The Impact of Hypermobility Spectrum Disorders on Musculoskeletal Tissue Stiffness: an Exploration Using Strain Elastography
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Association of Generalized Joint Hypermobility and the Occurrence of Musculoskeletal Work-Related Injury in the First Zero to Fi
University of North Dakota UND Scholarly Commons Physical Therapy Scholarly Projects Department of Physical Therapy 2018 Association of Generalized Joint Hypermobility and the Occurrence of Musculoskeletal Work- Related Injury in the First Zero to Five Years of Physical Therapy Practice: A Pilot Study Mikelle Fetsch University of North Dakota Ashley Naas University of North Dakota Amanda Slaikeu University of North Dakota Follow this and additional works at: https://commons.und.edu/pt-grad Part of the Physical Therapy Commons Recommended Citation Fetsch, Mikelle; Naas, Ashley; and Slaikeu, Amanda, "Association of Generalized Joint Hypermobility and the Occurrence of Musculoskeletal Work-Related Injury in the First Zero to Five Years of Physical Therapy Practice: A Pilot Study" (2018). Physical Therapy Scholarly Projects. 655. https://commons.und.edu/pt-grad/655 This Scholarly Project is brought to you for free and open access by the Department of Physical Therapy at UND Scholarly Commons. It has been accepted for inclusion in Physical Therapy Scholarly Projects by an authorized administrator of UND Scholarly Commons. For more information, please contact [email protected]. ASSOCIATION OF GENERALIZED JOINT HYPERMOBlLlTY AND THE OCCURRENCE OF MUSCULOSKELETAL WORK-RELATED INJURY IN THE FIRST ZERO TO FIVE YEARS OF PHYSICAL THERAPY PRACTICE: A PILOT STUDY by Mikelle Fetsch Bachelor of General Stndies with a Health Sciences Emphasis University of North Dakota, 2016 Ashley Naas Bachelor of General Studies with a Health Sciences Emphasis -
Myositis Center Myositis Center
About The Johns Hopkins The Johns Hopkins Myositis Center Myositis Center he Johns Hopkins Myositis Center, one Tof the first multidisciplinary centers of its kind that focuses on the diagnosis and management of myositis, combines the ex - pertise of rheumatologists, neurologists and pulmonologists who are committed to the treatment of this rare disease. The Center is conveniently located at Johns Hopkins Bayview Medical Center in Baltimore, Maryland. Patients referred to the Myositis Center can expect: • Multidisciplinary Care: Johns Hopkins Myositis Center specialists make a diagno - sis after evaluating each patient and re - viewing results of tests that include muscle enzyme levels, electromyography, muscle biopsy, pulmonary function and MRI. The Center brings together not only physicians with extensive experience in di - agnosing, researching and treating myosi - tis, but nutritionists and physical and occupational therapists as well. • Convenience: Same-day testing and appointments with multiple specialists are The Johns Hopkins typically scheduled to minimize doctor Myositis Center visits and avoid delays in diagnosis and Johns Hopkins Bayview Medical Center treatment. Mason F. Lord Building, Center Tower 5200 Eastern Avenue, Suite 4500 • Community: Because myositis is so rare, Baltimore, MD 21224 the Center provides a much-needed oppor - tunity for patients to meet other myositis patients, learn more about the disease and Physician and Patient Referrals: 410-550-6962 be continually updated on breakthroughs Fax: 410-550-3542 regarding treatment options. www.hopkinsmedicine.org/myositis The Johns Hopkins Myositis Center THE CENTER BRINGS TOGETHER Team NOT ONLY PHYSICIANS WITH EXTENSIVE EXPERIENCE IN DIAGNOSING , RESEARCHING AND Lisa Christophe r-Stine, TREATING MYOSITIS , BUT M.D., M.P.H. -
The Ehlers–Danlos Syndromes
PRIMER The Ehlers–Danlos syndromes Fransiska Malfait1 ✉ , Marco Castori2, Clair A. Francomano3, Cecilia Giunta4, Tomoki Kosho5 and Peter H. Byers6 Abstract | The Ehlers–Danlos syndromes (EDS) are a heterogeneous group of hereditary disorders of connective tissue, with common features including joint hypermobility, soft and hyperextensible skin, abnormal wound healing and easy bruising. Fourteen different types of EDS are recognized, of which the molecular cause is known for 13 types. These types are caused by variants in 20 different genes, the majority of which encode the fibrillar collagen types I, III and V, modifying or processing enzymes for those proteins, and enzymes that can modify glycosaminoglycan chains of proteoglycans. For the hypermobile type of EDS, the molecular underpinnings remain unknown. As connective tissue is ubiquitously distributed throughout the body, manifestations of the different types of EDS are present, to varying degrees, in virtually every organ system. This can make these disorders particularly challenging to diagnose and manage. Management consists of a care team responsible for surveillance of major and organ-specific complications (for example, arterial aneurysm and dissection), integrated physical medicine and rehabilitation. No specific medical or genetic therapies are available for any type of EDS. The Ehlers–Danlos syndromes (EDS) comprise a genet six EDS types, denominated by a descriptive name6. The ically heterogeneous group of heritable conditions that most recent classification, the revised EDS classification in share several clinical features, such as soft and hyper 2017 (Table 1) identified 13 distinct clinical EDS types that extensible skin, abnormal wound healing, easy bruising are caused by alterations in 19 genes7. -
Focal Eosinophilic Myositis Presenting with Leg Pain and Tenderness
CASE REPORT Ann Clin Neurophysiol 2020;22(2):125-128 https://doi.org/10.14253/acn.2020.22.2.125 ANNALS OF CLINICAL NEUROPHYSIOLOGY Focal eosinophilic myositis presenting with leg pain and tenderness Jin-Hong Shin1,2, Dae-Seong Kim1,2 1Department of Neurology, Research Institute for Convergence of Biomedical Research, Pusan National University Yangsan Hospital, Yangsan, Korea 2Department of Neurology, Pusan National University School of Medicine, Yangsan, Korea Focal eosinophilic myositis (FEM) is the most limited form of eosinophilic myositis that com- Received: September 11, 2020 monly affects the muscles of the lower leg without systemic manifestations. We report a Revised: September 29, 2020 patient with FEM who was studied by magnetic resonance imaging and muscle biopsy with Accepted: September 29, 2020 a review of the literature. Key words: Myositis; Eosinophils; Magnetic resonance imaging Correspondence to Dae-Seong Kim Eosinophilic myositis (EM) is defined as a group of idiopathic inflammatory myopathies Department of Neurology, Pusan National associated with peripheral and/or intramuscular eosinophilia.1 Focal eosinophilic myositis Univeristy School of Medicine, 20 Geu- mo-ro, Mulgeum-eup, Yangsan 50612, (FEM) is the most limited form of EM and is considered a benign disorder without systemic 2 Korea manifestations. Here, we report a patient with localized leg pain and tenderness who was Tel: +82-55-360-2450 diagnosed as FEM based on laboratory findings, magnetic resonance imaging (MRI), and Fax: +82-55-360-2152 muscle biopsy. E-mail: [email protected] ORCID CASE Jin-Hong Shin https://orcid.org/0000-0002-5174-286X A 26-year-old otherwise healthy man visited our outpatient clinic with leg pain for Dae-Seong Kim 3 months. -
Joint Hypermobility in Adults Referred to Rheumatology Clinics
Annals ofthe Rheumatic Diseases 1992; 51: 793-796 793 Joint hypermobility in adults referred to Ann Rheum Dis: first published as 10.1136/ard.51.6.793 on 1 June 1992. Downloaded from rheumatology clinics Alan J Bridges, Elaine Smith, John Reid Abstract rheumatologist for musculoskeletal problems, Joint hypermobility is a rarely recognised we evaluated 130 consecutive new patients for aetiology for focal or diffuse musculoskeletal joint hypermobility and associated clinical symptoms. To assess the occurrence and features. importance of joint hypermobility in adult patients referred to a rheumatologist, we prospectively evaluated 130 consecutive Patients and methods new patients for joint hypermobility. Twenty PATIENTS women (15%) had joint hypermobility at One hundred and thirty consecutive adult three or more locations (¢5 points on a patients (age >18 years) referred to the out- 9 point scale). Most patients with joint patient rheumatology clinic at the University hypermobility had common musculoskeletal of Missouri-Columbia for musculoskeletal problems as the reason for referral. Two problems or connective tissue disease were patients referredwith adiagnosis ofrheumatoid evaluated by ES and AJB. There were 97 arthritis were correctly reassigned a diagnosis women and 33 men with an average age of 51 of hypermobility syndrome. Three patients years (range 18-83). with systemic lupus erythematosus had diffuse joint hypermobility. There was a statistically significant association between METHODS diffuse joint hypermobility and osteoarthritis. A complete history and physical examination Most patients (65%) had first degree family was performed including an examination for members with a history of joint hypermobility. joint laxity. The criteria devised by Carter and These results show that joint hypermobility is Wilkinson'5 with a modification by Beighton common, familial, found in association with et al 8 were used to assess hypermobility (table common rheumatic disorders, and statistically 1). -
Hypermobility Spectrum Disorder (HSD)
Hypermobility Spectrum Disorder (HSD) Dr Alan Hakim MA FRCP Consultant Rheumatologist & Acute Physician Clinical Lead, Hypermobility Unit, The Wellington Hospital, London UK For The Ehlers-Danlos Society: Director of Education Member, Medical & Scientific Board Member, Steering Committee, The Internal Collaborative on EDS Member, PCORI EDS Co-morbidity Coalition Content • Bridging the gap between hypermobility in the well population, and hEDS • A spectrum of illness rather than a single definition – Regional vs general hypermobility – Associations / co-morbidities • Clinical Practical 3 For colleagues not familiar with the 2017 classification and terminology, the Joint Hypermobility Syndrome (JHS) diagnostic criteria covered a wide group of patients some of whom had signs and symptoms that might equally be described as the Hypermobile variant of Ehlers-Danlos syndrome (EDS-HM). As such some confusion arose over the use of JHS/EDS-HM co-terminology. 4 The 2017 international criteria for the Hypermobile variant of EDS (hEDS) were developed to address this, give clarity as to the diagnosis of hEDS, and also allow opportunity for more focused basic science and clinical research including assessment of treatment outcomes. 5 The term JHS has been dropped. Those individuals with hypermobility-related problems that do not have hEDS; or any other Heritable Disorder of Connective Tissue; or other syndromic or secondary myopathic, neuropathic, or traumatic cause for hypermobility / joint instability are now given the diagnosis of Hypermobility Spectrum Disorder (HSD). 6 There is a ‘spectrum’ of presentations laying between asymptomatic hypermobility and the diagnosis of hEDS. This does not infer any greater severity at one end of the spectrum compared to the other. -
Hypermobility Syndrome
EDS and TOMORROW • NO financial disclosures • Currently at Cincinnati Children’s Hospital • As of 9/1/12, will be at Lutheran General Hospital in Chicago • Also serve on the Board of Directors of the Ehlers-Danlos National Foundation (all Directors are volunteers) • Ehlers-Danlos syndrome(s) • A group of inherited (genetic) disorders of connective tissue • Named after Edvard Ehlers of Denmark and Henri- Alexandre Danlos of France Villefranche 1997 Berlin 1988 Classical Type Gravis (Type I) Mitis (Type II) Hypermobile Type Hypermobile (Type III) Vascular Type Arterial-ecchymotic (Type IV) Kyphoscoliosis Type Ocular-Scoliotic (Type VI) Arthrochalasia Type Arthrochalasia (Type VIIA, B) Dermatosporaxis Type Dermatosporaxis (Type VIIC ) 2012? • X-Linked EDS (EDS Type V) • Periodontitis type (EDS Type VIII) • Familial Hypermobility Syndrome (EDS Type XI) • Benign Joint Hypermobility Syndrome • Hypermobility Syndrome • Progeroid EDS • Marfanoid habitus with joint laxity • Unspecified Forms • Brittle cornea syndrome • PRDM5 • ZNF469 • Spondylocheiro dysplastic • Musculocontractural/adducted thumb clubfoot/Kosho • D4ST1 deficient EDS • Tenascin-X deficiency EDS Type Genetic Defect Inheritance Classical Type V collagen (60%) Dominant Other? Hypermobile Largely unknown Dominant Vascular Type III collagen Dominant Kyphoscoliosis Lysyl hydroxylase (PLOD1) Recessive Arthrochalasia Type I collagen Dominant Dermatosporaxis ADAMTS2 Recessive Joint Hypermobility 1. Passive dorsiflexion of 5th digit to or beyond 90° 2. Passive flexion of thumbs to the forearm 3. Hyperextension of the elbows beyond 10° 1. >10° in females 2. >0° in males 4. Hyperextension of the knees beyond 10° 1. Some knee laxity is normal 2. Sometimes difficult to understand posture- forward flexion of the hips usually helps 5. Forward flexion of the trunk with knees fully extended, palms resting on floor 1. -
5 Common Causes of Shoulder Pain
5 Common Causes of Shoulder Pain Leslie B. Vidal, M.D. Orthopedic Associates, LLC 303-321-6600 Rotator Cuff Syndrome: Inflammation of rotator cuff tendons and subacromial bursitis, can proceed rotator cuff tear. History: Insidious onset of anterior and lateral shoulder pain, worse with reaching overhead and behind (putting dishes away in upper cabinet, reaching into the back seat of car). Patients often report positional night pain. Symptoms may be partially alleviated with NSAIDs and ice. Exam: Pain at the extremes of shoulder range of motion, no significant loss of motion. Strength is intact although may be slightly guarded due to pain. Impingement tests positive. Treatment: NSAIDs, Physical Therapy for scapular stabilizing exercises and rotator cuff strengthening. When to refer: If no improvement with 6 weeks of NSAIDs and PT, consider MRI to rule out rotator cuff tear. Consider referral to shoulder surgeon for ultrasound guided subacromial cortisone injection. Surgery can be considered for refractory cases. If there is significant loss of motion (see adhesive capsulitis) or weakness (may have rotator cuff tear), consider immediate referral as NSAIDs and PT may not be as effective in these cases. A history of trauma resulting in shoulder weakness should lead to a prompt referral to a shoulder surgeon, as this may represent an acute RCT. Instability: Subluxation or dislocation of the glenohumeral joint. Can be acute and traumatic and unidirectional; or recurrent, atraumatic and multidirectional. History: Patient may report a traumatic injury to the shoulder resulting in a dislocation requiring a reduction maneuver; or a more nonspecific history of shoulder pain and sense of instability that the patient is able to self-reduce. -
The Correlation Between Hypermobility Syndrome and the Incidence of Musculoskeletal Injuries in Male Club Rugby Players
The Correlation Between Hypermobility Syndrome and the Incidence of Musculoskeletal Injuries in Male Club Rugby Players Joseph Ryan Bautista, DO, Jeremy Hanson, DO, Clifford Stark, DO Primary Care Sports Medicine Fellowship Northwell Health at Plainview Hospital Introduction ■ Hypermobility is a risk factor for musculoskeletal injury ■ Numerous research has been conducted, primarily on Ehlers- Danlos Syndrome (EDS) patients, with little research done on non- EDS patients ■ The purpose of this study is to determine if any correlation exists between hypermobility and musculoskeletal injuries, with male club rugby players serving as the subjects of this study ■ Our hypothesis is that there is a positive correlation between the level of hypermobility and the incidence of musculoskeletal injuries sustained by male club rugby players Methods / Study Design ■ Northwell IRB exemption was obtained ■ Single center retrospective analysis ■ 55 male club rugby players were screened for hypermobility via Beighton scores at their pre-participation physical evaluations prior to the Fall 2019 season – Inclusion criteria: players active for at least 80% of games (N=50) – Exclusion criteria: players inactive for greater than 20% of games (Not as a result of MSK injury, N=5) N = 55 total rugby players Met Inclusion Excluded: Criteria: N = 5 N = 50 Figure 1: Number of players meeting inclusion / exclusion criteria ■ All in-season musculoskeletal injuries sustained were recorded by their training staff Figure 2: The Beighton Score scoring system Results ■ N = 50 ■ All male subjects ■ Mean age of 27.31 years old ■ Age range of 19-34 years old ■ Ethnic Backgrounds – 52% Caucasian – 24% African American – 16% Hispanic – 8% Asian / Pacific Islander ■ Sept. -
Association of Generalized Joint Hypermobility and Occurrence of Musculoskeletal Injury in Physical and Occupational Therapy
University of North Dakota UND Scholarly Commons Physical Therapy Scholarly Projects Department of Physical Therapy 2015 Association of Generalized Joint Hypermobility and Occurrence of Musculoskeletal Injury in Physical and Occupational Therapy Students Patricia Bisek University of North Dakota Hannah Owen University of North Dakota Maleeka Rozeboom University of North Dakota Leah Tunseth University of North Dakota Follow this and additional works at: https://commons.und.edu/pt-grad Part of the Physical Therapy Commons Recommended Citation Bisek, Patricia; Owen, Hannah; Rozeboom, Maleeka; and Tunseth, Leah, "Association of Generalized Joint Hypermobility and Occurrence of Musculoskeletal Injury in Physical and Occupational Therapy Students" (2015). Physical Therapy Scholarly Projects. 606. https://commons.und.edu/pt-grad/606 This Scholarly Project is brought to you for free and open access by the Department of Physical Therapy at UND Scholarly Commons. It has been accepted for inclusion in Physical Therapy Scholarly Projects by an authorized administrator of UND Scholarly Commons. For more information, please contact [email protected]. ASSOCIATION OF GENERALIZED JOINT HYPERMOBILITY AND OCCURRENCE OF MUSCULOSKELETAL INJURY IN PHYSICAL AND OCCUPATIONAL THERAPY STUDENTS by Patricia Bisek Bachelor of Arts in Exercise Science Concordia College, 2012 Hannah Owen Bachelor of Arts in Biology with Emphasis in Health and Medical Sciences Minnesota State University Moorhead, 2011 Maleeka Rozeboom Leah Tunseth A Scholarly Project Submitted -
“I Think I May Have EDS” (Ehlers Danlos Syndrome)
“I think I may have EDS” (Ehlers Danlos Syndrome) If you think you may have Ehlers Danlos Syndrome (EDS), you have a predicament: hardly any doctors know how to diagnose it, let alone treat it. This article aims to help you with information and strategies to help with that predicament, and get better medical care. The EDS predicament Many people think they have EDS – or rather, one of them, since there are several Ehlers Danlos Syndromes. Some of these people have medical problems that resemble those of a relative who has been diagnosed with an EDS, so they wonder if they have one too. Or, they’ve been surfing the web to learn more about some ailment, and they find it can be part of an EDS, and then they read more, and it all seems to fit them. Or, they see a doctor who notices they have some loose joints and wonders aloud about EDS. If you ask, say, an orthopedist or a rheumatologist whether you have an EDS, and if so what to do about it, you are likely to get a version of one of the following responses: “It’s just a name, don’t worry about it.” “It’s inherited, so there’s nothing you can do about it.” “See a geneticist.” “It’s probably fibromyalgia.” “Have you thought of getting counseling?” None of these is helpful, if you are hurting and tired all the time, and getting worse, with an assortment of other symptoms that your doctors discount, or perhaps hint may be all in your mind. -
Scleroderma, Myositis and Related Syndromes [4] Giordano J, Khung S, Duhamel A, Hossein-Foucher C, Bellèvre D, Lam- Blin N, Et Al
Scientific Abstracts 1229 Ann Rheum Dis: first published as 10.1136/annrheumdis-2021-eular.75 on 19 May 2021. Downloaded from Scleroderma, myositis and related syndromes [4] Giordano J, Khung S, Duhamel A, Hossein-Foucher C, Bellèvre D, Lam- blin N, et al. Lung perfusion characteristics in pulmonary arterial hyper- tension and peripheral forms of chronic thromboembolic pulmonary AB0401 CAN DUAL-ENERGY CT LUNG PERFUSION hypertension: Dual-energy CT experience in 31 patients. Eur Radiol. 2017 DETECT ABNORMALITIES AT THE LEVEL OF LUNG Apr;27(4):1631–9. CIRCULATION IN SYSTEMIC SCLEROSIS (SSC)? Disclosure of Interests: None declared PRELIMINARY EXPERIENCE IN 101 PATIENTS DOI: 10.1136/annrheumdis-2021-eular.69 V. Koether1,2, A. Dupont3, J. Labreuche4, P. Felloni3, T. Perez3, P. Degroote5, E. Hachulla1,2,6, J. Remy3, M. Remy-Jardin3, D. Launay1,2,6. 1Lille, CHU Lille, AB0402 SELF-ASSESSMENT OF SCLERODERMA SKIN Service de Médecine Interne et Immunologie Clinique, Centre de référence THICKNESS: DEVELOPMENT AND VALIDATION OF des maladies autoimmunes systémiques rares du Nord et Nord-Ouest de THE PASTUL QUESTIONNAIRE 2 France (CeRAINO), Lille, France; Lille, Université de Lille, U1286 - INFINITE 1,2 1 1 1 J. Spierings , V. Ong , C. Denton . Royal Free and University College - Institute for Translational Research in Inflammation, Lille, France; 3Lille, Medical School, University College London, Division of Medicine, Department From the Department of Thoracic Imaging, Hôpital Calmette, Lille, France; 4 of Inflammation, Centre for Rheumatology and Connective