Probeset p value Probe Set ID Gene Symbol Gene Title Pathway go biological processgo molecular term functiongo cellular term component term 209682_at 7.26E-06 209682_at CBLB Cas-Br-M (murine)--- ecotropicpositive retroviral regulation transformingsignal of transducer T sequence anergynucleus activity b/// /// NLS-bearing /// calcium ionsubstrate binding import /// protein into nucleus binding /// /// immune protein bindingresponse /// /// zinc signal ion bindingtransduction /// zinc /// ioncell binding surface /// receptor ligase linkedactivity signal /// metal transduction ion binding /// intracellular signaling cascade /// modification-dependent protein catabolic process /// T cell activation /// positive regulation of protein catabolic process /// negative regulation of alpha-beta T cell proliferation /// negative regulation of T cell receptor signaling pathway 201421_s_at 2.96E-05 201421_s_at WDR77 WD repeat domain--- 77 spliceosomal snRNPligand-dependent biogenesisnucleus nuclear /// nucleusreceptor /// transcription cytoplasm coactivator activity 203291_at 3.28E-05 203291_at CNOT4 CCR4-NOT transcription--- complex,transcription subunit /// nucleotide4 modification-dependent bindingnucleus /// ///nucleic nucleus protein acid /// bindingcatabolic cytoplasm /// process RNA /// bindingcytoplasm /// regulation /// protein of transcription binding /// zinc ion binding /// ligase activity /// metal ion binding 202208_s_at 4.78E-05 202208_s_at ARL4C ADP-ribosylation--- factor-like small4C GTPase nucleotidemediated signal bindingintracellular transduction /// GTPase /// nucleusactivity ////// nucleusGTP binding 202600_s_at 4.91E-05 202600_s_at NRIP1 nuclear receptorOvarian_Infertility_Genes1 regulationtranscription of transcription coactivatorhistone deacetylasefrom activity RNA polymerase/// complex transcription /// II nucleuspromoter coactivator /// /// nucleus negative activity ///regulation transcription of transcription corepressor from activity RNA ///polymerase transcription II promoter corepressor /// ovarian activity follicle /// receptor rupture binding /// transcription /// protein ///binding lipid storage/// protein /// androgenbinding /// receptor estrogen signaling receptor pathway binding /// ovulationnuclear hormone /// regulation receptor of transcriptionbinding /// glucocorticoid /// positive regulation receptor binding of transcription, /// histone DNA-dependent deacetylase binding /// positive /// retinoid regulation X receptor of transcription binding /// from androgen RNA polymerase receptor binding II promoter 209205_s_at 5.23E-05 209205_s_at LMO4 LIM domain only--- 4 neural tube closuretranscription /// neural factortranscription tube activity closure factor/// /// protein transcription complex binding /// transcription/// /// transcription protein binding factor from complex/// RNA transcription polymerase factor II promoter binding /// transcription factorfrom RNA binding polymerase /// zinc IIion promoter binding ////// metalregulation ion binding of transcription 214793_at 7.29E-05 214793_at DUSP7 dual specificity--- phosphataseprotein 7 amino phosphoproteinacid dephosphorylationnucleoplasm phosphatase /// /// dephosphorylation activity cytoplasm /// protein/// serine/threonine phosphatase activity /// protein tyrosine phosphatase activity /// protein tyrosine phosphatase activity /// protein tyrosine phosphatase activity /// protein binding /// protein tyrosine/serine/threonine phosphatase activity /// hydrolase activity /// phosphatase activity /// MAP kinase tyrosine/serine/threonine phosphatase activity 210212_x_at 0.00015073 210212_x_at MTCP1NB mature T-cell ---proliferation 1cell neighbor proliferation--- 207871_s_at 0.0001611 207871_s_at ST7 suppression of--- tumorigenicity--- 7 --- membrane /// integral to membrane 219100_at 0.00018351 219100_at OBFC1 oligonucleotide/oligosaccharide-binding------foldnucleic containing acid binding ---1 201929_s_at 0.00021016 201929_s_at PKP4 plakophilin 4 --- cell adhesion ///binding cell adhesion /// proteincell-cell binding junction /// protein/// cell junctionbinding /// desmosome 212013_at 0.0002114 212013_at PXDN peroxidasin homolog--- (Drosophila)immune responseperoxidase /// response activityextracellular to /// oxidative interleukin-1 region stress receptor/// hydrogen antagonist peroxide activity catabolic /// iron process ion binding /// oxidation /// calcium reduction ion binding /// protein binding /// oxidoreductase activity /// heme binding /// metal ion binding 203905_at 0.00022733 203905_at PARN poly(A)-specific--- ribonucleasenuclear-transcribed (deadenylationnucleotide nuclease) mRNA binding catabolicnucleus /// ///magnesiumprocess, nucleus nonsense-mediated /// ion nucleus binding /// /// nucleic decay acid /// /// mRNAbindingnucleolus catabolic /// /// RNA cytoplasm processbinding ////// femalecytoplasmmRNA 3'-UTRgamete /// cytoplasmbinding generation /// nuclease/// RNA modificationactivity /// nuclease activity /// exonuclease activity /// poly(A)-specific ribonuclease activity /// protein binding /// hydrolase activity /// metal ion binding 200759_x_at 0.00023647 200759_x_at NFE2L1 nuclear factor ---(erythroid-derivedtranscription 2)-like 1///DNA regulation binding ///ofnucleus transcription,transcription factorDNA-dependent activity /// /// transcription transcription factor from activity RNA polymerase /// transcription II promoter cofactor /// activity heme biosynthetic /// protein bindingprocess /// /// sequence-specific inflammatory response DNA binding /// anatomical /// protein structure dimerization morphogenesis activity /// regulation of transcription 207128_s_at 0.0002696 207128_s_at ZNF223 zinc finger protein--- 223 transcription ///nucleic regulation acid binding ofintracellular transcription, /// DNA /// binding nucleusDNA-dependent /// /// DNA nucleus binding /// regulation /// zinc ofion transcription binding /// metal ion binding 201498_at 0.0002922 201498_at USP7 ubiquitin specific--- peptidase 7ubiquitin-dependent (herpes virus-associated)cysteine-type protein nucleus endopeptidasecatabolic /// process nucleus activity /// /// protein nucleus/// ubiquitin deubiquitination thiolesterase /// activitymodification-dependent /// ubiquitin-specific protein protease catabolic activity process /// ubiquitin-specific/// interspecies interaction protease activitybetween /// organisms protein binding /// protein C-terminus binding /// peptidase activity /// cysteine-type peptidase activity /// hydrolase activity 211031_s_at 0.00029462 211031_s_at CLIP2 CAP-GLY domain--- containing ---linker proteinprotein 2 bindingcytoplasm /// /// plus-end binding/// microtubule /// microtubule associated complex /// microtubule associated complex /// cytoplasmic microtubule 203164_at 0.00029797 203164_at SLC33A1 solute carrier family--- 33 (acetyl-CoAtransport transporter), /// transportacetyl-CoA member /// transporter cellmembrane death1 activity fraction /// /// endoplasmic reticulum membrane /// integral to plasma membrane /// membrane /// integral to membrane 219077_s_at 0.0003061 219077_s_at WWOX WW domain containing--- oxidoreductaseosteoblast differentiationcatalytic activity ///nucleus induction /// binding /// ofcytoplasm apoptosis /// protein /// /// bindingcytoplasm metabolic /// /// proteinprocess cytoplasm binding /// steroid /// /// mitochondrion oxidoreductasemetabolic process /// activityGolgi /// apparatusnegative /// oxidoreductase regulation /// ofactivity Wnt receptor /// oxidoreductase signaling pathway activity /// /// skeletal protein systemdimerization morphogenesis activity /// /// cofactor oxidation binding reduction /// coenzyme /// oxidation binding reduction 201420_s_at 0.00030762 201420_s_at WDR77 WD repeat domain--- 77 spliceosomal snRNPligand-dependent biogenesisnucleus nuclear /// nucleusreceptor /// transcription cytoplasm coactivator activity 201474_s_at 0.00032774 201474_s_at ITGA3 integrin, alphaIntegrin-mediated_cell_adhesion_KEGG 3 ///receptor subunit cell-matrix activityof VLA-3 integrinadhesion /// receptor) calcium complex /// integrin-mediated ion /// binding integrin /// complex protein signaling binding/// membranepathway /// protein /// integralbinding to membrane 201484_at 0.00033507 201484_at SUPT4H1 suppressor of ---Ty 4 homolog negative1 (S. cerevisiae) regulationtranscription of transcription factornucleus activity from/// nucleus RNA/// protein polymerase /// nucleus binding II /// promoter/// nucleoplasm negative /// transcriptionchromatin remodeling elongation /// factor transcription activity /// /// positive regulation transcription of transcription, elongation DNA-dependent factor activity /// /// regulation positive oftranscription transcription elongation from RNA factor polymerase activity II/// promoter zinc ion ///binding RNA ///elongation metal ion from binding RNA ///polymerase protein heterodimerization II promoter /// regulation activity of transcription /// positive regulation of transcription /// positive regulation of transcription from RNA polymerase II promoter 201158_at 0.00034733 201158_at NMT1 N-myristoyltransferase--- 1 in utero embryoniccatalytic development activitycytoplasm /// /// glycylpeptide N-terminal /// cytosol proteinN-tetradecanoyltransferase lipidation /// N-terminal activity protein /// acyltransferase myristoylation ///activity N-terminal /// transferase protein myristoylation activity /// protein lipoylation 202214_s_at 0.00039681 202214_s_at CUL4B cullin 4B --- DNA repair ///protein ubiquitin-dependent bindingcullin-RING /// ubiquitin protein ubiquitin protein catabolic ligase ligase process complex binding /// response to DNA damage stimulus /// cell cycle /// modification-dependent protein catabolic process 210826_x_at 0.00045808 210826_x_at RAD17 RAD17 homolog--- (S. pombe)DNA replicationnucleotide checkpoint binding ///nucleus DNA /// damage///protein nucleus bindingcheckpoint /// nucleus /// ATP/// ///DNAbinding nucleolus repair /// ///nucleoside-triphosphatase /// DNA cytoplasm repair /// response activity to DNA damage stimulus /// response to DNA damage stimulus /// cell cycle /// mitotic cell cycle checkpoint /// negative regulation of DNA replication /// regulation of phosphorylation 218951_s_at 0.00052783 218951_s_at PLCXD1 phosphatidylinositol-specific--- lipid phospholipase metabolicphospholipase processC, X domain /// intracellular--- Ccontaining activity /// signaling1 phosphoric cascade diester hydrolase activity 222244_s_at 0.00053528 222244_s_at TUG1 taurine upregulated--- 1 (non-protein--- coding)------207163_s_at 0.00054276 207163_s_at AKT1 v-akt murine thymomaIntegrin-mediated_cell_adhesion_KEGG homolognucleotide into nucleus, 1 binding solubletranslocation /// fraction protein /// ///kinase blood nucleus activityvessel /// development nucleus/// protein /// kinasenucleoplasm /// placenta activity /// development /// cytoplasm protein serine/threonine ////// cytoplasmcarbohydrate /// kinase metaboliccytoplasm activity process/// /// spindle protein /// glycogen/// serine/threonine cytosol metabolic /// cytoskeleton kinaseprocess activity ////// plasma///glycogen ///S1P_Signaling membrane/// kinase regulation activity /// ofplasma /// glycogen protein membrane biosynthetic serine/threonine /// membrane process kinase /// /// glucoseactivity metabolic/// protein process binding /// /// regulation protein binding of translation /// ATP ///binding protein /// modificationATP binding ///process phosphatidylinositol-3,4,5-trisphosphate /// protein amino acid phosphorylation binding /// protein /// kinase amino activity acid phosphorylation /// kinase activity /// /// negative transferase regulation activity of ///protein enzyme kinase binding activity /// ///enzyme negative binding regulation /// nitric-oxide of protein synthase kinase activity regulator /// activitynegative /// regulation identical proteinof protein binding kinase /// activity phosphatidylinositol-3,4-bisphosphate /// nitric oxide biosynthetic process binding /// transport /// apoptosis /// anti-apoptosis /// activation-induced cell death of T cells /// inflammatory response /// signal transduction /// signal transduction /// G-protein coupled receptor protein signaling pathway /// intracellular signaling cascade /// germ cell development /// insulin receptor signaling pathway /// activation of pro-apoptotic gene products /// apoptotic mitochondrial changes /// carbohy 218307_at 0.00054477 218307_at RSAD1 radical S-adenosyl--- methionineporphyrin domain biosynthetic containingcatalytic 1activityprocesscytoplasm ////// coproporphyrinogenoxidation /// mitochondrion reduction oxidase activity /// iron ion binding /// oxidoreductase activity /// metal ion binding /// iron-sulfur cluster binding /// 4 iron, 4 sulfur cluster binding 218819_at 0.00066048 218819_at INTS6 integrator complex--- subunit 6snRNA processingtransmembranenucleus receptor /// activitynucleus ////// proteinnucleolus binding /// cytoskeleton /// integrator complex 203016_s_at 0.00070435 203016_s_at SSX2IP synovial sarcoma,--- X breakpointcell adhesion2 interactingprotein protein bindingnucleus /// protein /// adherens binding ///junction actinin /// binding cell-cell adherens junction /// cell junction /// protein complex 210861_s_at 0.00073179 210861_s_at WISP3 WNT1 inducible--- signaling pathwayregulation protein of cellinsulin-like 3 growth ///growth extracellularsignal factor transduction binding region ////// growthsolublecell-cell factorfraction signaling activity 218095_s_at 0.00078461 218095_s_at TMEM165 transmembrane--- protein 165------membrane /// integral to membrane 201778_s_at 0.00084222 201778_s_at KIAA0494 KIAA0494 ------calcium ion binding--- 209931_s_at 0.00089085 209931_s_at FKBP1B /// MFSD2BFK506 binding--- protein 1B, 12.6regulation kDa /// of major heartpeptidyl-prolyl facilitatorrate /// proteincytoplasm superfamilycis-trans folding isomerase/// domain-containing cytosol/// 'de activitynovo'/// membrane protein /// peptidyl-prolylprotein folding /// integral2b /// transport cis-transto membrane /// isomerase muscle /// sarcoplasmic contractionactivity /// ///receptorreticulum smooth binding membrane muscle /// contraction ryanodine-sensitive /// calcium /// channel response calcium-release complex to glucose stimulus channel /// activity negative /// regulationprotein binding of heart /// rateprotein /// bindingnegative /// regulation FK506 binding of heart /// rate FK506 /// regulationbinding /// of isomerase cardiac muscle activity contraction by regulation of the release of sequestered calcium ion /// regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion /// release of sequestered calcium ion into cytosol by sarcoplasmic reticulum /// neuronal action potential propagation /// protein maturation by protein folding /// insulin secretion /// regulation of calcium ion transport via store-operated calcium channel activity /// negative regulation of protein phosphatase type 2B activity /// protein refolding /// T cell proliferation /// release of sequestered calcium ion into cytosol /// response to redox state /// regulation of ryanodine-sensitive calcium-release channel activity /// regulation of ryanodine-sensitive cal 200758_s_at 0.00091056 200758_s_at NFE2L1 nuclear factor ---(erythroid-derivedtranscription 2)-like 1///DNA regulation binding ///ofnucleus transcription,transcription factorDNA-dependent activity /// /// transcription transcription factor from activity RNA polymerase /// transcription II promoter cofactor /// activity heme biosynthetic /// protein bindingprocess /// /// sequence-specific inflammatory response DNA binding /// anatomical /// protein structure dimerization morphogenesis activity /// regulation of transcription 219206_x_at 0.00096111 219206_x_at TMBIM4 transmembrane--- BAX inhibitor--- motif containingprotein 4 bindingmembrane /// integral to membrane 221874_at 0.00098486 221874_at KIAA1324 KIAA1324 ------protein bindingmembrane /// integral to membrane 201353_s_at 0.00100233 201353_s_at BAZ2A bromodomain ---adjacent to zincchromatin finger domain, silencingDNA 2Abinding at rDNA ///nucleus /// DNA DNA binding/// methylation chromatin /// RNA ///silencing binding chromatin complex/// RNAremodeling binding/// nucleolus ////// transcriptionprotein /// nucleolus binding /// ///regulation nucleolusprotein ofbinding organizertranscription, /// zinc region ionDNA-dependent ///binding rDNA ///heterochromatin transcription /// chromatin regulator modification activity /// /// histone metal deacetylationion binding /// /// histone regulation acetyl-lysine of transcription binding 212435_at 0.0010082 212435_at TRIM33 tripartite motif-containing--- 33transcription ///DNA negative binding regulation ///intracellular protein of binding transcription /// nucleus /// protein ////// nucleusprotein binding ///ubiquitination /// intracellular zinc ion binding /// membrane-bounded regulation /// zinc of ion transforming binding /// growthligase activity factor beta/// metal receptor ion bindingsignaling /// pathway co-SMAD /// binding modification-dependent /// R-SMAD binding protein catabolic process /// negative regulation of BMP signaling pathway /// regulation of transcription 217921_at 0.0010093 217921_at MAN1A2 mannosidase, ---alpha, class 1A,N-glycan member processing 2 mannosyl-oligosaccharide /// respiratoryGolgi membrane gaseous 1,2-alpha-mannosidase exchange/// membrane /// metabolic fraction activity ///process Golgi /// mannosyl-oligosaccharide ///apparatus glycoprotein /// membrane metabolic 1,2-alpha-mannosidase ///process integral /// tolung membrane alveolus activity ///development integral /// calcium to membrane ion binding /// hydrolase activity /// hydrolase activity, acting on glycosyl bonds 213229_at 0.00101387 213229_at DICER1 dicer 1, ribonucleasemRNA_processing_Reactome ///nucleotide RNA processing bindingintracellular ////// magnesiumstem /// cell cytoplasm maintenance ion binding /// RNA-induced ////// lungnucleic development acidsilencing binding complex /// /// embryonic RNA binding limb ///morphogenesis double-stranded /// RNARNA interference,binding /// double-stranded production of siRNA RNA ///binding RNA ///interference, helicase activity targeting /// ofnuclease mRNA foractivity destruction /// endonuclease /// gene silencing activity by/// RNAribonuclease /// pre-microRNA III activity processing /// ribonuclease /// embryonic III activity hindlimb /// protein morphogenesis binding /// /// ATP gene binding silencing /// ATP-dependent by miRNA, production helicase of activity miRNAs /// /// hydrolase branching activity morphogenesis /// manganese of a tube ion binding /// metal ion binding 205340_at 0.00101513 205340_at ZBTB24 zinc finger and--- BTB domain transcriptioncontaining 24 ///nucleic regulation acid binding ofintracellular transcription /// DNA /// binding nucleus /// protein binding /// protein binding /// zinc ion binding /// metal ion binding 218665_at 0.00101615 218665_at FZD4 frizzled homolog--- 4 (Drosophila)signal transductionsignal /// transducer cell surfacemembrane activity receptor ////// integralreceptor linked signalto activity membrane transduction /// transmembrane /// integral /// G-protein to membranereceptor coupled activity receptor /// non-G-protein protein signaling coupled pathway 7TM ///receptor multicellular activity organismal /// G-protein development coupled receptor /// Wnt activity receptor /// signaling protein binding pathway /// Wnt-protein binding /// Wnt receptor activity 207270_x_at 0.00102491 207270_x_at CD300C CD300c molecule--- immune responsereceptor /// cellular activityplasma defense /// transmembrane membrane response /// integralreceptor to activity plasma membrane /// membrane /// integral to membrane 203679_at 0.00102514 203679_at TMED1 transmembrane--- emp24 proteintransport transport /// signaldomainreceptor transduction containing bindingplasma /// ///1 protein membranecell-cell binding signaling /// membrane /// integral to membrane 205512_s_at 0.00108723 205512_s_at AIFM1 apoptosis-inducing--- factor, mitochondrion-associated,DNA fragmentationDNA binding involved 1 ///soluble in protein apoptosis fraction binding /// /// DNA /// nucleus electronfragmentation /// carriernucleus involvedactivity /// cytoplasm ///in apoptosiselectron /// mitochondrion carrier /// apoptosis activity /// ////// mitochondrion DNAoxidoreductase damage response, /// activity mitochondrial signal/// FAD transduction intermembranebinding resulting space in /// induction of apoptosis /// apoptotic chromosome condensation /// cell redox homeostasis /// neuron apoptosis /// oxidation reduction 201776_s_at 0.00110892 201776_s_at KIAA0494 KIAA0494 ------calcium ion binding--- 213325_at 0.00113717 213325_at PVRL3 poliovirus receptor-related--- 3lens morphogenesisreceptor in activitycamera-typeplasma /// protein membraneeye /// binding cell /// adhesion ///plasma protein /// membrane homophilicbinding ////// cellproteincell-cell adhesion homodimerization junction /// homophilic/// cell-cell activity cell adherens adhesion /// protein junction /// fertilizationhomodimerization /// membrane /// cell-cell /// activity integral adhesion /// to /// adhesion retina /// morphogenesismolecule apical junctionbinding in camera-typecomplex eye 216862_s_at 0.00120157 216862_s_at MTCP1NB mature T-cell ---proliferation 1cell neighbor proliferation--- mitochondrion 221819_at 0.00122436 221819_at RAB35 RAB35, member--- RAS oncogenecytokinesis family ///nucleotide transport binding/// plasmasmall /// GTPase membraneGTPase mediated activity /// plasma signal/// GTP membranetransduction binding /// /// phosphatidylinositol-4,5-bisphosphate/// coated protein pit localization/// membrane /// protein/// cell projectiontransport binding ///membrane /// transport melanosome /// intercellular bridge /// clathrin-coated endocytic vesicle 212436_at 0.00123183 212436_at TRIM33 tripartite motif-containing--- 33transcription ///DNA negative binding regulation ///intracellular protein of binding transcription /// nucleus /// protein ////// nucleusprotein binding ///ubiquitination /// intracellular zinc ion binding /// membrane-bounded regulation /// zinc of ion transforming binding organelle /// growthligase activity factor beta/// metal receptor ion bindingsignaling /// pathway co-SMAD /// binding modification-dependent /// R-SMAD binding protein catabolic process /// negative regulation of BMP signaling pathway /// regulation of transcription 218103_at 0.00132475 218103_at FTSJ3 FtsJ homolog 3--- (E. coli) rRNA processingnucleic /// rRNA acid methylationbindingnucleus /// /// methyltransferase /// nucleolus methylation activity /// transferase activity 200659_s_at 0.00133889 200659_s_at PHB prohibitin --- DNA replicationprotein /// signal binding transductionnucleus /// transcription /// ///nucleoplasm negative activator regulation /// activitymitochondrion of /// cell transcription proliferation /// mitochondrion repressor /// negative /// activity mitochondrial regulation of inner transcription membrane /// ///histone mitochondrial deacetylation inner /// membrane regulation /// of integral apoptosis to ///plasma regulation membrane of transcription /// membrane 220208_at 0.00133933 220208_at ADAMTS13 ADAM metallopeptidase--- withproteolysis thrombospondin ///endopeptidase proteolysis type 1 motif, ///extracellular activitycell-matrix 13 /// metalloendopeptidaseregionadhesion /// ///proteinaceous integrin-mediated activity extracellular /// signaling integrin matrix pathwaybinding /// proteinaceous ////// calciumblood coagulation ion extracellular binding /// /// hemostasis matrixcalcium /// ion extracellular /// binding glycoprotein /// spaceprotein metabolic /// binding cell surface process /// peptidase /// protein activity processing /// metallopeptidase /// platelet activation activity /// metallopeptidasepeptide catabolic processactivity /// zinc ion binding /// zinc ion binding /// hydrolase activity /// metal ion binding 202511_s_at 0.00134588 202511_s_at ATG5 ATG5 --- related 5 homologautophagic (S. vacuolecerevisiae)protein formation bindingcytoplasm ////// proteinautophagic /// binding cytoplasm /// formation autophagic /// bloodvacuole vessel /// autophagicremodeling vacuole /// autophagy /// pre-autophagosomal /// autophagy /// structureapoptosis membrane /// negative /// regulation pre-autophagosomal of protein ubiquitination structure membrane /// vasodilation /// intracellular /// response membrane-bounded to drug /// negative organelle regulation of apoptosis /// post-translational protein modification /// post-translational protein modification /// ventricular cardiac muscle cell development /// heart contraction 205013_s_at 0.00139343 205013_s_at ADORA2A /// CYTSAadenosine A2aGPCRDB_Class_A_Rhodopsin-like Atransmission,adenosine dopaminergic receptormembrane activity, /// fraction adenosine G-protein /// membranereceptor coupled signaling/// fraction signal pathway ///transducer intermediate /// activityresponse filament /// to receptor amphetamine /// plasma activity membrane /// /// cAMP G-protein biosynthetic/// plasma coupled membrane process receptor /// activity/// regulation integral /// protein toof plasma///transcription, Nucleotide_GPCRs /// peptidenegative density receptor regulation/// membrane activity of protein /// typeintegral kinase 5 metabotropic to activity membrane /// glutamateneurotransmitter /// axon ///receptor dendrite transport binding /// axolemma /// phagocytosisprotein /// heterodimerization asymmetric /// apoptosis synapse ///activity inflammatory/// presynaptic /// nonmuscle response membrane alpha-actinin /// cellular/// cell binding somadefense /// response postsynaptic /// cell membrane cycle /// ///signal presynaptic transduction active /// zone transmembrane receptor protein tyrosine kinase signaling pathway /// G-protein coupled receptor protein signaling pathway /// G-protein signaling, coupled to cAMP nucleotide second messenger /// activation of adenylate cyclase activity by G-protein signaling pathway /// activation of adenylate cyclase activity /// activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway /// cell-cell signaling /// synaptic transmission, cholinergic /// central nervous system development /// blood coagulation /// sensory perception /// locomotory behavior /// blood circulation /// negative regulation o 212337_at 0.00141404 212337_at TUG1 taurine upregulated--- 1 (non-protein--- coding)------202207_at 0.00145064 202207_at ARL4C ADP-ribosylation--- factor-like small4C GTPase nucleotidemediated signal bindingintracellular transduction /// GTPase /// nucleusactivity ////// nucleusGTP binding 202522_at 0.00147388 202522_at PITPNB phosphatidylinositol--- transferin protein, utero embryonic betalipid binding developmentintracellular /// lipid /// metabolic nucleus process/// cytoplasm /// transport /// cytoplasm /// Golgi apparatus /// intracellular membrane-bounded organelle 202290_at 0.00149004 202290_at PDAP1 PDGFA associated--- protein 1signal transduction--- /// cell proliferation--- 222114_x_at 0.00149104 222114_x_at WDR55 WD repeat domain--- 55 rRNA processing--- /// rRNA processingnucleus /// nucleolus /// nucleolus /// cytoplasm 200861_at 0.00155092 200861_at CNOT1 CCR4-NOT transcription--- complex,transcription subunit /// ---1 regulation of--- transcription 204136_at 0.00158439 204136_at COL7A1 collagen, type--- VII, alpha 1 cAMP biosyntheticG-protein-coupled process ///extracellular response receptor to region binding stress /// ////// extracellular cellserine-type adhesion region endopeptidase /// digestion /// proteinaceous /// inhibitor cell proliferation extracellularactivity /// /// receptor matrixepidermis ///binding collagendevelopment /// hormone type VII ///activity basement /// protein membrane binding /// /// basement protein binding membrane /// peptidase inhibitor activity /// hormone binding 204622_x_at 0.00162295 204622_x_at NR4A2 nuclear receptorNuclear_Receptors A, to member hypoxiaDNA binding 2/// neuron ///nucleus DNA migration binding/// nucleus /// /// response transcription /// cytoplasm to amphetamine factor activity /// /// transcription steroid hormone /// regulation receptor of activity transcription, /// receptor DNA-dependent activity /// ligand-dependent/// induction of apoptosis nuclear receptor/// response activity to stress /// ligand-dependent /// signal transduction nuclear /// receptor signal activitytransduction /// protein /// nervous binding system /// protein development binding /// zincadult ion locomotory binding /// behavior transcription /// post-embryonic activator activity development /// transcription /// response regulator to inorganic activity /// substance protein homodimerization/// gene expression activity /// death /// sequence-specific/// response to insecticide DNA binding /// central /// metal nervous ion binding system /// projection protein heterodimerization neuron axonogenesis activity /// central nervous system neuron differentiation /// neuron differentiation /// cellular response to extracellular stimulus /// cellular response to extracellular stimulus /// regulation of dopamine metabolic process /// dopamine biosynthetic process /// dopamine metabolic process /// neuron maturation /// positive regulation of catalytic activity /// negative regulation of caspase activity /// negative regulation of neuron apoptosis /// regulation of respiratory gaseous exchange /// regulation of transcription /// positive regulation of tra 202512_s_at 0.00164019 202512_s_at ATG5 ATG5 autophagy--- related 5 homologautophagic (S. vacuolecerevisiae)protein formation bindingcytoplasm ////// proteinautophagic /// binding cytoplasm vacuole /// formation autophagic /// bloodvacuole vessel /// autophagicremodeling vacuole /// autophagy /// pre-autophagosomal /// autophagy /// structureapoptosis membrane /// negative /// regulation pre-autophagosomal of protein ubiquitination structure membrane /// vasodilation /// intracellular /// response membrane-bounded to drug /// negative organelle regulation of apoptosis /// post-translational protein modification /// post-translational protein modification /// ventricular cardiac muscle cell development /// heart contraction 200969_at 0.00166691 200969_at SERP1 stress-associated--- endoplasmicskeletal reticulum system protein--- development 1 endoplasmic /// glucose reticulummetabolic ///process endoplasmic /// protein reticulum modification /// process /// /// membrane protein amino /// integral acid glycosylation to membrane /// transport /// response to stress /// plasma membrane organization /// post-embryonic development /// multicellular organismal aging /// protein transport /// endoplasmic reticulum unfolded protein response /// positive regulation of insulin secretion /// positive regulation of translation /// positive regulation of organ growth /// muscle organ morphogenesis /// transmembrane transport /// positive regulation of growth hormone secretion /// intracellular protein transmembrane transport 220191_at 0.00170077 220191_at GKN1 gastrokine 1 --- digestion /// positivegrowth factorregulation extracellularactivity of cell proliferation region /// secretory/// positive regulation of cell division 220212_s_at 0.00176531 220212_s_at THADA thyroid adenoma--- associated--- receptor activity--- /// binding 218740_s_at 0.00185041 218740_s_at CDK5RAP3 CDK5 regulatory--- subunit associatedregulation protein of cyclin-dependentprotein 3 binding--- /// protein neuronal kinase Cdc2-like activity kinase /// brain binding development /// regulation of neuron differentiation 204928_s_at 0.00185377 204928_s_at SLC10A3 solute carrier family--- 10 (sodium/biletransport acid/// sodium bilecotransporter acid:sodium ion transport membranefamily), symporter /// member sodium /// activity integral 3ion transport/// to bilemembrane acid:sodium /// organic /// integral symporter anion totransport membrane activity /// /// response symporter to retinoicactivity acid /// response to chemical stimulus 202850_at 0.0018788 202850_at ABCD3 ATP-binding cassette,--- sub-familytransport D (ALD), /// peroxisomenucleotide member 3 bindingorganizationmitochondrion /// protein /// peroxisomal /// binding mitochondrial /// long-chain protein inner binding fattymembrane acid/// ATP import /// binding /// response /// ATPase /// toperoxisome activitydrug /// /// transmembrane /// nucleoside-triphosphatase peroxisomal transport membrane ///activity peroxisomal /// ATPase membrane activity, ///coupled integral to transmembraneto peroxisomal membrane movement /// of substancesmembrane ////// integralATPase activity,to membrane coupled to transmembrane movement of substances /// protein self-association 209294_x_at 0.00188457 209294_x_at TNFRSF10B tumor necrosisApoptosis /// apoptosisreceptor member activity /// 10b activationplasma /// receptor membrane of caspase activity /// activity membrane/// protein /// signal ///binding integral transduction /// toprotein membrane /// binding cell surface/// /// integral protein receptor to binding membrane linked /// signal caspase transduction activator activity/// activation /// TRAIL of NF-kappaB-inducing binding kinase activity /// induction of apoptosis via death domain receptors /// activation of pro-apoptotic gene products /// regulation of apoptosis /// positive regulation of I-kappaB kinase/NF-kappaB cascade 208093_s_at 0.00191492 208093_s_at NDEL1 nudE nuclear distribution--- genemicrotubule E homolog cytoskeletonprotein (A. nidulans)-like binding organizationkinetochore /// 1protein /// /// binding neuron condensed /// migration microtubule chromosome /// inner binding kinetochore cell ///mass alpha-tubulin cell /// proliferation nuclear binding envelope /// /// transport ///beta-tubulin cytoplasm /// chromosome binding /// /// segregationoligopeptidase /// spindle /// activitymulticellular /// cytoskeleton organismal /// microtubule development /// microtubule /// nervous associated system development complex /// /// axon retrograde /// cell leadingaxon cargo edge transport /// neurofilament /// cell migration cytoskeleton /// central nervous system neuron axonogenesis /// cell differentiation /// neuron projection development /// activation of Cdc42 GTPase activity /// vesicle transport along microtubule /// positive regulation of axon regeneration /// nuclear envelope disassembly /// centrosome localization /// neurofilament cytoskeleton organization 206877_at 0.00198677 206877_at MXD1 MAX dimerization--- protein 1 transcription ///DNA multicellular binding ///nucleus organismal transcription /// nucleus development factor activity /// ///cell transcription proliferation cofactor/// regulation activity of ///transcription transcription corepressor activity /// protein binding /// transcription regulator activity 221031_s_at 0.0020102 221031_s_at APOLD1 apolipoprotein--- L domain containingangiogenesis 1 ///lipid response binding toextracellular hypoxia /// regionlipid transport /// plasma /// membranemulticellular /// organismal membrane development /// integral to/// membrane cell differentiation /// endothelial cell activation /// lipoprotein metabolic process /// regulation of endothelial cell differentiation 221196_x_at 0.00207922 221196_x_at BRCC3 BRCA1/BRCA2-containing--- complex,DNA repair subunit ///ubiquitin double-strand 3 thiolesteraseubiquitin break repair activityligase /// complex /// response ubiquitin /// tonuclear thiolesteraseDNA damage ubiquitin activity stimulus ligase /// complex /// ubiquitin-specific response /// nucleus to DNA protease/// damage nucleus activity stimulus /// BRCA1-A /// /// protein response complex binding to ///X-ray /// BRISC peptidase /// responsecomplex activity to ionizing /// metallopeptidase radiation /// chromatin activity /// modification metallopeptidase /// modification-dependent activity /// zinc ion binding protein /// catabolic hydrolase process activity /// ///G2/M enzyme transition regulator DNA activitydamage /// checkpoint polyubiquitin /// positive binding regulation /// metal ionof DNA binding repair /// protein K63-linked deubiquitination /// histone H2A K63-linked deubiquitination /// histone H2A K63-linked deubiquitination 202776_at 0.0020801 202776_at DNTTIP2 deoxynucleotidyltransferase,--- transcription terminal, interacting ///receptor regulation proteinactivity ofnucleus transcription2 207656_s_at 0.00209884 207656_s_at ACOX1 acyl-Coenzyme--- A oxidase 1,generation palmitoyl of acyl-CoAprecursor dehydrogenasemetabolitescytoplasm and ///activity energy mitochondrion /// /// acyl-CoA lipid metabolic/// oxidaseperoxisome process activity /// /// peroxisome/// lipid acyl-CoA metabolic /// oxidase peroxisomal process activity /// membrane fatty/// acyl-CoA acid metabolic oxidase process activity ////// fattyelectron acid carrier beta-oxidation activity /// /// oxidoreductase prostaglandin metabolicactivity /// process oxidoreductase /// spermatogenesis activity, acting /// metabolicon the CH-CH process group /// of fatty donors acid /// oxidation protein ///N-terminus oxidation binding reduction /// FAD binding 201944_at 0.00210789 201944_at HEXB hexosaminidase--- B (beta polypeptide)skeletal systemcatalytic development activityacrosomal /// /// carbohydrate hydrolase vesicle activity, /// metabolic soluble hydrolyzing fractionprocess ///O-glycosyl lysosomeN-acetylglucosamine compounds /// membrane /// metabolic beta-N-acetylhexosaminidase process /// glycosphingolipid activity metabolic/// beta-N-acetylhexosaminidase process /// ganglioside activitycatabolic /// process sugar binding/// cellular /// beta-N-acetylglucosaminidasecalcium ion homeostasis /// activity organization/// hydrolase /// activity single /// fertilization hydrolase /// activity, penetration acting of on zona glycosyl pellucida bonds /// /// sensory protein perception homodimerization of sound activity /// locomotory /// protein behavior homodimerization /// male courtship activity behavior /// cation /// binding metabolic /// processprotein heterodimerization/// phospholipid biosynthetic activity /// process protein ///heterodimerization oligosaccharide catabolicactivity process /// lipid storage /// sexual reproduction /// glycosaminoglycan metabolic process /// regulation of cellular metabolic process /// myelination /// cellular protein metabolic process /// oogenesis /// neuromuscular process controlling balance /// neuromuscular process 207701_at 0.00213795 207701_at C22orf24 chromosome 22--- open reading--- frame 24 --- membrane /// integral to membrane 222256_s_at 0.00214398 222256_s_at JMJD7 /// JMJD7-PLA2G4Bjumonji domain--- containing 7metabolic /// JMJD7-PLA2G4B processphospholipase /// readthroughphospholipid--- activity transcriptcatabolic process 206572_x_at 0.00216894 206572_x_at ZNF85 zinc finger protein--- 85 transcription ///nucleic regulation acid binding ofintracellular transcription, /// DNA /// binding nucleusDNA-dependent /// /// DNA nucleus binding /// regulation /// transcription of transcription factor activity /// transcription corepressor activity /// zinc ion binding /// metal ion binding 200670_at 0.00228585 200670_at XBP1 X-box binding--- protein 1 transcription ///DNA regulation binding ///ofnucleus transcription,DNA binding/// nucleus ///DNA-dependent transcription factor/// immune activity response /// transcription /// regulation factor of activity transcription /// sequence-specific DNA binding /// protein dimerization activity 202484_s_at 0.0023178 202484_s_at MBD2 methyl-CpG binding--- domainnegative protein 2regulationDNA binding of transcription ///histone chromatin deacetylasefrom bindingRNA polymerase complex /// satellite /// II chromatinpromoterDNA binding /// /// transcription ///heterochromatin mRNA binding /// negative /// /// nucleus protein regulation ///binding nucleus of /// transcription ///methyl-CpG nucleus ////// binding positivenucleus /// regulation/// methyl-CpG cytoplasm of Wntbinding receptor /// transcription signaling pathway repressor /// activityregulation /// proteinof cell proliferation domain specific /// maternal binding ///behavior siRNA ///binding cellular /// proteinC2H2 zinc complex finger assemblydomain binding /// regulation of transcription 210876_at 0.00237203 210876_at ANXA2P1 annexin A2 pseudogene--- 1 ------208383_s_at 0.00242953 208383_s_at PCK1 phosphoenolpyruvateGlycolysis_and_Gluconeogenesismetabolic 1 (soluble)nucleotide process binding ///soluble gluconeogenesis /// fraction magnesium /// nucleus/// ion gluconeogenesis binding /// nucleolus /// phosphoenolpyruvate /// /// oxaloacetate cytoplasm /// metabolic carboxykinasecytoplasm process /// cytoplasmactivity /// lipid /// metabolic ///phosphoenolpyruvate centrosome process /// /// cytosol response carboxykinase to insulin (GTP) stimulus activity /// /// glucose phosphoenolpyruvate homeostasis /// carboxykinase glucose homeostasis (GTP) activity /// glycerol /// phosphoenolpyruvate biosynthetic process carboxykinasefrom pyruvate ///(GTP) glycerol activity biosynthetic /// GTP binding process /// from GTP pyruvatebinding /// kinase activity /// lyase activity /// carboxy-lyase activity /// purine nucleotide binding /// GDP binding /// manganese ion binding /// manganese ion binding /// carboxylic acid binding /// carboxylic acid binding /// metal ion binding 210407_at 0.00245933 210407_at PPM1A protein phosphatase--- 1A (formerlyprotein 2C), amino magnesium-dependent, magnesiumacid dephosphorylation ionmembrane binding alpha ////// fraction catalyticWntisoform receptor /// activityvoltage-gated signaling /// phosphoprotein pathwaycalcium channel/// dephosphorylationphosphatase complex ///activity protein /// /// positive serine/threonineprotein regulation serine/threonine ofphosphatase Wnt receptor phosphatase complex signaling activity /// neuronpathway /// proteinprojection /// positive serine/threonine regulation ofphosphatase I-kappaB kinase/NF-kappaB activity /// protein cascade serine/threonine /// positive phosphatase regulation ofactivity transcription, /// signal DNA-dependent transducer activity /// protein binding /// protein C-terminus binding /// hydrolase activity /// manganese ion binding /// metal ion binding 217312_s_at 0.00253221 217312_s_at COL7A1 collagen, type--- VII, alpha 1 cAMP biosyntheticG-protein-coupled process ///extracellular response receptor to region binding stress /// ////// extracellular cellserine-type adhesion region endopeptidase /// digestion /// proteinaceous /// inhibitor cell proliferation extracellularactivity /// /// receptor matrixepidermis ///binding collagendevelopment /// hormone type VII ///activity basement /// protein membrane binding /// /// basement protein binding membrane /// peptidase inhibitor activity /// hormone binding 212645_x_at 0.00257842 212645_x_at BRE brain and reproductive--- organ-expressedDNA repair /// (TNFRSF1Aperoxisome double-strand modulator) targetingnuclear break ubiquitinsequencerepair /// ligaseapoptosisbinding complex /// /// tumor response /// necrosisnucleus to DNA ///factor nucleus damage receptor /// stimulus cytoplasm binding /// /// response/// protein cytoplasm bindingto DNA /// damage///BRCA1-A polyubiquitin stimulus complex binding/// /// signal BRISC transduction complex /// response to ionizing radiation /// chromatin modification /// G2/M transition DNA damage checkpoint /// positive regulation of DNA repair /// positive regulation of anti-apoptosis 202939_at 0.00260985 202939_at ZMPSTE24 zinc metallopeptidase--- (STE24proteolysis homolog, /// S.metalloendopeptidase proteolysiscerevisiae) ///membrane nuclear activity envelope fraction /// organization///peptidase cytoplasm activity /// /// prenylated endoplasmic /// metalloexopeptidase protein reticulum catabolic /// activity Golgiprocess apparatus /// metallopeptidase /// Golgi apparatus activity /// zincmembrane ion binding /// integral /// hydrolase to membrane activity /// metal ion binding 201455_s_at 0.00261042 201455_s_at NPEPPS aminopeptidase--- puromycin sensitiveproteolysis aminopeptidasenucleus activity /// /// cytoplasm aminopeptidase /// cytosol activity /// protein binding /// peptidase activity /// metallopeptidase activity /// zinc ion binding /// hydrolase activity /// metal ion binding 212564_at 0.00263664 212564_at KCTD2 potassium channel--- tetramerisationpotassium domain ionvoltage-gated transport containing 2 voltage-gatedpotassium channel potassium activity channel /// protein complex binding /// membrane 215804_at 0.00264696 215804_at EPHA1 EPH receptor A1--- protein amino nucleotideacid phosphorylation bindingintegral /// ///toprotein plasmasignal kinase transductionmembrane activity /// /// integral transmembraneprotein totyrosine plasma kinasereceptor membrane activity protein /// /// membranetyrosine transmembrane kinase /// integral signaling receptor to membranepathway protein ///tyrosine ephrin kinase receptor activity signaling /// transmembrane pathway receptor protein tyrosine kinase activity /// receptor activity /// ephrin receptor activity /// protein binding /// ATP binding /// kinase activity /// transferase activity 201004_at 0.00267522 201004_at SSR4 signal sequence--- receptor, deltaintracellular (translocon-associated proteinreceptor transport activity proteinendoplasmic /// calcium delta) reticulum ion binding /// ///translocon protein bindingcomplex /// membrane /// integral to membrane 214036_at 0.00268232 214036_at EFNA5 ephrin-A5 --- cell-cell signalingprotein /// multicellularbindingextracellular /// protein organismal spacebinding development /// /// plasma chemorepellent membrane /// nervous activity /// system membrane /// developmentephrin /// receptor anchored /// bindingnervous to membrane /// system ephrin /// development receptor anchored binding to /// plasma axon guidancemembrane /// brain development /// cell differentiation /// retinal ganglion cell axon guidance 202607_at 0.0027185 202607_at NDST1 N-deacetylase/N-sulfotransferase--- MAPKKK (heparan cascadecatalytic glucosaminyl) /// polysaccharide activityGolgi 1/// apparatussulfotransferase biosynthetic /// membrane process activity /// ////// inflammatory [heparanintegral to sulfate]-glucosamine membrane response /// smoothened N-sulfotransferase signaling pathway activity /// /// respiratory transferase gaseous activity exchange/// hydrolase /// fibroblast activity growth factor receptor signaling pathway /// embryonic development /// organ morphogenesis /// heparan sulfate proteoglycan biosynthetic process /// glycosaminoglycan metabolic process /// forebrain development /// midbrain development /// embryonic neurocranium morphogenesis /// embryonic viscerocranium morphogenesis 220488_s_at 0.0027893 220488_s_at BCAS3 breast carcinoma--- amplified sequence--- 3 --- nucleus /// cytoplasm 214678_x_at 0.00281902 214678_x_at ZFX zinc finger protein,--- X-linkedtranscription ///nucleic regulation acid binding ofintracellular transcription /// DNA /// binding nucleus /// /// DNA nucleus binding /// nucleolus/// transcription /// intracellular coactivator membrane-bounded activity /// zinc ion organelle binding /// transcription regulator activity /// metal ion binding 212057_at 0.00283424 212057_at KIAA0182 KIAA0182 ------protein bindingintracellular /// protein binding /// zinc ion binding /// metal ion binding 210054_at 0.0028809 210054_at HAUS3 HAUS augmin-like--- complex,cell subunit cycle 3 /// mitosis--- /// spindlecentrosome assembly /// /// spindle centrosome /// microtubule organization /// HAUS/// cell complex division 209435_s_at 0.0028877 209435_s_at ARHGEF2 Rho/Rac guanine--- nucleotidecell exchange morphogenesis factorguanyl-nucleotide (GEF) /// intracellular2 intracellular exchange protein /// factor transportcytoplasm activity /// /// actin/// Golgi Rho filament apparatus guanyl-nucleotide organization /// spindle exchange /// /// negative microtubule factor regulation activity /// microtubule of/// microtubule Rho guanyl-nucleotide /// tight depolymerization junction exchange/// cell /// junction cell factor cycle activity/// /// cell mitosis soma/// protein ////// dendriticintracellular binding shaft /// signaling microtubule cascade binding /// ///regulation zinc ion of binding Rho protein /// zinc signal ion binding transduction /// Rho /// GTPase regulation binding of Rho /// proteindiacylglycerol signal transductionbinding /// Rac /// guanyl-nucleotideregulation of cell proliferation exchange factor /// cell activity division /// metal ion binding /// Rac GTPase binding 205926_at 0.00294989 205926_at IL27RA interleukin 27 ---receptor, alphapositive regulationreceptor of T-helper activityintegral ///1 type transmembrane to immune plasma membraneresponse receptor /// /// negativeactivity membrane /// regulation protein /// integral binding of T-helper to ///membrane interleukin-27 2 type immune receptor response activity /// immune response /// cell surface receptor linked signal transduction /// positive regulation of interferon-gamma production /// regulation of isotype switching to IgG isotypes /// defense response to Gram-positive bacterium 222031_at 0.0029549 222031_at LOC286434 ///hypothetical LOC389906 protein ---/// LOC729162 LOC286434--- /// similar--- to Serine/threonine-protein--- kinase PRKX (Protein kinase PKX1) /// similar to hCG1981372 209833_at 0.00298393 209833_at CRADD CASP2 and RIPK1Apoptosis_KEGG adaptor ///protease apoptosis with deathbinding /// intracellularinduction domain /// cysteine-type of apoptosis endopeptidase /// signal transduction activity /// /// protein induction binding of apoptosis /// protein via binding death domain/// protein receptors binding /// /// regulation protein binding, of apoptosis bridging /// death domain binding 216264_s_at 0.00298479 216264_s_at LAMB2 laminin, beta 2Inflammatory_Response_Pathway ///structural axon extension moleculeextracellular involved activity region ///in regeneration protein /// proteinaceous binding /// basement membrane /// basal lamina /// endoplasmic reticulum /// laminin-11 complex 214237_x_at 0.00298573 214237_x_at PAWR PRKC, apoptosis,--- WT1, regulatornegative regulationtranscription of transcription corepressornucleus from/// activitynucleus RNA polymerase ////// proteinnucleus IIbinding /// promoter nucleus /// protein ////// transcriptioncytoplasm binding ////// /// cytoplasmenzyme apoptosis binding /// /// cytoplasm apoptosis /// leucine ////// zipper cytoplasmnegative domain regulation /// plasmabinding of membrane cell proliferation /// negative regulation of B cell proliferation /// interleukin-2 biosynthetic process /// negative regulation of T cell proliferation /// positive regulation of amyloid precursor protein biosynthetic process /// positive regulation of apoptosis /// regulation of transcription /// negative regulation of T cell receptor signaling pathway 215470_at 0.00303554 215470_at GTF2H2B general transcription--- factor ---IIH, polypeptide--- 2B --- 206103_at 0.00305992 206103_at RAC3 ras-related C3Integrin-mediated_cell_adhesion_KEGG signaling 3nucleotide (rho family, cascade binding intracellularsmall /// /// GTPsmall GTPase binding GTPase/// cytoplasmactivity protein mediated /// Rac3)/// protein endomembranesignal binding transduction /// systemprotein /// cell ///binding projectionendomembrane /// GTP assembly binding system /// actin/// membrane cytoskeleton /// lamellipodiumorganization /// /// neuron growth projection cone /// filamentousdevelopment /// Integrin-mediated_cell_adhesion_KEGG process /// neuron controlling projection balance /// ///cell neuromuscular soma process 209407_s_at 0.003087 209407_s_at DEAF1 deformed epidermal--- autoregulatorytranscription factor ///DNA 1 transcription(Drosophila) binding ///extracellular fromdouble-stranded RNA polymeraseregion DNA/// nucleus IIbinding promoter /// /// nucleus RNA/// transcription polymerase /// transcription IIfrom transcription RNA factor polymerase complex factor activityII promoter /// binding /// germ /// cell zinc development ion binding ////// transcriptionanatomical structure activator morphogenesis activity /// metal /// ionregulation binding of transcription 205968_at 0.00310499 205968_at KCNS3 potassium voltage-gated--- channel,transport delayed-rectifier, /// ionion transportchannel subfamily activity ///cytoplasm potassium /// S, voltage-gatedmember /// ion Golgi transport 3 apparatus ion /// channel potassium/// plasma activity ion membrane ///transport voltage-gated /// /// plasma transmembrane potassium membrane channel transport /// voltage-gated activity /// delayed potassium rectifier channel potassium complex channel /// membrane activity /// potassiumintegral to channelmembrane activity /// protein binding /// potassium channel regulator activity /// potassium ion binding 201829_at 0.00311746 201829_at NET1 neuroepithelial--- cell transformingregulation 1 of cellguanyl-nucleotide growth /// intracellularsignal exchange transduction /// factor nucleus /// activity intracellular/// cytoplasm /// guanyl-nucleotide signaling cascade exchange /// regulation factor activity of Rho ///protein Rho signalguanyl-nucleotide transduction exchange factor activity 213942_at 0.00315485 213942_at MEGF6 multiple EGF-like-domains--- 6--- calcium ion bindingextracellular /// calcium region ion binding 202206_at 0.00317669 202206_at ARL4C ADP-ribosylation--- factor-like small4C GTPase nucleotidemediated signal bindingintracellular transduction /// GTPase /// nucleusactivity ////// nucleusGTP binding 202710_at 0.00318349 202710_at BET1 blocked early ---in transport 1 transporthomolog (S./// ERcerevisiae)protein to Golgi binding vesicle-mediatedGolgi membrane transport /// endoplasmic /// protein reticulum transport /// /// Golgi vesicle-mediated apparatus /// transportmembrane /// integral to membrane 221656_s_at 0.00321634 221656_s_at ARHGEF10L Rho guanine nucleotide--- exchangeregulation factor of (GEF)Rhoguanyl-nucleotide protein 10-like signalintracellular transductionexchange /// factor cytoplasm /// positiveactivity /// ///regulation cytosol Rho guanyl-nucleotide of transcription exchangevia sterol regulatoryfactor activity element /// Rho binding GTPase /// activator positive regulationactivity of stress fiber formation 211228_s_at 0.00322764 211228_s_at RAD17 RAD17 homolog--- (S. pombe)DNA replicationnucleotide checkpoint binding ///nucleus DNA /// damage///protein nucleus bindingcheckpoint /// nucleus /// ATP/// ///DNAbinding nucleolus repair /// ///nucleoside-triphosphatase /// DNA cytoplasm repair /// response activity to DNA damage stimulus /// response to DNA damage stimulus /// cell cycle /// mitotic cell cycle checkpoint /// negative regulation of DNA replication /// regulation of phosphorylation 209440_at 0.00325446 209440_at PRPS1 phosphoribosyl--- pyrophosphatepurine synthetase base metabolicnucleotide 1 process bindingsoluble /// /// purine fraction magnesium nucleotide /// cytosol ion biosyntheticbinding /// protein /// ribose process complex phosphate /// AMP biosyntheticdiphosphokinase process activity /// pyrimidine /// ribose phosphatenucleotide diphosphokinasebiosynthetic process activity /// nervous /// ribose system phosphate development diphosphokinase /// nucleoside activity metabolic /// ribose process phosphate /// ribonucleoside diphosphokinase monophosphate activity /// ribose biosynthetic phosphate process diphosphokinase /// ribonucleoside activity monophosphate /// ATP binding biosynthetic /// ATP binding process /// ///sugar nucleotide binding biosynthetic/// AMP binding process /// kinase /// ribose activity phosphate /// transferase metabolic activity process /// /// GDP urate binding biosynthetic /// protein process homodimerization /// cellular biosynthetic activity /// process ADP binding /// hypoxanthine /// metal ion biosynthetic binding process 212291_at 0.00332898 212291_at HIPK1 homeodomain--- interacting proteintranscription kinase 1///nucleotide protein aminobindingnucleus acid /// phosphorylation///DNA nucleus binding /// /// nucleolus ///protein smoothened kinase/// cytoplasm activity signaling ////// pathwaycytoplasmprotein serine/threonine /// /// positive centrosome regulation kinase /// PML ofactivity cellbody proliferation /// nuclearprotein ///bindingspeck anterior/posterior /// protein binding pattern /// formation ATP binding /// DNA/// kinase damage activity response, /// transferase signal transduction activity by p53 class mediator resulting in induction of apoptosis /// regulation of transcription 209996_x_at 0.00334583 209996_x_at PCM1 pericentriolar ---material 1 MAPKKK cascadenucleotide /// ureteric bindingpericentriolar bud /// development protein material kinase /// ///neuralactivity cytoplasm crest /// protein cell /// migration cytoplasm tyrosine /// kinase/// embryonic centrosome activity epithelial /// /// protein centrosome tube tyrosine formation /// kinasecytoskeleton /// proteinactivity /// amino/// membrane transmembrane acid phosphorylation /// integral receptor to membrane/// protein protein tyrosine ///amino nonmotile kinaseacid phosphorylation activityprimary /// receptor /// /// homophilic centriolar activity /// satellitecell calcium adhesion ion ///binding signal /// transduction protein binding /// transmembrane /// protein binding receptor /// ATP protein binding tyrosine /// kinase kinase activity signaling /// transferasepathway /// activity nervous system development /// posterior midgut development /// cilium assembly /// cilium assembly /// neuron maturation /// enteric nervous system development /// centrosome organization 221190_s_at 0.00334774 221190_s_at C18orf8 chromosome 18--- open readingendocytosis frame 8 ///receptor lysosomal activity transportnuclear /// transmembrane envelope/// lysosomal /// nuclear transportreceptor envelope activity/// bile /// acid/// lysosome protein metabolic binding /// processlysosome /// protein/// /// bile endosome bindingacid metabolic /// /// hedgehog endoplasmic process receptor /// reticulum negative activity ///regulation ///endoplasmic sterol of transporter macroautophagy reticulum activity /// integral /// cholesterol to plasma transport membrane /// cholesterol /// integral efflux to plasma /// cholesterol membrane homeostasis /// membrane /// cholesterol/// integral homeostasisto membrane /// /// response integral toto cadmiummembrane ion /// perinuclear region of cytoplasm /// perinuclear region of cytoplasm 202590_s_at 0.00339804 202590_s_at PDK2 pyruvate dehydrogenaseKrebs-TCA_Cycle metabolictwo-component2 processnucleus sensor /// glucose/// activity nucleolus metabolic /// nucleotide /// mitochondrion process binding /// glucose ////// proteinmitochondrion metabolic kinase process activity/// mitochondrial /// /// signal protein transduction matrix histidine /// kinasepyruvate /// peptidyl-histidine activity dehydrogenase /// pyruvate phosphorylation complex dehydrogenase (acetyl-transferring) kinase activity /// pyruvate dehydrogenase (acetyl-transferring) kinase activity /// protein binding /// ATP binding /// kinase activity /// transferase activity /// protein complex binding /// protein homodimerization activity /// protein heterodimerization activity 208374_s_at 0.0034369 208374_s_at CAPZA1 capping protein--- (actin filament)protein muscle complex Z-line,actin assembly bindingalpha 1 /// ///cytoskeleton cell actin motion binding /// /// cytoskeleton ///actin protein cytoskeleton binding /// F-actin organization capping ///protein actin complex filament /// capping F-actin capping protein complex /// actin cytoskeleton 207983_s_at 0.00346516 207983_s_at STAG2 stromal antigen--- 2 cell cycle /// chromosomebinding /// protein segregationchromatin binding ////// nucleusmitosis /// meiosisnucleus ////// cellnucleus division /// cytoskeleton 221455_s_at 0.00348208 221455_s_at WNT3 wingless-type Wnt_signaling family, formationsignal member transducer /// Wnt3 extracellular receptor activity signaling /// region extracellular ///pathway, extracellular matrix calcium structural region modulating /// constituent proteinaceous pathway /// /// proteinextracellular cell-cell binding signaling matrix /// multicellular organismal development /// anatomical structure morphogenesis /// anterior/posterior pattern formation /// Wnt receptor signaling pathway /// anatomical structure formation involved in morphogenesis /// Spemann organizer formation at the anterior end of the primitive streak 200821_at 0.00349265 200821_at LAMP2 lysosomal-associated--- membrane--- protein 2--- membrane fraction /// lysosome /// lysosome /// lysosomal membrane /// endosome /// late endosome /// late endosome /// plasma membrane /// plasma membrane /// membrane /// integral to membrane /// platelet membrane /// platelet dense granule membrane 221788_at 0.0035711 221788_at ------214257_s_at 0.00357767 214257_s_at ------208816_x_at 0.0035868 208816_x_at ANXA2P2 annexin A2 pseudogene--- 2 angiogenesis ///phospholipase body fluid secretionextracellular inhibitor ///activity collagenregion /// /// calciumfibril proteinaceous organization ion binding extracellular /// /// fibrinolysis calcium-dependent matrix /// basement phospholipid membrane binding /// /// cytoplasm phosphatidylinositol-4,5-bisphosphate /// early endosome /// sarcolemma binding /// /// melanosome cytoskeletal /// protein protein binding complex /// ///Rab perinuclear GTPase binding region of cytoplasm 218277_s_at 0.00365506 218277_s_at DHX40 DEAH (Asp-Glu-Ala-His)--- box--- polypeptide 40nucleotide binding--- /// nucleic acid binding /// helicase activity /// ATP binding /// ATP-dependent helicase activity /// hydrolase activity 218738_s_at 0.00367222 218738_s_at RNF138 ring finger protein--- 138 Wnt receptor signalingprotein binding pathwayintracellular /// /// zinc modification-dependent ion binding /// ligase activity protein ///catabolic protein process kinase binding /// metal ion binding 205963_s_at 0.00367466 205963_s_at DNAJA3 DnaJ (Hsp40) ---homolog, subfamilymitochondrial A, member smallDNA 3 replicationGTPase nucleusregulator /// protein /// activity mitochondrion folding /// protein/// apoptosis /// binding mitochondrial /// /// activation-induced protein matrix binding /// mitochondrial /// cell zinc death ion ofbinding matrix T cells ////// /// heatcytosol mitochondrion shock /// proteinactin organization filament binding /// /// ///mitochondrial metal small ion GTPase binding mediated /// unfolded signal protein transduction binding /// cell aging /// cell death /// negative regulation of cell proliferation /// embryonic development /// T cell differentiation in the thymus /// positive regulation of T cell proliferation 213090_s_at 0.00368352 213090_s_at TAF4 TAF4 RNA polymerase--- II, TATAovarian box folliclebindingDNA development protein binding (TBP)-associated ///nucleus /// DNA transcription binding/// nucleus factor, /// /// transcription /// 135kDatranscription transcription factor initiation factor activity TFIID /// ///regulation complex transcription of/// transcription, transcription factor activity DNA-dependentfactor /// transcriptionTFIID complex /// regulationcoactivator /// transcription of activity transcription factor /// protein TFIID from binding complexRNA polymerase /// /// protein nucleolus II binding promoter /// cytoplasm /// ///general transcription /// RNA transcription polymerase initiation factor IIfrom transcription TFTC RNA complex polymerase factor activity II promoter /// transcription /// interspecies activator interaction activity between /// transcription organisms initiation /// regulation factor activityof transcription /// transcription initiation factor activity 37802_r_at 0.00374534 37802_r_at FAM63B family with sequence--- similarity--- 63, member--- B --- 220583_at 0.00377139 220583_at ------209845_at 0.00378699 209845_at MKRN1 makorin ring finger--- protein 1--- nucleic acid binding--- /// chromatin binding /// protein binding /// protein binding /// zinc ion binding /// metal ion binding 211733_x_at 0.00380676 211733_x_at SCP2 sterol carrier proteinMitochondrial_fatty_acid_betaoxidationcatalytic process activity cytoplasm/// /// transport sterol /// carrier ///mitochondrion lipid activity transport /// /// sterol ///peroxisome peroxisome carrier activity/// organizationperoxisome /// protein /// bindingmetabolic /// process protein binding /// lipid binding /// oxidoreductase activity /// transferase activity /// transferase activity, transferring acyl groups other than amino-acyl groups /// propanoyl-CoA C-acyltransferase activity 206698_at 0.0038465 206698_at XK X-linked Kx blood--- group (McLeodtransport syndrome) /// transporttransporter /// activity aminomembrane acid/// protein transport /// integral binding to membrane /// integral to membrane 216906_at 0.00386247 216906_at ST14 suppression of--- tumorigenicityproteolysis 14 (colon /// carcinoma)catalytic proteolysis activityextracellular /// serine-type region endopeptidase /// plasma membrane activity /// /// peptidase integral to activity plasma /// membrane serine-type /// peptidase membrane activity /// integral /// serine-type to membrane peptidase /// extrinsic activity to /// plasma hydrolase membrane activity 212717_at 0.00388505 212717_at PLEKHM1 pleckstrin homology--- domainintracellular containing, signalingfamilyzinc ion M (withcascadebinding cytoplasmRUN /// domain) diacylglycerol member binding 1 /// metal ion binding 202506_at 0.00394006 202506_at SSFA2 sperm specific--- antigen 2 --- actin binding cytoplasm /// plasma membrane 209597_s_at 0.00396935 209597_s_at PNMA2 paraneoplastic--- antigen MA2--- protein bindingnucleus /// nucleolus 212156_at 0.0039713 212156_at VPS39 vacuolar protein--- sorting 39 homologtransport (S./// cerevisiae)proteinsmall GTPase transport cytoplasmregulator activity /// lysosome /// protein /// endosome binding /// membrane /// extrinsic to membrane /// HOPS complex 206518_s_at 0.0039805 206518_s_at RGS9 regulator of G-proteinCalcium_regulation_in_cardiac_cellssignal /// transducer G-proteinnucleus activity coupled /// cytoplasm/// receptor GTPase /// proteinactivator heterotrimeric signaling activity pathwayG-protein/// GTPase /// complex activatordopamine /// activity receptormembrane /// signaling protein /// extrinsic binding pathway to /// membrane /// protein intracellular complex signaling binding cascade /// nervous /// systemSmooth_muscle_contraction visual perception /// regulation of G-protein coupled receptor protein signaling pathway /// regulation of G-protein coupled receptor protein signaling pathway /// negative regulation of signal transduction /// positive regulation of GTPase activity /// response to estrogen stimulus /// response to stimulus 212497_at 0.00400338 212497_at MAPK1IP1L mitogen-activated--- protein kinase--- 1 interacting--- protein 1-like--- 209022_at 0.00401473 209022_at STAG2 stromal antigen--- 2 cell cycle /// chromosomebinding /// protein segregationchromatin binding ////// nucleusmitosis /// meiosisnucleus ////// cellnucleus division /// cytoskeleton 203464_s_at 0.00404261 203464_s_at EPN2 epsin 2 --- endocytosis ///lipid regulation binding ofcytoplasm endocytosis /// clathrin coat of endocytic vesicle /// clathrin-coated vesicle /// cytoplasmic vesicle 214352_s_at 0.00411677 214352_s_at KRAS v-Ki-ras2 KirstenG_Protein_Signaling ///nucleotide apoptosis homolog binding ///intracellular signal /// transductionGTPase /// membraneactivity /// ///small fractionprotein GTPase ///binding mediatedplasma /// membraneprotein signal bindingtransduction /// plasma /// GTP /// membrane bindingRas protein /// /// GMP signalmembrane binding transduction /// GDPmembrane /// ///binding MAPK_Cascade binding /// cell aging /// positive regulation of cell proliferation /// visual learning /// cytokine-mediated signaling pathway /// actin cytoskeleton organization /// regulation of synaptic transmission, GABAergic /// positive regulation of Rac protein signal transduction /// positive regulation of MAP kinase activity /// negative regulation of neuron apoptosis /// positive regulation of DNA replication /// regulation of long-term neuronal synaptic plasticity /// positive regulation of nitric-oxide synthase activity /// positive regulation of NF-kappaB transcription factor activity /// striated muscle cell differentiation /// protein heterooligomerization /// response to glucocorticoid stimulus /// response to mineralocorticoid stimulus 219401_at 0.0041318 219401_at XYLT2 xylosyltransferase--- II glycosaminoglycanacetylglucosaminyltransferase biosyntheticendoplasmic process reticulum activity /// /// Golgi transferase apparatus activity /// membrane /// transferase /// integral activity, to transferringmembrane glycosyl groups /// protein xylosyltransferase activity /// protein xylosyltransferase activity 203921_at 0.00416978 203921_at CHST2 carbohydrate (N-acetylglucosamine-6-O)--- carbohydrate metabolicsulfotransferaseN-acetylglucosamine processGolgi 2 /// membrane 6-O-sulfotransferaseN-acetylglucosamine /// Golgi apparatus activitymetabolic ////// processsulfotransferasetrans-Golgi /// sulfur network activity metabolic /// membrane/// processsulfotransferase ////// integralinflammatory activity to membrane /// response transferase /// /// intrinsic inflammatory activity to Golgi response membrane /// multicellular organismal development 209605_at 0.0041704 209605_at TST thiosulfate sulfurtransferase--- sulfate (rhodanese) transportthiosulfate /// cyanate sulfurtransferasemitochondrion catabolic process activity/// mitochondrion /// thiosulfate /// mitochondrialsulfurtransferase inner activity membrane /// transferase /// mitochondrial activity matrix /// mitochondrial matrix /// plasma membrane 217138_x_at 0.00419743 217138_x_at IGL@ Immunoglobulin--- lambda locustransport /// exocytosis--- /// proteinexocyst transport/// cytoplasm /// microtubule organizing center /// cytosol /// plasma membrane /// membrane /// extrinsic to membrane /// centriolar satellite 205070_at 0.00420103 205070_at ING3 inhibitor of growth--- family, membertranscription 3 ///histone chromatin acetyltransferase modificationnucleus /// Piccolo activity/// regulation NuA4/// protein histone of growth binding acetyltransferase /// /// positive zinc ion regulation bindingcomplex /// of/// apoptosismetal NuA4 ion histone ///binding histone acetyltransferase H4 acetylation complex /// histone H2A acetylation /// regulation of transcription 203783_x_at 0.00423428 203783_x_at POLRMT polymerase (RNA)--- mitochondrialtranscription (DNA directed) ///DNA transcription binding ///mitochondrion fromDNA-directed mitochondrial /// RNA mitochondrion polymerasepromoter ///activity mitochondrial /// DNA-directed nucleoid RNA polymerase activity /// protein binding /// transferase activity /// nucleotidyltransferase activity 218688_at 0.00423599 218688_at DAK dihydroxyacetone--- kinase 2 homologglycerol metabolic(S. cerevisiae)nucleotide process binding--- /// magnesium ion binding /// catalytic activity /// glycerone kinase activity /// ATP binding /// kinase activity /// transferase activity /// lyase activity /// manganese ion binding /// FAD-AMP lyase (cyclizing) activity /// metal ion binding /// cobalt ion binding 202855_s_at 0.00424445 202855_s_at SLC16A3 solute carrier family--- 16, membertransport 3 (monocarboxylic /// organicmonocarboxylic anion acid transportmembrane transporteracid transmembrane /// fraction monocarboxylic 4) /// plasmatransporter acid membrane transport activity /// ////// integral symportertransmembrane to plasma activity transport membrane /// secondary /// membraneactive monocarboxylate /// integral to transmembrane membrane transporter activity 203353_s_at 0.00429229 203353_s_at MBD1 methyl-CpG binding--- domaintranscription protein 1 ///DNA transcription binding ///chromatin fromDNA RNAbinding /// polymerase heterochromatin /// transcription II promoter /// factor nucleus /// activity negative /// nucleus/// regulation transcription /// cytoplasm of transcription corepressor /// nuclear activity/// regulation speck /// protein of transcription binding /// zinc ion binding /// methyl-CpG binding /// transcription repressor activity /// metal ion binding 222113_s_at 0.0043561 222113_s_at EPS15L1 epidermal growth--- factor receptorendocytosis pathway ///receptor substrate oxidation activity 15-likereductionnucleus /// 1 calcium /// plasma ion binding membrane /// protein /// plasma binding membrane /// oxidoreductase /// coated pitactivity /// membrane /// transition /// extrinsicmetal ion to binding membrane 212064_x_at 0.00435661 212064_x_at MAZ MYC-associated--- zinc finger proteintranscription (purine-binding ///nucleic transcription acid transcription bindingintracellular initiation /// factor) DNA from /// binding nucleus RNA polymerase /// RNA binding II promoter /// protein /// termination binding /// ofprotein RNA polymerasebinding /// zincII transcription ion binding ////// regulationmetal ion bindingof transcription 209015_s_at 0.00437532 209015_s_at DNAJB6 DnaJ (Hsp40) ---homolog, subfamilyprotein B, folding memberATPase /// 6response activator nucleusto unfoldedactivity /// ///nucleus protein DNA binding////// cytoplasmnegative /// protein regulation /// perinuclear binding of caspase /// region protein activity of bindingcytoplasm /// intermediate/// transcription/// perinuclear filament repressor region organization of activity cytoplasm ////// heatnegative shock regulation protein binding of transcription, /// heat shock DNA-dependent protein binding /// chaperone binding 207193_at 0.00439676 207193_at AGRP agouti related ---protein homologneuropeptide (mouse) signalingreceptor bindingpathwayextracellular /// /// neuropeptide neuropeptide region hormone signaling activity pathway /// ///neuropeptide feeding behavior hormone /// activityadult feeding behavior /// hormone-mediated signaling /// eating behavior 213628_at 0.0044049 213628_at CLCC1 chloride channel--- CLIC-like 1chloride transportchloride channelnucleus activity /// cytoplasm /// endoplasmic reticulum /// endoplasmic reticulum /// microsome /// Golgi apparatus /// membrane /// integral to membrane /// intracellular membrane-bounded organelle 217608_at 0.00444133 217608_at SFRS12IP1 SFRS12-interacting--- protein mRNA1 processingnucleic /// acidRNA bindingsplicing--- /// zinc ion binding /// metal ion binding 208163_s_at 0.00444137 208163_s_at OSBPL7 oxysterol binding--- protein-liketransport 7 /// lipid--- transport ---/// steroid metabolic process 210421_s_at 0.00444885 210421_s_at SLC24A1 solute carrier family--- 24 (sodium/potassium/calciumtransport /// transportcalcium ion /// exchanger), bindingionmembrane transport /// memberprotein fraction /// calcium binding 1 /// integral ion /// transport calcium, to plasma ///potassium:sodium calcium membrane ion transport/// membraneantiporter /// visual activity /// integral perception /// calcium, to membrane /// visualpotassium:sodium perception/// outer membrane /// antiporter response activityto light ///intensity symporter /// response activity ///to stimulusantiporter /// activity transmembrane transport 213308_at 0.00446894 213308_at SHANK2 SH3 and multiple--- ankyrin repeatintracellular domains signaling protein2 bindingcascadecytoplasm /// protein /// binding plasma /// membrane protein binding /// postsynaptic /// SH3 domain density binding /// membrane /// GKAP/Homer /// cell junction scaffold /// activity synapse /// postsynaptic membrane 52169_at 0.0045045 52169_at STRADA STE20-related--- kinase adaptorprotein alpha amino nucleotideacid phosphorylation bindingnucleus /// ///protein proteinnucleus kinase amino/// activitycytoplasm acid phosphorylation/// ///protein cytoplasm kinase /// activity protein /// export protein from binding nucleus /// /// ATP cell binding cycle /// activationkinase activity of protein /// transferase kinase activity activity 210546_x_at 0.00450493 210546_x_at CTAG1A /// CTAG1Bcancer/testis antigen--- 1A /// ---cancer/testis proteinantigen binding1B cytoplasm /// cytoplasm 219246_s_at 0.00450499 219246_s_at OGFOD2 2-oxoglutarate--- and iron-dependentoxidation oxygenase reductioniron ion domain binding containing--- /// protein 2 binding /// oxidoreductase activity /// oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen /// oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen /// L-ascorbic acid binding /// metal ion binding 215093_at 0.00450516 215093_at NSDHL NAD(P) dependentCholesterol_Biosynthesis developmentC-3 sterol dehydrogenase ///endoplasmic steroid biosynthetic (C-4reticulum sterol process ///decarboxylase) endoplasmic /// cholesterol activityreticulum biosynthetic /// membrane catalytic process activity /// membrane/// ///cholesterol 3-beta-hydroxy-delta5-steroid /// integralbiosynthetic to membrane process /// dehydrogenase metabolic process activity /// ///cholesterol 3-beta-hydroxy-delta5-steroid metabolic process /// lipid dehydrogenase biosynthetic activity process /// /// binding sterol biosynthetic /// oxidoreductase process activity /// oxidation /// sterol-4-alpha-carboxylate reduction 3-dehydrogenase (decarboxylating) activity 207688_s_at 0.0045168 207688_s_at ------transforming growthextracellular factor regionbeta receptor /// extracellular binding /// region hormone activity /// growth factor activity 217321_x_at 0.00452753 217321_x_at ATXN3 Ataxin 3 --- nucleotide-excisionubiquitin repair thiolesterase ///nucleus transcription /// activity nucleoplasm /// /// synaptic protein /// transmissionbindingcytoplasm /// ///hydrolase /// nuclear nervous activitymatrix system development /// cell death /// regulation of transcription 218763_at 0.00455935 218763_at STX18 syntaxin 18 --- transport /// intracellularSNAP receptor proteinendoplasmic activity transport /// proteinreticulum /// ER binding to /// Golgi endoplasmic vesicle-mediated reticulum transport /// Golgi /// apparatus protein transport/// membrane /// vesicle-mediated /// integral to membrane transport 222239_s_at 0.00456062 222239_s_at INTS6 integrator complex--- subunit 6snRNA processingtransmembranenucleus receptor /// activitynucleus ////// proteinnucleolus binding /// cytoskeleton /// integrator complex 214865_at 0.00458243 214865_at DOT1L DOT1-like, histone--- H3 methyltransferasechromatin modification (S.DNA cerevisiae) binding ///nucleus methyltransferase activity /// transferase activity /// histone-lysine N-methyltransferase activity 213545_x_at 0.00458918 213545_x_at SNX3 sorting 3--- transport /// endocytosisprotein binding ///cytoplasm cell /// communicationprotein binding /// protein transportphosphatase binding /// phosphoinositide binding 200971_s_at 0.00459251 200971_s_at SERP1 stress-associated--- endoplasmicskeletal reticulum system protein--- development 1 endoplasmic /// glucose reticulummetabolic ///process endoplasmic /// protein reticulum modification /// ribosome process /// /// membrane protein amino /// integral acid glycosylation to membrane /// transport /// response to stress /// plasma membrane organization /// post-embryonic development /// multicellular organismal aging /// protein transport /// endoplasmic reticulum unfolded protein response /// positive regulation of insulin secretion /// positive regulation of translation /// positive regulation of organ growth /// muscle organ morphogenesis /// transmembrane transport /// positive regulation of growth hormone secretion /// intracellular protein transmembrane transport 221194_s_at 0.00460666 221194_s_at RNFT1 ring finger protein,--- transmembrane--- 1 protein bindingmembrane /// zinc ion /// binding integral /// to metal membrane ion binding 219516_at 0.00462892 219516_at TRPV4 transient receptor--- potential transportcation channel, /// ionreceptor subfamily transport activity V,///plasma member calcium/// osmosensor membrane 4ion transport activity/// plasma /// /// calcium ionmembrane channel ion transport ///activity cilium /// /// /// calcium cation membrane channelion transport /// activity integral /// /// cellularto calcium membrane calcium channel /// ion integral activity homeostasis to/// membrane calcium /// cell channel volume activity homeostasis /// calcium /// response ion binding to osmotic /// protein stress binding /// hypotonic /// protein response binding /// /// elevation calmodulin of cytosolicbinding ///calcium calmodulin ion concentration binding /// identical/// osmosensory protein binding signaling pathway /// osmosensory signaling pathway /// response to mechanical stimulus /// vasopressin secretion /// hyperosmotic salinity response /// regulation of response to osmotic stress /// transmembrane transport 53912_at 0.00476382 53912_at SNX11 sorting nexin 11--- transport /// cellprotein communication binding--- /// phosphoinositide/// protein transport binding 203857_s_at 0.00484265 203857_s_at PDIA5 protein disulfide--- isomerase familyprotein A, folding memberprotein /// 5response disulfide endoplasmicto isomerasestress /// responsereticulumactivity /// to/// proteinstress endoplasmic /// disulfide cell redoxreticulum isomerase homeostasis lumen activity /// /// endoplasmic/// oxidation oxidoreductase reduction reticulum activity lumen /// isomerase activity 206127_at 0.00485053 206127_at ELK3 ELK3, ETS-domain--- protein (SRFangiogenesis accessory ///DNA protein transcription binding 2) ///nucleus ///transcription regulation /// nucleus factor of transcription, /// activity nucleus /// /// DNA-dependenttranscription nucleolus /// factor mitochondrion /// signalactivity transduction /// /// transcription intracellular /// negative corepressor membrane-bounded regulation activity of ///transcription organelle protein binding /// wound /// purine-rich healing /// negative regulation regulatory of transcription element binding /// sequence-specific DNA binding 220762_s_at 0.00487304 220762_s_at GNB1L guanine nucleotide--- binding proteinG-protein (G coupledprotein),--- receptor beta polypeptide proteininternal signaling side 1-like of plasma pathway membrane /// intracellular signaling cascade /// social behavior 219861_at 0.0048797 219861_at DNAJC17 DnaJ (Hsp40) ---homolog, subfamilyprotein C, folding memberRNA 17binding ///--- heat shock protein binding /// unfolded protein binding 217653_x_at 0.00490443 217653_x_at ------201850_at 0.00493902 201850_at CAPG capping protein--- (actin filament),protein gelsolin-like complexactin assembly binding ///nucleus cell projection /// cytoplasm assembly /// F-actin /// barbed-end capping proteinactin filament complex capping /// melanosome /// actin filament capping 210405_x_at 0.00494743 210405_x_at TNFRSF10B tumor necrosisApoptosis /// apoptosisreceptor member activity /// 10b activationplasma /// receptor membrane of caspase activity /// activity membrane/// protein /// signal ///binding integral transduction /// toprotein membrane /// binding cell surface/// /// integral protein receptor to binding membrane linked /// signal caspase transduction activator activity/// activation /// TRAIL of NF-kappaB-inducing binding kinase activity /// induction of apoptosis via death domain receptors /// activation of pro-apoptotic gene products /// regulation of apoptosis /// positive regulation of I-kappaB kinase/NF-kappaB cascade 203017_s_at 0.00495832 203017_s_at SSX2IP synovial sarcoma,--- X breakpointcell adhesion2 interactingprotein protein bindingnucleus /// protein /// adherens binding ///junction actinin /// binding cell-cell adherens junction /// cell junction /// protein complex 211661_x_at 0.00503415 211661_x_at PTAFR platelet-activatingGPCRDB_Class_A_Rhodopsin-like productionlipopolysaccharide /// chemotaxisplasma binding membrane/// chemotaxis /// lipopolysaccharide /// integral/// inflammatory to plasma receptor response membrane activity /// ////// inflammatory signalmembrane transducer ///response membrane activity /// immune /// /// receptor integral response activityto membrane /// /// signal G-protein /// transduction integral coupled to ///membrane receptor G-protein /// Small_ligand_GPCRs coupled signaling receptor pathway activity /// plateletG-protein activating coupled receptorfactor receptor protein activity signaling /// pathwayplatelet activating/// G-protein factor coupled receptor receptor activity protein /// platelet signaling activating pathway factor /// response receptor toactivity lipopolysaccharide /// phospholipid /// bindinginositol trisphosphate biosynthetic process /// phosphoinositide-mediated signaling 220646_s_at 0.00506836 220646_s_at KLRF1 killer cell lectin-like--- receptorcell subfamily surface F,receptor receptormember linked activity1 signalintegral /// transductiontransmembrane to plasma membrane receptor /// activity membrane /// binding /// membrane /// sugar /// binding integral /// to MHC membrane class I receptor activity 212026_s_at 0.00509003 212026_s_at EXOC7 exocyst complex--- componenttransport 7 /// exocytosis--- /// proteinexocyst transport/// cytoplasm /// microtubule organizing center /// cytosol /// plasma membrane /// membrane /// extrinsic to membrane /// centriolar satellite 218712_at 0.00512787 218712_at C1orf109 chromosome 1--- open reading--- frame 109 ------203196_at 0.00512873 203196_at ABCC4 ATP-binding cassette,--- sub-familytransport C (CFTR/MRP), /// ionnucleotide transport member binding ///membrane transmembrane4 /// chloride fraction channel transport /// plasma activity membrane /// ATP binding /// membrane /// 15-hydroxyprostaglandin /// integral to membrane dehydrogenase /// platelet (NAD+)dense granule activity membrane /// ATPase activity /// nucleoside-triphosphatase activity /// ATPase activity, coupled to transmembrane movement of substances 204268_at 0.00523735 204268_at S100A2 S100 calcium ---binding proteinendothelial A2 cellcalcium migration ion binding--- /// calcium ion binding 202566_s_at 0.00524977 202566_s_at SVIL supervillin --- cytoskeleton organizationactin binding /// ///podosome skeletal calcium muscle ///ion nucleus binding tissue ////// development cytoplasmactin filament /// cytoplasm binding /// cytoskeleton /// plasma membrane /// plasma membrane /// actin cytoskeleton /// membrane /// cell projection /// costamere 209628_at 0.00526184 209628_at NXT2 nuclear transport--- factor 2-liketransport export ///factor proteinprotein 2 transportbindingintracellular /// mRNA /// transport nucleus /// cytoplasm 215307_at 0.00527662 215307_at ZNF529 zinc finger protein--- 529 transcription ///nucleic regulation acid binding ofintracellular transcription, /// DNA /// binding nucleusDNA-dependent /// zinc ion /// binding regulation /// metalof transcription ion binding 212145_at 0.00532128 212145_at MRPS27 mitochondrial ---ribosomal protein--- S27 --- mitochondrion /// ribosome /// ribonucleoprotein complex 213630_at 0.00534208 213630_at NACAD NAC alpha domain--- containingtransport /// protein--- transportnucleus /// cytoplasm 219468_s_at 0.0053612 219468_s_at CUEDC1 CUE domain containing--- 1 ------211087_x_at 0.00542866 211087_x_at MAPK14 mitogen-activatedMAPK_Cascade checkpointnucleotide binding/// spindlecell morphogenesis/// pole protein /// cellkinase ////// activitysolubleangiogenesis fraction/// protein /// /// chondrocyte serine/threoninenucleus /// differentiation nucleus kinase /// nucleoplasmactivity /// glucose /// protein /// metabolic cytoplasm serine/threonine process /// cytoplasm /// protein kinase /// aminoactivity cytosol acid /// /// phosphorylationMAP cytosolic kinase part activity /// ///cell MAP motion kinase /// chemotaxiskinase activity /// ///response protein to binding stress ////// responseprotein binding to stress /// ///ATP signal binding transduction /// protein /// C-terminus cell surface binding receptor /// linkedMP kinase signal activity transduction /// kinase /// activityprotein ///kinase transferase cascade activity/// protein kinase cascade /// Ras protein signal transduction /// skeletal muscle tissue development /// fatty acid oxidation /// lipopolysaccharide-mediated signaling pathway /// response to muramyl dipeptide /// response to lipopolysaccharide /// positive regulation of erythrocyte differentiation /// positive regulation of transcription from RNA polymerase II promoter /// protein amino acid autophosphorylation /// stress-activated MAPK cascade 218972_at 0.00552662 218972_at TTC17 tetratricopeptide--- repeat domain--- 17 binding --- 202854_at 0.00553404 202854_at HPRT1 hypoxanthine Nucleotide_Metabolism to amphetamine 1magnesium ion///soluble bindingpurine fraction nucleotide /// magnesium /// cytoplasm biosynthetic ion binding/// processcytoplasm /// purine/// ///purine cytosolbinding ribonucleoside /// hypoxanthine salvage phosphoribosyltransferase /// purine ribonucleoside salvageactivity /// adeninehypoxanthine salvage phosphoribosyltransferase /// guanine salvage /// behavioractivity /// /// hypoxanthine behavior /// grooming phosphoribosyltransferase behavior /// nucleoside activity metabolic /// protein process binding /// /// cytolysis transferase /// striatum activity development/// transferase /// activity, cerebral transferring cortex neuron glycosyl differentiation groups /// /// identical central proteinnervous binding system /// neuron protein development homodimerization /// dopamine activity metabolic /// metal process ion binding /// positive regulation of dopamine metabolic process /// positive regulation of dopamine metabolic process /// adenine metabolic process /// hypoxanthine metabolic process /// hypoxanthine metabolic process /// lymphocyte proliferation /// dendrite morphogenesis /// protein homotetramerization 210099_at 0.00557043 210099_at ABCA2 ATP-binding cassette,--- sub-familyregulation A (ABC1), of transcriptionnucleotide member binding2 fromlysosomal RNA /// nucleotidepolymerase membrane binding II /// promoter microtubule /// ATP /// binding lipid organizing metabolic /// ATP center binding process /// microtubule/// /// ATP transport binding organizing /// /// transport ATPase center activity/// ///cholesterol membrane /// ATPase metabolic /// activity integral process /// tonucleoside-triphosphatase membrane /// regulation /// integralof intracellular to activity membrane cholesterol /// ATPase /// integral transport activity, to membrane/// coupled response to /// transmembrane to cytoplasmic drug /// cholesterol membrane-bounded movement homeostasis of substances vesicle /// response /// cytoplasmic to steroid membrane-bounded hormone stimulus vesicle /// ATP-binding cassette (ABC) transporter complex 214366_s_at 0.0055813 214366_s_at ALOX5 arachidonate 5-lipoxygenaseEicosanoid_Synthesis metabolicarachidonate process 5-lipoxygenasesoluble /// leukotriene fraction activity/// metabolic nucleus /// arachidonate ///process nuclear /// envelope inflammatory5-lipoxygenase /// nuclear response activity envelope /// /// response iron lumen ion bindingto/// nutrient cytoplasm /// calcium/// ///leukotriene cytosol ion binding /// biosynthetic membrane /// protein process /// binding nuclear /// ///lipoxygenase matrix lipoxygenase /// nuclear pathway activity matrix /// /// positive/// oxidoreductase extrinsic regulation to membrane activity of vasoconstriction /// /// oxidoreductase dendrite /// /// oxidation nuclear activity, membrane reduction acting on /// single sarcolemma donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen /// metal ion binding 214840_at 0.00558879 214840_at TOM1L2 target of myb1-like--- 2 (chicken)transport /// intracellular--- proteinintracellular transport /// protein transport 201626_at 0.00559018 201626_at INSIG1 insulin induced--- gene 1 lipid metabolicprotein process binding /// responseendoplasmic /// protein to sterol bindingreticulum depletion /// endoplasmic /// metabolic reticulum process ////// steroidmembrane metabolic /// integral process to ///membrane cholesterol metabolic process /// cell proliferation /// ER-nuclear sterol response pathway 202599_s_at 0.00559145 202599_s_at NRIP1 nuclear receptorOvarian_Infertility_Genes1 regulationtranscription of transcription coactivatorhistone deacetylasefrom activity RNA polymerase/// complex transcription /// II nucleuspromoter coactivator /// /// nucleus negative activity ///regulation transcription of transcription corepressor from activity RNA ///polymerase transcription II promoter corepressor /// ovarian activity follicle /// receptor rupture binding /// transcription /// protein ///binding lipid storage/// protein /// androgenbinding /// receptor estrogen signaling receptor pathway binding /// ovulationnuclear hormone /// regulation receptor of transcriptionbinding /// glucocorticoid /// positive regulation receptor binding of transcription, /// histone DNA-dependent deacetylase binding /// positive /// retinoid regulation X receptor of transcription binding /// from androgen RNA polymerase receptor binding II promoter 209023_s_at 0.00559707 209023_s_at STAG2 stromal antigen--- 2 cell cycle /// chromosomebinding /// protein segregationchromatin binding ////// nucleusmitosis /// meiosisnucleus ////// cellnucleus division /// cytoskeleton 202426_s_at 0.00560339 202426_s_at RXRA retinoid X receptor,Nuclear_ReceptorsDNA ///binding placenta ///nucleus DNAdevelopment binding/// nucleus /// /// DNA ///transcription axon binding /// /// double-stranded regulation of transcription, DNA binding DNA-dependent /// transcription /// factor vitamin activity metabolic /// transcription process /// factor inflammatory activity ///response ligand-regulated /// midgut transcriptiondevelopment factor /// heart activity development /// steroid /// hormone female pregnancyreceptor activity /// aging /// retinoic/// response acid receptorto nutrient activity /// cholesterol /// transcription metabolic coactivator process ///activity negative /// receptor regulation activity of cell /// proliferation ligand-dependent /// response nuclear to receptorselenium activity ion /// ///negative retinoid-X regulation receptor of activityspecific ///transcription steroid binding from RNA/// protein polymerase binding II promoter/// protein /// binding response /// zincto organic ion binding cyclic ///substance transcription /// axon regulator regeneration activity /// /// response vitamin Dto receptor retinoic bindingacid /// ///response sequence-specific to retinoic acid DNA /// binding cellular /// response metal ion to bindinginsulin stimulus/// vitamin /// D response response to element vitamin bindingD /// positive regulation of apoptosis /// interspecies interaction between organisms /// regulation of transcription /// positive regulation of transcription /// positive regulation of transcription from RNA polymerase II promoter /// positive regulation of transcription from RNA polymerase II promoter /// retinoic acid receptor signaling pathway /// response to glucocorticoi 217920_at 0.0056171 217920_at MAN1A2 mannosidase, ---alpha, class 1A,N-glycan member processing 2 mannosyl-oligosaccharide /// respiratoryGolgi membrane gaseous 1,2-alpha-mannosidase exchange/// membrane /// metabolic fraction activity ///process Golgi /// mannosyl-oligosaccharide ///apparatus glycoprotein /// membrane metabolic 1,2-alpha-mannosidase ///process integral /// tolung membrane alveolus activity ///development integral /// calcium to membrane ion binding /// hydrolase activity /// hydrolase activity, acting on glycosyl bonds 207788_s_at 0.00562728 207788_s_at SORBS3 sorbin and SH3--- domain containingnegative 3 regulationstructural of transcription constituentnucleus fromof/// cytoskeleton cytoplasm RNA polymerase /// /// cytoskeleton protein II promoter binding /// focal////// cellprotein adhesion adhesion binding /// /// focal /// cell transcriptionadhesion adhesion /// /// factorcell cell-substrate junction binding /// adhesion vinculin /// binding positive regulation of MAPKKK cascade /// positive regulation of cytoskeleton organization /// positive regulation of stress fiber formation 203446_s_at 0.0056351 203446_s_at OCRL oculocerebrorenal--- syndromelipid of Lowe metabolicinositol process or /// phosphatidylinositol signalintracellular transduction /// Golgi phosphatase stack /// activityGolgi-associated /// inositol vesicle or phosphatidylinositol phosphatase activity /// phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity /// phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity /// hydrolase activity 218053_at 0.00566376 218053_at PRPF40A PRP40 pre-mRNAmRNA_processing_Reactome homologprotein /// A RNAbinding (S. cerevisiae)splicingnucleus /// protein /// nuclear binding speck 210618_at 0.00566623 210618_at RAP1GAP RAP1 GTPase activating--- proteinsignal transductionGTPase /// activity signalintracellular transduction/// GTPase /// activator /// membrane signal activity transduction fraction /// GTPase /// /// Golgi regulation activator apparatus activityof small/// cytosol GTPase /// mediated membrane signal /// extrinsictransduction to membrane 201019_s_at 0.00568176 201019_s_at EIF1AP1 /// EIF1AXeukaryotic translationTranslation_Factors 1A /// pseudogeneRNA translational binding 1/// cytoplasminitiation/// translation eukaryotic /// /// translational initiationcytosol translation factor initiationinitiation activity factor /// translation 1A, X-linked factor activity, nucleic acid binding 217366_at 0.00570307 217366_at CTNNA1 catenin (cadherin-associated--- cell protein), adhesion alpha ///structural cell1, 102kDa adhesion moleculecytoplasm /// activityapical /// junction ///cytoskeleton protein assembly binding /// plasma /// protein membrane binding /// /// adherens vinculin junction binding /// actincadherin cytoskeleton binding /// /// cadherin membrane binding /// cell junction 220281_at 0.00576101 220281_at SLC12A1 solute carrier family--- 12 (sodium/potassium/chloridetransport /// transporttransporter /// transporters), activity ionmembrane transport /// protein fractionmember /// potassium binding /// 1 plasma /// ion sodium:potassium:chloride transportmembrane /// /// sodium plasma ion membrane transport symporter /// activity membranechloride /// transport sodium:potassium:chloride /// integral /// transmembrane to membrane /// symportertransport apical plasma activity membrane /// symporter /// intrinsic activity to/// membrane cation:chloride symporter activity /// potassium ion binding /// sodium ion binding 216974_at 0.00576129 216974_at ------213112_s_at 0.00576697 213112_s_at SQSTM1 sequestosome--- 1 ubiquitin-dependentprotein protein kinasenucleus catabolicC binding /// process ///cytoplasm protein /// apoptosisbinding/// endosome /// /// protein response /// late binding endosometo stress /// zinc /// /// ionimmune cytosol binding ///response ///cytosol protein /// intracellular kinase binding signaling /// receptor cascade tyrosine /// protein kinase localization binding /// /// SH2 endosome domain transportbinding /// /// SH2 cell domaindifferentiation binding /// /// regulation ubiquitin bindingof I-kappaB /// ubiquitin kinase/NF-kappaB binding /// cascade metal ion /// binding regulation of I-kappaB kinase/NF-kappaB cascade /// positive regulation of transcription from RNA polymerase II promoter 221704_s_at 0.00578358 221704_s_at VPS37B vacuolar protein--- sorting 37 homologtransport B/// (S. protein--- cerevisiae) transportendosome /// membrane /// extrinsic to membrane 203988_s_at 0.00579412 203988_s_at FUT8 fucosyltransferase--- 8 (alpha in(1,6) utero fucosyltransferase) embryonicglycoprotein development 6-alpha-L-fucosyltransferaseGolgi ///apparatus protein ///amino Golgi acid apparatus N-linkedactivity /// glycosylation membraneglycoprotein ////// 6-alpha-L-fucosyltransferase N-glycanintegral to processing membrane /// /// transforming Golgi activity /// growth transferase membrane factor activitybeta receptor /// transferase signaling activity, pathway transferring /// integrin-mediated glycosyl groups signaling /// SH3 pathway domain /// binding respiratory /// alpha(1,6)-fucosyltransferase gaseous exchange /// oligosaccharide activity biosynthetic process /// cell migration /// protein amino acid glycosylation in Golgi /// L-fucose catabolic process /// receptor metabolic process 216427_at 0.0058094 216427_at ------205336_at 0.00584045 205336_at PVALB parvalbumin ------calcium ion bindingcytoplasm /// axon 210244_at 0.00590435 210244_at CAMP cathelicidin antimicrobial--- peptidedefense response--- /// defenseextracellular response to region bacterium /// specific /// defense granule response to bacterium /// defense response to Gram-negative bacterium 201928_at 0.00593008 201928_at PKP4 plakophilin 4 --- cell adhesion ///binding cell adhesion /// proteincell-cell binding junction /// protein/// cell junctionbinding /// desmosome 219754_at 0.00594178 219754_at RBM41 RNA binding motif--- protein 41--- nucleotide binding--- /// nucleic acid binding /// RNA binding 219020_at 0.00610637 219020_at HS1BP3 HCLS1 binding--- protein 3 cell communicationprotein binding--- /// phosphoinositide binding 207061_at 0.00613022 207061_at ERN1 endoplasmic reticulum--- to nucleustranscription signaling ///nucleotide 1 mRNA processing bindingnuclear /// /// innermagnesium protein membrane modification ion binding /// endoplasmic process /// magnesium /// reticulum protein ion amino ///binding endoplasmic acid /// phosphorylation catalytic reticulum activity membrane/// /// protein endoribonuclease amino/// endoplasmic acid phosphorylationactivity reticulum /// endoribonuclease membrane /// apoptosis /// membraneactivity/// induction /// protein/// of integral apoptosis kinase to membraneactivity/// induction /// ///protein of integral apoptosis kinase to endoplasmic///activity response /// protein reticulumto unfolded serine/threonine membrane protein /// activationkinase activity of signaling /// protein protein serine/threonine activity involved kinase in unfolded activity ///protein protein response binding /// /// cell ATP cycle binding arrest /// /// ATP cell binding cycle arrest/// kinase /// endoplasmic activity /// transferase reticulum unfolded activity ///protein hydrolase response activity /// regulation/// endoribonuclease of transcription activity, /// protein producing amino 5'-phosphomonoesters acid autophosphorylation /// metal ion binding 201454_s_at 0.0061316 201454_s_at NPEPPS aminopeptidase--- puromycin sensitiveproteolysis aminopeptidasenucleus activity /// /// cytoplasm aminopeptidase /// cytosol activity /// protein binding /// peptidase activity /// metallopeptidase activity /// zinc ion binding /// hydrolase activity /// metal ion binding 209131_s_at 0.0061424 209131_s_at SNAP23 synaptosomal-associated--- protein,transport 23kDa /// post-Golgiprotein binding vesicle-mediatedplasma membrane transport enriched /// vesicle fraction targeting /// nucleus /// membrane/// cytoplasm fusion /// ///microsome protein transport/// plasma membrane /// plasma membrane /// plasma membrane /// membrane /// synaptosome /// extrinsic to membrane /// cell junction /// specific granule /// azurophil granule /// synapse 211691_x_at 0.00620953 211691_x_at ------enzyme inhibitor--- activity /// ornithine decarboxylase inhibitor activity 210034_s_at 0.0062156 210034_s_at RPL5 ribosomal proteinRibosomal_ProteinsRNA /// binding translation ///intracellular RNA /// translationbinding /// ///nucleus ///structural translational /// nucleolus constituent elongation /// ofcytoplasm ribosome /// ribosomal /// /// cytosol structural large /// subunitribosome constituent biogenesis /// of membrane ribosome ////// integralprotein bindingto membrane /// protein /// cytosolic binding large/// 5S ribosomal rRNA binding subunit /// ///rRNA ribonucleoprotein binding complex /// ribonucleoprotein complex 214347_s_at 0.00621857 214347_s_at DDC dopa decarboxylaseBiogenic_Amine_Synthesisamino acidcatalytic acid decarboxylase) and activity derivative--- /// aromatic-L-amino-acidmetabolic process /// circadian decarboxylase rhythm activity /// response /// aromatic-L-amino-acid to toxin /// carboxylic decarboxylase acid metabolic activity process /// /// aromatic-L-amino-acid catecholamine biosynthetic decarboxylase process activity /// protein binding /// lyase activity /// carboxy-lyase activity /// pyridoxal phosphate binding 206516_at 0.00622263 206516_at AMH anti-Mullerian ---hormone urogenital systemreceptor development bindingextracellular /// /// transforming Mullerian region duct ///growth regression extracellular factor ///beta regioncell-cell receptor /// signaling extracellular binding /// /// gonadal hormonespace ///mesoderm activityextracellular /// development growth space factor /// /// cytoplasm activitysex determination /// sex differentiation /// gonad development /// cell differentiation /// positive regulation of NF-kappaB transcription factor activity 216325_x_at 0.00625493 216325_x_at RTEL1 regulator of telomere--- elongationtelomere helicase maintenance 1nucleotide /// binding nucleobase,extracellular /// nucleic nucleoside, region acid /// binding nucleotidesoluble /// fraction DNA and binding nucleic /// nucleus ///acid ATP-dependent metabolic/// nucleus process DNA ///helicase DNA repair activity /// /// apoptosis ATP-dependent /// anti-apoptosis DNA helicase /// responseactivity /// to helicase DNA damage activity stimulus /// receptor /// regulation activity /// of receptordouble-strand activity break /// iron repair ion via binding homologous /// protein recombination binding /// ATP binding /// ATP binding /// ATP-dependent helicase activity /// hydrolase activity /// hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides /// metal ion binding /// iron-sulfur cluster binding 221835_at 0.00627177 221835_at DTX3 deltex homolog--- 3 (Drosophila)Notch signalingprotein pathway bindingcytoplasm /// zinc ion binding /// metal ion binding 203119_at 0.00628439 203119_at CCDC86 coiled-coil domain--- containinginterspecies 86 interaction--- betweennucleus organisms 222201_s_at 0.00629972 222201_s_at CASP8AP2 caspase 8 associated--- proteintranscription 2 ///transcription apoptosis ///corepressornucleus activation /// activitynucleus of caspase ////// death cytoplasmactivity receptor /// /// activation cytoplasmbinding of/// caspase protein activitybinding ////// cellprotein cycle binding /// signal /// transductioncaspase activator /// induction activity ///of apoptosiscaspase activator by extracellular activity signals/// apoptotic /// induction protease of activatorapoptosis activity via death /// domainapoptotic receptors protease /// activator induction activity of apoptosis /// identical via death protein domain binding receptors /// regulation of transcription 205524_s_at 0.00636007 205524_s_at HAPLN1 hyaluronan and--- proteoglycancell link adhesion protein binding1 /// hyaluronicextracellular acid regionbinding /// proteinaceous extracellular matrix /// proteinaceous extracellular matrix 220516_at 0.00636329 220516_at ZSCAN2 zinc finger and--- SCAN domaintranscription containing 2///nucleic regulation acid binding ofintracellular transcription, /// DNA /// binding nucleusDNA-dependent /// transcription /// multicellular factor activity organismal /// zinc development ion binding ////// metalspermatogenesis ion binding /// cell differentiation /// regulation of transcription 219447_s_at 0.00636332 219447_s_at SLC35C2 solute carrier family--- 35, membertransport C2 --- membrane /// integral to membrane 213198_at 0.00637845 213198_at ACVR1B activin A receptor,--- type IB G1/S transitionnucleotide of mitotic binding cellintegral cycle /// ///tomagnesium plasmain utero membrane embryonic ion binding ///development /// cell protein surface kinase /// /// hair membrane activity follicle ///development /// protein integral serine/threonine to /// membrane protein amino /// kinase activin acid activity phosphorylation receptor /// proteincomplex /// serine/threonine protein amino kinaseacid phosphorylation activity /// transmembrane /// induction ofreceptor apoptosis protein /// signal serine/threonine transduction kinase /// transmembrane activity /// transmembrane receptor protein receptor serine/threonine protein serine/threonine kinase signaling kinase pathway activity /// /// embryonic receptor developmentactivity /// transforming /// peptidyl-threonine growth factor phosphorylation beta receptor ///activity peptidyl-threonine /// protein binding phosphorylation /// protein binding/// negative /// ATP regulation binding of/// cell ATP growth binding /// /// positive kinase regulationactivity /// of activin activin receptor receptor activity, signaling type pathway I /// transferase /// positive activity regulation /// activin of activin receptor receptor activity signaling /// growth pathway factor /// bindingregulation /// ofmanganese transcription ion ///binding positive /// regulationubiquitin protein of erythrocyte ligase binding differentiation /// SMAD /// binding protein /// amino SMAD acid binding autophosphorylation /// metal ion binding /// activin binding /// activin binding 219045_at 0.0064217 219045_at RHOF ras homolog gene--- family, memberactin filament F (in ) nucleotideorganization binding ///intracellular small /// GTPaseGTPase /// cytoplasm activitymediated /// ///signal GTP cytoskeleton binding transduction /// cytoskeleton /// plasma membrane /// membrane 204976_s_at 0.00645214 204976_s_at AMMECR1 Alport syndrome,--- mental retardation,potassium midface ionvoltage-gated transport hypoplasia voltage-gatedpotassium and elliptocytosis channel potassium activitychromosomal channel /// protein complexregion binding gene /// membrane 1/// protein binding 214749_s_at 0.0065532 214749_s_at ARMCX6 /// LOC653354armadillo repeat--- containing,transport X-linked ///6 /// exocytosiscalcium similar ionto /// armadillobinding proteinmembrane /// repeattransport lipid /// bindingcontaining,integral ///to membranemetalX-linked ion 6binding /// cell junction /// cytoplasmic vesicle /// synapse 200060_s_at 0.00657602 200060_s_at RNPS1 RNA binding proteinmRNA_processing_Reactomedomainnucleotide mRNA binding catabolicnucleus /// ///nucleicprocess, nucleus acid nonsense-mediated /// binding nucleus /// ///RNA cytoplasm bindingdecay /// ////// nuclear RNAnuclear binding mRNA speck /// splicing, mRNA viabinding spliceosome /// protein /// bindingnuclear mRNA splicing, via spliceosome /// transcription /// mRNA processing /// RNA splicing /// RNA splicing 216662_at 0.00659258 216662_at MYO7B myosin VIIB ------nucleotide bindingcytoskeleton /// motor /// activity plasma /// membrane actin binding /// apical /// ATP plasma binding membrane /// myosin complex 201662_s_at 0.00661695 201662_s_at ACSL3 acyl-CoA synthetaseFatty_Acid_Degradation membernucleotide process 3 /// binding lipidmitochondrion metabolic /// magnesium process /// mitochondrial ion /// binding fatty acid ///outer metaboliccatalytic membrane activity process /// ///peroxisome /// acetate-CoA fatty acid /// biosynthetic endoplasmicligase activity process reticulum /// fatty-acyl-CoA /// learning/// microsome or synthase memory /// /// plasma activity Mitochondrial_fatty_acid_betaoxidation /// integral ligase activityto membrane /// long-chain-fatty-acid-CoA ligase activity /// protein binding /// ATP binding /// ligase activity 209654_at 0.00668688 209654_at KIAA0947 KIAA0947 ------202032_s_at 0.00671585 202032_s_at MAN2A2 mannosidase, ---alpha, class 2A,carbohydrate member 2 metaboliccatalytic activity processGolgi /// /// membranehydrolase carbohydrate activity,/// Golgi metabolic hydrolyzing apparatus process ///O-glycosyl ///membrane mannose compounds /// metabolic integral /// toprocessalpha-mannosidase membrane /// metabolic activity process /// mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity /// mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity /// zinc ion binding /// mannosidase activity /// hydrolase activity /// hydrolase activity, acting on glycosyl bonds /// hydrolase activity, hydrolyzing N-glycosyl compounds /// carbohydrate binding /// metal ion binding 209795_at 0.0067223 209795_at CD69 CD69 molecule------transmembraneintegral receptor to plasmaactivity membrane/// binding /// /// external calcium sideion binding of plasma /// membranesugar binding /// membrane /// integral to membrane 210599_at 0.00679866 210599_at ZNF614 zinc finger protein--- 614 transcription ///nucleic regulation acid binding ofintracellular transcription, /// DNA /// binding nucleusDNA-dependent /// zinc ion /// binding regulation /// metalof transcription ion binding 215838_at 0.0068031 215838_at LILRA5 leukocyte immunoglobulin-like--- immune receptor, response subfamilyreceptor activityA (withextracellular TM domain), region member /// membrane 5 /// integral to membrane 218511_s_at 0.00681922 218511_s_at PNPO pyridoxamine ---5'-phosphate pyridoxineoxidase biosyntheticpyridoxamine-phosphate process--- /// vitamin oxidase B6 metabolic activity /// process FMN binding /// oxidation /// oxidoreductase reduction activity /// oxidoreductase activity, acting on the CH-NH2 group of donors 203096_s_at 0.00683327 203096_s_at RAPGEF2 Rap guanine nucleotide--- exchangeMAPKKK factor cascade (GEF)signal /// 2 transducersignal transductionintracellular activity /// ////// guanyl-nucleotide plasmaintracellular membrane signaling exchange /// cascadeintegral factor to/// plasma smallactivity GTPase membrane /// calcium mediated /// ion membrane bindingsignal transduction /// /// protein membrane binding /// small /// GTPase Rap guanyl-nucleotide mediated signal exchangetransduction factor /// activitycAMP-mediated /// diacylglycerol signaling binding/// regulation /// Rap of GTPase small GTPase activator mediated activity signal transduction 203346_s_at 0.00689045 203346_s_at MTF2 metal response--- element binding--- transcriptionnucleic factor acid 2 bindingnucleus /// DNA binding /// protein binding /// zinc ion binding /// metal ion binding 213724_s_at 0.00689731 213724_s_at PDK2 pyruvate dehydrogenaseKrebs-TCA_Cycle metabolictwo-component2 processnucleus sensor /// glucose/// activity nucleolus metabolic /// nucleotide /// mitochondrion process binding /// glucose ////// proteinmitochondrion metabolic kinase process activity/// mitochondrial /// /// signal protein transduction matrix histidine /// kinasepyruvate /// peptidyl-histidine activity dehydrogenase /// pyruvate phosphorylation complex dehydrogenase (acetyl-transferring) kinase activity /// pyruvate dehydrogenase (acetyl-transferring) kinase activity /// protein binding /// ATP binding /// kinase activity /// transferase activity /// protein complex binding /// protein homodimerization activity /// protein heterodimerization activity 206428_s_at 0.00689899 206428_s_at ZNF143 zinc finger protein--- 143 transcription ///nucleic regulation acid binding ofintracellular transcription /// DNA /// binding fromnucleus RNA /// polymerasespecific RNA II polymerase promoter /// II regulationtranscription of transcriptionfactor activity from /// RNARNA polymerasepolymerase IIIIII transcriptionpromoter /// factorregulation activity of transcription/// zinc ion binding /// metal ion binding 217597_x_at 0.00690909 217597_x_at RAB40B RAB40B, member--- RAS oncogeneintracellular family signalingnucleotide cascade bindingplasma /// /// small membraneGTP GTPase binding /// mediated membrane signal transduction /// protein transport /// modification-dependent protein catabolic process 206250_x_at 0.00691356 206250_x_at AVPR1A arginine vasopressinGPCRDB_Class_A_Rhodopsin-like of systemicsignal transducer arterialendosome blood activity pressure /// /// plasma receptor by vasopressin membrane activity /// /// G-protein plasmamaternal membrane coupled aggressive receptor /// behavior integral activity ///to plasmapositive/// vasopressin membrane regulation receptor ///of natriuresis membrane activity /// /// positivevasopressin integral regulation to membranereceptor of ///activitysystemic Peptide_GPCRs C binding /// ///generation peptide ofhormone precursor binding metabolites /// V1A and vasopressin energy /// receptor response binding to stress /// signal transduction /// G-protein coupled receptor protein signaling pathway /// G-protein coupled receptor protein signaling pathway /// activation of phospholipase C activity /// elevation of cytosolic calcium ion concentration /// elevation of cytosolic calcium ion concentration /// negative regulation of female receptivity /// grooming behavior /// blood circulation /// positive regulation of cell proliferation /// response to organic substance /// response to inorganic substance /// positive regulation of heart rate /// positive regulation of glutamate secretion /// myotube differentiation /// calcium-mediated signaling /// telencephalon development /// positive regulation of cell growth /// positive regulation of prostaglandin biosynthe 218391_at 0.00694941 218391_at SNF8 SNF8, ESCRT-II--- complex subunit,transcription homolog ///RNA (S. regulation polymerasecerevisiae) ofnucleus transcription II transcription /// cytoplasm from factor RNA /// activitypolymeraseendosome membrane II promoter /// /// late transport endosome /// proteinmembrane transport /// regulation of transcription 207264_at 0.00697976 207264_at KDELR3 KDEL (Lys-Asp-Glu-Leu)--- endoplasmicRNA processing reticulumnucleotide /// protein protein binding retention nucleusretention /// ///nucleic in receptor nucleusER lumen acid 3 /// binding /// endoplasmic transport /// RNA /// reticulum binding protein /// transport/// RNA membrane binding /// vesicle-mediated ////// integralRNA helicase to membrane transport activity /// helicase activity /// receptor activity /// ATP binding /// ATP-dependent helicase activity /// RNA-dependent ATPase activity /// hydrolase activity /// ER retention sequence binding 221773_at 0.00701609 221773_at ELK3 ELK3, ETS-domain--- protein (SRFangiogenesis accessory ///DNA protein transcription binding 2) ///nucleus ///transcription regulation /// nucleus factor of transcription, /// activity nucleus /// /// DNA-dependenttranscription nucleolus /// factor mitochondrion /// signalactivity transduction /// /// transcription intracellular /// negative corepressor membrane-bounded regulation activity of ///transcription organelle protein binding /// wound /// purine-rich healing /// negative regulation regulatory of transcription element binding /// sequence-specific DNA binding 212780_at 0.00707488 212780_at SOS1 son of sevenlessIntegrin-mediated_cell_adhesion_KEGGDNA binding /// small ///intracellular GTPase guanyl-nucleotide mediated /// cytosol signal exchange /// transduction plasma factor membrane activity /// Ras /// ///protein Raspostsynaptic guanyl-nucleotide signal transduction density /// exchange ///cell Ras soma proteinfactor activity signal transduction/// Ras guanyl-nucleotide /// regulation exchangeof Rho protein factor signal activity transduction /// Rho guanyl-nucleotide /// positive regulation exchange of epidermal factor activity growth /// factorRho guanyl-nucleotide receptor signaling exchange pathway factor/// nerve activity growth /// Rhofactor GTPase receptor activator signaling activity pathway /// protein /// regulation binding of /// small protein GTPase binding mediated /// SH3 signal domain transduction binding 206222_at 0.00708854 206222_at TNFRSF10C tumor necrosis--- factor receptorapoptosis superfamily, /// signalreceptor member transduction activity 10c,plasma decoy /// transmembrane membrane without an /// intracellular integralreceptor to activitydomain plasma membrane /// membrane /// anchored to membrane 206061_s_at 0.0070973 206061_s_at DICER1 dicer 1, ribonucleasemRNA_processing_Reactome ///nucleotide RNA processing bindingintracellular ////// magnesiumstem /// cell cytoplasm maintenance ion binding /// RNA-induced ////// lungnucleic development acidsilencing binding complex /// /// embryonic RNA binding limb ///morphogenesis double-stranded /// RNARNA interference,binding /// double-stranded production of siRNA RNA ///binding RNA ///interference, helicase activity targeting /// ofnuclease mRNA foractivity destruction /// endonuclease /// gene silencing activity by/// RNAribonuclease /// pre-microRNA III activity processing /// ribonuclease /// embryonic III activity hindlimb /// protein morphogenesis binding /// /// ATP gene binding silencing /// ATP-dependent by miRNA, production helicase of activity miRNAs /// /// hydrolase branching activity morphogenesis /// manganese of a tube ion binding /// metal ion binding 213559_s_at 0.00710288 213559_s_at ZNF467 Zinc finger protein--- 467 transcription ///nucleic regulation acid binding ofintracellular transcription /// DNA /// binding nucleus /// protein binding /// zinc ion binding /// metal ion binding 219460_s_at 0.00710349 219460_s_at TMEM127 transmembrane--- protein 127------membrane /// integral to membrane 218441_s_at 0.00712236 218441_s_at RPAP1 RNA polymerase--- II associatedtranscription protein 1 DNA binding ///nucleus DNA-directed RNA polymerase activity /// transferase activity /// nucleotidyltransferase activity 210344_at 0.00713602 210344_at OSBPL7 oxysterol binding--- protein-liketransport 7 /// lipid--- transport ---/// steroid metabolic process 208361_s_at 0.00717807 208361_s_at POLR3D polymerase (RNA)RNA_transcription_Reactome polypeptide ///DNA transcription binding D, 44kDa ///nucleus fromDNA-directed RNA /// DNA-directed polymerase RNA polymerase III RNA promoter polymerase activity /// positive III complex regulation of interferon-beta production /// positive regulation of innate immune response 207745_at 0.00720316 207745_at CABP2 calcium binding--- protein 2 signal transductioncalcium ion bindingcytoplasm /// calcium /// Golgi ion apparatus binding /// plasma membrane /// membrane /// perinuclear region of cytoplasm 222064_s_at 0.00720756 222064_s_at AARSD1 alanyl-tRNA synthetase--- domaintranslation containing ///nucleotide alanyl-tRNA1 binding aminoacylationcytoplasm /// nucleic /// acid tRNA binding aminoacylation /// aminoacyl-tRNA ligase activity /// alanine-tRNA ligase activity /// ATP binding /// ligase activity, forming aminoacyl-tRNA and related compounds 204893_s_at 0.00724104 204893_s_at ZFYVE9 zinc finger, FYVETGF_Beta_Signaling_Pathway 9 ///receptor transforming activitycytoplasm growth /// protein factor /// bindingcytoplasm beta receptor /// ///protein early signaling binding endosome pathway /// serine-type/// ///cytosol transforming peptidase growth activity factor /// zinc beta ion receptor binding complex /// metal assembly ion binding /// SMAD protein complex assembly /// SMAD protein nuclear translocation 201623_s_at 0.00728223 201623_s_at DARS aspartyl-tRNA--- synthetase translation ///nucleotide translation binding ///soluble tRNA /// aminoacylationfraction nucleic ///acid cytoplasm binding for protein /// /// aminoacylase cytoplasm translation /// activity aspartyl-tRNA /// aminoacyl-tRNA aminoacylation ligase /// activity aspartyl-tRNA /// aspartate-tRNA aminoacylation ligase /// activity protein /// complex aspartate-tRNA assembly ligase activity /// protein binding /// ATP binding /// ligase activity 205461_at 0.00732292 205461_at RAB35 RAB35, member--- RAS oncogenecytokinesis family ///nucleotide transport binding/// plasmasmall /// GTPase membraneGTPase mediated activity /// plasma signal/// GTP membranetransduction binding /// /// phosphatidylinositol-4,5-bisphosphate/// coated protein pit localization/// membrane /// protein/// cell projectiontransport binding ///membrane endosome /// transport melanosome /// intercellular bridge /// clathrin-coated endocytic vesicle 206220_s_at 0.00733577 206220_s_at RASA3 RAS p21 proteinMAPK_CascadeGTPase /// activator signalintracellular transduction activity /// /// GTPase/// plasma intracellular activator membrane signaling activity /// membrane ///cascade zinc ion /// /// bindingregulation intrinsic /// to ofcalcium-release internal small GTPase side of channelmediatedplasma membraneactivity signal ///transduction metal ion binding 220582_at 0.00739433 220582_at ------202772_at 0.00740087 202772_at HMGCL 3-hydroxymethyl-3-methylglutaryl-CoenzymeSynthesis_and_Degradation_of_Keton_Bodies_KEGG nucleoside,acyl-CoA A lyase binding nucleotidemitochondrion /// nucleotideand nucleic /// bindingmitochondrial acid metabolic /// nucleic inner process acid membrane binding /// DNA /// replication DNAmitochondrial binding /// acyl-CoA/// matrix catalytic ///metabolic mitochondrialactivity process /// DNA-directed matrix /// metabolic /// mitochondrial DNA process polymerase /// matrix ketone activity body /// biosynthetichydroxymethylglutaryl-CoA process lyase activity /// hydroxymethylglutaryl-CoA lyase activity /// transferase activity /// nucleotidyltransferase activity /// lyase activity /// carboxylic acid binding /// metal ion binding 218977_s_at 0.00741006 218977_s_at TRNAU1AP tRNA selenocysteine--- 1 associatedselenocysteine protein nucleotide1 incorporation bindingnucleus /// selenocysteine/// ///nucleic nucleus acid ///incorporation binding cytoplasm /// RNA /// bindingtranslation /// protein binding 203958_s_at 0.00744598 203958_s_at ZBTB40 zinc finger and--- BTB domain transcriptioncontaining 40 ///nucleic regulation acid binding ofintracellular transcription /// DNA /// binding nucleus /// protein binding /// zinc ion binding /// metal ion binding 220932_at 0.00744665 220932_at ------210787_s_at 0.00745175 210787_s_at CAMKK2 calcium/calmodulin-dependent--- MAPKKK protein cascade kinasenucleotide /// kinase protein binding2, intracellular betaamino /// acid protein phosphorylation/// cytoplasmkinase activity /// /// protein protein amino serine/threonine acid phosphorylation kinase activity /// calcium-mediated /// calmodulin-dependent signaling /// protein regulation kinase of activity protein /// kinase protein activity tyrosine /// positivekinase activity regulation /// calciumof transcription ion binding /// protein/// calmodulin amino acid binding autophosphorylation /// calmodulin binding /// ATP binding /// kinase activity /// transferase activity 212293_at 0.00747729 212293_at HIPK1 homeodomain--- interacting proteintranscription kinase 1///nucleotide protein aminobindingnucleus acid /// phosphorylation///DNA nucleus binding /// /// nucleolus ///protein smoothened kinase/// cytoplasm activity signaling ////// pathwaycytoplasmprotein serine/threonine /// /// positive centrosome regulation kinase /// PML ofactivity cellbody proliferation /// nuclearprotein ///bindingspeck anterior/posterior /// protein binding pattern /// formation ATP binding /// DNA/// kinase damage activity response, /// transferase signal transduction activity by p53 class mediator resulting in induction of apoptosis /// regulation of transcription 218749_s_at 0.00748627 218749_s_at SLC24A6 solute carrier family--- 24 (sodium/potassium/calciumtransport /// ioncalcium transport ion exchanger), binding ///plasma sodium /// membrane memberantiporter ion transport 6 /// activity membrane /// calcium /// sodium /// ion integral transportion binding to membrane/// /// response lithium toion stimulus binding /// transmembrane transport 219526_at 0.00758021 219526_at C14orf169 chromosome 14--- open readingtranscription frame 169 ///--- chromatin modificationnucleus /// nucleoplasm /// regulation /// of nucleolus transcription 210681_s_at 0.00759051 210681_s_at USP15 ubiquitin specific--- peptidase 15ubiquitin-dependentcatalytic protein activity--- catabolic /// cysteine-type process /// endopeptidase modification-dependent activity /// protein ubiquitin catabolic thiolesterase process activity /// ubiquitin-specific protease activity /// ubiquitin-specific protease activity /// protein binding /// peptidase activity /// cysteine-type peptidase activity /// hydrolase activity 216698_x_at 0.00762893 216698_x_at LOC100290714similar /// LOC441453 to hCG2044651GPCRDB_Other olfactory coupledreceptor /// receptorreceptor, OR7E37P activity protein integralfamily /// /// OR7E47P olfactory 7,signaling to subfamily membrane receptor pathway A, /// member activity integral/// sensory 17/// to ///olfactory membrane perception olfactory receptor receptor, of smell activity family 7, subfamily E, member 18 pseudogene /// olfactory receptor, family 7, subfamily E, member 35 pseudogene /// olfactory receptor, family 7, subfamily E, member 37 pseudogene /// olfactory receptor, family 7, subfamily E, member 47 pseudogene 218337_at 0.00763243 218337_at FAM160B2 family with sequence--- similarity--- 160, member--- B2 --- 212718_at 0.00764001 212718_at PAPOLA poly(A) polymerasemRNA_processing_ReactomemRNAnucleotide splicing, via binding spliceosomenucleus /// ///RNA nucleus /// binding transcription /// /// nucleus RNA /// binding /// mRNA nucleolus /// polyadenylation polynucleotide /// cytoplasm ///adenylyltransferase mRNA/// cytoplasm processing activity/// RNA /// 3'-end ATP bindingprocessing /// transferase/// RNA polyadenylation activity /// nucleotidyltransferase activity 208855_s_at 0.00765408 208855_s_at STK24 serine/threonine--- kinase 24 (STE20protein homolog,amino nucleotideacid yeast) phosphorylation bindingcytoplasm /// ///protein signal kinase transduction activity /// protein kinase activity /// protein serine/threonine kinase activity /// ATP binding /// kinase activity /// transferase activity 218743_at 0.00765662 218743_at CHMP6 chromatin modifying--- proteintransport 6 /// proteinprotein transportbindingendosome /// protein /// N-terminus endomembrane binding system /// membrane /// anchored to membrane /// late endosome membrane 201901_s_at 0.00770051 201901_s_at YY1 YY1 transcription--- factor transcription ///nucleic regulation acid binding ofintracellular transcription, /// DNA /// binding nucleusDNA-dependent /// /// transcription nucleus /// ///regulation transcriptionfactor activity of transcription factor /// transcription complex from ///RNA factorplasma polymerase activity membrane ///II promoter transcription /// nuclear /// anterior/posterior coactivatormatrix /// PcG activity protein pattern /// complextranscription formation /// corepressor regulation activity of transcription /// protein /// binding camera-type /// zinc eye ion morphogenesis binding /// zinc ion binding /// specific transcriptional repressor activity /// metal ion binding 204435_at 0.00772527 204435_at NUPL1 nucleoporin like--- 1 transport /// proteinnucleocytoplasmic transportnucleus /// transporter mRNA /// nuclear transport activity pore /// /// transmembrane proteinmembrane binding transport /// intracellular protein transmembrane transport 202172_at 0.00776341 202172_at VEZF1 vascular endothelial--- zinc fingerangiogenesis 1 ///nucleic endothelial acid bindingintracellular cell development /// DNA /// binding nucleus /// transcription /// specific RNA /// regulation polymerase of IItranscription transcription from factor RNA activity polymerase /// zinc II ionpromoter binding /// /// cellular metal iondefense binding response /// regulation of transcription 215875_at 0.00779436 215875_at ------203959_s_at 0.00780832 203959_s_at ZBTB40 zinc finger and--- BTB domain transcriptioncontaining 40 ///nucleic regulation acid binding ofintracellular transcription /// DNA /// binding nucleus /// protein binding /// zinc ion binding /// metal ion binding 203566_s_at 0.00785126 203566_s_at AGL amylo-1, 6-glucosidase,Glycogen_Metabolism metaboliccatalytic activity processnucleus /// /// glycogen glycogen/// cytoplasm debranching biosynthetic /// cytosol enzyme process /// inclusionactivity /// metabolic /// body 4-alpha-glucanotransferase ///process isoamylase complex activity /// amylo-alpha-1,6-glucosidase activity /// amylo-alpha-1,6-glucosidase activity /// protein binding /// transferase activity /// transferase activity, transferring glycosyl groups /// hydrolase activity /// hydrolase activity, acting on glycosyl bonds /// polysaccharide binding /// polyubiquitin binding /// cation binding 202743_at 0.00785532 202743_at PIK3R3 phosphoinositide-3-kinase,--- regulatoryinsulin receptor subunitprotein signaling 3 (gamma) binding pathwayphosphoinositide /// protein /// insulin binding 3-kinasereceptor /// kinase signalingcomplex activity pathway /// 1-phosphatidylinositol-3-kinase activity /// phosphoinositide 3-kinase regulator activity /// 1-phosphatidylinositol-3-kinase regulator activity 210813_s_at 0.0078997 210813_s_at XRCC4 X-ray repair complementing--- in defective utero embryonic repairDNA in bindingdevelopmentChinese /// condensedhamster DNA /// binding pro-Bcells chromosome 4cell /// differentiationprotein /// binding nucleus /// /// ///DNA protein nucleus ligation binding /// /// nucleus DNA/// protein repair /// cytosol ///binding double-strand /// /// DNA-dependent protein break C-terminus repair protein ///binding kinase-DNA double-strand /// ligase ligase breakactivity 4 complex repair /// /// double-strand DNA-dependent break protein repair kinase-DNA via nonhomologous ligase 4 complex end joining /// DNA/// double-strand ligase IV complex break repair via nonhomologous end joining /// double-strand break repair via nonhomologous end joining /// double-strand break repair via nonhomologous end joining /// DNA recombination /// response to DNA damage stimulus /// central nervous system development /// response to X-ray /// response to X-ray /// response to ionizing radiation /// response to gamma radiation /// provirus integration /// initiation of viral infection /// T cell differentiation in the thymus /// V(D)J recombination /// immunoglobulin V(D)J recombination /// negative regulation of neuron apoptosis /// isotype switching /// positive regulation of fibroblast proliferation /// positive regulation of neurogenesis /// DNA ligation during DNA repair /// positive regulation of ligase activity 213443_at 0.00791612 213443_at TRADD TNFRSF1A-associatedApoptosis /// inductionsignal transducer of apoptosiscytoplasm activity /// /// induction/// cytoplasm receptor of apoptosisactivity /// cytosol /// /// protein/// induction cytoskeleton binding of apoptosis /// /// protein receptor /// binding signal complex transduction/// intermediate /// ///Apoptosis_GenMAPP /// kinase activation binding of pro-apoptotic/// identical protein gene productsbinding ////// moleculartumor necrosis adaptor factor-mediated activity /// death signaling domain pathway binding /// positive regulation /// of Apoptosis_KEGG cascade /// positive regulation of I-kappaB kinase/NF-kappaB cascade /// positive regulation of hair follicle development 218894_s_at 0.00791714 218894_s_at MAGOHB mago-nashi homolog--- B (Drosophila)mRNA processingRNA ///binding transportnucleus /// RNA splicing /// mRNA transport 209054_s_at 0.00793301 209054_s_at WHSC1 Wolf-Hirschhorn--- syndrome candidatetranscription 1 ///DNA anatomical binding /// nucleusstructure protein /// morphogenesisbinding nucleus /// /// methyltransferase cytoplasm /// chromatin modificationactivity /// zinc /// regulationion binding of /// transcription transferase activity /// histone-lysine N-methyltransferase activity /// metal ion binding 206829_x_at 0.00793541 206829_x_at ZNF430 zinc finger protein--- 430 transcription ///nucleic regulation acid binding ofintracellular transcription, /// DNA /// binding nucleusDNA-dependent /// zinc ion /// binding regulation /// metalof transcription ion binding 212745_s_at 0.00795694 212745_s_at BBS4 Bardet-Biedl syndrome--- 4 microtubule cytoskeletonmicrotubule organization motorpericentriolar activity /// /// materialmicrotubule binding /// /// cytoplasmcytoskeleton protein binding /// organizationcentrosome /// dynactin ////// centrosomebindingneural tube /// alpha-tubulin///closure /// neural /// binding cytoskeleton tube /// closure beta-tubulin /// /// plasma retina binding membranehomeostasis /// /// cilium retina /// homeostasis microtubule ///basal heart body looping /// membrane /// spermatid /// nonmotile development primary /// spermatid cilium /// developmentmotile secondary /// visual cilium perception /// motile ///secondary sensory ciliumperception /// centriolar of smell satellite/// sensory /// perceptionBBSome /// of cell smell projection /// dendrite /// cilium development membrane /// ///dendrite cilium developmentmembrane /// regulation of lipid metabolic process /// regulation of lipid metabolic process /// striatum development /// striatum development /// hippocampus development /// hippocampus development /// cerebral cortex development /// cerebral cortex development /// adult behavior /// adult behavior /// melanosome transport /// regulation of cytokinesis /// cytokinesis during cell cycle /// protein localization in organelle /// protein localization in organelle /// microtubule anchoring at centrosome /// sensory cilium assembly /// sensory cilium assembly /// cilium assembly /// fat cell differentiation /// fat cell differentiation /// photorece 210768_x_at 0.00803599 210768_x_at TMCO1 transmembrane--- and coiled-coil--- domains 1--- endoplasmic reticulum /// Golgi apparatus /// membrane /// integral to membrane 218180_s_at 0.00803636 218180_s_at EPS8L2 EPS8-like 2 ------receptor activitycytoplasm /// kinase activity 41397_at 0.0080801 41397_at ZNF821 zinc finger protein--- 821 transcription ///DNA regulation binding ///ofintracellular transcriptionzinc ion binding /// nucleus /// metal ion binding 212997_s_at 0.00812215 212997_s_at TLK2 tousled-like kinase--- 2 regulation of chromatinnucleotide assembly bindingnucleus /// or /// proteindisassembly nucleus kinase /// /// activitynucleus protein /// amino protein acid serine/threonine phosphorylation kinase /// protein activity amino /// protein acid phosphorylation serine/threonine /// kinase response activity to DNA /// proteindamage serine/threonine stimulus /// cell kinasecycle /// activity intracellular /// protein signaling binding cascade /// ATP /// binding chromatin /// ATPmodification binding /// kinase activity /// transferase activity 205959_at 0.00815248 205959_at MMP13 matrix metallopeptidaseMatrix_Metalloproteinases to hypoxia 3)fibronectin /// proteolysis bindingextracellular /// /// metalloendopeptidase proteolysis region /// /// proteinaceous metabolic activity process extracellular /// metalloendopeptidase /// response matrix to/// mechanical fibrillar activity collagen stimulus /// calcium /// ///extracellular boneion binding mineralization space /// peptidase /// extracellular/// collagen activity catabolicspace /// metallopeptidase /// processlysosome /// /// receptor activity Golgi apparatus internalization/// zinc ion /// binding intercellular /// embryonic /// zinc canaliculus ion hindlimb binding morphogenesis /// hydrolase activity /// peptide /// metal catabolic ion bindingprocess /// /// calcium-dependent response to estrogen protein stimulus binding /// cartilage/// low-density development lipoprotein receptor binding 211332_x_at 0.00815915 211332_x_at HFE hemochromatosis--- antigen processingiron ion and binding presentationcytoplasm /// protein of /// peptide bindingearly endosomeantigen via /// MHC plasma class membraneI /// protein /// complex integral assembly to plasma /// membrane transport ////// membraneion transport /// /// integral iron ion to transportmembrane /// /// iron cytoplasmic ion transport vesicle /// cellular/// MHC iron class ion I proteinhomeostasis complex /// ///receptor-mediated apical part of cell endocytosis /// apical part/// immune of cell /// response basal part /// offemale cell /// pregnancy perinuclear /// regioncellular of response cytoplasm to ///iron recycling ion starvation endosome /// antigen processing and presentation /// hormone biosynthetic process /// iron ion homeostasis 212389_at 0.00819561 212389_at SBF1 SET binding factor--- 1 protein amino proteinacid dephosphorylation tyrosine/serine/threoninenucleus /// /// integral spermatogenesis phosphataseto membrane /// activity dephosphorylation /// phosphatase activity 216771_at 0.00822326 216771_at ------207753_at 0.00824174 207753_at ZNF304 zinc finger protein--- 304 transcription ///nucleic regulation acid binding ofintracellular transcription, /// DNA /// binding nucleusDNA-dependent /// zinc ion /// binding regulation /// metalof transcription ion binding 220742_s_at 0.00827625 220742_s_at NGLY1 N-glycanase 1--- glycoprotein catabolicpeptide-N4-(N-acetyl-beta-glucosaminyl)asparagine processcytoplasm /// glycoprotein /// cytoplasm catabolic process amidase activity /// protein binding /// protein binding /// zinc ion binding /// hydrolase activity /// metal ion binding 204399_s_at 0.0082763 204399_s_at EML2 echinoderm microtubule--- associatedproteolysis protein ///serine-type visual like 2 perception endopeptidasecytoplasm /// sensory /// activity microtubule perception /// protein /// of microtubulesound binding associated complex /// intracellular membrane-bounded organelle 205300_s_at 0.00829911 205300_s_at SNRNP35 small nuclear ---ribonucleoproteinmRNA 35kDa processing (U11/U12)nucleotide /// RNA binding splicingnucleus /// ///nucleic nucleus acid /// binding spliceosomal /// RNA complexbinding 214030_at 0.00832433 214030_at CRYBG3 beta-gamma crystallin--- domain--- containing sugar3 binding --- 203111_s_at 0.00832834 203111_s_at PTK2B PTK2B protein--- tyrosine kinaseMAPKKK 2 beta cascadenucleotide /// angiogenesis bindingnucleus /// /// ///protein oocyte cytoplasm kinase maturation /// activity cytoplasm /// /// response protein /// cytoskeleton totyrosine hypoxia kinase /// proteinplasma activity complexmembrane /// protein assembly /// tyrosine focal /// adhesion kinase protein activity ///amino cell /// acidcortex non-membrane phosphorylation /// postsynaptic spanning /// density protein protein /// amino membrane tyrosine acid phosphorylation kinase /// axon activity /// growth ////// non-membraneoxygen cone ///and membrane reactive spanning oxygen raft protein /// species perinuclear tyrosine metabolic kinaseregion process activityof cytoplasm /// /// apoptosis signal transducer /// response activity to stress /// signal /// response transducer to osmoticactivity stress/// protein /// actin binding filament /// protein organization binding /// /// cell ATP adhesion binding /// signalkinase transductionactivity /// transferase /// signal complex activity ///assembly protein /// complex signal bindingcomplex /// assembly 3-phosphoinositide-dependent /// epidermal growth factor protein receptor kinase signaling binding pathway /// elevation of cytosolic calcium ion concentration /// positive regulation of cell proliferation /// positive regulation of cell proliferation /// response to mechanical stimulus /// response to hormone stimulus /// response to glucose stimulus /// response to lithium ion /// response to organic nitrogen /// glial cell proliferation /// cell differentiation /// negative regulation of ossification /// positive regulation of cell growth /// positive regulation of cell migration /// neuron projection development /// activati 209579_s_at 0.00834538 209579_s_at MBD4 methyl-CpG binding--- domainDNA protein repair 4 ///DNA DNA binding repair //////chromatin base-excisionsatellite ///DNA nucleus bindingrepair ////// /// nucleusresponse catalytic /// to activity nucleus DNA damage /// /// endodeoxyribonuclease nucleolus stimulus /// /// cytoplasm DNA damage activity response, /// protein signal binding transduction /// hydrolase resulting activity in induction of apoptosis /// response to radiation /// depyrimidination 221830_at 0.00837144 221830_at RAP2A RAP2A, member--- of RAS oncogenesignal transductionfamily nucleotide /// signal bindingintracellular transduction /// GTPase /// /// plasmaactivity small membraneGTPase/// GTPase mediated ///activity membrane signal /// protein transduction /// membrane binding /// GTP binding 201121_s_at 0.00839363 201121_s_at PGRMC1 progesterone receptor--- membrane--- componentreceptor 1 activitynucleus /// steroid /// nucleolus binding ////// endoplasmicsteroid binding reticulum /// protein /// endoplasmicbinding /// lipid reticulum binding /// /// microsome heme binding /// cell surface /// membrane /// integral to membrane 219856_at 0.00840505 219856_at C1orf116 chromosome 1--- open reading--- frame 116 receptor activitycytoplasm /// cytoplasm 204608_at 0.00843834 204608_at ASL argininosuccinateSmooth_muscle_contraction /// nucleotideargininosuccinate bindingnucleus metabolic/// ///catalytic cytoplasm process activity ////// /// plasmaresponse DNA-directed membrane to hypoxia RNA /// ///polymerase DNA kidney polymerase development activity III /// complex DNA-directed/// liver /// development membrane RNA polymerase /// transcription activity /// transcriptionargininosuccinate from lyaseRNA polymeraseactivity /// argininosuccinateIII promoter /// arginine lyase activity biosynthetic /// receptor process activity /// arginine /// calcitonin catabolic receptor process activity /// /// lyase reaction activity /// response to nutrient /// locomotory behavior /// cellular amino acid biosynthetic process /// post-embryonic development /// ammonia assimilation cycle /// arginine biosynthetic process via ornithine /// response to peptide hormone stimulus /// cellular metabolic process /// response to steroid hormone stimulus /// response to glucocorticoid stimulus /// response to cAMP 211042_x_at 0.00844546 211042_x_at MCAM melanoma cell--- adhesion moleculecell adhesion ///protein cell adhesionbindingplasma /// anatomical membrane structure /// membrane morphogenesis /// integral to membrane 212725_s_at 0.008456 212725_s_at TUG1 taurine upregulated--- 1 (non-protein--- coding)------219967_at 0.00852385 219967_at MRM1 mitochondrial ---rRNA methyltransferaseRNA processing 1 homologRNA binding (S. cerevisiae) ///mitochondrion methyltransferase activity /// RNA methyltransferase activity /// transferase activity 214938_x_at 0.00854198 214938_x_at HMGB1 high-mobility ---group box 1 DNA unwindingDNA during binding replication ///condensed DNA /// binding DNA chromosome repair /// protein /// ///base-excision binding condensed /// transcription repair,chromosome DNA ligationfactor /// nucleus binding /// base-excision /// /// nucleus DNA bending /// repair, chromosome activity DNA ligation /// nucleolus /// DNA recombination /// chromatin organization /// regulation of transcription from RNA polymerase II promoter /// anti-apoptosis /// signal transduction /// negative regulation of transcriptional preinitiation complex assembly /// negative regulation of transcriptional preinitiation complex assembly 208997_s_at 0.008548 208997_s_at UCP2 uncoupling proteinElectron_Transport_Chain protonto superoxidebinding carrier) /// transportmitochondrion /// transport /// mitochondrial /// mitochondrial inner membrane transport /// mitochondrialproton transport inner /// membranetransmembrane /// membrane transport /// integral to membrane 209146_at 0.00858225 209146_at SC4MOL sterol-C4-methylCholesterol_Biosynthesis metabolicC-4 methylsterol processendoplasmic /// oxidase fatty acid activity reticulum biosynthetic /// C-4/// endoplasmic processmethylsterol /// steroid reticulum oxidase biosynthetic activity /// endoplasmic /// process C-4 methylsterol reticulum /// steroid membrane oxidasemetabolic activity ///process plasma /// ///iron membrane lipid ion biosyntheticbinding /// ///membrane oxidoreductaseprocess ////// integralsterol activity biosynthetic to membrane process /// integral /// oxidation to membrane reduction 204621_s_at 0.00858559 204621_s_at NR4A2 nuclear receptorNuclear_Receptors A, to member hypoxiaDNA binding 2/// neuron ///nucleus DNA migration binding/// nucleus /// /// response transcription /// cytoplasm to amphetamine factor activity /// /// transcription steroid hormone /// regulation receptor of activity transcription, /// receptor DNA-dependent activity /// ligand-dependent/// induction of apoptosis nuclear receptor/// response activity to stress /// ligand-dependent /// signal transduction nuclear /// receptor signal activitytransduction /// protein /// nervous binding system /// protein development binding /// zincadult ion locomotory binding /// behavior transcription /// post-embryonic activator activity development /// transcription /// response regulator to inorganic activity /// substance protein homodimerization/// gene expression activity /// death /// sequence-specific/// response to insecticide DNA binding /// central /// metal nervous ion binding system /// projection protein heterodimerization neuron axonogenesis activity /// central nervous system neuron differentiation /// neuron differentiation /// cellular response to extracellular stimulus /// cellular response to extracellular stimulus /// regulation of dopamine metabolic process /// dopamine biosynthetic process /// dopamine metabolic process /// neuron maturation /// positive regulation of catalytic activity /// negative regulation of caspase activity /// negative regulation of neuron apoptosis /// regulation of respiratory gaseous exchange /// regulation of transcription /// positive regulation of tra 208830_s_at 0.00858657 208830_s_at SUPT6H suppressor of ---Ty 6 homolog nucleobase,(S. cerevisiae) nucleoside,transcription nucleotide factornucleus activity and /// nucleusnucleic /// transcription acid metabolic elongation process regulator /// chromatin activity remodeling /// RNA binding /// transcription /// protein /// binding regulation /// hydrolase of transcription, activity, DNA-dependent acting on ester ///bonds regulation of transcription from RNA polymerase II promoter /// regulation of transcription 221798_x_at 0.00859558 221798_x_at ------203344_s_at 0.00862045 203344_s_at RBBP8 retinoblastoma--- binding proteincell 8cycle checkpointprotein ///binding G1/Snucleus transition /// nucleus of mitotic cell cycle /// blastocyst hatching /// DNA repair /// regulation of transcription from RNA polymerase II promoter 218900_at 0.00864896 218900_at CNNM4 cyclin M4 --- transport /// ion--- transport ///plasma visual membrane perception /// /// membrane biomineral ///formation integral /// to responsemembrane to stimulus 206954_at 0.00866847 206954_at WIT1 Wilms tumor upstream--- neighborcell proliferation 1 ------213729_at 0.00869707 213729_at PRPF40A PRP40 pre-mRNAmRNA_processing_Reactome homologprotein /// A RNAbinding (S. cerevisiae)splicingnucleus /// protein /// nuclear binding speck 200658_s_at 0.00870888 200658_s_at PHB prohibitin --- DNA replicationprotein /// signal binding transductionnucleus /// transcription /// ///nucleoplasm negative activator regulation /// activitymitochondrion of /// cell transcription proliferation /// mitochondrion repressor /// negative /// activity mitochondrial regulation of inner transcription membrane /// ///histone mitochondrial deacetylation inner /// membrane regulation /// of integral apoptosis to ///plasma regulation membrane of transcription /// membrane 217551_at 0.00872494 217551_at LOC441453 similar to olfactory--- receptor,G-protein family 7, coupledsubfamilyolfactory receptor A, receptormember proteinintegral activity17 signaling to membrane pathway 218474_s_at 0.00876184 218474_s_at KCTD5 potassium channel--- tetramerisationpotassium domain ionvoltage-gated transport containing /// 5 nucleusinterspeciespotassium /// channelcytoplasm interaction activity /// between voltage-gated /// protein organisms binding potassium /// protein channel binding complex /// membrane 218080_x_at 0.00876783 218080_x_at FAF1 Fas (TNFRSF6)--- associated factorapoptosis 1 /// cytoplasmicprotein binding sequesteringnucleus /// protein /// ofnucleus binding NF-kappaB /// /// nuclear protein /// cell envelope kinase death regulator/// /// regulation cytoplasm activity of /// cell /// cytosol adhesionprotein /// kinase CD95/// positive bindingdeath-inducing regulation /// protein signaling of domainprotein complex specificcomplex ///binding assembly perinuclear /// ///heat regulationregion shock of protein cytoplasm of protein binding catabolic /// NF-kappaB process ///binding positive regulation of apoptosis /// positive regulation of apoptosis /// proteasomal ubiquitin-dependent protein catabolic process 212368_at 0.0087699 212368_at ZNF292 zinc finger protein--- 292 transcription ///DNA regulation binding ///ofintracellular transcriptionzinc ion binding /// nucleus /// metal ion binding 206737_at 0.00877115 206737_at WNT11 wingless-type Wnt_signaling family,signal member /// transducer Wnt 11 receptorextracellular activity signaling region pathway, /// proteinaceous calcium modulating extracellular pathway matrix /// multicellular organismal development /// anatomical structure morphogenesis /// Wnt receptor signaling pathway 204701_s_at 0.00878341 204701_s_at STOML1 stomatin (EPB72)-like--- 1 --- sterol carrier activitymembrane /// integral to membrane 213459_at 0.00878997 213459_at RPL37A ribosomal protein--- L37a translation ///structural translational constituent intracellularelongation of ribosome /// cytosol /// ///protein ribosome binding /// ///ribonucleoprotein zinc ion binding complex /// metal ion binding 209503_s_at 0.00879376 209503_s_at PSMC5 (prosome,Proteasome_Degradation subunit, fromnucleotide RNA ATPase, polymerase bindingproteasome 5 /// IItranscription promoter complex /// ///cofactor negative proteasome activity regulation complex /// receptor of transcription/// nucleus binding /// ////// nucleus proteinprotein /// bindingcatabolic nucleolus /// process protein /// cytoplasm /// binding anaphase-promoting /// cytoplasmATP binding /// complex-dependent/// cytosolProteasome_Degradation /// ubiquitin-dependent peptidase activity /// protein hydrolase catabolic activity process /// ATPase /// negative activity regulation /// nucleoside-triphosphatase of programmed cell death activity /// /// proteasomal thyrotropin-releasing ubiquitin-dependent hormone receptorprotein catabolic binding process /// positive regulation of gene-specific transcription /// negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle /// positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle 211423_s_at 0.00890708 211423_s_at SC5DL sterol-C5-desaturaseCholesterol_BiosynthesisC-5 process sterol homolog, /// desaturase fattyendoplasmic S. acid cerevisiae)-like activity biosynthetic reticulum /// iron process /// ion membrane binding /// steroid /// /// oxidoreductase biosyntheticintegral to membrane process activity /// /// lipid lathosterol biosynthetic oxidase process activity /// sterol biosynthetic process /// oxidation reduction 218609_s_at 0.00890794 218609_s_at NUDT2 nudix (nucleoside--- diphosphatenucleobase, linked moiety nucleoside,nucleotide X)-type nucleotidebinding motif--- 2 /// and bis(5'-nucleosyl)-tetraphosphatase nucleic acid metabolic process /// (asymmetrical) induction of apoptosis activity /// bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity /// GTP binding /// bis(5'-nucleosyl)-tetraphosphatase activity /// bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity /// hydrolase activity 201483_s_at 0.00892532 201483_s_at SUPT4H1 suppressor of ---Ty 4 homolog negative1 (S. cerevisiae) regulationtranscription of transcription factornucleus activity from/// nucleus RNA/// protein polymerase /// nucleus binding II /// promoter/// nucleoplasm negative /// transcriptionchromatin remodeling elongation /// factor transcription activity /// /// positive regulation transcription of transcription, elongation DNA-dependent factor activity /// /// regulation positive oftranscription transcription elongation from RNA factor polymerase activity II/// promoter zinc ion ///binding RNA ///elongation metal ion from binding RNA ///polymerase protein heterodimerization II promoter /// regulation activity of transcription /// positive regulation of transcription /// positive regulation of transcription from RNA polymerase II promoter 201567_s_at 0.00896199 201567_s_at GOLGA4 golgi autoantigen,--- golgin subfamilyvesicle-mediated a, 4 nucleotide transport bindingcytoplasm /// Golgi apparatus /// trans-Golgi network /// membrane /// extrinsic to membrane 206040_s_at 0.00896619 206040_s_at MAPK11 mitogen-activated--- protein kinaseprotein 11 amino nucleotideacid phosphorylation bindingnucleoplasm /// ///protein response /// kinasecytosol to activitystress /// /// signal protein transduction serine/threonine /// protein kinase kinase activity cascade /// protein /// Ras serine/threonine protein signal transductionkinase activity /// MAP kinase activity /// MAP kinase activity /// protein binding /// protein binding /// ATP binding /// MP kinase activity /// kinase activity /// transferase activity 201152_s_at 0.00897682 201152_s_at MBNL1 muscleblind-like--- (Drosophila)regulation of alternativenucleic acid nuclear bindingnucleus mRNA /// /// RNA nucleussplicing, binding /// via ///cytoplasm spliceosome double-stranded /// ///cytoplasm in uteroRNA binding embryonic /// zincdevelopment ion binding /// /// mRNA metal splice ion bindingsite selection /// nervous system development /// muscle organ development /// skeletal muscle tissue development /// embryonic limb morphogenesis /// myoblast differentiation 203490_at 0.00902061 203490_at ELF4 E74-like factor--- 4 (ets domainnatural transcription killer cellDNA factor) proliferation binding ///nucleus ///transcription natural /// nucleus killer factor cell /// activity proliferationPML body /// transcription /// NK T cell factor proliferation activity ////// proteinNK T cell binding proliferation /// transcription /// transcription activator /// activity regulation /// transcriptionof transcription, activator DNA-dependent activity /// /// sequence-specific regulation of transcription, DNA binding DNA-dependent /// regulation of transcription /// positive regulation of transcription from RNA polymerase II promoter /// positive regulation of transcription from RNA polymerase II promoter 212896_at 0.00903757 212896_at SKIV2L2 superkiller viralicidic--- activitymRNA 2-like processing 2 (S. cerevisiae)nucleotide /// RNA binding splicingnucleus /// ///nucleic spliceosomal acid binding complex /// helicase /// nucleolus activity /// protein binding /// ATP binding /// ATP-dependent helicase activity /// hydrolase activity /// hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 47105_at 0.00904804 47105_at DUS2L dihydrouridine--- synthase 2-like,tRNA SMM1 processing homologRNA /// binding (S.metabolic cerevisiae) ///intracellular double-strandedprocess /// /// oxidation cytoplasm RNA reductionbinding /// endoplasmic /// catalytic reticulum activity /// oxidoreductase activity /// tRNA dihydrouridine synthase activity /// FAD binding 202101_s_at 0.00908895 202101_s_at RALB v-ral simian leukemia--- viral oncogenesignal transduction homolognucleotide B/// (ras signal binding related;intracellular transduction /// GTP GTPase binding /// /// plasmaactivity small protein) membraneGTPase/// protein mediated ///binding membrane signal /// GTP transduction binding /// /// GTP Ras binding protein signal transduction 202466_at 0.0091419 202466_at POLS polymerase (DNA--- directed) sigmaDNA replicationDNA /// bindingdouble-strand ///nucleus DNA-directed break /// nucleus repair DNA /// polymerase cell cycle /// activity sister chromatid/// transferase cohesion activity /// ///mitosis nucleotidyltransferase /// mitotic chromosome activity condensation /// SMC protein /// responsebinding to drug /// cell division 200891_s_at 0.00923108 200891_s_at SSR1 signal sequence--- receptor, alphacotranslationalreceptor protein activitytargetingendoplasmic /// to signal membrane sequencereticulum /// positivebinding/// endoplasmic regulation/// calcium reticulum of ion cell binding proliferation /// endoplasmic reticulum /// membrane /// integral to membrane /// integral to membrane 200077_s_at 0.0092323 200077_s_at OAZ1 ornithine decarboxylaseNucleotide_Metabolism biosyntheticenzyme inhibitor process--- activity /// protein binding /// ornithine decarboxylase inhibitor activity /// ornithine decarboxylase inhibitor activity 204800_s_at 0.00926794 204800_s_at DHRS12 dehydrogenase/reductase--- (SDRmetabolic family) process membercatalytic /// 12 oxidation activity--- /// reduction binding /// oxidoreductase activity 221700_s_at 0.00929807 221700_s_at UBA52 ubiquitin A-52DNA_replication_Reactome /// fusionstructural translational product constituent intracellularelongation1 of ribosome/// /// protein nucleus /// modification protein/// nucleus binding process/// cytoplasm/// protein/// cell /// cyclebinding cytosol /// /// axon /// transcription ribosome guidance /// ///regulator cytosolic protein activity ubiquitination small ribosomal /// subunitER-associated /// ribonucleoprotein/// proteinDNA_replication_Reactome /// long-term strengthening of neuromuscular junction /// proteasomal ubiquitin-dependent protein catabolic process /// positive regulation /// Proteasome_Degradation regulation of synaptic plasticity /// Ribosomal_Proteins /// Ribosomal_Proteins 213832_at 0.00930011 213832_at KCND3 potassium voltage-gated--- channel,transport Shal-related /// ionion transportchannel subfamily, activity ///plasma potassiummember /// membrane voltage-gated 3 ion transport /// voltage-gated ion /// channel potassium activity potassium ion ///transport voltage-gatedchannel /// complex transmembrane potassium /// voltage-gated channel transport activity potassium /// A-type channel (transient complex outward) /// membrane potassium /// integral channel to activity membrane /// A-type /// sarcolemma (transient ///outward) neuron potassium projection channel /// cell somaactivity /// potassium channel activity /// protein binding /// zinc ion binding /// potassium ion binding /// metal ion binding 210396_s_at 0.00933195 210396_s_at BOLA2 /// LOC440354bolA homolog /// LOC595101 ---2 (E. coli) /// aminoPI-3-kinase-related acid transportamino kinase acid/// transmembranetransmembrane SMG-1membrane pseudogene /// transport transporterintegral /// PI-3-kinase-relatedto membraneactivity /// kinase kinase activity SMG-1 pseudogene 205327_s_at 0.00933827 205327_s_at ACVR2A activin A receptor,--- type IIA gastrulation withnucleotide mouth formingbindingcytoplasm ///second magnesium /// /// plasma positive ion membrane bindingregulation /// /// ofprotein integral protein kinase toamino plasma activity acid membrane phosphorylation /// protein /// serine/threoninemembrane /// protein /// aminointegral kinase acid toactivity membranephosphorylation /// transmembrane /// inhibin-betaglycan-ActRII /// transmembrane receptor protein receptor complex serine/threonine protein serine/threonine kinase activity kinase /// signalingtransmembrane pathway receptor /// transmembrane protein serine/threonine receptor protein kinase serine/threonine activity /// receptor kinase signaling signaling protein pathway serine/threonine /// spermatogenesis kinase ///activity determination /// receptor of activityleft/right /// symmetry transforming /// mesoderm growth factor development beta receptor /// male activity gonad /// proteindevelopment binding /// /// anterior/posterior ATP binding /// coreceptorpattern formation activity ////// positivekinase activity regulation /// activinof bone receptor mineralization activity, /// type BMP II signaling /// transferase pathway activity /// BMP /// signalingactivin receptor pathway activity /// regulation /// activin of receptorBMP signaling activity pathway /// growth /// activinfactor bindingreceptor /// signaling manganese pathway ion binding /// positive /// protein regulation self-association of activin receptor /// metal signaling ion binding pathway /// activin/// sperm binding ejaculation /// activin /// penilebinding erection /// inhibin /// positivebeta-A binding regulation /// inhibinof erythrocyte beta-A bindingdifferentiation /// inhibin /// positive beta-B bindingregulation of osteoblast differentiation /// embryonic skeletal system development /// regulation of nitric-oxide synthase activity /// Sertoli cell proliferation 204672_s_at 0.00936105 204672_s_at ANKRD6 ankyrin repeat--- domain 6 --- protein binding--- 215233_at 0.00936404 215233_at JMJD6 jumonji domain--- containing 6blood vessel developmentreceptor activity ///nucleus kidney /// iron /// development ion nucleus binding /// //////plasma proteintranscription membrane binding /// /// mRNA oxidoreductase processing activity/// apoptosis /// oxidoreductase /// cell surface activity, receptor acting linked on signal single transduction donors with ///incorporation multicellular of organismalmolecular oxygen, development incorporation /// heart of development two atoms of /// oxygen RNA splicing /// histone /// chromatindemethylase modification activity (H3-R2 /// peptidyl-lysine specific) /// histonehydroxylation demethylase to 5-hydroxy-L-lysine activity (H4-R3 ///specific) cell differentiation /// identical protein/// lung binding development /// metal /// ionT cell binding differentiation /// peptidyl-lysine in the thymus 5-dioxygenase /// macrophage activity activation /// apoptotic cell clearance /// recognition of apoptotic cell /// regulation of transcription /// regulation of nuclear mRNA splicing, via spliceosome /// erythrocyte development /// oxidation reduction /// retina development in camera-type eye /// histone H3-R2 demethylation /// histone H4-R3 demethylation 206730_at 0.00939064 206730_at GRIA3 glutamate receptor,--- ionotrophic,regulation AMPA of3 receptorreceptor recyclingactivitymembrane /// /// ionotropic transport fraction glutamate/// /// transport plasma receptor ///membrane ion activity transport /// /// plasma ///alpha-amino-3-hydroxy-5-methyl-4-isoxazole glutamate membrane signaling /// postsynaptic pathway /// density response /// membraneto propionate lithium ion/// selective integral glutamate to membrane receptor /// cell activity junction /// ///ion asymmetricchannel activity synapse /// extracellular-glutamate-gated /// synaptic cleft /// terminal ionbutton channel /// dendritic activity spine/// protein /// dendritic binding shaft/// PDZ /// domainperikaryon binding /// protein complex /// synapse /// postsynaptic membrane 216582_at 0.00942683 216582_at POM121L2 POM121 membrane--- glycoprotein-like--- 2 (rat)------AFFX-CreX-5_at0.00942783 AFFX-CreX-5_at------DNA recombinationDNA binding /// DNA ---integration 218546_at 0.00943057 218546_at C1orf115 chromosome 1--- open reading--- frame 115 --- membrane /// integral to membrane 211241_at 0.0094829 211241_at ANXA2P3 annexin A2 pseudogene--- 3 ------208626_s_at 0.00949467 208626_s_at VAT1 vesicle amine ---transport proteinmetabolic 1 homolog processDNA (T. ///californica)binding cell growth ///nucleus catalytic /// /// oxidation activityintegral reduction ///to membranebinding /// zinc ion binding /// oxidoreductase activity 219154_at 0.00949671 219154_at TMEM120B transmembrane--- protein 120B------membrane /// integral to membrane 219136_s_at 0.00952174 219136_s_at LMF1 lipase maturation--- factor 1 protein secretion--- endoplasmic reticulum /// membrane /// integral to membrane 218962_s_at 0.00955173 218962_s_at TMEM168 transmembrane--- protein 168------membrane /// integral to membrane /// transport vesicle 219757_s_at 0.00957708 219757_s_at C14orf101 chromosome 14--- open reading--- frame 101 --- membrane /// integral to membrane 219993_at 0.00957964 219993_at SOX17 SRY (sex determining--- regionangiogenesis Y)-box 17 ///DNA vasculogenesis binding ///nucleus beta-catenin /// transcription/// nucleus binding /// /// negative transcription regulation factor of bindingWnt receptor signaling pathway /// protein destabilization /// regulation of transcription /// protein stabilization 204089_x_at 0.00959042 204089_x_at MAP3K4 mitogen-activatedG13_Signaling_Pathway of kinaseMAPKKnucleotide 4activity binding--- /// protein /// magnesium amino acid ion phosphorylation binding /// protein /// responsekinase activity to stress /// protein/// JNK serine/threoninecascade kinase activity /// MAP kinase kinase kinase activity /// MAP kinase kinase kinase activity /// ATP binding /// kinase activity /// transferase activity /// metal ion binding 221240_s_at 0.00959749 221240_s_at B3GNT4 UDP-GlcNAc:betaGal--- beta-1,3-N-acetylglucosaminyltransferaseprotein amino galactosyltransferaseacid glycosylationGolgi apparatus activity4 ////// transferasemembrane activity/// integral /// transferaseto membrane activity, transferring glycosyl groups 44617_at 0.0096064 44617_at OGFOD2 2-oxoglutarate--- and iron-dependentoxidation oxygenase reductioniron ion domain binding containing--- /// protein 2 binding /// oxidoreductase activity /// oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen /// oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen /// L-ascorbic acid binding /// metal ion binding 213751_at 0.00966301 213751_at LRRC68 leucine rich repeat--- containing--- 68 ------217411_s_at 0.00966673 217411_s_at RREB1 ras responsive--- element bindingtranscription protein 1 ///nucleic regulation acid binding ofintracellular transcription, /// DNA /// binding nucleusDNA-dependent /// /// zinc nucleus ion /// binding ///transcription cytoplasm /// transcription from /// nuclear RNA activatorpolymerase body /// activity nuclear II promoter /// speck metal /// ion Ras binding protein signal transduction /// multicellular organismal development /// regulation of transcription 217247_at 0.00967323 217247_at ------208641_s_at 0.00973337 208641_s_at RAC1 ras-related C3G13_Signaling_Pathway /// 1nucleotide (rhocell motionfamily, binding ///intracellularsmall inflammatory /// GTP GTPase binding /// membrane activityresponse protein /// Rac1)/// fractionGTPase hyperosmotic ///activity cytoplasm ///response protein /// cytosol/// binding cytoskeleton /// /// plasma GTP organization binding membrane /// GTP /// cellmembranebinding adhesion /// ///enzyme /// cytoplasmic cell bindingadhesion /// G13_Signaling_Pathwayvesicle binding///cascade extrinsic /// smallto plasma GTPase membrane mediated /// signal lamellipodium transduction /// melanosome/// axon guidance /// response to wounding /// anatomical structure /// morphogenesisIntegrin-mediated_cell_adhesion_KEGG of hydrogen peroxide metabolic process /// positive regulation of lamellipodium assembly /// dendrite development /// cerebral cortex radially oriented cell /// migrationIntegrin-mediated_cell_adhesion_KEGG olfactory bulb interneuron precursor migration /// lamellipodium assembly /// actin filament polymerization /// regulation of cell migration /// positive regulation /// Wnt_signaling /// ruffle organization /// ruffle organization /// positive regulation of Rho protein signal transduction /// positive regulation of phosphoinositide 3-kinase activity /// negative regulation of receptor-mediated endocytosis /// localization within membrane /// regulation of respiratory burst 207726_at 0.00975775 207726_at ESRRB estrogen-relatedNuclear_ReceptorsembryonicDNA bindingdevelopment ///nucleus transcription /// trophectodermal factor activity cellular /// steroidmorphogenesis hormone /// receptor trophectodermal activity /// cell receptor proliferation activity /// /// embryonic ligand-dependent placenta nuclear development receptor /// activity transcription /// ligand-dependent /// regulation of nuclear transcription, receptor DNA-dependent activity /// steroid /// stembinding cell /// maintenance zinc ion binding /// regulation /// sequence-specific of transcription DNA binding /// metal ion binding 220486_x_at 0.00977566 220486_x_at TMEM164 transmembrane--- protein 164------membrane /// integral to membrane 205550_s_at 0.00979153 205550_s_at BRE brain and reproductive--- organ-expressedDNA repair /// (TNFRSF1Aperoxisome double-strand modulator) targetingnuclear break ubiquitinsequencerepair /// ligaseapoptosisbinding complex /// /// tumor response /// necrosisnucleus to DNA ///factor nucleus damage receptor /// stimulus cytoplasm binding /// /// response/// protein cytoplasm bindingto DNA /// damage///BRCA1-A polyubiquitin stimulus complex binding/// /// signal BRISC transduction complex /// response to ionizing radiation /// chromatin modification /// G2/M transition DNA damage checkpoint /// positive regulation of DNA repair /// positive regulation of anti-apoptosis 207384_at 0.0098368 207384_at PGLYRP1 peptidoglycan ---recognition proteinimmune 1 responseprotein /// bindingimmuneextracellular /// response bacterial ///region binding peptidoglycan /// /// extracellular N-acetylmuramoyl-L-alanine catabolic region process /// detection amidase of bacteriumactivity /// /// peptidoglycan defense response receptor to bacteriumactivity /// /// peptidoglycan innate immune binding response /// regulation of circadian sleep/wake cycle, sleep /// defense response to Gram-positive bacterium 218246_at 0.00984148 218246_at MUL1 mitochondrial ---E3 ubiquitin ligasemitochondrial 1 ubiquitin-proteinfission /// apoptosismitochondrion ligase /// activityinduction /// ///mitochondrion of signal apoptosis transducer ////// activationmitochondrial activity of/// caspase proteinouter membrane activitybinding ////// /// activationprotein peroxisome binding of JUN /// /// kinaseperoxisome zinc ionactivity binding /// /// membrane ///protein ligase ubiquitination /// activity integral /// toidentical /// membrane modification-dependent protein /// bindingintegral ///to mitochondrialmetalprotein ion catabolic binding outer process membrane /// negative regulation of cell growth /// positive regulation of I-kappaB kinase/NF-kappaB cascade /// mitochondrion localization 221315_s_at 0.00984854 221315_s_at FGF22 fibroblast growth--- factor 22 fibroblast growthgrowth factor factor receptor extracellularactivity signaling region pathway /// extracellular/// cell differentiation region /// /// nucleolus /// Golgi apparatus /// cell surface 217009_at 0.00985025 217009_at PGK2 phosphoglycerateGlycolysis_and_Gluconeogenesis /// glycolysisnucleotide /// binding phosphorylationcytoplasm /// phosphoglycerate /// cytosol /// phosphorylation kinase activity /// phosphoglycerate kinase activity /// phosphoglycerate kinase activity /// ATP binding /// ATP binding /// kinase activity /// transferase activity 205983_at 0.00987165 205983_at DPEP1 dipeptidase 1 Eicosanoid_Synthesisprotein bindingplasma /// peptidase membrane activity /// membrane /// metalloexopeptidase /// anchored to activity membrane /// metalloexopeptidase /// cell projection activity /// metallopeptidase activity /// dipeptidyl-peptidase activity /// zinc ion binding /// hydrolase activity /// dipeptidase activity /// metal ion binding 214535_s_at 0.00991909 214535_s_at ADAMTS2 ADAM metallopeptidase--- withproteolysis thrombospondin ///metalloendopeptidase spermatogenesis type 1 motif,extracellular 2/// collagen activity region ///fibril ///metalloendopeptidase organization proteinaceous /// extracellularlung activity development ///matrix peptidase /// /// collagen extracellular activity catabolic /// matrix metallopeptidase process /// skin activity development /// metallopeptidase /// protein maturation activity /// by zinc peptide ion bindingbond cleavage /// hydrolase activity /// metal ion binding 215245_x_at 0.00995405 215245_x_at FMR1 fragile X mental--- retardation transport1 /// mRNARNA binding transport ///soluble RNA bindingfraction ////// mRNAnucleus binding /// nucleoplasm /// protein /// binding nucleolus /// nucleolus /// cytoplasm /// cytoplasm /// polysomal ribosome 213540_at 0.00998542 213540_at HSD17B8 hydroxysteroid--- (17-beta) dehydrogenasesteroid biosynthetic catalytic8 process activity membrane/// /// estrogen estradiol fraction biosynthetic 17-beta-dehydrogenase /// mitochondrion process /// estrogen/// activity mitochondrial biosynthetic /// estradiol envelope process 17-beta-dehydrogenase /// /// mitochondrial metabolic process matrix activity ////// androgen///plasma estradiol membrane metabolic 17-beta-dehydrogenase process /// lipid biosyntheticactivity /// retinoid-X process /// receptor oxidation activity reduction /// binding /// oxidoreductase activity /// thyroid hormone receptor coactivator activity /// vitamin D receptor binding /// retinoic acid receptor binding /// thyroid hormone receptor binding /// protein heterodimerization activity /// testosterone 17-beta-dehydrogenase activity 205619_s_at 0.00999177 205619_s_at MEOX1 mesenchyme homeobox--- 1 somite specificationDNA binding /// regulation ///nucleus chromatin of transcription, binding /// DNA-dependent transcription factor /// multicellular activity /// transcriptionorganismal development regulator activity /// multicellular /// sequence-specific organismal DNA development binding /// regulation of transcription /// positive regulation of transcription from RNA polymerase II promoter go cellular component term nucleus /// cytoplasm nucleus /// nucleus /// cytoplasm nucleus /// nucleus /// cytoplasm /// cytoplasm intracellular /// nucleus /// nucleus histone deacetylase complex /// nucleus /// nucleus transcription factor complex /// transcription factor complex nucleoplasm /// cytoplasm /// cytosol mitochondrion membrane /// integral to membrane cell-cell junction /// cell junction /// desmosome extracellular region nucleus /// nucleus /// nucleus /// nucleolus /// nucleolus /// cytoplasm /// cytoplasm /// cytoplasm intracellular /// nucleus /// nucleus nucleus /// nucleus /// nucleus cytoplasm /// cytoskeleton /// microtubule /// microtubule associated complex /// microtubule associated complex /// cytoplasmic microtubule membrane fraction /// endoplasmic reticulum /// endoplasmic reticulum membrane /// integral to plasma membrane /// membrane /// integral to membrane nucleus /// cytoplasm /// cytoplasm /// cytoplasm /// mitochondrion /// Golgi apparatus /// Golgi apparatus nucleus /// nucleus /// cytoplasm integrin complex /// integrin complex /// membrane /// integral to membrane nucleus /// nucleus /// nucleus /// nucleoplasm cytoplasm /// cytosol cullin-RING ubiquitin ligase complex nucleus /// nucleus /// nucleus /// nucleolus /// cytoplasm soluble fraction /// nucleus /// nucleus /// nucleoplasm /// cytoplasm /// cytoplasm /// cytoplasm /// spindle /// cytosol /// cytoskeleton /// plasma membrane /// plasma membrane /// plasma membrane /// membrane /// lamellipodium cytoplasm /// mitochondrion nucleus /// nucleus /// nucleolus /// cytoskeleton /// integrator complex nucleus /// adherens junction /// cell-cell adherens junction /// cell junction /// protein complex extracellular region /// soluble fraction membrane /// integral to membrane cytoplasm /// cytosol /// membrane /// integral to membrane /// sarcoplasmic reticulum membrane /// calcium channel complex membrane /// integral to membrane membrane /// integral to membrane nucleus /// chromatin silencing complex /// nucleolus /// nucleolus /// nucleolus organizer region /// rDNA heterochromatin intracellular /// nucleus /// nucleus /// intracellular membrane-bounded organelle Golgi membrane /// membrane fraction /// Golgi apparatus /// membrane /// integral to membrane /// integral to membrane intracellular /// cytoplasm /// RNA-induced silencing complex intracellular /// nucleus membrane /// integral to membrane /// integral to membrane plasma membrane /// integral to plasma membrane /// membrane /// integral to membrane plasma membrane /// membrane /// integral to membrane soluble fraction /// nucleus /// nucleus /// cytoplasm /// mitochondrion /// mitochondrion /// mitochondrial intermembrane space /// microsome plasma membrane /// plasma membrane /// cell-cell junction /// cell-cell adherens junction /// membrane /// integral to membrane /// apical junction complex mitochondrion plasma membrane /// plasma membrane /// coated pit /// membrane /// cell projection membrane /// melanosome /// intercellular bridge /// clathrin-coated endocytic vesicle intracellular /// nucleus /// nucleus /// intracellular membrane-bounded organelle nucleus /// nucleolus nucleus /// nucleoplasm /// mitochondrion /// mitochondrion /// mitochondrial inner membrane /// mitochondrial inner membrane /// integral to plasma membrane /// membrane extracellular region /// proteinaceous extracellular matrix /// proteinaceous extracellular matrix /// extracellular space /// cell surface cytoplasm /// cytoplasm /// autophagic vacuole /// autophagic vacuole /// pre-autophagosomal structure membrane /// pre-autophagosomal structure membrane /// intracellular membrane-bounded organelle membrane fraction /// membrane fraction /// /// plasma membrane /// plasma membrane /// integral to plasma membrane /// postsynaptic density /// membrane /// integral to membrane /// axon /// dendrite /// axolemma /// asymmetric synapse /// presynaptic membrane /// cell soma /// postsynaptic membrane /// presynaptic active zone intracellular /// nucleus /// nucleus intracellular /// nucleus /// cytoplasm /// cytoplasm /// Golgi apparatus /// intracellular membrane-bounded organelle nucleus /// nucleolus /// nucleolus /// cytoplasm extracellular region /// extracellular region /// proteinaceous extracellular matrix /// collagen type VII /// basement membrane /// basement membrane nucleus /// nucleus /// cytoplasm cytoplasm /// cytoplasm /// autophagic vacuole /// autophagic vacuole /// pre-autophagosomal structure membrane /// pre-autophagosomal structure membrane /// intracellular membrane-bounded organelle endoplasmic reticulum /// endoplasmic reticulum /// ribosome /// membrane /// integral to membrane extracellular region /// secretory granule membrane /// integral to membrane /// integral to membrane mitochondrion /// mitochondrial inner membrane /// peroxisome /// peroxisome /// peroxisomal membrane /// peroxisomal membrane /// integral to peroxisomal membrane /// membrane /// integral to membrane plasma membrane /// membrane /// integral to membrane /// integral to membrane kinetochore /// condensed chromosome kinetochore /// nuclear envelope /// cytoplasm /// centrosome /// spindle /// cytoskeleton /// microtubule /// microtubule associated complex /// axon /// cell leading edge /// neurofilament cytoskeleton nucleus /// nucleus extracellular region /// plasma membrane /// membrane /// integral to membrane ubiquitin ligase complex /// nuclear ubiquitin ligase complex /// nucleus /// nucleus /// BRCA1-A complex /// BRISC complex cytoplasm /// mitochondrion /// peroxisome /// peroxisome /// peroxisomal membrane acrosomal vesicle /// soluble fraction /// lysosome /// membrane membrane /// integral to membrane intracellular /// nucleus /// nucleus nucleus /// nucleus histone deacetylase complex /// chromatin /// heterochromatin /// nucleus /// nucleus /// nucleus /// nucleus /// cytoplasm soluble fraction /// nucleus /// nucleolus /// cytoplasm /// cytoplasm /// cytoplasm /// centrosome /// cytosol membrane fraction /// voltage-gated calcium channel complex /// protein serine/threonine phosphatase complex /// neuron projection extracellular region /// extracellular region /// proteinaceous extracellular matrix /// collagen type VII /// basement membrane /// basement membrane nuclear ubiquitin ligase complex /// nucleus /// nucleus /// cytoplasm /// cytoplasm /// BRCA1-A complex /// BRISC complex membrane fraction /// cytoplasm /// endoplasmic reticulum /// Golgi apparatus /// Golgi apparatus /// membrane /// integral to membrane nucleus /// cytoplasm /// cytosol voltage-gated potassium channel complex /// membrane integral to plasma membrane /// integral to plasma membrane /// membrane /// integral to membrane endoplasmic reticulum /// translocon complex /// membrane /// integral to membrane extracellular space /// plasma membrane /// membrane /// anchored to membrane /// anchored to plasma membrane Golgi apparatus /// membrane /// integral to membrane nucleus /// cytoplasm intracellular /// nucleus /// nucleus /// nucleolus /// intracellular membrane-bounded organelle centrosome /// spindle /// microtubule /// HAUS complex intracellular /// cytoplasm /// Golgi apparatus /// spindle /// microtubule /// microtubule /// tight junction /// cell junction /// cell soma /// dendritic shaft integral to plasma membrane /// membrane /// integral to membrane extracellular region /// proteinaceous extracellular matrix /// basement membrane /// basal lamina /// endoplasmic reticulum /// laminin-11 complex nucleus /// nucleus /// nucleus /// nucleus /// cytoplasm /// cytoplasm /// cytoplasm /// cytoplasm /// plasma membrane intracellular /// cytoplasm /// /// endomembrane system /// membrane /// lamellipodium /// growth cone /// filamentous actin /// cell projection /// neuron projection /// cell soma extracellular region /// nucleus /// nucleus /// transcription factor complex cytoplasm /// Golgi apparatus /// plasma membrane /// plasma membrane /// voltage-gated potassium channel complex /// membrane /// integral to membrane intracellular /// nucleus /// cytoplasm extracellular region intracellular /// nucleus /// nucleus Golgi membrane /// endoplasmic reticulum /// Golgi apparatus /// membrane /// integral to membrane intracellular /// cytoplasm /// cytosol nucleus /// nucleus /// nucleus /// nucleolus /// cytoplasm soluble fraction /// cytosol /// protein complex nucleus /// nucleus /// nucleolus /// cytoplasm /// cytoplasm /// centrosome /// PML body /// nuclear speck pericentriolar material /// cytoplasm /// cytoplasm /// centrosome /// centrosome /// cytoskeleton /// membrane /// integral to membrane /// nonmotile primary cilium /// centriolar satellite nuclear envelope /// nuclear envelope /// lysosome /// lysosome /// endosome /// endoplasmic reticulum /// endoplasmic reticulum /// integral to plasma membrane /// integral to plasma membrane /// membrane /// integral to membrane /// integral to membrane /// perinuclear region of cytoplasm /// perinuclear region of cytoplasm nucleus /// nucleolus /// mitochondrion /// mitochondrion /// mitochondrial matrix /// pyruvate dehydrogenase complex cytoskeleton /// cytoskeleton /// F-actin capping protein complex /// F-actin capping protein complex /// actin cytoskeleton chromatin /// nucleus /// nucleus /// nucleus /// cytoskeleton extracellular region /// extracellular region /// proteinaceous extracellular matrix membrane fraction /// lysosome /// lysosome /// lysosomal membrane /// endosome /// late endosome /// late endosome /// plasma membrane /// plasma membrane /// membrane /// integral to membrane /// platelet dense granule membrane /// platelet dense granule membrane extracellular region /// proteinaceous extracellular matrix /// basement membrane /// cytoplasm /// early endosome /// sarcolemma /// melanosome /// protein complex /// perinuclear region of cytoplasm nucleus /// mitochondrion /// mitochondrial matrix /// mitochondrial matrix /// cytosol /// actin filament /// mitochondrial nucleoid nucleus /// nucleus /// transcription factor TFIID complex /// transcription factor TFIID complex /// transcription factor TFIID complex /// nucleolus /// cytoplasm /// transcription factor TFTC complex

cytoplasm /// mitochondrion /// peroxisome /// peroxisome membrane /// integral to membrane /// integral to membrane extracellular region /// plasma membrane /// integral to plasma membrane /// membrane /// integral to membrane /// extrinsic to plasma membrane cytoplasm /// plasma membrane nucleus /// nucleolus cytoplasm /// lysosome /// endosome /// membrane /// extrinsic to membrane /// HOPS complex nucleus /// cytoplasm /// heterotrimeric G-protein complex /// membrane /// extrinsic to membrane chromatin /// nucleus /// nucleus /// nucleus /// cytoskeleton cytoplasm /// clathrin coat of endocytic vesicle /// clathrin-coated vesicle /// cytoplasmic vesicle intracellular /// membrane fraction /// plasma membrane /// plasma membrane /// membrane /// membrane raft endoplasmic reticulum /// Golgi apparatus /// membrane /// integral to membrane Golgi membrane /// Golgi apparatus /// trans-Golgi network /// membrane /// integral to membrane /// intrinsic to Golgi membrane mitochondrion /// mitochondrion /// mitochondrial inner membrane /// mitochondrial matrix /// mitochondrial matrix /// plasma membrane exocyst /// cytoplasm /// microtubule organizing center /// cytosol /// plasma membrane /// membrane /// extrinsic to membrane /// centriolar satellite nucleus /// Piccolo NuA4 histone acetyltransferase complex /// NuA4 histone acetyltransferase complex mitochondrion /// mitochondrion /// mitochondrial nucleoid membrane fraction /// plasma membrane /// integral to plasma membrane /// membrane /// integral to membrane chromatin /// heterochromatin /// nucleus /// nucleus /// cytoplasm /// nuclear speck nucleus /// plasma membrane /// plasma membrane /// coated pit /// membrane /// extrinsic to membrane intracellular /// nucleus nucleus /// nucleus /// cytoplasm /// perinuclear region of cytoplasm /// perinuclear region of cytoplasm extracellular region nucleus /// cytoplasm /// endoplasmic reticulum /// endoplasmic reticulum /// microsome /// Golgi apparatus /// membrane /// integral to membrane /// intracellular membrane-bounded organelle membrane fraction /// integral to plasma membrane /// membrane /// integral to membrane /// outer membrane cytoplasm /// plasma membrane /// postsynaptic density /// membrane /// cell junction /// synapse /// postsynaptic membrane nucleus /// nucleus /// cytoplasm /// cytoplasm cytoplasm /// cytoplasm endoplasmic reticulum /// endoplasmic reticulum membrane /// membrane /// integral to membrane extracellular region /// extracellular region nucleus /// nucleoplasm /// cytoplasm /// nuclear matrix endoplasmic reticulum /// endoplasmic reticulum /// Golgi apparatus /// membrane /// integral to membrane nucleus /// nucleus /// nucleolus /// cytoskeleton /// integrator complex endoplasmic reticulum /// endoplasmic reticulum /// ribosome /// membrane /// integral to membrane membrane /// integral to membrane plasma membrane /// plasma membrane /// cilium /// membrane /// integral to membrane /// integral to membrane endoplasmic reticulum /// endoplasmic reticulum lumen /// endoplasmic reticulum lumen nucleus /// nucleus /// nucleus /// nucleolus /// mitochondrion /// intracellular membrane-bounded organelle internal side of plasma membrane nucleus /// cytoplasm /// F-actin capping protein complex /// melanosome plasma membrane /// membrane /// integral to membrane /// integral to membrane nucleus /// adherens junction /// cell-cell adherens junction /// cell junction /// protein complex plasma membrane /// integral to plasma membrane /// membrane /// membrane /// integral to membrane /// integral to membrane integral to plasma membrane /// membrane /// membrane /// integral to membrane exocyst /// cytoplasm /// microtubule organizing center /// cytosol /// plasma membrane /// membrane /// extrinsic to membrane /// centriolar satellite membrane fraction /// plasma membrane /// membrane /// integral to membrane /// platelet dense granule membrane podosome /// nucleus /// cytoplasm /// cytoplasm /// cytoskeleton /// plasma membrane /// plasma membrane /// actin cytoskeleton /// membrane /// cell projection /// costamere intracellular /// nucleus /// cytoplasm intracellular /// nucleus mitochondrion /// ribosome /// ribonucleoprotein complex nucleus /// cytoplasm spindle pole /// cell /// soluble fraction /// nucleus /// nucleus /// nucleoplasm /// cytoplasm /// cytoplasm /// cytosol /// cytosolic part soluble fraction /// cytoplasm /// cytoplasm /// cytosol lysosomal membrane /// microtubule organizing center /// microtubule organizing center /// membrane /// integral to membrane /// integral to membrane /// integral to membrane /// cytoplasmic membrane-bounded vesicle /// cytoplasmic membrane-bounded vesicle /// ATP-binding cassette (ABC) transporter complex soluble fraction /// nucleus /// nuclear envelope /// nuclear envelope lumen /// cytoplasm /// cytosol /// membrane /// nuclear matrix /// nuclear matrix /// extrinsic to membrane /// dendrite /// nuclear membrane /// sarcolemma endoplasmic reticulum /// endoplasmic reticulum /// membrane /// integral to membrane histone deacetylase complex /// nucleus /// nucleus chromatin /// nucleus /// nucleus /// nucleus /// cytoskeleton nucleus /// nucleus /// axon Golgi membrane /// membrane fraction /// Golgi apparatus /// membrane /// integral to membrane /// integral to membrane nucleus /// cytoplasm /// cytoskeleton /// focal adhesion /// focal adhesion /// cell junction intracellular /// Golgi stack /// Golgi-associated vesicle nucleus /// nuclear speck intracellular /// membrane fraction /// Golgi apparatus /// cytosol /// membrane /// extrinsic to membrane cytoplasm /// cytosol cytoplasm /// cytoskeleton /// plasma membrane /// adherens junction /// actin cytoskeleton /// membrane /// cell junction membrane fraction /// plasma membrane /// plasma membrane /// membrane /// integral to membrane /// apical plasma membrane /// intrinsic to membrane nucleus /// cytoplasm /// endosome /// late endosome /// cytosol /// cytosol endosome /// membrane /// extrinsic to membrane Golgi apparatus /// Golgi apparatus /// membrane /// integral to membrane /// Golgi cisterna membrane cytoplasm /// axon extracellular region /// specific granule cell-cell junction /// cell junction /// desmosome nuclear inner membrane /// endoplasmic reticulum /// endoplasmic reticulum membrane /// endoplasmic reticulum membrane /// membrane /// integral to membrane /// integral to endoplasmic reticulum membrane nucleus /// cytoplasm /// cytosol plasma membrane enriched fraction /// nucleus /// cytoplasm /// microsome /// plasma membrane /// plasma membrane /// plasma membrane /// membrane /// synaptosome /// extrinsic to membrane /// cell junction /// specific granule /// azurophil granule /// synapse intracellular /// nucleus /// nucleolus /// cytoplasm /// cytosol /// ribosome /// membrane /// integral to membrane /// cytosolic large ribosomal subunit /// ribonucleoprotein complex /// ribonucleoprotein complex extracellular region /// extracellular region /// extracellular space /// extracellular space /// cytoplasm extracellular region /// soluble fraction /// nucleus /// nucleus nucleus /// nucleus /// cytoplasm /// cytoplasm extracellular region /// proteinaceous extracellular matrix /// proteinaceous extracellular matrix intracellular /// nucleus membrane /// integral to membrane integral to plasma membrane /// cell surface /// membrane /// integral to membrane /// activin receptor complex intracellular /// cytoplasm /// cytoskeleton /// cytoskeleton /// plasma membrane /// membrane voltage-gated potassium channel complex /// membrane membrane /// integral to membrane /// cell junction /// cytoplasmic vesicle /// synapse nucleus /// nucleus /// nucleus /// cytoplasm /// nuclear speck cytoskeleton /// plasma membrane /// apical plasma membrane /// myosin complex mitochondrion /// mitochondrial outer membrane /// peroxisome /// endoplasmic reticulum /// microsome /// plasma membrane /// membrane /// integral to membrane

Golgi membrane /// Golgi apparatus /// membrane /// integral to membrane integral to plasma membrane /// external side of plasma membrane /// membrane /// integral to membrane intracellular /// nucleus extracellular region /// membrane /// integral to membrane intracellular /// plasma membrane /// integral to plasma membrane /// membrane /// membrane nucleus /// nucleolus /// mitochondrion /// mitochondrion /// mitochondrial matrix /// pyruvate dehydrogenase complex intracellular /// nucleus plasma membrane /// membrane endosome /// plasma membrane /// plasma membrane /// integral to plasma membrane /// membrane /// integral to membrane nucleus /// cytoplasm /// endosome membrane /// late endosome membrane nucleus /// nucleus /// endoplasmic reticulum /// membrane /// integral to membrane nucleus /// nucleus /// nucleus /// nucleolus /// mitochondrion /// intracellular membrane-bounded organelle intracellular /// cytosol /// plasma membrane /// postsynaptic density /// cell soma plasma membrane /// integral to plasma membrane /// membrane /// anchored to membrane intracellular /// cytoplasm /// RNA-induced silencing complex intracellular /// nucleus membrane /// integral to membrane nucleus /// DNA-directed RNA polymerase III complex cytoplasm /// Golgi apparatus /// plasma membrane /// membrane /// perinuclear region of cytoplasm cytoplasm /// cytoplasm /// early endosome /// cytosol soluble fraction /// cytoplasm /// cytoplasm plasma membrane /// plasma membrane /// coated pit /// membrane /// cell projection membrane /// melanosome /// intercellular bridge /// clathrin-coated endocytic vesicle intracellular /// plasma membrane /// membrane /// intrinsic to internal side of plasma membrane mitochondrion /// mitochondrial inner membrane /// mitochondrial matrix /// mitochondrial matrix /// mitochondrial matrix nucleus /// nucleus /// cytoplasm intracellular /// nucleus intracellular /// cytoplasm nucleus /// nucleus /// nucleolus /// cytoplasm /// cytoplasm /// centrosome /// PML body /// nuclear speck plasma membrane /// membrane /// integral to membrane nucleus /// nucleoplasm /// nucleolus integral to membrane /// integral to membrane nucleus /// nucleus /// nucleus /// nucleolus /// cytoplasm /// cytoplasm endosome /// endomembrane system /// membrane /// anchored to membrane /// late endosome membrane intracellular /// nucleus /// nucleus /// transcription factor complex /// plasma membrane /// nuclear matrix /// PcG protein complex nucleus /// nuclear pore /// membrane intracellular /// nucleus intracellular /// nucleus nucleus /// cytoplasm /// cytosol /// body /// isoamylase complex phosphoinositide 3-kinase complex condensed chromosome /// nucleus /// nucleus /// nucleus /// cytosol /// DNA-dependent protein kinase-DNA ligase 4 complex /// DNA-dependent protein kinase-DNA ligase 4 complex /// DNA ligase IV complex cytoplasm /// cytoplasm /// cytosol /// cytoskeleton /// receptor complex nucleus /// nucleus /// cytoplasm intracellular /// nucleus pericentriolar material /// cytoplasm /// centrosome /// centrosome /// centriole /// cytoskeleton /// plasma membrane /// cilium /// microtubule /// membrane /// nonmotile primary cilium /// motile secondary cilium /// motile secondary cilium /// centriolar satellite /// BBSome /// cell projection /// cilium membrane /// cilium membrane endoplasmic reticulum /// Golgi apparatus /// membrane /// integral to membrane intracellular /// nucleus nucleus /// nucleus /// nucleus extracellular region /// proteinaceous extracellular matrix /// fibrillar collagen /// extracellular space /// extracellular space /// lysosome /// Golgi apparatus /// intercellular canaliculus cytoplasm /// early endosome /// plasma membrane /// integral to plasma membrane /// membrane /// integral to membrane /// cytoplasmic vesicle /// MHC class I protein complex /// apical part of cell /// apical part of cell /// basal part of cell /// perinuclear region of cytoplasm /// recycling endosome nucleus /// integral to membrane intracellular /// nucleus cytoplasm /// cytoplasm cytoplasm /// microtubule /// microtubule associated complex /// intracellular membrane-bounded organelle nucleus /// nucleus /// spliceosomal complex nucleus /// cytoplasm /// cytoplasm /// cytoskeleton /// plasma membrane /// focal adhesion /// cell cortex /// postsynaptic density /// membrane /// axon /// growth cone /// membrane raft /// perinuclear region of cytoplasm chromatin /// nucleus /// nucleus /// nucleus /// nucleolus /// cytoplasm intracellular /// plasma membrane /// membrane /// membrane nucleus /// nucleolus /// endoplasmic reticulum /// endoplasmic reticulum /// microsome /// cell surface /// membrane /// integral to membrane cytoplasm /// cytoplasm nucleus /// cytoplasm /// plasma membrane /// DNA polymerase III complex /// membrane plasma membrane /// membrane /// integral to membrane mitochondrion condensed chromosome /// condensed chromosome /// nucleus /// nucleus /// chromosome /// nucleolus mitochondrion /// mitochondrial inner membrane /// mitochondrial inner membrane /// membrane /// integral to membrane endoplasmic reticulum /// endoplasmic reticulum /// endoplasmic reticulum membrane /// plasma membrane /// membrane /// integral to membrane /// integral to membrane nucleus /// nucleus /// cytoplasm nucleus /// nucleus nucleus /// nucleus plasma membrane /// membrane /// integral to membrane nucleus /// nuclear speck nucleus /// nucleoplasm /// mitochondrion /// mitochondrion /// mitochondrial inner membrane /// mitochondrial inner membrane /// integral to plasma membrane /// membrane integral to membrane nucleus /// cytoplasm /// voltage-gated potassium channel complex /// membrane nucleus /// nucleus /// nuclear envelope /// cytoplasm /// cytosol /// CD95 death-inducing signaling complex /// perinuclear region of cytoplasm intracellular /// nucleus extracellular region /// proteinaceous extracellular matrix membrane /// integral to membrane intracellular /// cytosol /// ribosome /// ribonucleoprotein complex proteasome complex /// proteasome complex /// nucleus /// nucleus /// nucleolus /// cytoplasm /// cytoplasm /// cytosol endoplasmic reticulum /// membrane /// integral to membrane nucleus /// nucleus /// nucleus /// nucleoplasm cytoplasm /// Golgi apparatus /// trans-Golgi network /// membrane /// extrinsic to membrane nucleoplasm /// cytosol nucleus /// nucleus /// cytoplasm /// cytoplasm nucleus /// nucleus /// PML body nucleus /// spliceosomal complex /// nucleolus intracellular /// cytoplasm /// endoplasmic reticulum intracellular /// plasma membrane /// membrane nucleus /// nucleus endoplasmic reticulum /// endoplasmic reticulum /// endoplasmic reticulum /// membrane /// integral to membrane /// integral to membrane intracellular /// nucleus /// nucleus /// cytoplasm /// cytosol /// ribosome /// cytosolic small ribosomal subunit /// ribonucleoprotein complex plasma membrane /// voltage-gated potassium channel complex /// voltage-gated potassium channel complex /// membrane /// integral to membrane /// sarcolemma /// neuron projection /// cell soma membrane /// integral to membrane cytoplasm /// plasma membrane /// integral to plasma membrane /// membrane /// integral to membrane /// inhibin-betaglycan-ActRII complex nucleus /// nucleus /// plasma membrane membrane fraction /// plasma membrane /// plasma membrane /// postsynaptic density /// membrane /// integral to membrane /// cell junction /// asymmetric synapse /// synaptic cleft /// terminal button /// dendritic spine /// dendritic shaft /// perikaryon /// protein complex /// synapse /// postsynaptic membrane membrane /// integral to membrane nucleus /// integral to membrane membrane /// integral to membrane endoplasmic reticulum /// membrane /// integral to membrane membrane /// integral to membrane /// transport vesicle membrane /// integral to membrane nucleus /// nucleus

Golgi apparatus /// membrane /// integral to membrane intracellular /// nucleus /// nucleus /// cytoplasm /// nuclear body /// nuclear speck intracellular /// membrane fraction /// cytoplasm /// cytosol /// plasma membrane /// membrane /// cytoplasmic membrane-bounded vesicle /// extrinsic to plasma membrane /// lamellipodium /// melanosome membrane /// integral to membrane nuclear ubiquitin ligase complex /// nucleus /// nucleus /// cytoplasm /// cytoplasm /// BRCA1-A complex /// BRISC complex extracellular region /// extracellular region mitochondrion /// mitochondrion /// mitochondrial outer membrane /// peroxisome /// peroxisome /// membrane /// integral to membrane /// integral to mitochondrial outer membrane extracellular region /// extracellular region /// extracellular space /// nucleolus /// Golgi apparatus /// cell surface cytoplasm /// cytosol plasma membrane /// membrane /// anchored to membrane /// cell projection extracellular region /// proteinaceous extracellular matrix /// extracellular matrix soluble fraction /// nucleus /// nucleoplasm /// nucleolus /// nucleolus /// cytoplasm /// cytoplasm /// polysomal ribosome membrane fraction /// mitochondrion /// mitochondrial envelope /// mitochondrial matrix /// plasma membrane cytoplasm /// cytoskeleton /// microtubule /// microtubule associated complex /// microtubule associated complex /// cytoplasmic microtubule membrane fraction /// endoplasmic reticulum /// endoplasmic reticulum membrane /// integral to plasma membrane /// membrane /// integral to membrane

soluble fraction /// nucleus /// nucleus /// nucleoplasm /// cytoplasm /// cytoplasm /// cytoplasm /// spindle /// cytosol /// cytoskeleton /// plasma membrane /// plasma membrane /// plasma membrane /// membrane /// lamellipodium soluble fraction /// nucleus /// nucleus /// cytoplasm /// mitochondrion /// mitochondrion /// mitochondrial intermembrane space /// microsome plasma membrane /// plasma membrane /// cell-cell junction /// cell-cell adherens junction /// membrane /// integral to membrane /// apical junction complex plasma membrane /// plasma membrane /// coated pit /// membrane /// cell projection membrane /// melanosome /// intercellular bridge /// clathrin-coated endocytic vesicle nucleus /// nucleoplasm /// mitochondrion /// mitochondrion /// mitochondrial inner membrane /// mitochondrial inner membrane /// integral to plasma membrane /// membrane cytoplasm /// cytoplasm /// autophagic vacuole /// autophagic vacuole /// pre-autophagosomal structure membrane /// pre-autophagosomal structure membrane /// intracellular membrane-bounded organelle membrane fraction /// membrane fraction /// intermediate filament /// plasma membrane /// plasma membrane /// integral to plasma membrane /// postsynaptic density /// membrane /// integral to membrane /// axon /// dendrite /// axolemma /// asymmetric synapse /// presynaptic membrane /// cell soma /// postsynaptic membrane /// presynaptic active zone

extracellular region /// extracellular region /// proteinaceous extracellular matrix /// collagen type VII /// basement membrane /// basement membrane cytoplasm /// cytoplasm /// autophagic vacuole /// autophagic vacuole /// pre-autophagosomal structure membrane /// pre-autophagosomal structure membrane /// intracellular membrane-bounded organelle mitochondrion /// mitochondrial inner membrane /// peroxisome /// peroxisome /// peroxisomal membrane /// peroxisomal membrane /// integral to peroxisomal membrane /// membrane /// integral to membrane kinetochore /// condensed chromosome kinetochore /// nuclear envelope /// cytoplasm /// centrosome /// spindle /// cytoskeleton /// microtubule /// microtubule associated complex /// axon /// cell leading edge /// neurofilament cytoskeleton

extracellular region /// extracellular region /// proteinaceous extracellular matrix /// collagen type VII /// basement membrane /// basement membrane membrane fraction /// cytoplasm /// endoplasmic reticulum /// Golgi apparatus /// Golgi apparatus /// membrane /// integral to membrane

intracellular /// cytoplasm /// Golgi apparatus /// spindle /// microtubule /// microtubule /// tight junction /// cell junction /// cell soma /// dendritic shaft

extracellular region /// proteinaceous extracellular matrix /// basement membrane /// basal lamina /// endoplasmic reticulum /// laminin-11 complex intracellular /// cytoplasm /// endomembrane system /// endomembrane system /// membrane /// lamellipodium /// growth cone /// filamentous actin /// cell projection /// neuron projection /// cell soma cytoplasm /// Golgi apparatus /// plasma membrane /// plasma membrane /// voltage-gated potassium channel complex /// membrane /// integral to membrane

pericentriolar material /// cytoplasm /// cytoplasm /// centrosome /// centrosome /// cytoskeleton /// membrane /// integral to membrane /// nonmotile primary cilium /// centriolar satellite nuclear envelope /// nuclear envelope /// lysosome /// lysosome /// endosome /// endoplasmic reticulum /// endoplasmic reticulum /// integral to plasma membrane /// integral to plasma membrane /// membrane /// integral to membrane /// integral to membrane /// perinuclear region of cytoplasm /// perinuclear region of cytoplasm

membrane fraction /// lysosome /// lysosome /// lysosomal membrane /// endosome /// late endosome /// late endosome /// plasma membrane /// plasma membrane /// membrane /// integral to membrane /// platelet dense granule membrane /// platelet dense granule membrane extracellular region /// proteinaceous extracellular matrix /// basement membrane /// cytoplasm /// early endosome /// sarcolemma /// melanosome /// protein complex /// perinuclear region of cytoplasm

nucleus /// nucleus /// transcription factor TFIID complex /// transcription factor TFIID complex /// transcription factor TFIID complex /// nucleolus /// cytoplasm /// transcription factor TFTC complex

extracellular region /// plasma membrane /// integral to plasma membrane /// membrane /// integral to membrane /// extrinsic to plasma membrane mitochondrion /// mitochondrion /// mitochondrial inner membrane /// mitochondrial matrix /// mitochondrial matrix /// plasma membrane exocyst /// cytoplasm /// microtubule organizing center /// cytosol /// plasma membrane /// membrane /// extrinsic to membrane /// centriolar satellite

nucleus /// cytoplasm /// endoplasmic reticulum /// endoplasmic reticulum /// microsome /// Golgi apparatus /// membrane /// integral to membrane /// intracellular membrane-bounded organelle exocyst /// cytoplasm /// microtubule organizing center /// cytosol /// plasma membrane /// membrane /// extrinsic to membrane /// centriolar satellite

podosome /// nucleus /// cytoplasm /// cytoplasm /// cytoskeleton /// plasma membrane /// plasma membrane /// actin cytoskeleton /// membrane /// cell projection /// costamere

lysosomal membrane /// microtubule organizing center /// microtubule organizing center /// membrane /// integral to membrane /// integral to membrane /// integral to membrane /// cytoplasmic membrane-bounded vesicle /// cytoplasmic membrane-bounded vesicle /// ATP-binding cassette (ABC) transporter complex soluble fraction /// nucleus /// nuclear envelope /// nuclear envelope lumen /// cytoplasm /// cytosol /// membrane /// nuclear matrix /// nuclear matrix /// extrinsic to membrane /// dendrite /// nuclear membrane /// sarcolemma membrane fraction /// plasma membrane /// plasma membrane /// membrane /// integral to membrane /// apical plasma membrane /// intrinsic to membrane

nuclear inner membrane /// endoplasmic reticulum /// endoplasmic reticulum membrane /// endoplasmic reticulum membrane /// membrane /// integral to membrane /// integral to endoplasmic reticulum membrane plasma membrane enriched fraction /// nucleus /// cytoplasm /// microsome /// plasma membrane /// plasma membrane /// plasma membrane /// membrane /// synaptosome /// extrinsic to membrane /// cell junction /// specific granule /// azurophil granule /// synapse intracellular /// nucleus /// nucleolus /// cytoplasm /// cytosol /// ribosome /// membrane /// integral to membrane /// cytosolic large ribosomal subunit /// ribonucleoprotein complex /// ribonucleoprotein complex

mitochondrion /// mitochondrial outer membrane /// peroxisome /// endoplasmic reticulum /// microsome /// plasma membrane /// membrane /// integral to membrane plasma membrane /// plasma membrane /// coated pit /// membrane /// cell projection membrane /// melanosome /// intercellular bridge /// clathrin-coated endocytic vesicle condensed chromosome /// nucleus /// nucleus /// nucleus /// cytosol /// DNA-dependent protein kinase-DNA ligase 4 complex /// DNA-dependent protein kinase-DNA ligase 4 complex /// DNA ligase IV complex

pericentriolar material /// cytoplasm /// centrosome /// centrosome /// centriole /// cytoskeleton /// plasma membrane /// cilium /// microtubule basal body /// membrane /// nonmotile primary cilium /// motile secondary cilium /// motile secondary cilium /// centriolar satellite /// BBSome /// cell projection /// cilium membrane /// cilium membrane

extracellular region /// proteinaceous extracellular matrix /// fibrillar collagen /// extracellular space /// extracellular space /// lysosome /// Golgi apparatus /// intercellular canaliculus cytoplasm /// early endosome /// plasma membrane /// integral to plasma membrane /// membrane /// integral to membrane /// cytoplasmic vesicle /// MHC class I protein complex /// apical part of cell /// apical part of cell /// basal part of cell /// perinuclear region of cytoplasm /// recycling endosome

nucleus /// cytoplasm /// cytoplasm /// cytoskeleton /// plasma membrane /// focal adhesion /// cell cortex /// postsynaptic density /// membrane /// axon /// growth cone /// membrane raft /// perinuclear region of cytoplasm nucleus /// nucleolus /// endoplasmic reticulum /// endoplasmic reticulum /// microsome /// cell surface /// membrane /// integral to membrane endoplasmic reticulum /// endoplasmic reticulum /// endoplasmic reticulum membrane /// plasma membrane /// membrane /// integral to membrane /// integral to membrane

nucleus /// nucleoplasm /// mitochondrion /// mitochondrion /// mitochondrial inner membrane /// mitochondrial inner membrane /// integral to plasma membrane /// membrane nucleus /// nucleus /// nuclear envelope /// cytoplasm /// cytosol /// CD95 death-inducing signaling complex /// perinuclear region of cytoplasm

endoplasmic reticulum /// endoplasmic reticulum /// endoplasmic reticulum /// membrane /// integral to membrane /// integral to membrane intracellular /// nucleus /// nucleus /// cytoplasm /// cytosol /// ribosome /// cytosolic small ribosomal subunit /// ribonucleoprotein complex plasma membrane /// voltage-gated potassium channel complex /// voltage-gated potassium channel complex /// membrane /// integral to membrane /// sarcolemma /// neuron projection /// cell soma cytoplasm /// plasma membrane /// integral to plasma membrane /// membrane /// integral to membrane /// inhibin-betaglycan-ActRII complex membrane fraction /// plasma membrane /// plasma membrane /// postsynaptic density /// membrane /// integral to membrane /// cell junction /// asymmetric synapse /// synaptic cleft /// terminal button /// dendritic spine /// dendritic shaft /// perikaryon /// protein complex /// synapse /// postsynaptic membrane

intracellular /// membrane fraction /// cytoplasm /// cytosol /// plasma membrane /// membrane /// cytoplasmic membrane-bounded vesicle /// extrinsic to plasma membrane /// lamellipodium /// melanosome

mitochondrion /// mitochondrion /// mitochondrial outer membrane /// peroxisome /// peroxisome /// membrane /// integral to membrane /// integral to mitochondrial outer membrane

membrane fraction /// membrane fraction /// intermediate filament /// plasma membrane /// plasma membrane /// integral to plasma membrane /// postsynaptic density /// membrane /// integral to membrane /// axon /// dendrite /// axolemma /// asymmetric synapse /// presynaptic membrane /// cell soma /// postsynaptic membrane /// presynaptic active zone nuclear envelope /// nuclear envelope /// lysosome /// lysosome /// endosome /// endoplasmic reticulum /// endoplasmic reticulum /// integral to plasma membrane /// integral to plasma membrane /// membrane /// integral to membrane /// integral to membrane /// perinuclear region of cytoplasm /// perinuclear region of cytoplasm

membrane fraction /// lysosome /// lysosome /// lysosomal membrane /// endosome /// late endosome /// late endosome /// plasma membrane /// plasma membrane /// membrane /// integral to membrane /// platelet dense granule membrane /// platelet dense granule membrane lysosomal membrane /// microtubule organizing center /// microtubule organizing center /// membrane /// integral to membrane /// integral to membrane /// integral to membrane /// cytoplasmic membrane-bounded vesicle /// cytoplasmic membrane-bounded vesicle /// ATP-binding cassette (ABC) transporter complex plasma membrane enriched fraction /// nucleus /// cytoplasm /// microsome /// plasma membrane /// plasma membrane /// plasma membrane /// membrane /// synaptosome /// extrinsic to membrane /// cell junction /// specific granule /// azurophil granule /// synapse pericentriolar material /// cytoplasm /// centrosome /// centrosome /// centriole /// cytoskeleton /// plasma membrane /// cilium /// microtubule basal body /// membrane /// nonmotile primary cilium /// motile secondary cilium /// motile secondary cilium /// centriolar satellite /// BBSome /// cell projection /// cilium membrane /// cilium membrane

cytoplasm /// early endosome /// plasma membrane /// integral to plasma membrane /// membrane /// integral to membrane /// cytoplasmic vesicle /// MHC class I protein complex /// apical part of cell /// apical part of cell /// basal part of cell /// perinuclear region of cytoplasm /// recycling endosome membrane fraction /// plasma membrane /// plasma membrane /// postsynaptic density /// membrane /// integral to membrane /// cell junction /// asymmetric synapse /// synaptic cleft /// terminal button /// dendritic spine /// dendritic shaft /// perikaryon /// protein complex /// synapse /// postsynaptic membrane