Fitzpatrick's Color Atlas and Synopsis of Clinical Dermatology

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Fitzpatrick's Color Atlas and Synopsis of Clinical Dermatology FITZPATRICK’S COLOR ATLaS aND SYNOPSIS OF CLINICAL DERMATOLOGY SEVENTH EDITION NOTICE Medicine is an ever-changing science. As new research and clinical experience broaden our knowledge, changes in treatment and drug therapy are required. The authors and the publisher of this work have checked with sources be- lieved to be reliable in their efforts to provide information that is complete and generally in accord with the standards accepted at the time of publication. However, in view of the possibility of human error or changes in medical sci- ences, neither the authors nor the publisher nor any other party who has been involved in the preparation or publication of this work warrants that the infor- mation contained herein is in every respect accurate or complete, and they dis- claim all responsibility for any errors or omissions or for the results obtained from use of the information contained in this work. Readers are encouraged to confirm the information contained herein with other sources. For example and in particular, readers are advised to check the product information sheet included in the package of each drug they plan to administer to be certain that the information contained in this work is accurate and that changes have not been made in the recommended dose or in the contraindications for administration. This recommendation is of particular importance in connec- tion with new or infrequently used drugs. FITZPATRICK’S COLOR ATLaS aND SYNOPSIS OF CLINICAL DERMATOLOGY SEVENTH EDITION Klaus Wolff, MD, FRCP Professor and Chairman Emeritus Department of Dermatology Medical University of Vienna Chief Emeritus, Dermatology Service General Hospital of Vienna Vienna, Austria Richard Allen Johnson, MD Assistant Professor of Dermatology Harvard Medical School Dermatologist Massachusetts General Hospital Boston, Massachusetts Arturo P. Saavedra, MD, PhD, MBA Assistant Professor in Dermatology, Dermatopathology and Medicine Brigham and Women’s Hospital Harvard Medical School Boston, Massachusetts New York Chicago San Francisco Lisbon London Madrid Mexico City Milan New Delhi San Juan Seoul Singapore Sydney Toronto Copyright © 2013, 2009, 2005, 2001, 1997, 1993, 1983 by McGraw-Hill Education, LLC. All rights reserved. Except as permitted under the United States Copyright Act of 1976, no part of this publication may be reproduced or distributed in any form or by any means, or stored in a database or retrieval system, without the prior written permission of the publisher. ISBN: 978-0-07-179303-2 MHID: 0-07-179303-8 The material in this eBook also appears in the print version of this title: ISBN: 978-0-07-179302-5, MHID: 0-07-179302-X. All trademarks are trademarks of their respective owners. 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Contents Preface xxiii Acknowledgment xxv Introduction xxvii Approach to Dermatologic Diagnosis xxviii Outline of Dermatologic Diagnosis xxviii Special Clinical and Laboratory Aids to Dermatologic Diagnosis xxxvi PART I Disorders PresentinG in tHe Skin and MUcoUs Membranes SECTION 1 DISORdERS OF SEBACEOUS ANd APOCRINE GLANdS 2 Acne Vulgaris (Common Acne) and Cystic Acne 2 Rosacea 8 Perioral Dermatitis 12 Hidradenitis Suppurativa 14 Fox Fordyce Disease 17 SECTION 2 ECZEMA/DERMATITIS 18 Contact Dermatitis 18 Irritant Contact Dermatitis (ICD) 18 Acute Irritant Contact Dermatitis 19 Chronic Irritant Contact Dermatitis 21 Special Forms of ICD 23 Allergic Contact Dermatitis 24 Special Forms of ACD 28 Allergic Contact Dermatitis Due to Plants 28 Systemic Acd 30 Airborne ACD 30 Atopic Dermatitis 31 Suggested Algorithm of AD Management 39 Lichen Simplex Chronicus (LSC) 39 Prurigo Nodularis (PN) 41 Dyshidrotic Eczematous Dermatitis 42 Nummular Eczema 43 vii viii Contents Autosensitization Dermatitis 44 Seborrheic Dermatitis 45 Asteatotic Dermatitis 48 SECTION 3 PSORIASIS ANd PSORIASIFORM DERMATOSES 49 Psoriasis 49 Psoriasis Vulgaris 49 Pustular Psoriasis 56 Palmoplantar Pustulosis 56 Generalized Acute Pustular Psoriasis (Von Zumbusch) 57 Psoriatic Erythroderma 59 Psoriatic Arthritis 59 Management of Psoriasis 59 Pityriasis Rubra Pilaris (PRP) 62 Pityriasis Rosea 65 Parapsoriasis en Plaques (PP) 67 Pityriasis Lichenoides (Acute and Chronic) (PL) 70 SECTION 4 ICHTHYOSES 72 Dominant Ichthyosis Vulgaris (DIV) 72 X-Linked Ichthyosis (XLI) 75 Lamellar Ichthyosis (LI) 77 Epidermolytic Hyperkertosis (EH) 78 Ichthyosis in the Newborn 80 Collodion Baby 80 Harlequin Fetus 81 Syndromic Ichthyoses 82 Acquired Ichthyoses 84 Inherited Keratodermas of Palms and Soles 84 SECTION 5 MISCELLANEOUS EPIdERMAL DISORdERS 87 Acanthosis Nigricans (AN) 87 Darier Disease (DD) 89 Grover Disease (GD) 91 Hailey–Hailey Disease (Familial Benign Pemphigus) 92 Disseminated Superficial Actinic Porokeratosis (DSAP) 93 Contents ix SECTION 6 GENETIC ANd ACQUIREd BULLOUS DISEASES 94 Hereditary Epidermolysis Bullosa (EB) 94 Pemphigus 101 Bullous Pemphigoid (BP) 107 Cicatricial Pemphigoid 109 Pemphigoid Gestationis (PG) 110 Dermatitis Herpetiformis (DH) 111 Linear IgA Dermatosis (LAD) 113 Epidermolysis Bullosa Acquisita (EBA) 114 SECTION 7 NEUTROPhIL-MEdIATEd DISEASES 116 Pyoderma Gangrenosum (PG) 116 Sweet Syndrome (SS) 120 Granuloma Faciale (GF) 122 Erythema Nodosum (EN) Syndrome 122 Other Panniculitides 125 SECTION 8 SEVERE ANd LIFE-ThREATENINg SKIN ERUPTIONS IN ThE ACUTELy ILL PATIENT 127 Exfoliative Erythroderma Syndrome (EES) 127 Rashes in the Acutely Ill Febrile Patient 133 Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) 137 SECTION 9 BENIgN NEOPLASMS ANd HyPERPLASIAS 141 Disorders of Melanocytes 141 Acquired Nevomelanocytic Nevi (NMN) 141 Halo Nevomelanocytic Nevus 146 Blue Nevus 148 Nevus Spilus 149 Spitz Nevus 151 Mongolian Spot 152 Nevus of Ota 153 Vascular Tumors and Malformations 154 Vascular Tumors 155 Hemangioma of Infancy (HI) 155 Pyogenic Granuloma 159 x Contents Glomus Tumor 160 Angiosarcoma 161 Vascular Malformations 161 Capillary Malformations 162 Port-Wine Stain 162 Spider Angioma 164 Venous Lake 165 Cherry Angioma 166 Angiokeratoma 167 Lymphatic Malformation 169 “Lymphangioma” 169 Capillary/Venous Malformations (CVMs) 170 Miscellaneous Cysts and Pseudocysts 172 Epidermoid Cyst 172 Trichilemmal Cyst 173 Epidermal Inclusion Cyst 173 Milium 174 Digital Myxoid Cyst 175 Miscellaneous Benign Neoplasms and Hyperplasias 176 Seborrheic Keratosis 176 Becker Nevus (BN) 179 Trichoepithelioma 180 Syringoma 181 Sebaceous Hyperplasia 182 Nevus Sebaceous 182 Epidermal Nevus 183 Benign Dermal and Subcutaneous Neoplasms and Hyperplasias 184 Lipoma 184 Dermatofibroma 185 Hypertrophic Scars and Keloids 186 Infantile Digital Fibromatosis 189 Skin Tag 190 SECTION 10 PhOTOSENSITIVITy, PhOTO-INdUCEd DISORdERS, ANd DISORdERS By IONIZINg RAdIATION 191 A Skin Reactions to Sunlight 191 Acute Sun Damage (Sunburn) 193 Drug-/Chemical-Induced
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