Figure S-1: Gene Ontology Categories Classification (Panther) of All Identified Regulated Proteins According to Their Cellular Functions

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Figure S-1: Gene Ontology Categories Classification (Panther) of all identified regulated proteins according to their cellular functions. Proteins were assigned to 16 biological processes and 11 molecular function categories. Figure S-1 Figure S-2: Visualization of time-related effects by Voronoi Treemaps of CAP treated vs. untreated S9 epithelial cells. Identified proteins were assorted into individualised KEGG-BRITE hierarchy followed by the extraction of the sub-class “oxidative stress” (A). Oxidative stress related proteins were displayed for the time courses from 0 h up to 72 h (B). Every tile in that structural hierarchy, representing one identified protein, was coloured by fold-changes (logarithmic normalized expression values from Delta-2D of CAP treated samples divided by expression values of untreated controls). The colour gradient encodes expression changes: white coloured tiles show expressions, which correspond to a fold change of ‘1’. Blue shaded tiles represent proteins with negative fold-changes (lower expression in CAP treated samples in comparison to the untreated controls) and shades of orange represent proteins with fold-changes higher than ‘1’. Saturation of blue and orange is reached at an expression rate five times higher or lower than the corresponding control. The six different time points 0 h, 0.5 h, 1 h, 24 h, 48 h and 72 h are displayed. Figure S-2 CAP Table S-1 Table S-1: Register of all 1504 significant protein spots of the S9 epithelial cells passed the One-way ANOVA test (p-value ≤ 0.05) )1 hit ID obtained from Delta2D analysis (Delta2D statistically software version 4.4, Decodon (Germany, Greifswald)) )2 protein identification corresponding to human proteins (UniProt-SwissProt database; Rel. 51.

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