaking - Hand Hygiene for Medical Students Calgary Health Region (Infection Control Program) and Faculty of Medicine, University of Calgary

Medical Director – Southern Alberta Organ and Tissue 2007 - 2010 Donation Program Calgary Health Region

Program Development – Alberta Provincial Organ 2006 – 2010 and Tissue Donation Program Calgary Health Region

Co-Chair – HOPE (Human Organ Procurement and Exchange) 2005 – 2007 Program Accreditation 2006 Committee Canadian Council on Health Services Accreditation Process HOPE Program, Calgary Health Region

Member – Thromboembolism Diagnostic Algorithm Panel 2005 - 2007 Calgary Health Region

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Member – Regional Anticoagulation Guidelines Content 2005 - 2009 Development Team Calgary Health Region

Member – Regional Integrated Ventilation Program Advisory Committee 2005 - 2009 Calgary Health Region

Member – Sunrise Clinical Manager PCIS Testing Group 2004 - 2011 Calgary Health Region

Co-Chair – Southern Alberta HOPE Advisory Committee 2004 - 2010 Calgary Health Region

Chair – HOPE Organ Quality Assurance Committee 2004 - 2010 Calgary Health Region

Member – Joint HOPE/Tissue Committee 2003 - 2010 Calgary Health Region

Medical Director – HOPE Program 2003 - 2007 Calgary Health Region

Department Leader – Regional Critical Care Department Head 2002 - 2003 Search and Selection Committee University of Calgary and Calgary Health Region

Medical Director – Critical Care Unit 2001 - 2012 Peter Lougheed Hospital

Member – Regional Adult Pharmacy and Therapeutics Committee 2000 - 2011 Calgary Health Region

Reviewer – Regional Critical Incident Review Committee 2000 Calgary Health Region

Consultant – Calgary Regional Health Authority 1997 - 1998 Bow Valley Centre Employee Asbestos Survey

v. Hospital

Program Development - PLC Simulation Centre 2010 – 2014 Proposal development; Acquisition of funding; Detailed design and planning consultation; Implementation Peter Lougheed Hospital/Calgary Health Trust

Member – PLC Site Council 2001 - 2012 Peter Lougheed Hospital

Danny J. Zuege September 18, 2020 Page 23 of 48

VII. PROFESSIONAL ACTIVITIES i. Membership in Professional and Learned Societies

Fellow: Royal College of Physicians and Surgeons of Canada 1995 - Present American College of Chest Physicians 1999 - Present

Member: Alberta Medical Association 1990 - Present American Thoracic Society 1995 - Present Alberta Lung Association 1997 - Present Canadian Critical Care Society 1997 - Present Alberta Society of Intensive Care Physicians 1997 - Present Canadian Thoracic Society 1997 - Present Society of Critical Care Medicine 1998 - Present COACH Canada Health Informatics Association 2013 - Present National Institutes of Health Informatics 2015 - Present American College of Physicians 1997 - 2010 Canadian Association of Transplantation 2006 - 2010

ii. Professional Service

Grant Review

Reviewer – Research Grant Competition 2020 PSI Foundation (Ontario)

Reviewer – Research Grant Competition 2020 Canadian Frailty Network

Reviewer – Seed Grant Competition 2019 Critical Care Strategic Clinical Network, Alberta Health Services

Fellowship Grant Reviewer 2018 Medical Research Council (UK)

Reviewer - DCCM Research Competition 2010 Department of Critical Care Medicine

External Grant Reviewer - Max Bell Foundation 2007 Medical Research Grant Competition

Journal Reviewer

Canadian Journal of Anesthesia Biomed Research International European Journal of Clinical Microbiology and Infectious Diseases Diagnostic Microbiology & Infectious Disease BMC Health Services Research JPEN Clinical and Investigative Medicine British Journal of Medicine and Medical Research Case Reports in Medicine

Danny J. Zuege September 18, 2020 Page 24 of 48

Editorial Boards

Member - Editorial Advisory Board 2013 - 2015 Open Access Critical Care

National and International Committees

Member - National Stakeholder Consultation on Organ and Tissue 2008 Donation and Transplantation In Canada Canadian Blood Services

Member – Organ Donation Collaborative Expert Advisory Committee 2006 Canadian Council for Donation and Transplantation

Member – Canadian Ventilator Associated Pneumonia 2005 - 2008 Consensus Guideline Working Group Canadian Critical Care Trials Group

Member – Donation After Cardiocirculatory Death Forum 2005 Canadian Council for Donation and Transplantation

Member – Ventilator Associated Pneumonia Committee 2004 - 2009 Canadian Critical Care Safety Collaborative

Government Agencies

Member – Provincial Stakeholder Consultation on Revised Legislation 2013 (Bill 207) Human Tissue and Organ Donation Amendment Act Ministry of Health, Government of Alberta

Member - Rapid HIV Testing Pilot Program 2008 - 2010 Health and Wellness, Government of Alberta

Physician Donation Leader for Southern Alberta 2003 - 2006 Health and Wellness, Government of Alberta

Member – Provincial SARS Advisory Committee 2003 - 2004 Health and Wellness, Government of Alberta

Chair – Provincial Brain Death Advisory Panel 2003 Health and Wellness, Government of Alberta

Member – Provincial Organ and Tissue Donation and 2002 - 2009 Transplantation Advisory Committee Health and Wellness, Government of Alberta

Pulmonary Medicine Representative 1999 - 2001 Alberta Relative Value Guide Commission Health and Wellness, Government of Alberta and Alberta Medical Association

Danny J. Zuege September 18, 2020 Page 25 of 48

Other

Member – Competence Committee 2016 - Present College of Physicians and Surgeons of Alberta

Scientific Reviewer 2009 - Present Conjoint Health Research Ethics Board Cumming School of Medicine, University of Calgary

Board Member – Canadian Intensive Care Foundation 2003 - 2009 (Calgary Chapter)

Member – Celebrate Life Event Planning Committee 2001 - 2008 Canadian Intensive Care Foundation (Calgary Chapter)

Courses Attended

Good Clinical Practice for Clinical Research 2020 Canada Refresher course CITI-Canada Collaborative Institutional Training Initiative AIHS Alberta Clinical Research Consortium

PROSCI Change Management Course 2018 Alberta Health Services

EPIC Overview Course 2018 Alberta Health Services/EPIC Corporation

Haskayne/Cumming School of Medicine Leadership Program 2017 - 2018 University of Calgary

Good Clinical Practice for Clinical Research 2017 Level 1 - Basic CITI-Canada Collaborative Institutional Training Initiative AIHS Alberta Clinical Research Consortium

Good Clinical Practice for Clinical Research 2015 Stage 2 Refresher course CITI-Canada Collaborative Institutional Training Initiative AIHS Alberta Clinical Research Consortium

Tri-Council Policy Statement: Ethical Conduct for 2013 Research Involving Humans Course on Research Ethics (TCPS 2: CORE) Health Canada

Leadership Strategies for Information Technology in Health Care 2013 Harvard School of Public Health

Biomedical Research Ethics course 2013 CITI-Canada Collaborative Institutional Training Initiative AIHS Alberta Clinical Research Consortium

Danny J. Zuege September 18, 2020 Page 26 of 48

Good Clinical Practice for Clinical Research course 2013 CITI-Canada Collaborative Institutional Training Initiative AIHS Alberta Clinical Research Consortium

Responsible Conduct of Research course 2013 CITI-Canada Collaborative Institutional Training Initiative AIHS Alberta Clinical Research Consortium

Good Clinical Practice Investigator Responsibilities 2011 Glaxo-Smith-Kline sponsored Seminar

ARECCI Project Ethics Course Level 1 2010 How to Integrate an Ethical Approach in Quality Improvement and Evaluation Alberta Research Ethics Community Consensus Initiative Alberta Innovates – Health Solutions

Effective Approach Workshop - Calgary 2010 Canadian Blood Services

Physician Management Institute PMI V Course 2008 Canadian Medical Association (Vancouver, BC)

Serious Adverse Event Management/Clinical 2008 Safety Committees Training Course Calgary Health Region

Disclosure Training Course – Calgary 2007 Calgary Health Region

PMI III/IV Courses 2006 Canadian Medical Association (Niagra on the Lake, ON)

Interventional Bronchoscopy Course 2006 CHUM Hospital Group (Montreal, QB)

PMI I/II courses 2003 Canadian Medical Association (Victoria, BC)

Basic Modular Workshop (Resident Evaluation) 2002 Royal College of Physicians Surgeons Canada

ATLS Instructor Course 1999 University of Calgary

Danny J. Zuege September 18, 2020 Page 27 of 48

VII. RESEARCH SUPPORT

Peer-reviewed Grants/Contracts

Peer-reviewed Grants/Contracts - Principle Investigator

Measuring Clinical Frailty in an Electronic Medical 2015 - 2017 Record System: a Tool to Guide Clinical Care, Quality Improvement and Research Site: Alberta Health Services Support: Technology Value Network (Centres of Excellence of Canada) Amount: $100,000.00 (Co-PI)

Do Internal Jugular Vein Measurements Made By Ultrasound Correlate 2007 - 2010 with Fluid Responsiveness in Ventilated Post-Operative Cardiac Surgical Patients? Site: Calgary Health Region Support: Department of Critical Care Medicine Amount: $5000.00 (PI)

A randomized trial of empiric broad-spectrum antibiotics and invasive 2002 – 2005 diagnostic techniques in the setting of ventilator-associated pneumonia Site Principle Investigator Site: Peter Lougheed Hospital Support: CIHR (Multicentre Clinical Trial) Amount: $47,300.00 (site portion) (Site PI)

Hemodynamic effects of proportional assist ventilation in patients 1996 - 2001 post aortocoronary bypass grafting Site: Foothills Hospital, Calgary Support: Research and Development Committee, Foothills Hospital Amount: $5,271.00 (PI)

Sodium-potassium ATPase activity during the induction and resolution 1991 - 1992 of pulmonary edema Site: Respiratory Research Group, University of Calgary Support: Heart and Stroke Foundation of Canada (Research Fellowship) $39,000.00

Alberta Heritage Foundation for Medical Research (Equipment grant) $5,000.00 (Trainee awards)

Peer-reviewed Grants/Contracts - Coinvestigator

Venting Wisely - Transforming the provision of respiratory life support for Albertans Site: Alberta Health Services Support: Health Innovation Implementation and Spread (HIIS) Competition (Alberta Health/Alberta Health Services) (Application Submitted)

Danny J. Zuege September 18, 2020 Page 28 of 48

The Evaluation of a PRONe Positioning knowledge translation toolkit in 2020 - 2022 COVID-19 ARDS (PRONTO) study Site: Alberta Health Services Support: Alberta Innovates (COVID-19 Rapid Research Funding Opportunity) Amount: $363,285

Awake Prone Position in hypoxemic patients with Coronavirus Disease 19 2020 - 2021 Site: Alberta Health Services Support: CIHR (Operating Grant – COVID-19 Rapid Research Funding Opportunity) Amount: $2,178,410

Don’t Misuse My Blood: Reducing Avoidable Blood Tests and Avoidable Blood 2020 - 2023 Transfusions in Patients admitted to Critical Care and High-risk Surgical Units in Alberta Site: Alberta Health Services Support: - Alberta Innovates - Partnership for Research and Innovation in the Health System (PRIHS) Amount: $751,654

Moving Engagement Beyond the Bedside: Family-Partnered Delirium Prevention 2020 – 2022 Detection and Management in the Critically Ill. Site: Alberta Health Services Support: CIHR – Catalyst Grant – Patient Oriented Research Amount: $99,889

Minimizing Variation in Care and Improving Outcomes in Critically Ill patients 2020 - 2024 with respiratory failure through implementation and Evaluation of an Evidence-based Care Pathway Site: Alberta Health Services Support: CIHR – Project Grant Amount: $600,524

Re-EValuating the Inhibition of Stress Erosions (REVISE) Trial 2019 – 2021 Site: Peter Lougheed Centre (Site co-investigator) Support: CIHR (Multicentre Clinical Trial) Amount: $ 1,935,832 (Site Co-I)

REDUCE (RED blood cell Utilization in Critical Care) 2019 – 2021 Site: Alberta Health Services Support: Choosing Wisely Alberta Amount: $99,631

Evaluation of Oxygen Administration in Mechanically Ventilated Patients 2019 - 2020 Admitted to ICUs in Alberta Site: Alberta Health Services Support: Critical Care Strategic Clinical Network Amount: $20,000

Developing a Provincial Learning Healthcare System: An Innovative 2019 - 2020 Clinical Trial to Optimize Safe and Effective Use of Human Albumin Solutions Site: Alberta Health Services

Danny J. Zuege September 18, 2020 Page 29 of 48

Support: CIHR SPOR Innovative Clinical Trial Grant Amount: $98,312

Creating a Living Knowledge Translation Agenda to Improve the Delivery 2018 - 2021 of Evidence-based Care in Adult Critical Care Medicine Site: Alberta Health Services Support: CIHR Amount: $393,974

A Pragmatic Cluster, Randomized, Crossover, Registry-Embedded 2018 - 2020 Clinical Trial of Proton Pump Inhibitors vs. Histamine-2 Receptor Blockers for Stress Ulcer Prophylaxis Therapy in the Intensive Care Unit (PEPTIC Study) Site: Alberta Health Services Support: CIHR Amount: $317,475

Testing a Knowledge Translation Strategy to Improve Outcomes in 2018 - 2020 Critically Ill Patients with Respiratory Failure: Minimizing Variation in Care through the Implementation of an Evidence Based Care Bundle Support: MSI Foundation Amount: $89,000

Improving ICU-to-Ward Transfers of Care: Evaluation of a KT Tool Kit 2017 - 2019 and ICU Transfer Tool Site: Calgary Zone - Alberta Health Services Support: Canadian Frailty Network (Centres of Excellence of Canada) Amount: $265,148

Prioritization of Evidence-based Best Practices for Implementation 2017 - 2018 in Adult Critical Care Medicine Site: Alberta Health Services Support: MSI Foundation Amount: $89,000

Bacteremia antibiotic length actually needed for clinical effectiveness: 2016 - 2021 Randomized Controlled Trial (BALANCE study) Site: Peter Lougheed Centre (Site co-investigator) Support: CIHR (Multicentre Clinical Trial) Amount: $2,010,365 (Total grant funding) (Site Co-I)

Reengineering the Discharge of Elderly Patients from Intensive Care: 2016 - 2018 Pre-Clinical Evaluation of a Tool Kit Site: Alberta Health Services Support: Technology Value Network (Centres of Excellence of Canada) Amount: $99,938

Identifying and Evaluating Intensive Care Unit Capacity Strain in Alberta 2014 - 2018 Site: Alberta Health Services Support: Alberta Innovates (Health Solutions) Amount: $743,818

Danny J. Zuege September 18, 2020 Page 30 of 48

Reassessing Practices in the Daily Care of Critically Ill Patients: 2014 - 2018 Building Capacity and Methodology to Identify & Close Evidence-Care Gaps Site: Alberta Health Services Support: Alberta Innovates (Health Solutions) Amount: $748,790

Re-engineering ICU Discharge in the elderly: Development of an 2014 - 2016 Evidence-Informed Tool Site: Alberta Health Services Support: Technology Value Network (Centres of Excellence of Canada) Amount: $589,573

Use of a Smart Phone Application to Improve Antimicrobial Stewardship 2013 - 2014 Practices in Calgary Intensive Care Units Site: Alberta Health Services Support: Alberta Innovates Health Solutions (Alberta Sepsis Network) Amount: $37,000

Identifying Intensive Care Unit Discharge Planning Tools 2012 - 2014 Site: Alberta Health Services Support: CIHR Amount: $49,982

Oscillation for ARDS treated early (OSCILLATE) trial 2010 - 2012 Site: Peter Lougheed Hospital Support: CIHR (Multicentre Clinical Trial) (Site Co-I)

Performance Enhancement of the Canadian Nutrition Guidelines by a 2009 - 2012 Tailored Implementation Strategy: The PERFECTIS Study Site: Peter Lougheed Hospital Support: Kingston General Hospital (Site Co-I)

Critical care epidemiologic and biologic tissue bank resource (CCEPTR) 2009 - 2014 for infection and inflammation in the ICU Site: Alberta Health Services Support: Alberta Science and Research Authority (ASRA), Canadian Foundation for Innovation (CFI), University of Calgary

Age of blood evaluation (ABLE) trial in the resuscitation of critically ill patients 2009 - 2014 Site: Peter Lougheed Hospital Support: CIHR (Multicentre Clinical Trial) (Site Co-I)

Emergency department factors associated with the development of acute 2008 - 2012 lung injury in patients with severe sepsis or septic shock Site: Calgary Health Region Support: CHR Research Office Amount: $5,000

A retrospective review of feeding practices in the ICU after open abdominal 2007 - 2012 aortic aneurysm (AAA) repair Site: Peter Lougheed Hospital

Danny J. Zuege September 18, 2020 Page 31 of 48

Support: Canadian Foundation for Dietetic Research Amount: $4,920

Survival using Glucose Algorithm Regulation (NICE-SUGAR Trial) 2007 - 2010 Site: Peter Lougheed Hospital Support: CIHR (Multicentre Clinical Trial) (Site Co-I)

Prophylaxis of Thromboembolism in Critical Care (PROTECT Trial) 2006 - 2010 Site: Peter Lougheed Hospital Support: CIHR (Multicentre Clinical Trial) (Site Co-I)

Industry Sponsored Grants/Contracts

Investigator-Initiated Industry-Sponsored Grants

Implementation and Evaluation of Revised Protocols for Oral Hygiene for 2010 - 2016 Mechanically Ventilated Patients in Alberta Health Services Calgary Region – a Pilot Project Principle Investigator (local investigator-initiated industry-sponsored trial) Site: Alberta Health Services - Calgary Zone Support: SAGE Products Inc

Industry-Sponsored Grants – Site Principle Investigator

A Study to Explore the Distribution of Influenza, RSV and hMPV in Adults 2017 - 2019 Hospitalized with Acute Respiratory Tract Infection Site: Alberta Health Services – Calgary Zone Support: Janssen Ortho

A phase 3 randomized double-blind study of 2 IV gram-positive antibiotics 2013 - 2017 in ventilated gram-positive nosocomial pneumonia Site: Peter Lougheed Hospital Support: Trius/Cubist Pharmaceuticals

Treatment of Septic Shock by Inhibiting Auto-digestion and Preserving 2015 - 2016 Gut Integrity with Enteric LB1148 (SSAIL Study) Support: Leading Biosciences Inc.

A Phase III international, multi-center, randomized, double-blind, double- 2010 - 2015 dummy study to evaluate the efficacy and safety of 300 mg or 600 mg of intravenous zanamivir twice daily compared to 150 mg of oral oseltamivir twice daily in the treatment of hospitalized adults and adolescents with influenza Site: Peter Lougheed Hospital Support: GlaxoSmithKline

Efficacy and safety of drotrecogin alfa (activated) in adult patients with 2008 - 2012 septic shock Site: Alberta Health Services - Calgary Zone Support: Eli Lilly

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A pivotal, multicenter, multinational, randomized, double-blind, placebo- 2005 - 2007 controlled study to evaluate the efficacy and safety of TAK-242 in adults with severe sepsis Site: Peter Lougheed Hospital Support: Takeda Pharmaceutical Company Ltd.

A randomized double-blind placebo-controlled trial of prophylactic heparin 2003 - 2005 inpatients with severe sepsis and high disease severity who are undergoing treatment with drotrecogin alfa (activated) Site: Peter Lougheed Hospital Support: Eli Lilly

Efficacy and safety of drotecogin alfa (activated) in adult patients with early 2002 - 2005 stage severe sepsis Site: Peter Lougheed Hospital Support: Eli Lilly

Long-term follow-up of survivors from the PROWESS trial (an observational 2001 - 2002 study) Site: Peter Lougheed Hospital Support: Eli Lilly

A phase 3 study to demonstrate the safety and efficacy of recombinant 2001 - 2003 platelet-activating factor acetylhydrolase (rPAF-AH, Pafase) for reducing 28 day all cause mortality in patients with severe sepsis Site: Peter Lougheed Hospital Support: ICOS Corporation

A phase III study to determine the efficacy and safety for recombinant 1998 - 2001 human activated protein C in severe sepsis Site: Peter Lougheed Hospital Support: Eli Lilly

Multicenter, double-blind, placebo controlled, randomized phase 3 study 2000 – 2001 of tifacogin (recombinant tissue factor pathway inhibitor (rTFPI/SC-59735) in severe sepsis Site: Peter Lougheed Hospital Support: Chiron/Pharmacia

Industry-Sponsored Grants – Site Coinvestigator

A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study to 2019 – Present Assess the Safety and Efficacy of ART-123 in Subjects with Sepsis and Coagulopathy (Scarlet 2) Site: Peter Lougheed Hospital Support: Asahi Kasei Pharma America Corporation

A Phase III multicenter randomized double-blind active-controlled 2018 - 2020 study to assess the efficacy and safety of baloxavir marboxil in combination with a neuraminidase inhibitor versus a neuraminidase inhibitor alone in hospitalized patients with severe influenza Support: Roche

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Phase 2b, Multicenter, Randomized, Double-blind, Controlled Study to 2017 - 2018 Evaluate the Efficacy and Safety of Intravenous VIS410 in Addition to Oseltamivir (Tamiflu®) Compared with Oseltamivir Alone in Hospitalized Adults with Influenza A Infection Requiring Oxygen Support Site: Peter Lougheed Hospital Support: Visterra Inc

A Phase 2, Multicenter, Randomized, Double-Blind, Comparator-Controlled 2016 – 2018 Study of the Efficacy, Safety, and Pharmacokinetics of Intravenous Ulimorelin (LP101) in Patients with Enteral Feeding Intolerance Site: Peter Lougheed Hospital Support: Lyric Pharmaceutics Inc

Phase 2 randomized, double-blind placebo-controlled trial of MHAA4549A, a 2015 - 2018 monoclonal antibody in combination with oseltamivir versus oseltamivir for treatment of severe influenza infection Site: Peter Lougheed Hospital Support: Genetech

A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study to 2012 – 2018 Assess the Safety and Efficacy of ART-123 in Subjects with Severe Sepsis and Coagulopathy (Scarlet 1) Site: Peter Lougheed Hospital Support: Asahi Kasei Pharma America Corporation

Nutritional adequacy therapeutic enhancement in the critically ill: 2013 - 2016 A randomized double blind, placebo-controlled trial of the motilin receptor agonist GSK962040. The NUTRIATE Study Site: Peter Lougheed Hospital Support: GlaxoSmithKline

A randomized, double-blind, placebo-controlled study of the efficacy and 2008 - 2010 safety of TAK-242 versus placebo in subjects with sepsis induced cardiovascular and respiratory failure Site: Peter Lougheed Hospital Support: Takeda Pharmaceutical Company Ltd.

A Phase-3, Long-term, Open-Label, Multicenter Safety and Efficacy Study 2007 - 2010 of Ambrisentan in Subjects with Pulmonary Hypertension (Aries -3 study) Site: Peter Lougheed Hospital Support: Gilead

A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study of 2007 - 2010 the Safety and Efficacy of Interferon gamma-1b in Patients with Idiopathic Pulmonary Fibrosis (Inspire Study) Site: Peter Lougheed Hospital Support: InterMune

Effects of bosentan on morbidity and mortality in patients with Idiopathic 2007 - 2010 Pulmonary Fibrosis – a multicenter, double-blind, randomized, placebo-controlled, parallel group, event-driven, phase 111 study (Build-3 study) Site: Peter Lougheed Hospital Support: Actelion Pharmaceuticals Canada

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A Long-Term, Open-Label Study to Evaluate the Safety of Sitaxsentan 2007 - 2009 Sodium Treatment in Patients with Pulmonary Arterial Hypertension (STRIDE-3 study) Site: Peter Lougheed Hospital Support: Encysive

Effect of roflumilast on exacerbation rate in patients with COPD. A 52 2006 - 2009 weeks, double-blind study with 500ug roflumilast once daily versus placebo. Site: Peter Lougheed Hospital Support: Atlana Inc.

A randomized double-blind placebo controlled phase 3 three-arm study 2006 - 2010 of the safety and efficacy of pirfenidone in patients with idiopathic pulmonary fibrosis Site: Peter Lougheed Hospital Support: Intermune Inc.

A phase 3 long-term open-label multicentrer safety and efficacy study 2006 – 2008 of ambrisentan in subjects with pulmonary hypertension Site: Peter Lougheed Hospital Support: Myogen Inc.

The safety, pharmacokinetics, and pharmacodynamic effects of TNX 832 2005 - 2006 (Sunol-cH36) in patients with acute lung injury/acute respiratory distress syndrome Site: Peter Lougheed Hospital Support: Tanox Inc

A randomized double-blind placebo controlled multicenter study to 2005 - 2008 asses the efficacy safety and tolerability of bosentan in patients with mildly symptomatic pulmonary arterial hypertension Site: Peter Lougheed Hospital Support: Actelion Pharmaceuticals Canada

A prospective randomized double-blind placebo-controlled dose ranging 2005 - 2007 multicenter study of the safety and efficacy of three days continuous intravenous infusion of GR270773 in the treatment of suspected or confirmed gram-negative severe sepsis in adults Site: Peter Lougheed Hospital Support: GSK Canada

A multicenter, randomized, controlled trial comparing the safety and 2004 - 2006 effectiveness of Surfaxin (Lucinactant) delivered via bronchopulmonary segmental lavage to standard of care in patients with acute respiratory distress syndrome (ARDS) Site: Peter Lougheed Hospital Support: Discovery Laboratories Inc.

A phase 3, multicenter, randomized, placebo-controlled, double-blind, 2004 - 2009 three-arm study to evaluate the safety and efficacy of tifacogin (Recombinant Tissue Factor Pathway Inhibitor) administration in subjects with severe community-acquired pneumonia Site: Peter Lougheed Hospital Support: Chiron Corporation

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A Twelve Week Multi-Centre, Randomized, Double-Blind, Parallel Group, 2003 - 2006 Comparative Trial of Advair 50/100 mcg Diskus Inhalation Device BID versus Flovent 250 mcg Diskus Inhalation Device BID in Adolescents and Adults with Persistent Asthma Site: Peter Lougheed Hospital Support: GlaxoSmithKline

A 24 week placebo-controlled randomized parallel Group study comparing 2003 – 2005 roflumilast 500 mcg daily vs placebo on pulmonary function and respiratory symptoms in patients with COPD Site: Peter Lougheed Hospital Support: Atlana

A phase III study with freeze dried HL 10, three dosages of 200 mg/Kg 2002 – 2004 ideal body weight versus standard therapy in ALI/ARDS patients Site: Peter Lougheed Hospital Support: Leo Pharma

A phase II multicenter randomized double-blind placebo-controlled 2002 – 2003 parallel group dose-ranging evaluation of the safety and efficacy of hANP infusion (carperitide) in patients with acute respiratory distress syndrome (ARDS) Site: Peter Lougheed Hospital Support: Suntory Corporation

Spiriva assessment of FEV1 (SAFE). The effect of Inhaled tiotropium 2002 – 2005 bromide (18 ug once daily) on the change in FEV1 during long-term treatment in patients with COPD. Site: Peter Lougheed Hospital Support: Boehringer Ingelheim Canada

A comparison of treatment with 250ug roflumilast Versus placebo over 2002 – 2004 24 weeks in patients with chronic obstructive pulmonary disease (COPD). Site: Peter Lougheed Hospital Support: Altana Pharma Inc

Comparison of fluticasone (250ug bid) and ciclesonide (400ug od in the 2002 – 2004 morning or evening) in asthma therapy. Site: Peter Lougheed Hospital Support: Altana Pharma Inc

The effectiveness and safety of an individualized Symbicort TM Turbuhaler 2001 – 2002 maintenance dosing regimen versus Symbicort TM Turbuhaler given as regular twice daily therapy (SMART trial) Site: Peter Lougheed Hospital Support: AstraZeneca Canada

Gaining optimal asthma control (GOAL): A multicentre, stratified, 2001 - 2002 randomized, double-blind, parallel-group, step-up comparison of the level of asthma control achieved with salmeterol/fluticasone proprionate combination discus (Accuhaler) DPI compared with fluticasone proprionate discus (Accuhaler) alone in adults and adolescents Site: Peter Lougheed Hospital Support: GlaxoSmithKline

Danny J. Zuege September 18, 2020 Page 36 of 48

Multicentre, open label, single arm, safety study with Tracleer 2001 - 2002 (bosentan) in patients with pulmonary arterial hypertension Site: Peter Lougheed Hospital Support: Actelion Pharmaceuticals Canada

Real life effectiveness of Oxis Turbuhaler as needed in asthmatic 2000 – 2001 patients during six months (RELIEF) Site: Peter Lougheed Hospital Support: Astra Zeneca

Effect of tiotropium on exercise tolerance and static and dynamic 2000 – 2001 lung volumes in COPD patients (A randomized, double-blind, placebo-controlled, parallel group study) Site: Peter Lougheed Hospital Support: Boehringer Ingelheim Canada

A multi-centre, multinational, double-blind, placebo-controlled, group 2000 - 2001 comparative study to investigate the effects of Viozan™ (tid) via pMDI compared with placebo (tid) in adult patients with chronic obstructive pulmonary disease Site: Peter Lougheed Hospital Support: Convance

A randomized, double-blind, placebo-controlled, 12-week smoking 1999 - 2001 cessation trial of Zyban (150 mg bid) in adult smokers previously treated with Zyban Site: Peter Lougheed Hospital Support: Glaxo-Wellcome

12 week treatment with 500 ug roflumilast versus 10 mg montelukast 1999 - 2001 in patients with asthma Site: Peter Lougheed Hospital Support: BYK Canada

12 Weeks treatment with 200 or 800 ug/d ciclesonide versus placebo 1998 - 2001 followed by 40 weeks treatment with ciclesonide in asthmatic patients Site: Peter Lougheed Hospital Support: Byk Canada Inc.

A randomized, double-blind, within-patient, comparison of foradil 12 ug bid 1998 – 2000 and salbutomal 200 ug qid when added to regular treatment with ipratropium bromide 40 ug qid in patients with COPD Site: Peter Lougheed Hospital Support: Novartis

Identification of candidate asthma genes in DNA from peripheral blood from 1998 - 1999 asthmatics and their parents Site: Peter Lougheed Hospital Support: Boehringer Ingelheim

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A clinical and economic comparison of formoterol Turbuhaler versus 1997 - 1999 salmeterol and salbutamol pMDI in asthmatic patients not well-controlled on inhaled steroid therapy Site: Peter Lougheed Hospital Support: Astra

A multicenter open-label study to confirm the ability of montelukast sodium 1997 - 1999 to allow tapering of inhaled corticosteroids in asthmatic patients Site: Peter Lougheed Hospital Support: Merck-Frosst

IX. INVITED ADDRESSES

Primary Presenter

Zuege D. Connect Care – Coming Soon. Presented at Department of Critical Care Medicine Grand Rounds, Calgary, Feb, 2020.

Zuege D. Gastrointestinal Bleeding in the ICU – The Power of a Provincial Critical Care Clinical Information System. Presented at the Alberta Society of Intensive Care Physicians Conference, Lake Louise, Jan 2020.

Zuege D. Connect Care and Delirium. Presented at Learning Session #5, Critical Care Strategic Clinical Network, Calgary, Feb 2019.

Zuege D. Maximizing the impact of data in the ICU for research and QA. Presented at Department of Critical Care Medicine Clinical & Translational Research Frontiers Retreat, Calgary, Oct 2018.

Zuege D. Critical Care Informatics/Connect Care. Presented at Fall Critical Care Nursing Update, Calgary, Oct 2018.

Zuege D. The eCritical Alberta Program – The Past, The Present and The Future. Presented at Department of Critical Care Medicine Grand Rounds, Calgary, Dec 2017.

Zuege D. The Value of eCritical. Presented at eCritical Program Lunch and Learn Sessions, Alberta (Telehealth), Jan 2017.

Zuege D. eCritical for Critical Care Physicians. Presented at Red Deer Regional Hospital Critical Care Rounds, Red Deer, Feb 2016.

Zuege D. eCritical for Critical Care Physicians. Presented at Chinook Regional Hospital Critical Care Rounds, Lethbridge, Nov 2015.

Zuege D. eCritical for Critical Care Physicians. Presented at Medicine Hat Regional Hospital Medical Rounds, Medicine Hat, May 2015.

Zuege D, G Hind, K Panesar. Critical Care Informatics and Respiratory Therapy. Presented at CARTA (College and Association of Respiratory Therapists of Alberta) 2014 Annual Conference, Calgary, Oct 2014.

Zuege D, M Agyemang, S Seminowich. eCritical – Information Utilization in Critical Care. Presented to AHS Enterprise Business Intelligence Community Learning Session, Mar 2014.

Danny J. Zuege September 18, 2020 Page 38 of 48

Zuege D and G Duchsherer. CASS for VAP – are you in? Continuous aspiration of subglottic secretions for the prevention of ventilator associated pneumonia. Presented at PICU Grand Rounds, Alberta Childrens Hospital, Mar 2011.

Zuege D and L Knox. Prowess Shock Study – Musings Challenges and Success from Calgary. Presented at Prowess Shock Canadian Investigators Meeting, Toronto, Oct 2009.

Zuege D and M Ridic. Organ and Tissue Donation. Presented to ICU Grand Rounds, Lethbridge Regional Hospital, Mar 2009.

Zuege D. Sepsis and Ocular Donation. Presented to the Lions Eye Bank (Alberta) Annual Education Day, Calgary, Sept 2008.

Zuege D. Organ and Tissue Donation for Rural Practitioners. Presented at Rural Emergency Conference. Banff, Jan 2007.

Zuege D. ARDS – New and Upcoming Therapies. Presented at CARTA (College and Association of Respiratory Therapists of Alberta) 2006 Annual Conference, Calgary, Nov 2006.

Zuege D. Prevention of Ventilator-Associated Pneumonia. Presented at Safer Health Care Now Conference, Calgary, May 2005.

Zuege D. ARDS – Are we any further ahead? Presented at Respiratory Therapy Education Day, Calgary, Nov 2004.

Zuege D. Vasculitis. Presented to the Canadian Council of Cardiovascular Nurses, Calgary, Jan 1999.

Zuege D. Arterial Blood Gases. Presented at the Regional Conference Series, Vulcan, Alberta, Nov 1998.

Zuege D. The role of the sodium-potassium ATPase during the resolution of pulmonary edema. Presented to the Respiratory Research Group, University of Calgary, April 1993.

Zuege D, Bagley J, Berthiaume Y, and Schurch S. Correlation Between Surface Affinity and Adhesiveness of Normal Human Neutrophils. Presented at Heritage Medical Research Days, Edmonton, Alberta, November 1988.

Secondary Presenter (co-investigator)

Lord J, Palacios Mackay M, Zuege D, Roze des Ordons A, Lockyer J. Using generalizability theory to assess the dependability of scores from four assessment tools for central line insertion. Presented at Office of Health and Medical Education Scholarship (OHMES) conference, Calgary, Feb 2018.

Lord J, Palacios Mackay M, Zuege D, Roze des Ordons A, Lockyer J. Establishing validity evidence: assessing the dependability of scores from four assessment tools for competence in central line insertion. Presented at OHMES conference, Calgary, Feb 2018.

Lord J, Palacios Mackay M, Zuege D, Roze des Ordons A, Lockyer J. Using generalizability theory to assess the dependability of scores from four assessment tools for central line insertion. Presented at International Conference on Residency Education, Quebec City, Oct 2017.

Lord J, Palacios Mackay M, Zuege D, Roze des Ordons A, Lockyer J. Establishing validity evidence: assessing the dependability of scores from four assessment tools for central line competency. Presented at International Conference on Residency Education, Quebec City, Oct 2017.

Danny J. Zuege September 18, 2020 Page 39 of 48

Lord J, Palacios Mackay M, Zuege D, Roze des Ordons A, Lockyer J. Observed discrepancies between competence and confidence in central line insertion following a one-month ICU rotation. Presented at Association for Medical Education in Europe Annual Conference, Helsinki, Aug 2017.

Lord J, Palacios Mackay M, Zuege D, Roze des Ordons A, Lockyer J. Assessing the dependability of four assessment tools for central line insertion. Presented at Association for Medical Education in Europe Annual Conference, Helsinki, Aug 2017.

Lord J, Zuege D, Roze des Ordons A, Palacios-McKay M, Lockyer J. Impact of a one month ICU rotation on resident confidence and competence in central line insertion. Presented at Office of Health and Medical Education Scholarship Symposium, Calgary, Feb 2017.

Parfitt E, Campsall P, Missaghi B, Vaughan S, Chaubey V, Dalton B, Ross T, Zuege D, Gregson D, Conly, J. A smartphone application to improve antimicrobial stewardship practices in Calgary intensive care units. Presented at 2016 Peer Leader Symposium: Building Peer Leader Bridges to Advance Clinical Practice event, Toronto, March 2016.

Parfitt E, Campsall P, Missaghi B, Vaughan S, Chaubey V, Dalton B, Ross T, Zuege D, Gregson D, Conly, J. A smartphone application to improve antimicrobial stewardship practices in Calgary intensive care units. Presented at the Innovation Academy, Ward of the 21st Century, University of Calgary, Calgary, Nov 2013.

Wilson B, Cowan H, Elliot T, Zuege D, Lord J, Zygun D. Factors associated with the development of acute lung injury in emergency department patients with severe sepsis. Presented at Canadian Society of Internal Medicine, Halifax, Oct 2011.

Shahpori R, Kushniruk A, Hebert M, Zuege D. Tele-ICU; A Canadian Review. Presented at Information Technology and Communications in Health (ITCH) Conference, Victoria, BC Feb 2011.

Shahpori R, Kushniruk A, Hebert M, Zuege D. Tele-ICU Is there a need? Presented at 2010 e-Health Conference, Vancouver, BC May 2010.

Shahpori R, Delosangeles A, Ritchie P, Zuege D. Ventilator Associated Pneumonia (VAP) Surveillance System. Presented at 2008 e-Health Conference, Vancouver, BC May 2008.

Shahpori R, Delosangeles A, Ritchie P, Zuege D. Ventilator Associated Pneumonia Surveillance System Presented at 6th Annual Quality Improvement Forum, Calgary, Feb 2008.

Seminowitch S, Beninger C, Zuege D, Yilmaz S. Organ Procurement Database: Real Time Data Entry and Electronic Transfer of Information. Presented at Canadian Association of Transplantation meeting, Banff, Jan 2007.

X. PUBLICATIONS/PRESENTATIONS i. Peer reviewed manuscripts

Peer reviewed manuscripts - Published

1. Berthiaume Y, Zuege D, Bagley J, and Schurch S. Correlation Between Cell-substrate Adhesion of Two Neutrophils and Their Surface Properties in Aqueous Two-phase Polymer Solutions. Colloids and Surfaces 59:155-167, 1991.

2. Suzuki S, Zuege D, and Berthiaume Y. Sodium-independant Modulation of Na-K-ATPase Activity by Beta-adrenergic Agonist in Alveolar Type II Cells. Am. J. Physiol. 268 (Lung Cell Mol. Physiol. 12):L983- L990, 1995. Danny J. Zuege September 18, 2020 Page 40 of 48

3. Rosenal T, Patterson R, Wakefield S, Zuege D, Lloyd-Smith G. Physician Involvement in Hospital Information System Selection: A Success Story. MEDINFO 95 Proceedings 1(1):554-558, 1995.

4. Zuege D, Suzuki S, and Berthiaume Y. Activation of Lung Sodium-Potassium ATPase During the Recovery From High-permeability Pulmonary Edema. Am. J. Physiol. 271 (Lung Cell Mol. Physiol. 15):L896-L909, 1996.

5. Zuege D, and Mody C. Fungal Pneumonias in the Non-Immunocompromised Host. Clin. Pulm. Med. 4(5):254-265, 1997.

6. Zuege D, and Whitelaw W. Treatment of Acute Respiratory Failure in Chronic Obstructive Lung Disease. Curr. Opinion Pulm. Med. 3:190-197, 1997.

7. Mitchell J, Sas R, Zuege D, Doig C, Smith E, Whitelaw W, Tyberg, J, Belenkie I. Ventricular interaction during mechanical ventilation in closed-chest anesthetized dogs. Canadian Journal of Cardiology. 21(1):73-81, 2005.

8. Laupland K, Kirkpatrick A, Kortbeek J, Zuege D. Long-term Mortality Outcome Associated with Prolonged Admission to the Intensive Care Unit. CHEST 129:954-959, 2006.

9. Delaney A, Gray H, Laupland K, Zuege D. Kinetic bed therapy to prevent nosocomial pneumonia in mechanically ventilated patients: A systematic review and meta-analysis. Crit Care 10(3): R70 (EPub), 2006.

10. Zygun D, Zuege D, Boiteau P, Laupland K, Henderson E, Kortbeek J, Doig C. Ventilator-Associated Pneumonia in Severe Traumatic Brain Injury. Neurocritical Care 05:108-114, 2006.

11. The Canadian Critical Care Trials Group. A randomized trial of diagnostic techniques for ventilator- associated pneumonia. New Engl J Med 355(25):2619-2630, 2006. (D Zuege part of the Canadian Critical Care Trials Study Group for this study)

12. Esmail R, Duchscherer G, Giesbrecht J, King J, Ritchie P, Zuege D for the Ventilator Associated Pneumonia Team. Prevention of Ventilator Associated Pneumonia in the Calgary Health Region: A Canadian Success Story. Healthcare Quarterly 11:129-136, 2008.

13. Muscedere J, Dodek P, Keenan S, Fowler R, Cook D, Heyland D for the VAP Guidelines Committee and the Canadian Critical Care Trials Group. Comprehensive Evidence-Based Clinical Practice Guidelines for Ventilator Associated Pneumonia: Prevention. J. Crit Care 23:126-137, 2008. (D Zuege part of the VAP Guidelines Committee for this study)

14. Muscedere J, Dodek P, Keenan S, Fowler R, Cook D, Heyland D for the VAP Guidelines Committee and the Canadian Critical Care Trials Group. Comprehensive Evidence-Based Clinical Practice Guidelines for Ventilator-Associated Pneumonia: Diagnosis and Treatment. J. Crit Care 23:138-147, 2008. (D Zuege part of the VAP Guidelines Committee for this study)

15. Heyland D, Dodek P, Muscedere J, Day A, Cook D for the Canadian Critical Care Trials Group. Randomized trial of combination versus monotherapy for the empiric treatment of suspected ventilator- associated pneumonia. Crit Care Med 36(3):737-744, 2008. (D Zuege part of Canadian Critical Care Trials Study Group for this study)

Danny J. Zuege September 18, 2020 Page 41 of 48

16. Dalton B, Zuege D, Shahpori R, Laupland K. Lack of significant risk associated with concomitant ceftriaxone and intravenous calcium therapy in adult critical care patients. Ann of Pharmacotherapy 44 (7): 1158-63, 2010.

17. Wilson B, Cowan H, Lord J, Zuege D, Zygun D. The accuracy of pulse oximetry in emergency department patients with severe sepsis and septic shock: a retrospective cohort study. BMC Emerg Med 10(9), 2010.

18. Shahpori R, Kushniruk A, Hebert M, Zuege D. Tele-ICU - A survey of the attitudes and perspectives of critical care clinicians. J Crit Care. 26(3): 328.e9-328.e15, 2011.

19. Shahpori R, Kushniruk A, Hebert M, Zuege D. Tele-ICU - A Canadian Review. Stud Health Technol Inform. 164:420-4, 2011.

20. Ranieri V, Thompson B, Barie P, Dhainaut J, Douglas I, Finfer S, Gårdlund B, Marshall J, Rhodes A, Artigas A, Payen D, Tenhunen J, Al-Khalidi H, Thompson V, Janes J, Macias W, Vangerow B, Williams M; the PROWESS-SHOCK Study Group. Drotrecogin Alfa (Activated) in Adults with Septic Shock.. N Engl J Med. 366(22): 2055-64, 2012. (D Zuege part of Prowess Shock Study Group)

21. Ksienski M, Fenton T, Eliasziw M, Zuege D, Petrasek P, Shahpori R, Laupland K. A cohort study of nutrition practices in the intensive care unit following abdominal aortic aneurysm repair. JPEN J. Parenter Enteral Nutr. 37:261-267, 2013.

22. Stelfox H, Perrier L, Straus S, Ghali W, Zygun D, Boiteau P, Zuege D. Identifying Intensive Care Unit Discharge Planning Tools: Protocol for a Scoping Review. BMJ Open. 3(4): e002653, 2013.

23. Kramer A, Zygun D, Doig C, Zuege D. Incidence of neurologic death among patients with brain injury: a prospective cohort study in a Canadian health region. CMAJ. 185 (13):E838-E845, 2013.

24. Stelfox H, Lane D, Boyd J, Taylor S, Perrier L, Straus S, Zygun D, Boiteau P, Zuege D. A Scoping Review of Patient, Provider and Institutional Factors that Impact Patient Discharge from Intensive Care. CHEST, 147(2):317-327, 2015.

25. Stelfox HT, Niven DJ, Clement FM, Bagshaw SM, Cook DJ, McKenzie E, Potestio ML, Doig CJ, O'Neill B, Zygun D; Critical Care Strategic Clinical Network, Alberta Health Services (D Zuege part of the Critical Care Strategic Clinical Network). Stakeholder Engagement to Identify Priorities for Improving the Quality and Value of Critical Care. PLoS One. 2015 Oct 22;10(10): e0140141. doi: 10.1371/journal.pone.0140141. eCollection 2015.

26. Chin T, Kushner B, Dersh-Mills D, Zuege D. Antibiotic Utilization Patterns in Patients with Ventilator Associated Pneumonia - A Canadian Context. Can J Infect Dis Med Micro. 2016:3702625. doi: 10.1155/2016/3702625. Epub Jul 20 2016.

27. Morrison LK, Kromm J, Gaudet J, Zuege D, Button B, Warshawski F and Lucyk SN. Rescue Extracorporeal Membrane Oxygenation Therapy in Acute Cardiomyopathy Related to Methamphetamine Toxicity. Can J Emerg Med, July 31 1-6 (Epub), 2017.

28. McKenzie E, Potestio M, Boyd J, Niven D, Brundin-Mather R, Bagshaw S, Stelfox T on behalf of the Improving Daily Care in the ICU Panel (D Zuege part of the Improving Daily Care in the ICU Panel). Reconciling Patient and Provider Priorities for Improving the Care of Critically Ill Patients: A Qualitative Analysis of Decision Making. Health Expectations 20(6):1367-1374, 2017.

29. Bagshaw S, Wang X, Zygun D, Zuege D, Dodeck P, Garland A, Scales D, Berthiaume L, Faris P, Chen G, Opgenorth D, Stelfox HT. Association between strained capacity and mortality among patients admitted to intensive care: A path-analysis modeling strategy. J Crit Care. 43:81-87, 2017.

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30. Hudson D, Kushniruk A, Borycki E, Zuege D. Assessment of usability and physician satisfaction with a provincially implemented critical care clinical information system. Int J Med Informatics 112:131-136, 2018.

31. Posadas-Calleja J, Stelfox T, Ferland A, Zuege D, Niven D, Berthiaume L, Doig C. Derivation of a PIRO score for predicting mortality in a cohort of ICU patients with surgical-related intra-abdominal sepsis. Am J Crit Care 27(4):287-294, 2018.

32. Hall A, Stelfox HT, Wang X, Chen G, Zuege D, Dodek P, Garland A, Scales DD, Berthiaume L, Zygun D, Bagshaw SM. Association Between Afterhours Admission to the Intensive Care Unit, Strained Capacity, and Mortality: A Retrospective Cohort Study. Crit Care 22(1):97, 2018.

33. Brundin-Mather R, Soo A, Zuege DJ, Niven DJ, Fiest K, Doig CJ, Zygun D, Boyd J, Parsons Leigh J, Bagshaw S, Stelfox HT. Secondary EMR data for quality improvement and research: A comparison of manual and electronic data collection from an integrated critical care electronic medical record system. J Crit Care 47:295-301, 2018.

34. Bagshaw S, Stelfox H, Iwashyna T, Zuege DJ, Wang X. Timing of Onset of Persistent Critical Illness in Canada: A Population-Based Study. Intensive Care Medicine 44(12):2134-2144, 2018.

35. Stelfox HT, Brundin-Mather R, Soo A, Parsons Leigh J, Niven DJ, Fiest KM, Doig CJ, Zuege DJ, Kushner B, Clement F, Straus SE, Cook DJ, Bagshaw SM, Sauro KM. A Multicentre Controlled Pre-Post Trial of an Implementation Science Intervention to Improve Venous Thromboembolism Prophylaxis in Critically Ill Patients. Intensive Care Medicine 45(2):211-222, 2019.

36. Tran D, Thanh N, Opgenorth D, Wang X, Zuege DJ, Zygun D, Stelfox H, Bagshaw S. Association between strained ICU capacity and healthcare costs in Canada: A population-based cohort study. J Crit Care 51:175-183, 2019.

37. Soo A, Zuege DJ, Fick G, Niven D, Berthiaume L, Stelfox HT, Doig C. Describing organ dysfunction in the intensive care unit: a cohort study of 20,000 patients. Critical Care 23(1):186, 2019.

38. Montgomery CL, Zuege DJ, Rolfson DB, Opgenorth D, Hudson D, Stelfox HT, Bagshaw SM. Implementation of Population-Level Screening for Frailty Among Patients Admitted to Adult Intensive Care in Alberta, Canada. Can J Anesth 66(11):1310-1319, 2019.

39. Lord JA, Zuege DJ, Palacios Mackay M, Roze des Ordons A, Lockyer J. Picking the right tool for the job: a reliability study of four assessment tools for central venous catheter insertion. Journal of Graduate Medical Education 11(4):422-429, 2019.

40. Tagliabue G, Ji M, Suneby-Jagers J, Zuege DJ, Kortbeek J, Easton P. Distinct neural-mechanical efficiency of costal and crural diaphragm during hypercapnia. Respiratory Physiology & Neurobiology 268:103247, 2019.

41. Parhar KKS, Lequier L, Blackwood J, Zuege DJ, Singh G. Optimizing provision of extracorporeal life support during the COVID-19 pandemic: practical considerations for Canadian jurisdictions. CMAJ April 06, 2020 192 (14) E372- E374; DOI: https://doi.org/10.1503/cmaj.200448

42. Parhar K, Stelfox HT, Fiest KM, Rubenfeld GD, Zuege DJ, Knight G, Robertson H, Soo A, Doig C, Niven D. The Effect of Standardized Management for treatment of Hypoxemic Respiratory Failure and ARDS on Patient Survival: A Systematic Review and Meta-analysis. CHEST, 2020 (In Press).

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43. Bagshaw SM, Tran DT, Opgenorth D, Wang X, Zuege DJ, Ingolfsson A, Stelfox HT, Thanh NX. Assessment of costs of avoidable delays in intensive care unit discharge. JAMA Network Open, 2020. (In Press)

44. Weatherald J, Solverson K, Zuege DJ, Loroff N, Fiest KM, Parhar K. Awake Prone Positioning for COVID-19 Hypoxemic Respiratory Failure: A Rapid Review. J Crit Care, 2020. (In Press)

45. Hessey E, Montgomery C, Zuege DJ, Rolfson D, Stelfox HT, Fiest K, Bagshaw SM. Sex-Specific Prevalence and Outcomes of Frailty in Critically Ill Patients. J Intensive Care, 2020. (In Press)

Peer reviewed manuscripts - Submitted

Bagshaw SM, Hall A, Wang X, Zuege DJ, Opgenorth D, Scales DC, Stelfox HT. Association between Afterhours Discharge from the Intensive Care Unit and Hospital Mortality: A Multi-Centre Retrospective Cohort Study. Submitted to J Crit Care, 2020.

Lucini FR, Krewulak K, Fiest K, Bagshaw SM, Zuege DJ, Lee J, Stelfox HT. Natural language processing to measure communication between healthcare providers and family members of critically ill patients. Submitted to Journal of the American Med Inform Assoc, 2020.

Boyd JM, James MT, Zuege DJ, Stelfox HT. Development and evaluation of models to predict readmission or death after discharge from intensive care. Submitted to Critical Care, 2020.

Tagliabue G, Ji M, Suneby Jagers J, WooSurng L, Dean D, Zuege DJ, Wilde E, Easton P. Limitations of Surface EMG Estimate of Parasternal Intercostal to Infer Neural Respiratory Drive. Submitted to CHEST 2019.

Parhar K, Stelfox HT, Knight G, Soo A, Zuege DJ, Rubenfeld GD et al. Treatment of Hypoxemic Respiratory Failure and ARDS with Protection, Paralysis, and Proning (TheraPPP) Pathway: a protocol for a pilot before and after study. Submitted to BMC Health Serv Res, 2020.

Tagliabue G, Ji M, Suneby Jagers J, Zuege DJ, Kortbeek J, Easton P. Parasternal, intercostal, costal and crural diaphragm neural activation during hypercapnia. Submitted to J App Physiol, 2020.

Parhar K, Zuege DJ, Shariff K, Knight G, Bagshaw SM. Prone Positioning for ARDS patients – A review and users guide for the COVID-19 pandemic. Submitted to Can J. Anesth, 2020.

ii. Abstracts – Published (Peer Reviewed)

1. Berthiaume Y, Zuege D, Bagley J, and Schurch S. Correlation Between Surface Affinity and Adhesiveness of Normal Human Neutrophils. Eur. Resp. Journal 2:S505, 1989.

2. Suzuki S, Zuege D, and Berthiaume Y. Na+-K+-ATPase Activity in Lung Homogenate and Alveolar Type II Cells: Inhibition by Deoxycholic Acid. Am. Rev. Resp. Dis. 145(4):A365, 1992.

3. Zuege D, Suzuki S, and Berthiaume Y. The Sodium-Potassium ATPase is Stimulated During Recovery From High Permeability Pulmonary Edema. Clin. Invest. Med. 15(4):A138, 1992.

4. Suzuki S, Zuege D, and Berthiaume Y. Beta-adrenergic agonist increases Na-K ATPase Activity in Cultured Rat Alveolar Type II Cells. Clin. Invest. Med. 15(4):A138, 1992.

5. Zuege D, Suzuki S, and Berthiaume Y. Activation of Lung Sodium-Potassium ATPase During the Recovery From High Permeability Pulmonary Edema. Am. Rev. Resp. Dis. 147(4):A42, 1993. Danny J. Zuege September 18, 2020 Page 44 of 48

6. Suzuki S, Zuege D, and Berthiaume Y. Acute Effects of Terbutaline and Dibutyryl cAMP on Na-K- ATPase Activity in Cultured Rat Alveolar Type II Cells. Am. Rev. Resp. Dis. 147(4):A1010, 1993.

7. Zuege D, Suzuki S, and Berthiaume Y. Activation of Lung Sodium-Potassium ATPase During the Recovery From Alveolar Flooding in Rats. Clin. Invest. Med. 16(4):B121, 1993.

8. Zuege D, Ford D, Hecker J, Scott S, and Viner S. Hemodynamic Effects of Proportional Assist Ventilation (PAV) In Patients Post Aorto-coronary Bypass Grafting. Am. J. Resp. Crit. Care Med. 157(4): A278, 1998.

9. Zuege D, Hendersen E, Boiteau P, et al. Incidence of ventilator-associated pneumonia (VAP) in Canadian Intensive Care Units (ICU). Am. J. Resp. Crit. Care Med. 163(5): A26, 2001.

10. Helmersen D, Ainslie M, Zuege D et al. Positive anti-PR-3 (ANCA) and anti-GBM antibody tests associated with pulmonary tuberculosis. CHEST 120(4 Suppl): 342S, 2001.

11. Henderson E, Zuege D, Boiteau P, et al. Incidence of ventilator-associated pneumonia (VAP) in Three Canadian Intensive Care Units (ICU). Proceedings of the 2001 Conjoint Meeting of the Canadian Association of Clinical Microbiology and Infectious Diseases (CACMID), Community and Hospital Infection Control Association – Canada (CHICA), and the Canadian Infectious Disease Society (CIDS), 2001.

12. Zuege D, Laupland K, Boiteau P, et al. Etiology of ventilator associated pneumonia in a population- based intensive care unit cohort. Am. J. Resp. Crit. Care Med. 167(7): A266, 2003.

13. Henderson E, Zuege D, Laupland K, Boiteau P, Ross C, Ritchie P, Stoesz J, Sissons K, Lye T, Louie T. Etiology of ventilator associated pneumonia (VAP) in a population-based intensive care unit. Proceedings of the 2003 Conjoint Meeting of the Canadian Association of Clinical Microbiology and Infectious Diseases (CACMID), Community and Hospital Infection Control Association – Canada (CHICA), and the Canadian Infectious Disease Society (CIDS), 2003.

14. Henderson E, Zuege D, Boiteau P, Ross C, Ritchie P, Stoesz J, Sissons K, Alfieri N, Louie T. Incidence of Ventilator Associated Pneumonia (VAP) in 3 Canadian Intensive Care Units (ICUs). Proceedings of the 2003 Conjoint Meeting of the Canadian Association of Clinical Microbiology and Infectious Diseases (CACMID), Community and Hospital Infection Control Association – Canada (CHICA), and the Canadian Infectious Disease Society (CIDS), 2003.

15. Bagshaw S, Pettersen J, Zuege D, Viner S, Clark A, Klassen B, White C. Lead neuropathy with histologic similarities to giant axonal neuropathy: A case report. Can J Neurol Sciences 32(Suppl 1): S41, 2005.

16. Yau, P, Alakija, K, Laupland K, D. Zuege. Chronic Respiratory Disease due to Mediastinal Lipomatosis in an Individual with Dwarfism: Case and Autopsy Reports. Pathol Res and Practice 202(11): 808, 2006.

17. Ritchie P, Ross C, Shahpori R, Zuege D, et al. No Need to Leave my Desk: Web-based VAP Surveillance. Canadian Journal of Infection Control 22(1): 46-7, 2007.

18. Ksienski M, Fenton T, Laupland K, Zuege D, Petrasek P, Shahpori R. A retrospective review of feeding practices in the intensive care unit following abdominal aortic aneurysm repair. J Parenter Enteral Nutr. 35(1): S28, 2011.

19. Wilson B, Cowan H, Elliot T, Zuege D, Lord J, Zygun D. Early risk factors for the development of acute lung injury in patients with severe sepsis. Presented at Canadian Critical Care Forum, Toronto, Nov 2011. http://www.criticalcarecanada.com/abstracts/2011/early_risk_factors_for_the_development_of_acute_lung_i njury_in_patients_with_severe_sepsis.aspx

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19. Kramer A, Zygun D, Doig C, Zuege D. Declining incidence of neurological death. Presented at the ANIM Arbeitstagung NeuroIntensiv- und Notfallmedizin (Neurocritical Care) conference, Mannheim, Germany, Jan 2013. http://registration.akm.ch/einsicht.php?XNABSTRACT_ID=159109&XNSPRACHE_ID=1&XNKONGRESS_I D=174&XNMASKEN_ID=900

20. Parfitt E, Campsall P, Missaghi B, Vaughan S, Chaubey V, Dalton B, Ross T, Zuege D, Gregson D, Conly J. A Smartphone Application to Improve Antimicrobial Stewardship Practices in Calgary Intensive Care Units. Association of Medical Microbiology and Infectious Disease Canada Conference, Quebec City, Apr 2013.

21. Melvin C, Harding L, Boleantu B, Pai A, Zuege D. eCritical Alberta – A Provincial Critical Care Clinical Information System. eHealth 2013 Conference, Ottawa, May 2013.

22. Linton K, Blanchard I, Doig C, Dowling S, Moir G, Zuege D, Henderson E. The impact of ventilator associated pneumonia among pre-hospital intubated patients. 2013 Community and Hospital Infection Control Association – Canada (CHICA) National Education Conference, Ottawa, June 2013.

23. Bagshaw S, Wang X, Zygun D, Zuege D, Zygun D, Dodeck P, Garland A, Scales D, Berthiaume L, Yergens D, Faris P, Chen G, Stelfox HT. Capacity Strain Increases Mortality Risk among Patients Admitted to Intensive Care Units – A Two-Stage Modeling Strategy. Presented at Canadian Critical Care Forum, Toronto, Oct 2015.

24. Hudson D, Zuege D. Physician Satisfaction with a Provincial Critical Care Information System. Presented at eHealth 2016 Conference, Vancouver, June 2016.

25. Hudson D, Zuege D. Understanding How Physicians Process Data in a Critical Care Electronic Medical Record. Presented at eHealth 2016 Conference, Vancouver, June 2016.

26. Robinson SR, Campsall P, Parfitt E, Conly J, Dalton B, Stokes W, Kushner B, Vaughan S, Missaghi B, Chaubey V, Gregson D, Zuege D. Impact of an Innovative Smartphone “App” on Intensive Care Unit (ICU) Antimicrobial Utilization Across a Large Metropolitan Health Region in Canada: an Interrupted Time Series Analysis. Presented at IDWeek Conference, New Orleans, Oct 2016. Open Forum Infectious Diseasees 3 (Suppl 1), Dec 2016.

27. Soo A, Zuege D, Fick G, Niven D, Berthiaume L, Stelfox HT, Doig C. Describing Organ Dysfunction in the ICU. Presented at SCCM Conference, Honolulu, Jan 2017.

28. Hall A, Stelfox HT, Wang X, Chen G, Zuege D, Dodeck P, Garland A, Scales D, Berthiaume L, Zygun D, Bagshaw S. Association between after hours admission to the intensive care unit and mortality. Presented at the Alberta Society of Intensive Care Physicians Conference, Banff, Jan 2017.

29. Lord J, Palacios Mackay M, Zuege D, Roze des Ordons A, Lockyer J. Impact of a one month ICU rotation on resident confidence and competence in central line insertion. Presented at OHMES conference, Calgary, Apr 2017.

30. Lord J, Palacios Mackay M, Zuege D, Roze des Ordons A, Lockyer J. Observed discrepancies between competence and confidence in central line insertion following a one-month ICU rotation. Presented at Association for Medical Education in Europe Annual Conference, Helsinki, Aug 2017.

31. Lord J, Palacios Mackay M, Zuege D, Roze des Ordons A, Lockyer J. Assessing the dependability of four assessment tools for central line insertion. Presented at Association for Medical Education in Europe Annual Conference, Helsinki, Aug 2017.

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32. Lord J, Palacios Mackay M, Zuege D, Roze des Ordons A, Lockyer J. Using generalizability theory to assess the dependability of scores from four assessment tools for central line insertion. Presented at International Conference on Residency Education, Quebec City, Oct 2017.

33. Lord J, Palacios Mackay M, Zuege D, Roze des Ordons A, Lockyer J. Establishing validity evidence: assessing the dependability of scores from four assessment tools for central line competency. Presented at International Conference on Residency Education, Quebec City, Oct 2017.

34. Lord J, Palacios Mackay M, Zuege D, Roze des Ordons A, Lockyer J. Using generalizability theory to assess the dependability of scores from four assessment tools for central line insertion. Presented at OHMES conference, Calgary, Feb 2018.

35. Lord J, Palacios Mackay M, Zuege D, Roze des Ordons A, Lockyer J. Establishing validity evidence: assessing the dependability of scores from four assessment tools for competence in central line insertion. Presented at OHMES conference, Calgary, Feb 2018.

36. Vis D, Soo A, Zuege D. Ventilator Associated Complications: Development and validation of an automated detection algorithm and application in a population-based cohort of adult critical care patients in Alberta. Presented at the American Thoracic Society conference, San Diego, May 2018.

37. Montgomery C, Bagshaw S, Stelfox HT, Rolfson D, Zuege D, Zygun D, Hudson D, Openorth D. Frailty in Critical Illness from an Alberta Perspective. Presented at Critical Care Medicine Research Day, University of Alberta, May 2018.

38. Hall A, Stelfox HT, Wang X, Chen G, Zuege D, Dodeck P, Garland A, Scales D, Berthiaume L, Zygun D, Bagshaw S. After hours discharge from the intensive care unit increases all-cause hospital mortality: A retrospective cohort study. Presented at Critical Care Medicine Research Day, University of Alberta, May 2018.

39. Thanh T, Chen G, Zygun D, Zuege D, Stelfox HT, Bagshaw SM. Healthcare Costs Of Strained Intensive Care Unit Capacity. Presented at HTAi Annual Meeting Cologne, Germany June 2019.

40. Bagshaw SM, Niven D, Soo A, Harris J, Mathew S, Sargento A, Agyemang M, Zuege DJ. Development and Validation of an Electronic Algorithm to Detect Clinically Significant Gastrointestinal Bleeding Events in Alberta, Canada. Presented at World Congress of Intensive Care Medicine, Melbourne, Australia, Oct 2019. (Best Safety & Quality Paper Award, ANZICS)

41. Zuege DJ, Niven D, Soo A, Harris J, Mathew S, Sargento A, Agyemang M, Bagshaw SM. Clinically Significant Gastrointestinal Bleeding Events: Development and Validation of an Electronic Detection Algorithm and Application in a Population-Based Retrospective Cohort Study of Adult Critically Ill Patients in Alberta. Presented at Canadian Critical Care Forum, Toronto, Nov 2019.

42. Hessey E, Montgomery C, Zuege D, Rolfson D, Stelfox H, Bagshaw S. Sex-Specific Prevalence, Correlates and Outcomes of Frailty in Critically Ill Patients. Presented at Canadian Critical Care Forum, Toronto, Nov 2019.

43. Morrissey J, Bowker SL, Sinnadurai S on behalf of the Alberta Critical Care Strategic Clinical Network (D Zuege Medical Director). Driving clinical best practice through a provincial audit and feedback approach: Alberta’s ICU Delirium Initiative. Presented at Canadian Critical Care Forum, Toronto, Nov 2019.

44. Sinnadurai S, Bowker SL, Morrissey J on behalf of the Alberta Critical Care Strategic Clinical Network (D Zuege Medical Director). Advancing Implementation Science in Alberta’s Critical Care Community and Supporting a Lear`ning Health System through Collaboration: The Provincial ICU Delirium Initiative. Presented at Canadian Critical Care Forum, Toronto, Nov 2019.

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iii. Communications

1. Esmail R, Zuege D, Duchsherer G. Consistent compliance with the ventilator-associated pneumonia (VAP) bundle can reduce VAP. Abstract presented at SaferHealthCare Now Conference, Montreal, 2007.

2. Wilson B, Zuege D, Lord J, Zygun D. Emergency department factors associated with the development of acute lung injury in patients with severe sepsis. Abstract presented at Emergency Medicine Research Day, Calgary, May 2008.

3. The eCritical Alberta Team (D Zuege – Medical Director). eCritical Alberta – A New Clinical Information System for Critical Care. Abstract presented at Alberta Health Services Strategic Clinical Network Conference, Edmonton, June 2012.

4. Conly J, Zuege D. SPECTRUM-MD antimicrobial App. Article for UToday, University of Calgary, June 2016.

5. Zuege D. eCritical Enhances Care for Alberta’s Sickest Patients. Article for AHS 2015-16 Annual Report, Alberta Health Services, 2016.

6. Vis D, Zuege D. Ventilator Associated Events: Development and validation of an automated detection algorithm and application in a population-based cohort of adult critical care patients in Alberta. Presented at Department of Medicine Resident Research Day, Calgary, May 2017 (Best Poster Award – Health Services Research).

7. Spence S, Lee C, Boiteau P, Gregson D, Zuege DJ, Laupland K, Niven DJ. Epidemiology of Blood Culture Orders in Critically Ill Adults: A Retrospective Cohort Study. Presented at Department of Critical Care Medicine Research Day, Calgary, Sept 2019.

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