CNTNAP2 monoclonal antibody, Storage Instruction: Store at 4°C. clone FF19 (Streptavidin) Aliquot to avoid repeated freezing and thawing.

Entrez GeneID: 26047 Catalog Number: MAB11925

Gene Symbol: CNTNAP2 Regulatory Status: For research use only (RUO)

Gene Alias: AUTS15, CASPR2, CDFE, Product Description: Mouse monoclonal antibody DKFZp781D1846, NRXN4 raised against partial recombinant CNTNAP2.

Gene Summary: This gene encodes a member of the Clone Name: FF19 family which functions in the vertebrate nervous Immunogen: Recombinant fusion corresponding system as cell adhesion molecules and receptors. This to amino acids of 96-1265 at extracellular domain of protein, like other neurexin , contains epidermal human CNTNAP2. growth factor repeats and G domains. In addition, it includes an F5/8 type C domain, Host: Mouse discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative Reactivity: Human,Mouse,Rat PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons and associated with Applications: ICC, IF, IHC, IP, WB potassium channels. It may play a role in the local (See our web site product page for detailed applications differentiation of the axon into distinct functional information) subdomains. This gene encompasses almost 1.5% of 7 and is one of the largest in the Protocols: See our web site at . It may represent a positional candidate http://www.abnova.com/support/protocols.asp or product gene for the DFNB13 form of nonsyndromic deafness. page for detailed protocols [provided by RefSeq]

Specificity: Detects ~180 kDa. No cross reactivity to CASPR/Paranodin.

Form: Liquid

Conjugation: Streptavidin

Purification: Protein G Purification

Isotype: IgG2a

Recommend Usage: Immunocytochemistry (1:100) Immunofluorescence (1:100) Immunohistochemistry (1:1000) Immunoprecipitation Western Blot (1:1000) The optimal working dilution should be determined by the end user.

Storage Buffer: In PBS, pH 7.4 (50% glycerol, 0.09% sodium azide).

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