Oncomodulin-1 Recombinant Protein Cat. No.: 91-225

Oncomodulin-1 Recombinant Protein

Specifications

SPECIES: Human

SOURCE SPECIES: E. coli

SEQUENCE: Met1-Ser109

FUSION TAG: N-6 His tag

TESTED APPLICATIONS:

APPLICATIONS: This recombinant protein can be used for biological assays. For research use only.

PREDICTED MOLECULAR 14.3 kD WEIGHT:

Properties

Greater than 95% as determined by reducing SDS-PAGE. PURITY: Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

PHYSICAL STATE: Lyophilized

Lyophilized from a 0.2 um filtered solution of 50mM Tris, 100mM NaCl, pH 7.5. It is not BUFFER: recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

September 29, 2021 1 https://www.prosci-inc.com/oncomodulin-1-recombinant-protein-91-225.html Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks. STORAGE CONDITIONS: Reconstituted protein solution can be stored at 4-7˚C for 2-7 days. Aliquots of reconstituted samples are stable at -20˚C for 3 months.

Additional Info

OFFICIAL SYMBOL: OCM

ALTERNATE NAMES: Oncomodulin-1, OM, Beta, OCM, OCM1, OCMN

ACCESSION NO.: P0CE72

GENE ID: 654231

Background and References

Oncomodulin-1 (OM) is a small, calcium-binding protein and a -derived , which can promote regeneration in retinal ganglion cells. Oncomodulin-1 is constitutively secreted by activated in the vitreous and retina in response to inflammatory conditions that promote optic nerve regeneration. Oncomodulin-1 binds RGCs with high affinity in vitro, but only when cAMP is BACKGROUND: pharmacologically elevated or if the membrane is permeabilized allowing Oncomodulin-1 access to the cytosolic compartment. Oncomodulin-1 is a member of the superfamily of proteins and is a high-affinity calcium ion-binding protein and contains 2 EF- hand domains. OM is found in early embryonic cells in the placenta and also in tumors. It has some calmodulin-like activity with respect to enzyme activation and growth regulation.

ANTIBODIES FOR RESEARCH USE ONLY.

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September 29, 2021 2 https://www.prosci-inc.com/oncomodulin-1-recombinant-protein-91-225.html