09.19.16 Coordinating Global Brain Projects
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Rockefeller University Revenue Bonds, Series 2019A
Moody’s: Aa1 S&P: AA NEW ISSUE (See “Ratings” herein) $46,770,000 DORMITORY AUTHORITY OF THE STATE OF NEW YORK THE ROCKEFELLER UNIVERSITY REVENUE BONDS SERIES 2019A ® Dated: Date of Delivery Due: July 1, as shown on the inside cover Payment and Security: The Rockefeller University Revenue Bonds, Series 2019A (the “Series 2019A Bonds”) are special limited obligations of the Dormitory Authority of the State of New York (the “Authority” or “DASNY”), payable solely from, and secured by a pledge of (i) certain payments to be made under the Loan Agreement dated as of October 31, 2001, as amended and supplemented, including as proposed to be amended by the Proposed Loan Agreement Amendments (as defined and described herein) (the “Loan Agreement”), between The Rockefeller University (the “University” or “Rockefeller”) and the Authority, and (ii) all funds and accounts (except the Arbitrage Rebate Fund and any fund established for the payment of the Purchase Price of Option Bonds tendered for purchase) established under the Authority’s The Rockefeller University Revenue Bond Resolution, adopted October 31, 2001, as amended (the “Resolution”) and a Series Resolution authorizing the issuance of the Series 2019A Bonds adopted on March 6, 2019 (the “Series 2019A Resolution”). The Loan Agreement is a general, unsecured obligation of the University and requires the University to pay, in addition to the fees and expenses of the Authority and the Trustee, amounts sufficient to pay, when due, the principal, Sinking Fund Installments, if any, Purchase Price and Redemption Price of and interest on all Bonds issued under the Resolution, including the Series 2019A Bonds. -
Marc Tessier-Lavigne, a Leading Neuroscientist He Rockefeller University Campaign Mittee
THE Rockefeller university NEWS FOR BENEFACTORS AND FRIENDS OF THE UNIVERSITY • FALL 2011 MESSAGE FROM DONORS CONTRIBUTE $628 MILLION CHAIRMAN RUSSELL L. CARSON CAMPAIGN FOR COLLABORATIVE SCIENCE EXCEEDS $500 MILLION GOAL The University’s eight-year Campaign for Collaborative Science concluded on June 30, 2011, raising $628 million in new gifts and pledges during the tenure of President Paul Nurse. The Campaign exceeded its $500 mil- lion goal and achieved all that we set out to do, and more. The generosity of our bene- factors was extraordinary. This issue of our newsletter celebrates and acknowledges those whose support is helping to advance Rockefeller’s work. As you read these pages, I hope you take pride in the Campaign’s accomplishments, including our new Collab- orative Research Center on the north campus and the 12 laboratory heads we recruited over the last eight years. The conclusion of our Campaign coincid- ed with a turning point in the University’s history. In the 2010–2011 academic year, we said goodbye to a superb president and welcomed an exceptional scientific leader to Goldberg/Esto Jeff campus as his successor. Paul Nurse became photo: president of the Royal Society in London, and Marc Tessier-Lavigne, a leading neuroscientist he Rockefeller University Campaign mittee. “Because of their commitment and generosity, and the former chief scientific officer of for Collaborative Science has conclud- the future of the University looks brighter than ever.” Genentech, succeeded him in mid-March. In ed, surpassing its $500 million goal Of the $628 million contributed to support the this issue, you will learn more about Marc and with new gifts and grants totaling Campaign, $152 million came in the form of flexible his research program in brain development $628 million. -
Elsa C. Y. Yan Department of Chemistry Yale University 225 Prospect Street, New Haven, CT06511 Tel: (203) 436-2509, Email: Elsa
Elsa C. Y. Yan Department of Chemistry Yale University 225 Prospect Street, New Haven, CT06511 Tel: (203) 436-2509, Email: [email protected] Website: http://ursula.chem.yale.edu/~yanlab/Index.html Education • 2000 Ph.D. (Distinction) Columbia University, New York, NY Advisor: Prof. Kenneth B. Eisenthal Thesis Title: Second Harmonic Generation as a Surface Probe for Colloidal Particles • 1999 M.Phil. Columbia University, New York, NY • 1996 M.A. Columbia University, New York, NY • 1995 B.Sc. (First Class Honors) Chinese University of Hong Kong, Hong Kong Professional Appointments 2016- Director of Graduate Studies, Department of Chemistry, Yale University, New Haven, CT 2016- Editor, Biophysical Journal, Cell Press, 2014- Professor of Chemistry, Yale University, New Haven, CT 2012-2014 Associate Professor of Chemistry, Yale University, New Haven, CT 2007-2012 Assistant Professor of Chemistry, Yale University, New Haven, CT 2014- Adjunct Professor, Chinese University of Hong Kong, Hong Kong 2010-2014 Adjunct Associate Professor, Chinese University of Hong Kong, Hong Kong 2004-2007 Postdoctoral Research Associate, Rockefeller University, New York, NY 2005-2006 Adjunct Assistant Professor, Hunter College, CUNY, New York, NY 2000-2004 Postdoctoral Fellow, UC Berkeley, CA (Mentor: Prof. Richard Mathies) Visiting Fellow, Rockefeller University, New York, NY (Mentor: Prof. Thomas Sakmar) 1995-2000 Research Assistant, Columbia University, New York, NY (Mentor: Prof. Kenneth Eisenthal) Honors and Awards • Elected Chair, Gordon Research Conference: -
Louis Licitra-President Born: Syracuse, New York Education: SUNY Delhi, Syracuse University & Rockefeller University Resident of Bucks County for Over 30 Years
Louis Licitra-President Born: Syracuse, New York Education: SUNY Delhi, Syracuse University & Rockefeller University Resident of Bucks County for over 30 years. Worked with FACT for over 15 years Additionally on the local event planning board for Broadway Cares/Equity Fights AIDS Previous positions include President of the New Hope Chamber of Commerce and board member for over 7 years; event planning board for The Rainbow Room LGBTQA youth group; event planning board for New Hope Celebrates PRIDE (local LGBT organization); Additional support and volunteer work with The New Hope Community Association for high school youth job placement; New Hope Arts member; New Hope Historical Society member; and fund-raising/promotion/volunteer assistance for various organizations throughout the year. Currently, co-owner of Rainbow Assurance, Inc., Title Insurance Agency offering title insurance for PA & NJ. Herb Andrus-Vice President Born: Philadelphia Education: University of Pennsylvania & Pratt Institute, Brooklyn, NY Certifications: Education and Intervention Facilitator (CDC certified.) Worked at Family Sevice Association of Bucks County as Facilitator Lifetime resident of Bucks County Volunteered at --William Way Community Center FACT Board for 3 yrs Boyd Oliver-Treasurer Born: McKeesport PA Graduated Grove City College (PA) with degree in accounting Retired CPA with major public accounting, Fortune 500 corporate and small business experience spanning over 30 years. Has owned and operated his own retail/internet businesses. When not traveling around the globe with his partner, he still enjoys the occasional special consulting assignment or project. Member: AICPA (American Institute Of CPA's) Resident of New Hope/Solebury, Bucks County for over 20 years Tim Philpot-Secretary On the board of FACT for two years and served as secretary for the past year. -
Elizabeth a Heller Phd [email protected] | 215.523.7038
Elizabeth A Heller PhD [email protected] | 215.523.7038 Education 2009 PhD Molecular Biology The Rockefeller University, New York, NY, USA 2002 BA Biology, magna cum laude University of Pennsylvania, Philadelphia, PA USA 1998 Diploma, honors in biology Stuyvesant High School, New York, NY USA Research 2016 - Assistant Professor, Department of Pharmacology and positions present Program in Epigenetics The University of Pennsylvania. Philadelphia, PA 2010- Postdoctoral Associate, Department of Neuroscience 2015 Icahn School of Medicine at Mount Sinai, New York, NY. Advisor: Eric J Nestler MD PhD 2003- Graduate Student, Laboratory of Molecular Biology 2009 The Rockefeller University, New York, NY. Advisor: Nathaniel Heintz PhD 1999- Undergraduate Thesis Research. Department of Biology 2002 University of Pennsylvania, Philadelphia, PA. Advisor: Ted Abel PhD 2000 Summer Research Student, Center for Neural Science New York University, New York, NY. Advisors: Joseph LeDoux PhD and Raphael Lamprecht PhD 1994- Westinghouse Research, Public Health Research Institute, New York, NY. 1998 Advisor: Barry Kreiswirth PhD Awards & 2016 Whitehall Foundation Research Grant Honors 2016 Charles E Kaufman Foundation Early Investigator Grant 2016 NARSAD Young Investigator Award 2015 Robin Chemers Neustein Postdoctoral Fellowship 2014 Keystone Symposia Scholarship, Neuroepigenetics 2013 NIDA Director’s Travel Award 2013 NIDA Individual National Research Service Award 2013 Icahn School of Medicine Postdoc Appreciation Award 2013 American College of Neuropsychopharm. Travel Award 2012 NIDA Institutional National Research Service Award 2003 Women & Science Fellowship, The Rockefeller University 2002 Phi Beta Kappa Honors Society Membership 2001 Barry M Goldwater Scholarship nominee 1998 2nd Place, St. John’s University Metro NY Science Fair 1998 Honorable mention, NYC Intl. -
UNDERSTANDING the BRAIN Tbook Collections
FROM THE NEW YORK TIMES ARCHIVES UNDERSTANDING THE BRAIN TBook Collections Copyright © 2015 The New York Times Company. All rights reserved. Cover Photograph by Zach Wise for The New York Times This ebook was created using Vook. All of the articles in this work originally appeared in The New York Times. eISBN: 9781508000877 The New York Times Company New York, NY www.nytimes.com www.nytimes.com/tbooks Obama Seeking to Boost Study of Human Brain By JOHN MARKOFF FEB. 17, 2013 The Obama administration is planning a decade-long scientific effort to examine the workings of the human brain and build a comprehensive map of its activity, seeking to do for the brain what the Human Genome Project did for genetics. The project, which the administration has been looking to unveil as early as March, will include federal agencies, private foundations and teams of neuroscientists and nanoscientists in a concerted effort to advance the knowledge of the brain’s billions of neurons and gain greater insights into perception, actions and, ultimately, consciousness. Scientists with the highest hopes for the project also see it as a way to develop the technology essential to understanding diseases like Alzheimer’sand Parkinson’s, as well as to find new therapies for a variety of mental illnesses. Moreover, the project holds the potential of paving the way for advances in artificial intelligence. The project, which could ultimately cost billions of dollars, is expected to be part of the president’s budget proposal next month. And, four scientists and representatives of research institutions said they had participated in planning for what is being called the Brain Activity Map project. -
From the Neuron Doctrine to Neural Networks
LINK TO ORIGINAL ARTICLE LINK TO INITIAL CORRESPONDENCE other hand, one of my mentors, David Tank, argued that for a true understanding of a On testing neural network models neural circuit we should be able to actu- ally build it, which is a stricter definition Rafael Yuste of a successful theory (D. Tank, personal communication) Finally, as mentioned in In my recent Timeline article, I described existing neural network models have enough the Timeline article, one will also need to the emergence of neural network models predictive value to be considered valid or connect neural network models to theories as an important paradigm in neuroscience useful for explaining brain circuits.” (REF. 1)). and facts at the structural and biophysical research (From the neuron doctrine to neu- There are many exciting areas of progress levels of neural circuits and to those in cog- ral networks. Nat. Rev. Neurosci. 16, 487–497 in current neuroscience detailing phenom- nitive sciences as well, for proper ‘scientific (2015))1. In his correspondence (Neural enology that is consistent with some neural knowledge’ to occur in the Kantian sense. networks in the future of neuroscience network models, some of which I tried to research. Nat. Rev. Neurosci. http://dx.doi. summarize and illustrate, but at the same Rafael Yuste is at the Neurotechnology Center and org/10.1038/nrn4042 (2015))2, Rubinov time we are still far from a rigorous demon- Kavli Institute of Brain Sciences, Departments of provides some thoughtful comments about stration of any neural network model with Biological Sciences and Neuroscience, Columbia University, New York, New York 10027, USA. -
Circuit Neuroscience: the Road Ahead
CORE Metadata, citation and similar papers at core.ac.uk Provided byGR ColumbiaAND University CHALLE AcademicNGE Commons Circuit neuroscience: the road ahead Rafael Yuste HHMI, Department of Biological Sciences, Columbia University, USA Correspondence: [email protected] It is difficult to write about grand challenges in our field without pontificating or pre- tending to show a degree of certainty in assessing the field that I do not possess. I would rather comment on a few of the issues that particularly worry me. Therefore, this article is just a snapshot of our field now, as I see it, and encourage readers to read it as the opinion of just one of their colleagues. My comments are aimed at Circuit Neuroscience. What exactly is Circuit Neuroscience? Rafael Yuste studied Medicine at the Universidad As stated in the mission statement of Frontiers in Neural Circuits, I follow the definition Autonoma and the Fundacion of Circuit Neuroscience as the understanding of the computational function of neural cir- Jimenez Diaz Hospital in Madrid. After a brief period cuits, linking this function with the circuit micro-structure. Within this field, I will address in Sydney Brenner’s group three different types of challenges: scientific, methodological and sociological ones. at the LMB in Cambridge, he obtained his PhD with Larry Katz in Torsten Scientific problems: Wiesel’s laboratory, at I think that it is fair to say that we are profoundly ignorant about the structure and func- Rockefeller University tion of neural circuits. One could say that the goal of our field is to reverse-engineer in New York. -
'River Campus' Project Will Advance Science
FALL 2015 COMMUNITY CONNECTION New ‘River Campus’ project will advance science, and beautify the public East River Esplanade Image from Rafael Viñoly Architects Image from Rafael Viñoly such as benches, high- and low-back lounge seats, and seat walls Construction of a two-acre addition to the located to maximize views; and pedestrian lighting to provide a Rockefeller University campus, including a safe and renewed waterfront experience. A noise barrier will be installed to reduce the impact of FDR traffic on bikers, joggers, and two-story laboratory building, begins this fall. other park users. The design was developed with the participation of Community Board 8 representatives, city council member Ben Kallos, and other An expansion of The Rockefeller University’s campus, to house new members of the local community. To ensure the ongoing upkeep of research space for its world-renowned bioscience faculty, is set to rise this portion of the esplanade, Rockefeller is also establishing a $1 over the FDR Drive between 64th and 68th Streets. To be known as million endowment to fund the maintenance of its landscaping in The David Rockefeller–Stavros Niarchos Foundation River Campus, it perpetuity, and has contributed $150,000 and appointed a board will house a two-story, 135,600 square-foot laboratory building in member to Friends of the East River Esplanade, a conservancy which scientists will conduct studies in genomics, neuroscience, and devoted to the esplanade restoration. immunology, among other fields, addressing some of the world’s most “This construction project is critical for the university’s continued pressing medical needs. -
Hugh C. Hemmings, Jr., MD., Phd As Chairman of the Department Of
Hugh C. Hemmings, Jr., MD., PhD As Chairman of the Department of Anesthesiology, Dr. Hemmings oversees the extensive clinical and basic anesthesiology research program in the department. He has authored over 100 publications including a textbook on basic anesthesiology. His clinical practice focuses on anesthesia for thoracic surgery and other high risk procedures. He leads an active research group investigating the neuropharmacology of general anesthetics, neuroprotection, cell signaling and novel analgesia therapies. A summary of education, training and/or faculty appointments is listed as following: 2018-present Senior Associate Dean for Research 2013-present Chairman and Anesthesiologist-in-Chief, Department of Anesthesiology, Weill Cornell Medical College 2001-present Professor of Pharmacology, Weill Medical College of Cornell University, New York, NY 2000-present Adjunct Faculty, Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 2000-present Attending Anesthesiologist, Weill Medical College of Cornell University, New York, NY 2000-present Professor of Anesthesiology, Weill Medical College of Cornell University, New York, NY 1999-present Vice Chair for Research, Department of Anesthesiology, Weill Medical College of Cornell University, New York, NY 1998-2001 Associate Professor of Pharmacology, Weill Medical College of Cornell University, New York, NY 1996-2000 Associate Attending Anesthesiologist, The New York Hospital, New York, NY 1996-2000 Associate Professor of Anesthesiology, Cornell -
The Brain Activity Map Project and the Challenge of Functional Connectomics
Neuron NeuroView The Brain Activity Map Project and the Challenge of Functional Connectomics A. Paul Alivisatos,1 Miyoung Chun,2 George M. Church,3 Ralph J. Greenspan,4 Michael L. Roukes,5 and Rafael Yuste6,* 1Materials Science Division, Lawrence Berkeley National Lab and Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720, USA 2The Kavli Foundation, Oxnard, CA 93030, USA 3Department of Genetics and Wyss Institute, Harvard Medical School, Boston, MA 02115, USA 4Kavli Institute for Brain and Mind, UCSD, La Jolla, CA 92093, USA 5Kavli Nanoscience Institute and Departments of Physics, Applied Physics, and Bioengineering, California Institute of Technology, Pasadena, CA 91125, USA 6HHMI, Department Biological Sciences, Kavli Institute for Brain Science, Columbia University New York, NY 10027, USA *Correspondence: [email protected] DOI 10.1016/j.neuron.2012.06.006 The function of neural circuits is an emergent property that arises from the coordinated activity of large numbers of neurons. To capture this, we propose launching a large-scale, international public effort, the Brain Activity Map Project, aimed at reconstructing the full record of neural activity across complete neural circuits. This technological challenge could prove to be an invaluable step toward understanding fundamental and pathological brain processes. ‘‘The behavior of large and com- To explore these jungles, neuroscientists bles. Because of this, measuring emer- plex aggregates of elementary have traditionally relied on electrodes gent functional states, such as dynamical particles, it turns out, is not to be that sample brain activity only very attractors, could be more useful for char- understood in terms of a simple sparsely—from one to a few neurons acterizing the functional properties of a extrapolation of the properties of a within a given region. -
Elegant Molecules: [Dr. Stanford Moore] Fulvio Bardossi
Rockefeller University Digital Commons @ RU Rockefeller University Research Profiles Campus Publications Spring 1982 Elegant Molecules: [Dr. Stanford Moore] Fulvio Bardossi Judith N. Schwartz Follow this and additional works at: http://digitalcommons.rockefeller.edu/research_profiles Part of the Life Sciences Commons Recommended Citation Bardossi, Fulvio and Schwartz, Judith N., "Elegant Molecules: [Dr. Stanford Moore]" (1982). Rockefeller University Research Profiles. Book 13. http://digitalcommons.rockefeller.edu/research_profiles/13 This Article is brought to you for free and open access by the Campus Publications at Digital Commons @ RU. It has been accepted for inclusion in Rockefeller University Research Profiles by an authorized administrator of Digital Commons @ RU. For more information, please contact [email protected]. Carbo I Leu ------Asn--------.....) THE ROCKEFELLER UNIVERSITY I 18 _ C,.---------~~----.-- ....---_...980....101_------~ His (P'o) ~-----------His--- ...../IIB RESEARCH 131 170 s 5 Diagram ofspecial pllDOIi\1CIIES features ofbovine 206 N J.L pancreatic deoxyribonuclease. ......------------Thr SPRING 1982 257 Elegant Molecules Asked how he happened to become a biochemist, Professor FROM THE GREEKPROTEIOS: Stanford Moore attributes the choice to gifted teachers of PRIMARY science and a vocational counselor who advised him that there was no future in aeronautical engineering. "But," he adds Proteins comprise the largest part of the solid mattel ofliving with a smile, ''I've never regretted the choice. I can imagine cells. Some proteins, such as the hemoglobin that carries oxy no life more fascinating or more rewarding than one spent gen in red blood cells, are involved in transport and stOrage. exploring the elegant and complicated architecture of organic Many hormones, like insulin, are proteins; they are chemical molecules." messengers that coordinate body activities.