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provided by Elsevier - Publisher Connector Journal of Orthopaedic Translation (2016) 7, 138e154

Available online at www.sciencedirect.com ScienceDirect

journal homepage: http://ees.elsevier.com/jot

Titles of other abstracts

17 31 Outcome of Ponseti treatment in idiopathic club foot in school-aged Knee osteoarthritis: Bone marrow lesions detected by specific MRI sequences children associated with severity of osteochondral degeneration Ranjeet Kumar, Anisuddin Bhatti Findlay D.M.a, Muratovic D.a, b, Cicuttini F.M.c, Wluka A.E.c, Wang Y.c, Otto S.d, Taylor D.e, Humphries J.M.b, Lee Y.R.a, Labrinidis A.f, Williams R.E.f, Mercer G.g, Jinnah Postgraduate Medical Centre Kuliwaba J.S.a, b 18 a Discipline of Orthopaedics and Trauma, School of Medicine, The University of Ultrastructural origin of bone fragility Adelaide, Adelaide, Australia b Xiaodu Wang Bone and Joint Research Laboratory, SA Pathology, Adelaide, Australia c University of Texas at San Antonio Department of Epidemiology & Preventive Medicine, Monash University, Melbourne, Australia 19 d Anatomical Pathology, SA Pathology, Adelaide, Australia Prevention of premature senescence by melatonin rescues osteogenesis in e Department of Radiology, Royal Adelaide Hospital, Adelaide, Australia mesenchymal stem cells f Adelaide Microscopy, The University of Adelaide, Adelaide, Australia Fan Hea, b, Long Zhoua, b, Xi Chena, b, Zong-Ping Luoa, b, Huilin Yanga, b g Department of Orthopaedics, Repatriation General Hospital, Adelaide, Australia a Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Suzhou, China 32 b Orthopaedic Institute, Medical College, Soochow University, Suzhou, China The study on a novel bone targeting delivery system carrying phytomolecule for prevention of steroid-associated osteonecrosis in rat model 20 Shihui Chena, d, Lizhen Zhenga, Jiayong Zhangc, Zhijun Yangc, Xinluan Wanga, b, Enhancement of antioxidant properties of human umbilical cord-derived Ling Qina, b mesenchymal stem cells by decellularized extracellular matrix a Musculoskeletal Research Laboratory, Department of Orthopaedics & a, b c a, b a, b a, b Fan He , Xiaozhen Liu , Long Zhou , Xi Chen , Zong-Ping Luo , Yihong Traumatology, The Chinese University of Hong Kong, Hong Kong SAR, PR China Gongc, Huilin Yanga, b b Translational Medicine R&D Center, Shenzhen Institutes of Advanced Technology, a Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Chinese Academy of Sciences, Shenzhen, PR China Suzhou, China c School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, PR b Orthopaedic Institute, Medical College, Soochow University, Suzhou, China China c School of Engineering, Sun Yat-sen University, Guangzhou, China d Pathology Center, Shanghai General Hospital/Faculty of Basic Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai, China 23 Nanobiomaterials for bone and cartilage repair 33 Byung-Soo Kim A novel monoclonal antibody SMab-2 recognizes endogenous IDH2-R172S of chondrosarcoma Seoul National University Xing Liu 26 Yamagata University School of Medicine Eicosapentaenoic acid attenuates dexamethasone-induced apoptosis by inducing adaptive autophagy via GPR120 in murine bone marrow-derived 34 mesenchymal stem cells Continuous decrease of obturator internus muscle volume after total hip Bo Gao, Liu Yang, Zhuo-Jing Luo arthroplasty Xijing Hospital, the Fourth Military Medical University Dongmin Xu, Hiroshi Koyama, Hiromoto Furuhashi, Shoichi Nishikino, Hoshino Hironobu, Matsuyama Yukihiro 29 Hamamatsu University School of Medicine Proximal fibular osteotomy, an alternative surgery for pain relief and improvement of knee joint function 35 Xiaohu Wanga, Xiaochun Weia, Pengcui Lia, Zhi LVa, Zhaohui Yanga, Min Zhanga, Bin Guided bone regeneration using asymmetrically porous membrane with bio- Zhaoa, Dengfen Zhanga, Lei Weib logical/physical stimulation a The Second Hospital of Shanxi Medical University Jin Ho Lee b The Alpert Medical School of Brown University, Providence, RI, USA Hannam University

http://dx.doi.org/10.1016/j.jot.2016.07.001 2214-031X Titles of other abstracts 139

37 49 TIMP3 regulates osteosarcoma cell migration, invasion and chemotherapeutic A novel bioactive and degradable magnesium screw with polymer coating Xiuguo Han, Tingting Tang developed for osteoporotic fracture fixation a b a a b b Shanghai Jiao Tong University of Medicine Li Tian , Yifeng Sheng , Dick Ho-Kiu Chow , Le Huang , Chi Wu , To Ngai , Ning Tanga, Kwok-Sui Leunga, Ling Qina 38 a Department of Orthopaedics & Traumatology, The Chinese University of Hong Kong MicroRNA-30a downregulation contributes to chemoresistance of osteosarcoma b Department of Chemistry, The Chinese University of Hong Kong cells through activating Beclin-1-mediated autophagy 52 Shuzhong Liua, Lifeng Laob a Intra-articular injection of cross-linked hyaluronic acid-dexamethasone hydrogel Department of Orthopedic Surgery, Peking Union Medical College Hospital, attenuates osteoarthritis: An experimental study in a rat model of osteoarthritis Chinese Academy of Medical Sciences & Peking Union Medical College a a b a b a b Zhiwei Zhang , Xiaochun Wei , Jizong Gao , Yu Zhao , Yamin Zhao , Li Guo , Department of Orthopaedic Surgery, Renji Hospital, Shanghai Jiaotong University Chongwei Chena, c, Zhiqing Duana, Pengcui Lia, Lei Weia, c School of Medicine a Department of Orthopedics, the Second Hospital of Shanxi Medical University 39 b BioRegen Biomedical (Changzhou) Co. Ltd In vivo inhibition of bone morphogenetic protein-2 on breast cancer growth c Department of Orthopedics, Warren Alpert Medical School of Brown University through the PI3K/AKT pathway Shuzhong Liu, Yipeng Wang 53 Department of Orthopaedic Surgery, Peking Union Medical College Hospital, GATA-5 induction defends against oxidative stress-induced apoptotic insults to Chinese Academy of Medical Sciences and Peking Union Medical College rat osteoblasts Ruei-Ming Chena, b, Gong-Jhe Wua, Yi-Ling Lina, b 40 a Taipei Medical University In vivo inhibition of bone morphogenetic protein-2 on hepatocellular carcinoma b d growth through the PI3K/AKT pathway Taipei Medical University Wan-Fang Hospital Shuzhong Liu, Yipeng Wang 54 Department of Orthopaedic Surgery, Peking Union Medical College Hospital, Tailoring the degradation and biological response of a magnesiumestrontium Chinese Academy of Medical Sciences and Peking Union Medical College alloy for potential bone substitute application

41 Peng Wan Intermittent parathyroid hormone enhances fixation of a physiologically loaded Chinese University of Hong Kong tibial implant in ovariectomized mice 56 Xu Yang Two millimeter glenohumeral diametric mismatch does not compromise initial Hospital for Special Surgery fixation of glenoid component

43 Shouchen Dun Correlation of coronal and sagittal balance with functional outcomes in total DePuy Synthes Joint Reconstruction ankle arthroplasty 58 Sarah Johnson-Lynn, Jayasree Ramaskandan, Malik Siddique Genomic analyses reveal rare genetic variants in congenital scoliosis Newcastle upon Tyne Hospitals Trust Feng Zhang 44 Fudan University Biodegradable magnesium interference screws accelerate mineralization of fibrous tissue at the tendon-bone insertion in anterior cruciate ligament 63 reconstruction model of rabbit Pathophysiological role of ADAM8 (a disintegrin and metalloproteinase 8) in Jiali Wang, Jiankun Xu, Patrick Shu-hang Yung, Kaiming Chan, Ling Qin intervertebral disc degeneration Miersalijiang Yasena, b, Yejia Zhanga, Robert Maucka, Maurizio Pacificia, Lachlan Department of Orthopaedics and Traumatology, The Chinese University of Hong a c c a Kong Smith , Greg Anderson , Dessislava Markova , Motomi Enomoto-Iwamoto a University of Pennsylvania 46 b Zhongshan Hospital Fudan University Study of anti-rheumatic effect by cucurbitacin E via modulation of PI3K/Akt/ c Jefferson University Hospital NF-kB pathways Wenxiang Chenga, Qingyun Jiab, Yingping Hua, Peng Zhanga 70 a Translational Medicine R&D Center, Shenzhen Institutes of Advanced Technology, Zn-based biodegradable alloys in orthopaedics Chinese Academy of Sciences Huafang Lia, b, Xinhui Xiea, Yufeng Zhengb, Ling Qina b Department of Orthopedics, Rizhao Hospital of Traditional Chinese Medicine a Musculoskeletal Research Laboratory, Department of Orthopaedics & Traumatology, The Chinese University of Hong Kong, Shatin, Hong Kong, China 47 b State Key Laboratory for Turbulence and Complex System and Department of Icariin incorporated into a porous scaffold promotes reparative osteogenesis Materials Science and Engineering, College of Engineering, Peking University, in vitro and in vivo Beijing 100871, China Huijuan Cao, Shukui Chen, Ming Zhang, Nan Wang, Long Li, Ling Li, Xinluan Wang, Yuxiao Lai, Ling Qin 71 Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences Src siRNA maintains normal bone homestasis during destructive repair process in osteonecrosis 48 Huijuan Caoa, Lizhen Zhengb, Ling Lia, Le Huangb, Cairong Lia, Yuxiao Laia, Xinluan Role of lubricin in Achilles tendinopathy Wanga, b, Ling Qina, b Yu-Long Suna, Jing-Heng Wub, Kai-Nan Anc a Translational Medicine R&D Center, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of a Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences Sciences b Beijing Jishuitan Hospital b Musculoskeletal Research Laboratory, Department of Orthopaedics & c Mayo Clinic Traumatology, The Chinese University of Hong Kong 140 Titles of other abstracts

72 83 Lymphotoxin-a gene polymorphism rs909253 increases susceptibility to chronic Comparative study using touch surgery application for carpal tunnel surgery osteomyelitis in Chinese population Kamil Amera, Kamal Amerc, Taha Mura, Asif Ilyasb Nan Jiang, Bin Yu, Xing-qi Zhao, Cheng-he Qin a Temple University School of Medicine Department of Orthopaedics and Traumatology, Nanfang Hospital, Southern b Thomas Jefferson University Medical College Medical University c UMDNJdRutgers New Jersey Medical School

73 85 Association of vitamin D receptor gene TaqI, BsmI, FokI and ApaI polymorphisms and The infra-patellar fat pad as a source of perivascular stem cells with increased susceptibility of extremity chronic osteomyelitis in Chinese population chondrogenic potential for regenerative medicine Bin Yu, Nan Jiang, Xing-qi Zhao, Cheng-he Qin, Lei Wang Paul Hindlea, b, c, Nusrat Khana, Leela Biant b, Bruno Peaulta, d Department of Orthopaedics and Traumatology, Nanfang Hospital, Southern a MRC Centre for Regenerative Medicine, The University of Edinburgh Medical University b Department of Trauma and Orthopaedic Surgery, The Royal Infirmary of 74 Edinburgh c Diagnostic values of preoperative serum WBC, ESR, CRP, procalcitonin, Academic Department of Military Surgery and Trauma, The Royal Centre for interleukin-6 and tumor necrosis factor-a for extremity chronic osteomyelitis Defence Medicine and their potential influencing factors d University of California in Los Angeles

Bin Yu, Nan Jiang, Cheng-he Qin, Yan-jun Hu 86 Department of Orthopaedics and Traumatology, Nanfang Hospital, Southern Development of an autologous ovine model for perivascular stem cells with GFP Medical University tracking of cells implanted in articular cartilage repair 75 Paul Hindlea, b, c, James Bailya, Leela Biantb, Hamish Simpsonb, Bruno Peaulta, d a Advanced musculoskeletal imaging systems adopted for study of a novel MRC Centre for Regenerative Medicine, The University of Edinburgh, UK bone-targeting delivery system carrying osteopromotive phytomolecule(s) b Department of Trauma and Orthopaedic Surgery, The Royal Infirmary of developed for prevention of estrogen depletion induced osteoporosis Edinburgh, UK Le Huang c Academic Department of Military Surgery and Trauma, The Royal Centre for The Chinese University of Hong Kong Defence Medicine, UK d University of California in Los Angeles, USA 76 87 Induction of CD146 expression in human annulus fibrosus cells for functional repair of annulus rupture A new animal model of tendinopathy e failed tendon healing by hydrogen peroxide Rose G. Longa, b, e, Tomoko Nakaic, e, Daisuke Sakaic, e, Lorin M. Bennekerd, e, James C. Iatridisb, e, Mauro Alinia, e, Sibylle Grada, e, Zhen Lia, e Sai Chuen Fua, Man Yi Yeunga, Christer G. Rolfb, Kai Ming Chana, Leung Kim Hunga a a AO Research Institute Davos, Davos, Switzerland The Chinese University of Hong Kong b Icahn School of Medicine at Mount Sinai, New York, NY, USA b Karolinska Institutet c Tokai University School of Medicine, Isehara, Japan 89 d Department of Orthopaedic Surgery, University of Bern, Bern, Switzerland An innovative, clinically-representative mouse model of periprosthetic joint e Collaborative Research Partner Annulus Fibrosus Rupture Repair Program of AO infection that permits quantification of peri-implant bacterial load and in vivo Foundation, Davos, Switzerland biofilm formation Alberto Carlia, Samrath Bhimania, Xu Yanga, Vinicius Ladeira Craveiroa, Matthew 78 Shirleya, Karen de Mesy Bentleyb, Frederick Patrick Rossa, Mathias Bostroma The promoting effects of icariin on osteogenic differentiation and maturation a Hospital for Special Surgery, NY, USA of osteoblasts depend on primary cilia-related cAMP-PKA signaling b University of Rochester, NY, USA Wegui Shia, Yan-Fang Xiea, Jian Zhoua, Yuhai Gaoa, Huiping Mab, Shaofeng Lia, Xueyan Lic, Jufang Wangd, Cory Xiane, Keming Chena 90 a Institute of Orthopaedics, Lanzhou General Hospital, Lanzhou Command of CPLA, The mechanism of NLRs in macrophage induced aseptic joint loosening by wear Lanzhou 730050, People’s Republic of China particles in vitro b Department of Pharmacy, Lanzhou General Hospital, Lanzhou Command of CPLA, Yue Ding, Shixun Li, Chi Zhangchi, Changchuan Li, Huiyong Shen Lanzhou 730050, People’s Republic of China Memorial Hospital of Sun Yat-sen University c School of Life Sciences and Engineering, Lanzhou University of Technology, 91 Lanzhou 730050, People’s Republic of China d The mechanism of SHP in macrophage induced aseptic joint loosening by wear Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000, particles in vitro People’s Republic of China Yue Ding, Chi Zhang, Shixun Li, Changchuan Li, Junxiong Qiu, Huiyong Shen e Sansom Institute for Health Research, School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, SA 5001, Australia Memorial Hospital of Sun yat-sen University 92 79 The critical role of mesenchymal progenitors in initiating the secondary Pulsed electromagnetic fields stimulate osteogenic differentiation by increasing ossification center at the epiphyseal cartilage via VEGF signaling pathway BMPRII expression at the cilium base of osteoblasts a, b a a b b a a a a a a Wei Tong , Haoruo Jia , Xiaoyuan Ma , Shuhua Yang , Zengwu Shao , Hongtao Yanfang Xie , Wengui Shi , Jian Zhou , Yuhai Gao , Shaofeng Li , Qingqing Fang , Tianb, Xianzhe Liub, Ling Qina Minggang Wangb, Huiping Mac, Jufang Wangd, Cory Xiane, Keming Chena a a Department of Orthopaedic Surgery, Perelman School of Medicine, University of Institute of Orthopaedics, Lanzhou General Hospital, Lanzhou Command of CPLA, Pennsylvania, Philadelphia, PA 19104, United States Lanzhou 730050, People’s Republic of China b b Department of Orthopaedic Surgery, Union Hospital, Tongji Medical School of Life Sciences and Engineering, Lanzhou University of Technology, College, Huazhong University of Science and Technology, Wuhan, 430022 Hubei, Lanzhou 730050, People’s Republic of China China c Department of Pharmacy, Lanzhou General Hospital, Lanzhou Command of CPLA, Lanzhou 730050, People’s Republic of China 93 d Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000, Post-traumatic osteoarthritis initiates with a rapid decline in the People’s Republic of China nanomechanical strength of cartilage surface caused by matrix breakdown a, b c c b a b e Sansom Institute for Health Research, School of Pharmacy and Medical Sciences, Wei Tong , Basak Doyran , Han Lin , Hongtao Tian , Haoruo Jia , Shuhua Yang , University of South Australia, Adelaide, SA 5001, Australia Zengwu Shaob, Xianzhe Liub, Ling Qina Titles of other abstracts 141 a Department of Orthopaedic Surgery, Perelman School of Medicine, University of 109 Pennsylvania, Philadelphia, PA 19104, United States Kinematics and load-sharing of an anterior thoracolumbar spinal recon- b Department of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong struction construct with PEEK rods: An in vitro biomechanical study University of Science and Technology, Wuhan, 430022 Hubei, China Qingan Zhu c School of Biomedical Engineering, Science, and Health Systems, Drexel Univer- Nanfang Hospital, Southern Medical University, China sity, Philadelphia, PA 19104, United States 110 95 Effect and prognostic factors of laminoplasty for cervical myelopathy with an A Clivus plate fixation for reconstruction of ventral defect of the cranio- occupying ratio greater than 50% vertebral junction: A novel fixation device for craniovertebral instability Guang Dong Chen, Hui Lin Yang, Zong Ping Luo Wei Ji, Zhiping Huang, Ganggang Kong, Xiuhuan Wu, Jianting Chen, Qingan Zhu Department of Orthopedic Surgery of the 1st Affiliated Hospital and Nanfang Hospital, Southern Medical University, China Orthopedic Institute of Soochow University, Suzhou, Jiangsu, China 111 96 Low magnitude high frequency vibration (LMHFV) accelerates the foot wound of Comparison of the degradation of calcium alginate beads combined with streptozotocin-induced diabetic rats chondrocytes in vivo and in vitro Oi ling Yu, Sui Leung Kwok, Kwok Pui Fung, Wing Hoi Cheung Yu Zhaoa, b, Wangping Duana, b, Xiaochun Weia, b, Zhiqing Duana, b, Ruipeng Zhaoa, b The Chinese University of Hong Kong, Hong Kong a Second Affiliated Hospital of Shanxi Medical University b Shanxi Key Laboratory of Bone and Soft Tissue Injury Repair 112 Methylation-mediated silencing of miR-124 facilitates chondrogenesis by 97 targeting NFATc1 under hypoxic conditions Percutaneous kyphoplasty for Kummell’s disease with severe spinal canal Ming Gonga, Tangzhao Liangb, Song Jinc, Xuejun Daia, Zhiyu Zhoua, Manman Gaoa, stenosis Sheng Huanga, Jiaquan Luoa, Liangping Lia, Lijin Zoud, Xuenong Zoua Guang Dong Chen, Hui Lin Yang, Zong Ping Luo a Guangdong Provincial Key Laboratory of Orthopaedics and Traumatology, Department of Orthopedic Surgery of the 1st Affiliated Hospital and Orthopaedic Research lnstitute/Department of Spinal Surgery, The First Orthopedic Institute of Soochow University, Suzhou, Jiangsu, China Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, P. R. China 101 b Department of Orthopedic Surgery, The Third Affiliated Hospital of Sun Yat-sen Delivery of BMP-2 from acrylic bone cement to encourage regenerative bone University, 510080 Guangzhou, P. R. China repair around cemented joint replacements c Department of Spinal Surgery, The Fourth People’s Hospital of Shenzhen (Futian a a b c Wayne Nishio Ayre , Rachel J. Waddington , Samuel L. Evans , Deborah J. Mason , Hospital), Shenzhen, 518033, P. R. China d e f g Bronwen Evans , James C. Birchall , Rhidian Morgan-Jones , Stephen P. Denyer , d Alastair J. Sloana Department of Surgery, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, P. R. China a School of Dentistry, Cardiff University, UK b School of Engineering, Cardiff University, UK 114 c School of Biosciences, Cardiff University, UK Mechanical vibration alleviates the decrease of bone quantity and bone quality d School of Medicine, Cardiff University, UK of leptin receptor-deficient db/db mice by promoting bone formation and inhibiting bone resorption e School of Pharmacy and Pharmaceutical Sciences, Cardiff University, UK Da Jing, Mingming Zhai, Shichao Tong, Erping Luo, Zhuojing Luo f Cardiff & Vale University Health Board, Cardiff, UK Fourth Military Medical University, China g School of Pharmacy and Biomolecular Sciences, University of Brighton, UK

102 115 Anatomical heterogeneity of canine digit annular ligament Low-level mechanical vibration promotes osteogenesis and osseointegration of porous titanium implants in the repair of long bone defects Fang Yuan, Hui-Hui Zhang, Yu-Long Sun Mingming Zhai, Shichao Tong, Guanghao Shen, Kangning Xie, Erping Luo, Da Jing ShenZhen Institutes of Advanced Technology, Chinese Academy of Sciences The Fourth Military Medical University, China 103 118 Metallophobia: Our understanding of ALTR Dynamic frequency of blood CD4DCD25D regulatory T cells in rats with Masahiro Hasegawa, Toshio Yamaguchi, Hironori Unno, Yoshiaki Suzuki, Shine Tone, collagen-induced arthritis Naoya Ito, Akihiro Sudo Tingyu Wanga, Zhigui Jina, Feihua Wua, Yunwu Lia, Tingting Tangb Mie University Graduate School of Medicine a Department of Pharmacy, Shanghai Ninth People’s Hospital, Shanghai Jiaotong 104 University School of Medicine In vivo biochemical tests of a novel PLGA/TCP/MG porous scaffold b Shanghai Key Laboratory of Orthopaedic Implants, Department of Orthopaedic manufactured by 3D printing Surgery, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine Ye Lia, b, c, Long Lia, Huijuan Caoa, Cairong Lia, Xinluan Wanga, c, Ling Qina, c, Yuxiao Laia 119 a Centre for Translational Medicine Research and Development, Shenzhen Institutes of Advanced Technology Study on the delayed cyclical dynamic compressive load on mouse marrow mesenchymal stem cells (MSCs) chondrogenic in 3D culture b Shenzhen College of Advanced Technology, University of Chinese Academy of Sciences, Shenzhen Yongliang Zhao, Yaxun Men, Ziquan Yang c Musculoskeletal Research Laboratory, Department of Orthopaedics and The Second Hospital of Shanxi Medical University, China Traumatology, Chinese University of Hong Kong 120 105 Experimental study on centrifugal force stimulates different stages of mouse Hereditary diseases of locomotor system bone marrow mesenchymal stem cells to chondrocytes Peiqiang Su Yongliang Zhao, Gang Wang, Ziquan Yang The First Affiliated Hospital of Sun Yat-sen University, China The Second Hospital of Shanxi Medical University, China 142 Titles of other abstracts

121 b John A. Paulson School of Engineering and Applied Sciences, Harvard University, Prophylactic ketogenic metabolism inhibits histone deacetylase and Cambridge, MA 02138, US suppression of oxidative stress after spinal cord injury in rats 135 Qingan Zhu, Xiaomeng Wang, Qi Liu, Jian Zhou, Ganggang Kong, Xiuhua Wu Bone marrow stromal cell sheet contains M2 phenotype macrophages and Nanfang Hospital, Southern Medical University the sheet transplantation promotes axonal regeneration after completely transected spinal cord injury in rats 123 Akinori Okudaa,b, Noriko Hayashi-Horiib, Takamasa Shimizua, Hideki Shigematsua, Comparison of adductor canal block with femoral nerve block following total Eiichiro Iwataa, Yasuhiko Morimotoa, Keisuke Masudaa, Manabu Akahanec, Mayumi knee arthroplasty: A systematic review with meta-analysis NIshib, Yasuhito Tanakaa Xing-qi Zhao, Nan Jiang, Bin Yu a Department of Orthopedic Surgery, Nara Medical University Department of Orthopaedics and Traumatology, Nanfang Hospital, Southern b Department of Anatomy and Cell Biology, Nara Medical University Medical University c Department of Public Health, Health Management and Policy, Nara Medical 124 University Kingella kingae-associated pediatric osteoarticular infections: An overview of 136 566 reported cases Tendon differentiation and regeneration: Implications for clinical practice Bin Yu, Mohammed Al-Qwbani, Nan Jiang Hongwei Ouyang Department of Orthopaedics and Traumatology, Nanfang Hospital, Southern Medical University Zhejiang University

125 138 Study of the influence of sarcopenia on osteoporotic fracture healing in a 2, 6-Pyridinedicarboxaldehyde cross-linked PEI 18kDa for delivering microRNA- senescence accelerated mouse (SAMP8) model 221/222 for rat sciatic nerve regeneration Ning Zhang, Kwok-Sui Leung, Simon Kwoon-Ho Chow, Wing-Hoi Cheung Jialin Song, Cunyi Fan Department of Orthopaedics and Traumatology, Faculty of Medicine, The Chinese Shanghai Jiao Tong University Affiliated Sixth People’s Hospital University of Hong Kong, Hong Kong 139 126 Bacterial inhibition potential and osteogenic activity of 3D-printed bone Down-regulation of Mkx, Egr1 and TGF-b1 expression in high glucose-treated substitutes tendon cells Tingting Tang Yu-Fu Wua, Yuan-Hung Chaoa, b, Hsin-Kuo Wanga, Jui-Sheng Sunc, d a Shanghai Key Laboratory of Orthopaedic Implants, Department of Orthopedic School and Graduate Institute of Physical Therapy, College of Medicine, National Surgery, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Taiwan University, Taipei, Taiwan Medicine b Department of Physical Therapy, National Taiwan University Hospital Chu-Tung Branch, Hsinchu County, Taiwan 141 c Department of Orthopedics, National Taiwan University Hospital, Taipei, Taiwan The development and optimization of coculture scaffold-free cell sheet of neural stem/progenitor cells and bone marrow stromal cells d Department of Orthopedics, College of Medicine, National Taiwan University, Taipei, Taiwan Keisuke Masudaa, Akinori Okudaa, b, Takamasa Shimizua, Hideki Shigematsua, Eiichiro Iwataa, Yasuhiko Morimotoa, Manabu Akahaneb, Yasuhito Tanakaa 127 a Department of Orthopedic Surgery, Nara Medical University The role of mast cells in the inflammatory phase of bone healing b Department of Public Health, Health Management and Policy, Nara Medical Jose Ramirez Garcia Luna, Yazeed Al-Saran, Timothy Wong, Ailian Li, Mira University Abou-Rjeili, Chan Gao, Janet Henderson, Paul Martineau McGill University 142 Preparation and properties of calcium phosphate cement incorporated with N- 128 acetylcysteine loading silk fibroin microspheres Biomechanical study on unilateral CLP patient of simulated post-op protraction Lei Jiang, Tao Feng, Xuesong Zhu, Huilin Yang after maxillary fissure repair-based on finite element analysis The First Affiliated Hospital of Soochow University Diya Maa, Hui Lina, Zhigang Liangb, Lening Lia, Liang Yangb, Li Sze Chowa, Lin Shia, a Defeng Wang 143 a The Chinese University of Hong Kong 8-prenylgenistein, a derivative of genistein, exerted osteoprotective effects b The Second People’s Hospital of Shenzhen without uterotropic activity a b b a b 129 Yan Zhang , Li-Ping Zhou , Ming-Xian Ho , Yong-Jun Wang , Man-Sau Wong a Combined effects of osteoporosis and instability on intervertebral disc Longhua Hospital, Shanghai University of Traditional Chinese Medicine degeneration in rats b The Hong Kong Polytechnic University a b b b b Qi Liu , Xiaomeng Wang , Ganggang Kong , Xiuhua Wu , Zhiping Huang , Qingan 144 Zhub a Mesenchymal stem cells regulate mechanical properties of human degenerated Guangdong Rehabilitation Hospital for Industrial Injury nucleus pulposus cells through SDF-1/CXCR4/AKT axis b Nanfang Hospital, Southern Medical University Ming-Han Liu, Yue Zhou 131 Xinqiao Hospital, Third Military Medical University In vivo evaluation of the anti-infection potential of gentamicin-loaded nano- 145 tubes on titania implants The differential effect of matrix elasticity on cartilage endplate-derived stem Ying Yang, Tingting Tang cells behavior during disc degeneration Shanghai Key Laboratory of Orthopaedic Implants, Department of Orthopedic Ming-Han Liu, Yue Zhou Surgery, Shanghai Ninth People’s Hospital, China Xinqiao Hospital, Third Military Medical University 133 146 Injectable stem cell-laden hydrogel microspheres for osteogenic regeneration Cellular mechanical properties reflect the differentiation potential of nucleus Wenguo Cuia, b, Xin Zhaob, David Weitzb, Bin Lia, Huiling Yanga pulposus-derived progenitor cells a Department of Orthopedics, the First Affiliated Hospital of Soochow University, Ming-Han Liu, Yue Zhou Orthopedic Institute, Soochow University, 708 Renmin Road Suzhou, Jiangsu Xinqiao Hospital, Third Military Medical University 215006, China Titles of other abstracts 143

150 173 Manual therapy for hip osteoarthritis: A systematic review and meta-analysis Blocking the SDF-1/CXCR4 signaling pathway attenuates the destruction of Qiong Wang aggrecan in PTOA rat model Longhua hospital Weiwei Lu, Yuting Wang, Zhentao Lv, Jinming Zhang, Anmin Chen Tongji Hospital of Tongji Medical College, Huazhong University of Science and 151 Technology A novel and undefined subtype of congenital scoliosis: TBX6-associated congenital scoliosis (TACS) 175 Nan Wua, b, c, Jiaqi Liua, b, Zhenlei Liua, b, Yuzhi Zuoa, b, Weisheng Chena, b, Sen Liua, b, Mesenchymal stem cells promote functional recovery of hemisection spinal Pengfei Liud, James Lupskid, e, Feng Zhangf, Zhihong Wub, c, g, Guixing Qiua, b, c cord injury by regulating the polarization of macrophage subsets a Beijing Key Laboratory for Genetic Research of Skeletal Deformity, China Zhan Peng, Xingzhi Liu, Xiaojing Ju, Huiling Yang, Liang Chen, Qin Shi b Department of Orthopaedic Surgery, Peking Union Medical College Hospital, Orthopedic Department, The First Affiliated Hospital of Soochow University, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing Orthopedic Institute, Soochow University, Suzhou, China 100730, China 176 c Medical Research Center of Orthopaedics, Chinese Academy of Medical Sciences Improved osteogenesis and up-regulated immunogenicity in human placenta- d Department of Molecular and Human Genetics, Baylor College of Medicine, derived mesenchymal stem cells primed with osteogenic induction medium Houston, TX 77030, USA Xuejie Fua, Huilin Yanga, Hui Zhanga, Guichao Wanga, Ke Liua, Qiaoli Gua, Yunxia e Human Genome Sequencing Center, Department of Pediatrics and Texas Chil- Taoa, Guangcun Chenb, Xiaohua Jiangc, Gang Lid, Yanzheng Gua, Qin Shia drens Hospital, Baylor College of Medicine, Houston, TX 77030, USA a Orthopedic Department, The First Affiliated Hospital of Soochow University, f State Key Laboratory of Genetic Engineering and Ministry of Education Key Orthopedic Institute, Soochow University, Suzhou, China Laboratory of Contemporary Anthropology, Collaborative Innovation Center of b Key Laboratory of Nano-Bio Interface, Division of Nanobiomedicine and i-Lab, Genetics and Development, School of Life Sciences, Fudan University, Shanghai Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, 200438, China Suzhou, China g Department of Central Laboratory, Peking Union Medical College Hospital, Peking c Epithelial Cell Biology Research Center, School of Biomedical Sciences, Faculty of Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, China Medicine, The Chinese University of Hong Kong, Hong Kong SAR, PR China 154 d Department of Orthopaedics & Traumatology, Stem Cells and Regenerative Sclerostin-antibody promotes femoral fracture healing in ovariectomised rats Medicine Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China Yang Liu, Yunfeng Rui, Tinyan Cheng, Shuo Huang, Liangliang Xu, Fanbiao Meng, Yukwai Lee, Ting Zhang, Nan Li, Gang Li 177 Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong The effect and regulatory mechanism of miR-424 on the proliferation and osteogenic differentiation of human adipose tissue-derived stem cells under 157 oxidative stress Human fetal mesenchymal stem cell secretome enhances bone consolidation in Liangping Li, Jiaquan Luo, Sheng Huang, Qihua Qi, Zemin Ling, Manman Gao, Zhiyu distraction osteogenesis Zhou, Xuenong Zou Jia Xu, Bin Wang, Yuxin Sun, Jinfang Zhang, Gang Li The First Affiliated Hospital of Sun Yat-sen University The Chinese University of Hong Kong Shenzhen Research Institute 178 158 Risk factors related to one-year mortality in displaced intracapsular hip Staphylococcal enterotoxin C2 expedites bone consolidation during distraction fracture patients osteogenesis Jianghui Qin Jia Xu, Tianyi Wu, Yuxin Sun, Jinfang Zhang, Gang Li The Chinese University of Hong Kong The Chinese University of Hong Kong Shenzhen Research Institute 179 159 Ketogenic diet decreases both cancellous and cortical bone mass of the femur Is mini-plate fixation superior to suture suspensory fixation in cervical in mice laminoplasty? Xiuhua Wu, Zucheng Huang, Xiaomeng Wang, Qi Liu, Qingan Zhu Qihua Qi, Liangping Li, Jiaquan Luo, Sheng Huang, Zhiyu Zhou, Manman Gao, Nanfang Hospital, Southern Medical University Xuenong Zou 183 The First Affiliated Hospital Of Sun Yat-Sen University Biomechanical study of using translaminar facet screw coupled with unilateral 161 pedicle screw in transforaminal lumbar interbody fusion Retrieval analyses of implants: A case study of spinal dynamic stabilization Wen Zhang, Jianqiang Mo, Zongping Luo devices Department of Orthopedics, The First Affiliated Hospital of Soochow University, Kai Zhang Orthopedic Institute, Medical College, Soochow University, Suzhou, Jiangsu, National Engineering Research Center for Biomaterials, Sichuan University People’s Republic of China. 184 162 The correlation study performed between rank-l serum level and other Bone matrix materials and its application to bone repair and regeneration infection indicators and culture results in osteomyelitis model of mice Xuenong Zou Volkan O¨ztuna The First Affiliated Hospital of Sun Yat-sen University Mersin University School of Medicine 164 185 Introducing Wnt16 attenuates the severity of osteoarthritis Dexamethasone impairs bone formation via KLF15-Wnt/b-catenin pathway Wenxue Tonga, Kinglun Kingston Makb, Ling Qina Yajun Yang, Jin Li, Wenxiu Lai, Yuyu Liu, Shiying Luo, Liao Cui a Prince of Wales Hospital, The Chinese University of Hong Kong Department of Pharmacology, Guangdong Key Laboratory for R & D of Natural b School of Biomedical Sciences, The Chinese University of Hong Kong Drugs, Guangdong Medical University

166 186 Tendon-derived stem cell sheet enhances the repair of injured rotator cuff Inhibition of connexin 43 prevents trauma-induced heterotopic ossification Jiankun Xu Bing Tu, Cunyi Fan The Chinese University of Hong Kong Shanghai Jiaotong University Affiliated Sixth People’s Hospital 144 Titles of other abstracts

187 200 Biosynthesis of LMP-1 gene-transfected cells on natural scaffolds used to pro- Workshop: Periprosthetic Joint Immunology: Can we overcome osteolysis? mote bone regeneration Yukihide Minoda Junxuan Ma, Zhiyu Zhou, Manman Gao, Zemin Ling, Qihua Qi, Xuenong Zou Osaka City University Graduate School of Medicine Orthopaedic Research Institute 201 189 Direct repair of lumbar pars interarticular defects by utilizing intraoperative The effects of orientation of lumbar facet joints on facet joint contact forces: O-arm based navigation and microendoscopic technique An in vitro biomechanical study Jian Wang Xiang Liu, Zhiping Huang, Ruozhou Zhou, Jixing Wang, Qingan Zhu Xinqiao Hospital of Chongqing Nanfang Hospital, Southern Medical University 202 190 Effect of percutaneous anterior screw fixation for odontoid fractures on atlantoaxial rotation Activation of mTORC1 in B lymphocytes promotes osteoclast formation via regulation of beta-catenin and RANKL/OPG Jian Wang Song Xu Xinqiao Hospital of Chongqing Department of Cell Biology, Southern Medical University 203

192 Predicating value of short tau inversion recovery MRI in early painful osteoporotic vertebral fractures treated by percutaneous kyphoplasty Is surgical treatment better than conservative treatment for primary patellar dislocations? A meta-analysis of randomized controlled trials Jian Wang Sheng-nan Wang, Bin Yu, Cheng-he Qin Xinqiao Hospital of Chongqing Department of Orthopaedics and Traumatology, Nanfang Hospital 204 Minimally invasive surgery transforaminal lumbar interbody fusion for high- 193 grade spondylolisthesis in adult patients Management of pediatric forearm torus fractures: A systematic review and Jian Wang meta-analysis. Xinqiao Hospital of Chongqing Nan Jiang, Bin Yu 205 Nanfang Hospital, Southern Medical University Application of distal-radius positioned hinged external fixator in complete open 194 release for severe elbow stiffness IL-1b irreversibly inhibits tenogenic differentiation and alters metabolism in Yi Zhou, Jiang-yu Cai, Shuai Chen, Shen Liu, Wei Wang, Cunyi Fan injured tendon-derived progenitor cells in vitro Shanghai Jiao Tong University Affiliated Sixth People’s Hospital Kai-rui Zhang, Bin Yu 206 Department of Orthopaedics and Traumatology, Nanfang Hospital, Southern Medical University Reconstruction of medial collateral ligament defects with flexor-pronator fascia patch in complete open release of stiff elbows 195 Shuai Chen, Cunyi Fan Pigmented villonodular synovitis: A retrospective multicenter study of 237 cases Shanghai Jiao Tong University Affiliated Shanghai Sixth People’s Hospital

Guo-ping Xie, Bin Yu 208 Department of Orthopaedics and Traumatology, Nanfang Hospital, Southern Natural product pectolinarigenin inhibits osteosarcoma growth and metastasis Medical University via SHP1-mediated STAT3 signaling inhibition

196 Tao Zhang, Fei Yin, Zhuoying Wang, Yingqi Hua, Zhengdong Cai Treatment with recombinant lubricin attenuates osteoarthritis by positive Department of Orthopaedics, Shanghai Bone Tumor Institute, Shanghai General feedback loop between articular cartilage and subchondral bone in Hospital ovariectomized rats 211 Zhuang Cui, Bin Yu Assessing volumetric bone mineral density in adolescent idiopathic scoliosis: Department of Orthopaedics and Traumatology, Nanfang Hospital, Southern Quantitative computed tomography vs high-resolution peripheral quantitative Medical University computed tomography e A pilot study Elisa M.S. Tama,f,FionaW.P.Yua,b,VivianW.Y.Hunga,b, Lin Shic,LingQina,b,Bobby 197 K.W. Nga,f,WinnieC.W.Chud, James Griffithd,JackC.Y.Chenga,e,f, Tsz-Ping Lama,e,f Aucubin prevents interleukin-1 beta induced inflammation and cartilage a Department of Orthopaedics & Traumatology, The Chinese University of Hong matrix degradation via inhibition of NF-kB signaling pathway in rat articular Kong, Hong Kong chondrocytes b Bone Quality and Health Centre, Department of Orthopaedics & Traumatology, Sheng-nan Wang, Bin Yu The Chinese University of Hong Kong, Hong Kong Department of Orthopaedics and Traumatology, Nanfang Hospital, Southern c Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Medical University Hong Kong 198 d Department of Imaging & Interventional Radiology, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong Eucommia ulmoides Oliv. bark aqueous extract inhibits osteoarthritis in a rat model of osteoarthritis e SH Ho Scoliosis Research Laboratory, The Chinese University of Hong Kong, Hong Kong Guo-ping Xie, Bin Yu f Joint Scoliosis Research Center of the Chinese University of Hong Kong and Nanjing University Department of Orthopaedics and Traumatology, Nanfang Hospital, Southern Medical University 212

199 Using calcium and vitamin D supplementation to control disease progression in adolescent idiopathic scoliosis (AIS)dA randomised double-blinded placebo- Induction of chondrogenesis and inhibition of angiogenesis are coordinately controlled trial regulated by miRNA of mesenchymal stem cells in ECM materials under hypoxia Elisa M.S. Tama, b, Benjamin Hon Kei Yipa, Fiona Wai Ping Yua, b, Gene Chi Wai Mana, d, a, b b b b b Shaoming Chen , Manman Gao , Zhiyu Zhou , Jiabi Liang , Ming Gong , Jiacheng Wayne Y.W. Leea, d, Kwong Man Leeb, c, Bobby Kin Wah Nga, b, d, Jack Chun Yiu b b b b b Ye , Tangzhao Liang , Xuejun Dai , Lijin Zou , Xuenong Zou Chenga, b, d, Tsz-Ping Lama, b, d a The Fifth Affiliated Hospital of Sun Yat-sen University a Department of Orthopaedics and Traumatology, The Chinese University of Hong b The First Affiliated Hospital of Sun Yat-sen University Kong, Hong Kong Titles of other abstracts 145 b Joint Scoliosis Research Center of the Chinese University of Hong Kong and 227 Nanjing University The use of SHP-2 gene transduced bone marrow mesenchymal stem cells to c Lee Hysan Clinical Research Laboratory, Faculty of Medicine, The Chinese promote osteogenic differentiation and bone defect repair in rat University of Hong Kong, Hong Kong Dapeng Fan, Shen Liu, Zhiwei Li, Cunyi Fan d SH Ho Scoliosis Research Laboratory, The Chinese University of Hong Kong, Hong Shanghai Jiaotong University Affiliated Sixth People’s Hospital Kong 230 213 Effect of gender, body mass index and quadriceps femoris muscle strength on Chondrocyte FGFR3 regulates bone mass by promoting osteogenesis patellar tendon mechanical properties Xuan Wen, Nan Su, Lin Chen Serkan Tas‚a, Seval Yılmaza, Mehmet Ruhi Onurb, Feza Korkusuzc Third Military Medical University a Hacettepe University, Beytepe Hospital, Ankara, Turkey b 214 Hacettepe University, School of Medicine, Department of Radiology, Ankara, Turkey c Exogenous fibroblast growth factor 9 attenuates cartilage degeneration and Hacettepe University, School of Medicine, Department of Sports Medicine, aggravates osteophyte formation in post-traumatic osteoarthritis Ankara, Turkey Siru Zhou, Zuqaing Wang, Yangli Xie, Yue Shen, Xiaolan Du, Lin Chen 232 Third Affiliated Hospital of Third Military Medical University The potential of cell sheets for cartilage regenerative therapy Masato Sato 215 Tokai University School of Medicine Repair of brachioradialis origin on the distal site of epicondyle during elbow arthrolysis: Direct effect on the strength of upper extremities 233 Wei Chen, Cunyi Fan Achilles tendon thickness but not stiffness decreases after intensive exercise: A Shanghai Sixth People’s Hospital pilot study Serkan Tas‚a, Feza Korkusuzb 216 a Hacettepe University, Beytepe Hospital, Ankara, Turkey A micro-CT-based finite element analysis of lumbar spinal osteoporosis due to b Hacettepe University, School of Medicine, Department of Sports Medicine, ketogenic diet in mice Ankara, Turkey Xiuhua Wu, Junhao Liu, Xiaomeng Wang, Zucheng Huang, Wei Ji, Qingan Zhu 235 Nanfang Hospital, Southern Medical University Screening of anti-osteoporosis effective component of Sargassum integer- 217 rimum in vitro LincRNA-Y modulates osteogenic differentiation via Wnt/b-catenin pathway Zhongqin Gong, Shuhui Li, Yanlong Liang, Liao Cui, Yi Liu Lu Fenga, b, Bin Wanga, b, Jinfang Zhanga, b, Gang Lia, b Department of Pharmacology, Guangdong Key Laboratory for Research and Development of Natural Drugs, Guangdong Medical University a The Chinese University of Hong Kong Shenzhen Research Institute, Shenzhen, PR China 236 b Department of Orthopaedics & Traumatology, Lui Che Woo Institute of Innovative Study of different proportions of tanshinol and salvianolic acid B isolated from Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong Salvia miltiorrhiza utility aqueous extract on osteoblast differentiation SAR, PR China Shuhui Li, Zhongqin Gong, Yanlong Liang, Wenxiu Lai, Minqun Du, Liao Cui 218 Department of Pharmacology, Guangdong Key Laboratory for Research and Deletion of Axin1 in osteoblast progenitor cells leads to delayed endochondral Development of Natural Drugs, Guangdong Medical University bone formation through inhibition of osteoclast formation 237 a, b a, b a, b d b, c Bing Shu , Yongjian Zhao , Chunchun Xue , Rong Xie , Yongjun Wang , Type II diabetes alters macrophage polarization and collagen deposition during d Di Chen tendon healing a Longhua Hospital, Shanghai University of TCM Jessica Ackerman, Michael Geary, Caitlin Orner, Alayna Loiselle b Spine Research Institute, Shanghai University of TCM University of Rochester Medical Center c School of Rehabilitation Science, Shanghai University of TCM 238 d Rush University Downregulation of FABP4 promotes osteoclast formation and function by acting 219 PPAR-g signaling A unique multi-planar external fixator developed for hip distraction Yuting Wang, Yonghui Dong, Chao Song, Weiwei Lu, Kun Chen, Hui Liu, Xuejun Wing Ho Chaua, Yuk Sun Chenga, Fuk Tat Makb, Kin Sum Cheunga, Ling Qina, Bobby Zhang, Anmin Chen Kin Wah Nga Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong a Department of Orthopaedics & Traumatology, The Chinese University of Hong University of Science and Technology Kong, Shatin, Hong Kong 240 b Department of Electronic Engineering, The Chinese University of Hong Kong, Effect of metformin on bone mineral density and microstructure of proximal Shatin, Hong Kong tibias in type 2 diabetic GK rats 222 Yanlong Liang, Shuhui Li, Minqun Du, Wenxiu Lai, Liao Cui Vertebral artery occlusion and recanalization after cervical facet dislocation Department of Pharmacology, Guangdong Key Laboratory for Research and Zhengfeng Zhang Development of Natural Drugs, Guangdong Medical University, Zhanjiang, Guang- dong 524023, China Xinqiao Hospital 242 223 Adipose-derived stem cells alleviate osteoporosis by enchancing osteogenesis Anterior pedicle spreader reduction for unilateral cervical facet dislocation and inhibiting adipogenesis in a rabbit model Zhengfeng Zhang Peng Zhang, Guangpeng Liu Xinqiao Hospital Shandong Provincial Hospital affiliated to Shandong University 224 243 Anterior spinal artery occlusion on computed tomography angiography in Expression of high mobility group box 1 protein predicts a poorer prognosis for severe cervical compressive myelopathy patients with osteosarcoma Zhengfeng Zhang Peng Zhang, Ping Liu Xinqiao Hospital Shandong Provincial Hospital affiliated to Shandong University 146 Titles of other abstracts

244 d Department of Computer Science, University of Saskatchewan, Saskatoon SK, Canada Investigating time point for stimulation of vascular endothelial growth factor e Department of Electrical and Computer Engineering, University of British and mesenchymal stem cell on bone formation in severe immunodeficiency Columbia, Vancouver BC, Canada mice 257 Chris Dreyera, Niklas Rye Joergensenb, Soeren Overgaarda, Ming Dinga Clock gene Bmal1 modulates cartilage homeostasis in human cartilage by a Orthopaedic Research Laboratory, Department of Orthopaedics and Traumatol- crosstalk with Sirt1 ogy, Odense University Hospital, Institute of Clinical Research, University of Southern Denmark Wei Yang, Xiaomin Kang, Xinxin Jin, Zhuang Qian, Tianping Xie, Shufang Wu b Research Center for Ageing and Osteoporosis, Glostrup, Denmark The First Affiliated Hospital of Xi’an Jiaotong University 262 245 Parathyroid hormone activates PLC-independent protein kinase C signaling Genome-wide association meta-analyses identified 1q43 and 2q32.2 for hip pathway via both PKA dependent and independent mechanisms Ward’s triangle areal bone mineral density Dehong Yang Wen-Zhu Hua, b, Yu-Fang Peib, c, Shu Rand, Yong Lind, Hui Shene, Qing Tiane, Hong- Wen Denge, Lei Zhanga, b Nanfang Hospital Southern Medical University a Center for Genetic Epidemiology and Genomics, School of Public Health, Medical 264 College of Soochow University, Jiangsu, P. R. China PLC-independent PKC signaling selective PTH peptide enhances bone formation b Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Dehong Yang Diseases Nanfang Hospital Southern Medical University c Department of Epidemiology and Health Statistics d Center of System Biomedical Sciences, University of Shanghai for Science and 265 Technology, Shanghai, P. R. China The effects of LPS on endochondral bone development of mice in in vitro bone e Department of Biostatistics and Bioinformatics, Tulane University School of Public culture Health and Tropical Medicine, New Orleans, Louisiana, USA Keyuan Sun, Jing Yang, Wei Xu, Quan Wang, Xiaolan Du, Lin Chen

249 Center of Bone Metabolism and Repair, Department of Rehabilitation Medicine, State Key Laboratory of Trauma, Burns and Combined Injury, Trauma Quantification of time-dependent microdamage accumulation during fatigue Center, Institute of Surgery Research, Daping Hospital, Third Military Medical loading in rat long bone based on a novel mechanical loading system University Xuhui Zhang, Zedong Yan, Xiyu Liu, Mingming Zhai, Da Jing, Erping Luo 266 The Fourth Military Medical University Suppression of G protein-coupled estrogen receptor-1(GPER-1) enhances 250 osteogenic-differentiation in murine bone marrow mesenchymal stem cells Leukocyte mitochondrial DNA copy number and telomere length in patients Je-Ken Chang, Shu-Chun Chuang, Mei-Ling Ho with knee osteoarthritis Orthopaedic Research Center and Department of Orthopaedics, Kaohsiung Dong Zhan, Aree Tanavalee, Pongsak Yuktanandana, Thitiya Poonpet, Sittisak Medicine University Honsawek 269 Department of Biochemistry, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand Differential expression of LBX1 in paravertebral muscles and vertebra of Chinese patients with adolescent idiopathic scoliosis: A preliminary study 251 Gene Chi Wai Mana, d, Nelson Leung Sang Tangb, d, Wayne Yuk Wai Leea, d, Jiajun GPR120: A bi-potential mediator to modulate the osteogenic and adipogenic Zhanga, d, Bobby Kin Wah Nga, d, Leilei Xuc, d, Yong Qiuc, d, Jack Chun Yiu Chenga, d differentiation of BMMSCs a Department of Orthopedics and Traumatology, Faculty of Medicine, The Chinese Bo Gao, Liu Yang, Zhuo-Jing Luo University of Hong Kong, Hong Kong, China Xijing Hospital b Department of Chemical Pathology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China 252 c Spine Surgery, Drum Tower Hospital, Nanjing University Medical School, Nanjing, High speed vertebral kinematics in a rodent dislocation spinal cord injury model China Stephen Mattucci, Jie Liu, Paul Fijal, Wolfram Tetzlaff, Thomas Oxland d Joint Scoliosis Research Center, The Chinese University of Hong Kong and Nanjing University, Hong Kong, China University of British Columbia, ICORD 271 254 Effect of LIPUS on rabbit boneetendon junction healing at different initiating Trends toward using smart phone as a musculoskeletal assessment tool times: A confocal Raman microspectroscopy study Aliaa Rehan Youssef, Mohammed Gumaa Bakry Zhanwen Wanga, b, Can Chena, Hui Xieb, Hongbin Lua Cairo University a Department of Sports Medicine and Research Center of Sports Medicine, Xiangya Hospital of Central South University, Changsha, China 255 b Movement System Injury and Repair Research Center, Xiangya Hospital of Central Effect of electromagnetic therapy on mechanoreceptor number as a risk factor South University, Changsha, China of low back pain Mahmoud Nabhana, Haitham Sharaf El-Dinb 275 a Faculty Of Physical Therapy, Cairo University Endoplasmic reticulum stress-induced apoptosis contributes to articular cartilage degeneration via C/EBP homologous protein b Faculty of Science, Cairo University Yusuke Uehara 256 Department of Orthopaedic Surgery, Faculty of Life Sciences, Kumamoto University Role of muscle damage on loading at the level adjacent to a lumbar spine fusiondA biomechanical analysis 276 Masoud Malakoutiana, John Streetb, Hans-Joachim Wilkec, Ian Stavnessd, Marcel Icariin protects against bone loss in the hind limb suspension model b e a, b Dvorak , Sidney Fels , Thomas Oxland Xiu Fenga, b, Jinpeng Hea, Wengui Shia, c,HeLia, c, Junrui Huaa, Wenjun Weia, c, a, c a a a Department of Mechanical Engineering, University of British Columbia, Vancouver Sulan Lin , Nan Ding , Jufang Wang BC, Canada a Gansu Key Laboratory of Space Radiobiology, Institute of Modern Physics, Chinese b Department of Orthopaedics, University of British Columbia, Vancouver BC, Canada Academy of Sciences b c Institute of Orthopaedic Research and Biomechanics, Center of Musculoskeletal School of Pharmacy, Lanzhou University Research, University of Ulm, Ulm, Germany c University of Chinese Academy of Sciences Titles of other abstracts 147

277 293 Estrogen inhibits pre-osteoclasts proliferation and differentiation by upregu- A novel FGFR1-binding peptide attenuates the degeneration of articular lation of microRNA-210 through PI3K/AKT signaling pathway cartilage in adult mice Lei Guo, Lianfu Deng Qiaoyan Tan, Min Jin, Lin Chen Shanghai Ruijin Hospital, Shanghai Jiaotong University School of Medicine Daping Hospital, Third Military Medical University

294 280 Differentiation therapy of neoplastic stromal cells in giant cell tumor of bone Simulated microgravity alters cytoskeleton and ATP-binding related genes using the U.S. Food and Drug Administration (FDA)-approved drugs rapamycin expression in MLO-Y4 osteocytes and simvastatin Zhihao Chen, Fan Zhao, Yiduo Qi, Dijie Li, Peihong Su, Lifang Hu, Peng Shang, Carol P.Y. Laua, b, Stephen K.W. Tsuib, Shekhar M. Kumtaa Airong Qian a Department of Orthopaedics and Traumatology, Faculty of Medicine, The Chinese Key Laboratory for Space Biosciences & Biotechnology, Institute of Special University of Hong Kong Environmental Biophysics, School of Life Sciences, Northwestern Polytechnical b University, Xi’an, China School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong

282 295 Inhibition of natural antisense transcripts increases Macf1 expression and af- The effect of vitamin D supplement on muscle strength and physical fects cell migration in vitro performance in knee osteoarthritis patients Dijie Li, Chaofei Yang, Zhihao Chen, Ru Zhang, Peng Shang, Airong Qian Pacharee Manoya, Pongsak Yuktanandanab, Aree Tanavaleeb, Wilai Anomasiric, b, c Key Laboratory for Space Biosciences & Biotechnology, Institute of Special Sittisak Honsawek Environmental Biophysics, School of Life Sciences, Northwestern Polytechnical a Program in Medical Sciences, Faculty of Medicine, Chulalongkorn University, University, Xi’an, China Bangkok, Thailand b Department of Orthopaedics, Faculty of Medicine, Chulalongkorn University, 283 Bangkok, Thailand Treatment of chronic osteomyelitis c Department of Biochemistry, Faculty of Medicine, Chulalongkorn University, Yunfei Ma Bangkok, Thailand Nanfang Hospital, Southern Medical University, Guangzhou 307 Egr-1 regulated chondrogenesis via autophagy signal pathway 284 Ke Lua, Tian-Shu Shia, Wan-Li Lua, Bin Xueb, Qing Jianga Icariin regulates the balance between osteoblast and osteoclast differentiation a Drum Tower Hospital, School of Medicine, Nanjing University Dawei Zhanga, b, Li Liua, b, Jiantao Lina, b, Liao Cuia, b b State Key Laboratory of Pharmaceutical Biotechnology and Jiangsu Key a Guangdong Key Laboratory for Research and Development of Natural Drugs, Laboratory of Molecular Medicine, Model Animal Research Center and School of Guangdong Medical University, Zhanjiang, China Medicine, Nanjing University, Nanjing 210093, China b School of Pharmacy, Guangdong Medical University, Dongguan, China 309

285 Preparation of partially degradable PMMA-magnesium composite bone cements a a a, b a, b Knockdown of MACF1 inhibits osteoblastic cell proliferation Qingpan Zhai , Caihong Zhu , Huilin Yang , Bin Li a Peihong Su, Lifang Hu, Runzhi Li, Zhihao Chen, Peng Shang, Airong Qian Orthopedic Institute, Soochow University, Suzhou, China b Key Laboratory for Space Biosciences & Biotechnology, Institute of Special Department of Orthopaedic Surgery, The First Affiliated Hospital of Soochow Environmental Biophysics, School of Life Sciences, Northwestern Polytechnical University, Suzhou, China University, Xi’an, China 310 Cartilage extracellular matrix derived tissue engineering microtissue for 287 cartilage regeneration A novel CHST3 mutation in spondyloepiphyseal dysplasia with congenital joint Heyong Yin, Jiang Peng, Shibi Lu dislocations in a Chinese family Institute of Orthopedics, Chinese PLA General Hospital Wenjin Yan, Qing Jiang Department of Sports Medicine and Adult Reconstructive Surgery, Drum Tower 311 Hospital, School of Medicine, Nanjing University, Zhongshan Road 321, Nanjing Hydroxyapatite/silk fibroin composite microspheres loaded with methotrexate 210008, Jiangsu, China for repairing giant cell tumor-associated bone defects Qingpan Zhaia, Caihong Zhua, Zhangqin Yuana, Bin Lia, b 288 a Orthopedic Institute, Soochow University, Suzhou, China Silver ions doped calcium phosphate ceramic grafts are effective in the b treatment of chronic osteomyelitis: An experimental study in rabbits Department of Orthopaedic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, China Nusret Kosea, Mert Asfuroglu a, Mevlu¨tGu¨rbu¨zc, Ays‚egu¨l Akyu¨reklib, Varol S‚ahintu¨rka, Abdurrahman Kiremitcia, Aydın Dogan b 312 a Eskis‚ehir Osmangazi University, Medical Faculty Inhibitory effect of cycloastragenol on cellular damage caused by oxidative stress in MC3T3-E1 cells b Eskisehir Anadolu University, Material Engineering Jin Lia, b, Jingkai Wua, b, Yongjie Yua, b, Yajun Yanga, b, Weimin Yaoc, Yuyu Liua, b c Samsun University, Material Engineering a Department of Pharmacology, Guangdong Medical University, Zhanjiang, 289 Guangdong 524023, China b Enhanced chondrogenic differentiation of bone marrow-derived mesenchymal Guangdong Key Laboratory for Research and Development of Natural Drugs, stem cells in concave microwells with PDMS Guangdong Medical University, Zhanjiang, Guangdong 524023, China c Ji-Yun Ko, Ji-Min Lee, Gun-Il Im Affiliated Hospital of Guangdong Medical University Zhanjiang, Guangdong 524023, China Dongguk University Ilsan Hospital 313 290 Calcium phosphate cements reinforced with modified silk fibroin Maintaining induced pluripotent stem cells through culture on nanopattern Muli Hua, Caihong Zhua, Huilin Yanga, b, Bin Lia, b polydimethylsiloxane membrane a Orthopedic Institute, Soochow University, Suzhou, China Ji-Yun Ko, Ji-Min Lee, Gun-Il Im b Department of Orthopaedic Surgery, The First Affiliated Hospital of Soochow Dongguk University Ilsan Hospital University, Suzhou, China 148 Titles of other abstracts

314 326 Osteogenic effect of silicon-doped titanium dioxide nanotubes on titanium Autophagy delays cisplatin-induced apoptosis in human osteosarcoma cell line surfaces MG63 Tao Wanga, b, Xijiang Zhaob, c, Junying Sunb, Shi Qind, Xuanyong Liud, Bin Lia, b Zhicai Zhang a Orthopedic Institute, Soochow University, Suzhou, China Union Hospital, Tongji Medical College, Huazhong University of Science and b Department of Orthopaedic Surgery, The First Affiliated Hospital of Soochow Technology University, Suzhou, China 328 c Department of Orthopedic Surgery, The Affiliated Hospital of Jiangnan University, Palliative operation for the treatment of painful upper cervical spine Wuxi, China metastasis: Case series and review of the literature d State Key Laboratory of High performance Ceramics and Superfine Microstruc- Xinghuo Wu tures, Chinese Academy of Sciences, Shanghai, China Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 316 Functional identification and characterization of microRNAs for senile 329 osteoporosis Anticancer effect of (s)-crizotinib on osteosarcoma cells by targeting MTH1 Fan Zhaoa, Jianhua Maa, Wuxia Qiua, Pai Wanga, Zhihao Chena, Lifang Hua, Peng Xiangcheng Qing a b a Shang , Tuanmin Yang , Airong Qian Union Hospital, Tongji Medical College, Huazhong University of Science and a Key Laboratory for Space Biosciences & Biotechnology, Institute of Special Technology Environmental Biophysics, Northwestern Polytechnical University School of Life Sciences, Xi’an, China 331 b Department of Bone Disease Oncology, Hong-Hui Hospital, Xi’an Jiaotong Uni- RIPK1/RIPK3-mediated necroptosis contributes to compression-induced rat versity College of Medicine, Xi’an, China nucleus pulposus cell death Songfeng Chen 319 Union Hospital, Tongji Medical College, Huazhong University of Science and The phenotype and extracellular matrix production of chondrocytes Technology transfected by Ras-shRNA and Sox9 in 3D dynamic culture system 332 Xincheng Liu, Yushen Zhang, Yingsen Xue, Hongbin Fan Efficacy analysis of zoledronic acid combined with PKP in the treatment of Department of Orthopedic Surgery, Xijing Hospital, the Fourth Military Medical osteoporotic vertebral compression fractures as well as the restoration of University, Xi’an, China vertebral height loss Bingchen Shan, Xiaozhong Zhou 320 Department of Orthopaedics, the Second Affiliated Hospital, Soochow University The synergistic anticancer effect of cisplatin combined with Oldenlandia diffusa in osteosarcoma MG-63 cell line in vitro 333 Feifei Pu Human intra-articular stem cells isolated during arthroscopic surgery as a new cell source with high potential for cartilage regeneration Union Hospital, Tongji Medical College, Huazhong University of Science and a a a b a a Technology Jun Li , Yuhong Liang , Zhiyu Zhou , Weimin Zhu , Wenjin Peng , Quangqian Zhou a The Centre for Anti-ageing and Regenerative Medicine, Shenzhen University, 321 Shenzhen, China b Effect of microRNA-101 on proliferation and apoptosis of human osteosarcoma The First Affiliated Hospital of Shenzhen University, Shenzhen, China cells by targeting mTOR 334 Zengwu Shao The risk of femoral head collapse following hip fixation is influenced by head Union Hospital, Tongji Medical College, Huazhong University of Science and size and AVN lesion size but not implant type Technology Alisdair MacLeod, H.S. Gill, Elise Pegg

322 The University of Bath Association between GSTP1 polymorphisms and prognosis of osteosarcoma 337 patients treated with chemotherapy: A meta-analysis Differential intensity-dependent effects of pulsed electromagnetic fields on Feifei Pu RANKL-induced osteoclast formation, cytoskeletal organization and bone resorption in RAW 264.7 cells Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Pan Wang, Juan Liu, Yuefan Yang, Lu Cao, Mingming Zhai, Erping Luo, Jing Da Fourth Military Medical University 323 338 Co-culture of primary chondrocytes and umbilical cord Wharton’s jelly-derived mesenchymal stem cells in 3D enhances the expression of cartilaginous Gene expression profiling shows the dysregulation of multiple hormone extracellular matrix components signaling in osteoporosis that could be therapeutically reversed by treatment with strontium gluconate Yu Zhang Jun Li, Yuhong Liang, Wenjin Peng, Tuanhui Chen, Meiling Zhou, Guangqian Zhou Chinese PLA General Hospital The Centre for Anti-ageing and Regenerative Medicine, Shenzhen University, Shenzhen, China 324 siRNA-mediated HIF-1a gene silencing affects angiogenesis in osteosarcoma 341 Qiang Wu Evaluation of the osteogenesis and angiogenesis effects of porous n-HA/collagen Union Hospital, Tongji Medical College, Huazhong University of Science and doped lithium scaffold combined with gelatin microspheres/rhEPO: An in vitro Technology study Donghai Li, Pengde Kang, Zhouyuan Yang, Xiaowei Xie, Jinhai Zhao, Haiyan Zhao 325 West China Hospital, Sichuan University The role of c-Kit-Gai/Gab1 signaling pathway in bone marrow mesenchymal stem cell proliferation 342 Shiji Fanga, b, Songtao Lia, b, Zhentao Zhoua, Cong Caob, Xiaozhong Zhoua A novel ultrasound microbubble contrast agent: Application for ultrasound a The Department of Orthopedics, the Second Affiliated Hospital of Soochow image enhancement and therapy for arteriovenous thrombosis University, Suzhou 215000, China Bingyang Dai, Lan Li, Qing Jiang b Neurosience Institute of Soochow University, Suzhou, Jiangsu 215000, China Drum Tower Hospital, School of Medicine, Nanjing University Titles of other abstracts 149

343 362 mTORC1 regulates PTHrP to coordinate chondrocyte growth, proliferation and Furin mediated Ac45 maturation is important for osteoclast bone resorption differentiation. An Qin, Tingting Tang, Jiake Xu Bo Yan, Dadi Jin, Xiaochun Bai Shanghai Jiao Tong University The Third Affiliated Hospital of Southern Medical University 365 344 Effects of facet joints and intervertebral disc on degenerative lumbar and A novel osteoblast differentiation inhibiting lncRNA, AK138929 lumbosacral spondylolisthesis: An in vitro biomechanical investigation Chong Yina, Yan Zhanga, Kun Yana, Zhihao Chena, Dijie Lia, Fan Zhaoa, Lifang Hua, Qingan Zhu, Ruozhou Zhou, Zhiping Huang, Xiang Liu, Jianting Chen b c a a Yonghua Wang , Ge Zhang , Peng Shang , Airong Qian Nanfang Hospital, Southern Medical University a Northwestern Polytechnical University 366 b School of Life Sciences, Northwest A&F University Efficacy of a clinical research course for surgeons in low-resource settings c School of Chinese Medicine, Hong Kong Baptist University Theodore A. Miclaua, Kathryn Chomsky-Higginsb, Saam Morshedb, Mohit Bhandaric, d e e b 350 Fernando de la Huerta , Alfredo Ceballos , Roberto Balmaseda , Theodore Miclau a Bacteriophage therapy in periprosthetic infections: An experimental study Stanford University b Cengiz Yilmaza, Mehmet Colaka, Banu Coskun Yilmaza, Gulden Ersoza, University of California, San Francisco Mzia Kutateladzeb, Mehmet Gozlugolc c McMaster University a University of Mersin, Turkey d Instituto Mexicano del Seguro Social b Eliava Institute, Georgia e Centro de Investigaciones Medico-Quiruricas c Turkey Ministry of Health 368 351 Cyclic tensile stretch induces apoptosis in human cartilage endplate-derived stem cells Abnormal functions of osteocyte-lacuno-canalicular system in adolescent idiopathic scoliosis Chao Yuan, LuQiao Pu, Jian Wang Wayne Y.W. Leea, Huan-xiong Chena, Jia-jun Zhanga, Zhi-wei Wanga, Bobby K.W. Department of Orthopaedics, XinQiao Hospital, The Third Military Medical Nga, Kwong Man Leea, Tsz-ping Lama, Jian Q. Fengb, Jack C.Y. Chenga University a Department of Orthopaedics & Traumatology, The Chinese University of Hong 369 Kong, Hong Kong, China Transcription factor, TIEG1 is a key molecule in TGF-b mediated hypertrophy b Department of Biomedical Sciences, Texas A&M University Baylor College of signal mechanism during chondrogenesis of MSCs Dentistry, Dallas, Texas, USA Jong-Min Leeb, Hye-Young Kima, Gun-Il Ima 352 a Department of Orthopaedics, Dongguk University Ilsan Hospital Bioadaptive nanorod topography of titanium surface to control cell behaviors b College of Medicine, Dongguk University and osteogenic differentiation of preosteoblast cells Shao Xua, Zhiyu Zhoub, Manman Gaob, Changye Zoub, Yinglin Cheb, Xuenong Zoub, 370 Lei Zhoua Insulin or IGF-1 enhances cartilaginous callus formation during diabetic bone a The Third Affiliated Hospital of Southern Medical University repair through distinct regulation of Glut1 expression a, b a, c d a, b a, b b Guangdong Provincial Key Laboratory of Orthopedics and Traumatology/Ortho- Fengjie Zhang , Li Yang , Qiling He , Wingpui Tsang , Chao Wan pedic Research Institute, The First Affiliated Hospital of Sun Yat-sen University, a Ministry of Education Key Laboratory of Regenerative Medicine, School of Guangzhou, China Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China 353 b School of Biomedical Sciences Core Laboratory, Institute of Stem Cell, Genomics Enhanced mechanical stability of osteochondral scaffold for large osteochon- and Translational Research, Shenzhen Research Institute, The Chinese University dral defect repair of Hong Kong, Shenzhen 518057, China Chaozong Liu c Department of Endocrinology, Southern Medical University Affiliated Zhujiang University College London Hospital, Guangzhou 510000, China d Department of Microbiology, University of Alabama at Birmingham, AL 35294, USA 354 371 Understanding structural changes in osteoarthritic subchondral bone Stand up and sit down assistance provided by CUHK-EXO exoskeleton Chaozong Liu Bing Chena, b, Chun Haob, Xuan Zhaob, Lai Yin Qinc, Kai Ming Chana, Sheung Wai University College London Lawa, Ling Qina, Wei Hsin Liaob a 355 Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong, China Silencing of carboxypeptidase E inhibits cell proliferation, tumorigenicity, and b metastasis of osteosarcoma cells Department of Mechanical and Automation Engineering, The Chinese University of Hong Kong, Hong Kong, China Shuli Fan c Division of Biomedical Engineering, The Chinese University of Hong Kong, Hong Department of Geriatrics, The First Affiliated Hospital of China Medical Kong, China University 372 357 Bisphosphonates in treatment of bone loss and fractures following Microbial attack: Organism identification and the host response hematopoietic stem cell transplantation: A systematic review and meta-analysis Yutaka Inaba, Hyonmin Choe, Naomi Kobayashi, Tomoyuki Saito Huifang Linda Lu, Xerxes Pundole, Hira Cheema, Gabriela Sanchez Petitto, Maria Yokohama City University Lopez-Olivo, Maria Suarez-Almazor University of Texas MD Anderson Cancer Center, Houston, Texas 360 Novel ACAN mutation causing dominant familial osteochondritis dissecans in a 373 Chinese family Protective effect of neuropeptide substance P on bone marrow mesenchymal Wenjin Yan, Qing Jiang stem cells against apoptosis induced by serum deprivation Department of Sports Medicine and Adult Reconstructive Surgery, Drum Tower Dan Jin, Su Fu, Song Liu Hospital, School of Medicine, Nanjing University, Nanjing, Jiangsu, China Nanfang Hospital, Southern Medical University 150 Titles of other abstracts

374 Yusuke Shiotab, d, Akira Taniguchia, Kstsuya Itob, Hiroaki Kurokawaa, Kiyonori a a c c Ⅱ Tomiwa , Tsukasa Kumai , Laohapoonrungsee Anupong , Mahakkanukrauh Pasuk , Clinical effects of locking compression plate for Neer b fractures of the distal a clavicle Yasuhito Tanaka a Dan Jin, Zhen-lv Zou, Su Fu Department of Orthopaedic Surgery, Nara Medical University b Nanfang Hospital, Southern Medical University Department of Orthopaedic Surgery, Yao General Hospital c Chiang Mai University 375 d Yoshimoto Orthopedics Hospital Comparative biomechanical evaluation of fixation methods in ior pilon fractures: A finite element analysis 387 Dan Jin, Su Fu, Song Liu Substance P and vascular endothelial growth factor expression of bone marrow Nanfang Hospital, Southern Medical University stromal cells and Wnt/b-catenin signaling pathway Dan Jin, Shang-chong Wang, Jun Liu 376 Nanfang Hospital, Southern Medical University Comparative finite element analysis of fixations in ior malleolar fracture Dan Jin, Su Fu, Jianqun Wu 388 Nanfang Hospital, Southern Medical University Substance P promotes BMSCs’ expression of BMP-2 and Wnt pathways mechanism research 377 Dan Jin, Jun Liu, Shangchong Wang Repair of goat bone defects by using porous antigen-free bovine cancellous bone Nanfang Hospital, Southern Medical University scaffold loaded with rhEPO and autologous bone marrow mononuclear cells 389 Jinhai Zhaoa, Pengde Kanga, Liqing Dengb, Donghai Lia, Xiaowei Xiea, Zhouyuan Yanga In vitro release of osteopromotive molecule puerarin from porous composite scaffolds for bone defect repair a WestChina Hospital Ling Lia, Long Lia, Shan Zhonga, Yuxiao Laia, Ling Qina, b, Xinluan Wanga, b, c b Hospital of Chengdu Office of People’s Government of Tibetan Autonomous Region a Translational Medicine R&D Center, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences 378 b Department of Orthopedics and Traumatology, the Chinese University of Hong Kong Comparison between staged ORIF and EFLIF in treatment of pilon fracture: A c Shanghai Key Laboratory of Orthopaedic Implants systematic review Dan Jin, Shijuan Xie 390 Nanfang Hospital, Southern Medical University The construction and stability affecting factors analysis of finite element models of ior malleolar fracture and ior pilon fracture 379 Dan Jin, Su Fu, Shenghui Ma Comparison on image morphology of ior pilon fracture fragment and ior ankle Nanfang Hospital, Southern Medical University fracture fragments Dan Jin, Shijuan Xie, Su Fu 393 Nanfang Hospital, Southern Medical University Overexpression of miR-503 promotes bone formation in distraction osteogenesis through suppressing Smurf1 380 Yuxin Suna, b, c, Jia Xue, Liangliang Xua, b, Jingfang Zhanga, b, Kai-ming Chana, b, d, c a, b, c Literature review of isolated talonavicular arthrodesis and a finite element Xiaohua Pan , Gang Li analysis for optimal screw placement a Department of Orthopaedics & Traumatology, Li Ka Shing Institute of Health Dan Jin, Shenghui Ma, Su Fu Sciences and Lui Che Woo Institute of Innovative Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong Nanfang Hospital, Southern Medical University SAR, PR China. 381 b The CUHK-ACC Space Medicine Centre on Health Maintenance of Musculoskeletal System, The Chinese University of Hong Kong Shenzhen Research Institute, Identification of IL-7 as a candidate disease mediator in osteoarthritis in Shenzhen, PR China. Chinese Han population: A case-control study c Department of Orthopaedics and Traumatology, Bao-An District People’s Hong-xin Zhanga, Yan-gui Wangb, Shun-yuan Lua, Xiong-xiong Lua, Jie Liua Hospital, Shenzhen, PR China. a Ruijin Hospital d Key Laboratory for Regenerative Medicine, Ministry of Education, School of b Yantaishan Hospital Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, PR China. 382 e Department of Orthopaedics and Traumatology, Shanghai Sixth People’s Hospital. Neuropeptide Y stimulates osteoblastic differentiation and VEGF expression of bone marrow stem cells in vitro 394 Dan Jin, Song Liu, Su Fu Icariin protects against cyclophosphamide-induced obstacle of mouse bone Nanfang Hospital, Southern Medical University marrow mesenchymal stem cells differentiating into osteoblasts Zhilie Yang a, b, Chenglong Wang a, b, Dongfeng Zhaoa, b, Junli Chang a, b, Yongjun 383 Wanga, b, Yanping Yanga, b Neuropeptide Y promotes proliferation and inhibits apoptosis of rat bone a Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, marrow mesenchymal stem cells in vitro partially by activating canonical Wnt 200032, China pathway b Institute of Spine, Shanghai University of Traditional Chinese Medicine, Shanghai, Dan Jin, Jianqun Wu, Song Liu 200032, China Nanfang Hospital, Southern Medical University 396 384 Molecular mechanism of the inhibitory effects of cyclophosphamide (CPD)- Safe zone of ior screw insertion for talar neck fractures induced bone loss in vivo and Receptor Activator for Nuclear Factor-kB Ligand (RANKL)-mediated osteoclastogeneisis in vitro Dan Jin, Shenghui Ma, Song Liu Dongfeng Zhaoa, b, Chenglong Wanga, b, Yanping Yanga, b, Yongjun Wanga, b Nanfang Hospital, Southern Medical University a Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 386 200032, China What is the most important factor for the stability of the distal tibiofibular b Institute of Spine, Shanghai University of Traditional Chinese Medicine, Shanghai, joint? 200032, China Titles of other abstracts 151

397 417 Effects of siRNA-mediated Cdc2 silencing on MG63 cell proliferation and When to stop aspirin during spine surgery depends on patients’ cardiovascular apoptosis riskdA prospective, randomized, double-blind, placebo-controlled study Xiangyong Que En Xie Three Gorges University, Yichang 443002, P.R. China Hong-Hui Hospital

398 419 Clinical characteristics and treatment of extremity chronic osteomyelitis in Sirt1 regulates growth plate chondrocytes differentiation and proliferation via Southern China: A retrospective analysis of 394 consecutive patients autophagy Nan Jiang, Bin Yu Xiaomin Kang, Wei Yang, XinXin Jin, Zhengmin Ma, Zhuang Qian, Tianpin Xie, Shufang Wu Nanfang Hospital, Southern Medical University The First Affiliated Hospital of Xi’an Jiaotong University School of Medicine 399 421 Femoral version, neck-shaft angle, and acetabular anteversion in Chinese Han Morbidity and mortality of major adult spinal surgery: An ambispective cohort population: A retrospective analysis of 466 healthy adults analysis of 977 patients Nan Jiang, Bin Yu En Xie Nanfang Hospital, Southern Medical University Hong-Hui Hospital

400 422 Long term muscle atrophy using botulinum toxin in lapine modle causes lumbar The impact of Scheuermann’s disease in single-level ior lumbar interbody degeneration fusion patients: Efficacy, radiographic and clinical outcomes a b c c a Sang Kuy Han , Young Eun Kim ,Sang-RaeLee, Kyu-Tae Chang , Keyoung Jin Chun En Xie a Korea Institute of Industrial Technology Hong-Hui Hospital b Dankook University 425 c Korea Research Institute of Bioscience and Biotechnology Kinematic analysis of ankle eversion sprain in sports: Two cases during the FIFA 404 World Cup CX-5461 induces autophagy and inhibits tumor growth via mTOR-related Xi Li, Daniel Fong, Kai-Ming Chan signaling pathways in osteosarcoma Department of Orthopaedics and Traumatology, Faculty of Medicine, The Chinese Leiming Lia, Yan Lib, Jiansong Zhaob, Shuli Fana, Liguo Wanga,XuLia University of Hong Kong a The First Affiliated Hospital, China Medical University, Shenyang, China 426 b ShengJing Hospital, China Medical University, Shenyang, China Inflammatory blood laboratory levels as markers of degenerative lumbar scoliosis surgery infection: A systematic review and meta-analysis 408 En Xie Strontium loaded nanotubular structures inhibit osteoclastogenesis by repres- Hong-Hui Hospital sion of the NF-kB, PI3K/Akt and CN/NFAT pathways in vivo and vitro Baoguo Mia, Wei Xionga, Xiang Xiaob, Hanfeng Guana, Yong Lia, Hui Liaoa, Zhong 427 a b a Fang , Jijiang Fu , Feng Li An algorithmic approach for managing orthopaedic surgical wounds of cicatri- a Tongji Medical College, Huazhong University of Science and Technology, Wuhan, cial scoliosisdNew technologies Hubei, China En Xie b The Key State Laboratory Breeding Base of Refractories and Ceramics, School of Hong-Hui Hospital Materials and Metallurgy, Wuhan University of Science and Technology, Wuhan, 430081, China 428 High efficiency of irrigation and debridement for early postoperative spine 409 infection in ADLS The effect of cemented and uncemented implants on the measurement of En Xie proximal femur BMD Hong-Hui Hospital Yue Ding, Guangtao Fu, Changchuan Li, Chi Zhang, Shixun Li, Wei Liu 429 The Memorial Hospital of Sun Yat-sen University Risk factors associated with deep surgical site infections after primary adult 412 degenerative lumbar scoliosis: System analysis of 1727 ALDS The osteogenesis and angiogenesis study of bone marrow mesenchymal stem En Xie cells promoted by shock waves Hong-Hui Hospital Jinhong Yang, Gengyan Xing 430 The Beijing Armed Police General Hospital Clinician-friendly motion capture system for kinematic assessment in ACL- 415 deficient knees before and after reconstruction surgery during single-leg-hop Limethason relieves inflammation in murine model of chronic asthma without Ruen Shan Leow, Kam Ming Mok, Sai Chuen Fu, Xi Li, Patrick Shu Hang Yung, Kai causing bone loss Ming Chan Siyu Li, Haoyu Wang, Yue Yang, Peng Wang, Shuai Wang, Mengyao Ma, Peng Shang, Department of Orthopaedics and Traumatology, Faculty of Medicine, The Chinese Airong Qian University of Hong Kong Key Laboratory for Space Biosciences & Biotechnology, Institute of Special 431 Environmental Biophysics, School of Life Sciences, Northwestern Polytechnical The risk of sepsis after long ior instrumentation and fusion: The impact of a University, Xi’an, China clinical pathway in ADLS

416 En Xie Cross sectional evaluation of serum levels of bone turnover markers in patients Hong-Hui Hospital with osteoarthritis 432 Sicong Min, Wanli Lu, Qing Jiang Risk factors of gastrointestinal hemorrhage after long ior instrumentation and Drum Tower Hospital, School of Medicine, Nanjing University fusion in degenerative adult lumbar scoliosis 152 Titles of other abstracts

En Xie 445 Hong-Hui Hospital MLCK regulates axon growth via reorganization of the growth cone cytoskeleton 為華 王 433 , Saijilafu 蘇州大學骨科研究所 Deletion of Macf1 in osteogenesis cells inhibits bone formation in postnatal mice 446 Xiaoli Ma, Fan Zhao, Wuxia Qiu, Ru Zhang, Pai Wang, Lifang Hu, Tianyuan He, Peng Shang, Airong Qian In-hospital activity monitoring after total hip arthroplasty (THA): Reference data for individualized rehabilitation and discharge protocol Key Laboratory for Space Biosciences & Biotechnology, Institute of Special Environmental Biophysics, School of Life Sciences, Northwestern Polytechnical Irma Marie-Louise Reedera, b, Matthijs Lippertsc, Ide C. Heyligersa, Bernd Grimma University, Xi’an, China a AHORSE Research Foundation, Department of Orthopaedics, Zuyderland Medical Centre, The Netherlands 435 b Maastricht University, The Netherlands The expression of miR-140-3p/-5p in synovial fluid of knee osteoarthritis c Department of Physics, St. Anna Hospital, Geldrop, The Netherlands Chunming Yin, Xiaohua Pan, Juan Zhou, Shuyun Xiang, Qiaoxuan Lin, Xiuli Lin

BaoAn Hospital affiliated to Southern Medical University & ShenZhen 8th People’s 448 Hospital Different degradation modes of PLGA/TCP/Puerarin scaffolds with different 436 preparations a, b a a a a a, b Effects of tanshinol on glucocorticoid-induced osteoporosis in rats Xinluan Wang , Ling Li , Long Li , Huijuan Cao , Yuxiao Lai , Ling Qin Shiying Luoa, Jingfeng Chena, Zhiguo Zhongb, Xiaohua Lva, Yajun Yanga, Liao Cuia a Translational Medicine R&D Center, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences a Guangdong Medical University b Department of Orthopedics and Traumatology, the Chinese University of Hong b Affiliated Hospital of Guangdong Medical University Kong 437 449 Proteomic studies on synovial fluid in knee osteoarthritis Study on improving orthopedic nurses’ empathy with The Balint Group Xiaohua Pan, Juan Zhou, Shuyun Xiang, Qiaoxuan Lin, Xiuli Lin, Chunming Yin Lin Zhang Department of Orthopaedics and Traumatology, BaoAn Hospital affiliated to Southern Medical University The West China Hospital of Sichuan University

438 450 Application of Huaxi Emotional-distress Index (HEI) in spine surgery inpatients Evaluation of the results from different nursing models on the terrible triad of Pei-fang Li, Ning Ning, Jiali Chen elbow postoperative functional recovery West China Hospital, Sichuan University XiaoYan Liu The West China Hospital of Sichuan University 439 Application of electromagnetic navigation in distal locking of long diaphyseal 451 interlocking intramedullary nailing The application of quality control circle in orthopedic trauma venous thrombus Zhentao Zhou, Xiaozhong Zhou, Bingchen Shan, Haibin Zhou, Zhengfeng Lu, Qirong embolism prevention Dong Yangyang Yang Department of Orthopaedics, the Second Affiliated Hospital, Soochow University The West China Hospital of Sichuan University 440 453 The application of video education in bladder management after spinal cord injury Adiponectin D276G/T polymorphism is associated with the risk of anterior cruciate ligament ruptures Mingxin Gao, Fengxian Jiang, Xiaozhong Zhou Wanvisa Udomsinprasert, Pongsak Yuktanandana, Sittisak Honsawek Department of Orthopaedics, the Second Affiliated Hospital of Soochow University Department of Biochemistry, Faculty of Medicine, Chulalongkorn University 441 The study of 3D printer of the spine of scoliotic patients in spinal operation 454 En Xie Tanshinol prevents bone loss induced by glucocorticoid through stimulating bone formation in rats Hong-Hui Hospital Jingfeng Chena, b, Shiying Luob, Minqun Dua, b, Wenxiu Laia, b, Yanlong Lianga, b, a, b a b a, b 442 Shuhui Li , Yingnian Lv , Tie Wu , Liao Cui a The microRNA miR-146a regulate cartilage homeostasis by targeting tgif1, Guangdong Key Laboratory for R & D of Natural Drugs, Guangdong Medical CaMKIId and calcineurin B University b Xudong Zhanga, Jingyu Zhaoa, Chuandong Wanga, Jiajia Xua, Yiyun Genga, Liming Department of Pharmacology, Guangdong Medical University Daia, Yan Huanga, Kerong Daia, Xiaoling Zhanga, b 456 a Institute of Health Sciences, Shanghai Institutes for Biological Sciences (SIBS) e b Raman spectroscopy for early diagnosis of staphylococcal osteomyelitis An Department of Orthopedic Surgery, Xinhua Hospital, Shanghai JiaoTong University in vitro study School of Medicine (SJTUSM), Shanghai, China Ahmed Al Ghaithia, Mohammed Khalida, Sharanjit Thakralb, Atika Al Bimanib, 443 Tanujjal Borab, Joydeep Duttab a Cognition on enhanced recovery after surgery of surgical medical staff Oman Medical Specialty Board Xinyu Zhang, Ning Ning, Peifang Li, Jiali Chen, Jiancheng Zeng, Xingcui Pu b Sultan Qaboos University West China Hospital, Sichuan University 457

444 Comparative study of conventional and ultrasonically-assisted bone drilling to measure micro-traumatic insult to the bone using electron scanning Long telomere length in blood leukocytes of patients with anterior cruciate microscopy ligament injury Ahmed Al Ghaithia, Alama Kb, Mohammed Kindib Pakorn Daechavijit, Jutharat Siridonthanakasem, Punyanuch Wongsupha, Pongsak a Yuktanandana, Sittisak Honsawek Oman Medical Specialty Board b Faculty of Medicine, Chulalongkorn University Sultan Qaboos University Titles of other abstracts 153

458 b Joint Research Centre for Bone and Joint Disease, Model Animal Research The rosiglitazone-induced bone loss can be attenuated with zoledronic acid Center c Xin Huang, Shilong Huang, Fei Xu, Xuejun Zhang, Yonghui Dong, Hui Liao, Fengjin Department of Bone Tumor, Drum Tower Hospital Affiliated to Medical School of Guo, Anmin Chen Nanjing University

Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong 470 University of Science and Technology, Wuhan 430030, China The alteration and crosstalk of articular cartilage-subchondral bone unit in 459 different stages of osteoarthritis Effects of fenofibrate on bone disorders in mice with type 2 diabetes mellitus Xueling Yuan, Haoye Meng, Yongcheng Wang, Cheng Wang, Jiang Peng, Quanyi Guo, Aiyuan Wang, Shibi Lu Tian-Shu Shia,KeLua, Bin Xueb, Qing Jianga Chinese PLA General Hospital a Drum Tower Hospital, School of Medicine, Nanjing University b State Key Laboratory of Pharmaceutical Biotechnology and Jiangsu Key 472 Laboratory of Molecular Medicine, Model Animal Research Center and School Engineered scaffold-free tendon tissue produced by stepwise inductive of Medicine, Nanjing University, Nanjing 210093, China differentiation of mesenchymal stem cells 460 Zi Yina, b, Xiao Chena, Hongwei Ouyanga, Gang Lib Axial perspective to find the largest intraosseous space available for a Zhejiang University percutaneous screw fixation of fractures of the acetabular anterior column b The Chinese University Of Hong Kong Xiaoreng Feng Department of Orthopaedics and Traumatology, Nanfang Hospital, Southern 476 Medical University Clinical effects of combined treatment of diabetic foot Congcong Su, Xiaohua Pan, Keliang Deng, Juan Zhou, Qiaoxuan Lin, Lili He, 461 Xiuli Lin Definition of the safe zone for antegrade lag screw fixation of acetabular ior BaoAn Hospital affiliated to Southern Medical University & ShenZhen 8th People’s column fracture by 3D technology Hospital Bin Chen Southern Medical University 477 MiR-144 inhibits tumor growth and metastasis in osteosarcoma via targeting 462 ROCK1 Isolation and characterization of homoisoflavonoids from Dragon’s blood Xiaoling Zhanga, b, Jing Lia, Zhiguang Qiaoa, Jiajia Xua, Kerong Daia (Dracaena cochinchinensis) and their osteogenic activities in mouse a mesenchymal stem cells The Key Laboratory of Stem Cell Biology, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences & Shanghai Jiao a, b b a a Xing Xu , Jinbiao Xu , Min Jiang , Lianfu Deng Tong University School of Medicine, China, 200025. a Shanghai Institute of Traumatology and Orthopaedics b Department of Orthopedic Surgery, Xinhua Hospital, Shanghai JiaoTong University b Lishui Institute of Agricultural Sciences School of Medicine

463 479 Online compared to paper questionnaires for patient follow-up in arthroplasty: PTH 1-34 affects the migration and differentiation of young and ovarectomized Clinical validity, patient preference and health economics bone marrow derived rat stem cells Jeannot Mijnes, Ide C. Heyligers, Bernd Grimm Liza Clouard, Anita Sanghani-Kerai, Timothy Briggs, Gordon Blunn AHORSE Research Foundation, Department of Orthopaedics, Zuyderland Medical University College London Center, Heerlen, Netherlands

464 480 Biomimetic tendon matrix for the ligament-to-bone reconstruction of ACL Osteoporosis and ageing reduces the migration of stem cells but this is ameliorated by CXCR4 Xiao Chen, Huan-Huan Liu, Long Yang Anita Sanghani Keraia, Melanie Coathupa, Sorousheh Samizadeha, Priya Kaliab, Lucy Zhejiang University Di Silviob, Bernadine Idowub, Gordon Blunna a 466 University College London b Osteoporosis and ageing affects stem cell differentiation and migration King’s College

Anita Sanghani Kerai, Melanie Coathup, Liza Osagie, Sorousheh Samizadeh, Gordon 481 Blunn Bone microstructure and regional distribution of osteoblast and osteoclast University College London activity in the osteonecrotic femoral head 467 Cheng Wang, Haoye Meng, Xueling Yuan, Aiyuan Wang, Quanyi Guo, Jiang Peng, Shibi Lu Version correction compromises remaining bone quality after eccentric reaming in B2 glenoids Chinese PLA General Hospital Xiang Chen, Reddy Akhil, Andreas Kontaxis, Dan Choi, Timothy Wright, David Dines, 482 Russel Warren, Lawrence Gulotta Bilayered ECM/hydroxyapatite scaffold with low permeability for osteochondral Hospital for Special Surgery interface in situ regeneration 468 Haoye Meng, Yongcheng Wang, Jiang Peng, Quanyi Guo, Aiyuan Wang, Shibi Lu Parathyroid hormone 1-34 reduces dexamethasone induced terminal Chinese PLA General Hospital differentiation in human articular chondrocytes Je-Ken Chang 483 Taiwan ORS Anti-inflammatory effects of pulsed electromagnetic fields (PEMF) treatment in rat intervertebral disc degeneration model 469 Xinyan Tanga, Dezba Coughlina, Annie Ouyanga, Ellen Liebenberga, Stefan Dudlia, Detecting LKB1 mutations in the cartilage tumors Erik Waldorffb, Nianli Zhangb, James Ryabyb, Jeffrey Lotza Liang Qiaoa, b, Sheng Zhoua, b, Jin Daia, Wenjin Yana, Shoufeng Wangc, Huajian a Department of Orthopaedic Surgery, University of California San Francisco, San b a Teng , Qing Jiang Francisco, CA, United States a Department of Sports Medicine and Adult Reconstruction, Drum Tower Hospital b Department of Research and Clinical Affairs, Orthofix Inc., Lewisville, Texas, Affiliated to Medical School of Nanjing University United States 154 Titles of other abstracts

484 502 Osteoprotegerin is key for the formation of heterotopic ossification The effects of hip-joint angle position on quadriceps muscle torque in healthy Song Xuea, Roberto J. Fajardob, Kevin P. McHugha non-athletic subjects a b a University of Florida Valerie Sparkes , Bodor Bin Sheeha a b University of Texas Health Science Center San Antonio Arthritis Research UK Biomechanics and Bioengineering Centre, Cardiff University b School of Healthcare Sciences, Cardiff University 485 Can biofeedback increase immediate post-operative activity levels in hip 503 arthroplasty patients? A RCT pilot study using wearable sensors Bone tissue engineering and regenerative medicine 2.0dFrom “proof-of- Irma Marie-Louise Reedera, b, Matthijs Lippertsc, Ide C. Heyligersa, Bernd Grimma concept” to “proof-of-value” a AHORSE Research Foundation, Department of Orthopaedics, Zuyderland Medical Zhiyong Zhang Centre, The Netherlands Shanghai Jiao Tong University, School of Medicine b Maastricht University, The Netherlands 505 c Department of Physics, St. Anna Hospital, Geldrop, The Netherlands Biomimetically ornamented rapid prototyping fabrication of an apatiteLcolla- L L L 486 gen polycaprolactone composite construct with nano micro macro hierarchical structure for large bone defect treatment Biomechanical investigation of lumbar spinal segments response under ) physiological functions Jinbing Wang, Zhi-Yong Zhang Moustafa Mosbah Shanghai Ninth Hospital Faculty of Sciences and Technology 506 一例脛骨平臺骨折患者的護理 487 莉莉 何 Assessment of the correlation between serum and synovial fetuin-A levels and severity of osteoarthritis in a mouse model of osteoarthritis 深圳市寶安區人民醫院 Nuray Cana, Huseyin Ozkanb, Muhammed Hanifi Gemcib, Faruk Akyıldızb, Omer 509 Ersenb, Servet Tunayb Serum metal ions and pathological changes of Armd in metal-on-metal hip a Department of Orthopaedics and Traumatology, Sarikamis Military Hospital, resurfacing arthroplasties Turkey Nicholas Athanasou, George Grammatopoulos, Mitsuru Munemoto, Sakis Pollalis b Department of Orthopaedics and Traumatology, Gulhane Military Medical Academy, Turkey Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sci- ences, University of Oxford 488 510 Effect of stretching exercise onset time on healing of strain-induced muscle injury in rats Deletion of Opg leads to increased neovascularization and expression of inflammation cytokines in the lumbar intervertebral disc of mice Tasneem Mohammada, Nabila Hassanb Xiaofeng Lia, b, Chunchun Xuea, b, Yongjian Zhaoa, b, Shaodang Chenga, b, Dongfeng a Department of Orthopedics, Faculty of Physical Therapy, Cairo University Zhaoa, b, Qianqian Lianga, b, Lin Chena, b, Qiang Wanga, b, Sheng Lua, b, Qi Shia, b, b Department of Pathology, National Research Center Yongjun Wanga, b, Bing Shua, b a 490 Longhua Hospital, Shanghai University of T.C.M., Shanghai, China b Mechanobiological modulation of Ca2D excitation and oscillations in osteocytes Spine Research Institute, Shanghai University of T.C.M., Shanghai, China of intact mouse calvaria by focused acoustic radiation force 514 Yi-Xian Qin, Minyi Hu, Daniel Gibbons, Jian Jiao Occult acetabular fractures in the elderly: A report of 3 cases and review of the Stony Brook University literature

491 Sean Ho, Marcus Lee, Ernest Kwek Physioxia promotes the stable articular cartilage tissue phenotype in self- Tan Tock Seng Hospital, Singapore organized tissue 515 Devon Andersona, Brandon Markwaya, Kenneth Weekesa, Helen McCarthyb, Quantification of forces and strains in anterior cruciate ligament during golf Brian Johnstonea swing motion a Oregon Health & Science University, Portland, OR, USA Yoon Hyuk Kima, Tserenchimed Purevsurena, SuKyoung Leeb, Kyungsoo Kima b Cardiff University, School of Biosciences, Cardiff, Wales, UK a Kyung Hee University 493 b Yonsei University Correlation between functional recovery and cell morphology following 517 induced tibialis anterior muscle strain in Wister rats Acellular dermal matrix as scaffold for cartilage regeneration Tasneem Mohammad Hui Qi, Lei Sun, Yongsheng Jie, Lei Chen, Shaofeng Jin, Rui Zheng Department of Orthopedics, Faculty of Physical Therapy, Cairo University Beijing Jishuitan Hospital 501 518 The effect of K-Tape on vastus medialis oblique, vastus lateralis and rectus femoris muscle activity and the critical knee flexion angle at which dynamic Evaluation of the articular cartilage and subchondral bone change in a model of valgus occurs during a single-leg squat spontaneous osteoarthritis in female Hartley guinea pigs Valerie Sparkes Ying Wang, Kejian Shi, Chengai Wu Arthritis Research UK Biomechanics and Bioengineering Centre, Cardiff University Beijing Institute of Traumatology and Orthopaedics