Neurological Sciences LE JOURNAL CANADIEN DES Sciences Neurologiques
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Volume 26 Number 4 November 1999 THE CANADIAN JOURNAL OF Neurological Sciences LE JOURNAL CANADIEN DES Sciences Neurologiques AN INTERNATIONAL JOURNAL / UN JOURNAL INTERNATIONAL REVIEW ARTICLE 255 EEG in Epilepsy: Current Perspectives M. Sundaram, R.M. Sadler, G.B. Young and N. Pillay ORIGINAL ARTICLES 263 Burden of Epilepsy: The Ontario Health Survey Samuel Wiebe, David R. Bellhouse, Christine Fallahay, Michael Eliasziw 271 Topiramate in Intractable Childhood Onset Epilepsy - A Cautionary Note J.M. Dooley, P.R. Cornfield, E. Smith, P. Langevin, G. Ronen 21A Consensus Statement of the Canadian MS Clinics Network on: The Use of Disease Modifying Agents in Multiple Sclerosis Joel Oger and Mark Freedman Dr. Charles G. Drake 1920-1998 276 Treatment with Interferon Beta- lb Improves Quality of Life in Multiple Sclerosis G.P. Rice, J. Oger, P. Duquette, G.S. Francis, M. Belanger, S. Laplante, J.F. Grenier 283 Responsiveness of the Scripps Neurologic Rating Scale During a Multiple Sclerosis Clinical Trial James A. Koziol, Adridna Lucero, Jack C. Sipe, John S. Romine, Ernest Beutler 290 MR Characteristics of Malignant Spinal Cord Astrocytomas in Children Abhaya V. Kulkarni, Derek C. Armstrong and James M. Drake 294 EMG Related Anxiety and Pain: A Prospective Study Mohammed M.S. Jan, Murray Schwartz, and Timothy J. Benstead EXPERIMENTAL NEUROSCIENCES 298 Biphasic Opening of the Blood-Brain Barrier Following Transient Focal Ischemia: Effects of Hypothermia Z. Gao Huang, Dong Xue, Edward Preston, Hasneen Karbalai, Alastair M. Buchan 305 Mevalonate Prevents Lovastatin-Induced Apoptosis in Medulloblastoma Cell Lines Wei Wang and Robert J.B. Macaulay Neuroimaging Highlight NEUROIMAGING HIGHLIGHT 311 Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) J.N. Scott, L. Metz, W.Y.Hu andM. Hudon CASE REPORTS 313 Utility of a Moveable 1.5 Tesla Intraoperative MR Imaging System: Case Report Taro Kaibara, John K. Saunders and Garnette R. Sutherland 317 Reversible Paraneoplastic Encephalomyelitis Associated with a Benign Ovarian Teratoma 35th CANADIAN R. Blaine Taylor, Warren Mason, Kester Kong, Richard Wennberg CONGRESS OF 321 Temporal Dermoid Cyst with a Partial Dermal Sinus Tract: A Case Report NEUROLOGICAL Joseph A. Shehadi, Ibrahim A. Alorainy, Karen M. Johnston SCIENCES 325 Acute Quadriplegic Myopathy Unrelated to Steroids or Paralyzing Agents: Quantitative EMG Studies June 13 - 17, 2000 Ahmet Hoke, N.B. Rewcastle and Douglas W. Zochodne Ottawa, Ontario IN MEMORIAM 330 Dr. Charles G. Drake 1920 - 1998 341 Canadian Association of Neuropathologists Abstracts of papers and cases presented at the 39th Annual Meeting SUPPLEMENT 3 SI The Scientific Basis of Migraine Management The official Journal of: The Canadian Neurological Society, The Canadian Neurosurgical Society, The Canadian Society of Clinical Neurophysiologists, The Canadian Association of Child Neurology Downloaded from https://www.cambridge.org/core. IP address: 170.106.35.93, on 24 Sep 2021 at 17:13:12, subject to the Cambridge Core terms of use, available at https://www.cambridge.org/core/terms. https://doi.org/10.1017/S0317167100050058 <$vv « »<?•«m&« YOU FOR>/ JIPKA.! LEVODORL Using RcQuip in ear!}' disease can sustain symptom control and has been shown to delay the need for ievodopa in the majority of patients (61 of 102) who completed a full 3 year study.M CONTINUED BENEFITS IN ADJUNCT THERAPY. RcQuip allowed a 20% or greater reduction in Ievodopa dose and also increased patients' 'on' time by 20% or more alter 6 months of combination therapy." SPARING LEVODOPA CAN DELAY COMPLICATIONS. Because ReQuip spares Ievodopa in both early and adjunct therapy, it can substantially reduce Ievodopa load for Parkinson's patients. As a result, ReQuip can delay and reduce long-term Ievodopa complications such as dyskinesias, 'on-off' effect and 'wearing off' effect.16 So starting ReQuip today can give Parkinsons patients a brighter outlook for tomorrow. +Mean dosage: 9.7 mg (SD 6.0) RcQuip (n«179), 464.0 rag (SD 266.0) l-dopa (n-89). 95% CI of 0.28, 2.26 Stage 1 or 1.5: 0.43, 3.07 Siage II; 0.04, 0.35 Stage II.5 or III. AMean UPDRS improvement in the non-selegilinc subgroup. Mean dosage: rropinirole 9.0 mg (SD 5.2) ReQuip (n«109), 17.2 mg (SD 8.8) bromocriptine (n.101). j^-X °P' 95% CI of 6.0%. 21.1%. 'Achieved by 28% of ropinirole (n*94) and 11% of placebo (n=54) treated B patients. 95% CI of 1.533, 12.658.' In early thetapy\ nausea (59.9%), dizziness (40.1%) and somnolence (40.1%) CST1 SmithKhne Beecham REQUIP were the most common side effects of ReQuip. Postural hypotension occurred l3ft# Pharma in 6.4% of patients. Thtrapy Jf^^J^ Tag In adjunct therapy with Ievodopa', dyskinesias (33.7%) and nausea (29.8%) were the most common side effects of ReQuip. |PAAB| C^h RIGHT FROM THE START. Downloaded from https://www.cambridge.org/core. IP address: 170.106.35.93, on 24 Sep 2021 at 17:13:12, subject to the Cambridge Core terms of use, available at https://www.cambridge.org/core/terms. https://doi.org/10.1017/S0317167100050058 For brief prescribing information see pages A-41, A-42 Volume 26 Number 4 November 1999 THE CANADIAN JOURNAL OF Neurological Sciences LE JOURNAL CANADIEN DES Sciences Neurologiques A-39 MESSAGE FROM THE EDITOR CASE REPORTS 313 Utility of a Moveable 1.5 Tesla Intraoperative MR Imaging REVIEW ARTICLE System: Case Report 255 EEG in Epilepsy: Current Perspectives Taw Kaibara, John K. Saunders and Garnette R. Sutherland M. Sundaram, R.M. Sadler, G.B. Young and N. Pillay 317 Reversible Paraneoplastic Encephalomyelitis Associated ORIGINAL ARTICLES with a Benign Ovarian Teratoma R. Blaine Taylor, Warren Mason, Kester Kong, 263 Burden of Epilepsy: The Ontario Health Survey Richard Wennberg Samuel Wiebe, David R. Bellhouse, Christine Fallahay, Michael Eliasziw 321 Temporal Dermoid Cyst with a Partial Dermal Sinus Tract: A Case Report 271 Topiramate in Intractable Childhood Onset Epilepsy - Joseph A. Shehadi, Ibrahim A. Alorainy, Karen M. Johnston A Cautionary Note J.M. Dooley, P.R. Camfleld, E. Smith, P. Langevin, 325 Acute Quadriplegic Myopathy Unrelated to Steroids or G. Ronen Paralyzing Agents: Quantitative EMG Studies Ahmet Hoke, N.B. Rewcastle and Douglas W. Zochodne 274 Consensus Statement of the Canadian MS Clinics Network on: The Use of Disease Modifying Agents in IN MEMORIAM Multiple Sclerosis 330 Dr. Charles G. Drake 1920 - 1998 Joel Oger and Mark Freedman Gary G. Ferguson and Vladimir C. Hachinski 276 Treatment with Interferon Beta-lb Improves Quality of 331 Perspectives from Dr. Charles Drake: Early Training in Toronto Life in Multiple Sclerosis Charles G. Drake G.P. Rice, J. Oger, P. Duquette, G.S. Francis, M. Belanger, S. Laplante, J.F. Grenier 335 Bleeding Aneurysms of the Basilar Artery. Direct Surgical Management in Four Cases 283 Responsiveness of the Scripps Neurologic Rating Scale Charles G Drake (Reprinted from the Journal of During a Multiple Sclerosis Clinical Trial Neurosurgery, 1961) James A. Koziol, Adriana Lucero, Jack C. Sipe, John S. Romine, Ernest Beutler 341 Canadian Association of Neuropathologists Abstracts of papers presented at the 39th Annual Meeting 290 MR Characteristics of Malignant Spinal Cord Astrocytomas in Children 346 Letter to the Editor Abhaya V. Kulkarni, Derek C. Armstrong and 347 Books Received James M. Drake 347 Book Reviews 294 EMG Related Anxiety and Pain: A Prospective Study 352 Notes and Announcements Mohammed M.S. Jan, Murray Schwartz, and Timothy J. Benstead 353 Calendar of Events 354 Index to Volume 26 EXPERIMENTAL NEUROSCIENCES A-6 Call for Abstracts - 35th Canadian 298 Biphasic Opening of the Blood-Brain Barrier Following Congress of Neurological Sciences Transient Focal Ischemia: Effects of Hypothermia Z. Gao Huang, Dong Xue, Edward Preston, A-12 Preliminary Program - 35th Canadian Hasneen Karbalai, Alastair M. Buchan Congress of Neurological Sciences A-20, A-26 1999 Society Prize Announcements 305 Mevalonate Prevents Lovastatin-Induced Apoptosis in Medulloblastoma Cell Lines A-40 Information for Authors Wei Wang and Robert J.B. Macaulay A-18, A-32 25 Years Ago in the Canadian Journal of Neurological Sciences NEUROIMAGING HIGHLIGHT A-73 Advertisers Index 311 Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) SUPPLEMENT 3 J.N. Scott, L. Metz, W.Y.Hu andM. Hudon S1-S43 The Scientific Basis of Migraine Management Downloaded from https://www.cambridge.org/core. IP address: 170.106.35.93, on 24 Sep 2021A-l at 17:13:12, subject to the Cambridge Core terms of use, available at https://www.cambridge.org/core/terms. https://doi.org/10.1017/S0317167100050058 Volume 26 Number 4 November 1999 THE CANADIAN JOURNAL OF Neurological Sciences LE JOURNAL CANADIEN DES Sciences Neurologiques Editor/Redacteur en chef The official journal of: / La Revue offlcielle de: Douglas W. Zochodne CALGARY, AB The Canadian Neurological Society La Societe Canadienne de Neurologie Associate Editors/Redacteurs associes The Canadian Neurosurgical Society Laurence E. Becker TORONTO, ON La Societe Canadienne de Neurochirurgie The Canadian Society of Clinical Neurophysiologists Andres M. Lozano TORONTO, ON La Societe Canadienne de Neurophysiologie Clinique The Canadian Association of Child Neurology Past Editors L'Association Canadienne de Neurologie Pediatrique James A. Sharpe TORONTO, ON The permanent secretariat for the four societies and the Canadian Robert G. Lee CALGARY, AB Congress of Neurological Sciences is at/ Robert T. Ross WINNIPEG, MB Le secretariat des quatre associations et du Congres Canadien des Sciences Neurologiques est situe en permanence a: (founding editor) 810, 906 - 12 Avenue S.W., Calgary, AB Canada T2R 1K7 Editorial Board/Conseil Scientifique The Canadian Journal of Neurological Sciences is published quarterly. The Harold P. Adams IOWA CITY, IA, USA annual subscription rate is $70 for members; $77 for non-members in Canada; Jack P. Antel MONTREAL, QC $88 for USA and elsewhere. Residents.