Collagen-Based Matrix Matrix Auf Der Basis Von Kollagen Matrice À Base De Collagène
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Uvic Thesis Template
Insight into the Functionality of an Unusual Glycoside Hydrolase from Family 50 by Kaleigh Giles BSc, Brock University, 2011 A Thesis Submitted in Partial Fulfillment of the Requirements for the Degree of MASTER OF SCIENCE in the Department of Biochemistry and Microbiology Kaleigh Giles, 2014 University of Victoria All rights reserved. This thesis may not be reproduced in whole or in part, by photocopy or other means, without the permission of the author. ii Supervisory Committee Insight into the Functionality of an Unusual Glycoside Hydrolase from Family 50 by Kaleigh Giles BSc, Brock University, 2011 Supervisory Committee Dr. Alisdair B. Boraston, Department of Biochemistry and Microbiology Supervisor Dr. Martin J. Boulanger (Department of Biochemistry and Microbiology) Departmental Member Dr. Fraser Hof (Department of Chemistry) Outside Member iii Abstract Supervisory Committee Dr. Alisdair B. Boraston, Department of Biochemistry and Microbiology Supervisor Dr. Martin J. Boulanger, Department of Biochemistry and Microbiology Departmental Member Dr. Fraser Hof, Department of Chemistry O utside Member Agarose and porphyran are related galactans that are only found within red marine algae. As such, marine microorganisms have adapted to using these polysaccharides as carbon sources through the acquisition of unique Carbohydrate Active enZymes (CAZymes). A recent metagenome study of the microbiomes from a Japanese human population identified putative CAZymes in several bacterial species, including Bacteroides plebeius that have significant amino acid sequence similarity with those from marine bacteria. Analysis of one potential CAZyme from B. plebeius (BpGH50) is described here. While displaying up to 30% sequence identity with β-agarases, BpGH50 has no detectable agarase activity. Its crystal structure reveals that the topology of the active site is much different than previously characterized agarases, while containing the same core catalytic machinery. -
United States Patent Office
- 2,926,180 United States Patent Office Patented Feb. 23, 1960 2 cycloalkyl, etc. These substituents R and R' may also be substituted with various groupings such as carboxyl 2,926,180 groups, sulfo groups, halogen atoms, etc. Examples of CONDENSATION OF AROMATIC KETONES WITH compounds which are included within the scope of this CARBOHYDRATES AND RELATED MATER ALS 5 general formula are acetophenone, propiophenone, benzo Carl B. Linn, Riverside, Ill., assignor, by mesne assign phenone, acetomesitylene, phenylglyoxal, benzylaceto ments, to Universal Oil Products Company, Des phenone, dypnone, dibenzoylmethane, benzopinacolone, Plaines, Ill., a corporation of Delaware dimethylaminobenzophenone, acetonaphthalene, benzoyl No Drawing. Application June 18, 1957 naphthalene, acetonaphthacene, benzoylnaphthacene, ben 10 zil, benzilacetophenone, ortho-hydroxyacetophenone, para Serial No. 666,489 hydroxyacetophenone, ortho - hydroxy-para - methoxy 5 Claims. (C. 260-345.9) acetophenone, para-hydroxy-meta-methoxyacetophenone, zingerone, etc. This application is a continuation-in-part of my co Carbohydrates which are condensed with aromatic pending application Serial No. 401,068, filed December 5 ketones to form a compound selected from the group 29, 1953, now Patent No. 2,798,079. consisting of an acylaryl-desoxy-alditol and an acylaryl This invention relates to a process for interacting aro desoxy-ketitol include simple sugars, their desoxy- and matic ketones with carbohydrates and materials closely omega-carboxy derivatives, compound sugars or oligo related to carbohydrates. The process relates more par saccharides, and polysaccharides. ticularly to the condensation of simple sugars, their 20 Simple sugars include dioses, trioses, tetroses, pentoses, desoxy- and their omega-carboxy derivatives, compound hexoses, heptoses, octoses, nonoses, and decoses. Com sugars or oligosaccharides, and polysaccharides with aro pound sugars include disaccharides, trisaccharides, and matic ketones in the presence of a hydrogen fluoride tetrasaccharides. -
Proquest Dissertations
Feeding and oviposition behavior of tobacco hornworms, Manduca sexta, in relation to Myo-inositol Item Type text; Thesis-Reproduction (electronic) Authors Nelson, Nancy Marie, 1968- Publisher The University of Arizona. Rights Copyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author. Download date 07/10/2021 15:39:03 Link to Item http://hdl.handle.net/10150/278543 INFORMATION TO USERS This manuscript has been reproduced from the microfilm master. UMI films the text directly from the original or copy submitted. Thus, some thesis and dissertation copies are in typewriter face, while others may be from any type of computer printer. The quality of this reproduction is dependent upon the quality of the copy submitted. Broken or indistinct print, colored or poor quality illustrations and photographs, print bleedthrough, substandard margins, and improper alignment can adversely affect reproduction. In the unlikely event that the author did not send UMI a complete manuscript and there are missing pages, these will be noted. Also, if unauthorized copyright material had to be removed, a note will indicate the deletion. Oversize materials (e.g., maps, drawings, charts) are reproduced by sectioning the original, beginning at the upper left-hand comer and continuing from left to right in equal sections with small overlaps. Each original is also photographed in one exposure and is included in reduced form at the back of the book. -
Glycoconjugates
Background Information on Glycoconjugates Richard D. Cummings, Ph.D. Director, National Center for Functional Glycomics Professor Department of Surgery Beth Israel Deaconess Medical Center Harvard Medical School Boston, MA 02114 Tel: (617) 735-4643 e-mail: [email protected] For General Reference On-Line See: Essentials of Glycobiology (2nd Edition) Varki, Cummings, Esko, Freeze, Stanley, Bertozzi, Hart and Etzler) http://www.ncbi.nlm.nih.gov/books/NBK1908/ Mammalian Cells are Covered with Glycoconjugates GLYCOSAMINOGLYCANS/ GLYCOPROTEINS PROTEOGLYCANS GLYCOLIPIDS NUCLEAR/CYTOPLASMIC GLYCOPROTEINS 2 Mammalian Glycoconjugates are Recognized by a Wide Variety of Specific Proteins GLYCAN-BINDING PROTEIN (GBP) GBP ANTIBODY TOXIN GBP GBP VIRUS 7 ANTIBODY GBP MICROBE TOXIN 3 Glycosylation Pathways 4 Glycosylation Pathways 5 Glycoconjugates, Which are Molecules Containing Sugars (Monosaccharides) Linked Within Them, are the Major Constituents of Animal Cell Membranes (Glycocalyx) and Secreted Material: See Different Classes of Glycoconjugates Below in Red Boxes PROTEOGLYCANS GLYCOSAMINOGLYCANS GLYCOSAMINOGLYCANS GLYCOPROTEINS GPI-ANCHORED GLYCOPROTEINS GLYCOLIPIDS outside Cell Membrane cytoplasm Essentials of Glycobiology, 3rd Edition CYTOPLASMIC GLYCOPROTEINS Chapter 1, Figure 6 Glycans are as Ubiquitous as DNA/RNA and Appear to Represent Greater Molecular Diversity 7 Big Picture: Nucleotide Sugars Connection of • UDP-Glc, • UDP-Gal, • UDP-GlcNAc, Glycoconjugate • UDPGalNAc, • UDP-GlcA, Biosynthesis • UDP-Xyl, • GDP-Man, • GDP-Fuc, to Intermediary • CMP-Neu5Ac used for synthesizing Metabolism glycoconjugates, e.g, glycoproteins & glycolipids 8 Important Topics to Consider 1. The different types of monosaccharides found in animal cell glycoconjugates 2. The different types of glycoconjugates and their differences, e.g. glycoproteins, glycolipids 3. The nucleotide sugars, glycosyltransferases, glycosidases, transporters, endoplasmic reticulum, and Golgi in terms of their roles in glycoconjugate biosynthesis and turnover 4. -
Pyrolysis of the Simplest Carbohydrate, Glycolaldehyde (CHO-CH2OH), and Glyoxal in a Heated Micro-Reactor
Pyrolysis of the Simplest Carbohydrate, Glycolaldehyde (CHO-CH2OH), and Glyoxal in a Heated Micro-Reactor Jessica Porterfield1, Joshua H. Baraban1, Tyler P. Troy2, Musahid Ahmed2, Michael C. McCarthy3, Kathleen M. Morgan4, John W. Daily5, Thanh Lam Nguyen6, John F. Stanton6, G. Barney Ellison1 1Department of Chemistry and Biochemistry, University of Colorado, Boulder, 80309- 0215, U.S.A., 2Chemical Sciences Division, Lawrence Berkeley National Laboratories, Berkeley, CA 94720, U.S.A., 3Harvard-Smithsonian Center for Astrophysics, Cambridge, MA 02138, 4Department of Chemistry , Xavier University of Louisiana , New Orleans, LA 70125-1098, 5Center for Combustion and Environmental Research, Department of Mechanical Engineering, University of Colorado, Boulder, CO 80309-0427, U.S.A., and 6Department of Chemistry; University of Texas at Austin; Austin, TX 78712. E-mail: [email protected] E-mail: [email protected] E-mail: [email protected] E-mail: [email protected] E-mail: [email protected] E-mail: [email protected] E-mail: [email protected] E-mail: [email protected] E-mail: [email protected] Email: [email protected] J. Physical Chemistry A (revised, March 2016) - 2 - Abstract Both glycolaldehyde and glyoxal have been pyrolyzed in a set of flash- pyrolysis micro-reactors. The pyrolysis products resulting from CHO-CH2OH and HCO-CHO were detected and identified by VUV photoionization mass spectrometry. Complementary product identification was provided by argon matrix infrared absorption spectroscopy. Pyrolysis pressures in the micro- reactor were roughly 100 Torr and contact times with the micro-reactors were approximately 100 µsec. At 1200 K, the products of glycolaldehyde pyrolysis are: H atoms, CO, CH2=O, CH2=C=O, HCO-CHO. -
Intermediate Transfer Type Ink Jet Recording Method
Europaisches Patentamt J European Patent Office © Publication number: 0 606 490 A1 Office europeen des brevets EUROPEAN PATENT APPLICATION published in accordance with Art. 158(3) EPC © Application number: 93914949.8 int. ci.5: B41J 2/01 @ Date of filing: 02.07.93 © International application number: PCT/JP93/00914 © International publication number: WO 94/01283 (20.01.94 94/03) © Priority: 02.07.92 JP 175384/92 Inventor: HOSONO, Yoshie 02.07.92 JP 175385/92 Seiko Epson Corporation, 02.07.92 JP 175386/92 3-5, Owa 3-chome 02.07.92 JP 175387/92 Suwa-shi, Nagano 392(JP) 16.10.92 JP 278938/92 Inventor: NAKAMURA, Hiroto 05.11.92 JP 296109/92 Seiko Epson Corporation, 05.11.92 JP 296110/92 3-5, Owa 3-chome 05.11.92 JP 296111/92 Suwa-shi, Nagano 392(JP) 06.01.93 JP 665/93 Inventor: KOIKE, Yoshiyuki Seiko Epson Corporation, © Date of publication of application: 3-5, Owa 3-chome 20.07.94 Bulletin 94/29 Suwa-shi, Nagano 392(JP) Inventor: MATSUZAKI, Makoto @ Designated Contracting States: Seiko Epson Corporation, CH DE FR GB IT LI NL SE 3-5, Owa 3-chome Suwa-shi, Nagano 392(JP) © Applicant: SEIKO EPSON CORPORATION Inventor: UEHARA, Fumie 4-1, Nishishinjuku 2-chome Seiko Shinjuku-ku Tokyo 163(JP) Epson Corporation, 3-5, Owa 3-chome © Inventor: FUJINO, Makoto Suwa-shi, Nagano 392(JP) Seiko Epson Corporation, Inventor: ISHIBASHI, Osamu 3-5, Owa 3-chome Seiko Epson Corporation, Suwa-shi, Nagano 392(JP) 3-5, Owa 3-chome Inventor: KUMAGAI, Toshio Suwa-shi, Nagano 392(JP) Seiko Epson Corporation, 3-5, Owa 3-chome Suwa-shi, Nagano 392(JP) © Representative: Lewin, John Harvey Inventor: TSUKAHARA, Michinari Elkington and Fife Seiko Epson Corporation, Prospect House CO 8 Pembroke Road o 3-5, Owa 3-chome CO Suwa-shi, Nagano 392(JP) Sevenoaks, Kent TN13 1XR (GB) &) INTERMEDIATE TRANSFER TYPE INK JET RECORDING METHOD. -
Separation and Extraction of Proteins and Polysaccharides from the Seaweed Palmaria Palmata Using Enzyme Digestion
Separation and Extraction of Proteins and Polysaccharides from the Seaweed Palmaria Palmata using Enzyme Digestion by Anna Nilsson Supervisor: Björn Viðar Aðalbjörnsson Co-supervisor: Ph.D. Johan Svensson Bonde Examiner: Professor Leif Bülow 2017 Department of Pure and Applied Biochemistry Faculty of Science Lund University SE-221 00 Lund, Sweden Copywright © 2017 Anna Nilsson All rights reserved Printed in Sweden by Media-Tryck, Lund, 2017 DEPARTMENT OF CHEMICAL ENGINEERING LUND UNIVERSITY P.O. BOX 124 SE-221 00 LUND, SWEDEN ii Organization Document name Lund University Master thesis Date of issue April 2017 Author Anna Nilsson Title and subtitle Separation and Extraction of Proteins and Polysaccharides from the Seaweed Palmaria Palmata using Enzyme Digestion Key words Palmaria palmata, dulse, enzyme digestion, separation, protease, xylan, xylose, seaweed, xylanase Language English, Swedish Recipient’s notes Number of pages 67 iii PREFACE This master thesis was possible thanks to Matís, a food and biotechnology R&D institute located in Reykjavik, Iceland. It commenced 1st of February 2016 and ended with a presentation held the 27/4 2017. The purpose of the project was to find a method of enzymatic extraction of polysaccharides and proteins in Palmaria palmata (P. palmata) a red seaweed. The project focuses mainly on extraction using proteases, which catalyse the hydrolysis of proteins, and xylanase, that catalyse the hydrolysis of xylan. Xylan is the main polysaccharide in P. palmata. The findings intend to be beneficial and useful within the human food and animal feed industry. These new methods and ways to utilize this large ocean resource may lead to more sustainable and environmental solutions compared to already existing terrestrial options such as soy and other grains. -
Expression and Structure-Functional Studies of Human Apolipoproteinciii
Haiqun Liu EXPRESSION AND STRUCTURE-FUNCTIONAL STUDIES OF HUMAN APOLIPOPROTEINCra A thesis submitted in accordance with the regulations of the University of London for the degree of Doctor of Philosophy October 2000 Centre for the Genetics of Cardiovascular Disorders Department of Medicine The Rayne Institute University College London ProQuest Number: U642127 All rights reserved INFORMATION TO ALL USERS The quality of this reproduction is dependent upon the quality of the copy submitted. In the unlikely event that the author did not send a complete manuscript and there are missing pages, these will be noted. Also, if material had to be removed, a note will indicate the deletion. uest. ProQuest U642127 Published by ProQuest LLC(2015). Copyright of the Dissertation is held by the Author. All rights reserved. This work is protected against unauthorized copying under Title 17, United States Code. Microform Edition © ProQuest LLC. ProQuest LLC 789 East Eisenhower Parkway P.O. Box 1346 Ann Arbor, Ml 48106-1346 ABSTRACT Apolipoprotein (Apo) CHI plays a key role in triglyceride (TG)-rich lipoprotein metabolism and is a risk factor for coronary heart disease (CHD). The study involved in this thesis is the first in vitro structure-functional study using recombinant apoCni proteins. The physicochemical properties of recombinant wild type and A23T, a naturally occurring mutation that is associated with apoCIII deficiency and lower plasma TG levels, as well as three site-directed mutants of apoCIII, designed by molecular modelling and implicated in lipid binding (L9T/T20L, F64A/W65A) or lipoprotein lipase (LPL) inhibition (K21A), were compared. Relative lipid binding efficiencies of each apoCIII variants to 1.2-dimyristoyl-sn-glycero-3- phosphatidylcholine (DMPC) were: L9T/T20L>WT>K21A>A23T>F64A/W65A with an inverse correlation with size of the discoidal complexes formed. -
Structures and Characteristics of Carbohydrates in Diets Fed to Pigs: a Review Diego M
Navarro et al. Journal of Animal Science and Biotechnology (2019) 10:39 https://doi.org/10.1186/s40104-019-0345-6 REVIEW Open Access Structures and characteristics of carbohydrates in diets fed to pigs: a review Diego M. D. L. Navarro1, Jerubella J. Abelilla1 and Hans H. Stein1,2* Abstract The current paper reviews the content and variation of fiber fractions in feed ingredients commonly used in swine diets. Carbohydrates serve as the main source of energy in diets fed to pigs. Carbohydrates may be classified according to their degree of polymerization: monosaccharides, disaccharides, oligosaccharides, and polysaccharides. Digestible carbohydrates include sugars, digestible starch, and glycogen that may be digested by enzymes secreted in the gastrointestinal tract of the pig. Non-digestible carbohydrates, also known as fiber, may be fermented by microbial populations along the gastrointestinal tract to synthesize short-chain fatty acids that may be absorbed and metabolized by the pig. These non-digestible carbohydrates include two disaccharides, oligosaccharides, resistant starch, and non-starch polysaccharides. The concentration and structure of non-digestible carbohydrates in diets fed to pigs depend on the type of feed ingredients that are included in the mixed diet. Cellulose, arabinoxylans, and mixed linked β-(1,3) (1,4)-D-glucans are the main cell wall polysaccharides in cereal grains, but vary in proportion and structure depending on the grain and tissue within the grain. Cell walls of oilseeds, oilseed meals, and pulse crops contain cellulose, pectic polysaccharides, lignin, and xyloglucans. Pulse crops and legumes also contain significant quantities of galacto-oligosaccharides including raffinose, stachyose, and verbascose. -
Chapter 3: the Chemical Basis for Life Lesson 2: Organic Compounds
Chapter 3: The Chemical Basis for Life Lesson 2: Organic Compounds We have already learned that water is the primary substance for life on Earth, but we will now explore the element found in most of the molecules from which living organisms are made. That element is carbon and it is found in all organic compounds. The picture above is a graphic depiction of the organic compounds: carbohydrates, proteins, lipids, and nucleic acids. These are all large complex molecules that have contributed to the great diversity of life on Earth. Lesson Objectives • Define and explain elements and compounds; the relationships from atom to molecule to macromolecule. • Explain why carbon is essential to life on Earth and uniquely suited to form biological macromolecules. • Describe and compare the structure and function of the four major types of organic compounds. Vocabulary • atom biochemical conversion biological macromolecule carbohydrate DNA (deoxyribonucleic acid) isomers lipids macromolecules molecule monomer nucleic acid organic molecule polymer protein 63 INTRODUCTION If you look at your hand, what do you see? Of course, you see skin, which consists of cells. But what are skin cells made of? Like all living cells, they are made of matter. In fact, all things are made of matter. Matter is anything that takes up space and has mass. Matter, in turn, is made up of chemical substances. In this lesson you will learn about the chemical substances that make up living things. CHEMICAL SUBSTANCES A chemical substance is matter that has a definite composition. It also has the same composition throughout. A chemical substance may be either an element or a compound. -
University of Huddersfield Repository
University of Huddersfield Repository Ngehnyuiy, Ngo Hansel Characterisation of Bacterial Polysaccharides Original Citation Ngehnyuiy, Ngo Hansel (2020) Characterisation of Bacterial Polysaccharides. Doctoral thesis, University of Huddersfield. This version is available at http://eprints.hud.ac.uk/id/eprint/35297/ The University Repository is a digital collection of the research output of the University, available on Open Access. Copyright and Moral Rights for the items on this site are retained by the individual author and/or other copyright owners. Users may access full items free of charge; copies of full text items generally can be reproduced, displayed or performed and given to third parties in any format or medium for personal research or study, educational or not-for-profit purposes without prior permission or charge, provided: • The authors, title and full bibliographic details is credited in any copy; • A hyperlink and/or URL is included for the original metadata page; and • The content is not changed in any way. For more information, including our policy and submission procedure, please contact the Repository Team at: [email protected]. http://eprints.hud.ac.uk/ CHARACTERISATION OF BACTERIAL POLYSACCHARIDES NGO HANSEL NGEHNYUIY, MSc A thesis submitted to the University of Huddersfield in partial fulfilment of the requirements for the degree of Doctor of Philosophy Department of Chemical and Biological Sciences School of Applied Sciences The University of Huddersfield March 2020 i ABSTRACT A number Gram-positive bacterial strains including Lactobacillus paracasei DG, Lactobacillus salivarius CCUG44481 and Bifidobacteria breve 7017 have been known to possess probiotic properties which has led to their increasing use in commercial probiotic products. -
Apparatus for Auto-Pretreating Sugar Chain
(19) & (11) EP 2 207 030 A1 (12) EUROPEAN PATENT APPLICATION published in accordance with Art. 153(4) EPC (43) Date of publication: (51) Int Cl.: 14.07.2010 Bulletin 2010/28 G01N 27/62 (2006.01) G01N 30/06 (2006.01) G01N 30/72 (2006.01) G01N 30/88 (2006.01) (2006.01) (21) Application number: 08836267.8 G01N 35/04 (22) Date of filing: 03.10.2008 (86) International application number: PCT/JP2008/068111 (87) International publication number: WO 2009/044900 (09.04.2009 Gazette 2009/15) (84) Designated Contracting States: • MIURA, Yoshiaki AT BE BG CH CY CZ DE DK EE ES FI FR GB GR Sapporo-shi HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT Hokkaido 001-0021 (JP) RO SE SI SK TR • YAMAZAKI, Hiroshi Designated Extension States: Hachioji-shi AL BA MK RS Tokyo 192-0031 (JP) • HORIUCHI, Michio (30) Priority: 05.10.2007 JP 2007262771 Hachioji-shi 05.10.2007 JP 2007262680 Tokyo 192-0031 (JP) • MOTOKI, Hiroaki (71) Applicants: Hachioji-shi • Hokkaido University Tokyo 192-0031 (JP) Kita-ku • KURODA, Toshiharu Sapporo-shi Hachioji-shi Hokkaido 060-0808 (JP) Tokyo 192-0031 (JP) • SYSTEM INSTRUMENTS CO., LTD. •KITA,Yoko Hachioji-shi, Tokyo 192-0031 (JP) Amagasaki-shi • Shionogi&Co., Ltd. Hyogo 660-0813 (JP) Osaka-shi, Osaka 5410045 (JP) • NAKANO, Mika Amagasaki-shi (72) Inventors: Hyogo 660-0813 (JP) • NISHIMURA, Shinichiro Sapporo-shi (74) Representative: Guder, André Hokkaido 001-0021 (JP) Uexküll & Stollberg • SHINOHARA, Yasuro Patentanwälte Sapporo-shi Beselerstraße 4 Hokkaido 001-0021 (JP) 22607 Hamburg (DE) (54) APPARATUS FOR AUTO-PRETREATING SUGAR CHAIN (57) To provide an autoanalyzer for analyzing a sug- for the mass spectrometry having the captured sugar ar chain contained in a biological sample, in particular, chain dotted thereon which comprises the step of provid- serum.