Anti-PARD6A Monoclonal Antibody, Clone FQS23489 (DCABH-6710) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

Anti-PARD6A monoclonal antibody, clone FQS23489 (DCABH-6710) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Product Overview Rabbit monoclonal to PAR6 - N-terminal

Antigen Description Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in the formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6- PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.

Immunogen Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human PAR6 aa 1-100 (Cysteine residue). The exact sequence is proprietary.Database link: Q9NPB6

Isotype IgG

Source/Host Rabbit

Species Reactivity Mouse, Rat, Human

Clone FQS23489

Purity Tissue culture supernatant

Conjugate Unconjugated

Applications IP, WB

Positive Control HeLa, 293T, Jurkat, Y79 and fetal liver lysates.

Format Liquid

Size 100 μl

Preservative None

Storage Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle.

Ship Shipped at 4°C.

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Gene Name PARD6A par-6 partitioning defective 6 homolog alpha (C. elegans) [ Homo sapiens ]

Official Symbol PARD6A

Synonyms PARD6A; par-6 partitioning defective 6 homolog alpha (C. elegans); par 6 (partitioning defective 6, C.elegans) homolog alpha; partitioning defective 6 homolog alpha; PAR 6; PAR 6A; PAR6alpha; TAX40; TIP 40; PAR-6 alpha; Tax-interacting protein 40; tax int

Entrez Gene ID 50855

Protein Refseq NP_001032358

UniProt ID Q9NPB6

Chromosome Location 16q22.1-q22.3

Pathway CDC42 signaling events, organism-specific biosystem; Cell junction organization, organism- specific biosystem; Cell-Cell communication, organism-specific biosystem; Cell-cell junction organization, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Insulin Pathway, organism-specific biosystem;

Function GTP-dependent protein binding; Rho GTPase binding; protein binding; protein kinase C binding; transcription factor binding;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]