Biology of Differentiation & Cancer

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1st SignGene Winter School Biology of Differentiation & Cancer Technion, Israel Institute of Technology, Haifa, Israel January 27-29, 2014 Speakers Topics Yinon Ben-Neriah, Hebrew University of Jerusalem, Israel • Transcription factor networks in dierentiation Yehudit Bergman, Hebrew University of Jerusalem, Israel and cancer Walter Birchmeier, Max Delbrück Center, Berlin, Germany • Epigenetics and nuclear organization Daniel Chamovitz, Tel Aviv University, Israel • Genetics and functional genomics Robert Eisenman, FHCRC, Seattle, USA • Signaling pathways in development and cancer Or Hakim, Bar-Ilan University, Ramat Gan, Israel • Cellular microenvironment Shai Izraeli, Tel Aviv Univeristy, Israel • Cancer models Tommy Kaplan, Hebrew University of Jerusalem, Israel Batsheva Kerem, Hebrew University of Jerusalem, Israel Organizers Achim Leutz, Max Delbrück Center, Berlin, Germany Amir Orian, Achim Leutz, Undine Hill, Eduardo Moreno, University of Bern, Switzerland Sylvia Zérath-Gurevich & Sabine Loewer Amir Orian, Technion, Haifa, Israel German-Israeli Helmholtz Research School Gera Neufeld, Technion, Haifa, Israel Moshe Oren, Weizmann Institute of Science, Rehovot, Israel SignGene Frontiers in Cell Signaling and Gene Regulation Tzachi Pilpel, Weizmann Institute of Science, Rehovot, Israel Benjamin Podbilewicz, Technion, Haifa, Israel Registration & Abstract Submission Klaus Rajewsky, Max Delbrück Center, Berlin, Germany http://www.mdc-berlin.de/signgeneschool2014 Yardena Samuels, Weizmann Institute of Science, Rehovot, Israel Clemens Schmitt, Charité , Berlin, Germany Yuval Shaked, Technion, Haifa, Israel Contact Sabine Loewer, Max Delbrück Center, Berlin, Germany Phillippe Soriano, Mount Sinai School of Medicine, New York, USA e-mail: [email protected] Israel Vlodavsky, Technion, Haifa, Israel Sigal Alfasi-Izrael, Technion, Haifa, Israel Yosef Yarden, Weizmann Institute of Science, Rehovot, Israel e-mail: [email protected] www.mdc-berlin.de/signgeneschool2014.

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The Thing Inside Each Organism That Is in Charge
Anatomy Physiology & Biochemistry International Journal Review Article Anatomy Physiol Biochem Int J Volume 1 Issue 1 - July 2016 Copyright © All rights are reserved by Julius Adler A Search for the Boss: The Thing inside Each Organism That Is in Charge *Julius Adler Departments of Biochemistry and Genetics, University of Wisconsin, USA Submission: April 20, 2016; Published: July 26, 2016 *Corresponding author: Julius Adler, Departments of Biochemistry and Genetics, University of Wisconsin-Madison, Madison, Wisconsin53706, USA, Email: Abstract It is proposed that every organism is controlled by The Boss. The Boss is in charge of each organism’s behavior, metabolism, development, immune response, and reproduction. All organisms have perhaps the same Boss. This is an unknown mechanism. An example is behavior: in people and other primates, The Boss acts at the prefrontal cortex of the brain to direct the behavior of the organism by means of executive function. It is proposed that simpler versions of a prefrontal cortex occur also in other animals and in plants and in microorganisms. Thus The Boss directs the behavior of all organisms. Keywords: Executive Function; Global Regulators; Biochemistry; Neurobiology; Genetics; Bacteriology Introduction This has been a century of great accomplishments in the Behavior, Metabolism, Development, Immunological biological sciences. We have learned a vast amount of what Response, Reproduction organisms do and how they do it, all the way from microorganisms Behavior and its Control to plants to animals including humans. But the search for what Behavior in Humans and in other Primates: Starting in ties it all together (if anything) has been avoided and the answer the 1870’s it became apparent to some psychologists that there is unknown.
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