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2019 Joint Meeting Program AAP ASCI APSA JOINT MEETING Meeting APRIL 5 - 7, 2019 FAIRMONT CHICAGO Program MILLENNIUM PARK & Abstracts CHICAGO, ILLINOIS JointMeeting.org #JointMeeting2019 Network: Fairmont_Meeting Code: jointmtg American Physician Scientists Association SPECIAL EVENTS AT THE 2019 AAP/ASCI/APSA JOINT MEETING FRIDAY, APRIL 5 ASCI President’s Reception Honoring Donald Seldin and Holly Smith 6:00 p.m. – 7:00 p.m. Gold Room ASCI Dinner and New Member Induction Ceremony (Ticketed event) 7:30 p.m. – 9:45 p.m. Rouge Room, Lobby Level After-Dinner Speaker: Victor J. Dzau, MD, National Academy of Medicine APSA Welcome Reception (All attendees welcome; Ticketed event; ID required) 9:00 p.m. – Midnight Mid-America Club, Aon Center (Off-site) SATURDAY, APRIL 6 ASCI Food and Science Evening (Ticketed event; ID required) 6:30 p.m. - 9:30 p.m Mid-America Club, Aon Center (Off-site) Featuring Poster Presentations by the ASCI’s 2019 Young Physician-Scientist Award Recipients AAP Banquet and New Member Induction Ceremony (Ticketed event, formal attire required) 7:00 p.m. – 9:30 p.m. Imperial Ballroom, Level B2 Health Equity: Accelerating the Bend toward Justice After Dinner Speaker: Claire Pomeroy, MD, MBA, Albert and Mary Lasker Foundation APSA Dinner (Ticketed event) 7:30 p.m. - 9:00 p.m. Rouge Room, Lobby Level On Virulence Dinner Speaker: Arturo Casadevall, MD PhD, Johns Hopkins University Dessert Reception and Best Poster Awards (Open to all) 9:45 p.m. – 11:30 p.m. Imperial Lobby, Level B2 SUNDAY, APRIL 7 APSA Residency Luncheon 12:30 p.m. - 2:30 p.m. Rouge Room, Lobby Level 2019 AAP/ASCI/APSA Joint Meeting PROGRAM CONTENTS General Program Information 2 Continuing Medical Education Information 3 Joint Program Planning Committee & APSA Events Committee 5 Scientific Program Schedule 6 Speaker Biographies 16 Call for Nominations: 2020 Harrington Prize for Innovation in Medicine 31 2019 AAP/ASCI/APSA Leadership 32 Travel Award Recipients 34 Call for Nominations: George M. Kober Medal 36 Oral Presentations & Poster Abstracts 37 Oral Presentations & Poster Abstracts Author Index 176 Hotel Floor Plans 180 Future Joint Meeting Dates Inside Back Cover Joint Meeting Sponsors Back Cover 1 www.jointmeeting.org GENERAL PROGRAM INFORMATION Registration Desk Hours Poster Session Schedule Friday, April 5 7:00 a.m. – 6:30 p.m. (Location: B2, Imperial Ballroom) Saturday, April 6 7:00 a.m. – 5:00 p.m. Friday, April 5 Sunday, April 7 7:30 a.m. – 10:00 a.m. 1:00pm – 3:00pm Poster Setup 6:15pm – 9:30pm Informal Viewing: Presenters do not need Americans with Disabilities Act to be at posters Event staff will be glad to assist you with any special needs (i.e., physical, dietary, etc.). Please contact the Registration Desk at the Saturday, April 6 meeting if you require any special assistance. TWO Poster Presentation Sessions 8:00 am – 9:00 am Poster Session & Continental Breakfast Joint Meeting Evaluations Odd Numbered posters The AAP/ASCI/APSA Joint Meeting Planning Committee relies on presented your input to enhance its meetings. Following the Joint Meeting an 11:45 am – 1:30 pm Poster Session & Lunch online meeting evaluation will be emailed to all attendees. APSA Even Numbered posters attendees will receive a separate survey to help it planning committee presented enhance APSA-sponsored events at future AAP/ASCI/APSA Joint 1:30 pm – 2:00 pm Poster Dismantle Meetings. Your participation in this survey is greatly appreciated. Poster presenters should plan to be available on Saturday for their AAP/ASCI/APSA Joint Meeting Code of Conduct appointed poster presentation session and the resulting awards program later in the evening. We value your attendance. Our conference is dedicated to providing a harassment-free experience for everyone, regardless Best Poster Awards of gender, gender identity and expression, age, sexual orientation, disability, physical appearance, body size, race, ethnicity, or Best Poster Awards will be given in the amount of $1000 each. religious preference. AAP/ASCI/APSA do not tolerate harassment Members of the AAP, ASCI and APSA will judge posters on scientific of conference participants in any form. A participant engaging novelty, quality and clarity of presentation. Awards will be presented in harassing behavior will be warned and may be asked to leave on Saturday, April 6, from 9:45pm – 11:30pm in the Imperial Ballroom the conference with no refund. If you are being harassed, notice Foyer on Level B2. Poster presenters should plan on attending for that someone else is being harassed, or have any other concerns, award presentation. please contact a member of conference staff at the registration desk immediately. Conference staff and organizers are dedicated to making Wi-Fi Log-In & Code all participants feel safe for the duration of the conference. Network: Fairmont_Meeting Code: jointmtg 2 2019 AAP/ASCI/APSA Joint Meeting CONTINUING MEDICAL EDUCATION INFORMATION Target Audience Non Endorsement Statement By its nature, translational medicine -- the main focus of the Joint Cine-Med verifies that sound education principles have been Meeting -- draws on many different disciplines in order to better demonstrated in the development of this educational offering as expose the basis of normal physiology and disease-state pathology. evidenced by the review of its objectives, teaching plan, faculty, and Participants in the Joint Meeting learn about advances in areas of activity evaluation process. Cine-Med does not endorse or support biomedical research in which they are actively engaged, but they the actual opinions or material content as presented by the speaker(s) also learn about advances in areas outside their specific focus. and/or sponsoring organization. Presentations are focused on the scientific method and implementation of research strategies, which have broad application. Physician- Accreditation scientists (MD, MD/PhD, or other comparable training), ranging from early faculty appointment through tenured investigators, are the target In support of improving patient care, this activity has been planned audience. and implemented by Cine-Med and the Association of American Physicians, the American Society for Clinical Investigation, and Learning Objectives the American Physician-Scientists Association. Cine-Med is jointly At the conclusion of this activity, participants should be able to: accredited by the Accreditation Council for Continuing Medical • Describe important recent advances in the scientific basis of Education (ACCME), the Accreditation Council for Pharmacy disease and therapy Education (ACPE), and the American Nurses Credentialing Center • Describe novel strategies to address challenges to the physician- (ANCC), to provide continuing education for the healthcare team. scientist Ciné-Med designates this live activity for a maximum of 9.5 AMA • Be prepared to address gender discrimination in the medical PRA Category 1Credit(s)™. Physicians should claim only the credit workplace commensurate with the extent of their participation in the activity. • Explain recent breakthrough advances in the application of immunotherapy in human disease All other healthcare professionals will receive a Certificate of • Describe the roles that improved understanding of immunology Participation. For information on the applicability and acceptance advances and strategies can play in the potential treatment of of Certificates of Participation for activities designated forAMA PRA human disease Category 1 Credits™, consult your professional licensing board. Activity Goal Support This activity is designed to address the following core and team Supported by a grant from the National Institute of General Medical competencies: Sciences of the National Institutes of Health. Medical Knowledge and Professionalism Faculty Disclosure Summary Disclosure The following speakers have all indicated that they have Cine-Med adheres to accreditation requirements regarding industry No Relevant Financial Relationships to Disclose: support of continuing medical education. Disclosure of the planning E. Abel, MD, PhD; N. Brown; V. Dzau; L. Fan; B. Haynes, MD; committee and faculty’s commercial relationships will be made known R. Jagsi, MD; T. Johnson, MD; E. Miller, MD, PhD; D. Pan; J. Rodrigues; at the activity. Speakers are required to openly disclose any limitations D. Salvo; D. Segev, MD, PhD of data and/or any discussion of any off-label, experimental, or Continued On Page 4... investigational uses of drugs or devices in their presentations. - All Cine-Med employees and activity planners in control of content have indicated that they have no relevant financial relationships to disclose. 3 www.jointmeeting.org CONTINUING MEDICAL EDUCATION INFORMATION Faculty Disclosure Summary Continued Last First Suffix Commercial Interest For what role? Butte Atul See Opening Disclosure Slide See Opening Disclosure Slide Califf Robert MD Verily Life Sciences/Alphabet Senior Advisor Cytokinetics Board Member Merck / Astra Zeneca / Sanofi / Lilly Consultant Diamond Michael MD, PhD Moderna SAB member, equity options Inbos / Atreca Consultant Domchek Susan MD AstraZeneca / Clovis Honoraria, research funding for a clinical trial to my institution BMS Honoraria Ebert Benjamin MD, PhD Celgene Research Grant Erzurum Serpil MD ABIM Chair of the ABIM Pulmonary Disease Board Greka Anna MD, PhD Goldfinch Bio Financial interest June Carl MD Novartis Royalty payments for intellectual property license Tmunity Therapeutics Scientific Founder with founder’s equity Lazar Mitchell MD, PhD Eli Lilly / Pfizer
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