New Radiation Tools and Techniques for Cancer Treatment
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Investigation Study Radiation Profile on a 20 Gbq Therasphere Dose Vial
Attachment 14 NUCLEAR MEDICINE M Nordion KANATA OPERATIONS INVESTIGATION STUDY PD99099003.08 Page No: I of 4 Investigation Study Radiation Profile on a 20 GBq TheraSphere Dose Vial I Signatures Prepared by: Date: ý - Al -; Approved by:. Date: 2•-O--c "Y (Richard Decaire CAHT) Document History Date Version''• •Comments Prepared by . Reviewed by Approved by PD99099003.08 Page Investigation No: 2 of 4 Study Radiation Profile on a 20 GBq TheraSphere Dose Vial 1. INTRODUCTION The United States Nuclear Regulatory Commission had requested information to support MDS Nordion application for the registration of TheraSphere. This request is contained in a letter dated November 23, 1999 from a Dr John P. Jankovich. This report contains data collected to address question 7 parts a, b, and c. The question poised is as follows: "Regarding external radiation levels, NRC needs information on the device itself, not on the radiation levels around the patient as addressed in the application. Therefore, please specify: a. External radiation levels around the lucite vial containing the maximum dose of 20 GBq (540 mCi). Provide the data, preferably, at the surface, and at 5, 30, and 100 cm. If there are no meaningful readings at these locations, please state so. b. Provide similar external radiation levels, if any, outside the lead pot with the lucite vial inside containing a maximum dose of microspheres. c. Please specify the instrument which you used to perform the radiation profile measurements by listing the instrument manufacturers, model numbers, calibration dates, sensitivity, etc." To address these questions, information was provided from previous development work. -
3Rd Quarter 2001 Bulletin
In This Issue... Promoting Colorectal Cancer Screening Important Information and Documentaion on Promoting the Prevention of Colorectal Cancer ....................................................................................................... 9 Intestinal and Multi-Visceral Transplantation Coverage Guidelines and Requirements for Approval of Transplantation Facilities12 Expanded Coverage of Positron Emission Tomography Scans New HCPCS Codes and Coverage Guidelines Effective July 1, 2001 ..................... 14 Skilled Nursing Facility Consolidated Billing Clarification on HCPCS Coding Update and Part B Fee Schedule Services .......... 22 Final Medical Review Policies 29540, 33282, 67221, 70450, 76090, 76092, 82947, 86353, 93922, C1300, C1305, J0207, and J9293 ......................................................................................... 31 Outpatient Prospective Payment System Bulletin Devices Eligible for Transitional Pass-Through Payments, New Categories and Crosswalk C-codes to Be Used in Coding Devices Eligible for Transitional Pass-Through Payments ............................................................................................ 68 Features From the Medical Director 3 he Medicare A Bulletin Administrative 4 Tshould be shared with all General Information 5 health care practitioners and managerial members of the General Coverage 12 provider/supplier staff. Hospital Services 17 Publications issued after End Stage Renal Disease 19 October 1, 1997, are available at no-cost from our provider Skilled Nursing Facility -
Chapter 5: Treatment Machines for External Beam Radiotherapy
Chapter 5: Treatment Machines for External Beam Radiotherapy Set of 126 slides based on the chapter authored by E.B. Podgorsak of the IAEA publication: Radiation Oncology Physics: A Handbook for Teachers and Students Objective: To familiarize the student with the basic principles of equipment used for external beam radiotherapy. Slide set prepared in 2006 by E.B. Podgorsak (Montreal, McGill University) Comments to S. Vatnitsky: [email protected] IAEA International Atomic Energy Agency CHAPTER 5. TABLE OF CONTENTS 5.1. Introduction 5.2. X-ray beams and x-ray units 5.3. Gamma ray beams and gamma ray units 5.4. Particle accelerators 5.5. Linacs 5.6. Radiotherapy with protons, neutrons, and heavy ions 5.7. Shielding considerations 5.8. Cobalt-60 teletherapy units versus linacs 5.9. Simulators and computed tomography simulators 5.10. Training requirements IAEA Radiation Oncology Physics: A Handbook for Teachers and Students - 5.1 Slide 1 5.1 INTRODUCTION The study and use of ionizing radiation in medicine started with three important discoveries: • X rays by Wilhelm Roentgen in 1895. • Natural radioactivity by Henri Becquerel in 1896. • Radium-226 by Pierre and Marie Curie in 1898. IAEA Radiation Oncology Physics: A Handbook for Teachers and Students - 5.1 Slide 1 5.1 INTRODUCTION Immediately upon the discovery of x rays and natural radioactivity, ionizing radiation has played an important role in: • Atomic and nuclear physics from the basic physics point of view. • In medicine providing an impetus for development of radiology and radiotherapy as medical specialties and medical physics as a specialty of physics. -
Variations in the Practice of Molecular Radiotherapy and Implementation Of
Sjögreen Gleisner et al. EJNMMI Physics (2017) 4:28 EJNMMI Physics DOI 10.1186/s40658-017-0193-4 ORIGINAL RESEARCH Open Access Variations in the practice of molecular radiotherapy and implementation of dosimetry: results from a European survey Katarina Sjögreen Gleisner1* , Emiliano Spezi2, Pavel Solny3, Pablo Minguez Gabina4, Francesco Cicone5, Caroline Stokke6, Carlo Chiesa7, Maria Paphiti8, Boudewijn Brans9, Mattias Sandström10, Jill Tipping11, Mark Konijnenberg12 and Glenn Flux13 * Correspondence: [email protected] Abstract 1Department of Medical Radiation Physics, Clinical Sciences Lund, Background: Currently, the implementation of dosimetry in molecular radiotherapy Lund University, Lund, Sweden (MRT) is not well investigated, and in view of the Council Directive (2013/59/Euratom), Full list of author information is there is a need to understand the current availability of dosimetry-based MRT in clinical available at the end of the article practice and research studies. The aim of this study was to assess the current practice of MRT and dosimetry across European countries. Methods: An electronic questionnaire was distributed to European countries. This addressed 18 explicitly considered therapies, and for each therapy, a similar set of questions were included. Questions covered the number of patients and treatments during 2015, involvement of medical specialties and medical physicists, implementation of absorbed dose planning, post-therapy imaging and dosimetry, and the basis of therapy prescription. Results: Responses were obtained from 26 countries and 208 hospitals, administering in total 42,853 treatments. The most common therapies were 131I-NaI for benign thyroid diseases and thyroid ablation of adults. The involvement of a medical physicist (mean over all 18 therapies) was reported to be either minority or never by 32% of the responders. -
Implantable Beta-Emitting Microspheres for Treatment of Malignant Tumors
UnitedHealthcare® Commercial Medical Policy Implantable Beta-Emitting Microspheres for Treatment of Malignant Tumors Policy Number: 2021T0445S Effective Date: August 1, 2021 Instructions for Use Table of Contents Page Related Commercial Policy Coverage Rationale ........................................................................... 1 • Abnormal Uterine Bleeding and Uterine Fibroids Documentation Requirements......................................................... 1 Definitions ........................................................................................... 2 Community Plan Policy Applicable Codes .............................................................................. 2 • Implantable Beta-Emitting Microspheres for Treatment of Malignant Tumors Description of Services ..................................................................... 3 Clinical Evidence ............................................................................... 3 Medicare Advantage Coverage Summary U.S. Food and Drug Administration ..............................................15 • Brachytherapy Procedures References .......................................................................................15 Policy History/Revision Information..............................................18 Instructions for Use .........................................................................19 Coverage Rationale Transarterial radioembolization (TARE) using yttrium-90 (90Y) microspheres is proven and medically necessary for the following: • When used -
A Retrospective of Cobalt-60 Radiation Therapy: “The Atom Bomb That Saves Lives”
MEDICAL PHYSICS INTERNATIONAL Journal, Special Issue, History of Medical Physics 4, 2020 A RETROSPECTIVE OF COBALT-60 RADIATION THERAPY: “THE ATOM BOMB THAT SAVES LIVES” J. Van Dyk1, J. J. Battista1, and P.R. Almond2 1 Departments of Medical Biophysics and Oncology, Western University, London, Ontario, Canada 2 University of Texas, MD Anderson Cancer Center, Houston, Texas, United States Abstract — The first cancer patients irradiated with CONTENTS cobalt-60 gamma rays using external beam I. INTRODUCTION radiotherapy occurred in 1951. The development of II. BRIEF HISTORY OF RADIOTHERAPY cobalt-60 machines represented a momentous III. LIMITATIONS OF RADIATION THERAPY breakthrough providing improved tumour control UNTIL THE 1950s and reduced complications, along with much lower skin reactions, at a relatively low cost. This article IV. RADIOACTIVE SOURCE DEVELOPMENT provides a review of the historic context in which the V. THE RACE TO FIRST CANCER TREATMENTS advances in radiation therapy with megavoltage VI. COBALT TRUTHS AND CONSEQUENCES gamma rays occurred and describes some of the VII. COBALT TELETHERAPY MACHINE DESIGNS physics and engineering details of the associated VIII. GROWTH AND DECLINE OF COBALT-60 developments as well as some of the key locations and TELETHERAPY people involved in these events. It is estimated that IX. COBALT VERSUS LINAC: COMPETING over 50 million patients have benefited from cobalt-60 teletherapy. While the early growth in the use of MODALITIES cobalt-60 was remarkable, linear accelerators (linacs) X. OTHER USES OF COBALT-60 provided strong competition such that in the mid- XI. SUMMARY AND CONCLUSIONS 1980s, the number of linacs superseded the number of ACKNOWLEDGEMENTS cobalt machines. -
Of Richard Martin on Yttrium-90 Microsphere Brachytherapy
Page 1 of 1 As of: 2/8/18 2:05 PM Received: February 08, 2018 Status: Pending~Post PUBLIC SUBMISSION Tracking No. lk2-91du-ys8n Comments Due: February 08, 2018 Submission Type: Web Docket: NRC-2017-0215 Yttrium-90 Microsphere Brachytherapy Sources and Devices Therasphere and SIR-Spheres Comment On: NRC-2017-0215-0024 Yttrium-90 Microsphere Brachytherapy Sources and Devices TheraSphere and SIR-Spheres; Draft Guidance; Extension of Comment Period Document: NRC-2017-0215-DRAFT-0132 Comment on FR Doc# 2017-28271 Submitter Information Name: Richard Martin Organization: American Association of Physicists in Medicine General Comment See attached file(s) Attachments AAPM Comment NRC Y-90 Guidance Final RM SUNSI Review Complete Template= ADM - 013 E-RIDS= ADM-03 · Add= l.1 SCA.\), m )11 1lJ:. C) lch) K~~-t.ri11"1 MP.P ( Kris!) https://www.fdms.gov/fdms/getcontent?objectld=0900006482f01e40&format=xml&showorig=false 02/08/2018 ''l, :~:~~.::. ' ••• ·: ·.~ ••~ ~ •'<",• ··:. : •• · 1 • ~ • • • • • ' • • • j db AMERICAN ASSOCIATION ~l7ef PHYSICISTS IN MEDICINE February 8, 2018 May Ma Office of Administration Mail Stop: OWFN-2-A13 U.S. Nuclear Regulatory Commission Washington, DC 20555-0001 RE: Request for Comment: Yttrium-90 Microsphere Brachytherapy Sources and Devices TheraSphere and SIR-Spheres Draft Guidance (NRC-2017-0215) Dear Ms. Ma: The American Association of Physicists in Medicine (AAPM)1 is pleased to submit comments to the U.S. Nuclear Regulatory Commission (NRC) regarding Yttrium-90 Microsphere Brachytherapy Sources and Devices TheraSphere and SIR-Spheres Draft Licensing Guidance (Revision 10). The AAPM commends the NRC on its work in providing the NRC with a set of standard criteria for evaluating a medical use license application for the use of TheraSpheres and SIR-Spheres. -
MG Selective Internal Radiation Therapy
Selective Internal Radiation Therapy Last Review Date: May 7, 2021 Number: MG.MM.RA.12d Medical Guideline Disclaimer Property of EmblemHealth. All rights reserved. The treating physician or primary care provider must submit to EmblemHealth the clinical evidence that the patient meets the criteria for the treatment or surgical procedure. Without this documentation and information, EmblemHealth will not be able to properly review the request for prior authorization. The clinical review criteria expressed below reflects how EmblemHealth determines whether certain services or supplies are medically necessary. EmblemHealth established the clinical review criteria based upon a review of currently available clinical information (including clinical outcome studies in the peer reviewed published medical literature, regulatory status of the technology, evidence-based guidelines of public health and health research agencies, evidence-based guidelines and positions of leading national health professional organizations, views of physicians practicing in relevant clinical areas, and other relevant factors). EmblemHealth expressly reserves the right to revise these conclusions as clinical information changes and welcomes further relevant information. Each benefit program defines which services are covered. The conclusion that a particular service or supply is medically necessary does not constitute a representation or warranty that this service or supply is covered and/or paid for by EmblemHealth, as some programs exclude coverage for services or supplies that EmblemHealth considers medically necessary. If there is a discrepancy between this guideline and a member's benefits program, the benefits program will govern. In addition, coverage may be mandated by applicable legal requirements of a state, the Federal Government or the Centers for Medicare & Medicaid Services (CMS) for Medicare and Medicaid members. -
Radiation Dose in Radiotherapy from Prescription to Delivery
IAEA-TECDOC-896 XA9642841 Radiation dose in radiotherapy from prescription to delivery INTERNATIONAL ATOMIC ENERGY AGENCY The originating Section of this publication in the IAEA was: Dosimetry Section International Atomic Energy Agency Wagramerstrasse 5 P.O. Box 100 A-1400 Vienna, Austria RADIATION DOSE IN RADIOTHERAPY FROM PRESCRIPTION TO DELIVERY IAEA, VIENNA, 1996 IAEA-TECDOC-896 ISSN 1011-4289 © IAEA, 1996 Printed by the IAEA in Austria August 1996 The IAEA does not normally maintain stocks of reports in this series. However, microfiche copies of these reports can be obtained from INIS Clearinghouse International Atomic Energy Agency Wagramerstrasse 5 P.O. Box 100 A-1400 Vienna, Austria Orders should be accompanied by prepayment of Austrian Schillings 100, in the form of a cheque or in the form of IAEA microfiche service coupons which may be ordered separately from the INIS Clearinghouse. FOREWORD Cancer incidence is increasing in developed as well as in developing countries. However, since in some advanced countries the cure rate is increasing faster than the cancer incidence rate, the cancer mortality rate is no longer increasing in such countries. The increased cure rate can be attributed to early diagnosis and improved therapy. On the other hand, until recently, in some parts of the world - particularly in developing countries - cancer control and therapy programmes have had relatively low priority. The reason is the great need to control communicable diseases. Today a rapidly increasing number of these diseases are under control. Thus, cancer may be expected to become a prominent problem and this will result in public pressure for higher priorities on cancer care. -
Nuclear Physics for Medicine
Nuclear Physics European Collaboration Committee (NuPECC) Nuclear Physics for Medicine European Science Foundation (ESF) Nuclear Physics European Collaboration The European Science Foundation (ESF) was Committee (NuPECC) established in 1974 to provide a common platform NuPECC is an Expert Committee of the European for its Member Organisations to advance European Science Foundation. The aim of NuPECC is to research collaboration and explore new directions for strengthen collaboration in nuclear science by research. It is an independent organisation, owned by promoting nuclear physics, and its trans-disciplinary 66 Member Organisations, which are research funding use and application, in collaborative ventures between organisations, research performing organisations European research groups, and particularly those from and academies from 29 countries. ESF promotes countries linked to the European Science Foundation collaboration in research itself, in funding of research (ESF). NuPECC encourages the optimal use of a and in science policy activities at the European level. network of complementary facilities across Europe, Currently ESF is reducing its research programmes provides a forum for discussing the provision of future while developing new activities to serve the science facilities and instrumentation, and advises and makes community, including peer review and evaluation recommendations to the ESF and other bodies on the services. development, organisation, and support of European nuclear research, particularly on new projects. The -
Radiation Therapy Cancer
TYPES OF RADIATION ABOUT OHC THERAPY OFFERED At OHC, the search for new treatments is relentless, THROUGH OHC’S the drive to provide superior care runs deep and the COMPREHENSIVE fight against cancer is personal. Our independent, PROGRAM physician-led practice is recognized for going beyond clinical excellence, providing unrestricted • 3-D conformal – Three-dimensional treatment personal support and genuine emotional caring • Cesium - 131 Brachytherapy in neighborhood locations throughout the region. • CyberKnife Robotic Radiosurgery System OHC has been fighting cancer on the front lines • Gamma Knife Radiosurgery (Administered for more than three decades. At its heart, our exclusively through OHC) approach to cancer care is simple – we treat you like • HDR Brachytherapy – Internal Radiation family and surround you with everything you need so you can focus on what matters most: beating • IGRT – Image Guided Radiation Therapy cancer. • IMRT – Intensity Modulated Radiation Therapy • SBRT – Stereotactic Body Radiation Therapy • SRS – Stereotactic Radiosurgery • TheraSphere • Xofigo With a combined approach, you and your OHC radiation doctor will determine which type of RADIATION treatment is best for your diagnosis. To learn more about OHC’s radiation oncology services, please call 1-888-649-4800 or visit ohcare.com. THERAPY For more information, call toll free OHC radiation oncologists harness the power of 1-888-649-4800 or visit ohcare.com. advanced technology for targeted cancer care OHC. Start here. Research Nurses: Specially-trained registered nurses who work directly with a patient’s doctor to coordinate care and treatment if you are participating in a clinical trial . Medical Assistant: The person who takes your vital signs and completes an assessment before WHAT IS RADIATION you see the doctor THERAPY? . -
Commercial Radioactive Sources
Commercial Radioactive CNS Sources: Surveying the OCCASIONAL PAPER #11 JANUARY 2003 Security Risks Charles D. Ferguson, Tahseen Kazi, Judith Perera THE CENTER FOR NONPROLIFERATION STUDIES The mission of the Center for Nonproliferation Studies (CNS) is to combat the spread of weapons of mass destruction by training the next generation of nonproliferation specialists and disseminating timely information and analysis. Dr. William C. Potter is the director of CNS, which has a staff of more than 60 full-time personnel and approximately 75 student research assistants, with offices in Monterey, CA; Washington, DC; and Almaty, Kazakhstan. CNS is the largest nongovernmental organization in the United States devoted exclusively to research and training on nonproliferation issues. CNS gratefully acknowledges the support of the following funders and thanks them for their commitment to our mission: the Carnegie Corporation of New York, the Center for Global Partnership, the Compton Foundation, the Ford Foundation, the Japan-United States Friendship Commission, the John D. and Catherine T. MacArthur Foundation, the Nuclear Threat Initiative, the Ploughshares Fund, the Prospect Hill Foundation, and the Scherman Foundation. For more information on the projects and publications of CNS, contact: Center for Nonproliferation Studies Monterey Institute of International Studies 460 Pierce Street Monterey, California 93940 USA Tel: 831.647.4154 Fax: 831.647.3519 E-mail: [email protected] Website: http://cns.miis.edu CNS Publications Staff Editor-in-Chief Editor Copy Editor Leonard S. Spector Scott Parrish Bill Gibson Managing Editor Cover Design Lisa Donohoe Cutting Edge Design, Washington, DC Cover photos: Background photo: Radioactive sources that were used in mobile irradiators in the former Soviet Union and that contain 3,500 curies of cesium-137; photo credit: IAEA.