Recent Reviews Covers Principally the Early Part of the 2016 Literature

Number 120

compiled by Veronica M. Cornel

Department of Chemistry, Reedley College, 995 Reed Avenue, Reedley, California 93654

Reviews are listed in order of appearance in the sources indicated. In multidisciplinary review journals, only those reviews which fall within the scope of this Journal are included. Sources are listed alphabetically in three categories: regularly issued review journals and series volumes, contributed volumes, and other monographs. Titles are numbered serially, and these numbers are used for reference in the index.

Major English-language sources of critical reviews are covered. Encyclopedic treatises, annual surveys such as Specialist Periodical Reports, and compilations of symposia proceedings are omitted.

This installment of Recent Reviews covers principally the early part of the 2016 literature. Previous installment: J. Org. Chem. 2016, 81(7).

Additional Information Available: A file containing this Recent Review compilation in Microsoft Word and the data in plain text that can be imported into Endnote (using Refer style) and Reference Manager databases.

Regularly Issued Journals and Series Volumes

Accounts of Chemical Research Development and Application of Two-Chamber Reactors and Carbon Monoxide Precursors for Safe Carbonylation 1. Wang, C.; Luo, L.; Yamamoto, H. Metal-Catalyzed Reactions. 2016, 49(4), 594-605. Directed Regio- and Enantioselective Ring-Opening of 11. He, G.; Wang, B.; Nack, W. A.; Chen, G. Syntheses Epoxides. 2016, 49(2), 193-204. and Transformations of α-Amino Acids via Palladium- 2. Bures, J.; Armstrong, A.; Blackmond, D. G. Explaining Catalyzed Auxiliary-Directed sp3 C–H Functionalization. 2016, Anomalies in Enamine Catalysis: "Downstream Species" as a 49(4), 635-45. New Paradigm for Stereocontrol. 2016, 49(2), 214-22. 12. Tejedor, D.; Lopez-Tosco, S.; Mendez-Abt, G.; 3. Sears, J. E.; Boger, D. L. Tandem Intramolecular Diels- Cotos, L.; Garcia-Tellado, F. Propargyl Vinyl Ethers and Alder/1,3-Dipolar Cycloaddition Cascade of 1,3,4-Oxadiazoles: Tertiary Skipped Diynes: Two Pluripotent Molecular Platforms Initial Scope and Applications. 2016, 49(2), 241-51. for Diversity-Oriented Synthesis. 2016, 49(4), 703-13. 4. Depres, J.-P.; Delair, P.; Poisson, J.-F.; Kanazawa, A.; 13. Tantillo, D. J. Speeding Up Sigmatropic Shifts–To Greene, A. E. Diverse Natural Products from Dichloro- Halve or to Hold. 2016, 49(4), 741-9. cyclobutanones: An Evolutionary Tale. 2016, 49(2), 252-61. 14. Lam, Y.-h.; Grayson, M. N.; Holland, M. C.; 5. Dale, E. J.; Vermeulen, N. A.; Juricek, M.; Barnes, J. Simon, A.; Houk, K. N. Theory and Modeling of Asymmetric C.; Young, R. M.; Wasielewski, M. R.; Stoddart, J. F. Catalytic Reactions. 2016, 49(4), 750-62. Supramolecular Explorations: Exhibiting the Extent of Extended 15. Sameera, W. M. C.; Maeda, S.; Morokuma, K. Cationic Cyclophanes. 2016, 49(2), 262-73. Computational Catalysis Using the Artificial Force Induced 6. Roy, S.; Mondal, K. C.; Roesky, H. W. Cyclic Reaction Method. 2016, 49(4), 763-73. Alkyl(amino) Carbene Stabilized Complexes with Low 16. Mayr, H.; Ofial, A. R. Philicities, Fugalities, and Coordinate Metals of Enduring Nature. 2016, 49(3), 357-69. Equilibrium Constants. 2016, 49(5), 952-65. 7. Shi, Y.; Teng, P.; Sang, P.; She, F.; Wei, L.; Cai, J. γ- 17. Halskov, K. S.; Donslund, B. S.; Paz, B. M.; AApeptides: Design, Structure, and Applications. 2016, 49(3), Joergensen, K. A. Computational Approach to Diarylprolinol- 428-41. Silyl Ethers in Aminocatalysis. 2016, 49(5), 974-86. 8. Lash, T. D. Out of the Blue! Azuliporphyrins and 18. Hansen, E.; Rosales, A. R.; Tutkowski, B.; Norrby, Related Carbaporphyrinoid Systems. 2016, 49(3), 471-82. P.-O.; Wiest, O. Prediction of Stereochemistry using Q2MM. 9. Zhou, S.; Li, J.; Schlangen, M.; Schwarz, H. Bond 2016, 49(5), 996-1005. Activation by Metal–Carbene Complexes in the Gas Phase. 19. Sunoj, R. B. Transition State Models for 2016, 49(3), 494-502. Understanding the Origin of Chiral Induction in Asymmetric 10. Friis, S. D.; Lindhardt, A. T.; Skrydstrup, T. The Catalysis. 2016, 49(5), 1019-28. 20. Peng, Q.; Paton, R. S. Catalytic Control in Ubiquitin Chains and Polyubiquitinated Peptides and Proteins. Cyclizations: From Computational Mechanistic Understanding 2016, 16(1), 509-19. to Selectivity Prediction. 2016, 49(5), 1042-51. 21. Wheeler, S. E.; Seguin, T. J.; Guan, Y.; Doney, A. C. Chemical Reviews Noncovalent Interactions in Organocatalysis and the Prospect of Computational Catalyst Design. 2016, 49(5), 1061-9. 39. Mahadevi, A. S.; Sastry, G. N. Cooperativity in 22. Balcells, D.; Clot, E.; Eisenstein, O.; Nova, A.; Noncovalent Interactions. 2016, 116(5), 2775-825. Perrin, L. Deciphering Selectivity in Organic Reactions: A 40. Candeias, N. R.; Paterna, R.; Gois, P. M. P. Multifaceted Problem. 2016, 49(5), 1070-8. Homologation Reaction of Ketones with Diazo Compounds. 2016, 116(5), 2937-81. Advanced Synthesis and Catalysis 41. Tiwari, V. K.; Mishra, B. B.; Mishra, K. B.; Mishra, N.; Singh, A. S.; Chen, X. Cu-Catalyzed Click Reaction in 23. Liu, J.; Chen, G.; Tan, Z. Copper-Catalyzed or - Carbohydrate Chemistry. 2016, 116(5), 3086-240. Mediated C–H Bond Functionalizations Assisted by Bidentate 42. De Risi, C.; Pollini, G. P.; Zanirato, V. Recent Directing Groups. 2016, 358(8), 1174-94. Developments in General Methodologies for the Synthesis of α- 24. Day, D. P.; Chan, P. W. H.; Gold-Catalyzed Ketoamides. 2016, 116(5), 3241-305. Cycloisomerizations of 1,n-Diyne Carbonates and Esters. 2016, 43. Yoshimura, A.; Zhdankin, V. V. Advances in 358(9), 1368-84. Synthetic Applications of Hypervalent Iodine Compounds. 25. Huple, D. B.; Ghorpade, S.; Liu, R.-S. Recent 2016, 116(5), 3328-435. Advances in Gold-Catalyzed N- and O-Functionalizations of 44. De Bruycker, K.; Billiet, S.; Houck, H. A.; Alkynes with Nitrones, Nitroso, Nitro and Nitroxy Species. Chattopadhyay, S.; Winne, J. M.; Du Prez, F. E. Triazoline- diones as Highly Enabling Synthetic Tools. 2016, 116(6), 3919- Angewandte Chemie, International Edition in English 74. 45. Hong, L.; Sun, W.; Yang, D.; Li, G.; Wang, R. 26. Wrackmeyer, B. A Cyclotriborane Dianion and the Additive Effects on Asymmetric Catalysis. 2016, 116(6), 4006- Triboron Cation: "Light Ends" of the Hueckel Rule. 2016, 55(6), 123. 1962-4. 46. Mailyan, A. K.; Eickhoff, J. A.; Minakova, A. S.; 27. Coombs, J. R.; Morken, J. P. Catalytic Enantio- Gu, Z.; Lu, P.; Zakarian, A. Cutting-Edge and Time-Honored selective Functionalization of Unactivated Terminal Alkenes. Strategies for Stereoselective Construction of C–N Bonds in 2016, 55(8), 2636-49. Total Synthesis. 2016, 116(7), 4441-557. 28. Iacobucci, C.; Reale, S.; De Angelis, F. Elusive 47. Goossens, K.; Lava, K.; Bielawski, C. W.; Reaction Intermediates in Solution Explored by ESI-MS: Binnemans, K. Ionic Liquid Crystals: Versatile Materials. 2016, Reverse Periscope for Mechanistic Investigations. 2016, 55(9), 116(8), 4643-807. 2980-93. 48. Becucci, M.; Melandri, S. High-Resolution 29. Barboiu, M.; Stadler, A.-M.; Lehn, J.-M. Controlled Spectroscopic Studies of Complexes Formed by Medium-Size Folding, Motional, and Constitutional Dynamic Processes of Organic Molecules. 2016, 116(9), 5014-37. Polyheterocyclic Molecular Strands. 2016, 55(13), 4130-54. 49. Biedermann, F.; Schneider, H.-J. Experimental 30. Bueschleb, M.; Dorich, S.; Hanessian, S.; Tao, D.; Binding Energies in Supramolecular Complexes. 2016, 116(9), Schenthal, K. B.; Overman, L. E. Synthetic Strategies toward 5216-300. Natural Products Containing Contiguous Stereogenic Quatern- 50. Frey, J. A.; Holzer, C.; Klopper, W.; Leutwyler, S. ary Carbon Atoms. 2016, 55(13), 4156-86. Experimental and Theoretical Determination of Dissociation 31. Chung, W.-j.; Vanderwal, C. D. Stereoselective Energies of Dispersion-Dominated Aromatic Molecular Halogenation in Natural Product Synthesis. 2016, 55(14), 4396- Complexes. 2016, 116(9), 5614-41. 434. 51. Kacprzak, K.; Skiera, I.; Piasecka, M.; Paryzek, Z. 32. Li, Y.; Hari, D. P.; Vita, M. V.; Waser, J. Cyclic Alkaloids and Isoprenoids Modification by Copper(I)-Catalyzed Hypervalent Iodine Reagents for Atom-Transfer Reactions: Huisgen 1,3-Dipolar Cycloaddition (Click Chemistry): Toward Beyond Trifluoromethylation. 2016, 55(14), 4436-54. New Functions and Molecular Architectures. 2016, 116(10), 33. Ghavre, M.; Froese, J.; Pour, M.; Hudlicky, T. 5689-743. Synthesis of Amaryllidaceae Constituents and Unnatural 52. Simeonov, S. P.; Nunes, J. P. M.; Guerra, K.; Derivatives. 2016, 55(19), 5642-91. Kurteva, V. B.; Afonso, C. A. M. Synthesis of Chiral Cyclo- pentenones. 2016, 116(10), 5744-893. The Chemical Record Chemical Society Reviews 34. Singh, A. S.; Sun, S.-S. Structurally Flexible C3- Symmetric Receptors for Molecular Recognition and Their Self- 53. Estager, J.; Holbrey, J. D.; Swadzba-Kwasny, M. Assembly Properties. 2015, 15(6), 1021-44. Halometallate Ionic Liquids - Revisited. 2014, 43(3), 847-86. 35. Kawase, T.; Nishida, J.-i. π-Extended Pentalenes: 54. Iyoda, M.; Shimizu, H. Multifunctional π-Expanded The Revival of the Old Compound from New Standpoints. 2015, Oligothiophene Macrocycles. 2015, 44(18), 6411-24. 15(6), 1045-59. 55. Li, S.; Ma, J.-A. Core-Structure-Inspired Asym- 36. Kuck, D. From Fragmentation to Construction – metric Addition Reactions: Enantioselective Synthesis of From Void to Massive: Fascination with Organic Mass Dihydrobenzoxazinone- and Dihydroquinazolinone-Based Anti- Spectrometry and the Synthesis of Novel Three-Dimensional HIV Agents. 2015, 44(21), 7439-48. Polycyclic Aromatic Hydrocarbons. 2015, 15(6), 1075-109. 56. Butt, N. A.; Zhang, W. Transition Metal-Catalyzed 37. Komarova, B. S.; Tsvetkov, Y. E.; Nifantiev, N. E. Allylic Substitution Reactions with Unactivated Allylic Sub- Design of α-Selective Glycopyranosyl Donors Relying on strates. 2015, 44(22), 7929-67. Remote Anchimeric Assistance. 2016, 16(1), 488-506. 57. Vanjari, R.; Singh, K. N. Utilization of Methyl- 38. Meledin, R.; Mali, S. M.; Brik, A. Pushing the arenes as Versatile Building Blocks in Organic Synthesis. 2015, Boundaries of Chemical Protein Synthesis: The Case of 44(22), 8062-96. 58. Cruz-Cabeza, A. J.; Reutzel-Edens, S. M.; Bernstein, Synthesis of Chiral Tertiary Alcohols by CuI-Catalyzed J. Facts and Fictions About Polymorphism. 2015, 44(23), 8619- Enantioselective Addition of Organomagnesium Reagents to 35. Ketones. 2016, 22(11), 3558-70. 59. Bayne, J. M.; Stephan, D. W. Phosphorus Lewis 81. Pfaffenbach, M.; Gaich, T. The Diaza[5.5.6.6]- Acids: Emerging Reactivity and Applications in Catalysis. 2016, fenestrane Skeleton-Synthesis of Leuconoxine Alkaloids. 2016, 45(4), 765-74. 22(11), 3600-10. 60. Melen, R. L. Dehydrocoupling Routes to Element– 82. Meninno, S.; Lattanzi, A. Organocatalytic Element Bonds Catalysed by Main Group Compounds. 2016, Asymmetric Reactions of Epoxides: Recent Progress. 2016, 45(4), 775-88. 22(11), 3632-42. 61. Milnes, K. K.; Pavelka, L. C.; Baines, K. M. 83. Sazonov, P. K.; Beletskaya, I. P. Carbonyl- Cycloaddition of Carbonyl Compounds and Alkynes to metallates–A Special Family of Nucleophiles in Aromatic and (Di)Silenes and (Di)Germenes: Reactivity and Mechanism. Vinylic Substitution Reactions. 2016, 22(11), 3644-53. 2016, 45(4), 1019-35. 84. Fascione, M. A.; Brabham, R.; Turnbull, W. B. 62. Chandra Mondal, K.; Roy, S.; Roesky, H. W. Silicon Mechanistic Investigations into the Application of Sulfoxides Based Radicals, Radical Ions, Diradicals and Diradicaloids in Carbohydrate Synthesis. 2016, 22(12), 3916-28. 2016, 45(4), 1080-111. 85. Bunz, U. H. F.; Engelhart, J. U. The Palladium Way 63. Stennett, T. E.; Harder, S. s-Block Amidoboranes: to N-Heteroacenes. 2016, 22(14), 4680-9. Syntheses, Structures, Reactivity and Applications. 2016, 45(4), 86. Gabriele, B.; Mancuso, R.; Veltri, L. Recent 1112-28. Advances in the Synthesis of Indanes and Indenes. 2016, 64. Wang, Q.; Su, Y.; Li, L.; Huang, H. Transition-Metal 22(15), 5056-94. Catalysed C–N Bond Activation. 2016, 45(5), 1257-72. 87. Teng, P.; Shi, Y.; Sang, P.; Cai, J. γ-AApeptides as 65. Borie, C.; Ackermann, L.; Nechab, M. Enantiosel- a New Class of Peptidomimetics. 2016, 22(16), 5458-66. ective Syntheses of Indanes: From Organocatalysis to C–H 88. Ito, M.; Tahara, Y.-k.; Shibata, T. Strategies for the Functionalization. 2016, 45(5), 1368-86. Total Synthesis of Clavicipitic Acid. 2016, 22(16), 5468-77. 66. Rickhaus, M.; Mayor, M.; Juricek, M. Strain- 89. Mankad, N. P. Selectivity Effects in Bi-metallic Induced Helical Chirality in Polyaromatic Systems. 2016, 45(6), Catalysis. 2016, 22(17), 5822-9. 1542-56. 90. Campos, J.; Lopez-Serrano, J.; Peloso, R.; 67. Ardkhean, R.; Caputo, D. F. J.; Morrow, S. M.; Shi, Carmona, E. Methyl Complexes of the Transition Metals. H.; Xiong, Y.; Anderson, E. A. Cascade Polycyclizations in 2016, 22(19), 6432-57. Natural Product Synthesis. 2016, 45(6), 1557-69. 91. Dominguez, G.; Perez-Castells, J. Alkenes in 68. Wu, W.-T.; Zhang, L.; You, S.-L. Catalytic Asym- [2+2+2] Cycloadditions. 2016, 22(20), 6720-39. metric Dearomatization (CADA) Reactions of Phenol and Aniline Derivatives. 2016, 45(6), 1570-80. Chemistry of Heterocyclic Compounds 69. Li, W.; Zhang, J. Recent Developments in the Synthesis and Utilization of Chiral β-Aminophosphine 92. Kim, D. G.; Vershinina, E. A. Synthesis and Derivatives as Catalysts or Ligands. 2016, 45(6), 1657-77. Properties of Thiazolo- and Oxazolo[3,2-a]Quinolinium 70. Galan, A.; Ballester, P. Stabilization of Reactive Systems and Their Hydrogenated Derivatives. 2014, 50(7), Species by Supramolecular Encapsulation. 2016, 45(6), 1720- 911-31. 37. 93. Sultanova, R. M.; Khanova, M. D.; Zlotskii, S. S. 71. Lledo, A.; Pla-Quintana, A.; Roglans, A. Allenes, The Insertion Reaction Of Diazocarbonyl Compounds at C-H Versatile Unsaturated Motifs in Transition-Metal-Catalysed Bonds in the Synthesis of Biologically Active Nitrogen- and [2+2+2] Cycloaddition Reactions. 2016, 45(8), 2010-23. Oxygen-Containing Heterocycles. 2015, 51(9), 775-84. 72. Chen, J.-R.; Hu, X.-Q.; Lu, L.-Q.; Xiao, W.-J. 94. Deeb, A.; Abdelgawad, A. A. M. Utility of 3- Visible Light Photoredox-Controlled Reactions of N-Radicals Amino-1H-Pyrazolo[3,4-C]Pyridazine in Heterocyclic Syn- and Radical Ions. 2016, 45(8), 2044-56. thesis. 2015, 51(9), 785-98. 73. Trost, B. M.; Masters, J. T. Transition Metal- 95. Urbanaite, A.; Cikotiene, I. Synthesis of 4H- Catalyzed Couplings of Alkynes to 1,3-Enynes: Modern Thiazines. 2016, 52(1), 1-3. Methods and Synthetic Applications. 2016, 45(8), 2212-38. 96. Bakulev, V. A.; Beryozkina, T. A. NH-1,2,3- 74. Andres, P.; Ballano, G.; Calaza, M. I.; Cativiela, C. Triazoles: Synthesis and Reactions with Electrophilic Agents. Synthesis of α-Aminoboronic Acids. 2016, 45(8), 2291-307. 2016, 52(1), 4-6. 75. Levi, L.; Mueller, T. J. J. Multicomponent Synth- 97. Mierina, I.; Jure, M. Alkylidene and Arylidene eses of Functional Chromophores. 2016, 45(10), 2825-46. Meldrum's Acids as Versatile Reagents for the Synthesis of 76. Gensch, T.; Hopkinson, M. N.; Glorius, F.; Wencel- Heterocycles. 2016, 52(1), 7-9. Delord, J. Mild Metal-Catalyzed C–H Activation: Examples and 98. Mierina, I.; Jure, M. Nitroolefins as Starting Concepts. 2016, 45(10), 2900-36. Materials for 5-Membered N-Heterocycles. 2016, 52(1), 10-2. 99. Chalikidi, P. N. O,S-Disubstituted Xantho- Chemistry - A European Journal genates in Heterocyclic Synthesis. 2016, 52(1), 13-4. 100. Kornev, M. Y.; Sosnovskikh, V. Y. Synthesis and 77. Froimowicz, P.; Zhang, K.; Ishida, H. Intra- Chemical Properties of Chromone-3-Carboxylic Acid. 2016, molecular Hydrogen Bonding in Benzoxazines: When Structural 52(2), 71-83. Design Becomes Functional. 2016, 22(8), 2691-707. 101. Petuskovs, A.; Shubin, K. Synthesis of 1,3- 78. James, M. J.; O'Brien, P.; Taylor, R. J. K.; Unsworth, Dihydro-2H-benzo[d]azepin-2-ones. 2016, 52(2), 84-6. W. P. Synthesis of Spirocyclic Indolenines. 2016, 22(9), 2856- 102. Gutnov, A. Furan Ring as a Surrogate for Carboxy 81. Group. 2016, 52(2), 87-9. 79. Zeng, Y.; Ni, C.; Hu, J. Recent Advances in the 103. Bogdanov, A. V.; Mironov, V. F. Synthesis of One-Step Synthesis of Distally Fluorinated Ketones. 2016, Isatoic Anhydride Derivatives. 2016, 52(2), 90-2. 22(10), 3210-23. 104. Roopan, S. M.; Palaniraja, J. Synthesis of 80. Rong, J.; Pellegrini, T.; Harutyunyan, S. R. Indazoloquinazoline System. 2016, 52(2), 93-5. 105. Saeed, A.; Qamar, R. Recent Trends in the 126. Xu, X.-H.; Qing, F.-L. Recent Developments in the Synthesis of 1,3-Oxazines. 2016, 52(2), 96-8. Fluorofunctionalization of Alkenes. 2015, 19(16), 1566-78. 127. Inoue, M.; Shiosaki, M. Fluorination and Coordination Chemistry Reviews Fluoroalkylation of Organolithium, Magnesium, and Zinc Reagents. 2015, 19(16), 1579-91. 106. Prochowicz, D.; Kornowicz, A.; Justyniak, I.; 128. Shibatomi, K. Catalytic Enantioselective Lewinski, J. Metal Complexes Based on Native Cyclo- Constructions of Trifluoromethylated Chiral Stereogenic dextrins: Synthesis and Structural Diversity. 2016, 306(Part_1), Centers via the Conjugate Addition to CF3-Alkenes: Overview 331-45. of Current Progress. 2015, 19(16), 1619-37. 107. Coudert, F.-X.; Fuchs, A. H. Computational 129. Lu, Y.; Liu, C.; Chen, Q.-Y. Recent Advances in Characterization and Prediction of Metal–Organic Framework Difluoromethylation Reaction. 2015, 19(16), 1638-50. Properties. 2016, 307(Part_2), 211-36. 130. Shi, Y.; Jiang, W.; Auckloo, B. N.; Wu, B. Several 108. Loxq, P.; Manoury, E.; Poli, R.; Deydier, E.; Classes of Natural Products with Metal ion Chelating Ability. Labande, A. Synthesis of Axially Chiral Biaryl Compounds by 2015, 19(19), 1935-53. Asymmetric Catalytic Reactions with Transition Metals. 2016, 131. Malinak, D.; Gonda, J.; Korabecny, J.; Dolezal, R.; 308(Part_2), 131-90. Honegr, J.; Soukup, O.; Buzga, M.; Kuca, K. A Review of the 109. Das, P.; Linert, W. Schiff Base-Derived Total Synthesis of (+)-Lactacystin and its Analogs. 2015, Homogeneous and Heterogeneous Palladium Catalysts for the 19(20), 1980-2001. Suzuki–Miyaura Reaction. 2016, 311, 1-23. 132. Kumbhar, A.; Salunkhe, R. Recent Advances in 110. Khan, A.; Foucher, D. Hypercoordinate Com- Biopolymer Supported Palladium in Organic Synthesis. 2015, pounds of the Group 14 Elements Containing κn-C,N-, C,O-, 19(21), 2075-121. C,S- and C,P-ligands. 2016, 312, 41-66. 133. Heravi, M. M.; Asadi, S.; Nazari, N.; Lashkariani, 111. Bolotin, D. S.; Bokach, N. A.; Kukushkin, V. Y. B. M. Developments of Corey-Fuchs Reaction in Organic and Coordination Chemistry and Metal-Involving Reactions of Total Synthesis of Natural Products. 2015, 19(22), 2196-219. Amidoximes: Relevance to the Chemistry of Oximes and 134. Gangemi, C. M. A.; Pappalardo, A.; Sfrazzetto, G. Oxime Ligands. 2016, 313, 62-93. T. Assembling of Supramolecular Capsules with 112. Cui, P.; Chen, Y. Boratabenzene Rare-Earth Metal Resorcin[4]arene and Calix[n]arene Building Blocks. 2015, Complexes. 2016, 314, 2-13. 19(23), 2281-308. 113. Zhao, D.; Xie, Z. Recent Advances in the 135. Oueslati, I. Calixazacrowns from Molecular Chemistry of Carborynes. 2016, 314, 14-33. Receptors to Advanced Responsive Materials. 2015, 19(23), 114. Pop, L.-C.; Saito, M. Serendipitous Reactions 2309-20. Involving a Silicone Grease. 2016, 314, 64-70. 136. Heravi, M. M.; Nazari, N. Bischler–Napieralski 115. Horacek, M. Titanocene Sulfide Chemistry. 2016, Reaction in Total Synthesis of Isoquinoline-Based Natural 314, 83-102. Products. An Old Reaction, a New Application. 2015, 19(24), 116. Bhattacharjee, H.; Muller, J. Metallocenophanes 2358-408. Bridged by Group 13 Elements. 2016, 314, 114-33. 137. Che, J.; Xing, D.; Hu, W. Metal-Catalyzed Cross- 117. Hirano, M.; Komiya, S. Oxidative Coupling Coupling of Terminal Alkynes with Different Carbene Reactions at Ruthenium(0) and Their Applications to Catalytic Precursors. 2016, 20(1), 41-60. Homo- and Cross-Dimerizations. 2016, 314, 182-200. 138. Ma, X.; Cooper, S. M.; Yang, F.; Hu, W.; Sintim, H. O. Alkaloid Synthesis via Carbenoid Intermediates. 2016, Current Organic Chemistry 20(1), 82-101. 139. Ma, J.; Zhang, L.; Zhu, S. Enynal/Enynone: A Safe 118. Bhowmik, S.; Batra, S. Applications of Morita– and Practical Carbenoid Precursor. 2016, 20(1), 102-18. Baylis–Hillman Reaction to the Synthesis of Natural Products 140. Potapov, V. A.; Musalov, M. V.; Musalova, M. V.; and Drug Molecules. 2014, 18(24), 3078-119. Amosova, S. V. Recent Advances in Organochalcogen Synthesis 119. Wani, M. Y.; Balakrishna, A.; Kumar, S.; Sobral, Based on Reactions of Chalcogen Halides with Alkynes and A. J. F. N. Covalently Linked Free-Base and Metallo-Bis- Alkenes. 2016, 20(2), 136-45. Porphyrins: Chemistry and Diversity. 2015, 19(7), 599-651. 141. Liu, X.; Zhang, H.; Chang, F.; Huang, S.; Yang, K.; 120. Bai, Y.; Dai, M. Strategies and Methods for the Yang, S. Catalytic Transformations of Organic Compounds and Synthesis of Anticancer Natural Product Neopeltolide and its Biomass Derivatives with Functionalized Metal-Organic Analogs. 2015, 19(10), 871-85. Frameworks. 2016, 20(7), 761-76. 121. Wang, Z.; Gao, H.-L.; Chen, X.-D. Some Recent 142. Bugarcic, Z. M.; Kostic, M. D.; Divac, V. M. Synthetic Development on Compounds with Potent Activities Stereo- and Regioselective Synthesis of Cyclic Ethers by Means on Hormone-sensitive Breast Cancers. 2015, 19(10), 898-918. of Organoselenium- Mediated Cyclization of Unsaturated 122. Rossi, R.; Bellina, F.; Lessi, M.; Manzini, C.; Alcohols. 2016, 20(7), 777-97. Marianetti, G.; Perego, L. A. Recent Applications of 143. Zambare, A. S.; Kalam Khan, F. A.; Zambare, S. P.; Phosphane-Based Palladium Catalysts in Suzuki–Miyaura Shinde, S. D.; Sangshetti, J. N. Recent Advances in the Reactions Involved in Total Syntheses of Natural Products. Synthesis of Coumarin Derivatives via Pechmann Con- 2015, 19(14), 1302-409. densation. 2016, 20(7), 798-828. 123. Jayathilaka, L.; Gupta, S.; Huang, J.-S.; Lee, J.; 144. Tilvi, S.; Singh, K. S. Synthesis of Oxazole, Lee, B.-S. Synthesis of Diastereomers of Alliin, Seleno-alliin, Oxazoline and Isoxazoline Derived Marine Natural Products: A and Isoalliin. 2015, 19(14), 1428-35. Review. 2016, 20(8), 898-929. 124. Heravi, M. M.; Fard, M. V.; Faghihi, Z. Recent 145. Borys, K. M.; Ochal, Z. Synthetic Approaches to Applications of Birch Reduction in Total Synthesis of Natural Aryl Halomethyl Sulfones. 2016, 20(9), 963-70. Products. 2015, 19(15), 1491-525. 146. Li, D.; Wang, K.-W. Natural New Sesquiterpenes: 125. Han, J.-B.; Hao, J.-H.; Zhang, C.-P.; Qin, H.-L. Structural Diversity and Bioactivity. 2016, 20(9), 994-1042. Recent Progress in Metal-Mediated Trifluoroethylation. 2015, 147. Heravi, M. M.; Zadsirjan, V.; Dehghani, M. 19(16), 1554-65. Reactivity of Benzo[b]furans: A Full Perspective. 2016, 20(10), 1069-134. 167. Wang, L.; Liu, J. Synthetic Applications of 148. Cao, M.; Hao, Y.; Xu, Z.; Liu, S. H.; Yin, J. 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Index

Acetylphenothiazines, 231 coupling, with Pd and amino bidendate Cu, 23 Alcohols, dehydration substitution, 261 acids, 232 oxidation, 208 tertiary, chiral, 80 olefination, 260 with Pd and amino acids, 232 Aldol reaction, bioactive compounds, Aryl halomethyl sulfones, 145 with Rh, 163 153 Arylation, transition-metal-free, 223 Chalcones, Michael addition, 226 Alkaloids, 1,3-dipolar cycloaddition, 51 with transition metals, 246 Chloropyrazolecarboxaldehydes, 225 α-tertiary amine, 207 Arylidenes, heterocycle synthesis, 97 Chromones, ring opening/closure, 182 clavicipitic acid, 88 Arylmethylene Chromophores, multicomponent synthesis, click chemistry, 51 bismethylphenylpyrazolol, 192 75 leuconoxine, 81 Asymmetric catalysis, additive effect, Click chemistry, 44, 51 Morita–Baylis–Hillman 45 carbohydrates, 41 synthesis, 118 computational chemistry, 14 C–N bond activation, 64 synthesis, via metal carbenoids, non-covalent interactions, 254 C–N bond formation, stereoselective, 138 transition state, 19 46 Alkene–nitrile interconversion, 234 Atropisomerism, 108 C–N cross coupling, Cu, 233 Alkenes, cycloaddition, 91 Aza-fluorocyclization, 184 Computational chemistry, 18 terminal, enantioselective Azlactones, synthesis, 156 aminocatalysis, 17 functionalization, 27 Azuliporphyrins, 8 artificial force induction, 15 Alkyl amino carbenes, cyclic, 6 Benzazepinones, 101 catalyst design, 20-1 Alkylidenes, heterocycle synthesis, 97 Benzhydrylium ion, 16 chiral induction, 19 Alkynes, cyclotrimerization, 249 Benziodoxolones, trifluoromethylation, 32 selectivity, 22 N- and O-difunctionalizations, 25 Benzodioxane lignan, 202 Continuous flow synthesis, 155 terminal, cross coupling, 137 Benzofurans, 147 Corey Fuchs olefination, 133 terminal, with carbenes, 137 Benzoxazines, H-bonding, 77 Corticosteroids, fluorinated, 185 with pyridine oxide, 242 Biaryls, chiral, 108 Coumarins, heterocycles, 203 Allenes, in cycloadditions, 71 Bimetallic catalysis, chemoselectivity, via Pechmann condensation, Alliin, synthesis, 123 89 143 Allylic substitution, 56 regioselectivity, 89 Cumyl keto ester coupling, 256 Amaryllidaceae alkaloids, 33 stereoselectivity, 89 Cyclization, computational catalyst Amidines, arylation, 150 Birch reduction, 124 design, 20 Amidoboranes, 63 Boratabenzenes, 112 Cycloaddition, dipolar, 265 Amidoximes, coordination chemistry, Bronsted acid catalyst, chiral carbon, Cyclodextrin metal complexes, 106 111 236 Cyclopentenones, chiral, 52 Amination, memory of chirality, 241 Butenolides, 156 Cyclophanes, cationic, 5 Amines, cyanoacetylation, 224 synthesis, 220 Cyclotriborane, aromaticity, 26 using xanthates, 247 Calixarene supramolecules, 134 Decalins, multifunctional, 198 Amino acids, biooconjugates, 248 Calixazacrowns, 135 Dehydrocoupling, 60 synthesis, 11 Carbaporphyrinoids, 8 Diarylprolinol silyl ethers, 17 Aminoboronic acid, 74 Carbene transfer, Au, 271 Diazirines, photoaffinity labeling, 174 Aminocatalysis, 17, 262 Carbenoids, from enynones, 139 Diazocarbonyls, N,O-heterocycle cycloaddition, 253 Carbohydrates, septanose, 166 synthesis, 93 Aminoimidazoles, 191 synthesis, with sulfoxides, 84 Dichlorocyclobutanone, natural product Aminophosphines, 69 thiyl-radical reactions, 170 synthesis, 4 Aminopyrazolopyridazines, heterocycle Carbonylation, two chamber reactors, Diels–Alder reaction, silylated acid synthesis, 94 10 catalyst, 235 Amyloid peptides, solid phase Carbonylmetallates, 83 Difluoromethylation, 129 synthesis, 7 Carborynes, 113 Difluoropropene, monofluoroalkene Anilines, dearomatization, 68 Carboxylic acids, chromones, 100 synthesis, 250 using xanthates, 247 Carotenoids, photooxygenation, 216 Dihydrobenzoxazinones, 55 Anti HIV agents, 55 Cascade pericyclization, 67 Dihydronaphthalenes, azaarylation, 157 Anticancer agents, neopeltolide, 120 Cascade polycyclization, 67 oxyarylation , 157 tetrahydropyran, 120 Cascade reactions, diynes, 12 Dihydropyranones, synthesis, 152 Antipyrine heterocycles, 193 propargyl ethers, 12 Dihydroquinazolinones, 55 Antitumor agents, 121 Cation-pi interactions, 39 Diketopiperazine, lactim ether, 180 marine macrolides, 179 Cavitands, 70 Diphenyltriazines, 189 triterpenoids, 201 C–C bond formation, Fe complex, 204 Diterpenes, glycosylated, 199 Aromatics, bromination, 257 C–H bond activation, 76 Diterpenoids, aromatic abietane, 197 Diversity oriented synthesis, 12, 155 Insecticides, sesquiterpenes, 151 Oxazines, 105 Diyne carbonates, cycloisomerization, Au, Ionic liquids, 211 Oxazoles, marine natural product, 144 24 crystals, 47 Oxazoloquinolinium, 92 Diynes, tertiary, skipped, 12 halometallate, 53 Oxidative coupling, Ru, 117 Electrospray mass spectrometry, 28 Isatoic anhydrides, 103 Oxocarbenium aldol reaction, Enamine catalysis, 2 Isoalliin, synthesis, 123 enantioselective, 236 Enynes, alkyne coupling, 73 Isocarbostyril anti-cancer agents, 33 Palladium, biopolymer supported, 132 Epoxides, regioselective ring opening, 1 Isocyanides, 215 Pauson–Khand reaction, 172 with organocatalysts, 82 Isocyanoterpenes, 195 Pentalenes, 35 Ester coupling, 196 Isoflavonoids, synthesis, 157 Peptidomimetics, 7, 87 Ethers, cyclic, with organoselenium, Isoprenoids, 1,3-dipolar cycloaddition, Phenols, dearomatization, 68 142 51 Phosphoric acid heterodimers, 255 Flavanones, chiral, synthesis, 245 Isoquinolines, synthesis, 136 Phosphorus, Lewis acid catalyst, 59 Flavonoids, ion-chelating, 130 Ketoamides, 42 ylides, annulation, 169 Fluorene natural products, 267 Ketones, alkylation/reduction, 258 Photochemistry, copper catalyst, 233 Fluorenone natural products, 267 asymmetric addition, 55 Photoredox catalysis, hypervalent Fluoride ions, 269 cyclohexyl, synthesis, 244 iodine(III), 167 Fluorinated steroids, 185 fluorinated, 79 N radicals, 72 Fluorination, alkenes, 126 with diazo compounds, 40 Phytochelatins, ion-chelating, 130 benzylic compounds, 161 with organomagnesium Pillararenes, synthesis, 148 organometallic reagents, 127 nucleophiles, 80 Pipecolic acid, 221 Fluoroalkylation, organometallic Kinetics, 16 Polycyclic aromatic hydrocarbons, 36 reagent, 127 Lactacystins, synthesis, 131 Polymorphism, 58 Fluoroalkylindoles, 186 Lactams, β macrocyclic, 177 Porphyrins, metallo-, 119 Furan ring, 102 Lewis acids, green, 228 Propargyl vinyl ethers, 12 Furanones, synthesis, 178 ZrCl4, 228 Protein synthesis, 38 Furans, synthesis, 178 ZrOCl2, 228 Pseudopterosin aglycon, 199 Glyceraldehydes, chiral synthon, 213 Ligand strands, polyheterocyclic, 29 Pyrazole carboxylates, 190 Glycoconjugates, from thiyl-radicals, Marine macrolide aplyronine, 179 Pyridazinoquinoxaline, 175 170 Marine natural product, 206 Pyridine, lithiation, 176 Gold, catalyst, 24 Marine terpenoids, cyanide, 195 Pyrroloindazoles, 181 domino reactions, 272 Meldrum acids, heterocycle synthesis, Pyrroloindoles, 194 homogeneous catalysis, 270, 97 Quinolones, 175 272 Metal organic framework catalysts, 141 Radical cyclization, Cu, 171 nitrones, 25 Metal–carbene complexes, gas phase Resorcinarene supramolecules, 134 Guanidine arylation, 150 activation, 9 Ruthenium rhodium catalyst, C-C Halo-alkylthiophenes, 212 Metallocenium chemistry, 252 cleavage, 162 Halogenation, stereoselective, 31 Metallocenophanes, bridged by group Selenoalliin, synthesis, 123 Helicenes, chirality, 66 13, 116 Sesquiterpenes, bisabolane, 151 Heteroacenes, 85 Methane, borylation, 237-8 curcumene, 151 Heteroaromatic complexes, dissociation Methoxybenzyl esters, 214 lactones, oligomeric, 209 energy, 50 Methyl complexes, 90 Sesquiterpenoids, bioactivity, 146 Heteroarylation, 268 Methylarenes, 57 Siderophores, ion-chelating, 130 Heterocycles, 5-membered, with Michael acceptor, fluorinated, 183 Sigmatropic rearrangements, 13 microwaves, 187 Molecular clusters, 39 Silicon radicals, 62 6-membered, cascade reaction, Molecular recognition, 34 Silicone cages, 114 229 Molybdenum reagent, 168 Silylarylboronate, 251 antipyrine, 193 Mukaiyama-Mannich reaction, Silylheteroarylboronate, 251 circulenes, 243 enantioselective, 236 Spectroscopy, high resolution, fluorinated, 184 Mustard carbonates, 218 molecular complexes, 48 from indanediones, 159 Naphthalenedicarbonitrile, 188 Stereocenters, quaternary, carbon, 30, ketene aminal reaction, 230 Natural products, ion chelating, 130 205 Heterogeneous catalysts, metal/organic, Neopeltolide, synthesis, 120 Stereochemistry, computational 217 N-Heterocyclic carbenes, 240 prediction, 18 Hydrofurans, synthesis, 178 Niobium catalyst, 154 Stereoselectivity, computational Hydrogenation, supported Pd, 132 Nitrones, addition to alkynes, 25 chemistry, 22 Hydrosilylation, dinickel catalysts, 249 Nitroolefins, N-heterocycles, 98 Sulfines, 165 Hydroxynaphthoquinones, 149 Nitroso aldol reaction, 259 Supramolecules, 39 Hypervalent iodine 32, 43 Nucleophiles, 16 binding energy, 49 Imidazopyridines, 227 Oligosaccharides, 37 cyclophanes, 5 Indanes, 65 Oligothiophenes, 54 encapsulation, 70 sythesis, 86 Organoboron, allylic substitution, 263 Suzuki–Miyaura reaction, Indazoloquinazolines, 104 Organocatalysis, 21 intermediates, Indenes, synthesis, 86 Organochalcogens, synthesis, 140 239 Indolenine, spirocyclic, 78 Organogermenes, 61 phosphane–Pd, 122 Indoles, dearomatization, 219 Organomagnesium, 264 Pd catalyst, 109 fluoroalkyl, 186 Organometallic metal frameworks, 107 Target oriented Indolines, via interrupted Fischer Organotin, hypercoordinates, 110 synthesis , 155 indolization, 222 Organozinc, 264 Terpenoids, Morita–Baylis–Hillman Indoloquinolines, biogenesis, 158 Oxadiazoles, cycloaddition, 3 synthesis, 118 Insect pheromones, 200 Diels–Alder cascade, 3 Tetracyanoethene, heterocyclization, 188 Tetrahydroquinolines, 210 Tetralones, α-arylation, 157 Thiazines, synthesis, 95 Thiazoloquinolinium, 92 Thiosugars, from thiyl-radicals, 170 Titanium enolates, 164 Titanocene sulfide, 115 Tosylhydrazones, coupling, 173 Triazenes, conjugated, 160 Triazoles, 96 Triazolinediones, 44 Triboracyclopropenyl dianion, 26 Tribromoolefins, terminal alkyne synthesis, 133 Trifluoroethylation, 125 Trifluoromethyl stereogenic centers, 128 Trifluoromethylation, 32 Trifluoromethylphenyldiazirine, 174 Trihaloisocyanuric acid, 155 Triterpenoids, pentacyclic N heterocycle, 201 Ubiquitin protein synthesis, 38 Vitamin A, synthesis, 266 Xanthogenates, O,S-disubstituted, 99