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Australia's Longevity Tsunami
Australia’s Longevity Tsunami What Should We Do? WHITE PAPER I Contents exeCutIve SummAry 2 WhAt DO We KNOW? 4 WhAt IS the PrOBLem? 6 WhAt ShOuLD We DO? 9 Key PrINCIPLeS AND SummARY OF POSItIONS 10 Appendix A Life expectancy 16 Appendix B Why We underestimate Life expectancy 23 Appendix C Amendments to Facilitate Innovation in the Annuities market 29 Appendix D retirement and retirement Intentions 31 Appendix e the Case for removing Barriers to Working Longer 32 Appendix F Annuity Products 34 CONtACt DetAILS – ACtuArIeS INStItute 36 Australia’s Longevity Tsunami – What Should We Do? • Actuaries Institute WhIte PAPer – August 2012 1 Executive Summary ustralia is experiencing a major demographic and societal transformation. By 2050, almost a quarter of the population will be aged over 65 compared to 14% now. Australians are already one of the longest lived populations on the planet, and Aour longevity is steadily improving. Australian life expectancies are rising much faster than commonly understood and this has serious social policy implications – especially in economic, retirement incomes, health and welfare policy. Public commentary on life expectancies is normally driven by the annual release of the Australian Bureau of Statistics reports1. these ‘reported’ life expectancies are a snapshot that capture past longevity improvements but make no allowance for expected future improvements. there are efforts made by various arms of Government and other organisations to predict cohort life expectancies, i.e. life expectancies which include projected future mortality improvements. While more realistic, owing to uncertainty of future outcomes there are plausible scenarios where this approach too will underestimate life expectancy. -
SENS-Research-Foundation-2019
by the year 2050, cardiovascular an estimated 25-30 the american 85 percent of adults disease years and older age 85 or older remains the most population will suffer from common cause of 2 1 2 dementia. death in older adults. triple. THE CLOCK IS TICKING. By 2030, annual direct The estimated cost of medical costs associated dementia worldwide was 62% of Americans with cardiovascular $818 billion diseases in the united over age 65 have in 2015 and is states are expected to more than one expected to grow to rise to more than chronic condition.1 3 $2 trillion $818 billion. by 2030.1 References: (1) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732407/, (2) https://www.who.int/ageing/publications/global_health.pdf, (3) https://www.cdcfoundation.org/pr/2015/heart-disease-and-stroke-cost-america-nearly-1-billion-day-medical-costs-lost-productivity sens research foundation board of directors Barbara Logan Kevin Perrott Bill Liao Chairperson Treasurer Secretary Michael Boocher Kevin Dewalt James O’Neill Jonathan Cain Michael Kope Frank Schuler 02 CONTENTS 2019 Annual Report 04 Letter From The CEO 06 Outreach & Fundraising 08 Finances 09 Donors erin ashford photography 14 Education 26 Investments 20 Conferences & Events 30 Research Advisory Board 23 Speaking Engagements 31 10 Years Of Research 24 Alliance 32 MitoSENS 34 LysoSENS 35 Extramural Research 38 Publications 39 Ways to Donate cover Photo (c) Mikhail Leonov - stock.adobe.com special 10th anniversary edition 03 FROM THE CEO It’s early 2009, and it’s very late at night. Aubrey, Jeff, Sarah, Kevin, and Mike are sitting around a large table covered in papers and half-empty food containers. -
Virtualität Und Unsterblichkeit
Oliver Krüger Virtualität und Unsterblichkeit Gott, Evolution und die Singularität im Post- und Transhumanismus https://doi.org/10.5771/9783968216737, am 31.08.2020, 15:40:45 Open Access - https://www.nomos-elibrary.de/agb Oliver Krüger Virtualität und Unsterblichkeit Gott, Evolution und die Singularität im Post- und Transhumanismus https://doi.org/10.5771/9783968216737, am 31.08.2020, 15:40:45 Open Access - https://www.nomos-elibrary.de/agb ROMBACH WISSENSCHAFTEN • REIHE LITTERAE herausgegeben von Gerhard Neumann ( † ), Günter Schnitzler, Maximilian Bergengruen und Thomas Klinkert Band 123 https://doi.org/10.5771/9783968216737, am 31.08.2020, 15:40:45 Open Access - https://www.nomos-elibrary.de/agb Oliver Krüger Virtualität und Unsterblichkeit Gott, Evolution und die Singularität im Post- und Transhumanismus https://doi.org/10.5771/9783968216737, am 31.08.2020, 15:40:45 Open Access - https://www.nomos-elibrary.de/agb Dieses Buch ist mit der Unterstützung der Philosophischen Fakultät und des Hochschulrates der Universität Freiburg (Schweiz) veröffent- licht worden. Bibliografische Information der Deutschen Nationalbibliothek Die Deutsche Nationalbibliothek verzeichnet diese Publikation in der Deutschen Nationalbibliografie; detaillierte bibliografische Daten sind im Internet über <http:/dnb.d-nb.de> abrufbar. © 2019. Rombach Verlag KG, Freiburg i.Br./Berlin/Wien 2. vollständig überarbeitete und erweiterte Auflage. Alle Rechte vorbehalten Umschlag: Bärbel Engler, Rombach Verlag KG, Freiburg i.Br./Berlin/Wien Satz: rombach digitale manufaktur, Freiburg im Breisgau Herstellung: Rombach Druck- und Verlagshaus GmbH & Co. KG, Freiburg i.Br. Printed in Germany ISBN 978-3-7930-9939-0 https://doi.org/10.5771/9783968216737, am 31.08.2020, 15:40:45 Open Access - https://www.nomos-elibrary.de/agb Inhalt Vorwort der zweiten Auflage ������������������������������������������������������������������ 9 Vorwort der ersten Auflage ������������������������������������������������������������������ 11 Who is Who? des Post- und Transhumanismus . -
Transhumanism Engineering the Human Condition
Roberto Manzocco Transhumanism Engineering the Human Condition History, Philosophy and Current Status Springer Praxis Books More information about this series at http://www.springer.com/series/4097 Roberto Manzocco Transhumanism - Engineering the Human Condition History, Philosophy and Current Status Roberto Manzocco Gorizia, Italy SPRINGER-PRAXIS BOOKS IN POPULAR SCIENCE ISSN 2626-6113 ISSN 2626-6121 (electronic) Popular Science ISBN 978-3-030-04956-0 ISBN 978-3-030-04958-4 (eBook) Springer Praxis Books https://doi.org/10.1007/978-3-030-04958-4 Library of Congress Control Number: 2019930046 © Springer Nature Switzerland AG 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. -
Cristina Dolan 8 Michael Ventura 10 David Gram 12 Markus Peschl 14
BEYOND 2030 Jowita Michalska DEAR READERS, Innovation, disruption, transformation. New technol- Jowita ogies and the digital revolution. Artifi cial intelligence, IoT, blockchain... Technology develops exponentially. Michalska And it does not wait for us in the distant future, nor "around Digital University CEO, the corner", but shapes our reality just here and now. Ambassador Technology a ects how we live and work, how we learn, of Singularity University and how we can heal. in Poland For many years I have been watching how technologies change busi- nesses and societies around the world. I can see how dynamically we operate also in Poland, although I can clearly see that we still lack access to high-quality education and the latest knowledge. Thanks to cooper- ation with such organizations as Singularity University and recognized international experts – pioneers and innovators share in their fi elds – it is possible to transfer know-how, experience, as well as thoughts and opinions on the most important topics related to the future. Events such as Masters&Robots organized by Digital University give you the chance to learn about the latest discoveries, tame technologies and implement e ective tools that will improve your life and work. "Beyond 2030" is a unique report – a record of the most interesting con- versations that provide answers to bothering questions from four areas of our lives: society, business, work and medicine. We've invited amazing experts – the most powerful minds, that have been constantly working to ensure that technologies develop and support humanity – to share their knowledge and experience. BEYOND 2030 BEYOND In the publication you will fi nd not only futuristic visions, but above all useful and practical knowledge that opens up to changes, inspires, but also provokes to ask further questions. -
The Past Fifteen Years
The Past Fifteen Years Return on Mission Report 2003-2018 002 Table of History 03 Contents Message 04 Strategies 05 Progress 05-23 Making 90 the new 50 by 2030 Annual Report 2018 003 Introduction Message from our Foundation's CEO I am happy to report that we are winning! It has always been the fervent desire of the As a social engineering effort, the prize has Methuselah Foundation to find itself with been spectacularly successful. Efforts to Dave Gobel nothing left to accomplish. Over the years, engineer life extension have gone from CEO we have been focused on seeking the point practically zero dollars worth of investment of greatest leverage to prevent or reverse the when we began, to well over a billion dollars damage associated with aging. in investment. When we started, the very idea of working on increasing the human lifespan We treat aging the way a medieval diamond would result in career suicide. Now, the cutter would face the challenge of clea- ving one of the most valuable and hardest worldwide community is publicly focused on substances known to man. In an era where extending lifespan and reversing aging. tools were primitive, the gem cutter would Due to these early successes, more and carefully examine the internal crystalline more investors are giving attention and structure, as well as the faults in the dia- funding to our space. In anticipation of this mond. After careful and methodical analysis, sea change, the Methuselah Foundation the gem cutter would strike the diamond created the Methuselah Fund to help curate with a cleaver, which would result in the and direct investments into projects and large diamond breaking into predictable and useful smaller pieces, ready for polishing startups that will move the needle in the and setting in jewelry. -
SENS Research Foundation 2019 Annual Report
by the year 2050, cardiovascular an estimated 25-30 the american 85 percent of adults disease years and older age 85 or older remains the most population will suffer from common cause of 2 1 2 dementia. death in older adults. triple. THE CLOCK IS TICKING. By 2030, annual direct The estimated cost of medical costs associated dementia worldwide was 62% of Americans with cardiovascular $818 billion diseases in the united over age 65 have in 2015 and is states are expected to more than one expected to grow to rise to more than chronic condition.1 3 $2 trillion $818 billion. by 2030.1 References: (1) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732407/, (2) https://www.who.int/ageing/publications/global_health.pdf, (3) https://www.cdcfoundation.org/pr/2015/heart-disease-and-stroke-cost-america-nearly-1-billion-day-medical-costs-lost-productivity sens research foundation board of directors Barbara Logan Kevin Perrott Bill Liao Chairperson Treasurer Secretary Michael Boocher Kevin Dewalt James O’Neill Jonathan Cain Michael Kope Frank Schuler 02 CONTENTS 2019 Annual Report 04 Letter From The CEO 06 Outreach & Fundraising 08 Finances 09 Donors erin ashford photography 14 Education 26 Investments 20 Conferences & Events 30 Research Advisory Board 23 Speaking Engagements 31 10 Years Of Research 24 Alliance 32 MitoSENS 34 LysoSENS 35 Extramural Research 38 Publications 39 Ways to Donate cover Photo (c) Mikhail Leonov - stock.adobe.com special 10th anniversary edition 03 FROM THE CEO It’s early 2009, and it’s very late at night. Aubrey, Jeff, Sarah, Kevin, and Mike are sitting around a large table covered in papers and half-empty food containers. -
A Translational Approach to Enzyme-Mediated Retinal Lipofuscin Removal for Atrophic Age-Related Macular Degeneration and Stargardt's Disease
Please do not remove this page A Translational Approach to Enzyme-Mediated Retinal Lipofuscin Removal for Atrophic Age-Related Macular Degeneration and Stargardt's Disease Moody, Kelsey James https://scholarship.miami.edu/discovery/delivery/01UOML_INST:ResearchRepository/12355252850002976?l#13355471410002976 Moody, K. J. (2019). A Translational Approach to Enzyme-Mediated Retinal Lipofuscin Removal for Atrophic Age-Related Macular Degeneration and Stargardt’s Disease [University of Miami]. https://scholarship.miami.edu/discovery/fulldisplay/alma991031447210902976/01UOML_INST:ResearchR epository Open Downloaded On 2021/09/26 10:17:17 -0400 Please do not remove this page UNIVERSITY OF MIAMI A TRANSLATIONAL APPROACH TO ENZYME-MEDIATED RETINAL LIPOFUSCIN REMOVAL FOR ATROPHIC AGE-RELATED MACULAR DEGENERATION AND STARGARDT’S DISEASE By Kelsey James Moody A DISSERTATION Submitted to the Faculty of the University of Miami in partial fulfillment of the requirements for the degree of Doctor of Philosophy Coral Gables, Florida May 2019 ©2019 Kelsey James Moody All Rights Reserved UNIVERSITY OF MIAMI A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy A TRANSLATIONAL APPROACH TO ENZYME-MEDIATED RETINAL LIPOFUSCIN REMOVAL FOR ATROPHIC AGE-RELATED MACULAR DEGENERATION AND STARGARDT’S DISEASE Kelsey James Moody Approved: _______________________ _______________________ Zafar Nawaz, Ph.D. Feng Gong, Ph.D. Professor of Biochemistry and Associate Professor of Biochemistry Molecular Biology and Molecular Biology _______________________ _______________________ Michal Toborek, M.D., Ph.D. Sanjoy Bhattacharya, Ph.D. Professor of Biochemistry and Professor of Ophthalmology Molecular Biology _______________________ _______________________ Ralf Landgraft, Ph.D. Guillermo Prado, Ph.D. Associate Professor of Biochemistry Dean of the Graduate School and Molecular Biology _______________________ Gerold Feuer, Ph.D. -
Millennial Samurai
GEORGE J. CHANOS a mindset for the 21st century BOOK ONE MILLENNIAL SAMURAI TABLE OF CONTENTS ABOUT THE AUTHOR FOREWORD INTRODUCTION ���������������������������������������������������������������� MILLENNIALS ������������������������������������������������������������������������������������������������ SAMURAI.......................................................................................................... MILLENNIAL SAMURAI ������������������������������������������������������������������������������ THE RIGHT MINDSET ������������������������������������������������������� CRITICAL THINKING ���������������������������������������������������������������������������������� CONTROL YOUR THOUGHTS ������������������������������������������������������������������ SET CLEAR INTENTIONS �������������������������������������������������������������������������� BELIEVE IN YOURSELF ������������������������������������������������������������������������������� THINK FOR YOURSELF ������������������������������������������������������������������������������� OPEN YOUR MIND ��������������������������������������������������������������������������������������� INTUITION ������������������������������������������������������������������������������������������������������ SEEK THE TRUTH ����������������������������������������������������������������������������������������� ATTITUDE........................................................................................................ EMPATHY........................................................................................................ -
Financial Institutions – Challenges and Opportunities
BEYOND 2030 Jowita Michalska DEAR READERS, Innovation, disruption, transformation. New technol- Jowita ogies and the digital revolution. Artifi cial intelligence, IoT, blockchain... Technology develops exponentially. Michalska And it does not wait for us in the distant future, nor "around Digital University CEO, the corner", but shapes our reality just here and now. Ambassador Technology a ects how we live and work, how we learn, of Singularity University and how we can heal. in Poland For many years I have been watching how technologies change busi- nesses and societies around the world. I can see how dynamically we operate also in Poland, although I can clearly see that we still lack access to high-quality education and the latest knowledge. Thanks to cooper- ation with such organizations as Singularity University and recognized international experts – pioneers and innovators share in their fi elds – it is possible to transfer know-how, experience, as well as thoughts and opinions on the most important topics related to the future. Events such as Masters&Robots organized by Digital University give you the chance to learn about the latest discoveries, tame technologies and implement e ective tools that will improve your life and work. "Beyond 2030" is a unique report – a record of the most interesting con- versations that provide answers to bothering questions from four areas of our lives: society, business, work and medicine. We've invited amazing experts – the most powerful minds, that have been constantly working to ensure that technologies develop and support humanity – to share their knowledge and experience. BEYOND 2030 BEYOND In the publication you will fi nd not only futuristic visions, but above all useful and practical knowledge that opens up to changes, inspires, but also provokes to ask further questions. -
Download Issue
THE WORLD’S LEADING CEOS EXPLAIN: How to secure your position at the top The CEO Academy A 2-Day Program of Corporate Leadership Immersion Brought to you by the Wharton School of the University of The premier forum for CEOs aiming to improve company performance Pennsylvania and CEO Academy Led by a who’s who of corporate leaders and prominent Wharton faculty, this November 18–19, 2015 intensive high-level forum for CEOs will show you how to circumnavigate the The Harold Pratt House potential challenges inherent in your leadership position and successfully drive your organization forward. 58 E. 68th Street, New York, NY A cross-section of the world’s top business leaders and Wharton faculty will share their success stories on pressing challenges such as: Speakers and faculty include: • Sigal Barsade, Professor of • Navigating shareholder engagement Management, The Wharton School • Utilizing media to your advantage • Developing capital allocation strategies • Edward Breen, Chairman, Tyco • Managing innovation/transformation • Geoffrey Garrett, Dean, The Wharton School This is your roadmap to the top of your game. • Alan Mulally, former CEO, Join world-class peers for an immersive experience that will reaffi rm and refocus your strategy and leadership. This program is exclusively for current Ford Motor Company and newly appointed CEOs. For more information or to register: WhartonCEOAcademy.com | Contact Donna Gregor: +1.215.656.5348 | [email protected] Features 4 CEO LETTER Tapping the “Fountain A Doctor In Every of Youth” Career Pocket and Purse 14 6 THE LATEST THINKING Should CEOs Preach? Precision Medicine Gets Precise 22 Medicine Goes Retail 28 8 Q&A Tony Coles, M.D., cofounder, chairman and CEO, Yumanity Therapeutics 36 Q&A Bernard J. -
Top 100 Longevity Charities the Non-Profit Ground of the Longevity Industry
Top 100 Longevity Charities The Non-Profit Ground of the Longevity Industry www.aginganalytics.com Top-100 Longevity Charities Table of Contents Executive Summary 3 Top Charities Overview 47 - Supportive, Palliative, Geriatric, Political Introduction 10 53 Organizations Report Methodology 19 - Organizations Concentrated on Basic Research and 60 Direct Application Thereof The Role and Importance of Longevity Charities 25 - Organizations Concentrated on Disruptive 67 Engineering Solutions Top Charities Infographics 28 AI for Longevity, Precision Medicine, and Biomarkers of 69 Aging as Most Prospective Field for Charities - Report MindMap 29 Top-100 Longevity Charities Profiles 72 - Distribution by Region 33 - Distribution by Category 35 Key Report Observations 174 - Distribution by Main Field of Research 40 Disclaimer 175 Introduction The fight against age-related disease, and the politics of old age and social care in general, have, since the middle of the 20th century, traditionally been associated with the non-profit sector. But in fact the nonprofit sector has been a catalyst for reform at every stage in metamorphosis of Longevity from a science to technology, and from the technology to the industry. It was disease charities such as Alzheimer’s Research UK and American Aging Association, which led the early social and biomedical crusades against familiar diseases of aging, and in so doing become familiar names themselves. And it was biomedical non-profits such as the Buck Institute for Aging and the Max Planck Institute for Biology of Ageing which created and developed the tech sectors which have since come to comprise the current, multi-faceted industry . But more importantly, it was the nonprofit sector which dominated the industry until perhaps only three years ago, and laid the groundwork for the modern commercial industry.