bioRxiv preprint doi: https://doi.org/10.1101/2020.02.21.959114; this version posted February 25, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY 4.0 International license. Estimating indirect parental genetic effects on offspring phenotypes using virtual parental genotypes derived from sibling and half sibling pairs Liang-Dar Hwang#1, Justin D Tubbs#2, Justin Luong1, Gunn-Helen Moen1,3, Pak C Sham*2,5,6, Gabriel Cuellar-Partida*1, David M Evans*1,7 1The University of Queensland Diamantina Institute, The University of Queensland, Brisbane, Australia 2Department of Psychiatry, The University of Hong Kong, Hong Kong SAR, China 3Institute of Clinical Medicine, University of Oslo 4Population Health Science, Bristol Medical School, University of Bristol, UK. 5Centre for PanorOmic Sciences, The University of Hong Kong, Hong Kong SAR, China 6State Key Laboratory for Cognitive and Brain Sciences, The University of Hong Kong, Hong Kong SAR, China 7Medical Research Council Integrative Epidemiology Unit at the University of Bristol, Bristol, UK #Joint first authors *Joint senior authors Corresponding author: David M Evans Email:
[email protected] Telephone: +61 7 3443 7347 Address: University of Queensland Diamantina Institute Level 7, 37 Kent St Translational Research Institute Woolloongabba, QLD 4102 Australia bioRxiv preprint doi: https://doi.org/10.1101/2020.02.21.959114; this version posted February 25, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity.