BMJ Publishing Group Limited (BMJ) disclaims all liability and responsibility arising from any reliance Supplemental material placed on this supplemental material which has been supplied by the author(s) BMJ Open 1 SUPPLEMENTARY INFORMATION 2 3 Population differences in vaccine responses (POPVAC): scientific rationale and cross-cutting 4 analyses for three linked, randomised controlled trials assessing the role, reversibility and 5 mediators of immunomodulation by chronic infections in the tropics 6 Gyaviira Nkurunungi1,¶,*, Ludoviko Zirimenya1,¶, Agnes Natukunda1,¶, Jacent Nassuuna1, Gloria 7 Oduru1, Caroline Ninsiima1, Christopher Zziwa1, Florence Akello1, Robert Kizindo1, Mirriam Akello1, 8 Pontiano Kaleebu1, Anne Wajja1, Henry Luzze2, Stephen Cose1,3, Emily L Webb4, Alison M Elliott1,5 for 9 the POPVAC trial team 10 11 1Immunomodulation and Vaccines Programme, Medical Research Council/Uganda Virus Research 12 Institute and London School of Hygiene and Tropical Medicine (MRC/UVRI and LSHTM) Uganda 13 Research Unit, Entebbe, Uganda 14 2Uganda National Expanded Program on Immunisation, Ministry of Health, Kampala, Uganda 15 3Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, United 16 Kingdom 17 4MRC Tropical Epidemiology Group, Department of Infectious Disease Epidemiology, London School 18 of Hygiene and Tropical Medicine, London, United Kingdom 19 ¶These authors contributed equally 20 *Correspondence: Gyaviira Nkurunungi;
[email protected] Nkurunungi G, et al. BMJ Open 2021; 11:e040425. doi: 10.1136/bmjopen-2020-040425 BMJ Publishing Group Limited (BMJ) disclaims all liability and responsibility arising from any reliance Supplemental material placed on this supplemental material which has been supplied by the author(s) BMJ Open 21 Table S1. Uganda National Expanded Programme on Immunisation (EPI) schedule Mode and site of Vaccine/ antigen Dosage and doses required Minimum Interval Between Doses Minimum Age to Start Storage Temperatures Administration Infant vaccines Infants (0-11m) 0.05ml.