Curriculum Vitae November 2015 GREGORY B. MARTIN

Professor Section of Plant Pathology and Plant-Microbe School of Integrative Plant Science Email: [email protected] Tel.: (607) 254-1208 Ithaca, NY 14853 Fax: (607) 254-1242

Boyce Schulze Downey Professor Boyce Thompson Institute for Plant Research Ithaca, NY 14853

RESEARCH & TEACHING EXPERTISE Molecular basis of bacterial infection processes – Molecular basis of plant immunity and disease susceptibility – Application of genomics approaches to gene discovery in bacterial pathogens and plants

EDUCATION 1989 – 1992 Postdoctoral Fellow Cornell University 1989 Ph.D. Genetics Michigan State University 1984 M.S. Plant Breeding Michigan State University 1979 B.S. Crop & Soil Science Michigan State University

ACADEMIC RANKS 2005 – Present Boyce Schulze Downey Professor, Boyce Thompson Institute for Plant Research 1998 – Present Professor, Department of Plant Pathology and Plant-Microbe Biology, Cornell University 2014 Acting President, Boyce Thompson Institute for Plant Research 2011 – 2014 Honorary Distinguished Professor of Biological Sciences, King Abdulaziz University, Saudi Arabia 1998 – 2005 Professor, Boyce Thompson Institute for Plant Research 1996 – 1998 Associate Professor, Department of Agronomy, 1992 – 1996 Assistant Professor, Department of Agronomy, Purdue University

PROFESSIONAL EXPERIENCE 1989 – 1992 NSF Postdoctoral Fellow, Department of Plant Breeding & Genetics, Cornell University 1985 – 1989 Graduate Fellow, Genetics Program, DOE Plant Research Laboratory, Michigan State University 1984 – 1985 Graduate Assistant, Department of Crop Science, North Carolina State University 1982 – 1983 Research Scientist, U.S. Agency for International Development (USAID), University of Malawi – Bunda College of Agriculture, Lilongwe, Malawi 1981 – 1984 Graduate Assistant, Department of Crop and Soil Science, Michigan State University

HONORS / PROFESSIONAL RECOGNITION 2014 John and Olga LeTourneau Memorial Lecturer, University of Idaho 2011 Honorary Distinguished Professor, King Abdulaziz University, Jeddah, Saudi Arabia 2010 Noel Keen Award for Excellence in Molecular Plant Pathology, American Phytopathological Society 2010 Daniel F. Milikan Memorial Lecturer, University of Missouri 2006 Grand Marnier Foundation Lecturer, Pasteur Institute, Paris 2005 Boyce Schulze Downey Professor, Boyce Thompson Institute for Plant Research 2005 Fellow, American Academy of Microbiology 2005 Ad hoc Advisor, MacArthur Foundation Fellows Program 2004 An ISI Most Highly Cited Author (Plant and Animal Science) (http://isihighlycited.com) 2004 Fellow, American Association for the Advancement of Science (AAAS)

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2004 Ad hoc Advisor, Spinoza Foundation, Hague, Netherlands 2004 ISI 3rd Most Highly Cited Paper in Plant and Animal Science (http://www.in-cites.com/papers/DrGregMartin.html) 2000 Roger E. Koeppe Endowed Lecture, Oklahoma State University 1997 Herbert Newby McCoy Award for Outstanding Research, Purdue University 1997 Barry Chelm Memorial Lecturer, Michigan State University 1995 – 2000 David and Lucile Packard Fellowship in Science and Engineering 1989 – 1992 NSF Postdoctoral Fellowship in Plant Biology 1985 – 1988 USDA National Needs in Biotechnology Predoctoral Fellowship

BIOGRAPHICAL SKETCH Gregory B. Martin received his B.S. (1979), M.S. (1984) and Ph.D. (1989) from Michigan State University. After obtaining his Ph.D. in Genetics, Martin was awarded an NSF Plant Biology Fellowship to conduct postdoctoral research at Cornell University with Prof. Steve Tanksley. At Cornell, Martin began his research on the interaction between tomato and the bacterial pathogen, Pseudomonas syringae pv. tomato. As part of this work, he developed methods for using genetic linkage maps to isolate genes from tomato and cloned the Pto gene which confers immunity to bacterial speck disease. Martin accepted a faculty position at Purdue University in 1992 where he taught undergraduate genetics and continued his research on the Pseudomonas-tomato system. In 1998, Martin accepted a joint appointment at the Boyce Thompson Institute for Plant Research (BTI) and the Department of Plant Pathology and Plant-Microbe Biology at Cornell University. He is currently a professor at Cornell University, the Boyce Schulze Downey Professor at BTI, and is a Fellow of the American Academy of Microbiology and the American Association for the Advancement of Science (AAAS). Martin teaches an undergraduate course titled “Innate immunity in Plants, Flies, and Humans” and a graduate course on “Molecular plant-microbe interactions” and operates a laboratory focused on understanding the mechanisms underlying bacterial infection processes and plant immunity. Website: http://bti.cornell.edu/staff/martin-gregory/

PUBLICATIONS - SELECTED (from ~145 total)

For all publications, see: Google Scholar: http://scholar.google.com/citations?user=_rVi7FUAAAAJ&hl=en&oi=ao ResearchID: http://www.researcherid.com/rid/F-6262-2011

1. Bao, Z., F. Meng, S. R. Strickler, D. M. Dunham, K. R. Munkvold and G. B. Martin (2015). Identification of a candidate gene in Solanum habrochaites for resistance to a race 1 strain of Pseudomonas syringae pv. tomato. The Plant Genome, in press. 2. Jacobs, T. B. and G. B. Martin (2015). High-throughput CRISPR vector construction and generation of tomato hairy roots for the characterization of DNA modifications. Journal of Visualized Experiments, in press. 3. Wei H. L., S. Chakravarthy, J. Mathieu, T. C. Helmann, P. Stodghill, B. Swingle, G. B. Martin* and A. Collmer* (2015). Pseudomonas syringae pv. tomato DC3000 type III secretion effector polymutants reveal an interplay between HopAD1 and AvrPtoB. Cell Host Microbe 17(6):752-62. *co-corresponding authors. 4. Boyle P.C. and G. B. Martin (2015). Greasy tactics in the plant-pathogen molecular arms race. J. Experimental Botany 66:1607-16. 5. Fernandez-Pozo N., H. G. Rosli, G. B. Martin and L. A. Mueller (2015). The SGN VIGS tool: User-friendly software to design virus-induced gene silencing (VIGS) constructs for functional genomics. Molecular Plant 8:486-8. 6. Pombo M. A., Y. Zheng, N. Fernandez-Pozo, D. M. Dunham, Z. Fei and G. B. Martin (2014). Transcriptomic analysis reveals tomato genes whose expression is induced specifically during effector-triggered immunity and identifies the Epk1 protein kinase which is required for the host response to three bacterial effector proteins. Genome Biology 15:492. 7. Mathieu J., S. Schwizer and G. B. Martin (2014). Pto kinase binds two domains of AvrPtoB and its proximity to the effector E3 ligase determines if it evades degradation and activates plant immunity. PLoS Pathogens 10:e1004227.

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8. Rosli H. G., Y. Zheng, M.A. Pombo, S. Zhong, A. Bombarely, Z. Fei, A. Collmer and G. B. Martin (2013). Transcriptomics-based screen for genes induced by flagellin and repressed by pathogen effectors identifies a cell wall- associated kinase involved in plant immunity. Genome Biology 14:R139. 9. de la Torre, F., E. Gutiérrez-Beltrán,Y. Pareja-Jaime, S. Chakravarthy, G. B. Martin and O. del Pozo (2013). The tomato calcium sensor Cbl10 and its interacting protein kinase Cipk6 define a signaling pathway in plant immunity. Plant Cell 25:2748-2764. 10. Mural, R.V., Y. Liu, T. R. Rosebrock, J. J. Brady, S. Hamera, R. A. Connor, G. B. Martin and L. Zeng (2013). The tomato Fni3 lysine-63-specific ubiquitin-conjugating enzyme and Suv ubiquitin E2 variant positively regulate plant immunity. Plant Cell 25:3615-3631. 11. Chien, C.-F., J. Mathieu, C.-H. Hsu, P. Boyle, G. B. Martin and N.-C. Lin (2013). Nonhost resistance of tomato to the bean pathogen Pseudomonas syringae pv. syringae B728a is due to a defective E3 ubiquitin ligase domain in AvrPtoBB728a. Molecular Plant-Microbe Interactions 26:387-397. 12. Bombarely, A., H. G. Rosli, J. Vrebalov, P. Moffett, L. A. Mueller and G. B. Martin (2012). A draft genome sequence of Nicotiana benthamiana to enhance molecular plant-microbe biology research. Molecular Plant-Microbe Interactions 25:1523-1530. 13. Zeng L., A. C. Velasquez, K. R. Munkvold, J. Zhang, and G. B. Martin (2012). A tomato LysM receptor-like kinase promotes immunity and its kinase activity is inhibited by AvrPtoB. Plant Journal 69:92-103. 14. Cheng, W., K. R. Munkvold, H. Gao, J. Mathieu, S. Schwizer, S. Wang, Y.-B. Yan, J. Wang, G. B. Martin and J. Chai (2011). Structural analysis of Pseudomonas syringae AvrPtoB bound to host BAK1 reveals two similar kinase- interacting domains in a type III effector. Cell Host & Microbe 10:616-26. 15. Cunnac S., S. Chakravarthy, B. H. Kvitko, A. B. Russell, G. B. Martin and A. Collmer (2011). Genetic disassembly and combinatorial reassembly identify a minimal functional repertoire of type III effectors in Pseudomonas syringae pv. tomato DC3000. Proceedings of the National Academy of the Science USA 108:2975-80. 16. Oh, C.-S. and G. B. Martin (2011). Effector-triggered immunity mediated by the Pto kinase. Trends in Plant Science 16:132-40. 17. Chakravarthy, S., A. C. Velasquez, S. K. Ekengren, A. Collmer and G. B. Martin (2010). Identification of Nicotiana benthamiana genes involved in pathogen-associated molecular pattern-triggered immunity. Molecular Plant-Microbe Interactions 23:715-726. 18. Nguyen, H.P., S. Chakravarthy, A. C. Velasquez, H. L. McLane, L. Zeng, H. Nakayashiki, D. H. Park, A. Collmer and G. B. Martin (2010). Methods to study PAMP-triggered immunity using tomato and Nicotiana benthamiana. Molecular Plant-Microbe Interactions 23:991-999. 19. Oh, C.-S., K. F. Pedley and G. B. Martin (2010). Tomato 14-3-3 protein 7 positively regulates immunity-associated programmed cell death by enhancing protein abundance and signaling ability of MAPKKKa. Plant Cell 22:260-72. 20. Yeam I, H. P. Nguyen and G. B. Martin (2010). Phosphorylation of the Pseudomonas syringae effector AvrPto is required for FLS2/BAK1-independent virulence activity and recognition by tobacco. Plant Journal 61:16-24. 21. Dong, J., F. Xiao, F. Fan, L. Gu, H. Cang, G. B. Martin and J. Chai (2009). Crystal structure of the complex between Pseudomonas effector AvrPtoB and the tomato Pto kinase reveals both a shared and a unique interface compared with AvrPto-Pto. Plant Cell 21:1846-1859. 22. Kvitko, B. H., A. C. Velásquez, C.-F. Wei, A. B. Russell, G. B. Martin, D. J. Schneider and A. Collmer (2009). Deletions in the repertoire of Pseudomonas syringae pv. tomato DC3000 type III secretion effector genes reveal functional overlap among effectors. PLoS Pathogens 5:e1000388. 23. Shan L., P. He, J. Li, A. Heese, S. Peck, T. Nürnberger, G. B. Martin and J. Sheen (2008). Bacterial effectors target BAK1 to disrupt MAMP receptor signaling complexes and impede plant innate immunity. Cell Host-Microbe 4:17- 27. 24. Lin, N.-C. and G. B. Martin (2007). Pto- and Prf-mediated recognition of AvrPto and AvrPtoB restricts the ability of diverse Pseudomonas syringae pathovars to infect tomato. Molecular Plant-Microbe Interactions 20:806-815. 25. Rosebrock, T. R., L. Zeng, J. J. Brady, R. B. Abramovitch, F. Xiao and G. B. Martin (2007). A bacterial E3 ubiquitin ligase targets a host protein kinase to disrupt plant immunity. Nature 448:370-374. 26. Wei, C.-F., B. H. Kvitko, R. Shimizu, E. Crabill, J. R. Alfano, N.-C. Lin, G. B. Martin, H.-C. Huang and A. Collmer (2007). A Pseudomonas syringae pv. tomato DC3000 mutant lacking the type III effector HopQ1-1 is able to cause disease in the model plant Nicotiana benthamiana. Plant Journal 51:32-46.

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27. Xiao, F., P. He, R. B. Abramovitch, J. E. Dawson, L. K. Nicholson, J. Sheen and G. B. Martin (2007). The N-terminal region of Pseudomonas type III effector AvrPtoB elicits Pto-dependent immunity and has two distinct virulence determinants. Plant Journal 52:595-614. 28. Abramovitch, R. B., R. Janjusevic, C. E. Stebbins and G. B. Martin (2006). Type III effector AvrPtoB requires intrinsic E3 ubiquitin ligase to suppress plant cell death and immunity. Proceedings of the National Academy of Sciences USA 103:2851-2856. 29. Abramovitch, R. B., J. C. Anderson and G. B. Martin. 2006. Bacterial elicitation and evasion of plant innate immunity. Nature Reviews Molecular Cell Biology 7: 601-611. 30. Anderson, J. C., P. E. Pascuzzi, F. Xiao, G. Sessa and G. B. Martin (2006). Host-mediated phosphorylation of type III effector AvrPto promotes Pseudomonas virulence and avirulence in tomato. Plant Cell 18:502-514. 31. Devarenne, T. P., S. K. Ekengren, K. F. Pedley and G. B. Martin (2006). Adi3 is a Pdk1-interacting AGC kinase that negatively regulates plant cell death. EMBO Journal 25:255-265. 32. He, P., L. Shan, N.-C. Lin, G. B. Martin, B. Kemmerling, T. Nurnberger and J. Sheen (2006). Specific bacterial suppressors of MAMP signaling upstream of MAPKKK in Arabidopsis innate immunity. Cell 125:563-575. 33. Janjusevic, R., R. B. Abramovitch, G. B. Martin* and C. E. Stebbins* (2006). A bacterial inhibitor of host programmed cell death defenses is an E3 ubiquitin ligase. Science 311: 222-226. *Co-corresponding authors. 34. Lin, N.-C. and G. B. Martin (2005). An avrPto/avrPtoB mutant of Pseudomonas syringae pv. tomato DC3000 does not elicit Pto-mediated resistance and is less virulent on tomato. Molecular Plant-Microbe Interactions 18: 43-51. 35. Pedley, K. F. and G. B. Martin (2005). Role of mitogen-activated protein kinases in plant immunity. Current Opinions in Plant Biology 8:541-547. 36. Burch-Smith, T. M., J. C. Anderson and G. B. Martin and S. P. Dinesh-Kumar (2004). Applications and advantages of virus-induced gene silencing (VIGS) for gene function studies in plants. Plant Journal 39:734-746. 37. del Pozo, O., K. F. Pedley and G. B. Martin (2004). MAPKKKa is a positive regulator of cell death associated with both plant immunity and disease susceptibility. EMBO Journal 23:3072-3082. 38. Abramovitch, R.B., Y.-J. Kim, S. Chen, M. B. Dickman and G. B. Martin (2003). Pseudomonas type III effector AvrPtoB induces plant disease susceptibility by inhibition of host programmed cell death. EMBO Journal 22:60-69. 39. Buell, C. R., V. Joardar, M. Lindeberg, J. Selengut, I. T. Paulsen, M. L. Gwinn, R. J. Dodson, R T. Deboy, A. S. Durkin, J F. Kolonay, R. Madupu, S. Daugherty, L. Brinkac, M. J. Beanan, D. H. Haft, W. C. Nelson, T. Davidsen, J. Liu, Q. Yuan, H. Khouri N. Fedorova, B. Tran, D. Russell, K. Berry, T. Utterback, S. E. Vanaken, T. V. Feldblyum, M. D'Ascenzo, W.-L. Deng, A. R. Ramos, J. R. Alfano, S. Cartinhour, A. K. Chatterjee, T. P. Delaney, S. G. Lazarowitz, G. B. Martin, D. J. Schneider, X. Tang, C. L. Bender, O. White, C. M. Fraser and A. R. Collmer (2003). The complete sequence of the Arabidopsis and tomato pathogen Pseudomonas syringae pv tomato DC3000. Proceedings of the National Academy of Sciences USA 100:10181-10186. 40. Chakravarthy, S., R. P. Tuori, M. D. D’Ascenzo, P. R. Fobert, C. Després and G. B. Martin (2003). The tomato transcription factor Pti4 regulates defense-related gene expression via GCC box- and non-GCC box cis elements. Plant Cell 15:3033-3050 41. Ekengren, S. K., M. Schiff, S. P. Dinesh-Kumar, and G. B. Martin (2003). Two MAPK cascades, NPR1, and TGA transcription factors play a role in Pto-mediated disease resistance in tomato. Plant Journal 36:905-917 42. Martin, G. B., A. J. Bogdanove, and G. Sessa (2003). Understanding the functions of plant disease resistance proteins. Annual Review of Plant Biology 54:23-61. 43. Pedley, K. F., and G. B. Martin (2002). Molecular basis of Pto-mediated resistance to bacterial speck disease in tomato. Annual Review of Phytopathology 41:215-43. 44. Fouts, D., R. B. Abramovitch J. R. Alfano, A. M. Baldo, C. R. Buell, S. Cartinhour, A. K. Chatterjee, M. D'Ascenzo, M. L. Gwinn, S. G. Lazarowitz, N.-C. Lin, G. B. Martin, A. H. Rehm, D. J. Schneider, K. van Dijk, X. Tang and A. Collmer (2002). Genome-wide identification of Pseudomonas syringae pv. tomato DC3000 promoters controlled by the HrpL alternative sigma factor. Proceedings of the National Academy of Sciences USA 99:2275-2280. 45. Gu, Y.-G., M. C. Wildermuth, S. Chakravarthy, Y.-T. Loh, C. Yang, X. He, Y. Han and G. B. Martin (2002). Tomato transcription factors Pti4, Pti5, and Pti6 activate defense responses when expressed in Arabidopsis. Plant Cell 14:817-831. 46. Kim, Y.-J., N.-C. Lin and G. B. Martin (2002). Two distinct Pseudomonas effector proteins interact with the Pto kinase and activate plant immunity. Cell 109:589-598.

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47. Riely, B. and G. B. Martin (2001). Ancient origin of pathogen recognition specificity conferred by the tomato disease resistance gene Pto. Proceedings of the National Academy of Sciences USA 98:2059-2064. 48. Gu, Y.-Q., C. Yang, V. K. Thara, J. Zhou and G. B. Martin (2000). The Pti4 gene is regulated by ethylene and salicylic acid and its protein is phosphorylated by the Pto kinase. Plant Cell 12:771-785. 49. Sessa, G., M. D’Ascenzo and G. B. Martin (2000). Thr38 and Ser198 are Pto-autophosphorylation sites required for the AvrPto-Pto mediated hypersensitive response. EMBO Journal 19:2257-2269. 50. Shan, L., V. K. Thara., G. B. Martin, J.-M. Zhou and X. Tang (2000). AvrPto is localized to the plasma membrane and requires two distinct sequences for differential recognition in tomato and tobacco. Plant Cell 12:2323-2337. 51. Tang, X. M. Xie, Y. J. Kim, J. Zhou, D. F. Klessig and G. B. Martin (1999). Overexpression of Pto activates defense responses and confers race-nonspecific resistance. Plant Cell 11:15-29. 52. Jia, Y., Loh, Y.-T., J. Zhou and G. B. Martin (1997). Alleles of Pto and Fen occur in bacterial speck-susceptible and fenthion-insensitive tomato lines and encode functional protein kinases. Plant Cell 9:61-73. 53. Zhou, J., X. Tang and G. B. Martin (1997). The Pto kinase conferring resistance to tomato bacterial speck disease interacts with proteins that bind a cis-element of pathogenesis-related genes. EMBO Journal 16:3207-3218. 54. Tang, X., R. Frederick, D. Halterman, J. Zhou and G. B. Martin (1996). Initiation of plant disease resistance by physical interaction of AvrPto with Pto kinase. Science 274:2060-2063. 55. Tanksley, S. D., M. W. Ganal and G. B. Martin (1995). Chromosome landing: A new paradigm for map-based cloning in species with large genomes. Trends in Genetics 11:63-68 56. Thilmony, R. T., Z. Chen, R. A. Bressan and G. B. Martin (1995). Expression of the tomato Pto gene in tobacco enhances resistance to P. syringae pv. tabaci expressing avrPto. Plant Cell 7:1529-1536. 57. Zhou, J., Y.-T. Loh and G. B. Martin (1995). The Pto kinase conferring resistance to bacterial speck disease in tomato physically interacts with and phosphorylates a second kinase, Pti1. Cell 83:925-935. 58. Martin, G. B., A. Frary, T. Wu, S. Brommonschenkel, J. Chunwongse, E. D. Earle and S. D. Tanksley (1994). A member of the Pto gene family confers sensitivity to fenthion resulting in rapid cell death. Plant Cell, 6:1543-1552. 59. Martin, G. B., S. H. Brommonschenkel , J. Chunwongse, A. Frary, M. W. Ganal, R. Spivey, T. Wu , E. D. Earle and S. D. Tanksley (1993). Map-based cloning of a protein kinase gene conferring disease resistance in tomato. Science 262:1432-1436. 60. Martin, G. B., J. G. Williams and S. D. Tanksley (1991). Rapid identification of markers near a Pseudomonas resistance gene in tomato using random primers and near-isogenic lines. Proceedings of the National Academy of Sciences USA 88:2336-2340.

PUBLICATIONS: Selected Invited Reviews, Book Chapters, Websites, etc.

Angot, A. and G. B. Martin (2009). High School Connect. Pseudomonas-Plant website module for teaching about plant immunity. http://pseudomonas-syringae.org/Outreach/Module_4_Home.htm BTI Nicotiana benthamiana website: http://bti.cornell.edu/research/projects/nicotiana-benthamiana/ Martin, G. B. (2008). Use of tomato as a model system to understand the molecular basis of plant disease resistance. Report of the Tomato Genetics Cooperative 58:6-10. Martin, G. B. (2012). Suppression and activation of the plant immune system by Pseudomonas syringae effectors AvrPto and AvrPtoB. In: Effectors in Plant-Microbe Interactions, Editors: F. Martin and S. Kamoun. Wiley-Blackwell, pp. 123 – 154. NCBI BioProject for N. benthamiana genome sequencing page: www.ncbi.nlm.nih.gov/bioproject?term=PRJNA170566 Velásquez, A. C. and G. B. Martin (2013). Molecular mechanisms involved in the interaction between tomato and Pseudomonas syringae pv. tomato. In: Molecular Plant Immunity, Ed. G. Sessa, Wiley-Blackwell, pp. 187 – 209.

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PATENTS – Pending and Issued

U.S. Provisional Application (62/213,409): “Isolated nucleic acids and quantitative trait loci (QTL) from S. habrochaites and methods of use thereof for increasing resistance to bacterial speck disease in tomato and other plants”. Inventors: G. B. Martin, S. Hind, S. Strickler B. Zhilong. Filed 2015 by the Boyce Thompson Institute, Ithaca, NY. U.S. Provisional Application (61/567,851): “FLGII-28 sensitivity 3 (FLS3) protein and methods of use”. Inventors: G. B. Martin, S. Hind, S. Strickler. Filed 2014 by the Boyce Thompson Institute, Ithaca, NY. Converted to PCT Application No. PCT/US15/39520, filed July 8, 2015. U.S. Provisional Application (62/021,995): “Host proteins engineered to resist interference by pathogen virulence proteins”. Inventor: G. B. Martin. Filed 2012 by the Boyce Thompson Institute, Ithaca, NY. (Not converted to PCT). U.S. Patent No. 7,888,467: “Bacterial effector proteins that inhibit programmed cell death”. Inventor: G. B. Martin and R. B. Abramovitch. Issued February 15, 2011 to the Boyce Thompson Institute, Ithaca, NY. (http://www.google.com/patents/US7888467?dq=7,888,467&ei=ff6STsuJAqbh0QHl_v05) U.S. Provisional Application: “Screening method for the discovery of genes associated with pathogen-associated molecular pattern triggered immunity”. Inventors: G. B. Martin, A. Collmer, A. Velasquez, S. Chakravarthy. Filed December 2009 by the Boyce Thompson Institute, Ithaca, NY (BTI-2009-99). (Not converted to PCT). U.S. Patent No. 7,138,569: “Nucleic acids encoding Pseudomonas Hop proteins and use thereof”. Inventors: A. Collmer, J. R. Alfano, X. Tang, R. C. Buell, and G. B. Martin. Issued November 21, 2006 to Cornell Research Foundation, Boyce Thompson Institute, Kansas State University, The Institute for Genomics Research, and the University of Nebraska. (http://www.google.com/patents/US7138569?dq=patent:7138569) U.S. Patent No. 6,653,533: “Nucleic acids encoding proteins with pathogen resistance activity and plants transformed therewith”. Inventors: G. B. Martin and J.-M. Zhou. Issued November 25, 2003 to Purdue Research Foundation, West Lafayette, IN. (http://www.google.com/patents/US6653533) U.S. Patent No. 5,648,599: “Gene conferring disease resistance to plants by responding to an avirulence gene in plant pathogens”. Inventors: G. B. Martin and S. D. Tanksley. Issued July 15, 1997 to Cornell Research Foundation, Ithaca, NY. (http://www.google.com/patents/US5648599#v=onepage&q&f=false)

INVITED PRESENTATIONS -- SELECTED (since 2007) 1. John and Olga LeTourneau Memorial Seminar, University of Idaho, May 1, 2014 2. Washington State University, April 30, 2014 3. Monsanto, Biotechnology Seminar Series, April 15-17, 2014 4. Texas A&M University, College Station TX, November 6, 2013. 5. University of British Columbia, Vancouver, Canada, October 30, 2013. 6. Lafayette College, Easton, PA, September 25, 2013. 7. King Abdulaziz University, Faculty of Science, Jeddah, Saudi Arabia, February 19, 2013. 8. University of Massachusetts-Amherst, 10th Annual Symposium in Plant Biology: ‘War or Peace? Interactions between plants and microbes’. October 6, 2012 9. New Phytologist meeting on ‘Immunomodulation by plant-associated organisms’. Fallen Leaf Lake, CA. September 16- 19, 2012 10. Noble Foundation, Plant Biology Division. October 27, 2011. 11. Oomycete Molecular Genetics Network Conference. March 13 -15, Asilomar, CA. Keynote Speaker. 12. Keystone Symposium on Receptors and Signaling in Plant Development and Biotic Interactions. March 14 – 19, 2010. Granlibakken Inn, Tahoe City, CA. 13. University of Florida-Gainesville. Plant Cell and Molecular Biology Program (PCMB). March 31, 2010. 14. Ohio State University. Department of Microbiology and the Center for Microbial Interface Biology. April 19, 2010.

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15. 8th International Conference on Pseudomonas syringae at Oxford University. September 1 – 3, 2010. 16. University of Missouri. Daniel F. Milikan Memorial Lecture. October 13, 2010 17. Centro Internacional de la Papa, Lima, Peru. Division of Germplasm Enhancement and Crop Improvement. April 3, 2009. 18. US/Africa Connections conference, sponsored by the Bill and Melinda Gates Foundation. Naivasha, Kenya. June 19- 22, 2009. 19. Biosciences Eastern and Central Africa (BECA) Hub / International Livestock Research Institute (ILRI), Nairobi, Kenya. June 23, 2009. 20. Ethiopian Institute of Agricultural Research. Addis Ababa, Ethiopia. June 29, 2009 21. 22nd New Phytologist Symposium: “Effectors in Plant-Microbe Interactions”. INRA Versailles Research Center, Paris, France. September 13-16, 2009. 22. INRA-Toulouse, Laboratory of Plant-Microbe Interactions, Toulouse, France. September 17, 2009. 23. Michigan State University, DOE Plant Research Laboratory. October 12, 2009. 24. Syracuse University, Department of Biology. October 30, 2009. 25. Keystone meeting on Plant Innate Immunity. Keystone, Colorado. Speaker and Chair of session on type III effectors. February 10 – 14, 2008. 26. University of Wisconsin, Department of Plant Pathology. Madison, WI. April 10, 2008. 27. International symposium of the collaborative research program (SFB) 446: “Mechanisms of Cell Behavior”. Tuebingen, Germany. May 2-3, 2008. 28. University of Munich, Section of Evolutionary Biology. May 5, 2008 29. Max Planck Institute for Molecular Plant Physiology. Golm, Germany. May 7, 2008 30. Tel Aviv University, Department of Plant Sciences. Tel Aviv, Israel. February 13, 2007. 31. Weizmann Institute, Rehovot, Israel. February 15, 2007. 32. Symposium on Plant Innate Immunity. Meiji University, Tokyo, Japan. March 12-13, 2007. 33. RIKEN Yokohama Institute, Plant Sciences Center. Yokohama, Japan. March 14, 2007. 34. Nagoya University, Department of Biological Sciences. Nagoya, Japan. March 15, 2007. 35. Nara Institute of Science and Technology. Nara, Japan. March 16, 2007. 36. Gordon Research Conference on Antimicrobial Peptides. Barga, Italy. May 2, 2007. 37. University of Geneva, Department of Plant Biology, Geneva, Switzerland. May 8, 2007. 38. University of Lausanne, Department of Plant Molecular Biology, Lausanne, Switzerland. May 9, 2007. 39. DFG meeting on: “Molecular mechanisms of information processing in plants”, Martin Luther University. Halle, Germany. May 12, 2007. 40. 13th Congress of the International Society of Molecular Plant-Microbe Interactions. Plenary speaker. Sorrento, Italy. July 24, 2007. 41. Stockholm University, Department of Botany, Stockholm, Sweden. July 27, 2007. 42. University of Maryland – Baltimore County, Department of Biology. Sponsored by the UM ADVANCE Program. Baltimore, Maryland. September 6, 2007. 43. Symposium on Plant-Microbe Interactions, Keynote speaker. National Institute of Biological Sciences (NIBS), Beijing, China. October 8, 2007. 44. Institute of Microbiology and Institute of Genetics and Developmental Biology, Chinese Academy of Sciences. Beijing, China. October 11, 2007.

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CURRENT AND FORMER LAB MEMBERS

GRADUATE STUDENTS (*Current, Total of 15)

Name University Degree Year Current Position *Christine Kraus Cornell University *Simon Schwizer Cornell University Andre Velasquez Cornell University Ph.D. 2012 Postdoc, Michigan State University Hanh Nguyen Cornell University Ph.D. 2010 Consultant, McKinsey & Company Tracy Rosebrock Cornell University Ph.D. 2007 Research Scientist, Harvard University Robert Abramovitch Cornell University Ph.D. 2006 Assistant Professor, Michigan State University Pete Pascuzzi Cornell University Ph.D. 2006 Assistant Professor, Purdue University Jeffrey Anderson Cornell University Ph.D. 2005 Assistant Professor, Oregon State University Nai-Chun Lin Cornell University Ph.D. 2004 Associate Professor, National Taiwan University Anjali Iyer Cornell University M.S. 2001 Assistant Professor, Purdue University Brendan Riely Purdue University Ph.D. 2001 Research Scientist, U. California-Davis Dennis Halterman Purdue University Ph.D. 1999 Scientist, USDA-ARD, Madison, WI Roger Thilmony Purdue University Ph.D. 1998 Scientist, USDA-PGEC, Albany, CA Ying-Ysu Loh Purdue University Ph.D. 1998 Associate Professor, San Francisco City College Yulin Jia Purdue University Ph.D. 1997 Scientist, USDA-ARS, Stuttgart, AR

POSTDOCTORAL ASSOCIATES (*Current, Total of 38)

Name Current Position Institution / Company *Dr. Thomas Jacobs (2014 – Present) *Dr. Sarah Hind (2011 – Present) Dr. Jay Worley Postdoctoral Associate U. Maryland Dr. Zhilong Bao Research Associate U. Florida Dr. Fanhong Meng Research Associate Texas A&M University, TX Dr. Marina Pombo Scientist IIB-INTECH, Buenos Aires, Argentina Dr. Hernan Rosli Scientist IIB-INTECH, Buenos Aires, Argentina Dr. In Sun Hwang Research Associate Korea University Dr. Patrick Boyle Emerging Leader Program Monsanto, MO Dr. Johannes Mathieu Scientist Agri-Neo, Toronto, CANADA Dr. Chang-Sik Oh Assistant Professor Kyung-Hee University, Seoul, KOREA Dr. Kathy Munkvold Scientist Genomics Group, Beckman Coulter, IN Dr. Jesse Munkvold Bioinformaticist Dow Agro Sciences, IN Dr. Lirong Zeng Assistant Professor University of Nebraska, NE Dr. Inhwa Yeam Assistant Professor Andong National University, KOREA Dr. Suma Chakravarthy Research Associate Cornell University, NY Dr. Aurelie Angot Science journalist Normandy, FRANCE Dr. Fangming Xiao Associate Professor University of Idaho, Boise, ID Dr. Tim Devarenne Associate Professor Texas A & M University, College Station, TX Dr. Patrick Giavalisco Project Leader Max Planck Institute – Golm, GERMANY Dr. Kerry Pedley Scientist USDA Foreign Disease Unit-Fort Detrick, MD Dr. Jonathan Cohn Research Scientist Syngenta Biotechnology, Inc., Raleigh, NC Dr. Olga del Pozo Associate Professor Universidad de Seville, SPAIN Dr. Sophia Ekengren Associate Professor Stockholm University, SWEDEN Dr. Adriana Ferreira Research Associate Virginia Bioinformatics Institute, Blacksburg, VA Dr. Nai-Chun Lin Associate Professor National Taiwan University, TAIWAN Dr. Kiran Mysore Professor Noble Foundation, Ardmore, OK Dr. Ramesh Kantety Associate Professor Alabama A&M University, AL

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Dr. Hitoshi Nakayashiki Associate Professor Kobe University, JAPAN Dr. Adam Bogdanove Professor Cornell University, NY Dr. Yong Gu Scientist USDA/ARS, Albany, CA Dr. Xiaohua He Scientist USDA/ARS, Albany, CA Dr. Robert Tuori Biology/Chemistry Teacher Ithaca High School, Ithaca, NY Dr. Young Jin Kim Associate Professor Korea University, Seoul, KOREA Dr. Guido Sessa Associate Professor Tel Aviv University, ISRAEL Dr. Reid Frederick Scientist USDA Foreign Disease Unit-Fort Detrick, MD Dr. Xiaoyan Tang Deputy Director Shenzhen Institute of Molecular Crop Design, CHINA Dr. Jian-Min Zhou Professor Chinese National Academy of Science, CHINA

SELECTED INTERNAL ACTIVITIES – BOYCE THOMPSON INSTITUTE and CORNELL UNIVERSITY

BOYCE THOMPSON INSTITUTE (BTI) – Past 5 years

• Acting President, July – December, 2014 • Chair, Plant Growth Facilities Oversight Committee, 2010 – Present • Faculty-elected liaison to the BTI Senior Leadership Team, 2014 • Member, Faculty Advisory Committee to the BTI President, 2005 – 2015 • Member, Peer Evaluation Committee (PEC). Faculty-elected member, 2011 – 2013 • Member, Ad Hoc committee to evaluate post-tenure review and tenure, 2012 – 2013 • Organized and hosted visit from faculty of King Abdulaziz University, Jeddah, Saudi Arabia, March 2013 • BTI Intellectual Property Ad Hoc Review Committee, 2011 • Chair, BTI Search Committee for Faculty Member in Plant Biotic Interactions, 2011 – 2012

CORNELL UNIVERITY – Past 5 years • Participant, Cornell University Leadership Course, January 2011 • Member, Cornell University Graduate Field of Plant Pathology & Plant-Microbe Biology, 1998 – Present • Member, Cornell University Graduate Field of Plant Biology, 1998 – Present • Organized and led a Field Day for the NSF Summer Interns (2007, 2008, 2011).

SELECTED PROFESSIONAL ACTIVITIES – EXTERNAL • Member, American Society of Microbiology • Member, American Society of Plant Biology • Member, American Phytopathological Society • Member, International Society of Molecular Plant-Microbe Interactions • Member, American Association for the Advancement of Science • Elected Member, AAAS Electorate Nominating Committee; Section on Agriculture, Food and Renewable Resources • Member, College of Reviewers for the Canada Research Chairs Program. 2011 – Present • Consultant, Genomics and Biotechnology Section, Department of Biological Sciences, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia. 2011 – 2015 • Chair, Session on Plant Responses. 8th International Conference on Pseudomonas syringae at Oxford University. September 1-3, 2010 • Visiting Scientist, Gulf Coast Research and Education Center, Wimauma, FL, December 1, 2008 – May 1, 2009 • Eminent Scholar Mentor. Serve as an ADVANCE program participant in support of junior female faculty members Supported by an NSF Institutional Transformation Award. (http://www.umbc.edu/advance), 2007 – 2012 • Participated as one of 20 US participants in the Africa/US Connections conference, sponsored by the Bill and Melinda Gates Foundation. Naivasha, Kenya. June 19-22, 2009.

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INTERACTIONS WITH THE MEDIA • Recent BTI Stories / Press releases:

• Scientists find new tool for pathogen to pillage plants. By Patricia Waldron, June 17, 2015. (http://bti.cornell.edu/news/scientists-find-new-tool-for-pathogen-to-pillage-plants/)

• New website is portal for Nicotiana benthamiana experimental resources. By Chris White, January 13, 2014. (http://bti.cornell.edu/news/new-website-serves-as-a-portal-for-nicotiana-benthamiana-experimental-resources-2/)

• A wild relative of tobacco offers insight into molecular plant biology at BTI, May 12, 2013. (http://bti.cornell.edu/news/a-wild-relative-of-tobacco-offers-insight-into-molecular-plant-biology-at-bti/) • Research was highlighted in the Cornell Chronicle Online: “Researchers discover how pathogen causes speck disease in tomatoes”. December 14, 2011 • Research was highlighted in the Cornell Chronicle: “Cornell receives $500,000 to tackle Salmonella in tomatoes”. June 27, 2011. • Interviewed by Bill Jaker as background for a subsequent radio program on WSKG. July 14, 2011. • Research was highlighted in the Cornell Chronicle: “$4M grant to explore plant-pathogen ‘cat and mouse’ games”. March 24, 2011. • Research was highlighted in Cornell’s 2007 Annual Report from the Office of the Vice Provost for Research: “Pathogens versus plans defense: An ancient evolutionary battle”. p. 10 • Cornell Chronicle. Interviewed for article by Krishna Ramanujan: “In evolutionary arms race, a bacterium is found that outwits tomato plant's defenses, Cornell study finds”. July 18, 2007. • MicrobeWorld Radio, Interviewed for program about how bacteria infect plants. Broadcast September 13, 2005. • Cornell Chronicle. Interviewed for article: “Five CU researchers named fellows of world’s largest scientific group”. November 4, 2004 • Associated Press. Interviewed by Emily Gersema for story about sequencing of the Pseudomonas syringae DC3000 genome. Story ran on the AP national wire, broadcast wire, and the AP Worldstream. August 18, 2003. • Cornell Chronicle: Genome sequencing of leading pathogen offers hope for disease defenses. August 28, 2003. • Cornell News Service: “Pseudomonas syringae genome sequenced”. News release August 18, 2003.

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