Signal Transduction Related Molecules Screening Assays 이제 원하는

AntibodyAntibody AArraysrrays

Signal Transduction related molecules Screening Assays 이제 원하는 방법대로 Screening하세요!!! Screening Monitoring 효능평가 실험결과를 극적으 treatment에 대해 Anti-cancer 로 보여줄 수 있는 어떤 protein들이 Anti-obesity target이 뭐가 있지? 변화하지? Anti-angiogenesis Anti-inflammatory

Membrane-based Antibody Arrays Microplate-based Antibody Arrays Fast, Easy, & No specialized equipment for High-throughput Analysis

Screening/ Monitoring/ 효능평가 An array in each well of a 96-well microplate Rapid screening of a large number of analytes Screen for multiple proteins in a single sample The most referenced phospho-Ab arrays Utilizes small sample size High Sensitivity Fast and easy to use Semi-Quantitation Available as predefined or custome arrays

IP-10 TNF-α IL-6 GM-CSF sICAM-1MIP1-α IL-16 IL-1ra RS ErbB3 1 2 3 4 5 6 7 8 9 10 11 12 ErbB2 ErbB4 A B C D RS 140 E Phospho-ErbB2 F

120) Phospho-ErbB3

Untreated 4 Analyte 100 Phospho-ErbB4 60000 IL-16 MIP1-α RS ErbB3 IL-1ra IP-10 Light y 50000 80 Substrate t i ErbB2 ErbB4 s IL-6

n 40000 sICAM-1 e TNF-α 60 D

l 30000 GM-CSF

HRP-conjugated Pan e

x HRP Anti-phospho-tyrosine i 20000 40 P RS Capture Antibody Target Analyte 10000 Multiple Ab Specific Density (x 10 Pixel 20 0 Capture 1 2 3 4 5 6 7 8 9 10 11 12 1 2 3 4 5 6 7 8 9 10 11 12 1 2 3 4 5 6 7 8 9 10 11 12 1 2 3 4 Spotted 96 Well NRG1-β1 0 Array Membrane BCDE Antibody Untreated NRG1-β1

Membrane-based Proteome Profiler Antibody Array List Human Phosphao-RTK Array kit (49 analytes, Cat# ARY001B) ALK, Axl, DDR1, DDR2, Dtk, EGF R, EphA1, EphA2, EphA3, EphA4, EphA5, EphA6, EphA7, EphA10, EphB1, EphB2, EphB3, EphB4, EphB, ErbB2, ErbB3, ErbB4, FGF R1, FGF R2 alpha FGF R3, FGF R4, Flt-3, HGF R, IGF-I R, Insulin R, M-CSF R, Mer, MSP R, MuSK, PDGF R alpha, PDGF R beta, c-Ret, ROR1, ROR2, Ryk, SCF R/c-kit, Tie-1, Tie-2, TrkA, TrkB, TrkC VEGF R1, VEGF R2, VEGF R3 Human Phosphao-MAPK Array kit (26 analytes, Cat# ARY002B) Akt1, Akt2, Akt3, Akt pan, CREB, ERK1, ERK2, GSK-3a/b, GSK-3b, HSP27, JNK`, JNK2, JNK3, JNK pan, MKK3, MKK6, MSK2, p38α, p38β, p38δ, p38γ, p53, p70 S6 kinase, RSK1, RSK2, TOR Membrane-based Proteome Profiler Antibody Array List (continue...) Human Phosphao-Kinase Array kit (43 analytes, Cat# ARY003B) Akt (S473) , Akt (T308), AMPK alpha1 (T174), AMPK alpha2 (T172), beta-Catenin, Chk-2 (T68), c-Jun (S63), CREB (S133), EGF R (Y1068), eNOS (S1177), ERK1/2 (T202/Y204, T185/Y187), FAK (Y397), Fgr (Y412), Fyn (Y420), GSK-3 alpha/beta (S21/S9), Hck (Y411), HSP27 (S78/S82), HSP60, JNK pan (T183/Y185, T221/Y223), Lck (Y394), Lyn (Y397), MSK1/2 (S376/S360), p27 (T198), p38 alpha (T180/Y182), p53 (S15), p53 (S392), p53 (S46), p70 S6 Kinase (T421/S424), PDGF R beta (Y751), PLC gamma-1 (Y783), PRAS40 (T246), Pyk2 (Y402), RSK1/2/3 (S380), Src (Y419), STAT2 (Y689), STAT3 (S727), STAT3 (Y705), STAT5a (Y699), STAT5a/b (Y699), STAT5b (Y699), STAT6 (Y641), TOR (S2448), WNK-1 (T60), Yes (Y426) Human Phosphao-Immunoreceptor Array kit (59 analytes, Cat# ARY004) 2B4/SLAMF4, BLAME/SLAMF8, BTLA, CD3 epsilon, CD5, CD6, CD28, CD84/SLAMF5, CD229/SLAMF3, CEACAM-1, CLEC-1, CLEC-2, CRACC/SLAMF7, CTLA-4/CD152, DCIR/CLEC4A, Dectin-1/CLEC7A, DNAM-1, Fc epsilon RII/CD23, Fc gamma RIIA, Fc gamma RIIIA/B, FcRH1, FcRH2, FcRH4 ,FcRH5, ILT2/CD85j, ILT3/CD85k, ILT4/CD85d, ILT5/CD85a, ILT6/CD85e, Integrin beta 3/CD61, KIR2DL4, LAIR-1, LAIR-2, LMIR1/CD300A, LMIR2/CD300C, LMIR3/CD300LF, LMIR6/CD300LE, MDL-1/CLEC5A, NKp30/NCR3, NKp44/NCR2,NKp46/NCR1, NKp80/KLRF1, NTB-A/SLAMF6, PD-1, PECAM/CD31, SHIP-1, SHP-1, SHP-2, Siglec-2/CD22, Siglec-3/CD33, Siglec-5, Siglec-7, Siglec-9, Siglec-10, SIRP-beta 1, SLAM/CD150, REM-1, TREM-2, TREML1/TLT-1 Human Apoptosis Array kit (35 analytes, Cat# ARY009) Bad, Bax, Bcl-2, Bcl-x, Pro-Caspase-3, Cleaved Caspase-3, Catalase, cIAP-1, cIAP-2, Claspin, Clusterin, Cytochrome c , TRAIL R1/DR4, TRAIL R2/DR5 , FADD, Fas/TNFSF6, HIF-1 alpha, HO-1/HMOX1/HSP32, HO-2/HMOX2, HSP27, HSP60, HSP70, HTRA2/Omi, Livin, PON2, p21/CIP1/CDNK1A, p27/Kip1, Phospho-p53 (S15), Phospho-p53 (S46), Phospho-p53 (S392), Phospho-Rad17 (S635), SMAC/Diablo, Survivin, TNF RI/TNFRSF1A, XIAP Human Pluripotent Stem Cell Array Kit (15 analytes, Cat# Cat# ARY010) alpha-Fetoprotein, Oct-3/4, Nanog, SOX2, E-Cadherin, GATA-4, HNF-3 beta/FoxA2, PDX-1/IPF1, SOX17, Otx2, p63/TP73L, Goosecoid, Snail, VEGF R2/KDR, HCG Mouse Phosphao-RTK Array kit (39 analytes, Cat# ARY014) EGF R,PDGF Ralpha,VEGF R3,ErbB2,PDGF R beta,MuSK,ErbB3,SCF R,EphA1,ErbB4,Flt-3,EphA2,FGF R2 (IIIc),M-CSF R,EphA3,FGF R3,c-Ret,EphA6,FGF R4,Tie-1,EphA7,Insulin R, Tie-2,EphA8, IGF-IR,TrkA,EphB1,Axl,TrkB,EphB2,DtK,TrkC,EphB4,Mer,VEGF R1,EphB6,HGF R,VEGF R2,MSP R Human Cell Stress Array kit (26 analytes, Cat# ARY018) ADAMTS1,HIF-2 alpha,Phospho-p38 alpha (T180/Y182),Bcl-2,Phospho-HSP27 (S78/S82),Phospho-p53 (S46),Carbonic Anhydrase IX,HSP60,PON1,Cited-2,HSP70,PON2,COX-2, IDO,PON3,Cytochrome c,Phospho-JNK Pan (T183/Y185),Thioredoxin-1,Dkk-4,NFkappaB1,SIRT2,FABP1/L-FABP,p21/CIP1,SOD2,HIF-1 alpha,p27/Kip1

Microplate-based Proteome Profiler Antibody Array List Proteome Profiler 96 Human Phosphao-RTK Array 1 (16 plex, Cat# ARZ001) EGF R, ErbB2, ErbB3, ErbB4, HGF R, IGF-I R, INSR, M-CSF R, MSP R, PDGF R alpha, PDGF R beta, SCF R, Tie-2, VEGF R1, VEGF R2, VEGF R3

Proteome Profiler 96 Human Phosphao-RTK Array 2 (8 plex, Cat# ARZ002) Proteome Profiler 96 Human Phosphao-RTK Array 3 (8 plex, Cat# ARZ003) EGF R, EphB4, ErbB2, ErbB3, ErbB4, HGF R, IGF-I R, MSP R EphB4, PDGF R alpha, PDGF R beta, Tie-1, Tie-2, VEGF R1, VEGF R2, VEGF R3

Proteome Profiler 96 Human Phosphao-Kinase Array 1 (7 plex, Cat# ARZ004) Akt (S473), ERK1/ERK2 (T202/Y204), GSK-3 beta (S9), JNK (T183/Y185), p38 alpha (T180/Y182), p70 S6 Kinase (T421/S424), Src (Y416)

Proteome Profiler 96 Human Phospho-RTK Custom Array (3~8 analytes selection, Cat# ARZC001) ALK/CD246,Axl,DDR1,DDR2,Dtk,EGF R/ErbB1,EphA1,EphA10,EphA2,EphA5,EphB2,EphB3,EphB4,ErbB2/Her2,ErbB3/Her3,ErbB4/Her4,FGF R1,FGF R2 alpha,FGF R3,FGF R4, Flt-3/Flk-2,HGF R/c-MET,IGF-I R,Insulin R/CD220,LMTK2,M-CSF R,Mer,MSP R/Ron,PDGF R alpha,PDGF R beta,Ret,Ryk,SCF R/c-kit,Tie-1,Tie-2,TrkA,TrkB,TrkC,VEGF R1/Flt-1, VEGF R2/KDR,VEGF R3/Flt-4 Proteome Profiler 96 Human Phospho-Kinase Custom Array (3~8 analytes selection, Cat# ARZC002) Akt (S473),AMPK alpha 1 (T174),beta-Catenin,CREB (S133),eNOS (S1177),ERK1/ERK2 (T202/Y204, T185/Y187),FAK (Y397),GSK-3 alpha/beta (S21/S9),HSP27 (S78/S82), JNK (T183/Y185, T221/Y223),MKK6 (S207/T211),p27/Kip1 (T198),p38 alpha (T180/Y182),p53 (S15),p53 (S392),p53 (S46),p70 S6 Kinase (T421/S424),PYK2/FAK2 (Y402), Src (Y419),STAT3 (Y705),STAT5b (Y699) Proteome Profiler 96 Mouse Phospho-RTK Custom Array (3~8 analytes selection, Cat# ARZC003) Axl,Dtk,EGF R/ErbB1,EphA1,EphA2,EphA3,EphA4,EphA5,EphA6,EphA8,EphB2,EphB3,EphB4,ErbB2/Her2,ErbB3/Her3, ErbB4/Her4,Flt-3/Flk-2,HGF R/c-MET,IGF-I R,Insulin R/CD220,M-CSF R,PDGF R alpha,PDGF R beta,Tie-1,Tie-2