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Descargar Descargar I-ISSN 2590-7379 (Electrónico) BiomédicaRevista del Instituto Nacional de Salud Volumen 40, No. 4 - Diciembre de 2020, Bogotá, D.C., Colombia, S.A. 1 Portada: Logo de PubMed Central® PubMed Central® es el archivo gratuito en texto completo de los artículos publicados en revistas de literatura biomédica y las ciencias de la vida, seleccionadas para hacer parte de este repositorio, y que se encuentran disponibles en la National Library of Medicine de los U.S. National Institutes of Health. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/ 2 Biomédica Instituto Nacional de Salud VolúmenVolumen 40, Suplemento 40, No. 1 -No. Bogotá, 2 - Bogotá, D.C., ColombiaD.C., Colombia - Marzo - Diciembre de 2020 de 2020 Comité Editorial EDITORES LUIS ALBERTO GÓMEZ CARLOS ARTURO HERNÁNDEZ RUBÉN SANTIAGO NICHOLLS Instituto Nacional de Salud Instituto Nacional de Salud Organización Panamericana de la Salud Bogotá, D.C., Colombia Bogotá, D.C., Colombia Washington, D.C., Estados Unidos EDITORES ASOCIADOS ENRIQUE ARDILA ERIKA SANTAMARÍA Academia Nacional de Medicina Instituto Nacional de Salud Bogotá, D.C., Colombia Bogotá, D.C., Colombia JULIÁN ALFREDO FERNÁNDEZ-NIÑO OMAR SEGURA Universidad del Norte Federación Médica Colombiana Barranquilla, Colombia Bogotá, D.C., Colombia JOSÉ MORENO-MONTOYA ORLANDO TORRES-FERNÁNDEZ Fundación Santa Fe de Bogotá Instituto Nacional de Salud Bogotá, D.C., Colombia Bogotá, D.C., Colombia LEONARD MUNSTERMANN MAGDALENA WIESNER Yale University School of Medicine Instituto Nacional de Salud New Haven, CT, Estados Unidos Bogotá, D.C., Colombia Comité Científico ARNOLDO BARBOSA ANDRÉS DE FRANCISCO JOHN MARIO GONZÁLEZ Universidad del Tolima Organización Mundial de la Salud Universidad de los Andes Ibagué, Colombia Ginebra, Suiza Bogotá, D.C., Colombia ANTONIO BERMÚDEZ FERNANDO DE LA HOZ FELIPE GUHL Instituto Nacional de Salud Universidad Nacional de Colombia Universidad de los Andes Bogotá, D.C., Colombia Bogotá, D.C., Colombia Bogotá, D.C., Colombia JORGE H. BOTERO JOSÉ LUIS DI FABIO ANTONIO IGLESIAS Universidad de Antioquia Organización Panamericana de la Salud Universidad Nacional de Colombia Medellín, Colombia Washington, D.C., Estados Unidos Bogotá, D.C., Colombia ORGE ERNANDO ONADO JORGE JARA GUSTAVO ALONSO CABRERA J H D Universidad de Antioquia Universidad Pontificia Bolivariana Organización Panamericana de la Salud Medellín, Colombia Medellín, Colombia Washington, D.C., Estados Unidos CARLOS ANDRÉS FANDIÑO ERNESTO JARAMILLO VÍCTOR CÁRDENAS Universidad del Valle Organización Mundial de la Salud University of Arkansas Cali, Colombia Ginebra, Suiza Little Rock, AK, Estados Unidos JOSÉ FIGUEROA MARCELO LABRUNA ALBERTO CONCHA-EASTMAN World Health Organization Universidade de São Paulo Guatapé, Colombia Ginebra, Suiza São Paulo, Brasil ZOILO CUÉLLAR LUIS FERNANDO GARCÍA JAIRO LIZARAZO Academia Nacional de Medicina Universidad de Antioquia Hospital Universitario Erasmo Meoz Bogotá, D.C., Colombia Medellín, Colombia Cúcuta, Colombia LUIS GABRIEL CUERVO ALBERTO GÓMEZ JUAN GUILLERMO MCEWEN Organización Panamericana Pontificia Universidad Javeriana Corporación para Investigaciones de la Salud Bogotá, D.C., Colombia Biológicas Washington, D.C., Estados Unidos Medellín, Colombia ENRIQUE GONZÁLEZ PATRICIA DEL PORTILLO University of Texas Health Science Center ROBERTO MENDOZA Corpogén at San Antonio The Hospital for Sick Children Bogotá, D.C., Colombia San Antonio, TX, Estados Unidos Toronto, Ontario, Canada 578 1 RICARDO NEGRONI GUSTAVO C. ROMÁN NANCY GORE SARAVIA Hospital de Infecciosas Methodist Neurological Institute Centro Internacional de Entrenamiento Francisco Javier Muñiz Houston, TX, Estados Unidos e Investigaciones Médicas Buenos Aires, Argentina Cali, Colombia PEDRO ROMERO MARÍA TERESA OCHOA Ludwig Center for Cancer Research ROBERT TESH University of California Los Ángeles University of Lausanne University of Texas Los Ángeles, CA, Estados Unidos Lausana, Suiza GALVESTON, TX, ESTADOS UNIDOS LVARO UIZ JUAN P. OLANO Á R BRUNO TRAVI University of Texas Medical Branch Pontificia Universidad Javeriana University of Texas Galveston, TX, Estados Unidos Bogotá, D.C., Colombia Galveston, TX, Estados Unidos GIOCONDA SAN BLAS BLANCA RESTREPO GUSTAVO VALBUENA Instituto Venezolano de University of Texas University of Texas Investigaciones Científicas Brownsville, TX, Estados Unidos Galveston, TX, Estados Unidos Caracas, Venezuela GERZAÍN RODRÍGUEZ JUAN MIGUEL VILLALOBOS ÁLVARO SANABRIA Universidade Federal de Rondônia Investigador Emérito Hospital Pablo Tobón Uribe Porto Velho, Brasil Instituto Nacional de Salud Medellín, Colombia Universidad de La Sabana Universidad de La Sabana MOISÉS WASSERMAN Bogotá, D.C., Colombia Chía, Colombia Investigador Emérito VÍCTOR E. REYES Instituto Nacional de Salud RICARDO SÁNCHEZ University of Texas Medical Branch Universidad Nacional de Colombia Universidad Nacional de Colombia Galveston, TX, Estados Unidos Bogotá, D.C., Colombia Bogotá, D.C., Colombia CARLOS ARTURO HERNÁNDEZ LINDA GRACE MOLANO MARTHA RENZA ELIZABETH GUZMÁN LUZ ÁNGELA SALGADO Edición y corrección de estilo Asistencia editorial Corrección de estilo Mercadeo digital Diagramación © Instituto Nacional de Salud La revista Biomédica del Instituto Nacional de Salud es una publicación trimestral, eminentemente científica. Está amparada por la resolución número 003768 de 1981, emanada del Ministerio de Gobierno, y con tarifa postal reducida según resolución número 1128 del 5 de mayo de 1982. Ninguna publicación, nacional o extranjera, podrá reproducir ni traducir sus artículos ni sus resúmenes sin previa autorización escrita del editor. Ni la revista, ni el Instituto asumen responsabilidad alguna por los puntos de vista expresados por los autores. 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La revista Biomédica aparece reseñada en Index Medicus/Medline de la National Library of Medicine, en el Science Citation Index Expanded (also known as SciSearch®) y Journal Citation Reports/Science Edition de Thomson Scientific, en SciELO Colombia (Scientific Electronic Library Online), en el índice de la Literatura Latinoamericana en Ciencias de la Salud (LILACS), en la Red de Revistas Científicas de América Latina, el Caribe, España y Portugal (RedAlyC), en el Índice Mexicano de Revistas Biomédicas Latinoamericanas (Imbiomed), en Scopus de Elsevier B.V., en el Sistema de Información Bibliográfica Regional Andina (SIBRA), en CAB Abstracts, Review of Medical and Veterinary Entomology, y forma parte del Índice Nacional de Publicaciones Seriadas Científicas y Tecnológicas Colombianas de Colciencias y del Índice Latinoamericano de Revistas Científicas y Tecnológicas (LATINDEX). INSTITUTO NACIONAL DE SALUD Avenida Calle 26 No. 51-20 Apartado aéreo 80334 y 80080 Bogotá, D.C., Colombia, S.A. URL: http://www.ins.gov.co [email protected] 2 579 Contenido Editorial Biomédica en PubMed Central® Luis Alberto Gómez-Grosso.................................................................................................................................................................................... 582 Imágenes en biomedicina Queratitis herpética atípica con lesiones epiteliales multifocales Virgilio Galvis, Alejandro Tello.................................................................................................................................................................................. 585 Presentación de caso Complicaciones tromboembólicas asociadas con tuberculosis: reporte de un caso pediátrico Natalia Osorio, Martha Mónica Reyes.................................................................................................................................................................... 587 Intoxicación escombroide secundaria al consumo de atún: presentación de un caso María Carolina González, Andrea Carolina Díaz, Jairo Giovanni Moncayo, Jorge Alonso Marín............................................................................ 594 Miasis intestinal humana por Eristalis tenax en un niño de la zona urbana del municipio de Policarpa, Nariño, Colombia Álvaro Francisco Dulce-Villarreal, Angélica María Rojas-Bárcenas, José Danilo Jojoa-Ríos, José Fernando Gómez-Urrego............................... 599 Gemelos de diferentes padres: un caso de superfecundación heteropaternal en Colombia Fernanda Mogollón, Andrea Casas-Vargas, Fredy Rodríguez, William Usaquén.................................................................................................... 604 Hemorragia cerebral fatal después de una mordedura de serpiente Bothrops asper en la región del Catatumbo, Colombia Jairo Lizarazo, Ramón Patiño, Diego Lizarazo, Guadalupe Osorio.......................................................................................................................... 609 Artículo original Los resultados adversos en el tratamiento de la tuberculosis resistente a múltiples fármacos sobrepasan la relación fármaco-microorganismo: resultados de un análisis de correspondencia múltiple Ángela Tobón, Johana Rueda, Diego H. Cáceres, Gloria I. Mejía, Elsa M. Zapata, Fernando Montes, Antonio Ospina, Santiago Fadul, Lizeth Paniagua, Jaime Robledo....................................................................................................................................................................................... 616 Cobertura y
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