IUGA-ICS Conservative Management Report
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Defecography: Technique, Interpretation, and Current Use Arden M
9 Defecography: Technique, Interpretation, and Current Use Arden M. Morris and Susan C. Parker Defecography, or evacuation proctography, is the on technique, interpretation, and implications dynamic study of expulsion of radiopaque mate- for specific patient populations. rial from the rectum, in order to assess changing anatomic relationships of the pelvic floor and associated organs during evacuation. In 1952, Indications for Testing Wallden 1 first described enteroceles, sigmoido- celes, and rectoceles, using roentgenogram Constipation techniques developed to evaluate patients with symptoms of obstructed defecation. He postu- Defecography was initially developed to assess lated that such outlet obstruction was due to an patients with complaints of constipation and a abnormally deep rectogenital pouch and could sensation of rectal outlet obstruction. The diag- be corrected surgically. However, performing nostic armamentarium has expanded to include these static studies using rectal, vaginal, and anal manometry, electromyography, and colonic small bowel contrast was a cumbersome, expen- transit time studies, all of which are crucial for sive, and embarrassing process for the patient. distinguishing end-organ versus total organ Recognizing the limitations of these studies, etiologies. Therefore, although the major indi- subsequent authors streamlined the procedure cation for performing defecography continues to over the ensuing three decades. be constipation, other complaints may occasion- Broden and Snellman2 proposed the use of ally warrant defecographic evaluation. Table 9.1 cineradiographic methods and a physiologic demonstrates the primary indications and their position, which contributed enormously to the proportionate prevalence among our referred simultaneous study of function and anatomy. patients. There is considerable overlap in many Several centers built radiolucent commodes with of these symptoms and diagnoses. -
An International Urogynecological
AN INTERNATIONAL UROGYNECOLOGICAL ASSOCIATION (IUGA) / INTERNATIONAL CONTINENCE SOCIETY (ICS) JOINT REPORT ON THE TERMINOLOGY FOR FEMALE ANORECTAL DYSFUNCTION Abdul H Sultan^, Ash Monga # ^, Joseph Lee*^, Anton Emmanuel^, Christine Norton^, Giulio Santoro^, Tracy Hull^, Bary Berghmans #^, Stuart Brody^, Bernard T. Haylen *^, Standardization and Terminology Committees IUGA* & ICS#, Joint IUGA / ICS Working Group on Female Anorectal Terminology^ Abdul H Sultan, MB ChB, MD, FRCOG Urogynaecologist and Obstetrician Croydon University Hospital, Croydon. United Kingdom Ash Monga, MB ChB, FRCOG Urogynaecologist Princess Anne Hospital, Southampton. United Kingdom. Joseph Lee, MB ChB, FRANZCOG, CU Urogynaecologist Mercy Hospital for Women, Melbourne. Victoria. Australia. Anton Emmanuel, Gastroenterologist University College Hospital, London. United Kingdom Christine Norton, Professor of Clinical Nursing St Mary's Hospital, London. United Kingdom. Giulio Santoro, Colorectal surgeon Regional Hospital, Treviso. Italy. Tracy Hull, Professor of Surgery Cleveland Clinic Foundation, Cleveland. Ohio. U.S.A. Bary Berghmans, Clinical epidemiologist and physiotherapist Maastricht University Hospital, Maastricht. Netherlands. Stuart Brody, Professor of Psychology University of the West of Scotland, Paisley, United Kingdom Bernard T. Haylen, Professor University of New South Wales, Sydney. N.S.W. Australia. IUGA-ICS Terminology on Female Anorectal Dysfunction Sultan AH et al, Version 25 (16Mar14) Page 1 Correspondence to: Mr Abdul H Sultan, Urogynaecology and -
Análise Da Distribuição Multivetorial De Cargas Do Assoalho Pélvico Feminino Em Diferentes Populações / Licia Pazzoto Cacciari -- São Paulo, 2017
LICIA PAZZOTO CACCIARI Análise da distribuição multivetorial de cargas do assoalho pélvico feminino em diferentes populações Tese apresentada à Faculdade de Medicina da Universidade de São Paulo para obtenção do título de Doutora em Ciências Programa de Ciências da Reabilitação Orientadora: Profa. Dra. Isabel de Camargo Neves Sacco SÃO PAULO 2017 LICIA PAZZOTO CACCIARI Análise da distribuição multivetorial de cargas do assoalho pélvico feminino em diferentes populações Tese apresentada à Faculdade de Medicina da Universidade de São Paulo para obtenção do título de Doutora em Ciências Programa de Ciências da Reabilitação Orientadora: Profa. Dra. Isabel de Camargo Neves Sacco SÃO PAULO 2017 Dados Internacionais de Catalogação na Publicação (CIP) Preparada pela Biblioteca da Faculdade de Medicina da Universidade de São Paulo ©reprodução autorizada pelo autor Cacciari, Licia Pazzoto Análise da distribuição multivetorial de cargas do assoalho pélvico feminino em diferentes populações / Licia Pazzoto Cacciari -- São Paulo, 2017. Tese (doutorado)--Faculdade de Medicina da Universidade de São Paulo. Programa de Ciências da Reabilitação. Orientadora: Isabel de Camargo Neves Sacco. Descritores: 1.Biomecânica 2.Assoalho pélvico. 3.Cargas internas 4.Mulheres 5.Treinamento USP/FM/DBD-228/17 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 Aos meus pais e ao Gui, 22 com muito amor 23 24 iii ACKNOWLEDGEMENTS 25 26 Agradeço a todos que me acompanharam, apoiaram e incentivaram ao longo 27 destes quatro anos de estudo, dedicação e aprendizado. 28 Ao Gui, que se debruçou e se aprofundou comigo em cada conquista e desafio, 29 que tornou possível e prazerosa cada superação que vivenciamos juntos. -
Human Anatomy and Physiology
LECTURE NOTES For Nursing Students Human Anatomy and Physiology Nega Assefa Alemaya University Yosief Tsige Jimma University In collaboration with the Ethiopia Public Health Training Initiative, The Carter Center, the Ethiopia Ministry of Health, and the Ethiopia Ministry of Education 2003 Funded under USAID Cooperative Agreement No. 663-A-00-00-0358-00. Produced in collaboration with the Ethiopia Public Health Training Initiative, The Carter Center, the Ethiopia Ministry of Health, and the Ethiopia Ministry of Education. Important Guidelines for Printing and Photocopying Limited permission is granted free of charge to print or photocopy all pages of this publication for educational, not-for-profit use by health care workers, students or faculty. All copies must retain all author credits and copyright notices included in the original document. Under no circumstances is it permissible to sell or distribute on a commercial basis, or to claim authorship of, copies of material reproduced from this publication. ©2003 by Nega Assefa and Yosief Tsige All rights reserved. Except as expressly provided above, no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or by any information storage and retrieval system, without written permission of the author or authors. This material is intended for educational use only by practicing health care workers or students and faculty in a health care field. Human Anatomy and Physiology Preface There is a shortage in Ethiopia of teaching / learning material in the area of anatomy and physicalogy for nurses. The Carter Center EPHTI appreciating the problem and promoted the development of this lecture note that could help both the teachers and students. -
Evidence Review H: Lifestyle and Conservative Management Options for Pelvic Organ Prolapse
National Institute for Health and Care Excellence Final Urinary incontinence and pelvic organ prolapse in women: management [H] Evidence reviews for lifestyle and conservative management options for pelvic organ prolapse NICE guideline NG123 Evidence reviews April 2019 Final These evidence reviews were developed by the National Guideline Alliance hosted by the Royal College of Obstetricians and Gynaecologists FINAL Error! No text of specified style in document. Disclaimer The recommendations in this guideline represent the view of NICE, arrived at after careful consideration of the evidence available. When exercising their judgement, professionals are expected to take this guideline fully into account, alongside the individual needs, preferences and values of their patients or service users. The recommendations in this guideline are not mandatory and the guideline does not override the responsibility of healthcare professionals to make decisions appropriate to the circumstances of the individual patient, in consultation with the patient and/or their carer or guardian. Local commissioners and/or providers have a responsibility to enable the guideline to be applied when individual health professionals and their patients or service users wish to use it. They should do so in the context of local and national priorities for funding and developing services, and in light of their duties to have due regard to the need to eliminate unlawful discrimination, to advance equality of opportunity and to reduce health inequalities. Nothing in this guideline should be interpreted in a way that would be inconsistent with compliance with those duties. NICE guidelines cover health and care in England. Decisions on how they apply in other UK countries are made by ministers in the Welsh Government, Scottish Government, and Northern Ireland Executive. -
Pelvic Prolapse
Pelvic Prolapse Symptoms and Treatment CYstOCELE RECTOCELE ENTEROCELE COMBINED To make an appointment or ask a question, call the Division of Colon and Rectal Surgery at 617-636-6190. 800 Washington Street For urgent problems, call the Tufts Medical Center Boston, MA 02111 operator at 617-636-5000 and ask for the 617-636-5000 on-call physician for Colon and Rectal Surgery. www.tuftsmedicalcenter.org 09-062 2011 Pelvic prolapse includes several condi- DIAGNOSES REPAIRS tions that occur when pelvic organs bulge Pelvic prolapse may include any of the following specific Surgery may include: down into or out of the vagina or rectum. conditions: ▶ Rectocele repair — rectal approach Most pelvic prolapse occurs in women. ▶ Rectocele: bulging of the rectum into the vagina ▶ Rectocele repair — vaginal approach ▶ Cystocele: bulging of the bladder into the vagina ▶ Rectocele repair — abdominal approach Factors that may increase the risk of pelvic prolapse ▶ Enterocele: bulging of loops of small intestine into ▶ Cystocele repair include: the vagina ▶ TVT — transvaginal tape repair ▶ advancing age ▶ Sigmoidocele: bulging of the sigmoid colon into ▶ Rectal prolapse repair — abdominal ▶ multiple or difficult deliveries the vagina ▶ Rectal prolapse repair — perineal ▶ injury to the pelvic organs or muscles ▶ Urinary incontinence: unable to control urine ▶ Perineoplasty ▶ smoking ▶ Fecal incontinence: unable to control stool or gas ▶ Other ▶ use of steroid medications ▶ Constipation ▶ chronic lung disease ▶ Uterine prolapse Although many women develop some degree of pelvic ▶ Rectal prolapse prolapse as they age, many do not need treatment. ▶ Vaginal prolapse Medical treatment may include pelvic floor exercises, vaginal creams (usually containing estrogen) or use of a pessary (vaginal support ring). -
Prolapse Repair Using Non-Synthetic Material: What Is the Current Standard?
Current Urology Reports (2019) 20:70 https://doi.org/10.1007/s11934-019-0939-8 LOWER URINARY TRACT SYMPTOMS & VOIDING DYSFUNCTION (J SANDHU, SECTION EDITOR) Prolapse Repair Using Non-synthetic Material: What is the Current Standard? Ricardo Palmerola1 & Nirit Rosenblum 1 # Springer Science+Business Media, LLC, part of Springer Nature 2019 Abstract Purpose of Review Due to recent concerns over the use of synthetic mesh in pelvic floor reconstructive surgery, there has been a renewed interest in the utilization of non-synthetic repairs for pelvic organ prolapse. The purpose of this review is to review the current literature regarding pelvic organ prolapse repairs performed without the utilization of synthetic mesh. Recent Findings Native tissue repairs provide a durable surgical option for pelvic organ prolapse. Based on recent findings of recently performed randomized clinical trials with long-term follow-up, transvaginal native tissue repair continues to play a role in the management of pelvic organ prolapse without the added risk associated with synthetic mesh. Summary In 2019, the FDA called for manufacturers of synthetic mesh for transvaginal mesh to stop selling and distributing their products in the USA. Native tissue and non-synthetic pelvic organ prolapse repairs provide an efficacious alternative without the added risk inherent to the utilization of transvaginal mesh. A recent, multicenter, randomized clinical trial demonstrated no clear advantage to the utilization of synthetic mesh. Furthermore, transvaginal native tissue repairs have demonstrated good long-term efficacy, particularly when anatomic success is not the sole metric used to define surgical success. Keywords Pelvicorganprolapse .Cystocele .Enterocele .Rectocele .Syntheticmesh .Transvaginal mesh .Uterosacralligament suspension . -
Engineered Contractile Skeletal Muscle Tissue on a Microgrooved Methacrylated Gelatin Substrate
Engineered Contractile Skeletal Muscle Tissue on a Microgrooved Methacrylated Gelatin Substrate The MIT Faculty has made this article openly available. Please share how this access benefits you. Your story matters. Citation Hosseini, Vahid et al. “Engineered Contractile Skeletal Muscle Tissue on a Microgrooved Methacrylated Gelatin Substrate.” Tissue Engineering Part A 18.23-24 (2012): 2453–2465. As Published http://dx.doi.org/10.1089/ten.tea.2012.0181 Publisher Mary Ann Liebert, Inc. Version Final published version Accessed Fri Aug 21 10:56:46 EDT 2015 Citable Link http://hdl.handle.net/1721.1/77632 Terms of Use Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. Detailed Terms TISSUE ENGINEERING: Part A Volume 18, Numbers 23 and 24, 2012 ª Mary Ann Liebert, Inc. DOI: 10.1089/ten.tea.2012.0181 Engineered Contractile Skeletal Muscle Tissue on a Microgrooved Methacrylated Gelatin Substrate Vahid Hosseini, Pharm.D., M.S.,1,2,* Samad Ahadian, Ph.D.,1,* Serge Ostrovidov, Ph.D.,1 Gulden Camci-Unal, Ph.D.,3,4 Song Chen, Ph.D.,1 Hirokazu Kaji, Ph.D.,5 Murugan Ramalingam, Ph.D.,1,6 and Ali Khademhosseini, Ph.D.1,3,4,7 To engineer tissue-like structures, cells must organize themselves into three-dimensional (3D) networks that mimic the native tissue microarchitecture. Microfabricated hydrogel substrates provide a potentially useful platform for directing cells into biomimetic tissue architecture in vitro. Here, we present microgrooved metha- crylated gelatin hydrogels as a suitable platform to build muscle-like fibrous structures in a facile and highly reproducible fashion. -
Course Details:Details
http://www.unaab.edu.ng COURSE CODE: VBP301 COURSE TITLE: Nerve, Muscle, Sensory, Motor, Autonomic and Integrative Nervous System NUMBER OF UNITS: 3 Units COURSE DURATION: Three hours per week COURSECOURSE DETAILS:DETAILS: Course Coordinator: Dr. Eyitayo Solomon Ajibola, D.V.M, M.Sc. Email: [email protected] Office Location: Dept of Veterinary Physiology/ Pharmacology, COLVET, UNAAB Other Lecturers: Dr. O.E Adeleye COURSE CONTENT: Physiology of nerve and muscle cell, functional classification of neurons, propagation and conduction of nervous impulses; classification of receptors; Ascending sensory pathways; physiology of the special senses; Pyramidal and Extra-pyramidal Motor system, Motor functions of the basal ganglia, the brain stem , Cerebellum, and the Cerebral cortex. The functions of the hypothalamus COURSE REQUIREMENTS: This is a compulsory course for all pre-clinical Veterinary Medical Students. In view of this students are expected to participate in all the course activities and have a minimum of 75% attendance to be able to write the final examination. READING LIST: 1. James G. Cunningham and Bradley G. Klein. Textbook of Veterinary physiology, 4thedition. Saunders Elsevier, Missouri, 2007. 2. Duke’ Physiology of domestic Animals 10TH ed. Cornell University Press, London. 1984 http://www.unaab.edu.ng LECTUREE NOTES NERVE AND SENSORY PHYSIOLOGY SENSORY RECEPTORS They are called selective transducers. They convert the stimulus energy into another form of energy. Sensory transduction converts stimuli into graded potential. Such changes in the receptor membrane potential are known as receptor potential. The stimulus opens ion channel in the receptor membrane. The complexity of sensory receptors ranges from free nerve endings to specialized nerve endings and receptor cells. -
Fluid Osmolarity Acutely and Differentially Modulates Lymphatic Vessels Intrinsic Contractions and Lymph Flow
ORIGINAL RESEARCH published: 05 July 2018 doi: 10.3389/fphys.2018.00871 Fluid Osmolarity Acutely and Differentially Modulates Lymphatic Vessels Intrinsic Contractions and Lymph Flow Eleonora Solari, Cristiana Marcozzi, Daniela Negrini and Andrea Moriondo* Department of Medicine and Surgery, Università degli Studi dell’Insubria, Varese, Italy Lymph formation and propulsion rely on an extrinsic mechanism based on the forces that surrounding tissues exert upon the vessel wall and lumen and an intrinsic mechanism based on spontaneous, rhythmic contractions of the lymphatic muscle layer of collecting vessels. The two spontaneous pacemakers described in literature involve chloride-dependent depolarizations (STDs) and If-like currents, both giving rise to a variable contraction frequency (fc) of lymphatic vessels functional units (lymphangions). Several stimuli have been shown to modulate fc, such as temperature, shear stress, Edited by: and several tissue chemical modulators (prostaglandins, norepinephrine, acetylcholine, Mariappan Muthuchamy, Texas A&M University, United States substance P, and others). However, no detailed description is present in literature on Reviewed by: the acute modulation of fc by means of osmolarity change of the surrounding interstitial Anatoliy A. Gashev, space. Using a well-developed ex-vivo rat diaphragmatic preparation, in which osmolarity Texas A&M University, United States Pierre-Yves Von Der Weid, was changed by varying the concentration of D-mannitol in the perfusing solution and in + − University of Calgary, -
Role of Conventional Radiology and Mri Defecography of Pelvic Floor
Reginelli et al. BMC Surgery 2013, 13(Suppl 2):S53 http://www.biomedcentral.com/1471-2482/13/S2/S53 RESEARCHARTICLE Open Access Role of conventional radiology and MRi defecography of pelvic floor hernias Alfonso Reginelli1*, Graziella Di Grezia1, Gianluca Gatta1, Francesca Iacobellis1, Claudia Rossi1, Melchiore Giganti2, Francesco Coppolino3, Luca Brunese4 From 26th National Congress of the Italian Society of Geriatric Surgery Naples, Italy. 19-22 June 2013 Abstract Background: Purpose of the study is to define the role of conventional radiology and MRI in the evaluation of pelvic floor hernias in female pelvic floor disorders. Methods: A MEDLINE and PubMed search was performed for journals before March 2013 with MeSH major terms ‘MR Defecography’ and ‘pelvic floor hernias’. Results: The prevalence of pelvic floor hernias at conventional radiology was higher if compared with that at MRI. Concerning the hernia content, there were significantly more enteroceles and sigmoidoceles on conventional radiology than on MRI, whereas, in relation to the hernia development modalities, the prevalence of elytroceles, edroceles, and Douglas’ hernias at conventional radiology was significantly higher than that at MRI. Conclusions: MRI shows lower sensitivity than conventional radiology in the detection of pelvic floor hernias development. The less-invasive MRI may have a role in a better evaluation of the entire pelvic anatomy and pelvic organ interaction especially in patients with multicompartmental defects, planned for surgery. Introduction the pelvic examination alone has led to the need to use Pelvic floor disorders represent a significant cause of more direct and comprehensive diagnostic methods [3-6]. morbidity and reduction in quality of life that appear to Purposeofthestudyistodefinetheroleofconven- be increasing in frequency during the last few years [1]. -
Key Points Revision
Key Points Revision 1 Homeostasis and the physiology of proteins 1. Homeostasis is the ability of physiological systems to maintain conditions within the body in a relatively constant state of equilibrium. 2. Each cell in the body benefits from homeostasis, and in turn each cell contributes its share towards the maintenance of homeostasis. 3. The most common type of regulation of physiological variables is by negative feedback. 4. A negative feedback system comprises: detectors, comparators and effectors. 5. Some physiological responses use positive feedback, causing rapid amplification, but this is inherently unstable and requires a mechanism to break the feedback loop; examples include action potentials and hormonal control of childbirth. 6. Normal functioning of proteins is essential for life and usually requires binding of proteins to other molecules. The shape of proteins is essential for the binding to occur and small changes in the environment surrounding proteins can modify the shape of proteins. Homeostatic mechanisms prevent such changes from arising in normal circumstances. Physiology at a Glance, Third Edition. Jeremy P.T. Ward and Roger W.A. Linden. © 2013 John Wiley & Sons, Ltd. Published 2013 by John Wiley & Sons, Ltd. Key revision points 2 Body water compartments and physiological fluids 1. Osmotic pressure depends on the number of osmotically active molecules per litre, and is expressed in terms of osmoles. Osmolarity is osmoles per litre, whereas osmolality is osmoles per kg water, which is preferred as it is temperature independent. Isotonic solutions have the same osmotic potential as plasma. Plasma osmolality is ~290 mosmol/kg H2O, and is mostly due to Na+ and Cl– ions.