Rabbit Anti-Human CREB1 (Phospho-Ser129) Polyclonal Antibody (CABT-L3444) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

Rabbit Anti-Human CREB1 (Phospho-Ser129) polyclonal antibody (CABT-L3444) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Product Overview Rabbit Anti-Human GABA-RB (Phospho-Ser434) polyclonal antibody. This antibody detects endogenous levels of CREB only when phosphorylated at Ser129.

Specificity Target Modification: Phospho. Modification Sites: Human: S129; Mouse: S129; Rat: S129

Target Human CREB (Phospho-Ser129)

Immunogen The antiserum was produced against synthesized peptide derived from human CREB around the phosphorylation site of Ser129. Immunogen range: 96-145

Isotype IgG

Source/Host Rabbit

Species Reactivity Human, Mouse, Rat

Purification Affinity Purified

Conjugate Unconjugated

Applications IHC, ELISA

Molecular Weight 36 kDa

Preparation The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Format Liquid

Concentration Lot specific

Buffer Rabbit IgG in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl and 50% glycerol.

Preservative 0.02% Sodium Azide

Storage Stable at -20°C for at least 1 year.

Ship Wet ice

Warnings For research use only.

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Introduction This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms.

Keywords CREB1;cAMP responsive element binding protein 1;CREB;cyclic AMP-responsive element- binding protein 1;CREB-1;transactivator protein;active transcription factor CREB;cAMP-response element-binding protein-1;cAMP-responsive element-binding protein 1;

GENE INFORMATION

Gene Name CREB1 cAMP responsive element binding protein 1 [ Homo sapiens (human) ]

Official Symbol CREB1

Synonyms cAMP responsive element binding protein 1, cAMP-response element binding protein, CREB-1, CREB1

Entrez Gene ID 1385

UniProt ID P16220

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]