Programme 2015
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London on View The 5th London-Innsbruck Colloquium on Status Epilepticus and Acute Seizures 9-11 April 2015 London, United Kingdom Final Programme www.statusepilepticus2015.eu PATRONS Paracelsus Medical University Christian Doppler Klinik Ignaz Harrer Strasse 79 A-5020 Salzburg, Austria University College London Institute of Neurology Queen Square London WC 1N 3BG United Kingdom CHAIRS Simon Shorvon, London, United Kingdom Eugen Trinka, Salzburg, Austria 3 Contents Welcome Dear friends and colleagues, WELCOME ......................................................................................................................................... 5 Eugen Trinka Simon Shorvon GENERAL INFORMATION. ................................................................................................................ 6 It is our sincere pleasure to welcome you all to London, to this the 5th London-Innsbruck Col- Information FOR SPEAKERS & POSTER PRESENTERS................................................................... 8 loquium on Status Epilepticus and Acute Seizures. These meetings have taken place biennially since 2007, and have become an important fea- SCIENTIFIC PROGRAMME.................................................................................................................. 9 ture of the epilepsy calendar. ThursdaY, 9 APRIL 2015 ................................................................................................... 9 This year, the conference will focus on the clinical and experimental nature of status epilepti- cus and novel aspects of its treatment. It is our intention over the 3 days of the conference to FridaY, 10 APRIL 2015 ..................................................................................................... 12 have intensive and interactive discussion on the cutting edge of research and clinical practice in the field of status epilepticus. We hope to feature current basic and clinical research and to SaturdaY, 11 APRIL 2015 ............................................................................................... 14 provide up-to-date reviews of the field. The aim of the meeting is to stimulate thought and discussion, and to lead to improvements in the treatment and outcome of this condition. LIST OF FACULTY ........................................................................................................................... 16 We have deliberately left space in the programme for the audience to question and to chal- LIST OF POSTERS ........................................................................................................................... 22 lenge - for we believe, as a fundamental pillar of the Colloquia, that academic debate is at the heart of all learning and discovery. We hope you will all join in this endeavour and contribute POSTER ABSTRACTS ...................................................................................................................... 33 to what we hope will be a lively and instructive meeting. SPONSORS AND EXHIBITORS ......................................................................................................... 88 Finally, some acknowledgements are in order. First, we would like to thank our conference organizing team, led by Mrs Ina Kähler, from PCO Tyrol Congress for their tremendous work. Also, the academic activities of this conference would not have been possible without the generous support of our sponsors listed at the back page of this booklet, and we offer our sin- cere thanks to them all. We are grateful too for the patronage of this conference by University College London and Paracelsus Medical University Salzburg. With very best regards Eugen Trinka and Simon Shorvon Co-Chairs, 5th London-Innsbruck Colloquium on Status Epilepticus and Actue Seizures 4 5 General Information General Information Conference venue Coffee breaks and refreshments Great Hall, Sherfield Building Coffee and tea will be served during the official coffee breaks. Lunch will also be provided. All Imperial College, South Kensington Campus refreshments are served in the exhibition area. Londown SW7 2AZ, United Kingdom Smoking Registration Desk at Sherfield Building Smoking is prohibited inside the Sherfield Building. The registration will be located in the entrance area of the Sherfield Building, close to the Queen‘s Tower Rooms City Transportation Opening hours are as follows: Arriving by London Underground Thursday, 9 April 7:30 – 17:30 From South Kensington Station, the campus is only a five minute walk. The College is located Friday, 10 April 7:45 – 18:00 next to the Science Museum. Saturday, 11 April 8:15 – 16:15 Arriving by bus South Kensington Campus is easily accessible by bus. A number of routes pass within easy Congress Organisers walking distance of the campus. PCO Tyrol Congress Congress und Messe Innsbruck GmbH Currency Ms. Ina Kähler and Ms. Sarah Fechner The official currency in the United Kingdom is the Pound. Major credit cards are accep- Rennweg 3 ted in most hotels, shops and restaurants. Automatic teller machines (ATMs) are available 6020 Innsbruck, Austria throughout the city. T: +43-(0)512-575600, F:+43-(0)512-565707 E: [email protected] Name Badges I: www.pco-tyrolcongress.at, www.cmi.at All registered participants receive a name badge together with their registration documents. Please make sure to wear your badge at all times while attending the meeting, exhibition and Trade Exhibition social events. A trade exhibition of pharmaceutical companies and manufacturers of medical equipment is held in the Queen‘s Tower Rooms. Liability and Insurance Neither the organisers, nor the congress secretariat or other suppliers accept liability for per- Exhibition Organisers sonal injuries or loss or damage of property belonging to congress delegates, either during or S12! studio 12 GmbH as a result of the Congress. It is recommended that participants arrange for their own personal Mr. Ralph Kerschbaumer health, accident and travel insurance. Kaiser Josef Straße 9 6020 Innsbruck, Austria Social Programme T: +43-(0)512-890438, F: +43-(0)512-890438-15 Conference Dinner at the Royal College of Physicians (RCP) E: [email protected] Food nourishes the brain and the soul, and at this the 2015 meeting, a rather splendid recep- tion and dinner will be held at the Royal College of Physicians. In addition, there will be an Certificate of Attendance opportunity also to visit the famous building of the College, see items from the College’s mu- All registered delegates receive an official certificate of attendance together with their regis- seum and library, and also to view the temporary exhibition of paintings of medicinal plants. tration documents. Tickets are at EUR 55,00 p.p. Pre-booking is required as tickets are limited! Cloakroom The cloakroom is located on the first floor of the Sherfield Building. 6 7 Information for Speakers & Poster Presenters Scientific Programme Information for speakers THURSDAY APRIL 9th 2015 The Great Hall is equipped with a data projector and a PC for PowerPoint presentations. Please make sure to bring your PowerPoint presentation on a USB-stick to the media check well in 08.30 - 12.30 THE NATURE OF SE: EXPERIMENTAL ASPECTS advance, 2 hours prior to the start of your session at the very latest. Do not bring your own laptop for the presentation. Chair: D. Kullmann (United Kingdom) and J. Kapur (USA) In case your presentation contains video sequences, please ensure to pack them with a stan- dard codec and do not store them in a Quick Time format since this may not be compatible 08.30 - 08.40 Welcome and introduction with PowerPoint presentations. S. Shorvon (United Kingdom) and E. Trinka (Austria) In order to be able to keep the time schedule, please make sure not to exceed the allotted 08.40 - 09.15 Is hypoxia important in status epilepticus? speaking time. G. Biagini (Italy) 09.15 – 09.50 Structural and functional changes in astrocytes following status epilepticus Information for poster presenters K. Wilcox (USA) The poster session is held on Friday, 10th April from 11:55 – 14:00 in the Queen‘s Tower Rooms 09.50 - 10.20 Coffee Break (Sherfield Building). Chair: D. Lowenstein (USA) and A. Rossetti (Switzerland) POSTER FORMAT: Your poster should not exceed 90 cm in width and 150 cm in height (portrait NOT landscape 10.20 – 10.55 What are the physiological bases of GPEDs and other format). Mounting material will be provided on site. EEG patterns in status epilepticus? All posters will be displayed during the entire congress and should be mounted on 9th April in M. van Putten (The Netherlands) the morning. Posters have to be displayed during the whole congress and have to be taken down on Saturday 11th April by the end of the colloquium. Please note that all posters which 10.55 - 11.30 Is spreading depression important in status have not been taken down by their presenters will automatically be removed and discarded. epilepticus? J. Dreier (Germany) POSTER PRESENTATION DETAILS: During the session you or one of your co-authors must be at your poster site and be prepared 11.30 - 12.05 What does burst suppression really mean? to answer questions. F. Amzica (Canada) 12.05 – 12.30 Lunch 8 9 Scientific Programme Scientific Programme 12.30 – 13.30 SATELLITE SYMPOSIUM: 15.00 - 15.30 P2X receptor as a link between hyperexcitability and STATUS EPILEPTICUS – FROM BENCH TO BEDSIDE – neuroinflammation in status epilepticus CHALLENGES FOR TRANSLATING NEW MECHANISMS INTO D. Henshall (Ireland) NEW TREATMENTS (Sponsored by