PP62-FrontMatter ARI 20 April 2011 14:6 by Universidad Nacional de la Plata on 05/30/11. For personal use only. Annu. Rev. Plant Biol. 2011.62:1-23. Downloaded from www.annualreviews.org PP62CH01-vanMontagu ARI 4 April 2011 16:10 It Is a Long Way to GM Agriculture Marc Van Montagu Institute of Plant Biotechnology for Developing Countries, Department of Plant Biotechnology and Genetics, Ghent University, Ghent 9000, Belgium; email:
[email protected] Annu. Rev. Plant Biol. 2011. 62:1–23 Keywords First published online as a Review in Advance on Agrobacterium, crown gall, Ti plasmid, T-DNA, opines, vir genes, February 11, 2011 T-DNA binary vector, plant genetic engineering, plant genetic The Annual Review of Plant Biology is online at modification, GM plants, GMO plant.annualreviews.org This article’s doi: Abstract 10.1146/annurev-arplant-042110-103906 When we discovered that crown gall induction on plants by Agrobac- Copyright c 2011 by Annual Reviews. terium tumefaciens is a natural event of genetic engineering, we were con- All rights reserved vinced that this was the dawn of a new era for plant science. Now, more 1543-5008/11/0602-0001$20.00 than 30 years later, I remain overawed by how far and how rapidly we progressed with our knowledge of the molecular basis of plant growth, development, stress resistance, flowering, and ecological adaptation, by Universidad Nacional de la Plata on 05/30/11. For personal use only. thanks to the gene engineering technology. I am impressed, but also Annu. Rev. Plant Biol. 2011.62:1-23.