Effect of Potassium Lactate and a Potassium Lactate-Sodium Diacetate Blend on Listeria Monocytogenes Growth in Modified Atmosphere Packaged Sliced Ham

Total Page:16

File Type:pdf, Size:1020Kb

Effect of Potassium Lactate and a Potassium Lactate-Sodium Diacetate Blend on Listeria Monocytogenes Growth in Modified Atmosphere Packaged Sliced Ham 2297 Journal of Food Protection, Vol. 70, No. 10, 2007, Pages 2297-2305 Copyright ©, International Association for Food Protection Effect of Potassium Lactate and a Potassium Lactate-Sodium Diacetate Blend on Listeria monocytogenes Growth in Modified Atmosphere Packaged Sliced Ham L. A. MELLEFONT* AND T. ROSS Australian Food Safety Centre of Excellence, Tasmanian Institute of Agricultural Research, School of Agricultural Science, University of Tasmania, Private Bag 54, Hobart 7001, Tasmania, Australia MS 07-051: Received 30 January 2007/Accepted 9 May 2007 ABSTRACT Two commercially available organic acid salts, potassium lactate (PURASAL HiPure P) and a potassium lactate-sodium diacetate blend (PURASAL Opti.Form PD 4), were assessed as potential inhibitors of Listeria monocytogenes growth in modified atmosphere packaged (MAP) sliced ham in challenge studies. The influence of the initial inoculation level of L. monocytogenes (101 or 103 CPU g-I) and storage temperature (4 or g0C) was also examined. The addition of either organic acid salt to MAP sliced ham strongly inhibited the growth of L. monocytogenes during the normal shelf life of the product under ideal refrigeration conditions (4°C) and even under abusive temperature conditions (i.e., g0C). During the challenge studies and in the absence of either organic acid salt, L. monocytogenes numbers increased by l,OOO-fold after 20 days at goC and IO-fold after 42 days at 4°C. Both organic acid salt treatments were found to be listeriostatic rather than listericidal. The addition of either organic acid salt to the MAP ham also reduced the growth of indigenous microflora, i.e., aerobic microflora and lactic acid bacteria. The influence of these compounds on the risk of listeriosis in relation to product shelf life is discussed. Unlike most foodbome pathogens, Listeria monocyto­ modify or treat long shelf life refrigerated products in such genes can grow, albeit slowly, at refrigeration temperatures, a way that the growth of L. monocytogenes is prevented, at in the presence of >5% salt, and in the absence of oxygen least within the normal shelf life of the product. Organic (37). Processed meats, including ham and pate, are often acids and their salts, applied singly and in combination, packaged under vacuum or modified atmospheres and have been shown by many studies to prevent or greatly stored under refrigeration to extend their shelf life, typically retard the growth of L. monocytogenes in processed meats being 6 to 8 weeks or more. Although initial contamination under both recommended temperatures of storage (at or be­ with L. monocytogenes, when present, is usually low, i.e., low 4°C) and mild temperature abuse (e.g., up to 10°C). <10 CPU g-l (15, 28), its potential for growth in ready­ Generally, studies have focused on the activity of the so­ to-eat meats that are eaten without further cooking prior to dium salts (2-4, 9, 14, 17, 18,21,22,27,29,31, 34, 40), consumption is, prima facie, considerable. Moreover, it is but several also consider potassium lactate or potassium well documented that L. monocytogenes can grow in many lactate in combination with sodium diacetate (19, 26, 32, such products during refrigerated storage, and such foods 33). Most studies have considered the activity of organic have caused, or been strongly implicated in, outbreaks of acid salts in sausage products (e.g., bratwurst, frankfurters, foodbome listeriosis that have resulted in fatalities (6-8, 23, saveloys), but others have studied their effectiveness in 25). cooked ham (4, 34). Mbandi and Shelef (21) considered the L. monocytogenes present on raw ingredients can be effectiveness in sterile uncooked comminuted beef emul­ killed reliably by the heat treatments routinely applied dur­ sion. ing smallgoods processing. During slicing and packaging There are a range of commercial products available after processing, however, recontamination can occur (16, based on the salts of organic acids that are intended to pro­ 18, 24, 30, 39). During the past decade, the food industry vide protection against the growth of undesirable microor­ has implemented hygiene practices and technologies that ganisms on foods. This project was undertaken to assess have greatly reduced the prevalence of L. monocytogenes the antilisterial efficacy of two such products on an Aus­ tralian smallgoods product, specifically, PURASAL HiPure on ready-to-eat foods (20, 28). Nevertheless, the ecology P (potassium lactate) and PURASAL Opti.Form PD 4 (a of the organism, particularly its ability to colonize food potassium lactate-sodium diacetate blend). The influence, processing plants (38), still results in L. monocytogenes be­ and possible interaction, of the presence of either antilis­ ing detected, typically, in -1 to 5%, or more, of processed terial product, the initial level of L. monocytogenes, and the meat products (1, 5, 15, 20, 28, 41). temperature of storage on the development of populations One approach to minimize the risk of listeriosis is to of L. monocytogenes in modified atmosphere packaged * Author for correspondence. Tel: + 61 (0)3 62 266278. Fax: + 61 (0)3 (MAP) sliced ham are investigated. The influence of indig­ 62 267450; E-mail: lyndal.mel1efo~utas.edu.au. enous microbiota is also considered. 2298 MELLEFONT AND ROSS ~ J. Food Prot., Vol. 70, No. 10 MATERIALS AND METHODS aging. Uninoculated control samples were prepared by adding 0.1 ml of sterile pw. To minimize the potential for cross-contamina­ Ham preparation. Hams were prepared under commercial tion, these control samples were prepared prior to the samples conditions by a large Australian manufacturer. During processing, requiring inoculation with the L. monocytogenes. antilisterial treatments were applied to hams prior to cooking. The To preserve the integrity of the gas mixture, a self-adhesive treatments were as follows: the addition of 3% (wtJwt finished rubber septum was applied to each sample package, and the sy­ product) of PURASAL Opti.Form PD 4 (a blend consisting of ringe was inserted into the pack through the septum. An inoculum 54.5 to 57.5% potassium lactate and 3.7 to 4.3% sodium diacetate: volume of 0.1 ml was added to a comer of the base of the package Purac Asia Pacific Pte. Ltd., Singapore) or the addition of 3% (wtJ wt finished product) of PURASAL HiPure P (58 to 62% potas­ that did not contain any ham. The package was then inverted and sium lactate). Both products were provided to the smallgoods pro­ gently shaken (by hand) so that the slices of ham moved across ducer by Fibrisol Service Australia Pty. Ltd. (Heatherton, Victoria, the inner surfaces of the container and each other. This was done Australia). Finished hams were sliced by the manufacturer and to maximize the likelihood of even distribution of cells of L. packaged in -50-g lots into commercial thermoformed ridge bot­ monocytogenes or sterile diluent throughout the sample. Imme­ tom packs, composed of polyethylene teraphthalate and polyeth­ diately after inoculation (or addition of sterile PW), the septum ylene, and produced on horizontal form fill. The packages were was covered with self-adhesive tape. Inoculated samples were ap­ propriately labeled and incubated at either 4 or 8°C in walk-in then sealed under MAP (30% CO2 and 70% N2) . Control and treated samples were transported to the laboratory by commercial cool-rooms. The duration of storage was :5.76 and :5.57 days for transport operators under refrigeration, but no temperature records samples stored at 4 and 8°C, respectively. were available. Sampling. At appropriate time intervals, three samples from Bacterial strains. Five strains of L. monocytogenes were each treatment or control were assessed for levels of L. monocy­ used in combination for all "inoculated" samples. L. monocyto­ togenes, concentrations of lactic acid bacteria, and aerobic plate genes Scott A (type strain) and L5/22 (cold-smoked salmon iso­ count (APC). The entire sample from each package was asepti­ late) were obtained from the School of Agricultural Science, Uni­ cally removed and diluted I: I in PW and stomached for 2 min. versity of Tasmania. Strains 20425, 20432, and 20423, all envi­ Further W-fold dilutions in PW were prepared as required, and ronmental isolates from a smallgoods factory, were supplied by 100- or 250-111 aliquots were surface plated with a spiral plater Silliker Microtech Pty., Ltd., Melbourne, Victoria, Australia. (Autoplate 4000, Spiral Biotech Inc., Bethesda, Md.) onto agar Strains were maintained on bead suspensions in nutrient broth plates as follows. PALCAM plates (Oxoid CM877, and SRl50 (Oxoid CMl, Oxoid Ltd., Hampshire, UK) with 15% glycerol and antibiotic supplement) for L. monocytogenes were incubated aer­ stored at -70°C. obically at 37°C for 48 h. The deMan Rogosa Sharpe agar (Oxoid Preparation of inocula. Before each experiment, isolates CM361) plates for lactic acid bacteria were incubated aerobically were resuscitated from cryogenic storage by plating onto brain at 25°C for 72 h. Plate count agar plates (Oxoid CM463 APHA heart infusion agar (Oxoid CM225) and incubating at 25°C for 48 Standard Plate Count Agar) for APCs were incubated at 20°C for h. A primary culture of each strain was prepared by touching a 72 h. Colonies were counted manually, and log(viable cell count) sterile loop to five colonies and inoculating 10 ml of prewarmed of the triplicate samples was averaged (±standard deviation) and (25°C) tryptone soya broth (Oxoid CM129) containing 0.6% yeast plotted against time. The maximum sample volume plated was extract (TSBYE; Oxoid L21). The primary culture for each strain 250 111 of the I: 1 dilution on quadruplicate plates. This permitted was incubated without shaking at 37°C for 24 h. The primary a maximum test sensitivity of 2 CFU g-I. cultures were then serially diluted in 0.1% peptone water (PW; Water activity (Aqualab CX2, Decagon Devices, Pullman, Oxoid Bacteriological Peptone L37 containing 0.85% NaCl) and Wash.) and direct measurement of the pH (pH meter 250A.
Recommended publications
  • No. 747 for Calcium Lactate in Potato and Vegetable Snacks and Sweetened Crackers
    GRAS Notice (GRN) No. 747 https://www.fda.gov/Food/IngredientsPackagingLabeling/GRAS/NoticeInventory/default.htm Exponent 11 50 Connecticut Ave., NW EXponenr Suite 11 00 Washington, DC 20036 telephone 202-772-4900 facsim ile 202-772-4979 www.exponent.com November 14, 2017 Office ofFood Additive Safety (HFS-200) Center for Food Safety and Applied Nutrition Food and Drug Administration 500 l Campus Drive College Park, MD 20740 Subject: GRAS Notification for the Use of Calcium Lactate in Potato and Vegetable Snacks and Sweetened Crackers Project No. 1607280.000 Dear Sir/Madam: In accordance with 2 1 CFR part 170, subpart E, PepsiCo, hereby provides a notice of a claim that the food ingredient described in the enclosed notification document is excluded from the premarket approval requirement ofthe Federal Food, Drug, and Cosmetic Act because the notifier has concluded such use to be generally recognized as safe (GRAS), based on scientific procedures. One paper copy of the notification is provided as required; we also have provided a copy ofthe notification on the enclosed CD-ROM. Ifyou have any questions or require additional information, please do not hesitate to contact me at 202-772-4915, or [email protected]. Sincerely, (b) (6) Nga Tran, DrPH, MPH Principal Scientist ~~©~U~~~ 1607280.000- 04 16 NOV 16 20'7 000001 OFFICE OF FOOD A001TlVE SAFEi'Y ( GRAS Conclusion for the Use of Calcium Lactate in Potato and Vegetable Snacks and Sweetened Crackers SUBMITTED BY: PepsiCo, Inc 700 Anderson Hill Road Purchase, NY 10577 SUBMITTED TO: U.S. Food and Drug Administration Center for Food Safety and Applied Nutrition Office of Food Additive Safety HFS-200 5100 Paint Branch Parkway College Park, MD 20740-3835 CONTACT FOR TECHNICAL OR OTHER INFORMATION: Nga Tran Principal Scientist Exponent, Inc.
    [Show full text]
  • Milk Allergy
    Allergic reactions Allergic reactions are severe adverse reactions that occur when the body’s immune system overreacts to a particular allergen.These reactions may be caused by food, insect stings, latex, medications and other substances. In Canada, the nine priority food allergens Milk are peanuts, tree nuts, sesame seeds, milk, eggs, seafood (fish, crustaceans and shellfish), soy, wheat One of the nine most and sulphites (a food additive). common food allergens What are the symptoms of an allergic reaction? When someone comes in contact with an allergen, the symptoms of a reaction may develop quickly and rapidly progress from mild to severe. The most severe form of an allergic reaction is called anaphylaxis. Symptoms can include breathing difficulties, a drop in blood pressure or shock, which may result in loss of consciousness and even death. A person experiencing an allergic reaction may have any of the following symptoms: • Flushed face, hives or a rash, red and itchy skin • Swelling of the eyes, face, lips, throat and tongue • Trouble breathing, speaking or swallowing • Anxiety, distress, faintness, paleness, sense of doom, weakness • Cramps, diarrhea, vomiting • A drop in blood pressure, rapid heart beat, loss of consciousness How are food allergies and severe allergic reactions treated? Currently there is no cure for food allergies. The only option is complete avoidance of the specific allergen. Appropriate emergency treatment for anaphylaxis (a severe food allergy reaction) includes an injection of adrenaline, which is available in an auto-injector device. Adrenaline must be administered as soon as symptoms of a severe allergic reaction appear.The injection must be followed by further treatment and observation in a hospital emergency room.
    [Show full text]
  • Sodium Reduction Made Easy with Sub4salt® Cure and Potassium
    facts Sodium reduction made easy with sub4salt ® cure and potassium lactates Introduction There are two important considerations in the preparation of processed meat products. Firstly, a product that remains safe and stable for its entire shelf life is a must. Secondly, there is an increasing demand for healthier meat products. One of the major health trends in the processed meat market is sodium reduction, since these products usually contain high levels of salt. A high sodium intake is associated with negative effects on the human body such as hypertension, strokes and kidney disease. Potassium lactate and blends with acetates or diacetates accommodate both of these considerations. Jungbunzlauer provides solutions for the meat industry that ensure there is no microbiological growth in products over a long period of time, even at low use levels. Furthermore, choosing the right potassium-based ingredient can result in a sodium reduction of over 25% and, in combination with Jungbunzlauer’s sub4salt ® cure, a 1:1 curing salt substitute, a sodium reduction of over 50% is possible. 2 Why reduce sodium? Changing lifestyles and rapid urbanization have caused a shift in dietary patterns to consuming more highly processed food and further from a diet focusing on fresh fruits and vegetables. Processed food is not only usually more calorie-dense and high in saturated fats, trans fats, sugars and salt, but also lower in potassium as this highly soluble mineral is washed out during processing. [20] Due to the reasons above, arteriosclerosis and hypertension are common in the modern Western world leading to cardio - vascular diseases (CVD).
    [Show full text]
  • An Overview of Functional Non-Meat Ingredients in Meat Processing: the Current Toolbox
    PROCESSOR’S CHALLENGES IN ADDRESSING NEW MARKET/CONSUMER DEMANDS An Overview of Functional Non-Meat Ingredients in Meat Processing: The Current Toolbox Joseph G. Sebranek INTRODUCTION ing the use of these “toolbox” ingredients is not only the critical nature of the roles they play but also because these My “assignment” as part of this discussion of the chal- are all multifunctional ingredients. Because they impact lenges facing meat processors trying to meet consumer several important properties of processed meats, attempt- demands for clean labels is to review the critical func- ing to reduce or eliminate these ingredients has implica- tional roles of the fundamental non-meat ingredients that tions for multiple changes in the product. are essential for processed meats. The market pressure for shorter, simpler, easier-to-understand ingredient state- WATER ments is providing considerable motivation for processors to reduce or even eliminate some of the traditional, well- One of the functional non-meat ingredients in the current established non-meat ingredients. However, the practical toolbox that is often overlooked is water. While water applications of many of the traditional non-meat ingredi- is a major component of lean meat, it is also commonly ents have been developed and refined as a result of years, added to many processed meat products, and, as such, decades or even centuries of use, and have clearly evolved becomes a non-meat ingredient. Water plays an impor- to play very critical roles in processed meats. These ingre- tant functional role in processed meats which is likely to dients comprise the “current toolbox” that provides the be modified if other ingredients are changed.
    [Show full text]
  • Folder: Meat Products
    Meat Products Health trends Consumers are increasingly looking for ways to eat healthier. Jungbunzlauer offers food manufacturers customised solutions for creating healthier meat products without compromising on taste or functionality. In order to cater to the top health trends, Jungbunzlauer provides easy-to-use ingredients for reducing the sodium and phosphate content of food products. Sodium reduction The salt substitute sub4salt ® enables manufacturers of meat products to reduce sodium content without compromising on taste. sub4salt ® is a patented mineral salt blend. By using sub4salt ®, the sodium content of the end product can be reduced by up to 50%. Furthermore, it delivers a salty flavour while possessing the same functionality and microbiostatic capacity as salt in food products. As sub4salt ® can replace salt one to one, no adjustment of the standard recipe is required. It can be used in meat products, breading and seasoning in the meat industry as a replacement for salt. Besides sub4salt ®, sub4salt ® cure can be added to cured meat products as a substitute for curing salt, with a resulting sodium reduction of 35%. Sodium lactate and sodium-based lactate/(di)acetate blends used for Listeria control and shelf life extension are the second biggest contributors to the sodium content of processed meat products apart from curing salt. At a typical dosage level of 2.5% of the commercial 60% solution, substituting sodium lactate with potassium lactate reduces the sodium content of meat products by more than 25%. The same reduction leve l can be achieved by exchanging a sodium lactate/sodium (di)acetate blend with a potassium lactate/potassium (di)acetate blend .
    [Show full text]
  • The Effect of Lactate on Nitrite in a Cured Meat System Brooke Nicole Mcclure Iowa State University
    Iowa State University Capstones, Theses and Graduate Theses and Dissertations Dissertations 2009 The effect of lactate on nitrite in a cured meat system Brooke Nicole Mcclure Iowa State University Follow this and additional works at: https://lib.dr.iastate.edu/etd Part of the Animal Sciences Commons Recommended Citation Mcclure, Brooke Nicole, "The effect of lactate on nitrite in a cured meat system" (2009). Graduate Theses and Dissertations. 10939. https://lib.dr.iastate.edu/etd/10939 This Thesis is brought to you for free and open access by the Iowa State University Capstones, Theses and Dissertations at Iowa State University Digital Repository. It has been accepted for inclusion in Graduate Theses and Dissertations by an authorized administrator of Iowa State University Digital Repository. For more information, please contact [email protected]. The effect of lactate on nitrite in a cured meat system By Brooke N. McClure A thesis submitted to the graduate faculty in partial fulfillment of the requirements for the degree of MASTER OF SCIENCE Major: Meat Science Program of Study Committee: Joseph G. Sebranek, Major Professor Dennis Olson Leo Timms Iowa State University Ames, Iowa 2009 ii Table of Contents General Introduction ........................................................................................................ 1 Thesis organization .............................................................................................. 2 Chapter 1. Literature Review .........................................................................................
    [Show full text]
  • “Inert” Ingredients Used in Organic Production
    “Inert” Ingredients Used in Organic Production Terry Shistar, PhD A Beyond Pesticides Report he relatively few registered pesticides allowed in organic production are contained in product formulations with so-called “inert” ingredients that are not disclosed on the T product label. The “inerts” make up the powder, liquid, granule, or spreader/sticking agents in pesticide formulations. The “inerts” are typically included in products with natural or synthetic active pesticide ingredients recommended by the National Organic Standards Board (NOSB) and listed by the National Organic Program (NOP) on the National List of Allowed and Prohibited Substances. Any of the pesticides that meet the standards of public health and environmental protection and organic compatibility in the Organic Foods Production Act (OFPA) may contain “inert” ingredients. Because the standards of OFPA are different from those used by the U.S. Environmental Protection Agency (EPA) to regulate pesticides and given changes in how the agency categorizes inerts, the NOSB has adopted a series of recommendations since 2010 that established a substance review process as part of the sunset review. NOP has not followed through on the Board’s recommendations and, as a result, there are numerous materials in use that have not been subject to OFPA criteria. This report (i) traces the history of the legal requirements for review by the NOSB, (ii) identifies the universe of toxic and nontoxic materials that make of the category of “inerts” used in products permitted in organic production, and (iii) suggests a path forward to ensure NOSB compliance with OFPA and uphold the integrity of the USDA organic label.
    [Show full text]
  • Sodium Lactate and Potassium Lactate Are Synthetic
    April, 2016 Ms. Michelle Arsenault National Organic Standards Board USDA-AMS-NOP 1400 Independence Ave. SW., Room 2648-S, Mail Stop 0268 Washington, DC 20250-0268 Re. HS: Sodium Lactate and Potassium Lactate These comments to the National Organic Standards Board (NOSB) on its Spring 2016 agenda are submitted on behalf of Beyond Pesticides. Founded in 1981 as a national, grassroots, membership organization that represents community-based organizations and a range of people seeking to bridge the interests of consumers, farmers and farmworkers, Beyond Pesticides advances improved protections from pesticides and alternative pest management strategies that reduce or eliminate a reliance on pesticides. Our membership and network span the 50 states and the world. Beyond Pesticides agrees that sodium lactate and potassium lactate must be on the National List in order to be used in organic food. However, we oppose their listing because they are synthetic preservatives and are thus not appropriate for use in organic food. Sodium lactate and potassium lactate are synthetic. As described in the Lactic Acid and Lactates Technical Review (TR), sodium lactate and potassium lactate are manufactured by a reaction of lactic acid with a synthetic chemical, generally sodium or potassium hydroxide. (TR, lines 519-548) Thus, they would be classified as synthetic according to the NOP draft classification guidance. As stated in the Technical Review, the USDA Food Standards and Labeling Policy Book says: It should be noted that meat products that contain sodium and potassium lactates can no longer be labeled as “natural” without a case-by-case assessment of what function these materials are serving in the product, and at what levels (USDA FSIS 2005).
    [Show full text]
  • Food Additives and Allergies/Intolerances
    Food Additives and POWERED BY Allergies/Intolerances Food additives are used for a variety of reasons, including improving flavor or texture, boosting nutritional value and maintaining product safety from production to the pantry. The safety and efficacy of additives are overseen by theU.S. Food and Drug Administration (FDA). While there are documented cases of adverse reactions to certain additives, these are typically not related to an immune-system response and therefore less severe than typical allergic reactions. True allergic reactions, including anaphylaxis, are very rare to most additives. According to the American Academy of Allergy, Asthma and Immunology (AAAAI), there are studies that show adverse reactions to additives, but most reports are of single patients (or small clusters of patients) and are related to dyes and sulfites. How are additives labeled? The FDA requires manufacturers to list all ingredients, in order of predominance, on the label. The label must also list the names of any FDA-certified color additives, but some ingredients can be listed jointly as “natural flavors,” “spices,” or “artificial flavoring” if they are dubbed to be “generally recognized as safe” (GRAS) by the FDA. This also applies to “artificial colors” if the color additive(s) is exempt from certification. If an additive contains any allergen covered by the Food Allergen Labeling Consumer Protection Act (FALCPA)—a list that presently includes egg, milk, peanut, tree nut, soy, wheat, fish, and shellfish—the allergen must be stated on the label. Because there may be recipe or formulary changes at any time, it’s important for people with allergies to read labels every time.
    [Show full text]
  • Milk/Dairy Elimination Diet 2 (For Food Protein Intolerance, Such As Food Protein Induced Enterocolitis, Proctocolitis)
    Leaders In Allergy & Asthma Care For Over 40 Years Milk/Dairy Elimination Diet 2 (For food protein intolerance, such as food protein induced enterocolitis, proctocolitis) This diet eliminates all dairy products. Chocolate is also eliminated because most chocolate contains milk. Read labels for the following words that indicate the presence of milk in a product (this list is not all‐ inclusive, so read labels): Milk (in all forms including Caseinate (in all forms) Lactoglobulin, lactoferrin, lactulose condensed, derivative, dry, Cheese, cottage cheese Nisin evaporated, low‐fat, non‐fat, Cream Nougat pasteurized, powder, protein, Curds Pudding skimmed, solids, whole) Custard Recaldent (some gum and Artificial butter flavor Ghee (clarified butter) toothpaste) Butter/butter fat/ butter oil Goat's milk (and milk from all Sour cream, sour cream solids Buttermilk other animals) Whey/whey solids/whey Casein (casein hydrosylate, rennet Lactalbumin (lactalbumin powder/whey concentrate casein) phosphate) Yogurt & Kefir Avoid the following foods unless the ingredient list indicates a milk‐free product (this list is not all‐ inclusive, so read labels): Baked goods (cookies, cakes, cake Creamy salad dressing and dips Instant mashed potato mixes, muffins, some breads, Desserts (pie, pudding, custard) Malted beverage mix pancakes, biscuits) Frosting Margarine Breakfast cereal (some brands) Gravy Milk‐based formula Candy High protein drink Non‐dairy creamer Caramel Ice cream/sherbet/frozen yogurt Sauces (e.g., Béarnaise) Chocolate Imitation butter flavor
    [Show full text]
  • Sodium Levulinate As Used in Cosmetics
    Safety Assessment of Levulinic Acid and Sodium Levulinate as Used in Cosmetics Status: Draft Report for Panel Review Release Date: August 21, 2020 Panel Meeting Date: September 14-15, 2020 The Expert Panel for Cosmetic Ingredient Safety members are: Chair, Wilma F. Bergfeld, M.D., F.A.C.P.; Donald V. Belsito, M.D.; Curtis D. Klaassen, Ph.D.; Daniel C. Liebler, Ph.D.; James G. Marks, Jr., M.D.; Lisa A. Peterson, Ph.D.; Ronald C. Shank, Ph.D.; Thomas J. Slaga, Ph.D.; and Paul W. Snyder, D.V.M., Ph.D. The Cosmetic Ingredient Review (CIR) Executive Director is Bart Heldreth, Ph.D. This safety assessment was prepared by Preethi S. Raj, M.Sc., Senior Scientific Analyst/Writer, CIR. © Cosmetic Ingredient Review 1620 L Street, NW, Suite 1200 ♢ Washington, DC 20036-4702 ♢ ph 202.331.0651 ♢ fax 202.331.0088 ♢ [email protected] Distributed for Comment Only -- Do Not Cite or Quote Commitment & Credibility since 1976 Memorandum To: Expert Panel for Cosmetic Ingredient Safety Members and Liaisons From: Preethi S. Raj, M.Sc. Senior Scientific Analyst, CIR Date: August 21, 2020 Subject: Safety Assessment of Levulinic Acid and Sodium Levulinate as Used in Cosmetics Enclosed is the draft report of the Safety Assessment of Levulinic Acid and Sodium Levulinate as Used in Cosmetics (identified as levaci092020rep in the pdf). This is the first time the Panel is seeing a safety assessment of these cosmetic ingredients. A Scientific Literature Review (SLR) was announced on February 21, 2020. Following the announcement of the SLR, two human repeat insult patch tests for Sodium Levulinate were received, and have been included in this report (levaci092020data2): • Essex Testing Clinic, Inc.
    [Show full text]
  • Sodium & Potassium Lactate
    Formal Recommendation From: National Organic Standards Board (NOSB) To: the National Organic Program (NOP) Date: April 27, 2016 Subject: Addition of Sodium Lactate and Potassium Lactate at §205.605(b) - Synthetics allowed. NOSB Chair: Tracy Favre The NOSB hereby recommends to the NOP the following: Rulemaking Action: X Guidance Statement: Other: Statement of the Recommendation: The NOSB classified both sodium lactate and potassium lactate as synthetic, and recommended addition to the National List at §205.605(b) Nonagricultural (nonorganic) substances allowed as ingredients in or on processed products labeled as “organic” or “made with organic (specified ingredients or food group(s))” Synthetics Allowed. Sodium lactate and Potassium lactate as annotated: “for use as an antimicrobial agent and pH regulator only”. Rationale Supporting Recommendation (including consistency with OFPA and Organic Regulations): The NOP received a petition to add these two materials to the National List on January 5, 2004. It was decided at that time that this would not be necessary since the three materials (sodium hydroxide, potassium hydroxide, and lactic acid) used to formulate these two products were already on the National List. On June 25th, 2014 the NOP issued a memorandum to the National Organic Standards Board asking them to once again take up this original petition and review these two materials as petitioned for consideration to be added to the National List. The previous decision by the NOP had resulted in considerable confusion and the NOP felt that a new review was needed for the benefit of organic certifiers and handlers. Since sodium lactate and potassium lactate (along with the three materials that they are derived from) are currently being used in organic handling, they were deemed by the NOSB to be compatible with organic handling principals.
    [Show full text]