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Revista Română De Cardiologie REVISTA ROMÂNĂ DE CARDIOLOGIE ROMANIAN HEART JOURNAL Vol. XXI, Nr. 2, 2006 REVISTA ROMÂNĂ DE CARDIOLOGIE REVISTA SOCIETĂŢII ROMÂNE DE CARDIOLOGIE COLECTIVUL DE REDACŢIE Redactor șef: Redactor șef adjunct: Prof. Dr. Eduard Apetrei Prof. Dr. Carmen Ginghină Redactori: Redactori asociaţi: Prof. Dr. Radu Căpâlneanu Dr. Mihaela Rugină Prof. Dr. Cezar Macarie Dr. Ruxandra Jurcuţ Dr. Bogdan A. Popescu Dr. Costel Matei Redactor fondator Prof. Dr. C. Carp Colegiul de redacţie: Prof. Dr. E. Grosu – R. Moldova Prof. Dr. Ion V. Bruckner – București Prof. Dr. Alexandru Ioan – București Prof. Dr. Alexandru Câmpeanu – București Prof. Dr. Dan Dominic lonescu – Craiova Prof. Dr. Mircea Cinteză – București Dr. Matei Iliescu – București Dr. Radu Ciudin – București Prof. Dr. Ioan Maniţiu – Sibiu Prof. Dr. Radu Cristodorescu – Timișoara Prof. Dr. Gerald A. Maurer – Austria Prof. Dr. D.V. Cokinos – Grecia Dr. Șerban Mihăileanu – Franţa Dr. Dan Deleanu – București Prof. Dr. Nour Olinic – Cluj Napoca Prof. Dr. Genevieve Derumeaux – Franţa Prof. Dr. Fausto Pinto – Portugalia Prof. Dr. Doina Dimulescu – București Prof. Dr. Mariana Rădoi – Brașov Prof. Dr. Maria Dorobanţu – București Prof. Dr. Willem J. Remme – Olanda Prof. Dr. Ștefan Iosif Drăgulescu – Timișoara Dr. Doina Rogozea – București Prof. Dr. Guy Fontaine – Franţa Prof. Dr. Michal Tendera – Polonia Prof. Dr. Bradu Fotiade – București Prof. Dr. Ion Ţintoiu – București Prof. Dr. Alan Fraser – Anglia Prof. Dr. Panagiotis Vardas – Grecia Prof. Dr. Mihai Gheorghiade – USA Conf. Dr. Dragoș Vinereanu – București Prof. Dr. George Georgescu – Iași Prof. Dr. Marius Vintilă – București Prof. Dr. Leonida Gherasim – București Prof. Dr. Dumitru Zdrenghea – Cluj Napoca Redactor de număr: Dr. Mihaela Rugină 84 CUPRINS VOL. XXI, nr. 2, 2006 ARTICOLE ORIGINALE ..................................................................................................................... 89 Studiul SEPHAR– Studiu de Prevalenþã a Hipertensiunii Arteriale ºi evaluare a riscului cardiovascular în România – Partea I-a – Metodologie- Maria Dorobanþu, Roxana Darabont, Elisabeta Bãdilã, Mihaela Luca, Georgeta Datcu, Rodica Avram, Mariana Rãdoi, Elvira Craiu, Rodica Muºetescu, Cãlin Pop, Minerva Muraru, Imre Benedek, Marilena Bãnicã, Ingrid Lambru ............................................................................................................ 89 Extrasistolele atriale pot fi revelatoare de infarct atrial?-Radu Grigore ........................................................... 96 Transpoziþie corectatã de mari vase – complicaþiile etapei adulte- M. Marin Þârlea, Coman I.M., Ghionea M., Pãun Adriana. ........................................................................................................................................................ 100 Infarct miocardic acut sau hemoragie cerebralã ?-Diana Zamfir, Gabriel Tatu-Chiþoiu, Cristina Teodorescu, Cristina Filip, Simona Vizeteu, Maria Dorobanþu .................................................................................................103 REFERATE GENERALE ................................................................................................................... 110 Hipertensiunea arterialã ºi stenoza aorticã degenerativã - relaþie de cauzalitate, consecinþe hemodinamice ºi perspective terapeutice-Gabriela Badea, E. Apetrei ............................................................................................ 110 Semnificaþia clinicã ºi epidemiologia insuficienþei cardiace diastolice-Daniela Toporan, Daniele Rovai........ 115 NOÞIUNI DE STATISTICÃ MEDICALÃ ......................................................................................... 127 Exprimarea riscului (II) – Cristian Bãicuº .......................................................................................................... 127 ACTUALITÃÞI ÎN CARDIOLOGIE ................................................................................................. 130 IMAGINI ÎN CARDIOLOGIE ............................................................................................................ 133 Angina stabilã de efort-evoluþie particularã-Mihaela Ruginã, Monica Bengus, Daniel Gherasim, M.Postu, Carmen Beladan, E. Apetrei .......................................................................................................................... e1.... 133 ECHO QUIZ– Aura Popa, Marinela ªerban, Mihaela Florescu ................................................................. e2.. 136 GHID DE DIAGNOSTIC ªI TRATAMENT AL BOLILOR PERICARDULUI-Grupul de lucru în diagnostic- ul ºi tratamentul afecþiunilor pericardului al Societãþii Europene de Cardiologie-2004 ......................... ....... 137 INSTRUCÞIUNI PENTRU AUTORI ................................................................................................. 169 Figurile de pe coperta 1 : Fig. 1.ECG înregistrat în timpul testului ECG de efort. La 3 minunte apare subdenivelare ST 0.4-0.8 mm DII, DIII, aVF, V5, V6 ºi supradenivelare ST de 0.4 mm aVL (pag. 133) Fig.2. Coronarografie-Leziune unicoronarianã- Stenozã 90% artera descendentã anterioarã, segmentul II (pag.134) e1, e2- aceste articole vor putea fi accesate pe www.cardioportal.ro 85 Rãspunderea pentru conþinutul articolelor publicate revine în întregime autorilor. Opiniile, ideile, rezultatele studiilor publicate în Revista Românã de Cardiologie sunt cele ale autorilor ºi nu reflectã poziþia ºi politica Societãþii Române de Cardiologie. Nici o parte a acestei publicaþii nu poate fi reprodusã, stocatã, transmisã sub nici o formã sau mijloc (electronic, mecanic, fotocopie, înregistrare) fãrã permisiunea scrisã a editorului. © Toate drepturile rezervate Societãþii Române de Cardiologie. 86 Din numãrul urmãtor: • Strategii de tratament în ºocul cardiogen din infarctul miocardic acut cu supradenive- lare de ST • Angina Prinzmetal • Rezultatele studiului SEPHAR 87 ARTICOLE ORIGINALE STUDIUL SEPHAR– STUDIU DE PREVALENŢĂ A HIPERTENSIUNII ARTERIALE ȘI EVALUARE A RISCULUI CARDIOVASCULAR ÎN ROMÂNIA PARTEA I-A - METODOLOGIE Maria Dorobanţu1, Roxana Darabont2, Elisabeta Bădilă1, Mihaela Luca3, Georgeta Datcu4, Rodica Avram5, Mariana Rădoi6, Elvira Craiu7, Rodica Mușetescu8, Călin Pop9, Minerva Muraru10, Imre Benedek11, Marilena Bănică12, Ingrid Lanbru13 1Spitalul Clinic de Urgenţă București; 2Spitalul Universitar București; 3Bios Diagnostic; 4Spitalul „Sf. Spiridon” Iași; 5Spitalul Judeţean Timișoara; 6Spitalul Judeţean Brașov; 7Spitalul Judeţean Constanţa; 8Centrul de Cardiologie Craiova; 9Spitalul Judeţean Baia Mare; 10Spitalul Clinic Coltea București; 11Spitalul Judeţean Târgu Mureș; 12Servier Pharma; 13Compania Mercury Research Rezumat Hipertensiunea arterialã reprezintã unul dintre factorii majori de risc cardiovascular care poate fi influenþat prin mijloace terapeutice. Cu toate acestea, hipertensiunea rãmâne încã o problemã majorã de sãnãtate în întreaga lume datoritã con- trolului complet nesatisfãcãtor ºi asocierii frecvente cu alþi factori de risc cardiovasculari. Absenþa unor date generale de prevalenþã a hipertensiunii ºi a altor factori de risc cardiovascular în România, a determinat iniþierea în 2005, la iniþiativa Grupului de Lucru de Hipertensiune Arterialã, a unui studiu naþional (SEPHAR) care a urmãrit obþinerea acestor parametri. În studiu am folosit metoda eºantionãrii stratificate. Pentru a avea semnificaþie statisticã, în raport cu întreaga populaþie a þãrii, dimensiunile eºantionului au fost proiectate pentru minim 2000 cazuri finalizate. Suprafaþa României a fost împãrþitã în ºapte regiuni plus Bucureºtiul - recomandate de Comisia Naþionalã de Statisticã. La final, studiul a inclus 2107 subiecþi. S-a considerat drept caz finalizat subiectul care a acceptat sã participe la studiu, care a rãspuns la ches- tionar ºi cãruia i s-au recoltat probele de sânge conform protocolului. Studiul SEPHAR este astfel primul studiu epidemiologic din România care s-a bazat pe o eºantionare reprezentativã pen- tru întreaga populaþie a þãrii. Este primul studiu care a evaluat concomitent hipertensiunea arterialã ºi distribuþia în pop- ulaþie a celorlalþi factori de risc cardiovascular. Abstract Arterial hypertension is one of the major cardiovascular risk factors which could be modified by therapeutic methods. However, hypertension is still a major health problem all over the world because its control is completely unsatisfacto- ry and its frequent association with other cardiovascular risk factors. The absence of general data about the prevalence of arterial hypertension and other cardiovascular risk factors in Romania, was the reason for starting in 2005 a national study (SEPHAR), initiated by Hypertension Working Group, whose main goal was to assess these parameters. In the study, we used the method of stratified proportional sampling. In order to have a statistical significance in relation to the whole population of the country, the dimensions of the sample were designed for a minimum of 2000 finalized cases. Romania’s area was divided into seven regions plus Bucharest – recommended by The National Commission of Statistics. At the end, the study included 2017 subjects. A case was considered to be finalized when the subject accept- ed to participate in the study, answered the questionnaire and blood tests were performed according to the agreement. SEPHAR study is the first epidemiological study in Romania based on a representative sampling for the population of the entire country. It is the first study that evaluated simultaneously arterial hypertension and other cardiovascular
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