Biochemistry & Molecular Biology…Now What?
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Medical Biochemistry Profile
Medical Biochemistry Profile Updated December 2019 1 Table of Contents Slide . General Information 3-5 . Total number & number/100,000 population by province, 2019 6 . Number/100,000 population, 1995-2019 7 . Number by gender & year, 1995-2019 8 . Percentage by gender & age, 2019 9 . Number by gender & age, 2019 10 . Number of retirees during the three year period of 2016-2018 11 . Links to additional resources 12 2 General information The primary role of the medical biochemist is to study and measure the biochemical abnormalities in human disease. The medical biochemist is trained in the operation and management of hospital biochemistry laboratories and acts as a consultant in all aspects of their use. As an academic specialist, the medical biochemist develops and integrates a basic medical science research program with clinical practice in a field of biochemical interest and maintains an active role as a teacher of clinically-applied biochemistry. Technology-driven specialties such as medical biochemistry require the physician to have a broad awareness of the field at the time of completion of formal training. But the physician must also be prepared for major changes during the ensuing years of practice that are inevitable and the residency period is the time to acquire skills for life-long learning. Source: Pathway evaluation program 3 General information In medical biochemistry, role learning must be supplemented by skills in self-directed learning. It requires ability in problem solving, formulation of hypotheses, the ability to do directed information searches and also the ability to critically appraise data. Medical biochemistry involves pathophysiology (requiring a thorough knowledge of normal and abnormal biochemistry and physiology, and the ability to apply this knowledge to the understanding of human disease); consultation; interpreting results (understanding the principles and limitations of biochemical analyses and applying these concepts to the interpretation of test results); analytical methods; and instrumentation. -
How to Become a Marine Biologist
How to Become a Marine Biologist If you like working in a variety of places, enjoy research and interacting with animals, like math and science, have initiative and can handle working in different conditions you might want to be a Marine Biologist Other advancements or career choices (professor, researcher, PhD etc) A Masters degree will allow you to specialize in marine biological fields like marine mammals or fisheries. You can also go straight from Marine Biologist Your PhD work should include your Masters to your PhD. field research, conferences and publications. Take as many science and math classes as possible. Also look for summer Masters camps and volunteer opportunities to get experience in the field. Reach out to local researchers. College Bachelor's degree in Biology, Marine Science, Oceanography, Fisheries, or other related fields High School Look for internships and field Middle School experience for the summer Attend science camps and other outdoor Attend and present at professional opportunities. Locate researchers doing conferences and try to publish interesting things and open communication your research. with them * Different marine biologist jobs may have more or less requirements. This is a generalized example to get you started on the right path. Marine Biologist Job Description: A marine biologist studies plants and animals that live in the ocean, their behavior and adaptations, roles in the food chain, and how humans can effect these organisms. They often concentrate on a specific organism or habitat. Marine biologists can work out in a field, lab, or in an office depending on the work they are conducting. -
Résumé Writing: Summary/Profile Examples
Résumé Writing: Summary/Profile Examples Dedicated, versatile biochemist with extensive experience in protein research. Special expertise in recombinant protein purification and characterization from eukaryotic and prokaryotic systems. Solid background in enzymology and structural biology. Key skills include: • Working on own initiative and quickly adapting to new projects • Presenting information clearly and concisely in both verbal and written form • Effectively collaborating in a diverse team environment Well-rounded molecular biologist with a background in microbiology, cell biology and bioinformatics. Broad range of experience in mammalian, bacterial, and viral systems. Proficient in assay development and troubleshooting complex systems. Team player with solid written and oral communication skills anchored by a strong publication record. Inflammation scientist with over 8 years multidisciplinary research experience with emphasis on developing excellent communication skills. Key qualifications: • Equally capable of working independently & as an adaptable team member • Skilled at managing, analyzing, and presenting data to a wide variety of audiences • Proven leadership & supervisory abilities, developed through mentoring graduate students, coordinating institute-wide events, and leading journal clubs Protein crystallographer with a background in human kinases, therapeutic antibodies, retroviral proteases and membrane proteins. Extensive experience in protein biochemistry, crystallization and structure determination, expertise in structure-based -
Certified Wildlife Biologist® Application Form Instructions: 1
CERTIFIED WILDLIFE BIOLOGIST® APPLICATION FORM INSTRUCTIONS: 1. Membership in TWS is required to apply for certification. 2. Application must be typed and submitted in English. 3. Applications must be filled out using Adobe Reader software. 4. Supplemental information may be submitted along with a completed application form, if needed. 5. Applicant is responsibile for providing full documentation of educational and professional- level experience as a wildlife biologist. 6. Completed transcripts with evidence of conferral of degrees are required. No application can be processed until a complete application and all supporting materials have been received. 7. Submit completed application to [email protected] 8. Applicants should expect a decision to be made within 4-6 months. TABLE OF CONTENTS General Information.................................................................1 Education..................................................................................2 Completed Courses..................................................................3 Wildlife Management.....................................................4 Wildlife Biology..............................................................6 Ecology...........................................................................8 Zoology.........................................................................10 Botany...........................................................................13 Physical Sciences..........................................................16 Basic -
Physiology, Biochemistry, and Pharmacology of Transporters for Organic Cations
International Journal of Molecular Sciences Editorial Physiology, Biochemistry, and Pharmacology of Transporters for Organic Cations Giuliano Ciarimboli Experimental Nephrology, Department of Internal Medicine D, University Hospital Münster, 48149 Münster, Germany; [email protected] This editorial summarizes the 13 scientific papers published in the Special Issue “Physiology, Biochemistry, and Pharmacology of Transporters for Organic Cations” of the International Journal of Molecular Sciences. In this Special Issue, the readers will find integrative information on transporters for organic cations. Besides reviews on physi- ology, pharmacology, and toxicology of these transporters [1–3], which offer a concise overview of the field, the readers will find original research work focusing on specific transporter aspects. Specifically, the review “Organic Cation Transporters in Human Physiology, Phar- macology, and Toxicology” by Samodelov et al. [1] summarizes well the general as- pects of physiology, pharmacology, and toxicology of transporter for organic cations. The other review “Organic Cation Transporters in the Lung—Current and Emerging (Patho)Physiological and Pharmacological Concepts” by Ali Selo et al. [2] focuses on these aspects of transporters for organic cations in the lung, an important but often ne- glected field. In the paper “Systems Biology Analysis Reveals Eight SLC22 Transporter Subgroups, Including OATs, OCTs, and OCTNs”, by performing a system biology analysis of SLC22 transporters, Engelhart et al. [4] suggest the existence of a transporter–metabolite network. They propose that, in this network, mono-, oligo-, and multi-specific SLC22 transporters Citation: Ciarimboli, G. Physiology, interact to regulate concentrations and fluxes of many metabolites and signaling molecules. Biochemistry, and Pharmacology of In particular, the organic cation transporters (OCT) subgroup seems to be associated with Transporters for Organic Cations. -
BIOCHEMISTRY MAJOR the Biochemistry Major Is Offered Through the Department of Chemistry
BIOCHEMISTRY MAJOR The Biochemistry major is offered through the Department of Chemistry. This sequence is recommended for students planning entry into graduate school in Biochemistry, Pharmacology, or related subjects. It is also strongly recommend for those desiring to pursue medical or dental school. NOTE: This course sequence may be modified to include a Senior Capstone Experience. FIRST YEAR Fall Semester Credits Spring Semester Credits General Chemistry I for Majors (CHE111) 3 General Chemistry II for Majors (CHE112) 3 General Chemistry I Lab for Majors (CHE111L) 1 General Chemistry II Lab for Majors (CHE112L) 1 General Chemistry I Récitation (CHE111R) 0 General Chemistry II Récitation (CHE112R) 0 Precalculus (MAT116 or MAT120) 3-4 Calculus I (MAT231) 4 First Year Composition (ENG103) 4 Foreign Language (FL201) 4 African Diaspora/World I (ADW111) 4 African Diaspora/World II (ADW112) 4 First Year Experience (FYE 101-Chemistry) 1 First Year Experience (FYE 102-Chemistry) 1 First Year Seminar in Chemistry (CHE101) 0 Big Questions Colloquia (BQC) 1 TOTAL HOURS 16-17 TOTAL HOURS 18 SOPHOMORE YEAR Fall Semester Credits Spring Semester Credits Organic Chemistry I for Majors (CHE231) 4 Organic Chemistry II for Majors (CHE232) 4 Organic Chemistry I Lab (CHE233L) 1 Organic Chemistry II Lab (CHE234L) 1 Organic Chemistry I Récitation (CHE233R) 0 Organic Chemistry II Récitation (CHE234R) 0 Biology of the Cell (BIO120) 4 Organismal Form and Function(BIO115) 4 Calculus II (MAT 232) 4 Physics I: Mechanics & Lab (PHY151) 4 Foreign Language (FL202) -
Biochemistry and Molecular Biology
School of Life Sciences / Department of Biochemistry and Biophysics BIOCHEMISTRY AND MOLECULAR BIOLOGY Revealing how life works Department of Biochemistry and Biophysics Oregon State University 2011 Agriculture and Life Sciences Building Corvallis, OR 97331 OSUBB 541-737-4511 biochem.oregonstate.edu College of Science Oregon State University 128 Kidder Hall Corvallis, OR 97331 541-737-4811 science.oregonstate.edu This publication will be made available in an accessible alternative format upon request. Please contact the College COLLEGE OF SCIENCE of Science at 541-737-4811 or [email protected]. ACADEMIC BROCHURE / 2020 Highlights • Solve problems at the What will you discover? intersection of biological and physical sciences with our The Department of Biochemistry and Biophysics offers nationally accredited program world-class faculty, a tradition of interdisciplinary in biochemistry, molecular and research, teaching excellence and extraordinary cellular biology, chemistry, laboratories to facilitate undergraduate learning. molecular genetics, physics and statistics. The department ranks high nationally and internationally in many research areas, including signal transduction, gene • Tailor your education to expression, epigenetics, metabolic regulation, structural specific career goals with three biology, and genetic code expansion technology. different options. The department offers two Bachelor of Science degrees, • Thrive in a smaller, supportive both accredited by the American Society for Biochemistry department within a world-class and Molecular Biology (ASBMB): research university. • Biochemistry and Molecular Biology (BMB) with • Pursue interdisciplinary research options in Advanced Molecular Biology, Computational projects with faculty across OSU. Molecular Biology, and Pre-medicine; • Participate in the Biochemistry • Biochemistry and Biophysics (BB) with options in Club for community, leadership Advanced Biophysics, Neuroscience, and Pre-medicine. -
And Even-Length, Medium-Chain Fatty Acids in Plants (Amino Adds/Elongtin) ANTOANETA B
Proc. Nadl. Acad. Sci. USA Vol. 91, pp. 11437-11441, November 1994 Biochemistry A pathway for the biosynthesis of straight and branched, odd- and even-length, medium-chain fatty acids in plants (amino adds/elongtin) ANTOANETA B. KROUMOVA, ZHIYI XIE, AND GEORGE J. WAGNER* Plant Physiology/Biochemistry/Molecular Biology Program, Agronomy Department, University of Kentucky, Lexington, KY 40546-0091 Communicated by Martin Gibbs, July 25, 1994 ABSTRACT Pathways and enzymes offatty acid synthase- and even-length scFAs are synthesized via modified mediated, long-even-chain (generally C16-C20) fatty add syn- branched-chain amino acid (bcAA) metabolism in tobacco thesis are well studied, and general metabolism involved in trichome glands (6, 7). It is possible that at least branched and short-chain (Cs-C7) fatty acid biosynthesis is also understood. odd-length mcFAs are formed in this tissue similarly. Alter- In contrast, mechanism of medinm-chain (C#-C14) fatty acid natively, primers derived from bcAA metabolism may be synthesis are unclear. Recent work suggests involvement of elongated by fatty acid synthase (FAS), as suggested for chain-elongation-terminating thloesterases in medium-chain tomato trichomes (8) and tobacco epidermis (9). fatty acid formation in oilseeds and animals. We have shown The classical pathway for bcAA (Val, Leu, Ileu) biosyn- that iso- and anteiso-branched and straigbt, odd- and even- thesis in microorganisms (and largely by inference in plants, length, short-chain fatty adds esterifled in plant-trichome- ref. 10) is shown in the shaded areas of Fig. 1. Key activities gland-produced sucrose esters are synthesized by using carbon involved in branched-chain formation (reactions 1, 1A, and 2) skeletons provided by modified branched-chain amino acid are those catalyzing leucine biosynthesis in all organisms and metabolism/catablis. -
Biochemistry Major University of Michigan - Department of Chemistry Effective 9/2017 ______
Biochemistry Major University of Michigan - Department of Chemistry Effective 9/2017 _____________________________________________________________________________________________ Biochemistry is, literally the chemistry of life. Biochemists seek to understand the chemical principles that underpin all living organisms. Biochemistry is central to medical science as almost all diseases and drugs act to change the body’s chemistry. Advances in biochemistry directly impact the fields of biotechnology, pharmaceutical science, agriculture and environmental science, among many others. The B.S. major in Biochemistry is for those are interested in learning about life from a chemical perspective. Students will be well equipped for graduate studies in biochemistry, chemical biology, and many other fields of inquiry in the life sciences. The degree will also provide excellent preparation for students intending to pursue professional careers in industry and medicine. Prerequisites Course # Course Description Term Term Credits Completed Typically Offered CHEM 210 Structure and Reactivity I F, W, Sp 4 CHEM 211 Investigations in Chemistry: Laboratory F, W, Sp 1 CHEM 215 Structure and Reactivity II F, W, Sp 3 BIO 171 Introductory Biology: Ecology and Evolution F, W, Sp, Su 4 BIO 172 Introductory Biology: Molecular Cellular and Developmental F, W, Sp 4 MATH 115 Calculus I F, W, Sp, Su 4 MATH 116 Calculus II F, W, Sp, Su 4 One of the Following: CHEM 262 Mathematical Methods for Chemists F, W 4 OR MATH 215 Calculus III F, W, Sp, Su 4 One of the Following -
The Meaning of Systems Biology
Cell, Vol. 121, 503–504, May 20, 2005, Copyright ©2005 by Elsevier Inc. DOI 10.1016/j.cell.2005.05.005 The Meaning of Systems Biology Commentary Marc W. Kirschner* glimpse of many more genes than we ever had before Department of Systems Biology to study. We are like naturalists discovering a new con- Harvard Medical School tinent, enthralled with the diversity itself. But we have Boston, Massachusetts 02115 also at the same time glimpsed the finiteness of this list of genes, a disturbingly small list. We have seen that the diversity of genes cannot approximate the diversity With the new excitement about systems biology, there of functions within an organism. In response, we have is understandable interest in a definition. This has argued that combinatorial use of small numbers of proven somewhat difficult. Scientific fields, like spe- components can generate all the diversity that is cies, arise by descent with modification, so in their ear- needed. This has had its recent incarnation in the sim- liest forms even the founders of great dynasties are plistic view that the rules of cis-regulatory control on only marginally different than their sister fields and spe- DNA can directly lead to an understanding of organ- cies. It is only in retrospect that we can recognize the isms and their evolution. Yet this assumes that the gene significant founding events. Before embarking on a def- products can be linked together in arbitrary combina- inition of systems biology, it may be worth remember- tions, something that is not assured in chemistry. It also ing that confusion and controversy surrounded the in- downplays the significant regulatory features that in- troduction of the term “molecular biology,” with claims volve interactions between gene products, their local- that it hardly differed from biochemistry. -
Biochemistry and Molecular Biology (BMB) 1
Biochemistry and Molecular Biology (BMB) 1 BMB 372. Advanced Molecular Biology. (3 h) BIOCHEMISTRY AND Presents molecular mechanisms by which stored genetic information is expressed including the mechanisms for and regulation of gene MOLECULAR BIOLOGY (BMB) expression, protein synthesis, and genome editing. Emphasizes analysis and interpretation of experimental data from the primary literature. Also Interdisciplinary Major listed as BIO 372. P-BIO 213 and 214 and BIO 370/BMB 370/CHM 370 or BIO 265 and BIO 370/BMB 370/CHM 370. This interdisciplinary Bachelor of Science major, jointly offered by the Departments of Biology and Chemistry, provides a strong foundation BMB 372L. Advanced Molecular Biology Laboratory. (1.5 h) in biological chemistry and molecular biology, and related topics at Introduces modern methods of molecular biology to analyze and the interface of these two disciplines. The major is designed to build manipulate expression of genes and function of gene products. Also conceptual understanding and practical and critical thinking skills to listed as BIO 372L. P or C-BIO 372/CHM 372 or BMB 373/CHM 373. address current biological, biochemical, and biomedical challenges. A BMB 373. Biochemistry II. (3 h) required research experience spanning multiple semesters, culminating Examines the structure, function, and synthesis of proteins and nucleic in a senior project, will give students strong experimental skills and acids and includes advanced topics in biochemistry including catalytic provide insight into biochemical and molecular biological experimental mechanisms of enzymes and ribozymes, use of sequence and structure approaches and results that demonstrate the function of biological databases, and molecular basis of disease and drug action. -
Biochemistry Metabolism
Biochemistry Metabolism 07.11.2017 – 27.11.2017 Photosynthesis Gerhild van Echten-Deckert Tel. 73 2703 E-mail: [email protected] www.limes-institut-bonn.de Photosynthesis Light reaction: - Light absorption, generation of a high energy electron and oxidation of water - Electron transport from water to NADPH and generation of a proton-motive force -Synthesis of ATP Berg, Tymoczko, Stryer: Biochemistry “Dark reaction”: - CO2 conversion into carbohydrates consuming ATP and NADPH (Calvin Cycle) Photosynthesis is localized to the thylakoid membranes Lodish et al. Molecular Cell Biology Comparison of photosynthesis and oxidative phosphorylation Berg, Tymoczko, Stryer: Biochemistry Chlorophyll a is the main pigment capturing energy of light Lodish et al. Molecular Cell Biology Energy diagram indicating the electronic states of chlorophyll and their most important modes of interconversion Other light-absorbing pigments, such as carotenoids, extend the range of light that can be absorbed and used for photosynthesis The action spectrum of photosynthesis matches the absorption spectra of chlorophyll a and b and of -carotene The absorption of photons from two distinct photosystems (PSI and PSII + is required for complete electron flow from H2O to NADP Berg, Tymoczko, Stryer: Biochemistry Light absorption by reaction-centre chlorophylls causes a charge separation across the thylakoid membrane The energy of the absorbed light is used to strip an electron from a chlorophyll molecule of the reaction centre to a primary electron acceptor thereby acquiring a positive charge (generation of a strong oxidizing- and a strong reducing agent) Lodish et al. Molecular Cell Biology Subsequent electron flow and coupled proton movement Lodish et al.