TABLE OF CONTENTS Volume 94, Number 4, January 28, 2020 .org/N

156 Qualitative study on the price of drugs for multiple sclerosis: Gaming the system D.M. Hartung, L. Alley, K.A. Johnston, and D.N. Bourdette Podcast

157 Apathy rating scores and β-amyloidopathy in patients with Parkinson disease at risk for cognitive decline Z. Zhou, M.L.T.M. Muller,¨ P. Kanel, J. Chua, V. Kotagal, D.I. Kaufer, R.L. Albin, K.A. Frey, and N.I. Bohnen

Cover Image 158 Cognitive correlates of cerebellar resting-state Significant clusters of the positive correlation between regional β-amyloid functional connectivity in Parkinson disease deposition and the apathy rating scores are depicted. The most B. Maiti, J.M. Koller, A.Z. Snyder, A.B. Tanenbaum, S.A. Norris, prominent findings localized to the bilateral frontal and cingulate cortices M.C. Campbell, and J.S. Perlmutter and nuclei accumbens regions. Stylized by Kaitlyn Aman Ramm, Neurology Editorial Assistant. 159 Objective subtle cognitive difficulties predict future See page 157 amyloid accumulation and neurodegeneration K.R. Thomas, K.J. Bangen, A.J. Weigand, E.C. Edmonds, C.G. Wong, ’ In Focus S. Cooper, L. Delano-Wood, and M.W. Bondi, for the Alzheimer s Disease Neuroimaging Initiative 147 Spotlight on the January 28 issue Editorial, p. 151

148 This Week’s Neurology® Podcast 160 Longitudinal optic neuritis-unrelated visual evoked potential changes in NMO spectrum disorders Editorials M. Ringelstein, J. Harmel, H. Zimmermann, A.U. Brandt, 149 Posterior circulation in children: Fearsome F. Paul, A. Haarmann, M. Buttmann, M.W. Hummert,¨ or not? C. Trebst, C. Schroeder, I. Ayzenberg, I. Kleiter, K. Hellwig, J. Havla, T. Kumpfel,¨ S. Jarius, B. Wildemann, P. Rommer, L.C. Jordan and B.S. Jacobs M.S. Weber, H. Pellkofer, L. Ropke,¨ C. Geis, N. Retzlaff, U. Zettl, M. Deppe, L. Klotz, K. Young, J.-P. Stellmann, 151 Do subtle cognitive deficits precede amyloid M. Kaste, P. Kermer, W. Marouf, F. Lauda, H. Tumani, J. Graf, A. Klistorner, H.-P. Hartung, O. Aktas, and accumulation? Cart before the horse P. Albrecht, on behalf of the Neuromyelitis Optica Study B.E. Snitz and A.M. Brickman Group (NEMOS)

Articles: Short Format 161 Clinical risk factors in SUDEP: A nationwide Full articles at Neurology.org/N population-based case-control study 153 Comparative study of posterior and anterior O. Sveinsson, T. Andersson, P. Mattsson, S. Carlsson, and T. Tomson circulation in childhood: Results from the CME Course Open Access Article Patient Page International Pediatric Stroke Study B. Goeggel Simonetti, M.F. Rafay, M. Chung, W.D. Lo, L.A. Beslow, What’s Happening L.L. Billinghurst, C.K. Fox, A. Pagnamenta, M. Steinlin, and M.T. Mackay, for the IPSS Study Group 162 What’s happening in Neurology® Clinical Practice CME Course Editorial, p. 149 163 What’s happening in Neurology® Neuroimmunology & 154 Sleep duration, midday napping, and sleep quality and Neuroinflammation incident stroke: The Dongfeng-Tongji cohort 164 What’s happening in Without Borders L. Zhou, K. Yu, L. Yang, H. Wang, Y. Xiao, G. Qiu, X. Liu, Y. Yuan, Y. Bai, X. Li, H. Yang, M. He, C. Wang, T. Wu, and X. Zhang Views & Reviews 155 Clinical phenotypes and classification algorithm for 165 Models of community-based primary care for epilepsy complex regional pain in low- and middle-income countries V. Dimova, M.S. Herrnberger, F. Escolano-Lozano, H.L. Rittner, G. Singh, M. Sharma, A. Krishnan, T. Dua, F. d’Aniello, E. Vlckova, C. Sommer, C. Maihofner,¨ and F. Birklein S. Manzoni, and J.W. Sander

Ahead of Print Articles and Editorials NPub.org/aheadofprint Continued

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Resident & Fellow Section 185 Author response: Value of witness observations ff 176 Resident & Fellow Rounds in the di erential diagnosis of transient loss of J.J. Millichap, and R.E. Strowd III consciousness M. Reuber and M. Chen 178 Clinical Reasoning: A 6-week-old infant with migrating focal seizures 185 Editors’ note: Pearls & Oy-sters: Challenging I. Bushlin, L. Smith, J.M. Peters, and C.M. El Achkar diagnosis of Gerstmann-Str¨aussler-Scheinker disease: Clinical and imaging findings e430 Mystery Case: epilepsy with ictal A. Ganesh and S. Galetta manifestation of Gerstmann syndrome H.M. Khoo, Y. Fujita, N. Tani, S. Oshino, K. Kagitani-Shimono, and 186 Reader response: Pearls & Oy-sters: Challenging H. Kishima diagnosis of Gerstmann-Str¨aussler-Scheinker disease: Clinical and imaging findings e434 Teaching NeuroImages: CNS pituitary-hypothalamic Langerhans cell histiocytosis in an adult M. Paucar G.A. Yeaney, V.R. Kshettry, and C. Isada 186 Author response: Pearls & Oy-sters: Challenging diagnosis of Gerstmann-Str¨aussler-Scheinker disease: Patient Page Clinical and imaging findings e436 Sudden unexpected death in epilepsy: Assessing the Y.H. Park, M.J. Kang, J. Suh, S.S. An, and S. Kim risk factors M. Pavlova Corrections 187 Neurologic aspects of sweating and its disorders Disputes & Debates: Editors’ Choice 184 Editors’ note: Value of witness observations in the 187 Outcome of endovascular therapy in stroke with large differential diagnosis of transient loss of vessel occlusion and mild symptoms consciousness 187 Amyloid and cerebrovascular burden divergently A. Ganesh and S. Galetta influence functional network changes over time

184 Reader response: Value of witness observations in 187 Child Neurology: Andersen-Tawil syndrome the differential diagnosis of transient loss of consciousness Department N.K. Sethi In the Next Issue of Neurology®

Neurology.org/N Offers Important Information to Patients and Their Families The Neurology® Patient Page provides: • A critical review of ground-breaking discoveries in neurologic research that are written especially for patients and their families • Up-to-date patient information about many neurologic diseases • Links to additional information resources for neurologic patients All Neurology Patient Page articles can be easily downloaded and printed, and may be reproduced to distribute for educational purposes. Click on the ‘Patients’ link on the home page (Neurology.org/N) for a complete index of Patient Pages.

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