SEC: Community_Broadsheet DT: 10-14-2013 ZN: UCI ED: 1 PG #: 1PG: Cover BY: ldodson TI: 10-11-2013 16:27 CLR: CMYK

MONDAY,OCT.14, 2013 UC IRVINE Living Textbook HEALTH Joint effort is required to manage diabetes

By DR. PING H. WANG UC IRVINE

This is the second in a two- part series about the increasing health and economic threat posed by diabetes and how peo- ple can work together for pre- vention, treatment and cure.

UC Irvine scientists are in- vestigating the mechanisms of diabetes and the disease’s complications and are devel- oping new treatments. Our team of physicians, nurses, and educators work together with our patients and their ED CRISOSTOMO, ORANGE COUNTY REGISTER families to execute an inte- From left are UC Irvine assistant coaches Ben Orloff and Daniel Bibona, and director of operations Eric Deragisch. grated diabetes management program. Even though our ef- forts will help our patients and Three former advance diabetes science, it will take a combined effort of UC Irvine standouts individual responsibility, im- proved health care and hospi- reunite on Anteaters’ tal systems, research funding LIFE AFTER and political will to manage staff after their the diabetes pandemic. Doing nothing is not an option. major-league dreams Let’s tackle individual re- sponsibility first. There are 7 don’t work out. million Americans with undi- BASEBALL agnosed diabetes and 26 mil- lion with pre-diabetes. You The UC Irvine They led the Anteat- may be one of them. Please vis- baseball staff is in a ers to a No. 1 national it your doctor for a checkup if light mood. It’s the ranking in 2009, com- you haven’t had a physical re- offseason, so assist- piling the second-high- cently, especially if you have ant coaches Ben Or- est win total in UCI his- experienced an increase in thirst or appetite, more fre- loff and Daniel Bibona MIRIN tory at 45-15. Orloff and and director of oper- FADER Bibona also were part SEE DIABETES ● PAGE 3 ations Eric Deragisch REGISTER of the 2007 team that can take a quick WRITER took UCI to its only ap- break from work. pearance in the College The three friends are spin- World Series. ning in wheeling chairs, one “There was something scooting as fast as he can to really pure about it,” said Or- tag the other while the third loff. “We were just kids going waits to get both of them. to school, playing baseball be- Here in the office over- cause we loved it.” looking , They’re a few years re- the three former UCI ath- moved from the records they letes can act like college kids helped set, as the dazzle of again, reliving memories their FILE PHOTO: ERIC FRANCIS, THE ASSOCIATED PRESS ANA VENEGAS, THE REGISTER UC Irvine pitcher Scott Gorgen, right, celebrates a win formed at Cicerone Field, dreams has faded. Each came Dr. Ping Wang teaches at the over Arizona State in the 2007 College World Series in where they helped put UCI UC Irvine School of Medicine. Omaha, Neb. Orloff and Bibona were on the 2007 team. on the college baseball map. SEE BASEBALL ● PAGE 4 Atwist called flipping A new teaching technique inverts traditional methods of instruction.

By SHERRI CRUZ teracts with the students and seems to be working. ORANGE COUNTY REGISTER helps them solidify concepts. “I really liked it,” said Scarlet Students might be assigned to Reyes, a junior who took Eich- Mathematics teacher Sarah watch short YouTube video lec- horn’s flipped calculus class last Eichhorn and her UC Irvine co- tures at home to get familiar with a spring. “I thought it was a very ef- horts gather every couple of weeks basic concept. They come to class ficient method of teaching.” to talk about their experiences ready to work on problems. Reyes liked being able to watch, “flipping” – not houses, but class- That’s it. That’s flipping. pause and replay videos at home. rooms. “Flipping is the newest and cool- “I would replay it if I didn’t under- Flipping, also called inverting, is est thing I’m trying right now,” stand it.” Then, if she still had a simple idea. It works like this: Eichhorn said. “We’re at various questions, she’d ask the question Students do the most important stages of trying it ourselves and in class. work – the problem solving – in the chatting about what works and Eichhorn began flipping this classroom, not at home. what doesn’t work, and teaching past spring quarter. She used to PAUL BERSEBACH, ORANGE COUNTY REGISTER Instead of the teacher lecturing other people how to flip.” Professor Sarah Eichhorn answers a student’s question during her in the classroom, the professor in- And in Eichhorn’s classroom, it SEE FLIPPING ● PAGE 2 undergraduate calculus class at UC Irvine.

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11 L 20S SEC: Community_Broadsheet DT: 10-14-2013 ZN: UCI ED: 1 PG #: 3PG: PageB BY: pdavenport TI: 10-09-2013 19:02 CLR: CMYK

Orange County Register Monday, Oct. 14,2013 UC Irvine 3

Miray Atamian, a UCI freshman, sits on a friend’s shoul- ders while rocking out in Aldrich Park.

PHOTOS: JEFF ANTENORE, FOR THE REGISTER UCI dance group MCIA performs on stage Sept. 25 during Aldrich Park After Dark, a part of Welcome Week. ALDRICH PARK

Kevin Trinh, a student and a member of the Associated Students of UC Irvine, throws a T- shirt to the audience. AFTER DARK On the night before the first day of classes, hun- dreds of UC Irvine students gathered at Aldrich Park for a special outdoor concert in the dark Sept. 25. Hosted by the Associ- ated Stu- dents of UC Irvine as ANNA part of Wel- ILIFF come Week, REGISTER Aldrich WRITER Park After DJ Hunter performs on campus during the special out- Dark fea- door concert in the dark Sept. 25. tured performances by stu- dent dance groups MCIA and Kaba Modern before music headliners took the stage to start the party. The event featured sing- UCI students take part in er-songwriter J.R. Aquino, the fun at Aldrich Park on best known for his YouTube the night before the first music videos and his ap- day of classes. pearance on the NBC talent show “The Voice,” and con- cluded with Australian dance-pop group Bag Raid- ers, known for their singles “Way Back Home” and “Shooting Stars.” After the concert, stu- Student dance dents headed to The Hill, UC group Kaba Irvine’s on-campus book- Modern shows J.R. Aquino, who appeared on the show "The Voice" a store, for some late-night off some moves. couple of season ago, performs in Aldrich Park. shopping and giveaways.

changing the landscape of standard chow. Now we it was the legal system that DIABETES U.S. health care. It prom- may have a potential new squashed the law, saying ises to be a paperless en- drug for prevention of the Board of Health’s ban terprise in the next few Type 1 diabetes and treat- was not within the “bounds FROM PAGE 1 years. This is an opportuni- ment of Type 2 diabetes of its lawfully delegated au- ty to create new, cheaper and its related metabolic thority.” Bloomberg claims quent urination, or unex- and better models of dia- disorders. This study also more than 2,000 New plained weight gain or loss. betes care. With electronic shows how medical pro- Yorkers have died from the You can reduce the risk of data at our fingertips, we gress can be made through effects of diabetes since the diabetes by maintaining will be able to compare the academic and private-sec- soda ban was prevented ideal body weight, getting effectiveness of different tor partnerships. from going into effect in regular physical exercise programs and how they fit This is just an example March. Similar political and adding healthy foods – specific demographic and of diabetes research pro- skirmishes are bound to fruits, vegetables and lean medical needs. At UC Ir- jects in the works at UC Ir- ensue, praised by public protein – to your diet. Cut- vine Medical Center, we vine, but as we discussed health advocates and ting back on calories is eas- have developed computer- last week, federal funding jeered by critics who decry ier said than done. Eating ized protocols to care for for diabetes research has the creation of “nanny is part of the human surviv- all diabetic patients, been reduced while the states.” Should supersize al instinct and consuming whether they are admitted cost of diabetes has in- sugary beverages be regu- less than what our appetite for surgery, pneumonia, creased rapidly. More re- lated? You decide. calls for is contrary to hu- cancer or any other type of search support will not on- The causes of diabetes man nature. More re- medical condition, and ANA VENEGAS, ORANGE COUNTY REGISTER ly lead to better strategies are complex. The interplay search is needed to under- they will receive the same Dr. Ping Wang, in a lab of the Sue and Bill Gross Stem to reduce suffering from of genetic, environmental stand appetite regulation high-quality care from our Cell Research Center, says technology, research and pol- diabetes, but will also help and social factors is driving and metabolism and to de- team. We are also integrat- itics all play a part in preventing and treating diabetes. the U.S. maintain its posi- this global pandemic. We velop new ways to control ing diabetes care through tion as an innovator and won’t be able to harness body weight. Bariatric sur- all outpatient services to States, present the first ShK-186 for the treatment producer in the global the disease until we fully gery offers an alternative provide access to the most evidence that the drug can- of metabolic syndrome and health care economy. understand its mecha- solution. It’s effective, but advanced treatment. didate – which in March obesity. In the latest study, And finally, there’s the nisms and complications. not without complications. We also need to continue got positive results in a Dr. George Chandy and his political component. New By taking personal respon- Work with your doctor and and grow our research. UC phase-one safety clinical colleagues evaluated York City Mayor Michael sibility, supporting re- dietitian to determine your Irvine scientists have dis- trial – may work in an anti- ShK-186 in tests on obese Bloomberg’s attempt to search and improving our best options. covered that a synthetic obesity and anti-diabetes mice that ate a high-fat, ban super-sized sugary medical systems, we can Second, as we face more compound originally de- capacity. UC Irvine licens- high-sugar diet. They drinks was a political move work together for a health- challenges in our health rived from a sea anemone ed ShK-186 to Kineta Inc., a found that the therapy re- struck down by an appeals ier future. care system, the medical toxin enhances metabolic Seattle-based biotechnolo- duced weight, white fat de- court judge. Under the law, community and hospitals activity and shows poten- gy company, in 2009. It’s posits, liver fat, blood cho- the city’s Department of Dr. Ping Wang, a professor of must help in the battle tial as a treatment for obes- the company’s lead drug lesterol and blood sugar by Health and Mental Hy- medicine at UC Irvine against diabetes by devel- ity and insulin resistance. candidate. Kineta is devel- activating calorie-burning giene would have banned School of Medicine and oping new models of care. The findings, published oping the compound to brown fat, suppressing in- businesses from selling director of UC Irvine Digitization of medical re- earlier this year in the sci- treat autoimmune diseases flammation of white fat sugary beverages larger Diabetes Center, is cords, prescriptions, ad- entific journal Proceedings such as multiple sclerosis, and augmenting liver func- than 16 ounces. Restau- recognized as an internation- ministrative processes and of the National Academy of arthritis and Type 1 Dia- tion. The compound had no rants and business owners al leader in diabetes reimbursement is rapidly Sciences of the United betes. It has also licensed effect on mice that ate voiced their opposition, but treatment and research.